19408-46-9 | Kasugamycin hydrochloride

Packsize	Purity	Availability	Price	Discounted Price
100mg	≥70%	in stock	$58.00	$41.00
1g	98%	in stock	$90.00	$63.00
5g	98%	in stock	$267.00	$187.00
10g	98%	in stock	$387.00	$271.00
25g	98%	in stock	$791.00	$554.00

Description

• Catalog Number: AI43554
• Chemical Name: Kasugamycin hydrochloride
• CAS Number: 19408-46-9
• Molecular Formula: C14H26ClN3O9
• Molecular Weight: 415.8239
• MDL Number: MFCD00058459
• SMILES: N[C@H]1C[C@H](NC(=N)C(=O)O)[C@H](O[C@@H]1O[C@@H]1[C@@H](O)[C@@H](O)[C@H]([C@@H]([C@H]1O)O)O)C.Cl

Computed Properties

• Complexity: 532
• Covalently-Bonded Unit Count: 2
• Defined Atom Stereocenter Count: 8
• Heavy Atom Count: 27
• Hydrogen Bond Acceptor Count: 11
• Hydrogen Bond Donor Count: 9
• Rotatable Bond Count: 4

Literature

• Residues and dynamics of kasugamycin in chilli and soil.

  Bulletin of environmental contamination and toxicology 20120901

• Translation-independent localization of mRNA in E. coli.

  Science (New York, N.Y.) 20110225

• Evaluation of kasugamycin for fire blight management, effect on nontarget bacteria, and assessment of kasugamycin resistance potential in Erwinia amylovora.

  Phytopathology 20110201

• The aminoglycoside resistance methyltransferases from the ArmA/Rmt family operate late in the 30S ribosomal biogenesis pathway.

  RNA (New York, N.Y.) 20110201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Analysis of antibiotic fungicide kasugamycin in irrigation water by high performance liquid chromatography.

  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20100701

• Exposure effect of fungicide kasugamycin on bacterial community in natural river sediment.

  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20100701

• Translation initiation region dependency of translation initiation in Escherichia coli by IF1 and kasugamycin.

  The FEBS journal 20100601

• Control of glutamate receptor 2 (GluR2) translational initiation by its alternative 3' untranslated regions.

  Molecular pharmacology 20091201

• ksgA mutations confer resistance to kasugamycin in Neisseria gonorrhoeae.

  International journal of antimicrobial agents 20090401

• Less is more for leaderless mRNA translation.

  Molecular cell 20090130

• An unexpected type of ribosomes induced by kasugamycin: a look into ancestral times of protein synthesis?

  Molecular cell 20090130

• The chlamydial functional homolog of KsgA confers kasugamycin sensitivity to Chlamydia trachomatis and impacts bacterial fitness.

  BMC microbiology 20090101

• Structural analysis of kasugamycin inhibition of translation.

  Nature structural & molecular biology 20061001

• The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.

  Nature structural & molecular biology 20061001

• Antibiotic blocks mRNA path on the ribosome.

  Nature structural & molecular biology 20061001

• DNA sequencing and transcriptional analysis of the kasugamycin biosynthetic gene cluster from Streptomyces kasugaensis M338-M1.

  The Journal of antibiotics 20060101

• Role of mitochondrial ribosome-dependent translation in germline formation in Drosophila embryos.

  Mechanisms of development 20051001

• New media for the semiselective isolation and enumeration of Xanthomonas campestris pv. mangiferaeindicae, the causal agent of mango bacterial black spot.

  Journal of applied microbiology 20050101

• Human mitochondrial transcription factor B1 methylates ribosomal RNA at a conserved stem-loop.

  Nature genetics 20030101

• kasT gene of Streptomyces kasugaensis M338-M1 encodes a DNA-binding protein which binds to intergenic region of kasU-kasJ in the kasugamycin biosynthesis gene cluster.

  The Journal of antibiotics 20021201

• Differential inhibition of 30S and 70S translation initiation complexes on leaderless mRNA by kasugamycin.

  Biochemical and biophysical research communications 20021004

• Instruction of translating ribosome by nascent peptide.

  Science (New York, N.Y.) 20020913

• Establishment of a new cross of the rice blast fungus derived from Japanese differential strain Ina168 and hermaphroditic rice pathogen Guy11.

  Bioscience, biotechnology, and biochemistry 20010701

• Coordination mode and reactivity of copper(II) complexes with kasugamycin.

  Journal of inorganic biochemistry 20010601

• Continuous culture of immobilized streptomyces cells for kasugamycin production.

  Biotechnology progress 20010101