2002-16-6 | 1-Phenylguanidine

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$106.00	$75.00
1g	98%	in stock	$171.00	$120.00
5g	98%	in stock	$480.00	$336.00
25g	98%	in stock	$1,412.00	$989.00

Description

• Catalog Number: AB09463
• Chemical Name: 1-Phenylguanidine
• CAS Number: 2002-16-6
• Molecular Formula: C7H9N3
• Molecular Weight: 135.1665
• MDL Number: MFCD00092876
• SMILES: NC(=N)Nc1ccccc1

Computed Properties

• Complexity: 121
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 0.5

Literature

• Enzyme-specific activation versus leaving group ability.

  Chembiochem : a European journal of chemical biology 20120813

• A computational study of anion-modulated cation-π interactions.

  The journal of physical chemistry. B 20120524

• Putative binding sites, and pathways to them, for amidine and guanidine current inhibitors on acid-sensing ion channels (ASIC). A theoretical approach with hASIC1a homology model.

  Chemistry & biodiversity 20120201

• Effect of microhydration on the guanidinium···benzene interaction.

  The Journal of chemical physics 20111207

• Papain-catalyzed peptide bond formation: enzyme-specific activation with guanidinophenyl esters.

  Chembiochem : a European journal of chemical biology 20110919

• Simple preparation of pacific cod trypsin for enzymatic Peptide synthesis.

  Journal of amino acids 20110101

• Crystal structure and experimental and theoretical studies of the second-order nonlinear optical properties of salts of triphenylguanidine with carboxylic acids.

  The journal of physical chemistry. A 20100225

• Enhancing the intestinal absorption of molecules containing the polar guanidino functionality: a double-targeted prodrug approach.

  Journal of medicinal chemistry 20100128

• Design and discovery of 1,3-benzodiazepines as novel dopamine antagonists.

  Bioorganic & medicinal chemistry letters 20090901

• Small molecule microarrays of RNA-focused peptoids help identify inhibitors of a pathogenic group I intron.

  ACS chemical biology 20090417

• Transport of guanidine compounds by human organic cation transporters, hOCT1 and hOCT2.

  Biochemical pharmacology 20090415

• Effect of subinhibitory concentration of some established and experimental antifungal compounds on the germ tube formation in Candida albicans.

  Folia microbiologica 20070101

• Phenylguanidines as selective nonpeptide melanocortin-5 receptor antagonists.

  Journal of medicinal chemistry 20040729

• Synthesis and in vitro antifungal activity of 4-substituted phenylguanidinium salts.

  Farmaco (Societa chimica italiana : 1989) 20040601

• Potent bivalent inhibition of human tryptase-beta by a synthetic inhibitor.

  Biological chemistry 20031201

• Conformationally-restricted analogues and partition coefficients of the 5-HT3 serotonin receptor ligands meta-chlorophenylbiguanide (mCPBG) and meta-chlorophenylguanidine (mCPG).

  Bioorganic & medicinal chemistry letters 20030324

• Synthesis and in vitro evaluation of N,N'-diphenyl and N-naphthyl-N'-phenylguanidines as N-methyl-D-aspartate receptor ion-channel ligands.

  Bioorganic & medicinal chemistry letters 20020617

• Solution-phase, parallel synthesis and pharmacological evaluation of acylguanidine derivatives as potential sodium channel blockers.

  Bioorganic & medicinal chemistry letters 20011217

• Optimization of a synthetic arginine receptor. Systematic tuning of noncovalent interactions.

  The Journal of organic chemistry 20010824

• The binding of arylguanidines at 5-HT(3) serotonin receptors: a structure-affinity investigation.

  Bioorganic & medicinal chemistry letters 20010618

• Chum salmon trypsin-catalyzed preferential formation of peptides containing D-amino acid.

  Amino acids 20010101