-
Isoalantolactone induces apoptosis through reactive oxygen species-dependent upregulation of death receptor 5 in human esophageal cancer cells.
Toxicology and applied pharmacology 20180801
-
Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes.
Toxicology and applied pharmacology 20180601
-
Nano-sized iron particles may induce multiple pathways of cell death following generation of mistranscripted RNA in human corneal epithelial cells.
Toxicology in vitro : an international journal published in association with BIBRA 20170801
-
Quercetin simultaneously induces G(0) /G(1) -phase arrest and caspase-mediated crosstalk between apoptosis and autophagy in human leukemia HL-60 cells.
Environmental toxicology 20170701
-
Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells.
The Journal of biological chemistry 20170519
-
Inhibition of ROS production, autophagy or apoptosis signaling reversed the anticancer properties of Antrodia salmonea in triple-negative breast cancer (MDA-MB-231) cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170501
-
Apoptosis inducing factor gene depletion inhibits zearalenone-induced cell death in a goat Leydig cell line.
Reproductive toxicology (Elmsford, N.Y.) 20170101
-
Caspase-Independent Apoptosis Induced by Reperfusion Following Ischemia without Bile Duct Occlusion in Rat Liver.
Biological & pharmaceutical bulletin 20170101
-
Tetrachlorobenzoquinone Stimulates NLRP3 Inflammasome-Mediated Post-Translational Activation and Secretion of IL-1β in the HUVEC Endothelial Cell Line.
Chemical research in toxicology 20160321
-
Stimulating basal mitochondrial respiration decreases doxorubicin apoptotic signaling in H9c2 cardiomyoblasts.
Toxicology 20150806
-
The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis.
Biological & pharmaceutical bulletin 20150101
-
Programmed cell death induced by (-)-8,9-dehydroneopeltolide in human promyelocytic leukemia HL-60 cells under energy stress conditions.
Marine drugs 20141101
-
TRAF2 inhibits TRAIL- and CD95L-induced apoptosis and necroptosis.
Cell death & disease 20141001
-
Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells.
International journal of molecular medicine 20140601
-
Disuccinyl betulin triggers metacaspase-dependent endonuclease G-mediated cell death in unicellular protozoan parasite Leishmania donovani.
Antimicrobial agents and chemotherapy 20140401
-
The C-terminal domain of the long form of cellular FLICE-inhibitory protein (c-FLIPL) inhibits the interaction of the caspase 8 prodomain with the receptor-interacting protein 1 (RIP1) death domain and regulates caspase 8-dependent nuclear factor κB (NF-κB) activation.
The Journal of biological chemistry 20140214
-
Matrix metalloproteinase-9 is involved in chronic lymphocytic leukemia cell response to fludarabine and arsenic trioxide.
PloS one 20140101
-
Aneugenic potential of the anticancer drugs melphalan and chlorambucil. The involvement of apoptosis and chromosome segregation regulating proteins.
Journal of applied toxicology : JAT 20130701
-
Acute phorbol ester treatment inhibits thapsigargin-induced cell death in porcine aortic smooth muscle cells.
European journal of pharmacology 20120705
-
Increased expression of stefin B in the nucleus of T98G astrocytoma cells delays caspase activation.
Frontiers in molecular neuroscience 20120101
-
Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells.
Toxicology letters 20111030
-
Polyalkoxybenzenes from plants. 5. Parsley seed extract in synthesis of azapodophyllotoxins featuring strong tubulin destabilizing activity in the sea urchin embryo and cell culture assays.
Journal of medicinal chemistry 20111027
-
Generation of 'Unnatural Natural Product' library and identification of a small molecule inhibitor of XIAP.
Bioorganic & medicinal chemistry 20110715
-
MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis.
Cell death & disease 20110101
-
Amyloid precursor protein binding protein Fe65 is cleaved by caspases during DNA damage-induced apoptosis.
Biological & pharmaceutical bulletin 20110101
-
Gene-specific differential response to anti-apoptotic therapies in zebrafish models of ocular coloboma.
Molecular vision 20110101
-
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters 20101101
-
High-mobility group box-1 protein and keratin-18, circulating serum proteins informative of acetaminophen-induced necrosis and apoptosis in vivo.
Toxicological sciences : an official journal of the Society of Toxicology 20091201
-
Oligomerized tumor necrosis factor-related apoptosis inducing ligand strongly induces cell death in myeloma cells, but also activates proinflammatory signaling pathways.
The FEBS journal 20091201
-
Turnover of newborn olfactory bulb neurons optimizes olfaction.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20090930
-
Involvement of the p53 tumor-suppressor protein in the development of antinociceptive tolerance to morphine.
Neuroscience letters 20090206
-
Sensitization by 5-azacytidine toward death receptor-induced hepatic apoptosis.
The Journal of pharmacology and experimental therapeutics 20090101
-
Programmed necrotic cell death induced by complement involves a Bid-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950) 20090101
-
Dihydrocapsaicin (DHC), a saturated structural analog of capsaicin, induces autophagy in human cancer cells in a catalase-regulated manner.
Autophagy 20081101
-
Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues.
