19767-45-4 | sodium 2-sulfanylethane-1-sulfonate

Packsize	Purity	Availability	Price	Discounted Price
1g	90%	in stock	$15.00	$10.00
5g	90%	in stock	$22.00	$15.00
25g	90%	in stock	$93.00	$65.00
500g	94%	in stock	$1,497.00	$1,048.00

Description

• Catalog Number: AB07319
• Chemical Name: sodium 2-sulfanylethane-1-sulfonate
• CAS Number: 19767-45-4
• Molecular Formula: C2H5NaO3S2
• Molecular Weight: 164.1791
• MDL Number: MFCD00007535
• SMILES: SCCS(=O)(=O)[O-].[Na+]

Computed Properties

• Complexity: 123
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2

Literature

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  Urology 20170201

• Cyclophosphamide-induced Down-Regulation of Uroplakin II in the Mouse Urinary Bladder Epithelium is Prevented by S-Allyl Cysteine.

  Basic & clinical pharmacology & toxicology 20161201

• The cytogenetic action of ifosfamide, mesna, and their combination on peripheral rabbit lymphocytes: an in vivo/in vitro cytogenetic study.

  Cytotechnology 20141001

• Comparision of uroprotective activity of reduced glutathione with mesna in ifosfamide induced hemorrhagic cystitis in rats.

  Indian journal of pharmacology 20140101

• Surface functionalities of gold nanoparticles impact embryonic gene expression responses.

  Nanotoxicology 20130301

• Acrolein and chloroacetaldehyde: an examination of the cell and cell-free biomarkers of toxicity.

  Chemico-biological interactions 20130225

• Treatment of Burkitt lymphoma in equatorial Africa using a simple three-drug combination followed by a salvage regimen for patients with persistent or recurrent disease.

  British journal of haematology 20120901

• Long-term follow-up of patients treated with neoadjuvant chemotherapy and radiotherapy for large, extremity soft tissue sarcomas.

  Cancer 20120801

• Adjuvant chemotherapy decreases and postpones distant metastasis in extremity stage IIB/III synovial sarcoma patients.

  Journal of surgical oncology 20120801

• Mesna-induced photodistributed dermatosis.

  Clinical and experimental dermatology 20120601

• Pharmacological modulation of oxidative stress response in minimally invasive surgery: systematic review.

  Surgical laparoscopy, endoscopy & percutaneous techniques 20120601

• In vitro and in vivo assessment of renal drug transporters in the disposition of mesna and dimesna.

  Journal of clinical pharmacology 20120401

• Coordination of methyl coenzyme M and coenzyme M at divalent and trivalent nickel cyclams: model studies of methyl coenzyme M reductase active site.

  Inorganic chemistry 20120319

• High-dose chemotherapy consolidation for chemosensitive advanced soft tissue sarcoma patients: an open-label, randomized controlled trial.

  Annals of oncology : official journal of the European Society for Medical Oncology 20120301

• Persistent adult zebrafish behavioral deficits results from acute embryonic exposure to gold nanoparticles.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120301

• Successful treatment of ICE-rituximab chemotherapy and subsequent bone marrow transplantation in a patient with early-relapse Burkitt leukemia and inverted duplication of 1q.

  Journal of pediatric hematology/oncology 20120301

• Patterns of chemotherapy-induced toxicities in younger children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee.

  Cancer 20120215

• Interleukin-4 modulates the inflammatory response in ifosfamide-induced hemorrhagic cystitis.

  Inflammation 20120201

• Introduction of sodium pentosan polysulfate and avoidance of urethral catheterisation: improved outcomes in children with haemorrhagic cystitis post stem cell transplant/chemotherapy.

  Journal of pediatric surgery 20120201

• The role of P2X7 purinergic receptors in inflammatory and nociceptive changes accompanying cyclophosphamide-induced haemorrhagic cystitis in mice.

  British journal of pharmacology 20120101

• Low-dose cyclophosphamide associated with hemorrhagic cystitis in a breast cancer patient.

  The breast journal 20120101

• Phase I Study of Topotecan, Ifosfamide, and Etoposide (TIME) with autologous stem cell transplant in refractory cancer: pharmacokinetic and pharmacodynamic correlates.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20111215

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• Separation and recycling of nanoparticles using cloud point extraction with non-ionic surfactant mixtures.

  Journal of colloid and interface science 20111115

• Determination of the sodium 2-mercaptoethanesulfonate based on surface-enhanced Raman scattering.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111015

• Endoscopic submucosal dissection with a flexible Maryland dissector: randomized comparison of mesna and saline solution for submucosal injection (with videos).

  Gastrointestinal endoscopy 20111001

• Fixed drug eruption caused by mesna.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20111001

• Accumulation of BNP7787 in human renal proximal tubule cells.

  Journal of pharmaceutical sciences 20110901

• Intein lacking conserved C-terminal motif G retains controllable N-cleavage activity.

  The FEBS journal 20110901

• Severe allergic reactions to thiol-based cytoprotective agents mesna and amifostine in a child with a supratentorial primitive neuroectodermal tumor.

  Journal of pediatric hematology/oncology 20110801

• Mesna preserves hepatocyte regenerating capacity following liver radiofrequency ablation under Pringle maneuver.

  The Journal of surgical research 20110701

• Mesna, doxorubicin, ifosfamide and dacarbazine chemotherapy for uterine leiomyosarcoma: a report of two cases.

  The journal of obstetrics and gynaecology research 20110601

• 2-Mercaptoethane sulfonate prevents doxorubicin-induced plasma protein oxidation and TNF-α release: implications for the reactive oxygen species-mediated mechanisms of chemobrain.

  Free radical biology & medicine 20110601

• The effect of N-acetylcysteine on the antitumor activity of ifosfamide.

  Canadian journal of physiology and pharmacology 20110501

• Cyclooxygenase-2 contributes to functional changes seen on experimental hemorrhagic cystitis induced by ifosfamide in rat urinary bladder.

  Cancer chemotherapy and pharmacology 20110401

• MESNA (sodium 2-mercaptoethanesulfonate) for prevention of contrast medium-induced nephrotoxicity - controlled trial.

  Clinical nephrology 20110401

• Phase I and pharmacologic study of BNP7787, a novel chemoprotector in patients with advanced non-small cell lung cancer.

  Cancer chemotherapy and pharmacology 20110301

• Two consecutive cases of platinum-refractory pulmonary pleomorphic carcinoma that showed dramatic responses to MAID (mesna, doxorubicin, ifosfamide and dacarbazine) chemotherapy.

  Japanese journal of clinical oncology 20110301

• Short topotecan-based induction regimen in newly diagnosed high-risk neuroblastoma.

  European journal of cancer (Oxford, England : 1990) 20110301

• Chemical inhibitors of methanogenesis and putative applications.

  Applied microbiology and biotechnology 20110301

• Separating nanoparticles from microemulsions.

  Journal of colloid and interface science 20110215

• Structural basis for carbon dioxide binding by 2-ketopropyl coenzyme M oxidoreductase/carboxylase.

  FEBS letters 20110204

• Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of human aminopeptidase N.

  Cancer chemotherapy and pharmacology 20110201

• Preservation of uroplakins by 2-mercaptoethanesulfonate in cyclophosphamide-induced rat cystitis.

  Archives of toxicology 20110101

• Assay of methylotrophic methyltransferases from methanogenic archaea.

  Methods in enzymology 20110101

• Methyl-coenzyme M reductase from Methanothermobacter marburgensis.

  Methods in enzymology 20110101

• 2-oxoacid metabolism in methanogenic CoM and CoB biosynthesis.

  Methods in enzymology 20110101

• [Nephropathy following administration of angiogenesis inhibitors].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101

• [Severe skin reaction with mucous membrane inflammation during MINE chemotherapy].

  Annales de dermatologie et de venereologie 20110101

• Chemoselective protein and peptide immobilization on biosensor surfaces.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Electron transport in acetate-grown Methanosarcina acetivorans.

  BMC microbiology 20110101

• Detection of organometallic and radical intermediates in the catalytic mechanism of methyl-coenzyme M reductase using the natural substrate methyl-coenzyme M and a coenzyme B substrate analogue.

