2646-71-1 | NADPH tetrasodium salt

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$6.00	$4.00
100mg	98%	in stock	$51.00	$36.00
1g	95%	in stock	$473.00	$331.00
5g	95%	in stock	$1,879.00	$1,316.00

Description

• Catalog Number: AB31122
• Chemical Name: NADPH tetrasodium salt
• CAS Number: 2646-71-1
• Molecular Formula: C21H26N7Na4O17P3
• Molecular Weight: 833.3482
• MDL Number: MFCD00036263
• SMILES: [Na]OP(=O)(OP(=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)OP(=O)(O[Na])O[Na])n1cnc2c1ncnc2N)O[Na])OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)N1C=CCC(=C1)C(=O)N

Computed Properties

• Complexity: 1380
• Covalently-Bonded Unit Count: 5
• Defined Atom Stereocenter Count: 8
• Heavy Atom Count: 52
• Hydrogen Bond Acceptor Count: 22
• Hydrogen Bond Donor Count: 5
• Rotatable Bond Count: 12

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  Journal of the American Chemical Society 20120509

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  Nature 20120509

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  Biochemistry 20120508

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  The FEBS journal 20120501

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  Journal of biotechnology 20120430

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  Molecular and cellular endocrinology 20120428

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  The Journal of biological chemistry 20120427

• Linking NAADP to ion channel activity: a unifying hypothesis.

  Science signaling 20120424

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  The Journal of biological chemistry 20120420

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  Journal of the American College of Cardiology 20120417

• Differential oxidation of two thiophene-containing regioisomers to reactive metabolites by cytochrome P450 2C9.

  Chemical research in toxicology 20120416

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  Chembiochem : a European journal of chemical biology 20120416

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  The Journal of biological chemistry 20120406

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  Cardiovascular therapeutics 20120401

• Oxidized phospholipid, 1-palmitoyl-2-(9'-oxo-nonanoyl)-glycerophosphocholine (PON-GPC), produced in the lung due to cigarette smoking, impairs immune function in macrophages.

  Lung 20120401

• NADPH-d-positive mast cells in the canine paranal sinus.

  Anatomia, histologia, embryologia 20120401

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  Progress in lipid research 20120401

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  Journal of vascular surgery 20120401

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  Toxicology in vitro : an international journal published in association with BIBRA 20120401

• Metformin reduces endogenous reactive oxygen species and associated DNA damage.

  Cancer prevention research (Philadelphia, Pa.) 20120401

• Crystal structure and fluorescence studies reveal the role of helical dimeric interface of staphylococcal FabG1 in positive cooperativity for NADPH.

  Proteins 20120401

• Role of thioredoxin in lung disease.

  Pulmonary pharmacology & therapeutics 20120401

• A fungal ketoreductase domain that displays substrate-dependent stereospecificity.

  Nature chemical biology 20120401

• LRRK2 as a modulator of lysosomal calcium homeostasis with downstream effects on autophagy.

  Autophagy 20120401

• Structure of the His269Arg mutant of the rat aldose reductase-like protein AKR1B14 complexed with NADPH.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20120401

• Structural analysis of Pneumocystis carinii dihydrofolate reductase complexed with NADPH and 2,4-diamino-6-[2-(5-carboxypent-1-yn-1-yl)-5-methoxybenzyl]-5-methylpyrido[2,3-d]pyrimidine.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20120401

• Release of NO from a nitrosyl ruthenium complex through oxidation of mitochondrial NADH and effects on mitochondria.

  Nitric oxide : biology and chemistry 20120331

• Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.

  The Journal of biological chemistry 20120330

• Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20120319

• The role of reactive oxygen species in the modulation of the contraction induced by angiotensin II in carotid artery from diabetic rat.

  European journal of pharmacology 20120305

• Studies with low micromolar levels of ascorbic and dehydroascorbic acid fail to unravel a preferential route for vitamin C uptake and accumulation in U937 cells.

  The British journal of nutrition 20120301

• Aloe vera juice: IC₅₀ and dual mechanistic inhibition of CYP3A4 and CYP2D6.

  Phytotherapy research : PTR 20120301

• Spironolactone improves nephropathy by enhancing glucose-6-phosphate dehydrogenase activity and reducing oxidative stress in diabetic hypertensive rat.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

• Novel iron-sulfur containing NADPH-reductase from Nocardia farcinica IFM10152 and fusion construction with CYP51 lanosterol demethylase.

  Biotechnology and bioengineering 20120301

• Identification and functional characterization of two novel mutations in the α-helical loop (residues 484-503) of CYBB/gp91(phox) resulting in the rare X91(+) variant of chronic granulomatous disease.

  Human mutation 20120301

• Inhibition of NADPH oxidase activation by peptides mapping within the dehydrogenase region of Nox2-A 'peptide walking' study.

  Journal of leukocyte biology 20120301

• Placental TonEBP/NFAT5 osmolyte regulation in an ovine model of intrauterine growth restriction.

  Biology of reproduction 20120301

• Silencing of nicotinamide nucleotide transhydrogenase impairs cellular redox homeostasis and energy metabolism in PC12 cells.

  Biochimica et biophysica acta 20120301

• In vivo detection of glutathione disulfide and oxidative stress monitoring using a biosensor.

  Biomaterials 20120301

• Prevention of salt-induced renal injury by activation of NAD(P)H:quinone oxidoreductase 1, associated with NADPH oxidase.

  Free radical biology & medicine 20120301

• Uptake and incorporation of iron in sugar beet chloroplasts.

  Plant physiology and biochemistry : PPB 20120301

• Evaluation of time-dependent cytochrome p450 inhibition in a high-throughput, automated assay: introducing a novel area under the curve shift approach.

  Drug metabolism letters 20120301

• [Nicorandil and ulceration: a physiopathological hypothesis].

  Annales de dermatologie et de venereologie 20120301

• A microchamber array for single cell isolation and analysis of intracellular biomolecules.

  Lab on a chip 20120221

• Inhibition of cytochrome p450 enzymes by quinones and anthraquinones.

  Chemical research in toxicology 20120220

• Unusual NADPH conformation in the crystal structure of a cinnamyl alcohol dehydrogenase from Helicobacter pylori in complex with NADP(H) and substrate docking analysis.

  FEBS letters 20120217

• Metabolic activation of sulfur mustard leads to oxygen free radical formation.

  Free radical biology & medicine 20120215

• Engineered NADH-dependent GRE2 from Saccharomyces cerevisiae by directed enzyme evolution enhances HMF reduction using additional cofactor NADPH.

  Enzyme and microbial technology 20120210

• Caffeine inhibits erythrocyte membrane derangement by antioxidant activity and by blocking caspase 3 activation.

  Biochimie 20120201

• Photosystem I from plants as a bacterial cytochrome P450 surrogate electron donor: terminal hydroxylation of branched hydrocarbon chains.

  Biotechnology letters 20120201

• AMPK-mediated increase of glycolysis as an adaptive response to oxidative stress in human cells: implication of the cell survival in mitochondrial diseases.

  Biochimica et biophysica acta 20120201

• Engineering yield and rate of reductive biotransformation in Escherichia coli by partial cyclization of the pentose phosphate pathway and PTS-independent glucose transport.

  Applied microbiology and biotechnology 20120201

• Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP.

  Human molecular genetics 20120201

• Reduced neuronal expression of ribose-5-phosphate isomerase enhances tolerance to oxidative stress, extends lifespan, and attenuates polyglutamine toxicity in Drosophila.

  Aging cell 20120201

• Circadian feeding drive of metabolic activity in adipose tissue and not hyperphagia triggers overweight in mice: is there a role of the pentose-phosphate pathway?

  Endocrinology 20120201

• Arachidonic acid mobilizes Ca2+ from the endoplasmic reticulum and an acidic store in rat pancreatic β cells.

  Cell calcium 20120201

• Mode change in the self-motion of a benzoquinone disk coupled with a NADPH system.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20120201

• Dihydrophenanthridine: a new and easily regenerable NAD(P)H model for biomimetic asymmetric hydrogenation.

  Journal of the American Chemical Society 20120201

• Triggering of Ca2+ signals by NAADP-gated two-pore channels: a role for membrane contact sites?

  Biochemical Society transactions 20120201

• Structural studies on Mycobacterium tuberculosis DXR in complex with the antibiotic FR-900098.

  Acta crystallographica. Section D, Biological crystallography 20120201

• Aliphatic esters as targets of esterase activity in the parsnip webworm (Depressaria pastinacella).

  Journal of chemical ecology 20120201

• Purification and characterization of a thermostable glutamate dehydrogenase from a thermophilic bacterium isolated from a sterilization drying oven.

  BMB reports 20120201

• Induction of biogenic magnetization and redox control by a component of the target of rapamycin complex 1 signaling pathway.

  PLoS biology 20120201

• Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin egg.

  The Journal of biological chemistry 20120120

• Reductive carboxylation supports growth in tumour cells with defective mitochondria.

  Nature 20120119

• Inhibition of the MUC1-C oncoprotein induces multiple myeloma cell death by down-regulating TIGAR expression and depleting NADPH.

  Blood 20120119

• Functional screening of cytochrome P450 activity and uncoupling by capillary electrophoresis.

  Analytical chemistry 20120117

• The potential of biodetoxification activity as a probiotic property of Lactobacillus reuteri.

  International journal of food microbiology 20120116

• Metabolic development in the liver and the implications of the n-3 fatty acid supply.

  American journal of physiology. Gastrointestinal and liver physiology 20120115

• Photoregulation of cytochrome P450 activity by using caged compound.

  Analytical chemistry 20120103

• Application of a novel thermostable NAD(P)H oxidase from hyperthermophilic archaeon for the regeneration of both NAD⁺ and NADP⁺.

  Biotechnology and bioengineering 20120101

• Pyruvate incubation enhances glycogen stores and sustains neuronal function during subsequent glucose deprivation.

  Neurobiology of disease 20120101

• Redox imbalance in rat tissues exposed with organophosphate pesticides and therapeutic potential of antioxidant vitamins.

  Ecotoxicology and environmental safety 20120101

• A combined biochemical screen and TILLING approach identifies mutations in Sorghum bicolor L. Moench resulting in acyanogenic forage production.

  Plant biotechnology journal 20120101

• NAADP regulates human platelet function.

  The Biochemical journal 20120101

• Domain assembly of NAADP-gated two-pore channels.

  The Biochemical journal 20120101

• Discovering the role of mitochondria in the iron deficiency-induced metabolic responses of plants.

  Journal of plant physiology 20120101

• Integration of in vivo and in silico metabolic fluxes for improvement of recombinant protein production.

  Metabolic engineering 20120101

• Effect of histidine-tag and R457H and E580Q mutations on catalytic activity of recombinant human cytochrome P450 oxidoreductase.

  Drug metabolism and pharmacokinetics 20120101

• Differential roles of NADPH oxidases in vascular physiology and pathophysiology.

  Frontiers in bioscience (Scholar edition) 20120101

• Cardiovascular antioxidant therapy: a review of supplements, pharmacotherapies, and mechanisms.

  Cardiology in review 20120101

• Activation of CD40 with platelet derived CD154 promotes reactive oxygen species dependent death of human hepatocytes during hypoxia and reoxygenation.

  PloS one 20120101

• Functional expression and characterization of recombinant NADPH-P450 reductase from Malassezia globosa.

  Journal of microbiology and biotechnology 20120101

• Mechanism-based inhibition of recombinant human cytochrome P450 3A4 by tomato juice extract.

  Biological & pharmaceutical bulletin 20120101

• Functional characterization of allelic variants of polymorphic human cytochrome P450 2A6 (CYP2A6*5, *7, *8, *18, *19, and *35).

  Biological & pharmaceutical bulletin 20120101

• The mitochondrial alternative oxidase pathway protects the photosynthetic apparatus against photodamage in Rumex K-1 leaves.

  BMC plant biology 20120101

• Chemical mechanism of UDP-galactopyranose mutase from Trypanosoma cruzi: a potential drug target against Chagas' disease.

  PloS one 20120101

• Monitoring the reductive and oxidative half-reactions of a flavin-dependent monooxygenase using stopped-flow spectrophotometry.

  Journal of visualized experiments : JoVE 20120101

• Pyridine nucleotide metabolites and calcium release from intracellular stores.

  Advances in experimental medicine and biology 20120101

• Artificial leaf device for solar fuel production.

  Faraday discussions 20120101

• A novel enzymatic system against oxidative stress in the thermophilic hydrogen-oxidizing bacterium Hydrogenobacter thermophilus.

  PloS one 20120101

• Involvement of actin filament in the generation of Ca2+ mobilizing messengers in glucose-induced Ca2+ signaling in pancreatic β-cells.

  Islets 20120101

• Effect of ADH II deficiency on the intracellular redox homeostasis in Zymomonas mobilis.

  TheScientificWorldJournal 20120101

• [Peculiar properties of glutathione system and NADPH-generated enzymes functioning in blood of patients with drug-induced hepatitis under combined treatment with epifamin].

  Biomeditsinskaia khimiia 20120101

• Differential effects of polyamine on the cytosolic and mitochondrial NADP-isocitrate dehydrogenases.

  BioFactors (Oxford, England) 20120101

• Comparative analysis on the key enzymes of the glycerol cycle metabolic pathway in Dunaliella salina under osmotic stresses.

  PloS one 20120101

• A novel reductase from Candida albicans for the production of ethyl (S)-4-chloro-3-hydroxybutanoate.

  Bioscience, biotechnology, and biochemistry 20120101

• A comparative transcriptomic, fluxomic and metabolomic analysis of the response of Saccharomyces cerevisiae to increases in NADPH oxidation.

  BMC genomics 20120101

• Detailed analysis of apoptosis and delayed luminescence of human leukemia Jurkat T cells after proton irradiation and treatments with oxidant agents and flavonoids.

