15992-83-3 | 1,8-Naphthyridin-2-amine

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$45.00	$32.00
1g	97%	in stock	$77.00	$54.00
10g	98%	in stock	$704.00	$493.00

Description

• Catalog Number: AA82142
• Chemical Name: 1,8-Naphthyridin-2-amine
• CAS Number: 15992-83-3
• Molecular Formula: C8H7N3
• Molecular Weight: 145.1613
• MDL Number: MFCD01250851
• SMILES: Nc1ccc2c(n1)nccc2

Computed Properties

• Complexity: 137
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• XLogP3: 1.1

Literature

• Synthesis and evaluation of fluorogenic 2-amino-1,8-naphthyridine derivatives for the detection of bacteria.

  Organic & biomolecular chemistry 20120407

• Effect of substituents of alloxazine derivatives on the selectivity and affinity for adenine in AP-site-containing DNA duplexes.

  Organic & biomolecular chemistry 20101107

• 2,2',4,4'-Tetra-methyl-7,7'-diazenediylbis(1,8-naphthyridin-1-ium) bis-(perchlorate).

  Acta crystallographica. Section E, Structure reports online 20090701

• Synthesis of dimeric 2-amino-1,8-naphthyridine and related DNA-binding molecules.

  Current protocols in nucleic acid chemistry 20080301

• Ratiometric fluorescence detection of pyrimidine/purine transversion by using a 2-amino-1,8-naphthyridine derivative.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060201

• Affinity labeling of a single guanine bulge.

  Journal of the American Chemical Society 20030730

• Assessment of the sequence dependency for the binding of 2-aminonaphthyridine to the guanine bulge.

  Bioorganic & medicinal chemistry 20030515

• Induction of a remarkable conformational change in a human telomeric sequence by the binding of naphthyridine dimer: inhibition of the elongation of a telomeric repeat by telomerase.

  Journal of the American Chemical Society 20030122

• The binding of naphthyridine tetramer to guanine-rich sequences.

  Nucleic acids research. Supplement (2001) 20030101

• Recognition of DNA mismatch structures.

  Nucleic acids research. Supplement (2001) 20020101

• Recognition of guanine-guanine mismatches by the dimeric form of 2-amino-1,8-naphthyridine.

  Journal of the American Chemical Society 20011219

• Complexation-induced unfolding of heterocyclic ureas. Simple foldamers equilibrate with multiply hydrogen-bonded sheetlike structures.

  Journal of the American Chemical Society 20011031

• Specific binding of 2-amino-1,8-naphthyridine into a single guanine bulge as evidenced by photooxidation of GG doublet.

  Bioorganic & medicinal chemistry letters 20010212