  Biochemistry 20101228

• Effects of the compounds MV8608 and MV8612 obtained from Mandevilla velutina in the model of hemorrhagic cystitis induced by cyclophosphamide in rats.

  Naunyn-Schmiedeberg's archives of pharmacology 20101201

• Shotgun proteomics of Xanthobacter autotrophicus Py2 reveals proteins specific to growth on propylene.

  Archives of microbiology 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Continuously improving ifosfamide/mesna: a winning combination.

  Pediatric blood & cancer 20101001

• Bilateral Wilms' tumors: single-center experience with 22 cases and literature review.

  Urology 20101001

• Structural insight into methyl-coenzyme M reductase chemistry using coenzyme B analogues .

  Biochemistry 20100907

• Long-term outcome of mesna, ifosfamide, mitoxantrone, etoposide (MINE) regimen as a consolidation in patients with aggressive non-Hodgkin lymphoma responding to CHOP.

  Medical oncology (Northwood, London, England) 20100901

• BNP7787-mediated modulation of paclitaxel- and cisplatin-induced aberrant microtubule protein polymerization in vitro.

  Molecular cancer therapeutics 20100901

• Neuroblastoma in an adult: case report.

  Revista medica de Chile 20100901

• Mechanism of inhibition of aliphatic epoxide carboxylation by the coenzyme M analog 2-bromoethanesulfonate.

  The Journal of biological chemistry 20100813

• Chemically assisted submucosal injection facilitates endoscopic submucosal dissection of gastric neoplasms.

  Endoscopy 20100801

• Effect of thiol drugs on tert-butyl hydroperoxide induced luminol chemiluminescence in human erythrocytes, erythrocyte lysate, and erythrocyte membranes.

  Chemico-biological interactions 20100730

• The key nickel enzyme of methanogenesis catalyses the anaerobic oxidation of methane.

  Nature 20100603

• MESNA for chemically assisted tissue dissection.

  Expert opinion on investigational drugs 20100601

• Inhibition of HSV-1 attachment, entry, and cell-to-cell spread by functionalized multivalent gold nanoparticles.

  Small (Weinheim an der Bergstrasse, Germany) 20100507

• Raman characterization of monolayers formed from mixtures of sodium 2-mercaptoethanesulfonate and various aromatic mercapto-derivative bases.

  The journal of physical chemistry. B 20100422

• Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of gamma-glutamyl transpeptidase.

  Cancer chemotherapy and pharmacology 20100401

• Neuroprotective effect of mesna (2-mercaptoethane sulfonate) against spinal cord ischemia/reperfusion injury in rabbits.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20100401

• Docetaxel, ifosfamide and cisplatin in solid tumour treatment: a phase I study.

  Anti-cancer drugs 20100301

• Ambulatory administration of 5-day infusion ifosfamide+mesna: a pilot study in sarcoma patients.

  Cancer chemotherapy and pharmacology 20100201

• Methanogenesis by Methanosarcina acetivorans involves two structurally and functionally distinct classes of heterodisulfide reductase.

  Molecular microbiology 20100201

• Stability of mesna in ReadyMed infusion devices.

  The Annals of pharmacotherapy 20100101

• Incidence and prevention of bladder toxicity from cyclophosphamide in the treatment of rheumatic diseases: a data-driven review.

  Arthritis and rheumatism 20100101

• Successful treatment of metastatic malignant fibrous histiocytoma of the kidney.

  Urologia internationalis 20100101

• Autologous stem cell transplant in a patient with Down syndrome and relapsed Hodgkin lymphoma.

  Pediatric blood & cancer 20091215

• Convergent evolution of coenzyme M biosynthesis in the Methanosarcinales: cysteate synthase evolved from an ancestral threonine synthase.

  The Biochemical journal 20091210

• Immediate type hypersensitivity to chemotherapeutic agents in pediatric patients.

  Asian Pacific journal of allergy and immunology 20091201

• Increased sensitivity of glutathione S-transferase P-null mice to cyclophosphamide-induced urinary bladder toxicity.

  The Journal of pharmacology and experimental therapeutics 20091101

• Diffuse neonatal hemangiomatosis treatment with cyclophosphamide: a case report.

  Journal of pediatric hematology/oncology 20091101

• Inhibition of herpes simplex virus type 1 infection by silver nanoparticles capped with mercaptoethane sulfonate.

  Bioconjugate chemistry 20090819

• Randomized multicenter phase II trial of cisplatin and ifosfamide with or without paclitaxel in recurrent or metastatic carcinoma of the uterine cervix: a Hellenic Cooperative Oncology Group (HeCOG) study.

  Annals of oncology : official journal of the European Society for Medical Oncology 20090801

• Tandem high-dose chemotherapy followed by autologous transplantation in patients with locally advanced or metastatic sarcoma.

  Anticancer research 20090801

• alpha,beta-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases.

  American journal of physiology. Lung cellular and molecular physiology 20090501

• Intraductal administration of a mucolytic agent with gland massages: a suitable conservative treatment of acute obstructive parotitis.

  Southern medical journal 20090501

• Impaired liver regeneration following partial hepatectomy using the Pringle maneuver: Protective effect of mesna.

  Journal of gastroenterology and hepatology 20090401

• Analysis of BNP7787 thiol-disulfide exchange reactions in phosphate buffer and human plasma using microscale electrochemical high performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090401

• Mesna protects splanchnic organs from oxidative stress induced by pneumoperitoneum.

  Surgical endoscopy 20090301

• Chemotherapy for Langerhans cell sarcoma.

  Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20090301

• Determination and applications of the molar absorptivity of phenolic adducts with captopril and mesna.

  Journal of agricultural and food chemistry 20090225

• Undifferentiated sarcoma of the maxillary sinus: report of a rare case in an adult.

  Auris, nasus, larynx 20090201

• Pharmacokinetics of cyclophosphamide and thiotepa in a conventional fractionated high-dose regimen compared with a novel simplified unfractionated regimen.

  Therapeutic drug monitoring 20090201

• Temporary remission of a multirecurrent cystosarcoma phyllodes of the breast by using continuous chemotherapy.

  Plastic and reconstructive surgery 20090201

• Inhibition of human sperm respiration by 4-hydroperoxycyclophosphamide and protection by mesna and WR-1065.

  Fertility and sterility 20090101

• Long-lasting multiagent chemotherapy in adult high-risk Ewing's sarcoma of bone.

  Medical oncology (Northwood, London, England) 20090101

• American Society of Clinical Oncology 2008 clinical practice guideline update: use of chemotherapy and radiation therapy protectants.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090101

• Mesna for the treatment of hyperhomocysteinemia in hemodialysis patients.

  Blood purification 20090101

• Efficient, chemoselective synthesis of immunomicelles using single-domain antibodies with a C-terminal thioester.

  BMC biotechnology 20090101

• Segmental isotopic labeling of proteins for nuclear magnetic resonance.

  Methods in enzymology 20090101

• Effectiveness of a mucolythic agent as a local adjuvant in revision lumbar spine surgery.

  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20081201

• Hepatoblastoma presenting with focal nodular hyperplasia after treatment of neuroblastoma.

  Journal of pediatric surgery 20081201

• Etoposide pharmacokinetics and survival in patients with small cell lung cancer: a multicentre study.

  Lung cancer (Amsterdam, Netherlands) 20081101

• Coordination and binding geometry of methyl-coenzyme M in the red1m state of methyl-coenzyme M reductase.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20081101

• A 50-year-old man with burkitt lymphoma.

  Brain pathology (Zurich, Switzerland) 20081001

• Phase II randomized study of dose-dense docetaxel and cisplatin every 2 weeks with pegfilgrastim and darbepoetin alfa with and without the chemoprotector BNP7787 in patients with advanced non-small cell lung cancer (CALGB 30303).

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20081001

• Characterization of the occurrence of ifosfamide-induced neurotoxicity with concomitant aprepitant.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20080901

• Mesna for treatment of hyperhomocysteinemia in hemodialysis patients: a placebo-controlled, double-blind, randomized trial.

  Clinical journal of the American Society of Nephrology : CJASN 20080701

• Multidisciplinary management of metastatic sarcoma.

  The Surgical clinics of North America 20080601

• In vivo mesna and amifostine do not prevent chloroacetaldehyde nephrotoxicity in vitro.