  Oxidative medicine and cellular longevity 20120101

• Benzofuran derivatives inhibit 11β-hydroxysteroid dehydrogenase type 1 activity in rat adipose tissue.

  Biological & pharmaceutical bulletin 20120101

• Monoterpene alcohol metabolism: identification, purification, and characterization of two geraniol dehydrogenase isoenzymes from Polygonum minus leaves.

  Bioscience, biotechnology, and biochemistry 20120101

• Characterization of genes involved in D-sorbitol oxidation in thermotolerant Gluconobacter frateurii.

  Bioscience, biotechnology, and biochemistry 20120101

• Glucose is a pH-dependent motor for sperm beat frequency during early activation.

  PloS one 20120101

• Regulation of the cyanobacterial CO2-concentrating mechanism involves internal sensing of NADP+ and α-ketogutarate levels by transcription factor CcmR.

  PloS one 20120101

• Comparative molecular modeling study of Arabidopsis NADPH-dependent thioredoxin reductase and its hybrid protein.

  PloS one 20120101

• The Pictet-Spengler mechanism involved in the biosynthesis of tetrahydroisoquinoline antitumor antibiotics: a novel function for a nonribosomal peptide synthetase.

  Methods in enzymology 20120101

• Co-factor binding confers substrate specificity to xylose reductase from Debaryomyces hansenii.

  PloS one 20120101

• Glucose-6-phosphate dehydrogenase and NADPH redox regulates cardiac myocyte L-type calcium channel activity and myocardial contractile function.

  PloS one 20120101

• A hydrazine coupled cycling assay validates the decrease in redox ratio under starvation in Drosophila.

  PloS one 20120101

• Tryptophan 697 modulates hydride and interflavin electron transfer in human methionine synthase reductase.

  Biochemistry 20111227

• Direct redox regulation of F-actin assembly and disassembly by Mical.

  Science (New York, N.Y.) 20111223

• Catalytic activity of selenomethionine in removing amino acid, peptide, and protein hydroperoxides.

  Free radical biology & medicine 20111215

• Enhanced screening of glutathione-trapped reactive metabolites by in-source collision-induced dissociation and extraction of product ion using UHPLC-high resolution mass spectrometry.

  Analytical chemistry 20111215

• Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair.

  The Journal of biological chemistry 20111202

• Kinetic and optical biosensor study of adrenodoxin mutant AdxS112W displaying an enhanced interaction towards the cholesterol side chain cleavage enzyme (CYP11A1).

  European biophysics journal : EBJ 20111201

• Identification of a xylose reductase gene in the xylose metabolic pathway of Kluyveromyces marxianus NBRC1777.

  Journal of industrial microbiology & biotechnology 20111201

• Increased NADPH availability in Escherichia coli: improvement of the product per glucose ratio in reductive whole-cell biotransformation.

  Applied microbiology and biotechnology 20111201

• Engineering the pentose phosphate pathway to improve hydrogen yield in recombinant Escherichia coli.

  Biotechnology and bioengineering 20111201

• Luteolin protects osteoblastic MC3T3-E1 cells from antimycin A-induced cytotoxicity through the improved mitochondrial function and activation of PI3K/Akt/CREB.

  Toxicology in vitro : an international journal published in association with BIBRA 20111201

• Mechanistic and structural studies of the N-hydroxylating flavoprotein monooxygenases.

  Bioorganic chemistry 20111201

• Kinetic mechanism of an aldehyde reductase of Saccharomyces cerevisiae that relieves toxicity of furfural and 5-hydroxymethylfurfural.

  Biochimica et biophysica acta 20111201

• Aromatic interactions at atom-to-atom contact and just beyond: a case study of protein interactions of NAD⁺/NADP⁺.

  International journal of biological macromolecules 20111201

• Characterization of an oxidoreductase from the arylamine N-acetyltransferase operon in Mycobacterium smegmatis.

  The FEBS journal 20111201

• WldS enhances insulin transcription and secretion via a SIRT1-dependent pathway and improves glucose homeostasis.

  Diabetes 20111201

• Role of mitochondrial NADH kinase and NADPH supply in the respiratory chain activity of Saccharomyces cerevisiae.

  Acta biochimica et biophysica Sinica 20111201

• Cofactor mobility determines reaction outcome in the IMPDH and GMPR (β-α)8 barrel enzymes.

  Nature chemical biology 20111201

• Substituted derivatives of indole acetic acid as aldose reductase inhibitors with antioxidant activity: structure-activity relationship.

  General physiology and biophysics 20111201

• Coupled motions direct electrons along human microsomal P450 Chains.

  PLoS biology 20111201

• Chemical and enzymatic reductive activation of acylfulvene to isomeric cytotoxic reactive intermediates.

  Chemical research in toxicology 20111121

• CD38: a NAADP degrading enzyme.

  FEBS letters 20111116

• Identification of endogenous ligands bound to bacterially expressed human and E. coli dihydrofolate reductase by 2D NMR.

  FEBS letters 20111116

• Influence of heme-thiolate in shaping the catalytic properties of a bacterial nitric-oxide synthase.

  The Journal of biological chemistry 20111111

• Novel NADPH-cysteine covalent adduct found in the active site of an aldehyde dehydrogenase.

  The Biochemical journal 20111101

• Gold nanoparticle penetration and reduced metabolism in human skin by toluene.

  Pharmaceutical research 20111101

• Alignment of sarcoplasmic reticulum-mitochondrial junctions with mitochondrial contact points.

  American journal of physiology. Heart and circulatory physiology 20111101

• Molecular and biochemical characterisation of a Teladorsagia circumcincta glutamate dehydrogenase.

  Experimental parasitology 20111101

• NAADP influences excitation-contraction coupling by releasing calcium from lysosomes in atrial myocytes.

  Cell calcium 20111101

• NOX2 activated by α1-adrenoceptors modulates hepatic metabolic routes stimulated by β-adrenoceptors.

  Free radical research 20111101

• NADPH-dependent pgi-gene knockout Escherichia coli metabolism producing shikimate on different carbon sources.

  FEMS microbiology letters 20111101

• Identification of biochemical network modules based on shortest retroactive distances.

  PLoS computational biology 20111101

• Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats.

  Journal of biomedical optics 20111101

• Dl-α-tocopherol enhances the herbicide 1,1'-dimetyl-4,4'-bipyridium dichloride (paraquat, PQ) genotoxicity in cultured anuran leukocytes.

  Hereditas 20111101

• [Effect of enhanced UV-B radiation on metabolism and berberine content of Coptis chinensis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111101

• Two-pore channels form homo- and heterodimers.

  The Journal of biological chemistry 20111028

• Employing modular polyketide synthase ketoreductases as biocatalysts in the preparative chemoenzymatic syntheses of diketide chiral building blocks.

  Chemistry & biology 20111028

• Novel mechanism for dehalogenation and glutathione conjugation of dihalogenated anilines in human liver microsomes: evidence for ipso glutathione addition.

  Chemical research in toxicology 20111017

• A QM/MM-based computational investigation on the catalytic mechanism of saccharopine reductase.

  Molecules (Basel, Switzerland) 20111012

• Engineering the respiratory complex I to energy-converting NADPH:ubiquinone oxidoreductase.

  The Journal of biological chemistry 20111007

• Endogenous reactive oxygen species content and modulation of tyrosine phosphorylation during sperm capacitation.

  International journal of andrology 20111001

• Redox state and energetic equilibrium determine the magnitude of stress in Hydrilla verticillata upon exposure to arsenate.

  Protoplasma 20111001

• Inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica.

  Parasitology research 20111001

• Microsomal oxidative damage promoted by acetaminophen metabolism.

  Toxicology in vitro : an international journal published in association with BIBRA 20111001

• Mitochondria-localized NAD biosynthesis by nicotinamide mononucleotide adenylyltransferase in Jerusalem artichoke (Helianthus tuberosus L.) heterotrophic tissues.

  Planta 20111001

• cGMP regulates hydrogen peroxide accumulation in calcium-dependent salt resistance pathway in Arabidopsis thaliana roots.

  Planta 20111001

• A tricistronic human adrenodoxin reductase-adrenodoxin-cytochrome P450 27A1 vector system for substrate hydroxylation in Escherichia coli.

  Protein expression and purification 20111001

• The characterization of a unique Trypanosoma brucei β-hydroxybutyrate dehydrogenase.

  Molecular and biochemical parasitology 20111001

• Acute renal failure associated to paroxysmal nocturnal haemoglobinuria leads to intratubular haemosiderin accumulation and CD163 expression.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111001

• Beneficial role of Nrf2 in regulating NADPH generation and consumption.

  Toxicological sciences : an official journal of the Society of Toxicology 20111001

• Male Sterile2 encodes a plastid-localized fatty acyl carrier protein reductase required for pollen exine development in Arabidopsis.

  Plant physiology 20111001

• Structural insights into the cofactor-assisted substrate recognition of yeast quinone oxidoreductase Zta1.

  Journal of structural biology 20111001

• Regulation of NAD(P)H dehydrogenase-dependent cyclic electron transport around PSI by NaHSO₃ at low concentrations in tobacco chloroplasts.

  Plant & cell physiology 20111001

• Purification and biochemical characterization of a moderately halotolerant NADPH dependent xylose reductase from Debaryomyces nepalensis NCYC 3413.

  Bioresource technology 20111001

• The rate of ATP export in the extramitochondrial phase via the adenine nucleotide translocator changes in aging in mitochondria isolated from heart left ventricle of either normotensive or spontaneously hypertensive rats.

  Mechanisms of ageing and development 20111001

• Structure of a highly NADP+-specific isocitrate dehydrogenase.

  Acta crystallographica. Section D, Biological crystallography 20111001

• Interplay between non-photochemical plastoquinone reduction and re-oxidation in pre-illuminated Chlamydomonas reinhardtii: a chlorophyll fluorescence study.

  Photosynthesis research 20111001

• Antioxidant properties of pioglitazone limit nicotinamide adenine dinucleotide phosphate hydrogen oxidase and augment superoxide dismutase activity in cardiac allotransplantation.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20111001

• Biochemical properties and physiological roles of NADP-dependent malic enzyme in Escherichia coli.

  Journal of microbiology (Seoul, Korea) 20111001

• Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK).

  The Journal of biological chemistry 20110923

• Rapid and quantitative measurement of metabolic stability without chromatography or mass spectrometry.

  Journal of the American Chemical Society 20110921

• Quantifying the dynamics of bacterial secondary metabolites by spectral multiphoton microscopy.

  ACS chemical biology 20110916

• The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels.

  Cancer cell 20110913

• Two structures of an N-hydroxylating flavoprotein monooxygenase: ornithine hydroxylase from Pseudomonas aeruginosa.

  The Journal of biological chemistry 20110909

• NOX1/nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase promotes proliferation of stellate cells and aggravates liver fibrosis induced by bile duct ligation.

  Hepatology (Baltimore, Md.) 20110902

• Stimulatory effects of calcium on respiration and NAD(P)H synthesis in intact rat heart mitochondria utilizing physiological substrates cannot explain respiratory control in vivo.

  The Journal of biological chemistry 20110902

• Real-time measurements of nicotinamide adenine dinucleotide in live human trabecular meshwork cells: effects of acute oxidative stress.

  Experimental eye research 20110901

• A marriage full of surprises: forty-five years living with glutamate dehydrogenase.

  Neurochemistry international 20110901

• NADPH regulates human NAD kinase, a NADP⁺-biosynthetic enzyme.

  Molecular and cellular biochemistry 20110901

• Methylglyoxal functions as Hill oxidant and stimulates the photoreduction of O(2) at photosystem I: a symptom of plant diabetes.

  Plant, cell & environment 20110901

• Enzymatic characterization of isocitrate dehydrogenase from an emerging zoonotic pathogen Streptococcus suis.

  Biochimie 20110901

• Activation of aldo-keto reductase family member 1B14 (AKR1B14) by bile acids: Activation mechanism and bile acid-binding site.

  Biochimie 20110901

• Nicotinamide adenine dinucleotide phosphate/neuronal nitric oxide synthase-positive neurons in the trigeminal subnucleus caudalis involved in tooth pulp nociception.

  Journal of neuroscience research 20110901

• Intracellular angiotensin II activates rat myometrium.

  American journal of physiology. Cell physiology 20110901

• Sequential metabolism of sesamin by cytochrome P450 and UDP-glucuronosyltransferase in human liver.

  Drug metabolism and disposition: the biological fate of chemicals 20110901

• In vitro characterization of the metabolic pathways and cytochrome P450 inhibition and induction potential of BMS-690514, an ErbB/vascular endothelial growth factor receptor inhibitor.

  Drug metabolism and disposition: the biological fate of chemicals 20110901

• Biochemical and genetic characterization of the three metabolic routes in Thermococcus kodakarensis linking glyceraldehyde 3-phosphate and 3-phosphoglycerate.

  Molecular microbiology 20110901

• A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis.

  The FEBS journal 20110901

• A larger transcript is required for the synthesis of the smaller isoform of ferredoxin:NADP oxidoreductase.

  Molecular microbiology 20110901

• Essential role of tissue-specific proline synthesis and catabolism in growth and redox balance at low water potential.

  Plant physiology 20110901

• A switching mechanism in doxorubicin bioactivation can be exploited to control doxorubicin toxicity.

  PLoS computational biology 20110901

• Postnatal development of nitrergic and cholinergic structures in rat spinal cord.

  Archives italiennes de biologie 20110901

• Chemically engineered papain as artificial formate dehydrogenase for NAD(P)H regeneration.

  Organic & biomolecular chemistry 20110821

• NADH oxidase activity of indoleamine 2,3-dioxygenase.

  The Journal of biological chemistry 20110819

• Snapshots of enzymatic Baeyer-Villiger catalysis: oxygen activation and intermediate stabilization.

