2004-06-0 | 6-Chloropurine ribonucleoside

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$10.00	$7.00
5g	97%	in stock	$31.00	$22.00
10g	97%	in stock	$37.00	$26.00
25g	97%	in stock	$66.00	$46.00
100g	97%	in stock	$245.00	$171.00

Description

• Catalog Number: AB09634
• Chemical Name: 6-Chloropurine ribonucleoside
• CAS Number: 2004-06-0
• Molecular Formula: C10H11ClN4O4
• Molecular Weight: 286.6717
• MDL Number: MFCD00005738
• SMILES: OC[C@H]1OC([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2Cl

Computed Properties

• Complexity: 339
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 2
• XLogP3: 0.3

Literature

• Biosynthesis of anti-HCV compounds using thermophilic microorganisms.

  Bioorganic & medicinal chemistry letters 20121001

• Suzuki-miyaura and sonogashira coupling of 6-chloropurines and -nucleosides in water.

  Organic letters 20090618

• 5'-O-masked 2'-deoxyadenosine analogues as lead compounds for hepatitis C virus (HCV) therapeutic agents.

  Bioorganic & medicinal chemistry 20071115

• Synthesis and biological evaluation of nucleoside analogues having 6-chloropurine as anti-SARS-CoV agents.

  Bioorganic & medicinal chemistry letters 20070501

• Introduction of a benzyl group onto the 2'-OH of 6-chloropurine 3'-O-benzoylriboside.

  Nucleosides, nucleotides & nucleic acids 20030101

• Anti-malarial activity of N(6)-substituted adenosine derivatives. Part I.

  Bioorganic & medicinal chemistry 20020301

• Synthesis and antiviral activity of carbocyclic analogues of 2'-deoxyribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8-azapurines.

  Journal of medicinal chemistry 19841101

• Synthesis and antiviral activity of certain carbamoylpyrrolopyrimidine and pyrazolopyrimidine nucleosides.

  Journal of medicinal chemistry 19821101

• Synthesis and antiviral activity of certain 9-beta-D-ribofuranosylpurine-6-carboxamides.

  Journal of medicinal chemistry 19810801

• Purine analogs as potential anticytomegalovirus agents.

  Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19690901