1608-26-0 | Hexamethylphosphorous triamide

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$19.00	$13.00
10g	98%	in stock	$79.00	$55.00
25g	98%	in stock	$118.00	$82.00

Description

• Catalog Number: AA87105
• Chemical Name: Hexamethylphosphorous triamide
• CAS Number: 1608-26-0
• Molecular Formula: C6H18N3P
• Molecular Weight: 163.200981
• MDL Number: MFCD00008301
• SMILES: CN(P(N(C)C)N(C)C)C
• NSC Number: 102707

Computed Properties

• Complexity: 74
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• XLogP3: 0.6

Upstream Synthesis Route

The N,N,N',N',N'',N''-Hexamethylphosphinetriamine, also known as HMPA, is a valuable reagent widely used in chemical synthesis for its unique properties and versatility. As a strong Lewis base and electron donor, HMPA is commonly employed as a coordinating solvent in various reactions to facilitate complexation with metal ions, thus promoting different chemical transformations. It is particularly useful in organometallic chemistry, where it can enhance the reactivity and selectivity of metal-catalyzed reactions by stabilizing reactive intermediates.Moreover, HMPA can act as a solubilizing agent for a wide range of compounds, including inorganic salts and transition metal complexes, enabling homogeneous reactions to take place more efficiently. Its ability to solvate and stabilize a variety of polar and coordination compounds makes HMPA a valuable tool in the synthesis of complex molecules and materials. Additionally, HMPA is known to promote reactions that involve sensitive functional groups or sterically hindered substrates by increasing the accessibility of reactive sites and facilitating the formation of key intermediates.Overall, the application of N,N,N',N',N'',N''-Hexamethylphosphinetriamine in chemical synthesis offers researchers a versatile and powerful tool to achieve challenging transformations and access new synthetic pathways in organic and inorganic chemistry.

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