-
Axonal protection achieved by blockade of sodium/calcium exchange in a new model of ischemia in vivo.
Neuropharmacology 20120901
-
TRPV1-mediated calcium signal couples with cannabinoid receptors and sodium-calcium exchangers in rat odontoblasts.
Cell calcium 20120801
-
Reverse-mode NCX current in mouse airway smooth muscle: Na(+) and voltage dependence, contributions to Ca(2+) influx and contraction, and altered expression in a model of allergen-induced hyperresponsiveness.
Acta physiologica (Oxford, England) 20120601
-
Ouabain stimulates atrial natriuretic peptide secretion via the endothelin-1/ET(B) receptor-mediated pathway in beating rabbit atria.
Life sciences 20120522
-
Effects of low glucose on carotid body chemoreceptor cell activity studied in cultures of intact organs and in dissociated cells.
American journal of physiology. Cell physiology 20120415
-
High potency inhibition of hERG potassium channels by the sodium-calcium exchange inhibitor KB-R7943.
British journal of pharmacology 20120401
-
Vasopressin and oxytocin excite MCH neurons, but not other lateral hypothalamic GABA neurons.
American journal of physiology. Regulatory, integrative and comparative physiology 20120401
-
Calcium dependence of damage to mouse motor nerve terminals following oxygen/glucose deprivation.
Experimental neurology 20120301
-
Molecular and functional characterization of the human platelet Na(+) /Ca(2+) exchangers.
British journal of pharmacology 20120201
-
PPADS, a P2X receptor antagonist, as a novel inhibitor of the reverse mode of the Na⁺/Ca²⁺ exchanger in guinea pig airway smooth muscle.
European journal of pharmacology 20120115
-
Investigation of mitochondrial dysfunction by sequential microplate-based respiration measurements from intact and permeabilized neurons.
PloS one 20120101
-
Rapamycin (sirolimus) protects against hypoxic damage in primary heart cultures via Na+/Ca2+ exchanger activation.
Life sciences 20110704
-
The protective effect of mitochondrial ATP-sensitive K+ channel opener, nicorandil, combined with Na+/Ca2+ exchange blocker KB-R7943 on myocardial ischemia-reperfusion injury in rat.
Cell biochemistry and biophysics 20110701
-
Mitochondrial and cytosolic calcium in rat hearts under high-K(+) cardioplegia and pyruvate: mechano-energetic performance.
Canadian journal of physiology and pharmacology 20110701
-
Effect of dexamethasone on Na+/Ca2+ exchanger in dendritic cells.
American journal of physiology. Cell physiology 20110601
-
Mechanistic distinction between activation and inhibition of (Na(+)+K(+))-ATPase-mediated Ca2+ influx in cardiomyocytes.
Biochemical and biophysical research communications 20110311
-
A role for orexin in central vestibular motor control.
Neuron 20110224
-
KB-R7943, an inhibitor of the reverse Na+ /Ca2+ exchanger, blocks N-methyl-D-aspartate receptor and inhibits mitochondrial complex I.
British journal of pharmacology 20110101
-
Inhibition of spontaneous activity of rabbit atrioventricular node cells by KB-R7943 and inhibitors of sarcoplasmic reticulum Ca(2+) ATPase.
Cell calcium 20110101
-
Na+/Ca2+ exchanger inhibitors inhibit neurite outgrowth in PC12 cells.
Journal of pharmacological sciences 20110101
-
Sodium-calcium exchange in intracellular calcium handling of human airway smooth muscle.
PloS one 20110101
-
Blockade of the sodium calcium exchanger exhibits anticonvulsant activity in a pilocarpine model of acute seizures in rats.
Brain research 20101217
-
Ca2+ paradox injury mediated through TRPC channels in mouse ventricular myocytes.
British journal of pharmacology 20101201
-
Molecular mechanisms underlying Ca2+-mediated motility of human pancreatic duct cells.
American journal of physiology. Cell physiology 20101201
-
KB-R7943 inhibits Na+-dependent Mg2+ efflux in rat ventricular myocytes.
The journal of physiological sciences : JPS 20101101
-
Kisspeptin directly excites anorexigenic proopiomelanocortin neurons but inhibits orexigenic neuropeptide Y cells by an indirect synaptic mechanism.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20100728
-
Cardiac basal metabolism: energetic cost of calcium withdrawal in the adult rat heart.
Acta physiologica (Oxford, England) 20100701
-
Inhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion.
Diabetes 20100701
-
Effects of sarcolemmal Ca(2+) entry, ryanodine function, and kinase inhibitors on a rabbit model of heart failure.
International heart journal 20100701
-
Electrophysiological characterization of store-operated and agonist-induced Ca2+ entry pathways in endothelial cells.