  The Journal of biological chemistry 20110819

• Structure and nucleotide specificity of Staphylococcus aureus dihydrodipicolinate reductase (DapB).

  FEBS letters 20110819

• Catalytic mechanism and cofactor preference of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus.

  Archives of biochemistry and biophysics 20110815

• A new amperometric bienzymatic biosensor based on biocomposites for the determination of gluconic acid in wines.

  Talanta 20110815

• Cytochromes P450 catalyze the reduction of α,β-unsaturated aldehydes.

  Chemical research in toxicology 20110815

• Pyrazinamide, but not pyrazinoic acid, is a competitive inhibitor of NADPH binding to Mycobacterium tuberculosis fatty acid synthase I.

  Bioorganic & medicinal chemistry letters 20110815

• Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution.

  Nature chemistry 20110814

• FAD-binding site and NADP reactivity in human renalase: a new enzyme involved in blood pressure regulation.

  Journal of molecular biology 20110812

• Improving ethanol productivity by modification of glycolytic redox factor generation in glycerol-3-phosphate dehydrogenase mutants of an industrial ethanol yeast.

  Journal of industrial microbiology & biotechnology 20110801

• Increasing fatty acid production in E. coli by simulating the lipid accumulation of oleaginous microorganisms.

  Journal of industrial microbiology & biotechnology 20110801

• Alternative photosynthetic electron transport pathways during anaerobiosis in the green alga Chlamydomonas reinhardtii.

  Biochimica et biophysica acta 20110801

• The plant vacuole: emitter and receiver of calcium signals.

  Cell calcium 20110801

• Aberrant Ca(2+) signalling through acidic calcium stores in pancreatic acinar cells.

  Cell calcium 20110801

• Involvement of PI3K/Akt/CREB and redox changes in mitochondrial defect of osteoblastic MC3T3-E1 cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20110801

• Computational analysis of storage synthesis in developing Brassica napus L. (oilseed rape) embryos: flux variability analysis in relation to ¹³C metabolic flux analysis.

  The Plant journal : for cell and molecular biology 20110801

• Metabolic network reconstruction and flux variability analysis of storage synthesis in developing oilseed rape (Brassica napus L.) embryos.

  The Plant journal : for cell and molecular biology 20110801

• Enhanced production of GDP-L-fucose by overexpression of NADPH regenerator in recombinant Escherichia coli.

  Applied microbiology and biotechnology 20110801

• Role of residue 87 in substrate selectivity and regioselectivity of drug-metabolizing cytochrome P450 CYP102A1 M11.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20110801

• Metabolite modulation of HeLa cell response to ENOX2 inhibitors EGCG and phenoxodiol.

  Biochimica et biophysica acta 20110801

• Kinetic analysis of reactive oxygen species generated by the in vitro reconstituted NADPH oxidase and xanthine oxidase systems.

  Journal of biochemistry 20110801

• Acidic NAADP-releasable Ca(2+) compartments in the megakaryoblastic cell line MEG01.

  Biochimica et biophysica acta 20110801

• Reconstitution of lysosomal NAADP-TRP-ML1 signaling pathway and its function in TRP-ML1(-/-) cells.

  American journal of physiology. Cell physiology 20110801

• Human liver enzymes responsible for metabolic elimination of tyramine; a vasopressor agent from daily food.

  Drug metabolism letters 20110801

• Lysosomal Ca(2+) homeostasis: role in pathogenesis of lysosomal storage diseases.

  Cell calcium 20110801

• Cyclic ADP-ribose and NAADP: fraternal twin messengers for calcium signaling.

  Science China. Life sciences 20110801

• Physiological roles of NAADP-mediated Ca2+ signaling.

  Science China. Life sciences 20110801

• Triple isotopic labeling and kinetic isotope effects: exposing H-transfer steps in enzymatic systems.

  Biochemistry 20110726

• NAADP mediates ATP-induced Ca2+ signals in astrocytes.

  FEBS letters 20110721

• The pentose phosphate pathway is a metabolic redox sensor and regulates transcription during the antioxidant response.

  Antioxidants & redox signaling 20110715

• Combined structural and functional investigation of a C-3''-ketoreductase involved in the biosynthesis of dTDP-L-digitoxose.

  Biochemistry 20110705

• Redox regulation of the mitochondrial K(ATP) channel in cardioprotection.

  Biochimica et biophysica acta 20110701

• Engineering a non-native hydrogen production pathway into Escherichia coli via a cyanobacterial [NiFe] hydrogenase.

  Metabolic engineering 20110701

• Improving the ethanol yield by reducing glycerol formation using cofactor regulation in Saccharomyces cerevisiae.

  Biotechnology letters 20110701

• The anoxic plant mitochondrion as a nitrite: NO reductase.

  Mitochondrion 20110701

• Coupling of 6-phosphogluconate dehydrogenase with NADPH oxidase in neutrophils: Nox2 activity regulation by NADPH availability.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110701

• Effects of acetylenic epoxygenase inhibitors on recombinant cytochrome p450s.

  Drug metabolism and disposition: the biological fate of chemicals 20110701

• Manifold effects of palmitoylcarnitine on endoplasmic reticulum metabolism: 11β-hydroxysteroid dehydrogenase 1, flux through hexose-6-phosphate dehydrogenase and NADPH concentration.

  The Biochemical journal 20110701

• Protective role of cytosolic NADP(+)-dependent isocitrate dehydrogenase, IDH1, in ischemic pre-conditioned kidney in mice.

  Free radical research 20110701

• A difference gel electrophoresis study on thylakoids isolated from poplar leaves reveals a negative impact of ozone exposure on membrane proteins.

  Journal of proteome research 20110701

• Structural and functional analysis of bacterial flavin-containing monooxygenase reveals its ping-pong-type reaction mechanism.

  Journal of structural biology 20110701

• Distinguishing two groups of flavin reductases by analyzing the protonation state of an active site carboxylic acid.

  Proteins 20110701

• Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.

  The Journal of biological chemistry 20110701

• Intestinal transport of scutellarein and scutellarin and first-pass metabolism by UDP-glucuronosyltransferase-mediated glucuronidation of scutellarein and hydrolysis of scutellarin.

  Xenobiotica; the fate of foreign compounds in biological systems 20110701

• Peroxiredoxins and NADPH-dependent thioredoxin systems in the model legume Lotus japonicus.

  Plant physiology 20110701

• Re-engineering the discrimination between the oxidized coenzymes NAD+ and NADP+ in clostridial glutamate dehydrogenase and a thorough reappraisal of the coenzyme specificity of the wild-type enzyme.

  The FEBS journal 20110701

• Phospholipid dependence of the reversible, energy-linked, mitochondrial transhydrogenase in Manduca sexta.

  The Journal of membrane biology 20110701

• [Increasing reductant NADPH content via metabolic engineering of PHB synthesis pathway in Synechocystis sp. PCC 6803].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20110701

• [Effect of controlled overexpression of xylulokinase by different promoters on xylose metabolism in Saccharomyces cerevisiae].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20110701

• Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis.

  Neuroscience 20110630

• Light-driven cytochrome p450 hydroxylations.

  ACS chemical biology 20110617

• Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11β-hydroxysteroid dehydrogenase 1.

  The Biochemical journal 20110615

• Disruption of pyridine nucleotide redox status during oxidative challenge at normal and low-glucose states: implications for cellular adenosine triphosphate, mitochondrial respiratory activity, and reducing capacity in colon epithelial cells.

  Antioxidants & redox signaling 20110601

• Differential effects on inhibition of cholesterol absorption by plant stanol and plant sterol esters in apoE-/- mice.

  Cardiovascular research 20110601

• The kinetic properties of the glutamate dehydrogenase of Teladorsagia circumcincta and their significance for the lifestyle of the parasite.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20110601

• Synthesis and biological evaluation of 2'-oxo-2,3-dihydro-3'H- spiro[chromene-4,5'-[1,3]oxazolidin]-3'yl]acetic acid derivatives as aldose reductase inhibitors.

  Archiv der Pharmazie 20110601

• Balloon catheter injury abolishes phenylephrine-induced relaxation in the rat contralateral carotid.

  British journal of pharmacology 20110601

• Biodiversity in sulfur metabolism in hemiascomycetous yeasts.

  FEMS yeast research 20110601

• Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells.

  Gastroenterology 20110601

• Structure of a NADPH-dependent blue fluorescent protein revealed the unique role of Gly176 on the fluorescence enhancement.

  Journal of structural biology 20110601

• Role of 11β-OH-C(19) and C(21) steroids in the coupling of 11β-HSD1 and 17β-HSD3 in regulation of testosterone biosynthesis in rat Leydig cells.

  Steroids 20110601

• A novel L-aspartate dehydrogenase from the mesophilic bacterium Pseudomonas aeruginosa PAO1: molecular characterization and application for L-aspartate production.

  Applied microbiology and biotechnology 20110601

• Redox chemistry of the Schizosaccharomyces pombe ferredoxin electron-transfer domain and influence of Cys to Ser substitutions.

  Journal of inorganic biochemistry 20110601

• NADPH treatment decreases C6 glioma cell survival by increasing oxidative stress.

  Frontiers in bioscience (Elite edition) 20110601

• Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells.

  Biochimica et biophysica acta 20110601

• Human and rodent aldo-keto reductases from the AKR1B subfamily and their specificity with retinaldehyde.

  Chemico-biological interactions 20110530

• Superoxide is produced by the reduced flavin in mitochondrial complex I: a single, unified mechanism that applies during both forward and reverse electron transfer.

  The Journal of biological chemistry 20110520

• In vitro genotoxicity of danthron and its potential mechanism.

  Mutation research 20110518

• NMR structures of apo L. casei dihydrofolate reductase and its complexes with trimethoprim and NADPH: contributions to positive cooperative binding from ligand-induced refolding, conformational changes, and interligand hydrophobic interactions.

  Biochemistry 20110510

• The activity of barley NADPH-dependent thioredoxin reductase C is independent of the oligomeric state of the protein: tetrameric structure determined by cryo-electron microscopy.

  Biochemistry 20110510

• Thermodynamics and solvent effects on substrate and cofactor binding in Escherichia coli chromosomal dihydrofolate reductase.

  Biochemistry 20110510

• Conformational changes of NADPH-cytochrome P450 oxidoreductase are essential for catalysis and cofactor binding.

  The Journal of biological chemistry 20110506

• DHS-21, a dicarbonyl/L-xylulose reductase (DCXR) ortholog, regulates longevity and reproduction in Caenorhabditis elegans.

  FEBS letters 20110506

• Biochemical characterisation of a NADPH-dependent carbonyl reductase from Neurospora crassa reducing α- and β-keto esters.

  Enzyme and microbial technology 20110506

• NAADP links histamine H1 receptors to secretion of von Willebrand factor in human endothelial cells.

  Blood 20110505

• Mitochondrial matrix calcium is an activating signal for hormone secretion.

  Cell metabolism 20110504

• A genetic overhaul of Saccharomyces cerevisiae 424A(LNH-ST) to improve xylose fermentation.

  Journal of industrial microbiology & biotechnology 20110501

• Synthesis of optically pure S-sulfoxide by Escherichia coli transformant cells coexpressing the P450 monooxygenase and glucose dehydrogenase genes.

  Journal of industrial microbiology & biotechnology 20110501

• An enzymatic photometric assay for 2-deoxyglucose uptake in insulin-responsive tissues and 3T3-L1 adipocytes.

  Analytical biochemistry 20110501

• Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay.

  Free radical biology & medicine 20110501

• Carbon monoxide-releasing molecules protect against ischemia-reperfusion injury during kidney transplantation.

  Kidney international 20110501

• Alteration of reducing powers in an isogenic phosphoglucose isomerase (pgi)-disrupted Escherichia coli expressing NAD(P)-dependent malic enzymes and NADP-dependent glyceraldehyde 3-phosphate dehydrogenase.

  Letters in applied microbiology 20110501

• On the chemical mechanism of succinic semialdehyde dehydrogenase (GabD1) from Mycobacterium tuberculosis.

  Archives of biochemistry and biophysics 20110501

• Involvement of NADPH-dependent and cAMP-PKA sensitive H+ channels in the chorda tympani nerve responses to strong acids.

  Chemical senses 20110501

• Synthesis and evaluation of conformationally restricted inhibitors of aspartate semialdehyde dehydrogenase.

  Molecular bioSystems 20110501

• Characterization of D-galacturonate reductase purified from the psychrophilic yeast species Cryptococcus diffluens.

  Journal of bioscience and bioengineering 20110501

• The relationship between different spectral forms of the protochlorophyllide oxidoreductase complex and the structural organisation of prolamellar bodies isolated from Zea mays.

  Photosynthesis research 20110501

• Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli.

  Metabolic engineering 20110501

• Differential activity of NADPH-producing dehydrogenases renders rodents unsuitable models to study IDH1R132 mutation effects in human glioblastoma.

  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20110501

• Identification and characterization of a pyridoxal reductase involved in the vitamin B6 salvage pathway in Arabidopsis.

  Plant molecular biology 20110501

• Regional distribution of nitrergic neurons in the inner retina of the chicken.

  Visual neuroscience 20110501

• Knockdown of cytosolic NADP(+) -dependent isocitrate dehydrogenase enhances MPP(+) -induced oxidative injury in PC12 cells.

  BMB reports 20110501

• Single and multi-exciton dynamics in aqueous protochlorophyllide aggregates.

  The journal of physical chemistry. A 20110428

• Characterization of short-lived electrophilic metabolites of the anticancer agent laromustine (VNP40101M).

  Chemical research in toxicology 20110418

• Glutathione modulates the toxicity of, but is not a biologically relevant reductant for, the Pseudomonas aeruginosa redox toxin pyocyanin.

  Free radical biology & medicine 20110415

• Critical role for CD38-mediated Ca2+ signaling in thrombin-induced procoagulant activity of mouse platelets and hemostasis.