  Pediatric nephrology (Berlin, Germany) 20080401

• Protection against cisplatin-induced ovarian damage by the antioxidant sodium 2-mercaptoethanesulfonate (mesna) in female rats.

  American journal of obstetrics and gynecology 20080401

• Archaeoglobus infectus sp. nov., a novel thermophilic, chemolithoheterotrophic archaeon isolated from a deep-sea rock collected at Suiyo Seamount, Izu-Bonin Arc, western Pacific Ocean.

  International journal of systematic and evolutionary microbiology 20080401

• Metastatic malignant teratoma arising from mediastinal nonseminomatous germ cell tumor: a case report.

  Military medicine 20080401

• Brainstem primitive neuroectodermal tumors (bstPNET): results of treatment with intensive induction chemotherapy followed by consolidative chemotherapy with autologous hematopoietic cell rescue.

  Pediatric blood & cancer 20080301

• Successful treatment of a child with late-onset T-cell post-transplant lymphoproliferative disorder/lymphoma.

  Pediatric blood & cancer 20080301

• Chemically assisted endoscopic mechanical submucosal dissection by using mesna.

  Gastrointestinal endoscopy 20080301

• Full-dose ifosfamide can be safely administered to outpatients.

  Pediatric blood & cancer 20080201

• Intensive chemotherapy followed by consolidative myeloablative chemotherapy with autologous hematopoietic cell rescue (AuHCR) in young children with newly diagnosed supratentorial primitive neuroectodermal tumors (sPNETs): report of the Head Start I and II experience.

  Pediatric blood & cancer 20080201

• Prophylaxis with mesna prevents oxidative stress induced by ischemia reperfusion in the intestine via inhibition of nuclear factor-kappaB activation.

  Journal of gastroenterology and hepatology 20080201

• Cytotoxic 3,5-bis(benzylidene)piperidin-4-ones and N-acyl analogs displaying selective toxicity for malignant cells.

  European journal of medicinal chemistry 20080101

• Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats.

  Journal of cancer research and clinical oncology 20080101

• Off-label use of MESNA in Dupuytren's disease.

  Medical hypotheses 20080101

• Amplification of molecular information through self-assembly: nanofibers formed from amino acids and cyanine dyes by extended molecular pairing.

  Angewandte Chemie (International ed. in English) 20080101

• Mediastinal sarcoma with deviated tracheal anatomy.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080101

• Langerhans cell sarcoma emanating from the upper arm skin: successful treatment by MAID regimen.

  Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20080101

• Stage IV primitive-appearing sinus and orbital rhabdomyosarcoma presenting in a 68-year-old female previously treated for breast cancer.

  Orbit (Amsterdam, Netherlands) 20080101

• Protein-cross-linked polymeric materials through site-selective bioconjugation.

  Angewandte Chemie (International ed. in English) 20080101

• Intravenous cyclophosphamide in patients with chronic systemic inflammatory diseases: morbidity and mortality.

  Scandinavian journal of rheumatology 20080101

• Hysteroscopic resection of uterine leiomyosarcoma: a case report and literature review.

  Journal of minimally invasive gynecology 20080101

• One-step refolding and purification of disulfide-containing proteins with a C-terminal MESNA thioester.

  BMC biotechnology 20080101

• [Responses of 109 adult soft tissue sarcoma patients to chemotherapy].

  Ai zheng = Aizheng = Chinese journal of cancer 20071201

• A gynecologic oncology group randomized phase III trial of whole abdominal irradiation (WAI) vs. cisplatin-ifosfamide and mesna (CIM) as post-surgical therapy in stage I-IV carcinosarcoma (CS) of the uterus.

  Gynecologic oncology 20071101

• The effects of viscero-somatic interactions on thalamic mast cell recruitment in cystitic rats.

  Journal of neuroimmunology 20071001

• Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide.

  Pediatric blood & cancer 20070901

• Pathophysiological aspects of cyclophosphamide and ifosfamide induced hemorrhagic cystitis; implication of reactive oxygen and nitrogen species as well as PARP activation.

  Cell biology and toxicology 20070901

• Tandem high-dose chemotherapy with autologous peripheral hematopoietic progenitor cell rescue as consolidation therapy for patients with high-risk Ewing family tumors.

  Pediatric blood & cancer 20070801

• Expressed protein ligation using an N-terminal cysteine containing fragment generated in vivo from a pelB fusion protein.

  Protein expression and purification 20070801

• Mesna as a nonvitamin intervention to lower plasma total homocysteine concentration: implications for assessment of the homocysteine theory of atherosclerosis.

  Journal of clinical pharmacology 20070801

• Cytoprotective agents used in the treatment of patients with cancer.

  Seminars in oncology nursing 20070801

• The effect of short-term intensive chemotherapy on reactivation of tuberculosis.

  Annals of oncology : official journal of the European Society for Medical Oncology 20070701

• Mesna or cysteine prevents chloroacetaldehyde-induced cell death of human proximal tubule cells.

  Pediatric nephrology (Berlin, Germany) 20070601

• A pilot study of cisplatin, ifosfamide and mesna in the treatment of malignant mixed mesodermal tumors of the ovary.

  Gynecologic oncology 20070501

• Histological changes in bladders of patients submitted to ifosfamide chemotherapy even with mesna prophylaxis.

  Cancer chemotherapy and pharmacology 20070401

• Ifosfamide toxicity in cultured proximal renal tubule cells.

  Pediatric nephrology (Berlin, Germany) 20070301

• Synovial cell sarcoma of the vulva: multimodality treatment incorporating preoperative external-beam radiation, hemivulvectomy, flap reconstruction, interstitial brachytherapy, and chemotherapy.

  Gynecologic oncology 20070101

• The effect of mesna on plasma total homocysteine concentration in hemodialysis patients.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20070101

• [Study on interaction of acetaldehyde with thioalcohols by infrared spectroscopy].

  Biomeditsinskaia khimiia 20070101

• Ifosfamide metabolites CAA, 4-OH-Ifo and Ifo-mustard reduce apical phosphate transport by changing NaPi-IIa in OK cells.

  Kidney international 20061101

• A model of hemorrhagic cystitis induced with acrolein in mice.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20061101

• [Malignant fibrous histiocytoma of the retroperitoneum--review of clinical course and histopathology].

  Hinyokika kiyo. Acta urologica Japonica 20061001

• Mesna protects intestinal mucosa from ischemia/reperfusion injury.

  The Journal of surgical research 20060801

• Myxoid liposarcoma metastatic to the thyroid gland: a case report and literature review.

  The Journal of laryngology and otology 20060601

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Evidence of a new dechlorinated ochratoxin A derivative formed in opossum kidney cell cultures after pretreatment by modulators of glutathione pathways: correlation with DNA-adduct formation.

  Molecular nutrition & food research 20060501

• Successful treatment via chemotherapy and surgical resection of a femoral hemangiopericytoma with pulmonary metastasis.

  Journal of pediatric hematology/oncology 20060401

• [A case of secondary malignant lymphoma of the urinary bladder].

  Hinyokika kiyo. Acta urologica Japonica 20060401

• Results of a phase II clinical trial on the use of ifosfamide for treatment of cats with vaccine-associated sarcomas.

  American journal of veterinary research 20060301

• Preoperative chemotherapy and split-course radiation therapy for patients with localized soft tissue sarcomas: home run, base hit, or strike out?

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060201

• Phase II study of neoadjuvant chemotherapy and radiation therapy in the management of high-risk, high-grade, soft tissue sarcomas of the extremities and body wall: Radiation Therapy Oncology Group Trial 9514.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060201

• Ifosfamide/mesna as salvage therapy in platinum pretreated ovarian cancer patients--long-term results of a phase II study.

  Cancer investigation 20060201

• [Risk factors and treatment of hemorrhagic cystitis in children after hematopoietic stem cell transplantation].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20060201

• Practical use of MESNA in atelectatic ears and adhesive otitis media.

  ORL; journal for oto-rhino-laryngology and its related specialties 20060101

• Spinal epidural extraskeletal Ewing sarcoma in an adolescent boy: a case report.

  Pediatric hematology and oncology 20060101

• Adjuvant treatment of high-risk adult soft tissue sarcomas: a survey by the Italian Sarcoma Group.