Pflugers Archiv : European journal of physiology 20100601
-
The 1.3 isoform of Na+-Ca 2+ exchanger expressed in guinea pig tracheal smooth muscle is less sensitive to KB-R7943.
Journal of physiology and biochemistry 20100601
-
Postconditioning in mouse hearts is inhibited by blocking the reverse mode of the sodium-calcium exchanger.
Interactive cardiovascular and thoracic surgery 20100501
-
Inhibition of sodium-calcium exchange by KB-R7943: Dodecylamine and sphingosine in transfected Chinese hamster ovary cells.
Cell calcium 20100501
-
Na+-Ca2+ exchanger contributes to Ca2+ extrusion in ATP-stimulated endothelium of intact rat aorta.
Biochemical and biophysical research communications 20100423
-
Calcium transport and homeostasis in gill cells of a freshwater crab Dilocarcinus pagei.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100301
-
KB-R7943 inhibits high glucose-induced endothelial ICAM-1 expression and monocyte-endothelial adhesion.
Biochemical and biophysical research communications 20100219
-
Neuroprotective effect of KB-R7943 against glutamate excitotoxicity is related to mild mitochondrial depolarization.
Neurochemical research 20100201
-
Different mechanisms of Ca2+ regulation that influence synaptic transmission: comparison between crayfish and Drosophila neuromuscular junctions.
Synapse (New York, N.Y.) 20091201
-
Involvement of Na+/Ca2+ exchanger in migration and contraction of rat cultured tendon fibroblasts.
The Journal of physiology 20091115
-
Reactive oxygen species directly modify sodium-calcium exchanger activity in a splice variant-dependent manner.
Journal of molecular and cellular cardiology 20091101
-
Digoxin and ouabain induce P-glycoprotein by activating calmodulin kinase II and hypoxia-inducible factor-1alpha in human colon cancer cells.
Toxicology and applied pharmacology 20091101
-
Pharmacological modifications of the stretch-induced effects on ventricular fibrillation in perfused rabbit hearts.
American journal of physiology. Heart and circulatory physiology 20091101
-
Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1.
The Journal of biological chemistry 20091002
-
Hypoxia-induced cytosolic calcium decrease is mediated primarily by the forward mode of Na(+)/Ca(2+) exchanger in smooth muscle cells of fetal ductus arteriosus.
Pediatric cardiology 20091001
-
The Na+/Ca2+ exchange inhibitor 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate (KB-R7943) also blocks ryanodine receptors type 1 (RyR1) and type 2 (RyR2) channels.
Molecular pharmacology 20090901
-
Dofetilide enhances the contractility of rat ventricular myocytes via augmentation of Na+-Ca 2+ exchange.
Cardiovascular drugs and therapy 20090601
-
Contribution of Na+/Ca2+ exchange current to the formation of delayed afterdepolarizations in intact rat ventricular muscle.
Journal of cardiovascular pharmacology 20090601
-
A key role for dense granule secretion in potentiation of the Ca2+ signal arising from store-operated calcium entry in human platelets.
Cell calcium 20090501
-
The Na+/Ca2+ exchanger inhibitor, KB-R7943, blocks a nonselective cation channel implicated in chemosensory transduction.
Journal of neurophysiology 20090301
-
Cardiac myocyte excitation by ultrashort high-field pulses.
Biophysical journal 20090218
-
Mitochondrial regulation of sarcoplasmic reticulum Ca2+ content in vascular smooth muscle cells.
Circulation research 20090102
-
Potential therapeutic effects of Na+/Ca2+ exchanger inhibition in cardiac diseases.
Current medicinal chemistry 20090101
-
New insights in the contribution of voltage-gated Na(v) channels to rat aorta contraction.
PloS one 20090101
-
Role of TRP channels and NCX in mediating hypoxia-induced [Ca(2+)](i) elevation in PC12 cells.
Respiratory physiology & neurobiology 20081231
-
Intracellular Na(+) modulates large conductance Ca(2+)-activated K (+) currents in human umbilical vein endothelial cells.
Pflugers Archiv : European journal of physiology 20081001
-
High-frequency fatigue of skeletal muscle: role of extracellular Ca(2+).
European journal of applied physiology 20081001
-
Na+/Ca2+ exchanger inhibitor ameliorates impaired endothelium-dependent Na+ relaxation induced by high glucose in rat aorta.
Clinical and experimental pharmacology & physiology 20081001
-
[Effects of Astragalus membranaceus on atrial dynamics and ANP secretion].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001
-
Endothelial nitric oxide attenuates Na+/Ca2+ exchanger-mediated vasoconstriction in rat aorta.
