21279-64-1 | 5-Chloropyrazine-2-carboxamide

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$17.00	$12.00
5g	98%	in stock	$70.00	$49.00
10g	98%	in stock	$124.00	$87.00
25g	98%	in stock	$259.00	$182.00

Description

• Catalog Number: AD61239
• Chemical Name: 5-Chloropyrazine-2-carboxamide
• CAS Number: 21279-64-1
• Molecular Formula: C5H4ClN3O
• Molecular Weight: 157.5578
• MDL Number: MFCD10686873
• SMILES: NC(=O)c1cnc(cn1)Cl

Computed Properties

• Complexity: 141
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: -0.5

Literature

• Alkylamino derivatives of pyrazinamide: synthesis and antimycobacterial evaluation.

  Bioorganic & medicinal chemistry letters 20140115

• Synthesis and antimycobacterial evaluation of N-substituted 5-chloropyrazine-2-carboxamides.

  Bioorganic & medicinal chemistry letters 20130615

• The regulation of sulfur metabolism in Mycobacterium tuberculosis.

  PLoS pathogens 20110701

• The proteomic response of Mycobacterium smegmatis to anti-tuberculosis drugs suggests targeted pathways.

  Journal of proteome research 20080301

• Inhibition of isolated Mycobacterium tuberculosis fatty acid synthase I by pyrazinamide analogs.

  Antimicrobial agents and chemotherapy 20070701

• Pyrazinoic acid and its n-propyl ester inhibit fatty acid synthase type I in replicating tubercle bacilli.

  Antimicrobial agents and chemotherapy 20070201

• Effects of pyrazinamide on fatty acid synthesis by whole mycobacterial cells and purified fatty acid synthase I.

  Journal of bacteriology 20020401

• In vitro antimycobacterial activity of 5-chloropyrazinamide.

  Antimicrobial agents and chemotherapy 19980201