1740-57-4 | Isophthalamide

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$24.00	$17.00
5g	96%	in stock	$50.00	$35.00
25g	>97.0%(N)	in stock	$96.00	$67.00
100g	96%	in stock	$299.00	$209.00

Description

• Catalog Number: AA92326
• Chemical Name: Isophthalamide
• CAS Number: 1740-57-4
• Molecular Formula: C8H8N2O2
• Molecular Weight: 164.1613
• MDL Number: MFCD00014801
• SMILES: NC(=O)c1cccc(c1)C(=O)N

Computed Properties

• Complexity: 183
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: -0.2

Literature

• Anion complexation and transport by isophthalamide and dipicolinamide derivatives: DNA plasmid transformation in E. coli.

  Journal of the American Chemical Society 20120822

• New H-bonding patterns in biphenyl-based synthetic lectins; pyrrolediamine bridges enhance glucose-selectivity.

  Organic & biomolecular chemistry 20120814

• Ion-pair recognition by a heteroditopic triazole-containing receptor.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20120514

• Binding of group 15 and group 16 oxides by a concave host containing an isophthalamide unit.

  Beilstein journal of organic chemistry 20120101

• N,N'-Bis(2,5-dichloro-phen-yl)isophthalamide.

  Acta crystallographica. Section E, Structure reports online 20110901

• From anion receptors to transporters.

  Accounts of chemical research 20110315

• Macrocycle breathing in [2]rotaxanes with tetralactam macrocycles.

  The Journal of organic chemistry 20110121

• Protein surface recognition using geometrically pure Ru(II) tris(bipyridine) derivatives.

  Chemical communications (Cambridge, England) 20110107

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Design and synthesis of 1,4-dihydropyridine derivatives as BACE-1 inhibitors.

  European journal of medicinal chemistry 20100601

• Anion-assisted complexation of paraquat by cryptands based on bis(m-phenylene)-[32]crown-10.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100525

• Organic nanotubes assembled from isophthalamides and their application as templates to fabricate Pt nanotubes.

  Chemical communications (Cambridge, England) 20090728

• Anion recognition by a macrobicycle based on a tetraoxadiaza macrocycle and an isophthalamide head unit.

  The Journal of organic chemistry 20090703

• Interlocked host anion recognition by an indolocarbazole-containing [2]rotaxane.

  Journal of the American Chemical Society 20090408

• Predicting efficient antenna ligands for Tb(III) emission.

  Inorganic chemistry 20090119

• Discovery of an orally efficaceous 4-phenoxypyrrolidine-based BACE-1 inhibitor.

  Bioorganic & medicinal chemistry letters 20080101

• Self-assembly of fluorescent inclusion complexes in competitive media including the interior of living cells.

  Journal of the American Chemical Society 20071205

• Potent and selective isophthalamide S2 hydroxyethylamine inhibitors of BACE1.

  Bioorganic & medicinal chemistry letters 20070615

• Design, synthesis, and X-ray structure of potent memapsin 2 (beta-secretase) inhibitors with isophthalamide derivatives as the P2-P3-ligands.

  Journal of medicinal chemistry 20070517

• Conformational control of HCl co-transporter: imidazole functionalised isophthalamide vs. 2,6-dicarboxamidopyridine.

  Chemical communications (Cambridge, England) 20070507

• Strong stacking between FH--N hydrogen-bonded foldamers and fullerenes: formation of supramolecular nano networks.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

• Frequency analysis of amide-linked rotaxane mimetics.

  The journal of physical chemistry. A 20061130

• Anion binding versus intramolecular hydrogen bonding in neutral macrocyclic amides.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20061010

• Design, synthesis, and evaluation of Leu*Ala hydroxyethylene-based non-peptide beta-secretase (BACE) inhibitors.

  Bioorganic & medicinal chemistry 20060701

• Structural and molecular recognition studies with acyclic anion receptors.

  Accounts of chemical research 20060701

• Anion-templated assembly of [2]rotaxanes.

  Organic & biomolecular chemistry 20060421

• Modulation of cell membrane disruption by pH-responsive pseudo-peptides through grafting with hydrophilic side chains.

  Journal of controlled release : official journal of the Controlled Release Society 20051102

• 'Twisted' isophthalamide analogues.

  Chemical communications (Cambridge, England) 20050214

• Molecular dynamics study of 2rotaxanes: influence of solvation and cation on co-conformation.

  The Journal of organic chemistry 20030613