British journal of pharmacology 20080701
-
Attenuation of maitotoxin-induced cytotoxicity in rat aortic smooth muscle cells by inhibitors of Na+/Ca2+ exchange, and calpain activation.
Toxicon : official journal of the International Society on Toxinology 20080615
-
The ins and outs of calcium in heart failure.
Circulation research 20080606
-
An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes.
American journal of physiology. Heart and circulatory physiology 20080501
-
Cerebral microvascular nNOS responds to lowered oxygen tension through a bumetanide-sensitive cotransporter and sodium-calcium exchanger.
American journal of physiology. Heart and circulatory physiology 20080501
-
Ranolazine inhibits an oxidative stress-induced increase in myocyte sodium and calcium loading during simulated-demand ischemia.
Journal of cardiovascular pharmacology 20080501
-
The Na(+)/Ca(2+) exchanger inhibitor KB-R7943 activates large-conductance Ca(2+)-activated K(+) channels in endothelial and vascular smooth muscle cells.
European journal of pharmacology 20080317
-
[Role of sodium-calcium exchanger in the myocardial protection against ischemia-reperfusion injury].
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20080301
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Differential effects of the sodium calcium exchange inhibitor, KB-R7943, on ischemia and reperfusion injury in isolated guinea pig ventricular myocytes.
European journal of pharmacology 20080202
-
Angiotensin II-stimulated Ca2+ entry mechanisms in afferent arterioles: role of transient receptor potential canonical channels and reverse Na+/Ca2+ exchange.
American journal of physiology. Renal physiology 20080101
-
Cell culture alters Ca2+ entry pathways activated by store-depletion or hypoxia in canine pulmonary arterial smooth muscle cells.
American journal of physiology. Cell physiology 20080101
-
A key role for reverse Na+/Ca2+ exchange influenced by the actin cytoskeleton in store-operated Ca2+ entry in human platelets: evidence against the de novo conformational coupling hypothesis.
Cell calcium 20071201
-
SR Ca2+ refilling upon depletion and SR Ca2+ uptake rates during development in rabbit ventricular myocytes.
American journal of physiology. Cell physiology 20071201
-
Characterization of SN-6, a novel Na+/Ca2+ exchange inhibitor in guinea pig cardiac ventricular myocytes.
European journal of pharmacology 20071114
-
The participation of the Na+-Ca2+ exchanger in primary cardiac myofibroblast migration, contraction, and proliferation.
Journal of cellular physiology 20071101
-
Carbachol exhibited positive inotropic effect on rat ventricular myocytes via M₂ muscarinic receptors.
Sheng li xue bao : [Acta physiologica Sinica] 20071025
-
Diastolic Ca2+ overload caused by Na+/Ca2+ exchanger during the first minutes of reperfusion results in continued myocardial stunning.
European journal of pharmacology 20071015
-
The Na+/Ca2+ exchange inhibitor KB-R7943 potently blocks TRPC channels.
Biochemical and biophysical research communications 20070914
-
Changes in calcium dynamics following the reversal of the sodium-calcium exchanger have a key role in AMPA receptor-mediated neurodegeneration via calpain activation in hippocampal neurons.
Cell death and differentiation 20070901
-
Characterization of noradrenaline-induced increases in intracellular Ca2+ levels in Chinese hamster ovary cells stably expressing human alpha1A-adrenoceptor.
Journal of pharmacological sciences 20070901
-
Store-refilling involves both L-type calcium channels and reverse-mode sodium-calcium exchange in airway smooth muscle.
The European respiratory journal 20070801
-
Preservation of mitochondrial function may contribute to cardioprotective effects of Na+/Ca2+ exchanger inhibitors in ischaemic/reperfused rat hearts.
British journal of pharmacology 20070801
-
Functional coupling between the Na+/Ca2+ exchanger and nonselective cation channels during histamine stimulation in guinea pig tracheal smooth muscle.
American journal of physiology. Lung cellular and molecular physiology 20070701
-
The plasma membrane Na+/Ca2+ exchange inhibitor KB-R7943 is also a potent inhibitor of the mitochondrial Ca2+ uniporter.
British journal of pharmacology 20070701
-
Na+/Ca2+ exchange and regulation of cytoplasmic concentration of calcium in rat cerebellar neurons treated with glutamate.
Biochemistry. Biokhimiia 20070701
-
Acetylcholine-induced asynchronous calcium waves in intact human bronchial muscle bundle.
American journal of respiratory cell and molecular biology 20070501
-
Role of reverse mode Na+/Ca2+ exchanger in the cardioprotection of metabolic inhibition preconditioning in rat ventricular myocytes.
European journal of pharmacology 20070430
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Involvement of Na+-Ca2+ exchanger on metabotropic glutamate receptor 1-mediated [Ca2+]i transients in rat cerebellar Purkinje neurons.