  Tumori 20060101

• Comparison of uroprotective efficacy of mesna and amifostine in Cyclophosphamide- induced hemorrhagic cystitis in rats.

  Indian journal of cancer 20060101

• Retroperitoneal synovial sarcoma.

  Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 20060101

• High-dose cyclophosphamide and MESNA infusion can cause acute atrial fibrillation.

  American journal of hematology 20051101

• Evidence for a metal-thiolate intermediate in alkyl group transfer from epoxypropane to coenzyme M and cooperative metal ion binding in epoxyalkane:CoM transferase.

  Biochemistry 20051004

• Glucocorticoids acutely increase cell surface Na+/H+ exchanger-3 (NHE3) by activation of NHE3 exocytosis.

  American journal of physiology. Renal physiology 20051001

• Primary angiosarcoma of the ovary: a case report of Stage I disease.

  Gynecologic oncology 20051001

• Primitive neuroectodermal tumor of the cervix uteri: a case report -- changing concepts in therapy.

  Gynecologic oncology 20050901

• Alveolar soft part sarcoma: a rare and enigmatic entity.

  Clinical orthopaedics and related research 20050901

• In vivo generation of angiostatin isoforms by administration of a plasminogen activator and a free sulfhydryl donor: a phase I study of an angiostatic cocktail of tissue plasminogen activator and mesna.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050901

• Contribution of flavonoid antioxidants to the preventive effect of mesna in cyclophosphamide-induced cystitis in rats.

  Archives of toxicology 20050801

• The role of preoperative radiotherapy in nonmetastatic high-grade osteosarcoma of the extremities for limb-sparing surgery.

  International journal of radiation oncology, biology, physics 20050701

• Acetaminophen-induced anion gap metabolic acidosis and 5-oxoprolinuria (pyroglutamic aciduria) acquired in hospital.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20050701

• Phase II trial of neoadjuvant vincristine, ifosfamide, and doxorubicin with granulocyte colony-stimulating factor support in children and adolescents with advanced-stage nonrhabdomyosarcomatous soft tissue sarcomas: a Pediatric Oncology Group Study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050620

• Temperature dependence of methyl-coenzyme M reductase activity and of the formation of the methyl-coenzyme M reductase red2 state induced by coenzyme B.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20050601

• Phase I and pharmacokinetic study of the novel chemoprotector BNP7787 in combination with cisplatin and attempt to eliminate the hydration schedule.

  British journal of cancer 20050509

• Doxorubicin-induced second degree and complete atrioventricular block.

  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20050501

• A phase I study of prolonged ambulatory infusion of Ifosfamide with oral mesna.

  Chemotherapy 20050501

• Re: Comments on paper by Son et al.

  Toxicology letters 20050410

• Long-term results of dose density therapy in patients with aggressive lymphoma.

  Annals of hematology 20050401

• A rare case of breast sarcoma brain metastases.

  Journal of neuro-oncology 20050401

• Direct interaction of coenzyme M with the active-site Fe-S cluster of heterodisulfide reductase.

  FEBS letters 20050314

• Photoactivated luminescent CdSe quantum dots as sensitive cyanide probes in aqueous solutions.

  Chemical communications (Cambridge, England) 20050221

• Effect of the electrostatic interaction on the redox reaction of positively charged cytochrome C adsorbed on the negatively charged surfaces of acid-terminated alkanethiol monolayers on a Au(111) electrode.

  Langmuir : the ACS journal of surfaces and colloids 20050215

• Attenuation of bleomycin-induced lung fibrosis in rats by mesna.

  European journal of pharmacology 20050210

• Biological chemistry of naturally occurring thiols of microbial and marine origin.

  Journal of natural products 20050201

• Panniculitis induced by a chemotherapy regimen consisting of topotecan and cyclophosphamide.

  Pediatric blood & cancer 20050101

• High performance liquid chromatography analysis of MESNA (2-mercaptoethane sulfonate) in biological samples using fluorescence detection.

  Biomedical chromatography : BMC 20050101

• Protective effects of MESNA (2-mercaptoethane sulphonate) against acetaminophen-induced hepatorenal oxidative damage in mice.

  Journal of applied toxicology : JAT 20050101

• Protective effect of MESNA (2-mercaptoethane sulfonate) against hepatic ischemia/reperfusion injury in rats.

  Surgery today 20050101

• Doxorubicin and ifosfamide-mesna in advanced and recurrent uterine sarcomas.

  European journal of gynaecological oncology 20050101

• Uterine liposarcoma in a young woman: a case report.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20050101

• Feasibility and response to induction chemotherapy intensified with high-dose methotrexate for young children with newly diagnosed high-risk disseminated medulloblastoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041215

• Aggressive mixed epithelial-stromal tumour of the kidney treated with chemotherapy and radiotherapy.

  The Lancet. Oncology 20041201

• High-dose ifosfamide with hematopoietic growth factor support in advanced bone and soft tissue sarcomas.

  Experimental oncology 20041201

• Effects of ursolic acid, betulin and sulfur-containing compounds on mucin release from airway goblet cells.

  Planta medica 20041201

• Contribution of antioxidants to preventive effect of mesna in cyclophosphamide-induced hemorrhagic cystitis in rats.

  Cancer chemotherapy and pharmacology 20041101

• Neo-adjuvant chemotherapy for primary high-grade extremity soft tissue sarcoma.

  Annals of oncology : official journal of the European Society for Medical Oncology 20041101

• Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs.

  Radiation research 20041101

• Urinary bladder cancer in Wegener's granulomatosis: is it more than cyclophosphamide?

  Annals of the rheumatic diseases 20041001

• Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse.

  Pediatric blood & cancer 20041001

• Mesna (2-mercaptoethane sulfonate) prevents ischemia/reperfusion induced renal oxidative damage in rats.

  Life sciences 20040924

• Urine mesna excretion after intravenous and oral dosing in ifosfamide-treated children.

  Cancer chemotherapy and pharmacology 20040901

• 2-Mercaptoethane sulfonate (MESNA) protects against burn-induced renal injury in rats.

  Burns : journal of the International Society for Burn Injuries 20040901

• Mesna ameliorates intestinal mucosa damage after ifosfamide administration in the rabbit at a dose-related manner.

  The Journal of surgical research 20040901

• Probing the reactivity of Ni in the active site of methyl-coenzyme M reductase with substrate analogues.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20040901

• [Soft tissue sarcoma: postoperative chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20040901

• Possible (enzymatic) routes and biological sites for metabolic reduction of BNP7787, a new protector against cisplatin-induced side-effects.

  Biochemical pharmacology 20040801

• Hyperbaric oxygen therapy for cyclophosphamide induced refractory hemorrhagic cystitis in a child.

  The Journal of urology 20040801

• Extraskeletal Ewing sarcoma of the diaphragm presenting with hemothorax.

  The Annals of thoracic surgery 20040801

• The stereoselectivity and catalytic properties of Xanthobacter autotrophicus 2-[(R)-2-Hydroxypropylthio]ethanesulfonate dehydrogenase are controlled by interactions between C-terminal arginine residues and the sulfonate of coenzyme M.

  Biochemistry 20040601

• Pharmacokinetic behaviour of the chemoprotectants BNP7787 and mesna after an i.v. bolus injection in rats.

  British journal of cancer 20040419

• Alveolar soft-part sarcoma responsive to intensive chemotherapy.

  Journal of pediatric hematology/oncology 20040401

• Modified magrath regimens for adults with Burkitt and Burkitt-like lymphomas: preserved efficacy with decreased toxicity.

  Leukemia & lymphoma 20040401

• Primary omental synovial sarcoma: a case with cytogenetic confirmation.

  Pathology 20040401

• Extended total sacrectomy and reconstruction for sacral tumor.

  Spine 20040315

• Ternatin, a flavonoid, prevents cyclophosphamide and ifosfamide-induced hemorrhagic cystitis in rats.

  Phytotherapy research : PTR 20040201

• BNP-7787 (BioNumerik/Baxter Oncology/Grelan).

  IDrugs : the investigational drugs journal 20040101

• Camptothecin analogs (irinotecan or topotecan) plus high-dose cyclophosphamide as preparative regimens for antibody-based immunotherapy in resistant neuroblastoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040101

• Influence of mesna on the pharmacokinetics of cisplatin and carboplatin in pediatric cancer patients.

