20784-50-3 | Isobavachalcone

Packsize	Purity	Availability	Price	Discounted Price
5mg	≥98%	in stock	$105.00	$73.00
10mg	≥98%	in stock	$184.00	$129.00
20mg	≥98%	in stock	$309.00	$217.00
50mg	≥98%	in stock	$763.00	$534.00
100mg	≥98%	in stock	$1,341.00	$939.00

Description

• Catalog Number: AB18141
• Chemical Name: Isobavachalcone
• CAS Number: 20784-50-3
• Molecular Formula: C20H20O4
• Molecular Weight: 324.3704
• MDL Number: MFCD00902090
• SMILES: CC(=CCc1c(O)ccc(c1O)C(=O)/C=C/c1ccc(cc1)O)C

Computed Properties

• Complexity: 470
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 5
• XLogP3: 5.1

Literature

• Separation of isomeric bavachin and isobavachalcone in the fructus Psoraleae by capillary electrophoresis-mass spectrometry.

  Journal of separation science 20120701

• Isobavachalcone: an overview.

  Chinese journal of integrative medicine 20120701

• Antibacterial activity of chalcones, hydrazones and oxadiazoles against methicillin-resistant Staphylococcus aureus.

  Bioorganic & medicinal chemistry letters 20120101

• Determination of bavachin and isobavachalcone in Fructus Psoraleae by high-performance liquid chromatography with electrochemical detection.

  Journal of separation science 20110301

• Evaluation of flavonoids from Dorstenia barteri for their antimycobacterial, antigonorrheal and anti-reverse transcriptase activities.

  Acta tropica 20101001

• Abrogation of Akt signaling by Isobavachalcone contributes to its anti-proliferative effects towards human cancer cells.

  Cancer letters 20100828

• Total synthesis, antiprotozoal and cytotoxicity activities of rhuschalcone VI and analogs.

  Bioorganic & medicinal chemistry 20100401

• Inhibitory effects of bakuchiol, bavachin, and isobavachalcone isolated from Piper longum on melanin production in B16 mouse melanoma cells.

  Bioscience, biotechnology, and biochemistry 20100101

• [Flavonoids from the leaves of Morus alba L].

  Yao xue xue bao = Acta pharmaceutica Sinica 20100101

• Bavachin and isobavachalcone, acyl-coenzyme A: cholesterol acyltransferase inhibitors from Psoralea corylifolia.

  Archives of pharmacal research 20081101

• Naturally occurring homoisoflavonoids function as potent protein tyrosine kinase inhibitors by c-Src-based high-throughput screening.

  Journal of medicinal chemistry 20080814

• Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma.

  Biological & pharmaceutical bulletin 20071001

• Chemical fingerprint and quantitative analysis of fructus psoraleae by high-performance liquid chromatography.

  Journal of separation science 20070401

• Compounds with DNA cleaving activity from Kadsura ananosma.

  Die Pharmazie 20061001

• Prenylated flavonoids from the heartwood of Artocarpus communis with inhibitory activity on lipopolysaccharide-induced nitric oxide production.

  Journal of natural products 20060401

• Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects.

  Journal of natural products 20060101

• Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects.

  Cancer letters 20031125

• Fatty acid synthase inhibitors from plants: isolation, structure elucidation, and SAR studies.

  Journal of natural products 20021201

• Antioxidative components of Psoralea corylifolia (Leguminosae).

  Phytotherapy research : PTR 20020901

• Aromatase inhibitors from Broussonetia papyrifera.

  Journal of natural products 20011001

• Antifungal chalcones from Maclura tinctoria.

  Planta medica 20010201

• Cytotoxic activity of low molecular weight polyphenols against human oral tumor cell lines.

  Anticancer research 20000101