  The Journal of biological chemistry 20110415

• Molecular mechanism of NADPH-glyceraldehyde-3-phosphate dehydrogenase regulation through the C-terminus of CP12 in Chlamydomonas reinhardtii.

  Biochemistry 20110412

• The crystal structure of l-sorbose reductase from Gluconobacter frateurii complexed with NADPH and l-sorbose.

  Journal of molecular biology 20110408

• A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.

  Science (New York, N.Y.) 20110408

• Reactive oxygen species-induced impairment of endothelium-dependent relaxations in rat aortic rings: protection by methanolic extracts of Phoebe grandis.

  Molecules (Basel, Switzerland) 20110406

• Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits.

  Cardiovascular drugs and therapy 20110401

• Priming of neutrophils and differentiated PLB-985 cells by pathophysiological concentrations of TNF-α is partially oxygen dependent.

  Journal of innate immunity 20110401

• Suppression of mitochondrial NADP(+)-dependent isocitrate dehydrogenase activity enhances curcumin-induced apoptosis in HCT116 cells.

  Free radical research 20110401

• In vitro metabolism of oxymetazoline: evidence for bioactivation to a reactive metabolite.

  Drug metabolism and disposition: the biological fate of chemicals 20110401

• The soxRS response of Escherichia coli can be induced in the absence of oxidative stress and oxygen by modulation of NADPH content.

  Microbiology (Reading, England) 20110401

• Identification, cloning, heterologous expression, and characterization of a NADPH-dependent 7β-hydroxysteroid dehydrogenase from Collinsella aerofaciens.

  Applied microbiology and biotechnology 20110401

• Biotransformation of a novel antimitotic agent, I-387, by mouse, rat, dog, monkey, and human liver microsomes and in vivo pharmacokinetics in mice.

  Drug metabolism and disposition: the biological fate of chemicals 20110401

• Effect of functional groups on antioxidant properties of substituted selenoethers.

  Free radical research 20110401

• Catalytic mechanism of the primary human prostaglandin F2α synthase, aldo-keto reductase 1B1--prostaglandin D2 synthase activity in the absence of NADP(H).

  The FEBS journal 20110401

• A comparative analysis of the NADPH thioredoxin reductase C-2-Cys peroxiredoxin system from plants and cyanobacteria.

  Plant physiology 20110401

• Analysis of the oxidation of short chain alkynes by flavocytochrome P450 BM3.

  Metallomics : integrated biometal science 20110401

• Biohydrogenation from biomass sugar mediated by in vitro synthetic enzymatic pathways.

  Chemistry & biology 20110325

• Evaluation of deuterium labeled and unlabeled bis-methyl glutathione combined with nanoliquid chromatography-mass spectrometry to screen and characterize reactive drug metabolites.

  Chemical research in toxicology 20110321

• Membrane topology of NAADP-sensitive two-pore channels and their regulation by N-linked glycosylation.

  The Journal of biological chemistry 20110318

• Control of hepatic nuclear superoxide production by glucose 6-phosphate dehydrogenase and NADPH oxidase-4.

  The Journal of biological chemistry 20110318

• Cyclic adenosine diphosphate ribose activates ryanodine receptors, whereas NAADP activates two-pore domain channels.

  The Journal of biological chemistry 20110318

• NADPH-dependent reductases involved in the detoxification of reactive carbonyls in plants.

  The Journal of biological chemistry 20110304

• Inhibition of c-Met downregulates TIGAR expression and reduces NADPH production leading to cell death.

  Oncogene 20110303

• Morelloflavone from Garcinia dulcis as a novel biflavonoid inhibitor of HMG-CoA reductase.

  Phytotherapy research : PTR 20110301

• Oxygen activation by P450(cin): Protein and substrate mutagenesis.

  Archives of biochemistry and biophysics 20110301

• Iron and nitrosative metabolism in the Antarctic mollusc Laternula elliptica.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20110301

• Functionalized quantum dots to quantify NADPH and their use for NADP+-dependent biocatalyzed transformations.

  Biotechnology letters 20110301

• Reciprocal regulation of Ca²+-activated outward K+ channels of Pyrus pyrifolia pollen by heme and carbon monoxide.

  The New phytologist 20110301

• Monitoring the intracellular store Ca2+ concentration in agonist-stimulated, intact human platelets by using Fluo-5N.

  Journal of thrombosis and haemostasis : JTH 20110301

• Metabolic networks to combat oxidative stress in Pseudomonas fluorescens.

  Antonie van Leeuwenhoek 20110301

• Improved product-per-glucose yields in P450-dependent propane biotransformations using engineered Escherichia coli.

  Biotechnology and bioengineering 20110301

• The role of Cys-298 in aldose reductase function.

  The Journal of biological chemistry 20110225

• Atomic structure of salutaridine reductase from the opium poppy (Papaver somniferum).

  The Journal of biological chemistry 20110225

• NMR studies of DOXP reductoisomerase and its inhibitor complex.

  Chembiochem : a European journal of chemical biology 20110211

• Comparative genomics of NAD(P) biosynthesis and novel antibiotic drug targets.

  Journal of cellular physiology 20110201

• Identification and characterization of the propanediol utilization protein PduP of Lactobacillus reuteri for 3-hydroxypropionic acid production from glycerol.

  Applied microbiology and biotechnology 20110201

• Biotechnological production of mannitol and its applications.

  Applied microbiology and biotechnology 20110201

• Inherited human gp91phox deficiency is associated with impaired isoprostane formation and platelet dysfunction.

  Arteriosclerosis, thrombosis, and vascular biology 20110201

• NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases.

  Leukemia 20110201

• Methanoferrodoxin represents a new class of superoxide reductase containing an iron-sulfur cluster.

  The FEBS journal 20110201

• Modulation of the activity of the NADPH oxidase system by reactive oxygen species: influence of catalase.

  Radiation protection dosimetry 20110201

• Inhibitory effect of rosiglitazone on the acid-induced intracellular generation of hydrogen peroxide in cultured feline esophageal epithelial cells.

  Naunyn-Schmiedeberg's archives of pharmacology 20110201

• Benzocaine-induced methaemoglobinaemia: a case study.

  British journal of nursing (Mark Allen Publishing) 20110201

• Kinetic and chemical mechanism of the dihydrofolate reductase from Mycobacterium tuberculosis.

  Biochemistry 20110125

• Characterization of an NADH-dependent persulfide reductase from Shewanella loihica PV-4: implications for the mechanism of sulfur respiration via FAD-dependent enzymes.

  Biochemistry 20110118

• Simultaneous measurement of CYP1A2 activity, regioselectivity, and coupling: Implications for environmental sensitivity of enzyme-substrate binding.

  Archives of biochemistry and biophysics 20110115

• Structure of rat aldose reductase-like protein AKR1B14 holoenzyme: Probing the role of His269 in coenzyme binding by site-directed mutagenesis.

  Bioorganic & medicinal chemistry letters 20110115

• FdC1, a novel ferredoxin protein capable of alternative electron partitioning, increases in conditions of acceptor limitation at photosystem I.

  The Journal of biological chemistry 20110107

• Metabolic flux analysis of CHO cell metabolism in the late non-growth phase.

  Biotechnology and bioengineering 20110101

• The specificity of proton-translocating transhydrogenase for nicotinamide nucleotides.

  Biochimica et biophysica acta 20110101

• Cytosolic NADPH balancing in Penicillium chrysogenum cultivated on mixtures of glucose and ethanol.

  Applied microbiology and biotechnology 20110101

• Effects of selenite and chelating agents on mammalian thioredoxin reductase inhibited by mercury: implications for treatment of mercury poisoning.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110101

• The NADPH-cytochrome P450 reductase family in Trypanosoma cruzi is involved in the sterol biosynthesis pathway.

  International journal for parasitology 20110101

• Understanding uncoupling in the multiredox centre P450 3A4-BMR model system.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20110101

• In vitro metabolism, glutathione conjugation, and CYP isoform specificity of epoxidation of 4-vinylphenol.

  Xenobiotica; the fate of foreign compounds in biological systems 20110101

• An analytical model of non-photorespiratory CO₂release in the light and dark in leaves of C₃species based on stoichiometric flux balance.

  Plant, cell & environment 20110101

• Quantitating carbon monoxide production from heme by vascular plant preparations in vitro.

  Plant physiology and biochemistry : PPB 20110101

• The importance of energy balance in improving photosynthetic productivity.

  Plant physiology 20110101

• Comparative studies on the biochemical properties of the malic enzymes from Trypanosoma cruzi and Trypanosoma brucei.

  FEMS microbiology letters 20110101

• Structure of recombinant Leishmania donovani pteridine reductase reveals a disordered active site.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20110101

• Structural analysis of Pneumocystis carinii and human DHFR complexes with NADPH and a series of five potent 6-[5'-(ω-carboxyalkoxy)benzyl]pyrido[2,3-d]pyrimidine derivatives.

  Acta crystallographica. Section D, Biological crystallography 20110101

• Improved NADPH supply for xylitol production by engineered Escherichia coli with glycolytic mutations.

  Biotechnology progress 20110101

• [Changes of redox processes in liver under pv-88 at experimental hemorrhagic shock].

  Georgian medical news 20110101

• Proteopedia entry: HMG-CoA reductase.

  Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 20110101

• WWOX oxidoreductase--substrate and enzymatic characterization.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20110101

• Rehab of NAD(P)-dependent enzymes with NAD(P)-based inhibitors.

  Current medicinal chemistry 20110101

• (-)-Epigallocatechin gallate attenuates NADPH-d/nNOS expression in motor neurons of rats following peripheral nerve injury.

  BMC neuroscience 20110101

• Biochemical comparison of Anopheles gambiae and human NADPH P450 reductases reveals different 2'-5'-ADP and FMN binding traits.

  PloS one 20110101

• Intimal hyperplasia in balloon dilated coronary arteries is reduced by local delivery of the NO donor, SIN-1 via a cGMP-dependent pathway.

  BMC cardiovascular disorders 20110101

• Selenite reduction by the thioredoxin system: kinetics and identification of protein-bound selenide.

  Bioscience, biotechnology, and biochemistry 20110101

• Inhibitory effect of metformin on oxidation of NADH-dependent substrates in rat liver homogenate.

  Physiological research 20110101

• Exposure of Candida to p-anisaldehyde inhibits its growth and ergosterol biosynthesis.

  The Journal of general and applied microbiology 20110101

• Calreticulin inhibits prion protein PrP-(23-98) aggregation in vitro.

  Bioscience, biotechnology, and biochemistry 20110101

• A non-NadB type L-aspartate dehydrogenase from Ralstonia eutropha strain JMP134: molecular characterization and physiological functions.

  Bioscience, biotechnology, and biochemistry 20110101

• Phosphonoacetate biosynthesis: in vitro detection of a novel NADP(+)-dependent phosphonoacetaldehyde-oxidizing activity in cell-extracts of the marine Roseovarius nubinhibens ISM.

  Mikrobiologiia 20110101

• [On the importance of a comprehensive study for diagnostics of death from acute ethanol poisoning and coronary heart disease].

  Sudebno-meditsinskaia ekspertiza 20110101

• Purification and characterization of a novel (R)-imine reductase from Streptomyces sp. GF3587.

  Bioscience, biotechnology, and biochemistry 20110101

• Functional properties and substrate characterization of human CYP26A1, CYP26B1, and CYP26C1 expressed by recombinant baculovirus in insect cells.

  Journal of pharmacological and toxicological methods 20110101

• Genome-wide functional profiling reveals genes required for tolerance to benzene metabolites in yeast.

  PloS one 20110101

• Culturing pancreatic islets in microfluidic flow enhances morphology of the associated endothelial cells.

  PloS one 20110101

• Glucose-6-phosphate dehydrogenase protects Escherichia coli from tellurite-mediated oxidative stress.

  PloS one 20110101

• Mitochondrial NAD+-dependent malic enzyme from Anopheles stephensi: a possible novel target for malaria mosquito control.

  Malaria journal 20110101

• Photoactivation studies of zinc porphyrin-myoglobin system and its application for light-chemical energy conversion.

  International journal of biological sciences 20110101

• A novel metagenomic short-chain dehydrogenase/reductase attenuates Pseudomonas aeruginosa biofilm formation and virulence on Caenorhabditis elegans.

  PloS one 20110101

• Protein conjugated with aldehydes derived from lipid peroxidation as an independent parameter of the carbonyl stress in the kidney damage.

  Lipids in health and disease 20110101

• Genome-scale consequences of cofactor balancing in engineered pentose utilization pathways in Saccharomyces cerevisiae.

  PloS one 20110101

• Genome-wide analysis of gene expression during Xenopus tropicalis tadpole tail regeneration.

  BMC developmental biology 20110101

• Bioluminescent enzyme assay for the indication of plant stress in enclosed life support systems.

  Luminescence : the journal of biological and chemical luminescence 20110101

• Isolation and partial characterization of extracellular NADPH-dependent phenol hydroxylase oxidizing phenol to catechol in Comamonas testosteroni.

  Neuro endocrinology letters 20110101

• Identification of two novel reductases involved in equol biosynthesis in Lactococcus strain 20-92.

  Journal of molecular microbiology and biotechnology 20110101

• The effect of active-site isoleucine to alanine mutation on the DHFR catalyzed hydride-transfer.

  Chemical communications (Cambridge, England) 20101221

• Regulation of mitochondrial glutathione redox status and protein glutathionylation by respiratory substrates.

  The Journal of biological chemistry 20101217

• Kinetics of electron transfer between NADPH-cytochrome P450 reductase and cytochrome P450 3A4.

  The Biochemical journal 20101215

• Thermodynamic and NMR analysis of inhibitor binding to dihydrofolate reductase.