  Medical oncology (Northwood, London, England) 20040101

• The effect of cytoprotective agents in platinum anticancer therapy.

  Metal ions in biological systems 20040101

• Free reactive oxygen species and nephrotoxicity of contrast agents.

  Kidney & blood pressure research 20040101

• Angiogenesis inhibition by angiostatin, endostatin and TNP-470 prevents cyclophosphamide induced cystitis.

  Angiogenesis 20040101

• [Financial assessment of device for the preparation of intravenous mixtures in hospital pharmacy].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20040101

• Ifosfamide, mesna, and interferon-alpha2A combination chemoimmunotherapy in malignant mesothelioma: results of a single center in central anatolia.

  Medical oncology (Northwood, London, England) 20040101

• Pharmacokinetics and pharmacodynamics of mesna-mediated plasma cysteine depletion.

  Journal of clinical pharmacology 20031201

• Stability of cyclophosphamide and mesna admixtures in polyethylene infusion bags.

  The Annals of pharmacotherapy 20031201

• Crossover randomized comparison of intravenous versus intravenous/oral mesna in soft tissue sarcoma treated with high-dose ifosfamide.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20031201

• A pilot study of CODOX-M/IVAC in primary refractory or relapsed high-grade non-Hodgkin's lymphoma. A Scotland and Newcastle Lymphoma Group Study.

  Haematologica 20031201

• Two schedules of application for mesna and their influence on the thiol-metabolism.

  International journal of clinical pharmacology and therapeutics 20031201

• The structural determination of phosphosulfolactate synthase from Methanococcus jannaschii at 1.7-A resolution: an enolase that is not an enolase.

  The Journal of biological chemistry 20031114

• Multivariate analysis of risk factors for hemorrhagic cystitis after hematopoietic stem cell transplantation.

  Bone marrow transplantation 20031101

• Use of dexamethasone with mesna for the prevention of ifosfamide-induced hemorrhagic cystitis.

  International journal of urology : official journal of the Japanese Urological Association 20031101

• Chemically assisted capsulectomy in the rabbit model: a new approach.

  Plastic and reconstructive surgery 20031001

• The effectiveness of sodium 2-mercaptoethane sulfonate (mesna) in reducing capsular formation around implants in a rabbit model.

  Plastic and reconstructive surgery 20031001

• Pelvic primitive neuroectodermal tumor associated with a cluster of small round cell tumors: case report and review of current literature.

  Gynecologic oncology 20031001

• Outcome after hyperbaric oxygen treatment for cyclophosphamide-induced refractory hemorrhagic cystitis.

  The Journal of urology 20030901

• A phase II trial of cisplatin, ifosfamide, and mesna in patients with advanced or recurrent uterine malignant mixed müllerian tumors with evaluation of potential molecular targets.

  Gynecologic oncology 20030901

• Comparative toxicity of ifosfamide metabolites and protective effect of mesna and amifostine in cultured renal tubule cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20030801

• Single center experience of a new intensive induction therapy for ewing's family of tumors: feasibility, toxicity, and stem cell mobilization properties.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030801

• Pharmacokinetics and preliminary clinical data of the novel chemoprotectant BNP7787 and cisplatin and their metabolites.

  Clinical pharmacology and therapeutics 20030801

• Biocatalytic conversion of epoxides.

  Current opinion in biotechnology 20030801

• Has 'MAID' made it in the management of high-risk soft-tissue sarcoma?

  International journal of radiation oncology, biology, physics 20030715

• Neoadjuvant chemotherapy and radiotherapy for large extremity soft-tissue sarcomas.

  International journal of radiation oncology, biology, physics 20030715

• High-dose ifosfamide with mesna and granulocyte-colony-stimulating factor (recombinant human G-CSF) in patients with unresectable malignant mesothelioma.

  Cancer 20030715

• Inactivation of acrolein by sodium 2-mercaptoethanesulfonate using headspace-solid-phase microextraction gas chromatography and mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030705

• Catalysis by methyl-coenzyme M reductase: a theoretical study for heterodisulfide product formation.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20030701

• New approaches to drug discovery and development: a mechanism-based approach to pharmaceutical research and its application to BNP7787, a novel chemoprotective agent.

  Cancer chemotherapy and pharmacology 20030701

• The chemical reactivity of BNP7787 and its metabolite mesna with the cytostatic agent cisplatin: comparison with the nucleophiles thiosulfate, DDTC, glutathione and its disulfide GSSG.

  Cancer chemotherapy and pharmacology 20030601

• Vibrational spectroscopic studies of mesna and dimesna.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030601

• Pharmacokinetics of BNP7787 and its metabolite mesna in plasma and ascites: a case report.

  Cancer chemotherapy and pharmacology 20030601

• Effect of the antioxidant Mesna (2-mercaptoethane sulfonate) on experimental colitis.

  Digestive diseases and sciences 20030601

• Nickel uptake and utilization by microorganisms.

  FEMS microbiology reviews 20030601

• Modulation of plasma thiols and mixed disulfides by BNP7787 in patients receiving paclitaxel/cisplatin therapy.

  Cancer chemotherapy and pharmacology 20030501

• Simultaneous determination of BNP7787 and its metabolite mesna in plasma and tissue by micro-HPLC with a dual electrochemical detector.

  Journal of pharmaceutical sciences 20030501

• Chemically assisted dissection of tissues in laparoscopic excision of endometriotic cysts.

  The Journal of the American Association of Gynecologic Laparoscopists 20030501

• New chemotherapy agents in veterinary medicine.

  The Veterinary clinics of North America. Small animal practice 20030501

• Coenzyme B induced coordination of coenzyme M via its thiol group to Ni(I) of F430 in active methyl-coenzyme M reductase.

  Journal of the American Chemical Society 20030430

• Lack of effects of sodium 2-mercaptoethane sulfonate (mesna) on Ochratoxin A induced renal tumorigenicity following life-time oral administration of Ochratoxin A in DA and Lewis rats.

  Toxicology letters 20030430

• Inhibitory effects of 2-mercaptoethane sulfonate and 6-phenylhexyl isothiocyanate on urinary bladder tumorigenesis in rats induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.

  Cancer letters 20030410

• Redox potentials of methanophenazine and CoB-S-S-CoM, factors involved in electron transport in Methanogenic archaea.

  Chembiochem : a European journal of chemical biology 20030404

• Phase II study of induction chemotherapy with paclitaxel, ifosfamide, and carboplatin (TIC) for patients with locally advanced squamous cell carcinoma of the head and neck.

  Cancer 20030315

• Coenzyme M binds to a [4Fe-4S] cluster in the active site of heterodisulfide reductase as deduced from EPR studies with the [33S]coenzyme M-treated enzyme.

  FEBS letters 20030313

• High survival rate in childhood non-Hodgkin lymphoma without CNS involvement: results of BFM 95 study in Kuwait.

  Pediatric hematology and oncology 20030301

• Occupational airborne allergic contact dermatitis from mesna.

  Contact dermatitis 20030301

• Quantification of mesna and total mesna in kidney tissue by high-performance liquid chromatography with electrochemical detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030105

• Bioenergetics of the formyl-methanofuran dehydrogenase and heterodisulfide reductase reactions in Methanothermobacter thermautotrophicus.

  European journal of biochemistry 20030101

• Aliphatic epoxide carboxylation.

  Annual review of biochemistry 20030101

• Expression of CD40 has no predictive value in soft tissue sarcomas.

  Anticancer research 20030101

• Dose finding of ifosfamide administered with a chronic two-week continuous infusion.

  Oncology 20030101

• Effects of subchronic ifosfamide-mesna treatment on testes and semen characteristics in the rabbit.

  Reproductive toxicology (Elmsford, N.Y.) 20030101

• Intensive sequential dose dense chemotherapy with stem cell support as first-line treatment in advanced ovarian carcinoma: a phase II study.

  Bone marrow transplantation 20021201

• Structural basis for CO2 fixation by a novel member of the disulfide oxidoreductase family of enzymes, 2-ketopropyl-coenzyme M oxidoreductase/carboxylase.

  Biochemistry 20021029

• Ifosfamide-induced encephalopathy.