Neuroscience 20070425
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[Na+/Ca2+ exchanger (NCX1) and cardiovascular disease].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070401
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CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury.
Cardiovascular research 20070301
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The role of Na+/Ca2+ exchanger in endothelin-1-aggravated hypoxia/reoxygenation-induced injury in renal epithelial cells.
Annals of the New York Academy of Sciences 20070301
-
The reverse mode of the Na(+)/Ca(2+) exchanger provides a source of Ca(2+) for store refilling following agonist-induced Ca(2+) mobilization.
American journal of physiology. Lung cellular and molecular physiology 20070201
-
Propofol modulates Na+-Ca2+ exchange activity via activation of protein kinase C in diabetic cardiomyocytes.
Anesthesiology 20070201
-
Calcium regulation in individual peripheral sensory nerve terminals of the rat.
The Journal of physiology 20070115
-
Effects of purified endogenous inhibitor of the Na+/Ca2+ exchanger on ouabain-induced arrhythmias in the atria and ventricle strips of guinea pig.
European journal of pharmacology 20061228
-
5-Hydroxytryptamine contributes significantly to a reflex pathway by which the duodenal mucosa protects itself from gastric acid injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20061201
-
The influence of sodium-calcium exchange inhibitors on rabbit lens ion balance and transparency.
Experimental eye research 20061101
-
Single alpha-domain constructs of the Na+/Ca2+ exchanger, NCLX, oligomerize to form a functional exchanger.
Biochemistry 20061003
-
Na+/Ca2+ exchanger modulates the flagellar wave pattern for the regulation of motility activation and chemotaxis in the ascidian spermatozoa.
Cell motility and the cytoskeleton 20061001
-
Muscarine activates the sodium-calcium exchanger via M receptors in basal forebrain neurons.
The European journal of neuroscience 20061001
-
Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus.
Circulation 20060926
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Novel role for K+-dependent Na+/Ca2+ exchangers in regulation of cytoplasmic free Ca2+ and contractility in arterial smooth muscle.
American journal of physiology. Heart and circulatory physiology 20060901
-
Loading rat heart myocytes with Mg2+ using low-[Na+] solutions.
The Journal of physiology 20060901
-
Anesthetic preconditioning enhances Ca2+ handling and mechanical and metabolic function elicited by Na+-Ca2+ exchange inhibition in isolated hearts.
Anesthesiology 20060901
-
Inhibition by SEA0400, a selective inhibitor of Na+/Ca2+ exchanger, of Na+ -dependent Ca2+ uptake and catecholamine release in bovine adrenal chromaffin cells.
Journal of pharmacological sciences 20060901
-
Quantitative fluorescence measurement of cardiac Na+/Ca2+ exchanger inhibition by kinetic analysis in stably transfected HEK293 cells.
Journal of pharmacological sciences 20060801
-
Cardioprotection via activation of protein kinase C-delta depends on modulation of the reverse mode of the Na+/Ca2+ exchanger.
Circulation 20060704
-
Effects of a Na+/Ca2+ exchanger inhibitor on pulmonary vein electrical activity and ouabain-induced arrhythmogenicity.
Cardiovascular research 20060601
-
High potassium concentrations protect inner and outer hair cells in the newborn rat culture from ischemia-induced damage.
Hearing research 20060501
-
Fundamental importance of Na+-Ca2+ exchange for the pacemaking mechanism in guinea-pig sino-atrial node.
The Journal of physiology 20060315
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Effects of caffeine, verapamil, lithium, and KB-R7943 on mechanics and energetics of rat myocardial bigeminies.
American journal of physiology. Heart and circulatory physiology 20060201
-
Sodium-dependent recovery of ionised magnesium concentration following magnesium load in rat heart myocytes.
Pflugers Archiv : European journal of physiology 20060201
-
Role of the Na+/Ca2+ exchanger in calcium homeostasis and human sperm motility regulation.
Cell motility and the cytoskeleton 20060201
-
Involvement of Na+/Ca2+ exchanger in catecholamine-induced increase in intracellular calcium in cardiomyocytes.
American journal of physiology. Heart and circulatory physiology 20060101
-
[Na+/Ca2+ exchanger(NCX1) and salt-sensitive hypertension].
Nihon rinsho. Japanese journal of clinical medicine 20060101
-
Sodium calcium exchange as a target for antiarrhythmic therapy.
Handbook of experimental pharmacology 20060101
-
Stretch-dependent modulation of [Na+]i, [Ca2+]i, and pHi in rabbit myocardium--a mechanism for the slow force response.
Cardiovascular research 20051201
-
The inhibitory effect of ouabain on the response of slowly adapting pulmonary stretch receptors to hyperinflation in the rabbit.
