20362-31-6 | Arctiin

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$6.00	$4.00
10mg	98%	in stock	$9.00	$6.00
50mg	98%	in stock	$24.00	$17.00
250mg	95%	in stock	$106.00	$75.00
1g	95%	in stock	$306.00	$214.00

Description

• Catalog Number: AB04806
• Chemical Name: Arctiin
• CAS Number: 20362-31-6
• Molecular Formula: C27H34O11
• Molecular Weight: 534.5523
• MDL Number: MFCD00870630
• SMILES: OC[C@H]1O[C@@H](Oc2ccc(cc2OC)C[C@H]2C(=O)OC[C@@H]2Cc2ccc(c(c2)OC)OC)[C@@H]([C@H]([C@@H]1O)O)O

Computed Properties

• Complexity: 753
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 7
• Heavy Atom Count: 38
• Hydrogen Bond Acceptor Count: 11
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 10
• XLogP3: 1.8

Literature

• Effects of arctiin on streptozotocin-induced diabetic retinopathy in Sprague-Dawley rats.

  Planta medica 20120801

• Plasma pharmacokinetics and tissue distribution of arctiin and its main metabolite in rats by HPLC-UV and LC-MS.

  Planta medica 20120501

• [Effect of arctiin on mouse podocyte epithelial-mesenchymal transition induced by advanced oxidation protein products].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120301

• Antiasthmatic Effects of Herbal Complex MA and Its Fermented Product MA128.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• Effect of aqueous extract of Arctium lappa L. (burdock) roots on the sexual behavior of male rats.

  BMC complementary and alternative medicine 20120101

• Therapeutic effects of liposome-enveloped Ligusticum chuanxiong essential oil on hypertrophic scars in the rabbit ear model.

  PloS one 20120101

• Optimum yields of dibenzylbutyrolactone-type lignans from Cynareae fruits, during their ripening, germination and enzymatic hydrolysis processes, determined by on-line chromatographic methods.

  Phytochemical analysis : PCA 20120101

• Metabolism of ginsenoside Rb1 by human intestinal microflora and cloning of its metabolizing β-D-glucosidase from Bifidobacterium longum H-1.

  Biological & pharmaceutical bulletin 20120101

• Arctigenin isolated from the seeds of Arctium lappa ameliorates memory deficits in mice.

  Planta medica 20110901

• [Study on correlation between ITS sequence of Arctium lappa and quality of Fructus Arctii].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110701

• Antiasthmatic action of dibenzylbutyrolactone lignans from fruits of Forsythia viridissima on asthmatic responses to ovalbumin challenge in conscious guinea-pigs.

  Phytotherapy research : PTR 20110301

• Antioxidative and in vitro antiproliferative activity of Arctium lappa root extracts.

  BMC complementary and alternative medicine 20110101

• Arctigenin from Arctium lappa inhibits interleukin-2 and interferon gene expression in primary human T lymphocytes.

  Chinese medicine 20110101

• Anti-inflammatory function of arctiin by inhibiting COX-2 expression via NF-κB pathways.

  Journal of inflammation (London, England) 20110101

• Organic parasite control for poultry and rabbits in British Columbia, Canada.

  Journal of ethnobiology and ethnomedicine 20110101

• Arctigenin efficiently enhanced sedentary mice treadmill endurance.

  PloS one 20110101

• Bioactivity-guided isolation of antiproliferative compounds from Centaurea arenaria.

  Phytotherapy research : PTR 20101101

• Determination of the major constituents in fruit of Arctium lappa L. by matrix solid-phase dispersion extraction coupled with HPLC separation and fluorescence detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

• On-line coupling of counter-current chromatography and macroporous resin chromatography for continuous isolation of arctiin from the fruit of Arctium lappa L.

  Journal of chromatography. A 20100813

• Mass fragmentation study of the trimethylsilyl derivatives of arctiin, matairesinoside, arctigenin, phylligenin, matairesinol, pinoresinol and methylarctigenin: their gas and liquid chromatographic analysis in plant extracts.

  Journal of chromatography. A 20100305

• Metabolic profile of the bioactive compounds of burdock (Arctium lappa) seeds, roots and leaves.

  Journal of pharmaceutical and biomedical analysis 20100120

• Production of enterodiol from defatted flaxseeds through biotransformation by human intestinal bacteria.

  BMC microbiology 20100101

• Lignans inhibit cell growth via regulation of Wnt/beta-catenin signaling.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

• Therapeutic effect of arctiin and arctigenin in immunocompetent and immunocompromised mice infected with influenza A virus.

  Biological & pharmaceutical bulletin 20100101

• Dibenzylbutyrolactone lignans from Forsythia koreana fruits attenuate lipopolysaccharide-induced inducible nitric oxide synthetase and cyclooxygenase-2 expressions through activation of nuclear factor-κb and mitogen-activated protein kinase in RAW264.7 cells.

  Biological & pharmaceutical bulletin 20100101

• Bioassay-guided isolation and identification of active compounds from Fructus Arctii against Dactylogyrus intermedius (Monogenea) in goldfish (Carassius auratus).