  Southern medical journal 20021001

• Outpatient intensive chemotherapy for small cell lung cancer: five years experience of modified 'ICE' ifosfamide carboplatin and etoposide.

  Clinical oncology (Royal College of Radiologists (Great Britain)) 20021001

• Peripheral blood stem cell support reduces the toxicity of intensive chemotherapy for children and adolescents with metastatic sarcomas.

  Cancer 20020915

• Abdominal aortic sarcoma: report of a case with long-term survival and review of the literature.

  Annals of vascular surgery 20020901

• Outcome of B-cell non-Hodgkin lymphoma protocol CCCG-B NHL97: a report from Chinese multi-center cooperative group.

  Medical and pediatric oncology 20020901

• Mitoxantrone/ifosfamide/etoposide salvage regimen with rituximab for in vivo purging in patients with relapsed lymphoma.

  Clinical lymphoma 20020901

• Kinetic analysis of the reactions of 4-hydroperoxycyclophosphamide and acrolein with glutathione, mesna, and WR-1065.

  Drug metabolism and disposition: the biological fate of chemicals 20020801

• Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms.

  Nature immunology 20020801

• [Preliminary result of advanced soft tissue sarcoma treated by MAID regimen].

  Ai zheng = Aizheng = Chinese journal of cancer 20020801

• Phase II study of induction chemotherapy with paclitaxel, ifosfamide, and carboplatin (TIC) for patients with locally advanced squamous cell carcinoma of the head and neck.

  Cancer 20020715

• 2002 update of recommendations for the use of chemotherapy and radiotherapy protectants: clinical practice guidelines of the American Society of Clinical Oncology.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020615

• BNP7787, a novel protector against platinum-related toxicities, does not affect the efficacy of cisplatin or carboplatin in human tumour xenografts.

  European journal of cancer (Oxford, England : 1990) 20020501

• Gemcitabine, ifosfamide and Navelbine (GIN): a platinum-free combination in advanced non-small-cell lung cancer (NSCLC).

  Cancer chemotherapy and pharmacology 20020501

• Polysulfonates derived from metal thiolate complexes as inhibitors of HIV-1 and various other enveloped viruses in vitro.

  Antiviral chemistry & chemotherapy 20020501

• Identification of coenzyme M biosynthetic phosphosulfolactate synthase: a new family of sulfonate-biosynthesizing enzymes.

  The Journal of biological chemistry 20020419

• Kinetic and microcalorimetric analysis of substrate and cofactor interactions in epoxyalkane:CoM transferase, a zinc-dependent epoxidase.

  Biochemistry 20020416

• The role of zinc in the methylation of the coenzyme M thiol group in methanol:coenzyme M methyltransferase from Methanosarcina barkeri.

  European journal of biochemistry 20020401

• Elucidation of methanogenic coenzyme biosyntheses: from spectroscopy to genomics.

  Natural product reports 20020401

• Influence of mucolytic therapy on respiratory mechanics in patients with chronic obstructive pulmonary disease.

  European journal of medical research 20020328

• Intravenous pulse administration of cyclophosphamide is an effective and safe treatment for sensitized cardiac allograft recipients.

  Circulation 20020312

• Ifosfamide and vinorelbine in advanced platinum-resistant ovarian cancer: excessive toxicity with a potentially active regimen.

  Gynecologic oncology 20020301

• Heterodisulfide reductase from Methanothermobacter marburgensis contains an active-site [4Fe-4S] cluster that is directly involved in mediating heterodisulfide reduction.

  FEBS letters 20020213

• Chemotherapy, irradiation, and surgery for function-preserving therapy of primary extremity soft tissue sarcomas: initial treatment with ifosfamide, mitomycin, doxorubicin, and cisplatin plus granulocyte macrophage-colony-stimulating factor.

  Cancer 20020201

• The nickel enzyme methyl-coenzyme M reductase from methanogenic archaea: in vitro interconversions among the EPR detectable MCR-red1 and MCR-red2 states.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20020101

• Cyclophosphamide and the urinary tract.

  Internal medicine journal 20020101

• Ewing's sarcoma of the mandible: a combined approach to treatment.

  The Journal of clinical pediatric dentistry 20020101

• U.S. Food and Drug Administration drug approval summaries: imatinib mesylate, mesna tablets, and zoledronic acid.

  The oncologist 20020101

• Recombinant human interleukin-3 administered concomitantly with chemotherapy in patients with relapsed small cell lung cancer.

  Journal of experimental therapeutics & oncology 20020101

• Mesna, doxorubicin, ifosfamide, and dacarbazine (MAID) chemotherapy for gynecological sarcomas.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20020101

• Radioprotectants: current status and new directions.

  Oncology 20020101

• Blood thiols following amifostine and mesna infusions, a pediatric oncology group study.

  Drug metabolism and disposition: the biological fate of chemicals 20011101

• Zinc-thiolate intermediate in catalysis of methyl group transfer in Methanosarcina barkeri.

  Biochemistry 20011030

• Identification of coenzyme M biosynthetic 2-phosphosulfolactate phosphatase. A member of a new class of Mg(2+)-dependent acid phosphatases.

  European journal of biochemistry 20011001

• [Combination chemotherapy with VP-16 in the treatment of lung cancer and malignant lymphoma].

  Gan to kagaku ryoho. Cancer & chemotherapy 20011001

• Postchemotherapy confusion.

  Oncology nursing forum 20011001

• Ifosfamide, paclitaxel and cisplatin first-line chemotherapy in advanced, suboptimally debulked epithelial ovarian cancer.

  Cancer 20011001

• Cystine analyses of separate day and night urine as a basis for the management of patients with homozygous cystinuria.

  Urological research 20011001

• Prevention of further cyclophosphamide induced hemorrhagic cystitis by hyperbaric oxygen and mesna in guinea pigs.

  The Journal of urology 20010901

• Serum creatine kinase levels parallel the clinical course for rhabdomyomatous Wilms tumor.

  American journal of clinical pathology 20010901

• Anticipated administration of GM-CSF in the treatment of non small cell lung cancer.

  Journal of experimental & clinical cancer research : CR 20010901

• Effect of mesna on lethal effect and hematological toxicity of taxol and vepeside in mice.

  Bulletin of experimental biology and medicine 20010901

• The management of intractable haematuria.

  BJU international 20010801

• Radiation therapy after a partial response to CHOP chemotherapy for aggressive lymphomas.

  International journal of radiation oncology, biology, physics 20010701

• Intein-mediated ligation and cyclization of expressed proteins.

  Methods (San Diego, Calif.) 20010701

• Ifosfamide- and etoposide-based chemotherapy as salvage and mobilizing regimens for poor prognosis lymphoma.

  European journal of haematology. Supplementum 20010701

• DICE (dexamethasone, ifosfamide, cisplatin, etoposide) infusional chemotherapy for refractory or relapsed non-Hodgkin's lymphoma (NHL).

  European journal of haematology. Supplementum 20010701

• [Treatment of vasculitis with antineutrophil cytoplasmic autoantibodies (ACPN)].

  Presse medicale (Paris, France : 1983) 20010630

• Combination chemotherapy for extensive small cell lung cancer -- experience from India.

  Lung cancer (Amsterdam, Netherlands) 20010501

• Superiority of high-dose platinum (cisplatin and carboplatin) compared to carboplatin alone in combination chemotherapy for small-cell lung carcinoma: a prospective randomised trial of 280 consecutive patients.

  Annals of oncology : official journal of the European Society for Medical Oncology 20010501

• Secondary thyroid carcinoma after treatment for clear cell carcinoma of the uterus: case report and review of the literature.

  Journal of pediatric hematology/oncology 20010501

• Facile and sensitive method for the determination of mesna in plasma by high-performance liquid chromatography with ultraviolet detection.

  Journal of chromatography. A 20010420

• Quantification of BNP7787 (dimesna) and its metabolite mesna in human plasma and urine by high-performance liquid chromatography with electrochemical detection.

  Journal of chromatography. B, Biomedical sciences and applications 20010405

• [Post-operative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medulloblastoma in childhood: results of German prospective randomised trial HIT'91].

  Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20010401

• Crystallization and preliminary X-ray analysis of a NADPH 2-ketopropyl-coenzyme M oxidoreductase/carboxylase.