Life sciences 20051119
-
Na+-K+ pump activation inhibits endothelium-dependent relaxation by activating the forward mode of Na+/Ca2+ exchanger in mouse aorta.
American journal of physiology. Heart and circulatory physiology 20051101
-
Transport of extracellular l-arginine via cationic amino acid transporter is required during in vivo endothelial nitric oxide production.
American journal of physiology. Heart and circulatory physiology 20051001
-
Involvement of Na+-Ca2+ exchanger in intracellular Ca2+ increase and neuronal injury induced by polychlorinated biphenyls in human neuroblastoma SH-SY5Y cells.
The Journal of pharmacology and experimental therapeutics 20051001
-
Electrophysiological and molecular identification of voltage-gated sodium channels in murine vascular myocytes.
The Journal of physiology 20051001
-
Probing the endogenous Ca2+ buffers at the presynaptic terminals of the crayfish neuromuscular junction.
Journal of neurophysiology 20050701
-
Inhibition of the reverse mode of the Na+/Ca2+ exchange by KB-R7943 augments arrhythmogenicity in the canine heart during rapid heart rates.
Journal of electrocardiology 20050701
-
Effects of SEA0400 and KB-R7943 on Na+/Ca2+ exchange current and L-type Ca2+ current in canine ventricular cardiomyocytes.
Naunyn-Schmiedeberg's archives of pharmacology 20050701
-
Mechanism-based modeling of reduced inotropic responsiveness to digoxin in endotoxemic rat hearts.
European journal of pharmacology 20050502
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Therapeutic potential of novel Na+-Ca2+ exchange inhibitors in attenuating ischemia-reperfusion injury.
The Canadian journal of cardiology 20050501
-
Na+/Ca2+ exchanger activity modulates connective tissue growth factor mRNA expression in transforming growth factor beta1- and Des-Arg10-kallidin-stimulated myofibroblasts.
The Journal of biological chemistry 20050415
-
Na+/Ca2+ exchange inhibition protects the rat heart from ischemia-reperfusion injury by blocking energy-wasting processes.
American journal of physiology. Heart and circulatory physiology 20050401
-
Role of phosphorylation of Thr(17) residue of phospholamban in mechanical recovery during hypercapnic acidosis.
Cardiovascular research 20050401
-
Na(+)/Ca(2+) exchange regulates Ca(2+)-dependent duodenal mucosal ion transport and HCO(3)(-) secretion in mice.
American journal of physiology. Gastrointestinal and liver physiology 20050301
-
Protection of ischemic rat spinal cord white matter: Dual action of KB-R7943 on Na+/Ca2+ exchange and L-type Ca2+ channels.
Neuropharmacology 20050301
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Sodium channels are required during in vivo sodium chloride hyperosmolarity to stimulate increase in intestinal endothelial nitric oxide production.
American journal of physiology. Heart and circulatory physiology 20050101
-
Fowl (Gallus domesticus) sperm motility depends upon mitochondrial calcium cycling driven by extracellular sodium.
Biology of reproduction 20050101
-
Effects of Na+-Ca2+ exchanger activity on the alpha-amino-3-hydroxy-5-methyl-4-isoxazolone-propionate-induced Ca2+ influx in cerebellar Purkinje neurons.
Neuroscience 20050101
-
Cardioprotective effects of KB-R7943, a novel inhibitor of Na+/Ca2+ exchanger, on stunned myocardium in anesthetized dogs.
Journal of anesthesia 20050101
-
The role of Ca2+ transport across the plasma membrane for cell migration.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101
-
Functional differences of Na+/Ca2+ exchanger expression in Ca2+ transport system of smooth muscle of guinea pig stomach.
Canadian journal of physiology and pharmacology 20050101
-
Cross-talk between native plasmalemmal Na+/Ca2+ exchanger and inositol 1,4,5-trisphosphate-sensitive ca2+ internal store in Xenopus oocytes.
The Journal of biological chemistry 20041210
-
Endothelin-1 aggravates hypoxia/reoxygenation-induced injury in renal epithelial cells through the activation of a Na+/Ca2+ exchanger.
Journal of cardiovascular pharmacology 20041101
-
Systems analysis of digoxin kinetics and inotropic response in the rat heart: effects of calcium and KB-R7943.
American journal of physiology. Heart and circulatory physiology 20041001
-
Presynaptic alpha2-receptors regulate reverse Na+/Ca2+-exchange and transmitter release in Na+-loaded peripheral sympathetic nerves.
Neurochemistry international 20041001
-
Participation of Na/Ca-exchanger and sarcoplasmic reticulum in the high [K]-protection against ischaemia-reperfusion dysfunction in rat hearts.
