18642-23-4 | Psoralidin

Packsize	Purity	Availability	Price	Discounted Price
1mg	99%(HPLC)powder	in stock	$31.00	$22.00
5mg	99%(HPLC)powder	in stock	$100.00	$70.00
10mg	≥95%	in stock	$173.00	$121.00
25mg	>98.0%(HPLC)	in stock	$274.00	$192.00
100mg	≥95%	in stock	$915.00	$640.00

Description

• Catalog Number: AD33752
• Chemical Name: Psoralidin
• CAS Number: 18642-23-4
• Molecular Formula: C20H16O5
• Molecular Weight: 336.3380
• MDL Number: MFCD10566617
• SMILES: CC(=CCc1cc2c(cc1O)oc(=O)c1c2oc2c1ccc(c2)O)C

Computed Properties

• Complexity: 554
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 25
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 4.7

Literature

• The coumarin psoralidin enhances anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).

  Molecules (Basel, Switzerland) 20120529

• Retraction. Psoralidin, an herbal molecule, inhibits phosphatidylinositol 3-kinase-mediated Akt signaling in androgen-independent prostate cancer cells.

  Cancer prevention research (Philadelphia, Pa.) 20111101

• Psoralidin, a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation.

  Biochemical pharmacology 20110901

• [Variation of 4 kinds of compounds in Psoralea corylifolia processed by different methods].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110801

• [Study on the chemical constituents of Psoralea corylifolia].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110801

• Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways.

  European journal of pharmacology 20110110

• Screening Antitumor Compounds Psoralen and Isopsoralen from Psoralea corylifolia L. Seeds.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Enhanced TRAIL-mediated apoptosis in prostate cancer cells by the bioactive compounds neobavaisoflavone and psoralidin isolated from Psoralea corylifolia.

  Pharmacological reports : PR 20110101

• Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer.

  Molecular cancer therapeutics 20100901

• Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay.

  Journal of chromatography. A 20100820

• Inhibiting TNF-mediated signaling: a novel therapeutic paradigm for androgen independent prostate cancer.

  Apoptosis : an international journal on programmed cell death 20100201

• Psoralea corylifolia Linn.-'Kushtanashini'.

  Pharmacognosy reviews 20100101

• Induction of quinone reductase activity by psoralidin isolated from Psoralea corylifolia in mouse hepa 1c1c7 cells.

  Archives of pharmacal research 20090701

• Total synthesis of psoralidin, an anticancer natural product.

  The Journal of organic chemistry 20090403

• Psoralidin, an herbal molecule, inhibits phosphatidylinositol 3-kinase-mediated Akt signaling in androgen-independent prostate cancer cells.

  Cancer prevention research (Philadelphia, Pa.) 20090301

• Identification of a potent herbal molecule for the treatment of breast cancer.

  BMC cancer 20090101

• [Studies on chemical constituents from seed of Psoralea corylifolia].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080601

• Transcriptional regulation of corticotrophin releasing factor gene by furocoumarins isolated from seeds of Psoralea corylifolia.

  Life sciences 20080523

• Antidepressant-like effects of psoralidin isolated from the seeds of Psoralea Corylifolia in the forced swimming test in mice.

  Progress in neuro-psychopharmacology & biological psychiatry 20080215

• Chemical fingerprint and quantitative analysis of fructus psoraleae by high-performance liquid chromatography.

  Journal of separation science 20070401

• Bioactive constituents from Chinese natural medicines. XX. Inhibitors of antigen-induced degranulation in RBL-2H3 cells from the seeds of Psoralea corylifolia.

  Chemical & pharmaceutical bulletin 20070101

• [Isolation and structure identification of a new isoflavone from Psoralea corylifolias].

  Yao xue xue bao = Acta pharmaceutica Sinica 20060101

• Fingerprint analysis of Psoralea corylifolia L. by HPLC and LC-MS.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050705

• In vitro protein tyrosine phosphatase 1B inhibitory phenols from the seeds of Psoralea corylifolia.

  Planta medica 20050101

• Cytotoxic constituents of Psoralea corylifolia.

  Archives of pharmacal research 20010601