  Acta crystallographica. Section D, Biological crystallography 20010301

• Adjuvant chemotherapy for adult soft tissue sarcomas of the extremities and girdles: results of the Italian randomized cooperative trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010301

• Mesna: a novel renoprotective antioxidant in ischaemic acute renal failure.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010301

• Immunoglobulin D myeloma presenting as an extraosseous soft tissue tumor.

  Skeletal radiology 20010301

• Characterization of a naturally occurring trans-splicing intein from Synechocystis sp. PCC6803.

  Biochemistry 20010206

• Use of hematopoietic progenitors in whole blood to support dose-dense chemotherapy: a randomized phase II trial in small-cell lung cancer patients.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010201

• [Is it useful to perform a (67)gallium scintigraphy in the follow-up of patients with gastric lymphoma?].

  Revista espanola de medicina nuclear 20010201

• Treatment of mandibular malignant fibrous histiocytoma during pregnancy.

  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20010201

• Sustained response of sarcomatoid renal-cell carcinoma to MAID chemotherapy: case report and review of the literature.

  Annals of oncology : official journal of the European Society for Medical Oncology 20010201

• [Recommendations of the Working Group 'Supportive Massnahmen in der Onkologie' concerning the Clinical Use of Cytoprotectives].

  Onkologie 20010201

• Characterization of the intramolecular electron transfer pathway from 2-hydroxyphenazine to the heterodisulfide reductase from Methanosarcina thermophila.

  The Journal of biological chemistry 20010126

• Biosynthesis of the methanogenic cofactors.

  Vitamins and hormones 20010101

• Variation in administration of cyclophosphamide and mesna in the treatment of childhood malignancies.

  Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses 20010101

• The kinetics and mechanisms of the reaction of Mesna with cisplatin, oxiplatin and carboplatin.

  Anticancer research 20010101

• [Development of cancer chemotherapy. Cytoprotective agents].

  La Clinica terapeutica 20010101

• [Hemorrhagic cystitis related to the high-dose conditioning therapy in a bone marrow recipient].

  Przeglad lekarski 20010101

• Novel thiols of prokaryotes.

  Annual review of microbiology 20010101

• [Malignant Brenner tumor and transitional cell ovarian carcinoma--description of two cases].

  Akusherstvo i ginekologiia 20010101

• Methyl-coenzyme M formation in methanogenic archaea. Involvement of zinc in coenzyme M activation.

  European journal of biochemistry 20000501

• Pharmacological and histopathological study of cyclophosphamide-induced hemorrhagic cystitis - comparison of the effects of dexamethasone and Mesna.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 19991001

• A role for coenzyme M (2-mercaptoethanesulfonic acid) in a bacterial pathway of aliphatic epoxide carboxylation.

  Proceedings of the National Academy of Sciences of the United States of America 19990720

• Prevention of cyclophosphamide-induced hemorrhagic cystitis by glucose-mannose binding plant lectins.

  The Journal of urology 19990601

• The uroprotection of mesna on cyclophosphamide cystitis in rats. Its consequences on behaviour and brain activities.

  Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie 19990601

• Peripheral blood progenitor cell mobilisation in patients with multiple myeloma following oral idarubicin and dexamethasone (Z-Dex) induction therapy.

  Leukemia 19971201

• Crystal structure of methyl-coenzyme M reductase: the key enzyme of biological methane formation.

  Science (New York, N.Y.) 19971121

• Urinary proton magnetic resonance studies of early ifosfamide-induced nephrotoxicity and encephalopathy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 19970901

• Influence of mesna on urotoxic effects of selected bromosubstituted analogs of ifosfamide.

  Archivum immunologiae et therapiae experimentalis 19970101

• Combined intravenous and oral mesna in outpatients treated with ifosfamide.

  Cancer chemotherapy and pharmacology 19970101

• Ifosfamide and vinorelbine as first-line chemotherapy for advanced non-small cell lung carcinoma.

  American journal of clinical oncology 19961201

• Ifosfamide encephalopathy and methylene-blue: a case report.

  Annals of oncology : official journal of the European Society for Medical Oncology 19960801

• Continuous subcutaneous administration of mesna to prevent ifosfamide-induced hemorrhagic cystitis.

  Seminars in oncology 19960601

• [The prevention of hemorrhagic cystitis during the performance of bone marrow and peripheral blood stem cell transplantation in the hematologic cancer clinic].

  Terapevticheskii arkhiv 19960101

• Evaluation of ifosfamide plus mesna as first-line chemotherapy in women with metastatic breast cancer.

  American journal of clinical oncology 19951201

• High-dose ifosfamide: circumvention of resistance to standard-dose ifosfamide in advanced soft tissue sarcomas.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19950701

• [Ifosfamide-induced hemorrhagic cystitis and its prevention by mesna].

  Gan to kagaku ryoho. Cancer & chemotherapy 19950601

• Ambulatory 4-day continuous-infusion schedule of high-dose ifosfamide with mesna uroprotection and granulocyte colony-stimulating factor in advanced solid tumours: a phase I study.

  Annals of oncology : official journal of the European Society for Medical Oncology 19950201

• Cyclophosphamide (3.6 g/m2) therapy with G-CSF support for resistant myeloma.

  Haematologica 19940101

• [Epileptic seizures and treatment with ifosfamide-mesna].

  Revue neurologique 19940101

• Single-agent ifosfamide studies in sarcomas of soft tissue and bone: the M.D. Anderson experience.

  Cancer chemotherapy and pharmacology 19930101

• Ifosfamide combination regimens for soft-tissue sarcoma.

  Cancer chemotherapy and pharmacology 19930101

• Ifosfamide in the treatment of soft-tissue sarcomas: experience at the West German Tumor Center, Essen.

  Cancer chemotherapy and pharmacology 19930101

• Urinary bladder cancer following cyclophosphamide therapy for Hodgkin's disease.

  Leukemia & lymphoma 19921201

• Oral ifosfamide-mesna: a clinical investigation in advanced non-small-cell lung cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 19921101

• Encephalopathy in ifosfamide-treated patients.

  Acta neurologica Scandinavica 19921101

• An extended phase II trial of ifosfamide plus mesna in malignant mesothelioma.

  Investigational new drugs 19921101

• Response of cyclophosphamide-resistant Wegener's granulomatosis to etoposide.

  Lancet (London, England) 19920815

• Mesna side effects which imitate vasculitis.

  The Clinical investigator 19920801

• Comparison of N-acetylcysteine and mesna as uroprotectors with ifosfamide combination chemotherapy in refractory germ cell tumors.

  Investigational new drugs 19920801

• National survey of use of mesna for the prevention of cyclophosphamide-induced hemorrhagic cystitis in recipients of bone marrow transplants.

  Mayo Clinic proceedings 19920601

• Feasibility and efficacy of arginine 2-mercaptoethanesulfonate (ARGIMESNA) in the prevention of hemorragic cystitis from ifosfamide (IFO).

  Annals of oncology : official journal of the European Society for Medical Oncology 19920401

• Primary tumour mutant p53 gene protein and epidermal growth factor receptor expression and doxorubicin plus ifosfamide for recurrent breast cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology 19920301

• Hemorrhagic cystitis complicating bone marrow transplantation.

  Mayo Clinic proceedings 19920201

• Ifosfamide and mesna in previously treated advanced epithelial ovarian cancer: activity in platinum-resistant disease.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19920201

• Uroepithelial and nephrotubular toxicity in patients receiving ifosfamide/mesna: measurement of urinary N-acetyl-beta-D-glucosaminidase and beta-2-microglobulin.

  European journal of cancer (Oxford, England : 1990) 19920101

• Ifosfamide with mesna in squamous carcinoma of the cervix: phase II results in patients with advanced or recurrent disease.

  Gynecologic oncology 19911101

• Mesna versus hyperhydration for the prevention of cyclophosphamide-induced hemorrhagic cystitis in bone marrow transplantation.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19911101

• Allergic reactions to mesna.

  Lancet (London, England) 19910914

• Ifosfamide/mesna. A review of its antineoplastic activity, pharmacokinetic properties and therapeutic efficacy in cancer.

  Drugs 19910901

• Allergic reactions to mesna.