Acta physiologica Scandinavica 20041001
-
High activity of K+-dependent plasmalemmal Na+/Ca2+ exchangers in hippocampal CA1 neurons.
Neuroreport 20040915
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Sodium-calcium exchanger contributes to membrane hyperpolarization of intact endothelial cells from rat aorta during acetylcholine stimulation.
British journal of pharmacology 20040901
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A sea urchin egg jelly peptide induces a cGMP-mediated decrease in sperm intracellular Ca(2+) before its increase.
Developmental biology 20040815
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Is modulation of sodium-calcium exchange a therapeutic option in heart failure?
Circulation research 20040806
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Effects of sodium-calcium exchange inhibitors, KB-R7943 and SEA0400, on aconitine-induced arrhythmias in guinea pigs in vivo, in vitro, and in computer simulation studies.
The Journal of pharmacology and experimental therapeutics 20040701
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Differential contribution of plasmalemmal Na/Ca exchange isoforms to sodium-dependent calcium influx and NMDA excitotoxicity in depolarized neurons.
Journal of neurochemistry 20040701
-
Na+/Ca2+ exchange inhibitors: potential drugs to mitigate the severity of ischemic injury.
Molecular pharmacology 20040701
-
Counteracting effects of NADPH oxidase and the Na+/Ca2+ exchanger on membrane repolarisation and store-operated uptake of Ca2+ by chemoattractant-activated human neutrophils.
Biochemical pharmacology 20040615
-
The potential of Na+/Ca2+ exchange blockers in the treatment of cardiac disease.
Expert opinion on investigational drugs 20040601
-
Ca(2+) signaling by TRPC3 involves Na(+) entry and local coupling to the Na(+)/Ca(2+) exchanger.
The Journal of biological chemistry 20040402
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Calcium dynamics and vasomotion in rat mesenteric arteries.
Journal of cardiovascular pharmacology 20040401
-
Development and application of Na+/Ca2+ exchange inhibitors.
Molecular and cellular biochemistry 20040401
-
Molecular determinants of Na+/Ca2+ exchange (NCX1) inhibition by SEA0400.
The Journal of biological chemistry 20040227
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KB-R7943 reveals possible involvement of Na(+)-Ca2+ exchanger in elevation of intracellular Ca2+ in rat carotid arterial myocytes.
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20040201
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[Effect of inhibitors of sodium-calcium exchangers on acetylcholine-induced hyperpolarization of endothelial cells in rat aorta].
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20040101
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Na(+) and Ca(2+) homeostasis pathways, cell death and protection after oxygen-glucose-deprivation in organotypic hippocampal slice cultures.
Neuroscience 20040101
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Aspartate release from rat hippocampal synaptosomes.
Neuroscience 20040101
-
Physiological role of the sodium-calcium exchanger in tracheal smooth muscle of guinea pig.
Journal of muscle research and cell motility 20040101
-
A low dose of angiotensin II increases inotropism through activation of reverse Na(+)/Ca(2+) exchange by endothelin release.
Cardiovascular research 20031201
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Ca2+-dependent modulation of intracellular Mg2+ concentration with amiloride and KB-R7943 in pig carotid artery.
The Journal of biological chemistry 20031128
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Influence of Na+-independent Cl--HCO3- exchange on the slow force response to myocardial stretch.
Circulation research 20031128
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Influence of lidocaine on ouabain-induced inotropic response in rat atria.
Biochemical pharmacology 20031101
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A novel and selective Na+/Ca2+ exchange inhibitor, SEA0400, improves ischemia/reperfusion-induced renal injury.
European journal of pharmacology 20031008
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Resting membrane potential regulates Na(+)-Ca2+ exchange-mediated Ca2+ overload during hypoxia-reoxygenation in rat ventricular myocytes.
The Journal of physiology 20030801
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Na(+)-Ca2+ exchange function underlying contraction frequency inotropy in the cat myocardium.
The Journal of physiology 20030801
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Does enhanced expression of the Na+-Ca2+ exchanger increase myocardial vulnerability to ischemia/reperfusion injury in rabbit hearts?
Molecular and cellular biochemistry 20030601
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Role of Na+/H+ exchanger in acetylcholine-mediated pulmonary artery contraction of spontaneously hypertensive rats.
European journal of pharmacology 20030319
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Differing cardioprotective efficacy of the Na+/Ca2+ exchanger inhibitors SEA0400 and KB-R7943.
American journal of physiology. Heart and circulatory physiology 20030301
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Role of nitric oxide and free radicals in cardioprotection by blocking Na+/H+ and Na+/Ca2+ exchange in rat heart.