The Journal of biological chemistry 20080704
-
A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity.
Nature chemical biology 20080601
-
Identification of RIP1 kinase as a specific cellular target of necrostatins.
Nature chemical biology 20080501
-
Caspase inhibitor facilitates recovery of hearing by protecting the cochlear lateral wall from acute cochlear mitochondrial dysfunction.
Journal of neuroscience research 20080101
-
Caspase inhibition reduces lymphocyte apoptosis and improves host immune responses to Trypanosoma cruzi infection.
European journal of immunology 20070301
-
A calpain-like protease inhibits autophagic cell death.
Autophagy 20070101
-
zVAD-fmk, unlike BocD-fmk, does not inhibit caspase-6 acting on 14-3-3/Bad pathway in apoptosis of p815 mastocytoma cells.
Experimental & molecular medicine 20061231
-
Caspase activation contributes to endotoxin-induced diaphragm weakness.
Journal of applied physiology (Bethesda, Md. : 1985) 20060601
-
Cancer cell mitochondria are direct proapoptotic targets for the marine antitumor drug lamellarin D.
Cancer research 20060315
-
Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20050810
-
Preferential cell death of CD8+ effector memory (CCR7-CD45RA-) T cells by hydrogen peroxide-induced oxidative stress.
Journal of immunology (Baltimore, Md. : 1950) 20050515
-
Phenoxodiol, a novel isoflavone, induces G1 arrest by specific loss in cyclin-dependent kinase 2 activity by p53-independent induction of p21WAF1/CIP1.
Cancer research 20050415
-
Sensitization of stefin B-deficient thymocytes towards staurosporin-induced apoptosis is independent of cysteine cathepsins.
FEBS letters 20050411
-
Acetoxycycloheximide (E-73) rapidly induces apoptosis mediated by the release of cytochrome c via activation of c-Jun N-terminal kinase.
Biochemical pharmacology 20050215
-
Inhibition of malignant glioma cell growth by a survivin mutant retrovirus.
Human gene therapy 20050201
-
Human cytomegalovirus proteins encoded by UL37 exon 1 protect infected fibroblasts against virus-induced apoptosis and are required for efficient virus replication.
The Journal of general virology 20041201
-
Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover.
Chemistry & biology 20041201
-
Caspase inhibition protects against reovirus-induced myocardial injury in vitro and in vivo.
Journal of virology 20041001
-
p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L).
Experimental cell research 20040815
-
Effects of chloride and potassium channel blockers on apoptotic cell shrinkage and apoptosis in cortical neurons.
Pflugers Archiv : European journal of physiology 20040601
-
Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappa B and induction of apoptosis.
Oncogene 20040401
-
N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway.
Molecular and cellular biology 20040401
-
Overexpression of phospholipase D prevents actinomycin D-induced apoptosis through potentiation of phosphoinositide 3-kinase signalling pathways in Chinese-hamster ovary cells.
The Biochemical journal 20040301
-
Antirestenotic effects of a locally delivered caspase inhibitor in a balloon injury model.
Circulation 20040106
-
Cephalostatin 1 selectively triggers the release of Smac/DIABLO and subsequent apoptosis that is characterized by an increased density of the mitochondrial matrix.
Cancer research 20031215
-
Involvement of Akt in mitochondria-dependent apoptosis induced by a cdc25 phosphatase inhibitor naphthoquinone analog.
FEBS letters 20031204
-
Possible role of interleukin-6 in PC12 cell death induced by MPP+ and tetrahydroisoquinoline.
Journal of pharmacological sciences 20031201
-
Lack of a functional p21WAF1/CIP1 gene accelerates caspase-independent apoptosis induced by cisplatin in renal cells.
American journal of physiology. Renal physiology 20030901
-
Involvement of oxidative stress in apoptosis induced by a mixture of isothiazolinones in normal human keratinocytes.
The Journal of investigative dermatology 20030801
-
Antioxidant dietary deficiency induces caspase activation in chick skeletal muscle cells.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20030801
-
Caspase inhibitors promote vestibular hair cell survival and function after aminoglycoside treatment in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20030709
-
Paraoxon induces apoptosis in EL4 cells via activation of mitochondrial pathways.
Toxicology and applied pharmacology 20030701
-
Caspase-dependent cell death mediates the early phase of aortic hypertrophy regression in losartan-treated spontaneously hypertensive rats.
Circulation research 20030418
-
Mitochondrial membrane permeabilization and superoxide production during apoptosis. A single-cell analysis.
The Journal of biological chemistry 20030411
-
Slight impairment of Na+,K+-ATPase synergistically aggravates ceramide- and beta-amyloid-induced apoptosis in cortical neurons.
Brain research 20021115
-
Caspase-independent phosphatidylserine exposure during apoptosis of primary T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 20021101
-
Grape seed extract induces apoptotic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c release.
Carcinogenesis 20021101
-
An ex vivo murine model to study poliovirus-induced apoptosis in nerve cells.
The Journal of general virology 20020801
-
Mitochondrial voltage-dependent anion channel is involved in dopamine-induced apoptosis.
Journal of neurochemistry 20020701
-
Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria.
