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AD68593

159414-99-0 | Dmt-2'-f-dc(ac) amidite

Packsize Purity Availability Price Discounted Price    Quantity
250mg 95% in stock $60.00 $42.00 -   +
1g 95% in stock $135.00 $94.00 -   +
5g 95% in stock $412.00 $288.00 -   +
25g 95% in stock $1,623.00 $1,136.00 -   +
100g 95% in stock $5,327.00 $3,729.00 -   +

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*All prices are in USD.

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Description
Catalog Number: AD68593
Chemical Name: Dmt-2'-f-dc(ac) amidite
CAS Number: 159414-99-0
Molecular Formula: C41H49FN5O8P
Molecular Weight: 789.8286
MDL Number: MFCD12912404
SMILES: N#CCCOP(N(C(C)C)C(C)C)O[C@@H]1[C@@H](COC(c2ccc(cc2)OC)(c2ccc(cc2)OC)c2ccccc2)O[C@H]([C@@H]1F)n1ccc(nc1=O)NC(=O)C

 

Upstream Synthesis Route 
  • The 2'-F-Ac-dC Phosphoramidite is a crucial component in chemical synthesis, specifically in the field of DNA and RNA oligonucleotide synthesis. This phosphoramidite derivative is designed to facilitate the controlled incorporation of 2'-fluoro-2'-deoxycytidine (2'-F-dC) monomers during the automated synthesis of nucleic acids.By utilizing the 2'-F-Ac-dC Phosphoramidite, chemists can introduce 2'-fluoro modifications into the nucleic acid sequences, offering enhanced stability and affinity in the resulting oligonucleotides. This modification can play a significant role in various applications, such as gene expression studies, antisense oligonucleotide design, and the development of therapeutics targeting specific genetic sequences.With its precise reactivity and compatibility with automated solid-phase synthesis methods, the 2'-F-Ac-dC Phosphoramidite provides researchers with a powerful tool for customizing nucleic acid sequences with 2'-fluoro modifications, expanding the possibilities for advancing research and applications in molecular biology and drug development.
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