European journal of pharmacology 20030214
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Attenuation of ischemia/reperfusion-induced renal injury in mice deficient in Na+/Ca2+ exchanger.
The Journal of pharmacology and experimental therapeutics 20030101
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Protective effects of SEA0400, a novel and selective inhibitor of the Na+/Ca2+ exchanger, on myocardial ischemia-reperfusion injuries.
European journal of pharmacology 20030101
-
Importance of Ca2+ influx by Na+/Ca2+ exchange under normal and sodium-loaded conditions in mammalian ventricles.
Molecular and cellular biochemistry 20030101
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Pharmacology of KB-R7943: a Na+-Ca2+ exchange inhibitor.
Cardiovascular drug reviews 20030101
-
Quantitative analysis of hyperosmotic and hypothermic blood-brain barrier opening.
Acta neurochirurgica. Supplement 20030101
-
In depolarized and glucose-deprived neurons, Na+ influx reverses plasmalemmal K+-dependent and K+-independent Na+/Ca2+ exchangers and contributes to NMDA excitotoxicity.
Journal of neurochemistry 20021201
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Negative and positive inotropic effects of propofol via L-type calcium channels and the sodium-calcium exchanger in rat cardiac trabeculae.
Anesthesiology 20021101
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[Functional analysis of Na+/Ca2+ exchanger using novel drugs and genetically engineered mice].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021101
-
KB-R7943, a Na+/Ca2+ exchange inhibitor, does not suppress ischemia/reperfusion arrhythmias nor digitalis arrhythmias in dogs.
Japanese journal of pharmacology 20021101
-
Electrophysiological studies of the cloned rat cardiac NCX1.1 in transfected HEK cells: a focus on the stoichiometry.
Annals of the New York Academy of Sciences 20021101
-
Pharmacology of Na+/Ca2+ exchanger.
Annals of the New York Academy of Sciences 20021101
-
Effect of KB-R7943 on oscillatory Na+/Ca2+ exchange current in guinea pig ventricular myocytes.
Annals of the New York Academy of Sciences 20021101
-
Inhibition of the Drosophila Na+/Ca2) exchanger, CALX1.1, by KB-R7943.
Annals of the New York Academy of Sciences 20021101
-
Modulation of exocytosis by the Na(+)/Ca(2+) exchanger of chromaffin cells.
Annals of the New York Academy of Sciences 20021001
-
Kb-R7943 prevents acute, atrial fibrillation-induced shortening of atrial refractoriness in anesthetized dogs.
Circulation 20020910
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Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility.
Circulation research 20020906
-
Effect of inhibition of Na(+)/Ca(2+) exchanger at the time of myocardial reperfusion on hypercontracture and cell death.
Cardiovascular research 20020901
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Lithium and KB-R7943 effects on mechanics and energetics of rat heart muscle.
Acta physiologica Scandinavica 20020901
-
Developmental changes of Ca(2+) handling in mouse ventricular cells from early embryo to adulthood.
Life sciences 20020802
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Involvement of Na(+)/Ca(2+) exchanger in endothelial NO production and endothelium-dependent relaxation.
American journal of physiology. Heart and circulatory physiology 20020801
-
Knockout mice for pharmacological screening: testing the specificity of Na+-Ca2+ exchange inhibitors.
Circulation research 20020726
-
Amiloride and KB-R7943 in outward Na+ /Ca2+ exchange current in guinea pig ventricular myocytes.
Journal of cardiovascular pharmacology 20020701
-
Blockade of the Na+-Ca2+ exchanger is more efficient than blockade of the Na+-H+ exchanger for protection of the myocardium from lethal reperfusion injury.
Cardiovascular drugs and therapy 20020701
-
Inhibition by KB-r7943 of the reverse mode of the Na+/Ca2+ exchanger reduces Ca2+ overload in ischemic-reperfused rat hearts.
Circulation journal : official journal of the Japanese Circulation Society 20020401
-
Instrumental role of Na+ in NMDA excitotoxicity in glucose-deprived and depolarized cerebellar granule cells.
Journal of neurochemistry 20020401
-
Autocrine stimulation of cardiac Na(+)-Ca(2+) exchanger currents by endogenous endothelin released by angiotensin II.
Circulation research 20020308
-
Synergistic effect of cold mannitol and Na(+)/Ca(2+) exchange blocker on blood-brain barrier opening.
Biochemical and biophysical research communications 20020301
-
Effect of SEA0400, a novel inhibitor of sodium-calcium exchanger, on myocardial ionic currents.
British journal of pharmacology 20020301
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Time course and mechanisms of phosphorylation of phospholamban residues in ischemia-reperfused rat hearts. Dissociation of phospholamban phosphorylation pathways.