  Parasitology research 20091201

• Ameliorative effects of arctiin from Arctium lappa on experimental glomerulonephritis in rats.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20091101

• Further studies on a human intestinal bacterium Ruminococcus sp. END-1 for transformation of plant lignans to mammalian lignans.

  Journal of agricultural and food chemistry 20090826

• Natural Arctium lappa fruit extract improves the clinical signs of aging skin.

  Journal of cosmetic dermatology 20081201

• In vitro and in vivo anti-allergic effects of Arctium lappa L.

  Experimental biology and medicine (Maywood, N.J.) 20081101

• Treatment with SI000413, a new herbal formula, ameliorates murine collagen-induced arthritis.

  Biological & pharmaceutical bulletin 20080701

• Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression.

  Oncology reports 20080301

• Microemulsion electrokinetic chromatography for the separation of arctiin and arctigenin in Fructus Arctii and its herbal preparations.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071201

• The chemopreventive effects of Saussurea salicifolia through induction of apoptosis and phase II detoxification enzyme.

  Biological & pharmaceutical bulletin 20071201

• Inhibitory effect of nordihydroguaiaretic acid, a plant lignan, on Helicobacter pylori-associated gastric carcinogenesis in Mongolian gerbils.

  Cancer science 20071101

• Isolation and characterization of a human intestinal bacterium, Eubacterium sp. ARC-2, capable of demethylating arctigenin, in the essential metabolic process to enterolactone.

  Biological & pharmaceutical bulletin 20070501

• A new lignan glycoside from the stem bark of Styrax japonica S. et Z.

  Archives of pharmacal research 20070401

• Antiviral activity of berberine and related compounds against human cytomegalovirus.

  Bioorganic & medicinal chemistry letters 20070315

• [Relative adscriptions of components in the effective fractions of Yinqiao decoction and its composing individual herbs].

  Yao xue xue bao = Acta pharmaceutica Sinica 20070201

• In-vitro and in-vivo anti-inflammatory action of the ethanol extract of Trachelospermi caulis.

  The Journal of pharmacy and pharmacology 20070101

• Lack of a significant effect of arctiin on development of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats.

  Nutrition and cancer 20070101

• Americanin, a bioactive dibenzylbutyrolactone lignan, from the seeds of Centaurea americana.

  Phytochemistry 20061101

• [Study on condition for extraction of arctiin from fruits of Arctium lappa using supercritical fluid extraction].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060801

• Arctigenin from Fructus Arctii is a novel suppressor of heat shock response in mammalian cells.

  Cell stress & chaperones 20060601

• Determination of phillyrin in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies.

  Journal of pharmaceutical and biomedical analysis 20060503

• A high performance liquid chromatography method for the simultaneous determination of arctiin, chlorogenic acid and glycyrrhizin in a Chinese proprietary medicine.

  Journal of pharmaceutical and biomedical analysis 20050915

• [Dyuamical studies on metabolic chemistry of lignans from seeds of Arctium lappa].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050801

• Lack of significant modifying effect of arctiin on prostate carcinogenesis in probasin/SV40 T antigen transgenic rats.

  Cancer letters 20050526

• Application of preparative high-speed counter-current chromatography for separation and purification of arctiin from Fructus Arctii.

  Journal of chromatography. A 20050121

• Isolation and identification of arctiin and arctigenin in leaves of burdock (Arctium lappa L.) by polyamide column chromatography in combination with HPLC-ESI/MS.

  Phytochemical analysis : PCA 20050101

• [Clinical observation on treatment of diabetic nephropathy with compound fructus arctii mixture].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040701

• Modulation of anti-adhesion molecule MUC-1 is associated with arctiin-induced growth inhibition in PC-3 cells.

  The Prostate 20040515

• Isolation and identification of biologically active compounds from Forsythia viridissima flowers.

  Acta poloniae pharmaceutica 20040101

• The content of lignan glycosides in Forsythia flowers and leaves.

  Acta poloniae pharmaceutica 20040101

• Effects of forsythia fruit extracts and lignan on lipid metabolism.

  BioFactors (Oxford, England) 20040101

• Lack of significant inhibitory effects of a plant lignan tracheloside on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in female Sprague-Dawley rats.

  Cancer letters 20031028

• Transformation of arctiin to estrogenic and antiestrogenic substances by human intestinal bacteria.

  Chemical & pharmaceutical bulletin 20030401

• Simultaneous determination of chlorogenic acid, forsythin and arctiin in Chinese traditional medicines preparation by reversed phase-HPLC.

  Chemical & pharmaceutical bulletin 20030401

• [Isolation and elucidation of chemical constituents with antiviral action from yinqiaosan on influenza virus].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030101

• Chemoprevention of heterocyclic amine-induced mammary carcinogenesis in rats.

  Environmental and molecular mutagenesis 20020101

• Neuroprotective dibenzylbutyrolactone lignans of Torreya nucifera.

  Planta medica 20010701

• Effects of the lignan, arctiin, on 17-beta ethinyl estradiol promotion of preneoplastic liver cell foci development in rats.

  Anticancer research 19980101

• Differential in vitro anti-HIV activity of natural lignans.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 19900101