20702-77-6 | 1-Propanone, 1-[4-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)-

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$13.00	$9.00
1g	95%	in stock	$15.00	$10.00
5g	95%	in stock	$52.00	$36.00
25g	95%	in stock	$54.00	$38.00

Description

• Catalog Number: AB17515
• Chemical Name: 1-Propanone, 1-[4-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)-
• CAS Number: 20702-77-6
• Molecular Formula: C28H36O15
• Molecular Weight: 612.5764
• MDL Number: MFCD03840557
• SMILES: OC[C@H]1O[C@@H](Oc2cc(O)c(c(c2)O)C(=O)CCc2ccc(c(c2)O)OC)[C@@H]([C@H]([C@@H]1O)O)O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O

Computed Properties

• Complexity: 882
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 10
• Heavy Atom Count: 43
• Hydrogen Bond Acceptor Count: 15
• Hydrogen Bond Donor Count: 9
• Rotatable Bond Count: 10
• XLogP3: -0.3

Literature

• Protective effects of neohesperidin dihydrochalcone against carbon tetrachloride-induced oxidative damage in vivo and in vitro.

  Chemico-biological interactions 20140425

• Expression of Na+/glucose co-transporter 1 (SGLT1) is enhanced by supplementation of the diet of weaning piglets with artificial sweeteners.

  The British journal of nutrition 20100901

• Positive allosteric modulators of the human sweet taste receptor enhance sweet taste.

  Proceedings of the National Academy of Sciences of the United States of America 20100309

• Antioxidant properties of neohesperidin dihydrochalcone: inhibition of hypochlorous acid-induced DNA strand breakage, protein degradation, and cell death.

  Biological & pharmaceutical bulletin 20070201

• The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor.

  BMC structural biology 20070101

• Metabolic engineering of plant cells for biotransformation of hesperedin into neohesperidin, a substrate for production of the low-calorie sweetener and flavor enhancer NHDC.

  Journal of agricultural and food chemistry 20051214

• Degradation of neohesperidin dihydrochalcone by human intestinal bacteria.

  Journal of agricultural and food chemistry 20050309

• Crystal architecture and conformational properties of the inclusion complex, neohesperidin dihydrochalcone-cyclomaltoheptaose (beta-cyclodextrin), by X-ray diffraction.

  Carbohydrate research 20040823

• Embryotoxicity and teratogenicity study with neohesperidin dihydrochalcone in rats.

  Regulatory toxicology and pharmacology : RTP 20040801

• Some sweet and bitter tastants stimulate inhibitory pathway of adenylyl cyclase via melatonin and alpha 2-adrenergic receptors in Xenopus laevis melanophores.

  American journal of physiology. Cell physiology 20031101

• [Determination of neohesperidin dihydrochalcone in foods].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010201

• PROP (6-n-Propylthiouracil) tasting and sensory responses to caffeine,sucrose, neohesperidin dihydrochalcone and chocolate.

  Chemical senses 20010101

• Improved water solubility of neohesperidin dihydrochalcone in sweetener blends.

  Journal of agricultural and food chemistry 20010101

• Screening for new compounds with antiherpes activity.

  Antiviral research 19841001