Journal of molecular and cellular cardiology 20020101
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Role of Na(+)-Ca(2+) exchanger after traumatic or hypoxic/ischemic injury to spinal cord white matter.
The spine journal : official journal of the North American Spine Society 20020101
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Roles for mitochondrial and reverse mode Na+/Ca2+ exchange and the plasmalemma Ca2+ ATPase in post-tetanic potentiation at crayfish neuromuscular junctions.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20011215
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Reperfusion arrhythmias: new insights into the role of the Na(+)/Ca(2+) exchanger.
Journal of molecular and cellular cardiology 20011201
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Very low dose of the Na(+)/Ca(2+) exchange inhibitor, KB-R7943, protects ischemic reperfused aged Fischer 344 rat hearts: considerable strain difference in the sensitivity to KB-R7943.
Cardiovascular research 20011201
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KB-R7943. Kanebo.
Current opinion in investigational drugs (London, England : 2000) 20011201
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Gender influences [Ca(2+)](i) during metabolic inhibition in myocytes overexpressing the Na(+)-Ca(2+) exchanger.
Circulation 20011023
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Inhibition of Na(+)/Ca(2+) exchange by KB-R7943, a novel selective antagonist, attenuates phosphoethanolamine and free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury.
Brain research 20011019
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On the source of Ca(2+) activating the tonic component of contraction of myocytes of guinea pig heart.
Cardiovascular research 20011001
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Reperfusion-induced Ins(1,4,5)P(3) generation and arrhythmogenesis require activation of the Na(+)/Ca(2+) exchanger.
Journal of molecular and cellular cardiology 20011001
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Inhibition of Na+/Ca2+ exchange by KB-R7943: transport mode selectivity and antiarrhythmic consequences.
American journal of physiology. Heart and circulatory physiology 20010901
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Cardiac sodium-calcium exchanger: a double-edged sword.
Cardiovascular research 20010801
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Role of the reverse mode of the Na+/Ca2+ exchanger in reoxygenation-induced cardiomyocyte injury.
Cardiovascular research 20010801
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Inhibition of Na+/Ca2+ exchange with KB-R7943 or bepridil diminished mineral deposition by osteoblasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010801
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Differential roles of the sodium-calcium exchanger in renin secretion and renal vascular resistance.
Pflugers Archiv : European journal of physiology 20010801
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SEA0400, a novel and selective inhibitor of the Na+-Ca2+ exchanger, attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models.
The Journal of pharmacology and experimental therapeutics 20010701
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Sodium-calcium exchanger (NCX-1) and calcium modulation: NCX protein expression patterns and regulation of early heart development.
Developmental dynamics : an official publication of the American Association of Anatomists 20010701
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The effects of the Na(+)/Ca(++) exchange blocker on osmotic blood-brain barrier disruption.
Brain research 20010511
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Inhibition of aggregation of rabbit and human platelets induced by adrenaline and 5-hydroxytryptamine by KB-R7943, a Na(+)/Ca(2+) exchange inhibitor.
British journal of pharmacology 20010401
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Structural domains influencing sensitivity to isothiourea derivative inhibitor KB-R7943 in cardiac Nna(+)/Ca(2+) exchanger.
Molecular pharmacology 20010301
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The sodium pump modulates the influence of I(Na) on [Ca2+]i transients in mouse ventricular myocytes.
Biophysical journal 20010301
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KB-R7943, a selective Na+/Ca2+ exchange inhibitor, protects against ischemic acute renal failure in mice by inhibiting renal endothelin-1 overproduction.
Journal of cardiovascular pharmacology 20010301
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Pre- or post-ischemic treatment with a novel Na+/Ca2+ exchange inhibitor, KB-R7943, shows renal protective effects in rats with ischemic acute renal failure.
The Journal of pharmacology and experimental therapeutics 20010201
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Functional role of sodium-calcium exchange in the regulation of renal vascular resistance.
American journal of physiology. Renal physiology 20010101
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Protein kinase C suppresses spontaneous, transient, outwards K+ currents through modulation of the Na/Ca exchanger in guinea-pig gastric myocytes.
Pflugers Archiv : European journal of physiology 20010101
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[The Na+/Ca2+ exchanger as responsible for myocardial stunning].
Medicina 20010101
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Na(+)-K(+)-ATPase inhibition and depolarization induce glutamate release via reverse Na(+)-dependent transport in spinal cord white matter.
Neuroscience 20010101
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[Effect of KB-R7943 on Na(+)-Ca2+ exchange current in guinea pig ventricular myocytes].
Yao xue xue bao = Acta pharmaceutica Sinica 20010101
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ERK signaling mediates the induction of inflammatory cytokines by bufalin in human monocytic cells.
American journal of physiology. Cell physiology 20000301
