16830-15-2 | Asiaticoside

Packsize	Purity	Availability	Price	Discounted Price
5mg	≥95%	in stock	$48.00	$34.00
10mg	≥95%	in stock	$88.00	$62.00
25mg	98% by HPLC	in stock	$160.00	$112.00
50mg	98% by HPLC	in stock	$232.00	$163.00
100mg	98% by HPLC	in stock	$360.00	$252.00
500mg	98% by HPLC	in stock	$1,035.00	$724.00
1000mg	98% by HPLC	in stock	$1,621.00	$1,135.00

Description

• Catalog Number: AA90548
• Chemical Name: Asiaticoside
• CAS Number: 16830-15-2
• Molecular Formula: C48H78O19
• Molecular Weight: 959.1215
• MDL Number: MFCD06642601
• SMILES: OCC1OC(OCC2OC(OC(=O)C34CCC(C(C4C4=CCC5C(C4(CC3)C)(C)CCC3C5(C)CC(C(C3(C)CO)O)O)C)C)C(C(C2O)O)O)C(C(C1OC1OC(C)C(C(C1O)O)O)O)O

Computed Properties

• Complexity: 1820
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 27
• Heavy Atom Count: 67
• Hydrogen Bond Acceptor Count: 19
• Hydrogen Bond Donor Count: 12
• Rotatable Bond Count: 10
• XLogP3: 0.1

Literature

• Isolation and identification of an anti-hepatitis B virus compound from Hydrocotyle sibthorpioides Lam.

  Journal of ethnopharmacology 20131125

• Improved in vitro and in vivo collagen biosynthesis by asiaticoside-loaded ultradeformable vesicles.

  Journal of controlled release : official journal of the Controlled Release Society 20120820

• Growth and asiaticoside production in multiple shoot cultures of a medicinal herb, Centella asiatica (L.) Urban, under the influence of nutrient manipulations.

  Journal of natural medicines 20120401

• Asiaticoside: attenuation of neurotoxicity induced by MPTP in a rat model of Parkinsonism via maintaining redox balance and up-regulating the ratio of Bcl-2/Bax.

  Pharmacology, biochemistry, and behavior 20120101

• Effect of asiaticoside on 99mTc-tetrofosmin and 99mTc-sestamibi uptake in MCF-7 cells.

  Journal of nuclear medicine technology 20111201

• Asiaticoside suppresses collagen expression and TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts.

  Archives of dermatological research 20111001

• Bioassay-guided isolation of anti-inflammatory, antinociceptive and wound healer glycosides from the flowers of Verbascum mucronatum Lam.

  Journal of ethnopharmacology 20110714

• In vitro inhibitory effects of asiaticoside and madecassoside on human cytochrome P450.

  Toxicology in vitro : an international journal published in association with BIBRA 20110601

• Investigating wound healing, tyrosinase inhibitory and antioxidant activities of the ethanol extracts of Salvia cryptantha and Salvia cyanescens using in vivo and in vitro experimental models.

  Journal of ethnopharmacology 20110426

• Wound healing acceleration effect of endemic Ononis species growing in Turkey.

  Journal of ethnopharmacology 20110426

• Interesting linkage between wound healing and hepatoprotective activities.

  Chemico-biological interactions 20110425

• [The cellular and molecular mechanism of inhibitory effect of asiaticoside on capsular contracture following breast augmentation].

  Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery 20110101

• In vitro biological evaluation of electrospun cellulose acetate fiber mats containing asiaticoside or curcumin.

  Journal of biomedical materials research. Part A 20100915

• Protective effects of Asiaticoside on acute liver injury induced by lipopolysaccharide/D-galactosamine in mice.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20100801

• In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica.

  Journal of ethnopharmacology 20100720

• Wound healing potential of Sambucus ebulus L. leaves and isolation of an active component, quercetin 3-O-glucoside.

  Journal of ethnopharmacology 20100504

• Upregulation of phytosterol and triterpene biosynthesis in Centella asiatica hairy roots overexpressed ginseng farnesyl diphosphate synthase.

  Plant cell reports 20100401

• Contact dermatitis due to Centella asiatica.

  Contact dermatitis 20100101

• Exploring the wound healing activity of Arnebia densiflora (Nordm.) Ledeb. by in vivo models.

  Journal of ethnopharmacology 20090706

• Enrichment and purification of madecassoside and asiaticoside from Centella asiatica extracts with macroporous resins.

  Journal of chromatography. A 20080606

• Antidepressant-like effect of asiaticoside in mice.

  Pharmacology, biochemistry, and behavior 20080501

• [Preparation of asiaticoside and madecassoside from the extract of Centella asiatica (L.) Urb using preparative high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20080501

• Inhibition of LPS-induced NO and PGE2 production by asiatic acid via NF-kappa B inactivation in RAW 264.7 macrophages: possible involvement of the IKK and MAPK pathways.

  International immunopharmacology 20080301

• Simultaneous quantitation of three major triterpenoid glycosides in Centella asiatica extracts by high performance liquid chromatography with evaporative light scattering detection.

  Biomedical chromatography : BMC 20080201

• Enhanced production of asiaticoside from hairy root cultures of Centella asiatica (L.) Urban elicited by methyl jasmonate.

  Plant cell reports 20071101

• [Inhibitiory action of asiaiticoside on collagen-induced arthritis in mice].

  Yao xue xue bao = Acta pharmaceutica Sinica 20070701

• Evaluation of anxiolytic properties of Gotukola--(Centella asiatica) extracts and asiaticoside in rat behavioral models.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20061101

• Anxiolytic-like effect of asiaticoside in mice.

  Pharmacology, biochemistry, and behavior 20061001

• Cytotoxic cycloartane triterpene saponins from Actaea asiatica.

  Journal of natural products 20061001

• Identification of triterpenoid compounds of Centella asiatica by thin-layer chromatography and mass spectrometry.

  Biomedical chromatography : BMC 20060201

• Cloning of a cDNA probably encoding oxidosqualene cyclase associated with asiaticoside biosynthesis from Centella asiatica (L.) Urban.

  Plant cell reports 20050701

• Inhibitory effects of Centella asiatica water extract and asiaticoside on inducible nitric oxide synthase during gastric ulcer healing in rats.

  Planta medica 20041201

• Stimulation of asiaticoside accumulation in the whole plant cultures of Centella asiatica (L.) urban by elicitors.

  Plant cell reports 20041101

• The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats.

  Life sciences 20040319

• Contact allergy to various ingredients of topical medicaments.

  Contact dermatitis 20030701

• In vitro keratinocyte antiproliferant effect of Centella asiatica extract and triterpenoid saponins.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20010501