221244-14-0 | PP1 Analog II, 1NM-PP1

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$33.00	$23.00
5mg	95%	in stock	$146.00	$102.00
10mg	95%	in stock	$178.00	$125.00
25mg	95%	in stock	$282.00	$198.00
200mg	95%	in stock	$2,158.00	$1,511.00
500mg	95%	in stock	$4,511.00	$3,158.00
1g	95%	in stock	$6,360.00	$4,452.00
2g	95%	in stock	$10,562.00	$7,393.00

Description

• Catalog Number: AD59487
• Chemical Name: PP1 Analog II, 1NM-PP1
• CAS Number: 221244-14-0
• Molecular Formula: C20H21N5
• Molecular Weight: 331.4142
• MDL Number: MFCD17010191
• SMILES: Nc1ncnc2c1c(Cc1cccc3c1cccc3)nn2C(C)(C)C

Computed Properties

• Complexity: 462
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 25
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 3.9

Literature

• A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.

  The Biochemical journal 20130415

• Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity.

  Journal of medicinal chemistry 20120308

• Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.

  Nature biotechnology 20111101

• Chemical genetic analysis of the regulatory role of Cdc2p in the S. pombe septation initiation network.

  Journal of cell science 20080315

• The selectivity of protein kinase inhibitors: a further update.

  The Biochemical journal 20071215

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Assignment of protein function in the postgenomic era.

  Nature chemical biology 20050801