  Bioorganic & medicinal chemistry 20101215

• S-RNase disrupts tip-localized reactive oxygen species and induces nuclear DNA degradation in incompatible pollen tubes of Pyrus pyrifolia.

  Journal of cell science 20101215

• Accumulation of true single strand breaks and AP sites in base excision repair deficient cells.

  Mutation research 20101210

• Hyperthermia-induced Hsp90·eNOS preserves mitochondrial respiration in hyperglycemic endothelial cells by down-regulating Glut-1 and up-regulating G6PD activity.

  The Journal of biological chemistry 20101203

• An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signals.

  The Journal of biological chemistry 20101203

• The three-dimensional structure of AKR11B4, a glycerol dehydrogenase from Gluconobacter oxydans, reveals a tryptophan residue as an accelerator of reaction turnover.

  Journal of molecular biology 20101203

• The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes.

  Science (New York, N.Y.) 20101203

• Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia.

  Journal of psychiatric research 20101201

• 8-isoprostane F2α up-regulates the expression of type 5 phosphodiesterase in cavernosal vascular smooth muscle cells: inhibition with sildenafil, iloprost, nitric oxide and picotamide.

  BJU international 20101201

• Cadmium induced mitochondrial redox changes in germinating pea seed.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20101201

• Broadening the cofactor specificity of a thermostable alcohol dehydrogenase using rational protein design introduces novel kinetic transient behavior.

  Biotechnology and bioengineering 20101201

• Dual role of the carboxyl-terminal region of pig liver L-kynurenine 3-monooxygenase: mitochondrial-targeting signal and enzymatic activity.

  Journal of biochemistry 20101201

• The many roles of NOX2 NADPH oxidase-derived ROS in immunity.

  Seminars in immunopathology 20101201

• Structure elucidation of the thermal degradation products of the nucleotide cofactors NADH and NADPH by nano-ESI-FTICR-MS and HPLC-MS.

  Analytical and bioanalytical chemistry 20101201

• Macrophage endoplasmic reticulum (ER) proteins and reducing elements stabilize paraoxonase 2 (PON2).

  Atherosclerosis 20101201

• Brain mitochondria from rats treated with sulforaphane are resistant to redox-regulated permeability transition.

  Journal of bioenergetics and biomembranes 20101201

• Preferential selection of isomer binding from chiral mixtures: alternate binding modes observed for the E and Z isomers of a series of 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines as ternary complexes with NADPH and human dihydrofolate reductase.

  Acta crystallographica. Section D, Biological crystallography 20101201

• High-resolution structures of Trypanosoma brucei pteridine reductase ligand complexes inform on the placement of new molecular entities in the active site of a potential drug target.

  Acta crystallographica. Section D, Biological crystallography 20101201

• Crystallization and preliminary X-ray analysis of 5-keto-D-gluconate reductase from Gluconobacter suboxydans IFO12528 complexed with 5-keto-D-gluconate and NADPH.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20101201

• [Hyperuricemia and metabolic syndrome].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20101201

• NADPH and iron may have an important role in attenuated mucosal defense in Helicobacter pylori infection?

  Mini reviews in medicinal chemistry 20101201

• Analysis of isocitrate dehydrogenase-1/2 gene mutations in gliomas.

  Chinese medical journal 20101201

• Molecular genetics evidence for the in vivo roles of the two major NADPH-dependent disulfide reductases in the malaria parasite.

  The Journal of biological chemistry 20101126

• Acidic NAADP-sensitive calcium stores in the endothelium: agonist-specific recruitment and role in regulating blood pressure.

  The Journal of biological chemistry 20101126

• Focused directed evolution of pentaerythritol tetranitrate reductase by using automated anaerobic kinetic screening of site-saturated libraries.

  Chembiochem : a European journal of chemical biology 20101122

• High-resolution structure of the nitrile reductase QueF combined with molecular simulations provide insight into enzyme mechanism.

  Journal of molecular biology 20101119

• Decreased prereceptorial glucocorticoid activating capacity in starvation due to an oxidative shift of pyridine nucleotides in the endoplasmic reticulum.

  FEBS letters 20101119

• Modeling diauxic glycolytic oscillations in yeast.

  Biophysical journal 20101117

• The photosensitive phs1 mutant is impaired in the riboflavin biogenesis pathway.

  Journal of plant physiology 20101115

• Properties and tissue distribution of a novel aldo-keto reductase encoding in a rat gene (Akr1b10).

  Archives of biochemistry and biophysics 20101115

• Sulfoacetate is degraded via a novel pathway involving sulfoacetyl-CoA and sulfoacetaldehyde in Cupriavidus necator H16.

  The Journal of biological chemistry 20101112

• Nicotinic acid adenine dinucleotide phosphate analogues containing substituted nicotinic acid: effect of modification on Ca(2+) release.

  Journal of medicinal chemistry 20101111

• Binding of reduced nicotinamide adenine dinucleotide phosphate destabilizes the iron−sulfur clusters of human mitoNEET.

  Biochemistry 20101109

• TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+.

  The Journal of biological chemistry 20101105

• Joint functions of protein residues and NADP(H) in oxygen activation by flavin-containing monooxygenase.

  The Journal of biological chemistry 20101105

• Control over enzymatic activity by DNA-directed split enzyme reassembly.

  Chembiochem : a European journal of chemical biology 20101102

• Analysis of glycerol dehydrogenase activities present in Mucor circinelloides YR-1.

  Antonie van Leeuwenhoek 20101101

• Quantitative metabolic flux analysis revealed uneconomical utilization of ATP and NADPH in Acremonium chrysogenum fed with soybean oil.

  Bioprocess and biosystems engineering 20101101

• Regulation of liver glutamate dehydrogenase by reversible phosphorylation in a hibernating mammal.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20101101

• Scale-up of Baeyer-Villiger monooxygenase-catalyzed synthesis of enantiopure compounds.

  Applied microbiology and biotechnology 20101101

• The simultaneous determination of NAD(H) and NADP(H) utilization by glutamate dehydrogenase.

  Molecular and cellular biochemistry 20101101

• Investigating the coenzyme specificity of phenylacetone monooxygenase from Thermobifida fusca.

  Applied microbiology and biotechnology 20101101

• Kallistatin attenuates endothelial apoptosis through inhibition of oxidative stress and activation of Akt-eNOS signaling.

  American journal of physiology. Heart and circulatory physiology 20101101

• The Saccharomyces cerevisiae zinc factor protein Stb5p is required as a basal regulator of the pentose phosphate pathway.

  FEMS yeast research 20101101

• Stereospecificity of the dehydratase domain of the erythromycin polyketide synthase.

  Journal of the American Chemical Society 20101027

• Regulation of NADPH oxidase activity in phagocytes: relationship between FAD/NADPH binding and oxidase complex assembly.

  The Journal of biological chemistry 20101022

• Determinants of substrate binding and protonation in the flavoenzyme xenobiotic reductase A.

  Journal of molecular biology 20101022

• Evidence for the bioactivation of 4-nonylphenol to quinone methide and ortho-benzoquinone metabolites in human liver microsomes.

  Chemical research in toxicology 20101018

• Mapping the catalytic cycle of Schistosoma mansoni thioredoxin glutathione reductase by X-ray crystallography.

  The Journal of biological chemistry 20101015

• Gaining insights into the Bcr-Abl activity-independent mechanisms of resistance to imatinib mesylate in KCL22 cells: a comparative proteomic approach.

  Biochimica et biophysica acta 20101001

• Mild reductions in cytosolic NADP-dependent isocitrate dehydrogenase activity result in lower amino acid contents and pigmentation without impacting growth.

  Amino acids 20101001

• Gene cloning and biochemical characterization of a NAD(P)+ -dependent aldehyde dehydrogenase from Bacillus licheniformis.

  Molecular biotechnology 20101001

• Effects of glucose and insulin on HepG2-C3A cell metabolism.

  Biotechnology and bioengineering 20101001

• A high-throughput screening compatible assay for activators and inhibitors of methionine sulfoxide reductase A.

  Assay and drug development technologies 20101001

• Identification, cloning and characterization of an aldo-keto reductase from Trypanosoma cruzi with quinone oxido-reductase activity.

  Molecular and biochemical parasitology 20101001

• Monitoring mitochondrial electron fluxes using NAD(P)H-flavoprotein fluorometry reveals complex action of isoflurane on cardiomyocytes.

  Biochimica et biophysica acta 20101001

• Characterization of enzymes involved in the central metabolism of Gluconobacter oxydans.

  Applied microbiology and biotechnology 20101001

• Saccharomyces cerevisiae engineered to produce D-xylonate.

  Applied microbiology and biotechnology 20101001

• Dimeric and tetrameric forms of enoyl-acyl carrier protein reductase from Bacillus cereus.

  Biochemical and biophysical research communications 20101001

• Tah18 transfers electrons to Dre2 in cytosolic iron-sulfur protein biogenesis.

  Nature chemical biology 20101001

• Intermediate-dominated controllable biomimetic synthesis of gold nanoparticles in a quasi-biological system.

  Nanoscale 20101001

• Contribution of fructose-6-phosphate to glucocorticoid activation in the endoplasmic reticulum: possible implication in the metabolic syndrome.

  Endocrinology 20101001

• Kenji Soda--researching enzymes with the spirit of an alpinist.

  Journal of biochemistry 20101001

• Multiple metabolic signals influence GAL gene activation by modulating the interaction of Gal80p with the transcriptional activator Gal4p.

  Molecular microbiology 20101001

• Characterization of Deinococcus radiophilus thioredoxin reductase active with both NADH and NADPH.

  Journal of microbiology (Seoul, Korea) 20101001

• Verifying of participation of nitric oxide in morphine place conditioning in the rat medial septum using nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d).

  Iranian biomedical journal 20101001

• Metabolic oxidative stress induced by a combination of 2-DG and 6-AN enhances radiation damage selectively in malignant cells via non-coordinated expression of antioxidant enzymes.

  Cancer letters 20100928

• Metabolic regulation of Drosophila apoptosis through inhibitory phosphorylation of Dronc.

  The EMBO journal 20100915

• Suppressed glucose metabolism in acinar cells might contribute to the development of exocrine pancreatic insufficiency in streptozotocin-induced diabetic mice.

  Metabolism: clinical and experimental 20100901

• Reactive oxygen species formation and cell death in catalase-deficient tobacco leaf disks exposed to cadmium.

  Protoplasma 20100901

• Activation of neuronal nitric oxide synthase in cerebellum of chronic hepatic encephalopathy rats is associated with up-regulation of NADPH-producing pathway.

  Cerebellum (London, England) 20100901

• Role of specific residues in coenzyme binding, charge-transfer complex formation, and catalysis in Anabaena ferredoxin NADP+-reductase.

  Biochimica et biophysica acta 20100901

• Enzymatic-spectrophotometric determination of paraquat in urine samples: a method based on its toxic mechanism.

  Toxicology mechanisms and methods 20100901

• Melatonin enhances antioxidant action of alpha-tocopherol and ascorbate against NADPH- and iron-dependent lipid peroxidation in human placental mitochondria.

  Journal of pineal research 20100901

• Mitochondrial dysfunction induced by different organochalchogens is mediated by thiol oxidation and is not dependent of the classical mitochondrial permeability transition pore opening.

  Toxicological sciences : an official journal of the Society of Toxicology 20100901

• Asymmetric synthesis of (S)-ethyl-4-chloro-3-hydroxy butanoate using a Saccharomyces cerevisiae reductase: enantioselectivity and enzyme-substrate docking studies.

  Biochimica et biophysica acta 20100901

• Functional analysis of the pathways for 2-Cys peroxiredoxin reduction in Arabidopsis thaliana chloroplasts.

  Journal of experimental botany 20100901

• Metabolism and karyotype analysis of oocytes from patients with polycystic ovary syndrome.

  Human reproduction (Oxford, England) 20100901

• Molecular identification of unsaturated uronate reductase prerequisite for alginate metabolism in Sphingomonas sp. A1.

  Biochimica et biophysica acta 20100901

• Integration of a precolumn fluorogenic reaction, separation, and detection of reduced glutathione.

  Analytical chemistry 20100901

• Evidence for the role of oxidative stress in the acetylation of histone H3 by ethanol in rat hepatocytes.

  Alcohol (Fayetteville, N.Y.) 20100901

• Conformation-dependent hydride transfer in neuronal nitric oxide synthase reductase domain.

  The FEBS journal 20100901

• Enantioselective bioconversion using Escherichia coli cells expressing Saccharomyces cerevisiae reductase and Bacillus subtilis glucose dehydrogenase.

  Journal of microbiology and biotechnology 20100901

• Molecular characterization of a class I P450 electron transfer system from Novosphingobium aromaticivorans DSM12444.

  The Journal of biological chemistry 20100827

• Heat shock augments angiotensin II-induced vascular contraction through increased production of reactive oxygen species.

  Biochemical and biophysical research communications 20100827

• Asymmetric dimeric structure of ferredoxin-NAD(P)+ oxidoreductase from the green sulfur bacterium Chlorobaculum tepidum: implications for binding ferredoxin and NADP+.

  Journal of molecular biology 20100820

• High NADPH/NADP+ ratio improves thymidine production by a metabolically engineered Escherichia coli strain.

  Journal of biotechnology 20100820

• Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens.

  Chemical research in toxicology 20100816

• Unexpected hormonal activity of a catechol equine estrogen metabolite reveals reversible glutathione conjugation.

  Chemical research in toxicology 20100816

• Surface-enhanced Raman spectroscopy as a tool for detecting Ca2+ mobilizing second messengers in cell extracts.

  Analytical chemistry 20100815

• Mechanism of inhibition of aliphatic epoxide carboxylation by the coenzyme M analog 2-bromoethanesulfonate.

  The Journal of biological chemistry 20100813

• Aspergillus fumigatus SidA is a highly specific ornithine hydroxylase with bound flavin cofactor.

