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Neolignans from leaves of Nectandra leucantha (Lauraceae) display in vitro antitrypanosomal activity via plasma membrane and mitochondrial damages.
Chemico-biological interactions 20171101
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Hepatotoxicity in mice of a novel anti-parasite drug candidate hydroxymethylnitrofurazone: a comparison with Benznidazole.
PLoS neglected tropical diseases 20141001
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Design, synthesis, and evaluation of potential prodrugs of DFMO for reductive activation.
Bioorganic & medicinal chemistry letters 20121101
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Antitrypanosomal and antioxidant properties of 4-hydroxycoumarins derivatives.
Bioorganic & medicinal chemistry letters 20120901
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Reactivation of Chagas' disease: cutaneous manifestations in two immunosuppressed patients.
International journal of dermatology 20120701
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Novel 3-nitro-1H-1,2,4-triazole-based amides and sulfonamides as potential antitrypanosomal agents.
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Update on field use of the available drugs for the chemotherapy of human African trypanosomiasis.
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The Lancet. Infectious diseases 20120301
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The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: evidence for involvement of breast cancer resistance protein.
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Bioorganic & medicinal chemistry 20111115
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Apoptosis : an international journal on programmed cell death 20111001
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Drug resistance in human African trypanosomiasis.
Future microbiology 20110901
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Ligand-based discovery of novel trypanosomicidal drug-like compounds: in silico identification and experimental support.
European journal of medicinal chemistry 20110801
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Antiparasitic prodrug nifurtimox: revisiting its activation mechanism.
Future microbiology 20110801
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In search of patterns over physicochemical properties and pharmacological activities for a set of [MCl₂(thiosemicarbazone)] complexes (M=Pt/Pd): support for multiple mechanisms of antichagasic action excluding DNA-bonding in vivo?
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Antitrypanosomal therapy for chronic Chagas' disease.
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Biomedica : revista del Instituto Nacional de Salud 20110601
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Bulletin du cancer 20110501
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Medecine tropicale : revue du Corps de sante colonial 20110401
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Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6.
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The distribution of nifurtimox across the healthy and trypanosome-infected murine blood-brain and blood-cerebrospinal fluid barriers.
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A phase 1 study of nifurtimox in patients with relapsed/refractory neuroblastoma.
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Current topics in medicinal chemistry 20110101
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On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences.
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Acta tropica 20090701
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Study of 5-nitroindazoles' anti-Trypanosoma cruzi mode of action: electrochemical behaviour and ESR spectroscopic studies.
European journal of medicinal chemistry 20090401
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Bioorganic & medicinal chemistry 20090215
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Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates.
Bioorganic & medicinal chemistry 20090115
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Nitroreductive metabolic activation of some carcinogenic nitro heterocyclic food contaminants in rat mammary tissue cellular fractions.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101
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European journal of medicinal chemistry 20081001
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Memorias do Instituto Oswaldo Cruz 20080901
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European journal of medicinal chemistry 20080801
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New trypanocidal hybrid compounds from the association of hydrazone moieties and benzofuroxan heterocycle.
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European journal of medicinal chemistry 20080501
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Imidazolidines as new anti-Trypanosoma cruzi agents: biological evaluation and structure-activity relationships.
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Bioorganic & medicinal chemistry 20080115
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Heteroallyl-containing 5-nitrofuranes as new anti-Trypanosoma cruzi agents with a dual mechanism of action.
Bioorganic & medicinal chemistry 20080101
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Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses 20070801
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Bioorganic & medicinal chemistry 20070401
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Equivalence trial of melarsoprol and nifurtimox monotherapy and combination therapy for the treatment of second-stage Trypanosoma brucei gambiense sleeping sickness.
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Revista da Sociedade Brasileira de Medicina Tropical 20070101
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Molecular and biochemical parasitology 20060401
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Bioorganic & medicinal chemistry 20051201
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Bioorganic & medicinal chemistry 20051201
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Biological research 20040101
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Bioorganic & medicinal chemistry 20030612
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Biological characterization of a beta-galactosidase expressing clone of Trypanosoma cruzi CL strain.
Memorias do Instituto Oswaldo Cruz 20021201
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Toxicology letters 20021115
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