Hepatology (Baltimore, Md.) 20020601
-
Insulin-like growth factor binding protein-related protein 1 inhibits proliferation of MCF-7 breast cancer cells via a senescence-like mechanism.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 20020501
-
Ionic mechanism of ouabain-induced concurrent apoptosis and necrosis in individual cultured cortical neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20020215
-
Higher pH promotes megakaryocytic maturation and apoptosis.
Stem cells (Dayton, Ohio) 20020101
-
15-deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors.
The Journal of biological chemistry 20011012
-
Mechanism of apoptosis in HL-60 cells induced by n-3 and n-6 polyunsaturated fatty acids.
Biochemical pharmacology 20011001
-
Caspase-dependent and serine protease-dependent DNA fragmentation of myocytes in the ischemia-reperfused rabbit heart: these inhibitors do not reduce infarct size.
Japanese circulation journal 20011001
-
Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways.
Journal of neurochemistry 20011001
-
Helenalin triggers a CD95 death receptor-independent apoptosis that is not affected by overexpression of Bcl-x(L) or Bcl-2.
Cancer research 20010801
-
Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria.
Cell death and differentiation 20010801
-
Caspase-resistant vimentin suppresses apoptosis after photodynamic treatment with a silicon phthalocyanine in Jurkat cells.
Archives of biochemistry and biophysics 20010601
-
Apoptosis and chemokine induction after renal ischemia-reperfusion.
Transplantation 20010415
-
Possible changes in expression of chemotaxin LECT2 mRNA in mouse liver after concanavalin A-induced hepatic injury.
Biological & pharmaceutical bulletin 20010401
-
A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles.
Cancer research 20010115
-
Role of K(+) efflux in apoptosis induced by AMPA and kainate in mouse cortical neurons.
Neuroscience 20010101
-
Structure/Function analysis of p55 tumor necrosis factor receptor and fas-associated death domain. Effect on necrosis in L929sA cells.
The Journal of biological chemistry 20001201
-
Bisphosphonates induce breast cancer cell death in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20001101
-
Suicidal differential housekeeping gene activity in apoptosis induced by DCNP.
Apoptosis : an international journal on programmed cell death 20001001
-
Mechanisms to prevent the toxicity of chronic neuroinflammation on forebrain cholinergic neurons.
European journal of pharmacology 20000818
-
Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro.
Biochemical pharmacology 20000715
-
E1A overcomes the apoptosis block in BCR-ABL+ leukemia cells and renders cells susceptible to induction of apoptosis by chemotherapeutic agents.
Cancer research 20000715
-
A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis.
Journal of neurochemistry 20000601
-
The involvement of caspases in the CD95(Fas/Apo-1)- but not swelling-induced cellular taurine release from Jurkat T-lymphocytes.
Pflugers Archiv : European journal of physiology 20000501
-
Molecular determinants of apoptosis induced by the cytotoxic ribonuclease onconase: evidence for cytotoxic mechanisms different from inhibition of protein synthesis.
Cancer research 20000401
-
Prevention of lymphocyte cell death in sepsis improves survival in mice.
Proceedings of the National Academy of Sciences of the United States of America 19991207
-
Human papillomavirus type 16 E6-enhanced susceptibility of L929 cells to tumor necrosis factor alpha correlates with increased accumulation of reactive oxygen species.
The Journal of biological chemistry 19990827
-
Caspase inhibition in camptothecin-treated U-937 cells is coupled with a shift from apoptosis to transient G1 arrest followed by necrotic cell death.
Cancer research 19990801
-
Geranylgeranylacetone induces apoptosis in HL-60 cells.
Cell structure and function 19990601
-
Signaling pathway activated during apoptosis of the prostate cancer cell line LNCaP: overexpression of caspase-7 as a new gene therapy strategy for prostate cancer.
Cancer research 19990115
-
Investigation of glucocorticoid-induced apoptotic pathway: processing of caspase-6 but not caspase-3.
Cell death and differentiation 19981201
-
Caspase-independent cell death induced by anti-CD2 or staurosporine in activated human peripheral T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 19981001
-
Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways.
The Journal of experimental medicine 19980907
-
Distinct steps in DNA fragmentation pathway during camptothecin-induced apoptosis involved caspase-, benzyloxycarbonyl- and N-tosyl-L-phenylalanylchloromethyl ketone-sensitive activities.
Cancer research 19980715
-
Death of tumor cells after intracellular acidification is dependent on stress-activated protein kinases (SAPK/JNK) pathway activation and cannot be inhibited by Bcl-2 expression or interleukin 1beta-converting enzyme inhibition.
Cancer research 19980701
-
Proteasome activities decrease during dexamethasone-induced apoptosis of thymocytes.
The Biochemical journal 19980601
-
Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor.
Circulation 19980127
-
Activation of PKCalpha downstream from caspases during apoptosis induced by 7-hydroxystaurosporine or the topoisomerase inhibitors, camptothecin and etoposide, in human myeloid leukemia HL60 cells.
The Journal of biological chemistry 19971212
-
Different interleukin-1 beta converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli.
The Journal of experimental medicine 19961201