  Biochemistry 20100810

• Characterization of disease-related 5beta-reductase (AKR1D1) mutations reveals their potential to cause bile acid deficiency.

  The Journal of biological chemistry 20100806

• TPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscle.

  The Journal of biological chemistry 20100806

• Development of an efficient and durable photocatalytic system for hydride reduction of an NAD(P)+ model compound using a ruthenium(II) complex based on mechanistic studies.

  Journal of the American Chemical Society 20100804

• Enantioselective reduction of prochiral ketones by engineered bifunctional fusion proteins.

  Biotechnology and applied biochemistry 20100802

• Zearalenone is bioactivated in the river Buffalo (Bubalus bubalis): hepatic biotransformation.

  Tropical animal health and production 20100801

• Identification of novel metoclopramide metabolites in humans: in vitro and in vivo studies.

  Drug metabolism and disposition: the biological fate of chemicals 20100801

• Redox modulation of Ecto-NOX1 in human platelets.

  Molecular membrane biology 20100801

• Calcium- and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes, but are not the targets for NAADP.

  The Biochemical journal 20100801

• Oxidative stress and inflammation modulate peroxisome proliferator-activated receptors with regional discrepancy in diabetic heart.

  European journal of clinical investigation 20100801

• Glutamine addiction: a new therapeutic target in cancer.

  Trends in biochemical sciences 20100801

• The reaction of NADPH with bovine mitochondrial NADH:ubiquinone oxidoreductase revisited: I. Proposed consequences for electron transfer in the enzyme.

  Journal of bioenergetics and biomembranes 20100801

• The reaction of NADPH with bovine mitochondrial NADH:ubiquinone oxidoreductase revisited: II. Comparison of the proposed working hypothesis with literature data.

  Journal of bioenergetics and biomembranes 20100801

• Nonalcoholic fatty liver disease: detection of elevated nicotinamide adenine dinucleotide phosphate with in vivo 3.0-T 31P MR spectroscopy with proton decoupling.

  Radiology 20100801

• Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases.

  Protein & cell 20100801

• cis-4-decenoic acid provokes mitochondrial bioenergetic dysfunction in rat brain.

  Life sciences 20100731

• An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.

  Journal of natural products 20100723

• Generation of cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate by CD38 for Ca2+ signaling in interleukin-8-treated lymphokine-activated killer cells.

  The Journal of biological chemistry 20100709

• Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism.

  Journal of the National Cancer Institute 20100707

• Metabolic oscillations in pancreatic islets depend on the intracellular Ca2+ level but not Ca2+ oscillations.

  Biophysical journal 20100707

• Coenzyme A-dependent aerobic metabolism of benzoate via epoxide formation.

  The Journal of biological chemistry 20100702

• Midgut and fatbody mitochondrial transhydrogenase activities during larval-pupal development of the tobacco hornworm, Manduca sexta.

  Journal of insect physiology 20100701

• Characterization of a whole-cell catalyst co-expressing glycerol dehydrogenase and glucose dehydrogenase and its application in the synthesis of L-glyceraldehyde.

  Biotechnology and bioengineering 20100701

• Glucose regulates enzymatic sources of mitochondrial NADPH in skeletal muscle cells; a novel role for glucose-6-phosphate dehydrogenase.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100701

• In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity.

  Xenobiotica; the fate of foreign compounds in biological systems 20100701

• Damage to the gastric epithelium activates cellular bicarbonate secretion via SLC26A9 Cl(-)/HCO(3)(-).

  American journal of physiology. Gastrointestinal and liver physiology 20100701

• Characterization of plant carotenoid cyclases as members of the flavoprotein family functioning with no net redox change.

  Plant physiology 20100701

• Nicotinic acid adenine dinucleotide phosphate-mediated calcium signalling in effector T cells regulates autoimmunity of the central nervous system.

  Brain : a journal of neurology 20100701

• A comparative study with colchicine on glutathione reductase.

  The protein journal 20100701

• Glutamate-induced alterations in Ca2+ signaling are modulated by mitochondrial Ca2+ handling capacity in brain slices of R6/1 transgenic mice.

  The European journal of neuroscience 20100701

• Silencing of cytosolic NADP+-dependent isocitrate dehydrogenase gene enhances ethanol-induced toxicity in HepG2 cells.

  Archives of pharmacal research 20100701

• Vitamin E improves learning performance and changes the expression of nitric oxide-producing neurons in the brains of diabetic rats.

  Behavioural brain research 20100626

• Activation of glucose-6-phosphate dehydrogenase promotes acute hypoxic pulmonary artery contraction.

  The Journal of biological chemistry 20100618

• An RNA-directed nucleoside anti-metabolite, 1-(3-C-ethynyl-beta-d-ribo-pentofuranosyl)cytosine (ECyd), elicits antitumor effect via TP53-induced Glycolysis and Apoptosis Regulator (TIGAR) downregulation.

  Biochemical pharmacology 20100615

• Structure and mechanism of sanguinarine reductase, an enzyme of alkaloid detoxification.

  The Journal of biological chemistry 20100611

• The calcium-mobilizing messenger nicotinic acid adenine dinucleotide phosphate participates in sperm activation by mediating the acrosome reaction.

  The Journal of biological chemistry 20100611

• Metabolic and transcriptional response to cofactor perturbations in Escherichia coli.

  The Journal of biological chemistry 20100604

• Identification and functional characterization of a novel mitochondrial carrier for citrate and oxoglutarate in Saccharomyces cerevisiae.

  The Journal of biological chemistry 20100604

• Effect of hexane fraction of leaves of Cinnamomum tamala Linn on macrophage functions.

  Inflammopharmacology 20100601

• Impaired host defence against Mycobacterium avium in mice with chronic granulomatous disease.

  Clinical and experimental immunology 20100601

• Asymmetric synthesis of (S)-3-chloro-1-phenyl-1-propanol using Saccharomyces cerevisiae reductase with high enantioselectivity.

  Applied microbiology and biotechnology 20100601

• Utility of the carboxylesterase inhibitor bis-para-nitrophenylphosphate (BNPP) in the plasma unbound fraction determination for a hydrolytically unstable amide derivative and agonist of the TGR5 receptor.

  Xenobiotica; the fate of foreign compounds in biological systems 20100601

• A functional role for nicotinic acid adenine dinucleotide phosphate in oxytocin-mediated contraction of uterine smooth muscle from rat.

  The Journal of pharmacology and experimental therapeutics 20100601

• Phloridzin: biosynthesis, distribution and physiological relevance in plants.

  Phytochemistry 20100601

• Oxidative stress protection and the repair response to hydrogen peroxide in the hyperthermophilic archaeon Pyrococcus furiosus and in related species.

  Archives of microbiology 20100601

• A single residue in a novel ADP-ribosyl cyclase controls production of the calcium-mobilizing messengers cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate.

  The Journal of biological chemistry 20100601

• Isocitrate dehydrogenase is important for nitrosative stress resistance in Cryptococcus neoformans, but oxidative stress resistance is not dependent on glucose-6-phosphate dehydrogenase.

  Eukaryotic cell 20100601

• Distinct roles of cytochrome P450 reductase in mitomycin C redox cycling and cytotoxicity.

  Molecular cancer therapeutics 20100601

• Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signals.

  Cell calcium 20100601

• The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion.

  The Journal of biological chemistry 20100528

• Candida albicans NADPH-P450 reductase: expression, purification, and characterization of recombinant protein.

  Biochemical and biophysical research communications 20100528

• Disturbance of mitochondrial energy homeostasis caused by the metabolites accumulating in LCHAD and MTP deficiencies in rat brain.

  Life sciences 20100522

• Exposure to chrysotile asbestos causes carbonylation of glucose 6-phosphate dehydrogenase through a reaction with lipid peroxidation products in human lung epithelial cells.

  Toxicology letters 20100519

• Characterization of JadH as an FAD- and NAD(P)H-dependent bifunctional hydroxylase/dehydrase in jadomycin biosynthesis.

  Chembiochem : a European journal of chemical biology 20100517

• Stereospecific reduction of a potent kinesin spindle protein (KSP) inhibitor in human tissues.

  Biochemical pharmacology 20100515

• Glucose suppression of glucagon secretion: metabolic and calcium responses from alpha-cells in intact mouse pancreatic islets.

  The Journal of biological chemistry 20100507

• LICRED: a versatile drop-in vector for rapid generation of redox-self-sufficient cytochrome P450s.

  Chembiochem : a European journal of chemical biology 20100503

• Purification and kinetics of bovine kidney cortex glutathione reductase.

  Protein and peptide letters 20100501

• The cytosolic redox state of astrocytes: Maintenance, regulation and functional implications for metabolite trafficking.

  Brain research reviews 20100501

• Bioactivation of a novel 2-methylindole-containing dual chemoattractant receptor-homologous molecule expressed on T-helper type-2 cells/D-prostanoid receptor antagonist leads to mechanism-based CYP3A inactivation: glutathione adduct characterization and prediction of in vivo drug-drug interaction.

  Drug metabolism and disposition: the biological fate of chemicals 20100501

• In vitro metabolism and identification of human enzymes involved in the metabolism of methylnaltrexone.

  Drug metabolism and disposition: the biological fate of chemicals 20100501

• Lysosome-dependent Ca(2+) release response to Fas activation in coronary arterial myocytes through NAADP: evidence from CD38 gene knockouts.

  American journal of physiology. Cell physiology 20100501

• On the mechanism of oscillations in neutrophils.

  Biophysical chemistry 20100501

• Pathway discovery in metabolic networks by subgraph extraction.

  Bioinformatics (Oxford, England) 20100501

• The short-chain oxidoreductase Q9HYA2 from Pseudomonas aeruginosa PAO1 contains an atypical catalytic center.

  Protein science : a publication of the Protein Society 20100501

• DNA strand cleaving properties and hypoxia-selective cytotoxicity of 7-chloro-2-thienylcarbonyl-3-trifluoromethylquinoxaline 1,4-dioxide.

  Bioorganic & medicinal chemistry 20100501

• Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei Benth.

  Acta crystallographica. Section D, Biological crystallography 20100501

• Purification and characterisation of rat kidney glutathione reductase.

  The protein journal 20100501

• In vitro and in vivo metabolism of the radiolytic compound 2-dodecylcyclobutanone.

  Journal of food science 20100501

• Deviant nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated Ca2+ signaling upon lysosome proliferation.

  The Journal of biological chemistry 20100430

• Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking.

  Current biology : CB 20100427

• Crystal structure and comparative functional analyses of a Mycobacterium aldo-keto reductase.

  Journal of molecular biology 20100423

• Cysteine as a modulator residue in the active site of xenobiotic reductase A: a structural, thermodynamic and kinetic study.

  Journal of molecular biology 20100423

• Insights into the specificity of thioredoxin reductase-thioredoxin interactions. A structural and functional investigation of the yeast thioredoxin system.

  Biochemistry 20100420

• Challenges of steroid biotransformation with human cytochrome P450 monooxygenase CYP21 using resting cells of recombinant Schizosaccharomyces pombe.

  Journal of biotechnology 20100415

• Elevated cytosolic Na+ increases mitochondrial formation of reactive oxygen species in failing cardiac myocytes.

  Circulation 20100413

• Transient hyperoxic reoxygenation reduces cytochrome C oxidase activity by increasing superoxide dismutase and nitric oxide.

  The Journal of biological chemistry 20100409

• Crystal structure and catalytic mechanism of leucoanthocyanidin reductase from Vitis vinifera.

  Journal of molecular biology 20100409

• Alpha-ketoisocaproic acid and leucine provoke mitochondrial bioenergetic dysfunction in rat brain.

  Brain research 20100409

• Mechanistic insights into ferredoxin-NADP(H) reductase catalysis involving the conserved glutamate in the active site.

  Journal of molecular biology 20100402

• Cytosolic NADP(+)-dependent isocitrate dehydrogenase regulates cadmium-induced apoptosis.

  Biochemical pharmacology 20100401

• Purification and characterization of an anti-Prelog alcohol dehydrogenase from Oenococcus oeni that reduces 2-octanone to (R)-2-octanol.

  Biotechnology letters 20100401

• The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma.

  Acta neuropathologica 20100401

• Effect of purified saponin mixture from Astragalus corniculatus on enzyme- and non-enzyme-induced lipid peroxidation in liver microsomes from spontaneously hypertensive rats and normotensive rats.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20100401

• Involvement of mitochondria in the control of plant cell NAD(P)H reduction levels.

  Biochemical Society transactions 20100401

• Oxidative stress and hypertension: current concepts.

  Current hypertension reports 20100401

• [Effect of post-treatment with dry extract from vicia truncatula on NADPH-GSH dependent system of rat liver during chronic alcohol intoxication].

  Eksperimental'naia i klinicheskaia farmakologiia 20100401

• Constitutive NADPH-dependent electron transferase activity of the Nox4 dehydrogenase domain.

  Biochemistry 20100323

• Oxidation of N-Nitrosoalkylamines by human cytochrome P450 2A6: sequential oxidation to aldehydes and carboxylic acids and analysis of reaction steps.

  The Journal of biological chemistry 20100312

• Mechanism of the hydride transfer between Anabaena Tyr303Ser FNR(rd)/FNR(ox) and NADP+/H. A combined pre-steady-state kinetic/ensemble-averaged transition-state theory with multidimensional tunneling study.

  The journal of physical chemistry. B 20100311

• Nuclear magnetic resonance study of the role of M42 in the solution dynamics of Escherichia coli dihydrofolate reductase.

  Biochemistry 20100302

• Improving NADPH availability for natural product biosynthesis in Escherichia coli by metabolic engineering.

  Metabolic engineering 20100301

• Transhydrogenase and the anaerobic mitochondrial metabolism of adult Hymenolepis diminuta.