  Lancet (London, England) 19910810

• Ifosfamide continuous infusion without mesna. A phase I trial of a 14-day cycle.

  Cancer 19910215

• A phase I study of high-dose ifosfamide and escalating doses of carboplatin with autologous bone marrow support.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19910201

• Placebo-controlled double-blind comparative study on the preventive efficacy of mesna against ifosfamide-induced urinary disorders.

  Journal of cancer research and clinical oncology 19910101

• [Ifosfamide-induced urinary bladder lesion and its inhibition by mesna].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19900801

• Ifosfamide with mesna uroprotection in the management of lung cancer.

  American journal of clinical oncology 19900401

• Ifosfamide and mesna.

  Clinical pharmacy 19900301

• Dana-Farber Cancer Institute studies in advanced sarcoma.

  Seminars in oncology 19900201

• Encephalopathy with hyponatremia and inappropriate arginine vasopressin secretion following an intravenous ifosfamide infusion.

  Annals of oncology : official journal of the European Society for Medical Oncology 19900101

• Mesna excretion and ifosfamide nephrotoxicity in children.

  Cancer research 19891215

• Ifosfamide is an inactive substance in the treatment of pancreatic carcinoma. The Gastrointestinal Tumor Study Group.

  Cancer 19891115

• Methyl-coenzyme-M reductase from Methanobacterium thermoautotrophicum (strain Marburg). Purity, activity and novel inhibitors.

  European journal of biochemistry 19890901

• Ifosfamide and mesna in the treatment of malignant disease mesna as urothelial protector.

  Investigational new drugs 19890701

• Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication.

  Arzneimittel-Forschung 19890601

• Oxazaphosphorine cytostatics: past-present-future. Seventh Cain Memorial Award lecture.

  Cancer research 19890101

• Severe renal failure following high-dose ifosfamide and mesna.

  Cancer chemotherapy and pharmacology 19890101

• Drug-induced encephalopathy after previous ifosfamide treatment.

  Lancet (London, England) 19881105

• Fatal hypokalaemia associated with ifosfamide/mesna chemotherapy.

  Lancet (London, England) 19880514

• Treatment of gynecological adenocarcinomas with a combination of ifosfamide, adriamycin and cisplatin.

  Nihon Sanka Fujinka Gakkai zasshi 19880501

• [Encephalopathy caused by an ifosfamide-mesna combination].

  Presse medicale (Paris, France : 1983) 19880402

• Phase II trial of ifosfamide and mesna in previously treated patients with non-Hodgkin's lymphoma: Cancer and Leukemia Group B Study 8552.

  Medical and pediatric oncology 19880101

• Ifosfamide/mesna related encephalopathy: a case report with a possible role of phenobarbital in enhancing neurotoxicity.

  Bulletin du cancer 19880101

• Efficacy of mesna in preventing further cyclophosphamide-induced hemorrhagic cystitis.

  Medical and pediatric oncology 19880101

• Ifosfamide with mesna uroprotection and etoposide: an effective regimen in the treatment of recurrent sarcomas and other tumors of children and young adults.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19870801

• Irreversible encephalopathy with ifosfamide/mesna.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19870801

• The efficacy of mesna (2-mercaptoethane sodium sulfonate) as a uroprotectant in patients with hemorrhagic cystitis receiving further oxazaphosphorine chemotherapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19870501

• Ifosfamide/mesna encephalopathy.

  Lancet (London, England) 19870425

• Ifosfamide neurotoxicity in children.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19870301

• Encephalopathy with rapid infusion ifosfamide/mesna.

  Lancet (London, England) 19870214

• Ifosfamide-induced subclinical tubular nephrotoxicity despite mesna.

  Cancer treatment reports 19870201

• Electron microscopic investigations of the cyclophosphamide-induced lesions of the urinary bladder of the rat and their prevention by mesna.

  Urologia internationalis 19870101

• Blurring of vision due to ifosfamide.

  Cancer chemotherapy and pharmacology 19870101

• Avoiding ifosfamide/mesna encephalopathy.

  Lancet (London, England) 19860816

• Central nervous system toxicity following the treatment of pediatric patients with ifosfamide/mesna.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19860801

• Prediction of ifosfamide/mesna associated encephalopathy.

  European journal of cancer & clinical oncology 19860701

• Phase II study of ifosfamide in cervical cancer.

  Cancer treatment reports 19860601

• The protective effect of 2-mercapto-ethane sulfonate (MESNA) on hemorrhagic cystitis induced by high-dose ifosfamide treatment tested by a randomized crossover trial.

  Japanese journal of clinical oncology 19860601

• CNS-side effects induced by Ifosfamide-Mesna in children with osteosarcomas.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 19860101

• Ifosfamide plus mesna with and without adriamycin in soft tissue sarcoma.

  Cancer chemotherapy and pharmacology 19860101

• Cause and prevention of mafosfamide-induced venous pain.

  Investigational new drugs 19860101

• Ifosfamide, mesna, and encephalopathy.

  Lancet (London, England) 19850615

• Phase II trial of ifosfamide with mesna in previously treated metastatic sarcoma.

  Cancer treatment reports 19850501

• Ifosfamide/mesa and encephalopathy.

  Lancet (London, England) 19850330

• Encephalopathy associated with ifosphamide/mesna therapy.

  Lancet (London, England) 19850216

• Comparison of mesna with forced diuresis to prevent cyclophosphamide induced haemorrhagic cystitis in marrow transplantation: a prospective randomised study.

  British journal of cancer 19841201

• Hemorrhagic cystitis after conditioning for bone marrow transplantation and its prophylaxis.

  Japanese journal of clinical oncology 19841201

• Sodium-2-mercaptoethanesulfonate (MESNA) and ifosfamide nephrotoxicity.

  European journal of cancer & clinical oncology 19841101

• Prevention of cyclophosphamide cystitis with 2-mercaptoethane sodium sulfonate: a histologic study.

  The Journal of urology 19840901

• [Prevention of tumor formation in the bladder by sodium-2-mercaptoethane sulfonate (mesna). Experimental studies and clinical consequences].

  Der Urologe. Ausg. A 19840901

• The use of sodium 2-mercaptoethane sulfonate to prevent cyclophosphamide cystitis.

  The Journal of urology 19840501

• Failure of 2-mercaptoethane sulphonate sodium (mesna) to protect against ifosfamide nephrotoxicity.

  European journal of cancer & clinical oncology 19840301

• Experience with mesna in patients receiving allogeneic bone marrow transplants for poor prognostic leukaemia.

  Cancer treatment reviews 19830901

• Prevention of cyclophosphamide-induced carcinogenesis in the urinary bladder of rats by administration of mesna.

  Cancer treatment reviews 19830901

• Prevention of urinary bladder tumors in cyclophosphamide-treated rats by additional medication with the uroprotectors sodium 2-mercaptoethane sulfonate (mesna) and disodium 2,2'-dithio-bis-ethane sulfonate (dimesna).

  Cancer 19830215

• Treatment of ifosfamide-induced urothelial toxicity by oral administration of sodium 2-mercaptoethane sulphonate (MESNA) to patients with inoperable lung cancer.

  European journal of cancer & clinical oncology 19830201

• [Prevention of urotoxic actions of cyclophosphamide and ifosfamide by dimesna (preliminary communication) (author's transl)].

  Arzneimittel-Forschung 19820101

• Mesnum as a protector against kidney and bladder toxicity with high-dose ifosfamide treatment.

  Cancer chemotherapy and pharmacology 19820101

• Prophylaxis of haemorrhagic cystitis due to cyclophosphamide-conditioning for bone marrow transplantation.

  Blut 19811101

• Detoxification of urotoxic oxazaphosphorines by sulfhydryl compounds.

  Journal of cancer research and clinical oncology 19810101

• [Clinical evaluation of Mitexan in the prevention of urinary tract complications during treatment with Holoxan].

  Nowotwory 19810101

• Prevention of isophosphamide-induced urothelial toxicity with 2-mercaptoethane sulphonate sodium (mesnum) in patients with advanced carcinoma.

  Lancet (London, England) 19800927

• [High-dose ifosfamide therapy: systemic use of a mucolytic agent for the reduction of urotoxicity].

  Schweizerische medizinische Wochenschrift 19791208