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Effect of glucagon-like peptide 2 on hepatic, renal, and intestinal disposition of 1-chloro-2,4-dinitrobenzene.
Drug metabolism and disposition: the biological fate of chemicals 20120701
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Application of human placental villous tissue explants to study ABC transporter mediated efflux of 2,4-dinitrophenyl-S-glutathione.
Current pharmaceutical biotechnology 20110501
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Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for 'ping pong' kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione.
The FEBS journal 20110101
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Modulated function of tissue efflux transporters under hyperbilirubinemia in rats.
European journal of pharmacology 20100625
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Interaction of Rhei Rhizoma extract with cytochrome P450 3A and efflux transporters in rats.
Die Pharmazie 20100501
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Induction of intestinal multidrug resistance-associated protein 2 (Mrp2) by spironolactone in rats.
European journal of pharmacology 20091125
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Influence of luminal monosaccharides on secretion of glutathione conjugates from rat small intestine in vitro.
International journal of pharmaceutics 20091103
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Effect of ursodeoxycholic acid treatment on the expression and function of multidrug resistance-associated protein 2 in rat intestine.
Journal of pharmaceutical sciences 20090801
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Physiological and pharmacological significance of glutathione-conjugate transport.
Journal of toxicology and environmental health. Part B, Critical reviews 20090801
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Aged garlic extract stimulates p-glycoprotein and multidrug resistance associated protein 2 mediated effluxes.
Biological & pharmaceutical bulletin 20090401
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Association mechanism of S-dinitrophenyl glutathione with two glutathione peroxidase mimics: 2, 2 cent-ditelluro- and 2, 2 cent-diseleno-bridged b-cyclodextrins.
Molecules (Basel, Switzerland) 20090225
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Functional reconstitution of RLIP76 catalyzing ATP-dependent transport of glutathione-conjugates.
International journal of oncology 20090101
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Formation and efflux of ATP-binding cassette transporter substrate 2,4-dinitrophenyl-S-glutathione from cultured human term placental villous tissue fragments.
Molecular pharmaceutics 20090101
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Simultaneous determination of 1-chloro-2,4-dinitrobenzene, 2,4-dinitrophenyl-S-glutathione and its metabolites for human placental disposition studies by high-performance liquid chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071101
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Site-specific bidirectional efflux of 2,4-dinitrophenyl-S-glutathione, a substrate of multidrug resistance-associated proteins, in rat intestine and Caco-2 cells.
The Journal of pharmacy and pharmacology 20070401
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Function of multidrug resistance-associated protein 2 in acute hepatic failure rats.
European journal of pharmacology 20060928
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Interaction of valproic acid and carbapenem antibiotics with multidrug resistance-associated proteins in rat erythrocyte membranes.
Epilepsy research 20060901
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Hepatic and extrahepatic synthesis and disposition of dinitrophenyl-S-glutathione in bile duct-ligated rats.
Drug metabolism and disposition: the biological fate of chemicals 20060801
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Increased glutathione conjugate transport: a possible compensatory protection mechanism against oxidative stress in obesity?
International journal of obesity (2005) 20060101
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Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5).
The FEBS journal 20050901
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Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4) that are present in human red cell membranes.
Biochemical pharmacology 20050815
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Modulation of intestinal transport of 2,4-dinitrophenyl-S-glutathione, a multidrug resistance-associated protein 2 substrate, by bilirubin treatment in rats.
The Journal of pharmacy and pharmacology 20050501
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Treatment of hyperbilirubinemia in Eisai hyperbilirubinemic rat by transfecting human MRP2/ABCC2 gene.
Pharmaceutical research 20050401
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Involvement of Mrp2 in hepatic and intestinal disposition of dinitrophenyl-S-glutathione in partially hepatectomized rats.
Toxicological sciences : an official journal of the Society of Toxicology 20050301
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Mechanisms involved in spironolactone-induced choleresis in the rat. Role of multidrug resistance-associated protein 2.
Biochemical pharmacology 20050201
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Effect of acetaminophen on expression and activity of rat liver multidrug resistance-associated protein 2 and P-glycoprotein.
Biochemical pharmacology 20040815
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Biliary secretory function in rats chronically intoxicated with aluminum.
Toxicological sciences : an official journal of the Society of Toxicology 20040501
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Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells.
Biochemical pharmacology 20040415
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Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione.
The international journal of biochemistry & cell biology 20040201
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Do multidrug resistance-associated protein-1 and -2 play any role in the elimination of estradiol-17 beta-glucuronide and 2,4-dinitrophenyl-S-glutathione across the blood-cerebrospinal fluid barrier?
Journal of pharmaceutical sciences 20040101
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Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein 1 in mouse embryo fibroblasts.
Biochemical and biophysical research communications 20031024
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cGMP and glutathione-conjugate transport in human erythrocytes.
European journal of biochemistry 20030901
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Mechanisms and physiological significance of the transport of the glutathione conjugate of 4-hydroxynonenal in human lens epithelial cells.
Investigative ophthalmology & visual science 20030801
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Expression of rat hepatic multidrug resistance-associated proteins and organic anion transporters in pregnancy.
American journal of physiology. Gastrointestinal and liver physiology 20020901
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Altered localization and activity of canalicular Mrp2 in estradiol-17beta-D-glucuronide-induced cholestasis.
Hepatology (Baltimore, Md.) 20020601
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The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP.
Journal of the American Society of Nephrology : JASN 20020301
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Effects of clotrimazole on transport mediated by multidrug resistance associated protein 1 (MRP1) in human erythrocytes and tumour cells.
European journal of biochemistry 20011201
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Energy-dependent export of the 13-oxooctadecadienoic acid-glutathione conjugate from HT-29 cells and plasma membrane vesicles.
Biochimica et biophysica acta 20010829
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Identification of the apical membrane-targeting signal of the multidrug resistance-associated protein 2 (MRP2/MOAT).
The Journal of biological chemistry 20010615
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Charged amino acids in the transmembrane domains are involved in the determination of the substrate specificity of rat Mrp2.
Molecular pharmacology 20010501
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Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver.
Hepatology (Baltimore, Md.) 20010501
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Trandolaprilat, an angiotensin-converting enzyme inhibitor, is not excreted in bile via an ATP-dependent active transporter (cMOAT).
Hypertension research : official journal of the Japanese Society of Hypertension 20010501
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Functional reassembly of ATP-dependent xenobiotic transport by the N- and C-terminal domains of RLIP76 and identification of ATP binding sequences.
Biochemistry 20010403
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Carrier-mediated hepatobiliary transport of a novel antifolate, N-[4-[(2,4-dianninopteridine-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl-L-homoglutamic acid, in rats.
Drug metabolism and disposition: the biological fate of chemicals 20010401
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Effect of multidrug resistance-reversing agents on transporting activity of human canalicular multispecific organic anion transporter.
Molecular pharmacology 19991201
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Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.
The Journal of clinical investigation 19980401
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Functional analysis of a canalicular multispecific organic anion transporter cloned from rat liver.
The Journal of biological chemistry 19980116
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Temocaprilat, a novel angiotensin-converting enzyme inhibitor, is excreted in bile via an ATP-dependent active transporter (cMOAT) that is deficient in Eisai hyperbilirubinemic mutant rats (EHBR).
The Journal of pharmacology and experimental therapeutics 19970301
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Ethinylestradiol treatment induces multiple canalicular membrane transport alterations in rat liver.
The Journal of clinical investigation 19930601