  Parasitology 20100301

• Dynamic flux responses in riboflavin overproducing Bacillus subtilis to increasing glucose limitation in fed-batch culture.

  Biotechnology and bioengineering 20100301

• Phylogenetically-based variation in the regulation of the Calvin cycle enzymes, phosphoribulokinase and glyceraldehyde-3-phosphate dehydrogenase, in algae.

  Journal of experimental botany 20100301

• AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease.

  American journal of physiology. Cell physiology 20100301

• De novo fatty acid synthesis and NADPH generation in equine adipose and liver tissue.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20100301

• The effect of tert-butylhydroquinone-induced oxidative stress in MDBK cells using XTT assay: implication of tert-butylhydroquinone-induced NADPH generating enzymes.

  The Journal of veterinary medical science 20100301

• How does a valine residue that modulates heme-NO binding kinetics in inducible NO synthase regulate enzyme catalysis?

  Journal of inorganic biochemistry 20100301

• Calcium signaling via two-pore channels: local or global, that is the question.

  American journal of physiology. Cell physiology 20100301

• Electron transfer in the complex of membrane-bound human cytochrome P450 3A4 with the flavin domain of P450BM-3: the effect of oligomerization of the heme protein and intermittent modulation of the spin equilibrium.

  Biochimica et biophysica acta 20100301

• Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries.

  American journal of physiology. Heart and circulatory physiology 20100301

• Mitochondria isolated in nearly isotonic KCl buffer: focus on cardiolipin and organelle morphology.

  Biochimica et biophysica acta 20100301

• The glucocorticoid-activating enzyme 11beta-hydroxysteroid dehydrogenase type 1 has broad substrate specificity: Physiological and toxicological considerations.

  The Journal of steroid biochemistry and molecular biology 20100301

• Discovery of potent and selective bicyclic A(2B) adenosine receptor antagonists via bioisosteric amide replacement.

  Bioorganic & medicinal chemistry letters 20100301

• Inhibition of lipid peroxidation of herbal extracts (obtained from plant drug mixtures of Myrtilli folium, Phaseoli fructus sine seminibus and Salviae folium) used in type 2 diabetes mellitus.

  Acta biologica Hungarica 20100301

• Transcription profiling of acute temperature stress in the Antarctic plunderfish Harpagifer antarcticus.

  Marine genomics 20100301

• Upregulation of cytosolic NADP+-dependent isocitrate dehydrogenase by hyperglycemia protects renal cells against oxidative stress.

  Molecules and cells 20100227

• The thioredoxin-thioredoxin reductase system can function in vivo as an alternative system to reduce oxidized glutathione in Saccharomyces cerevisiae.

  The Journal of biological chemistry 20100226

• Subdivision of the bacterioferritin comigratory protein family of bacterial peroxiredoxins based on catalytic activity.

  Biochemistry 20100216

• Evaluation of inhibition of fatty acid synthase by ursolic acid: positive cooperation mechanism.

  Biochemical and biophysical research communications 20100212

• Expression and purification of his-tagged recombinant mouse zeta-crystallin.

  Protein expression and purification 20100201

• Structural insights into Staphylococcus aureus enoyl-ACP reductase (FabI), in complex with NADP and triclosan.

  Proteins 20100201

• Glucose-6-phosphate dehydrogenase-deficient mice have increased renal oxidative stress and increased albuminuria.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100201

• Purification and characterization of vanillin dehydrogenases from alkaliphile Micrococcus sp. TA1 and neutrophile Burkholderia cepacia TM1.

  FEMS microbiology letters 20100201

• Oscillatory growth in lily pollen tubes does not require aerobic energy metabolism.

  Plant physiology 20100201

• Transcriptional regulation of cytokines and oxidative stress by gallic acid in human THP-1 monocytes.

  Cytokine 20100201

• 7alpha-hydroxytestosterone affects 1 beta-hydroxysteroid dehydrogenase 1 direction in rat Leydig cells.

  Endocrinology 20100201

• Use of NAD(P)H and flavoprotein autofluorescence transients to probe neuron and astrocyte responses to synaptic activation.

  Neurochemistry international 20100201

• Sympathoinhibition induced by centrally administered atorvastatin is associated with alteration of NAD(P)H and Mn superoxide dismutase activity in rostral ventrolateral medulla of stroke-prone spontaneously hypertensive rats.

  Journal of cardiovascular pharmacology 20100201

• Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.

  Acta crystallographica. Section D, Biological crystallography 20100201

• Interplay between the NADP-linked thioredoxin and glutathione systems in Arabidopsis auxin signaling.

  The Plant cell 20100201

• Probing the roles of conserved arginine-44 of Escherichia coli dihydrofolate reductase in its function and stability by systematic sequence perturbation analysis.

  Biochemical and biophysical research communications 20100122

• Development and validation of a cytochrome c-coupled assay for pteridine reductase 1 and dihydrofolate reductase.

  Analytical biochemistry 20100115

• pO(2)-dependent NO production determines OPPC activity in macrophages.

  Free radical biology & medicine 20100115

• Iron oxide/carbon black (Fe2O3/CB) composite electrode for the detection of reduced nicotinamide cofactors using an amperometric method under a low overpotential.

  Biosensors & bioelectronics 20100115

• Retrorsine, but not monocrotaline, is a mechanism-based inactivator of P450 3A4.

  Chemico-biological interactions 20100105

• Protein-protein interactions at an enzyme-substrate interface: characterization of transient reaction intermediates throughout a full catalytic cycle of Escherichia coli thioredoxin reductase.

  Proteins 20100101

• Sequence analysis and heterologous expression of a new cytochrome P450 monooxygenase from Rhodococcus sp. for asymmetric sulfoxidation.

  Applied microbiology and biotechnology 20100101

• Purification and characterization of a glutathione reductase from Phaeodactylum tricornutum.

  Protist 20100101

• Energetic performance is improved by specific activation of K+ fluxes through K(Ca) channels in heart mitochondria.

  Biochimica et biophysica acta 20100101

• Glutathione S-transferase catalyzed desulfonylation of a sulfonylfuropyridine.

  Drug metabolism and disposition: the biological fate of chemicals 20100101

• Hexose-6-phosphate dehydrogenase in the endoplasmic reticulum.

  Biological chemistry 20100101

• Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite.

  Drug metabolism and disposition: the biological fate of chemicals 20100101

• Identification of multiple glutathione conjugates of 8-amino- 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline maleate (nomifensine) in liver microsomes and hepatocyte preparations: evidence of the bioactivation of nomifensine.

  Drug metabolism and disposition: the biological fate of chemicals 20100101

• Altered redox state of luminal pyridine nucleotides facilitates the sensitivity towards oxidative injury and leads to endoplasmic reticulum stress dependent autophagy in HepG2 cells.

  The international journal of biochemistry & cell biology 20100101

• CD38-mediated Ca2+ signaling contributes to angiotensin II-induced activation of hepatic stellate cells: attenuation of hepatic fibrosis by CD38 ablation.

  The Journal of biological chemistry 20100101

• Pyridine salvage and nicotinic acid conjugate synthesis in leaves of mangrove species.

  Phytochemistry 20100101

• Subcellular and tissue localization of NAD kinases from Arabidopsis: compartmentalization of de novo NADP biosynthesis.

  Planta 20100101

• High-fructose diet elevates myocardial superoxide generation in mice in the absence of cardiac hypertrophy.

  Nutrition (Burbank, Los Angeles County, Calif.) 20100101

• Importance of NADPH supply for improved L-valine formation in Corynebacterium glutamicum.

  Biotechnology progress 20100101

• Selective probing of a NADPH site controlled light-induced enzymatic catalysis.

  Journal of molecular recognition : JMR 20100101

• Ferulic acid protects human umbilical vein endothelial cells from radiation induced oxidative stress by phosphatidylinositol 3-kinase and extracellular signal-regulated kinase pathways.

  Biological & pharmaceutical bulletin 20100101

• Molecular modeling of the reductase domain to elucidate the reaction mechanism of reduction of peptidyl thioester into its corresponding alcohol in non-ribosomal peptide synthetases.

  BMC structural biology 20100101

• Oxidant-redox regulation of pulmonary vascular responses to hypoxia and nitric oxide-cGMP signaling.

  Cardiology in review 20100101

• The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions.

  PloS one 20100101

• The phosphate makes a difference: cellular functions of NADP.

  Redox report : communications in free radical research 20100101

• Assessment of the inactivation potential of desethylamiodarone on human CYP1A1.

  Drug metabolism letters 20100101

• The role of intracellular ion channels in regulating cytoplasmic calciumin pulmonary arterial mmooth muscle: which store and where?

  Advances in experimental medicine and biology 20100101

• Membrane potential-related effect of calcium on reactive oxygen species generation in isolated brain mitochondria.

  Biochimica et biophysica acta 20100101

• Identification and molecular characterization of a novel flavin-free NADPH preferred azoreductase encoded by azoB in Pigmentiphaga kullae K24.

  BMC biochemistry 20100101

• Measuring protein kinase and sugar kinase activity in plant pathogenic fusarium species.

  Methods in molecular biology (Clifton, N.J.) 20100101

• Diminished NADPH transhydrogenase activity and mitochondrial redox regulation in human failing myocardium.

  Biochimica et biophysica acta 20100101

• Inhibitory and stimulative effects of amiodarone on metabolism of carvedilol in human liver microsomes.

  Biological & pharmaceutical bulletin 20100101

• Two-photon microscopy for non-invasive, quantitative monitoring of stem cell differentiation.

  PloS one 20100101

• Dynamics and control of the central carbon metabolism in hepatoma cells.

  BMC systems biology 20100101

• Chlorella vulgaris aldehyde reductase is capable of functioning as ferric reductase and of driving the fenton reaction in the presence of free flavin.

  Bioscience, biotechnology, and biochemistry 20100101

• Glutamate dehydrogenase and glutamine synthetase are regulated in response to nitrogen availability in Myocbacterium smegmatis.

  BMC microbiology 20100101

• Protection against LPS-induced cartilage inflammation and degradation provided by a biological extract of Mentha spicata.

  BMC complementary and alternative medicine 20100101

• Schisandrin B-induced glutathione antioxidant response and cardioprotection are mediated by reactive oxidant species production in rat hearts.

  Biological & pharmaceutical bulletin 20100101

• Selective inhibition of the tumor marker AKR1B10 by antiinflammatory N-phenylanthranilic acids and glycyrrhetic acid.

  Biological & pharmaceutical bulletin 20100101

• Heterologous expression and maturation of an NADP-dependent [NiFe]-hydrogenase: a key enzyme in biofuel production.

  PloS one 20100101

• Engineering cofactor preference of ketone reducing biocatalysts: A mutagenesis study on a γ-diketone reductase from the yeast Saccharomyces cerevisiae serving as an example.

  International journal of molecular sciences 20100101

• Contribution of hexose-6-phosphate dehydrogenase to NADPH content and redox environment in the endoplasmic reticulum.

  Redox report : communications in free radical research 20100101

• Insights in 17beta-HSD1 enzyme kinetics and ligand binding by dynamic motion investigation.

  PloS one 20100101

• A systematic investigation of Escherichia coli central carbon metabolism in response to superoxide stress.

  BMC systems biology 20100101

• NOX/NADPH oxidase, the superoxide-generating enzyme: its transcriptional regulation and physiological roles.

  Journal of pharmacological sciences 20100101

• [Markers of chloric acid (I) in biological systems--identification and properties].

  Postepy biochemii 20100101

• Flavonoids diosmetin and hesperetin are potent inhibitors of cytochrome P450 2C9-mediated drug metabolism in vitro.

  Drug metabolism and pharmacokinetics 20100101

• Relating mutant genotype to phenotype via quantitative behavior of the NADPH redox cycle in human erythrocytes.

  PloS one 20100101

• Chromate reduction by cell-free extract of Bacillus firmus KUCr1.

  Polish journal of microbiology 20100101

• Rat aldose reductase-like protein (AKR1B14) efficiently reduces the lipid peroxidation product 4-oxo-2-nonenal.

  Biological & pharmaceutical bulletin 20100101

• Modeling and simulation of the main metabolism in Escherichia coli and its several single-gene knockout mutants with experimental verification.

  Microbial cell factories 20100101

• Activation of the AMP-activated protein kinase enhances glucose-stimulated insulin secretion in mouse β-cells.

  Islets 20100101

• Antioxidant and antifungal properties of benzimidazole derivatives.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20100101

• Oxidative damage and redox change in pea seeds treated with cadmium.

  Comptes rendus biologies 20100101

• Conversion of quinate to 3-dehydroshikimate by Ca-alginate-immobilized membrane of Gluconobacter oxydans IFO 3244 and subsequent asymmetric reduction of 3-dehydroshikimate to shikimate by immobilized cytoplasmic NADP-shikimate dehydrogenase.

  Bioscience, biotechnology, and biochemistry 20100101

• Nitric oxide in paraquat-mediated toxicity: A review.

  Journal of biochemical and molecular toxicology 20100101

• Modeling single nucleotide polymorphisms in the human AKR1C1 and AKR1C2 genes: implications for functional and genotyping analyses.

  PloS one 20100101

• [Effect of plague 'murine' toxin on activity of antioxidant system in cells of experimental animals].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20100101

• Overexpression, isolation, and spectroscopic characterization of the bidirectional [NiFe] hydrogenase from Synechocystis sp. PCC 6803.

  The Journal of biological chemistry 20091225

• Domain motion in cytochrome P450 reductase: conformational equilibria revealed by NMR and small-angle x-ray scattering.

  The Journal of biological chemistry 20091225

• Two conformations are better than one: domain motion in cytochrome P450 reductase. conformational equilibria revealed by nmr and small-angle X-ray scattering.

  The Journal of biological chemistry 20091225

• Crystal structures of Pseudomonas syringae pv. tomato DC3000 quinone oxidoreductase and its complex with NADPH.

