189197-69-1 | Ro 48-8071 fumarate

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$12.00	$9.00
5mg	95%	in stock	$16.00	$11.00
10mg	95%	in stock	$29.00	$20.00
25mg	98%	in stock	$54.00	$38.00
50mg	98%	in stock	$70.00	$49.00

Description

• Catalog Number: AB16488
• Chemical Name: Ro 48-8071 fumarate
• CAS Number: 189197-69-1
• Molecular Formula: C27H31BrFNO6
• Molecular Weight: 564.4405
• MDL Number: MFCD05865242
• SMILES: OC(=O)/C=C/C(=O)O.C=CCN(CCCCCCOc1ccc(c(c1)F)C(=O)c1ccc(cc1)Br)C

Computed Properties

• Complexity: 587
• Covalently-Bonded Unit Count: 2
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 36
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 14

Literature

• Cytotoxic effects of combination of oxidosqualene cyclase inhibitors with atorvastatin in human cancer cells.

  Journal of medicinal chemistry 20120614

• Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents.

  Bioorganic & medicinal chemistry letters 20090201

• Synthesis and structure-activity studies of novel orally active non-terpenoic 2,3-oxidosqualene cyclase inhibitors.

  Journal of medicinal chemistry 20030717