22951-96-8 | L-2-Thienylalanine

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$15.00	$11.00
1g	97%	in stock	$31.00	$22.00
5g	97%	in stock	$123.00	$86.00
100g	97%	in stock	$2,314.00	$1,620.00

Description

• Catalog Number: AB21209
• Chemical Name: L-2-Thienylalanine
• CAS Number: 22951-96-8
• Molecular Formula: C7H9NO2S
• Molecular Weight: 171.2169
• MDL Number: MFCD00064335
• SMILES: OC(=O)[C@H](Cc1cccs1)N

Computed Properties

• Complexity: 151
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• XLogP3: -1.7

Literature

• Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis.

  Current chemical genomics 20100101

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• 2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding.

  Journal of molecular biology 20031031

• Substrate-induced conformational transition in human phenylalanine hydroxylase as studied by surface plasmon resonance analyses: the effect of terminal deletions, substrate analogues and phosphorylation.

  The Biochemical journal 20030201

• Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation.

  Journal of molecular biology 20020726