  Biochemical and biophysical research communications 20091218

• Electrochemical probing of in vivo 5-hydroxymethyl furfural reduction in Saccharomyces cerevisiae.

  Analytical chemistry 20091215

• Deazaflavins as mediators in light-driven cytochrome P450 catalyzed hydroxylations.

  Chemical communications (Cambridge, England) 20091214

• Analogues of the nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist Ned-19 indicate two binding sites on the NAADP receptor.

  The Journal of biological chemistry 20091211

• Kinetic characterization of xenobiotic reductase A from Pseudomonas putida 86.

  Biochemistry 20091208

• Elevated peroxidative glutathione redox status in atherosclerotic patients with increased thickness of carotid intima media.

  Chinese medical journal 20091205

• Influence of naturally-occurring 5'-pyrophosphate-linked substituents on the binding of adenylic inhibitors to ribonuclease a: an X-ray crystallographic study.

  Biopolymers 20091201

• Naphthoquinones and bioactive compounds from tobacco as modulators of neuronal nitric oxide synthase activity.

  Phytotherapy research : PTR 20091201

• Heterologous expression and molecular characterization of the NAD(P)H:acceptor oxidoreductase (FerB) of Paracoccus denitrificans.

  Protein expression and purification 20091201

• Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins.

  Drug metabolism and disposition: the biological fate of chemicals 20091201

• Rosuvastatin attenuates Ang II--mediated cardiomyocyte hypertrophy via inhibition of LOX-1.

  Journal of cardiovascular pharmacology and therapeutics 20091201

• Accumulation of advanced oxidation protein products induces podocyte apoptosis and deletion through NADPH-dependent mechanisms.

  Kidney international 20091201

• CYP7B1-mediated metabolism of 5alpha-androstane-3alpha,17beta-diol (3alpha-Adiol): a novel pathway for potential regulation of the cellular levels of androgens and neurosteroids.

  Biochimica et biophysica acta 20091201

• Resveratrol supplementation gender independently improves endothelial reactivity and suppresses superoxide production in healthy rats.

  Cardiovascular drugs and therapy 20091201

• Mitochondrial bioenergetics linked to the manifestation of programmed cell death during somatic embryogenesis of Abies alba.

  Planta 20091201

• Clinical, genetic, and enzymatic characterization of P450 oxidoreductase deficiency in four patients.

  The Journal of clinical endocrinology and metabolism 20091201

• Structure of glyceraldehyde-3-phosphate dehydrogenase from the archaeal hyperthermophile Methanocaldococcus jannaschii.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20091201

• Effect of a herbal medicine on fatty liver in rats fed ethanol chronically.

  Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence 20091201

• Xylose reductase from the thermophilic fungus Talaromyces emersonii: cloning and heterologous expression of the native gene (Texr) and a double mutant (TexrK271R + N273D) with altered coenzyme specificity.

  Journal of biosciences 20091201

• [Assessment of mitochondrial metabolic oxidative state in living cardiomyocytes with spectrally-resolved fluorescence lifetime spectroscopy of NAD(P)H].

  Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20091201

• Meta- and pooled analyses of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and colorectal cancer: a HuGE-GSEC review.

  American journal of epidemiology 20091115

• Ferredoxin:NADP+ oxidoreductase association with phycocyanin modulates its properties.

  The Journal of biological chemistry 20091113

• Ocean science. Photosynthesis in the open ocean.

  Science (New York, N.Y.) 20091113

• Evidence that the major metabolites accumulating in medium-chain acyl-CoA dehydrogenase deficiency disturb mitochondrial energy homeostasis in rat brain.

  Brain research 20091103

• Ionic liquids as performance additives for electroenzymatic syntheses.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20091102

• Mitochondrial calcium as a key regulator of mitochondrial ATP production in mammalian cells.

  Biochimica et biophysica acta 20091101

• Involvement of oxidative pathways in cytokine-induced secretory phospholipase A2-IIA in astrocytes.

  Neurochemistry international 20091101

• Modular coenzyme specificity: a domain-swopped chimera of glutamate dehydrogenase.

  Proteins 20091101

• A continuous microplate assay for sirtuins and nicotinamide-producing enzymes.

  Analytical biochemistry 20091101

• Effects of hypoxia on testosterone release in rat Leydig cells.

  American journal of physiology. Endocrinology and metabolism 20091101

• Functional characterization of human cytochrome P450 2S1 using a synthetic gene-expressed protein in Escherichia coli.

  Molecular pharmacology 20091101

• A systems-level analysis of the effects of light quality on the metabolism of a cyanobacterium.

  Plant physiology 20091101

• Characterization of two genes involved in chromate resistance in a Cr(VI)-hyper-resistant bacterium.

  Extremophiles : life under extreme conditions 20091101

• Binding-equilibrium and kinetic studies of anthocyanidin reductase from Vitis vinifera.

  Archives of biochemistry and biophysics 20091101

• Metabolic-dependent changes in plant cell redox power after ozone exposure.

  Plant biology (Stuttgart, Germany) 20091101

• Metabolite screening of aromatic amine hair dyes using in vitro hepatic models.

  Xenobiotica; the fate of foreign compounds in biological systems 20091101

• Determination of reduced nicotinamide adenine dinucleotide phosphate concentration using high-performance liquid chromatography with fluorescence detection: ratio of the reduced form as a biomarker of oxidative stress.

  Biological & pharmaceutical bulletin 20091101

• Multiple redox and non-redox interactions define 2-Cys peroxiredoxin as a regulatory hub in the chloroplast.

  Molecular plant 20091101

• The Saccharomyces cerevisiae YMR315W gene encodes an NADP(H)-specific oxidoreductase regulated by the transcription factor Stb5p in response to NADPH limitation.

  New biotechnology 20091031

• Structural basis for substrate recognition in the enzymatic component of ADP-ribosyltransferase toxin CDTa from Clostridium difficile.

  The Journal of biological chemistry 20091016

• PCB-induced endothelial cell dysfunction: role of poly(ADP-ribose) polymerase.

  Biochemical pharmacology 20091015

• Plasmodium falciparum ferredoxin-NADP+ reductase His286 plays a dual role in NADP(H) binding and catalysis.

  Biochemistry 20091013

• The cytosolic subunit p67phox of the NADPH-oxidase complex does not bind NADPH.

  FEBS letters 20091006

• Inhibition of drug metabolizing cytochrome P450s by the aromatase inhibitor drug letrozole and its major oxidative metabolite 4,4'-methanol-bisbenzonitrile in vitro.

  Cancer chemotherapy and pharmacology 20091001

• Enhanced docosahexaenoic acid production by reinforcing acetyl-CoA and NADPH supply in Schizochytrium sp. HX-308.

  Bioprocess and biosystems engineering 20091001

• Metabolomics for biotransformations: Intracellular redox cofactor analysis and enzyme kinetics offer insight into whole cell processes.

  Biotechnology and bioengineering 20091001

• Effects of chronic 4-n-nonylphenol treatment on aortic vasoconstriction and vasorelaxation in rats.

  Archives of toxicology 20091001

• Identification of radicals formed in the reaction mixture of bovine kidney microsomes with NADPH.

  Journal of biochemistry 20091001

• Metabolism-related liabilities of a potent histone deacetylase (HDAC) inhibitor and relevance of the route of administration on its metabolic fate.

  Xenobiotica; the fate of foreign compounds in biological systems 20091001

• A novel NADPH-dependent aldehyde reductase gene from Saccharomyces cerevisiae NRRL Y-12632 involved in the detoxification of aldehyde inhibitors derived from lignocellulosic biomass conversion.

  Gene 20091001

• Decreased transketolase activity contributes to impaired hippocampal neurogenesis induced by thiamine deficiency.

  Journal of neurochemistry 20091001

• Computational design of Candida boidinii xylose reductase for altered cofactor specificity.

  Protein science : a publication of the Protein Society 20091001

• Mitochondrial metabolism and cancer.

  Annals of the New York Academy of Sciences 20091001

• Studies on biological reduction of chromate by Streptomyces griseus.

  Journal of hazardous materials 20090930

• Inhibition of methionine sulfoxide reduction by dimethyl sulfoxide.

  BMB reports 20090930

• Removal of substrate inhibition and increase in maximal velocity in the short chain dehydrogenase/reductase salutaridine reductase involved in morphine biosynthesis.

  The Journal of biological chemistry 20090925

• Characterization of two novel aldo-keto reductases from Arabidopsis: expression patterns, broad substrate specificity, and an open active-site structure suggest a role in toxicant metabolism following stress.

  Journal of molecular biology 20090918

• Mechanism of flavin reduction and oxidation in the redox-sensing quinone reductase Lot6p from Saccharomyces cerevisiae.

  Biochemistry 20090915

• Activation of translation via reduction by thioredoxin-thioredoxin reductase in Saccharomyces cerevisiae.

  FEBS letters 20090903

• Comparison of engineered Saccharomyces cerevisiae and engineered Escherichia coli for the production of an optically pure keto alcohol.

  Applied microbiology and biotechnology 20090901

• The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca(2+) release channels.

  Pflugers Archiv : European journal of physiology 20090901

• Chlamydophila pneumoniae triggers release of CCL20 and vascular endothelial growth factor from human bronchial epithelial cells through enhanced intracellular oxidative stress and MAPK activation.

  Journal of clinical immunology 20090901

• Bioassays for bomb-makers: proof of concept.

  Analytical and bioanalytical chemistry 20090901

• Carbon fluxes of xylose-consuming Saccharomyces cerevisiae strains are affected differently by NADH and NADPH usage in HMF reduction.

  Applied microbiology and biotechnology 20090901

• An in vitro evaluation of the victim and perpetrator potential of the anticancer agent laromustine (VNP40101M), based on reaction phenotyping and inhibition and induction of cytochrome P450 enzymes.

  Drug metabolism and disposition: the biological fate of chemicals 20090901

• In vitro inhibition of multiple cytochrome P450 isoforms by xanthone derivatives from mangosteen extract.

  Drug metabolism and disposition: the biological fate of chemicals 20090901

• Contrasting influence of NADPH and a NADPH-regenerating system on the metabolism of carbonyl-containing compounds in hepatic microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20090901

• Species differences for stereoselective metabolism of ethofumesate and its enantiomers in vitro.

  Xenobiotica; the fate of foreign compounds in biological systems 20090901

• Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17beta-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 cells.

  Endocrinology 20090901

• The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores.

  Pflugers Archiv : European journal of physiology 20090901

• Pleiotropic modulation of carbon and nitrogen metabolism in Arabidopsis plants overexpressing the NAD kinase2 gene.

  Plant physiology 20090901

• Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells.

  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20090901

• Bipartite recognition and conformational sampling mechanisms for hydride transfer from nicotinamide coenzyme to FMN in pentaerythritol tetranitrate reductase.

  The FEBS journal 20090901

• Profiling patterns of glutathione reductase inhibition by the natural product illudin S and its acylfulvene analogues.

  Molecular bioSystems 20090901

• Recruitment of NAADP-sensitive acidic Ca2+ stores by glutamate.

  The Biochemical journal 20090827

• Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics.

  The Journal of biological chemistry 20090821

• Metabolic flux analysis of a phenol producing mutant of Pseudomonas putida S12: verification and complementation of hypotheses derived from transcriptomics.

  Journal of biotechnology 20090820

• Structural comparison of chromosomal and exogenous dihydrofolate reductase from Staphylococcus aureus in complex with the potent inhibitor trimethoprim.

  Proteins 20090815

• Analysis of free and bound NADPH in aqueous extract of human placenta used as wound healer.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090815

• Determination of low level nitrite and nitrate in biological, food and environmental samples by gas chromatography-mass spectrometry and liquid chromatography with fluorescence detection.

  Talanta 20090815

• Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells.

  Archives of biochemistry and biophysics 20090815

• Boric acid inhibits stored Ca2+ release in DU-145 prostate cancer cells.

  Cell biology and toxicology 20090801

• Caloric restriction counteracts age-related changes in the activities of sorbitol metabolizing enzymes from mouse liver.

  Biogerontology 20090801

• Endothelin-1 contributes to hemoglobin glutamer-200-mediated hepatocellular dysfunction after hemorrhagic shock.

  Shock (Augusta, Ga.) 20090801

• Formation of all-trans retinol after visual pigment bleaching in mouse photoreceptors.

  Investigative ophthalmology & visual science 20090801

• Probing the molecular determinants of coenzyme selectivity in the P450 BM3 FAD/NADPH domain.

  Biochimica et biophysica acta 20090801

• Verdoheme formation in Proteus mirabilis catalase.

  Biochimica et biophysica acta 20090801

• Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.

  Drug metabolism and disposition: the biological fate of chemicals 20090801

• NAADP receptors mediate calcium signaling stimulated by endothelin-1 and norepinephrine in renal afferent arterioles.

  American journal of physiology. Renal physiology 20090801

• Clinical mutants of human glucose 6-phosphate dehydrogenase: impairment of NADP(+) binding affects both folding and stability.

  Biochimica et biophysica acta 20090801

• The involvement of aldosterone in cyclic stretch-mediated activation of NADPH oxidase in vascular smooth muscle cells.

  Hypertension research : official journal of the Japanese Society of Hypertension 20090801

• mu-opioid receptor-stimulated synthesis of reactive oxygen species is mediated via phospholipase D2.

  Journal of neurochemistry 20090801

• Inhibition of succinate-linked respiration and complex II activity by hydrogen peroxide.

  Archives of biochemistry and biophysics 20090801

• Cytochrome P450-dependent metabolism of PCB52 in the nematode Caenorhabditis elegans.

  Archives of biochemistry and biophysics 20090801

• Structural and mechanistic aspects of flavoproteins: photosynthetic electron transfer from photosystem I to NADP+.

  The FEBS journal 20090801

• The effect of pH on the initial rate kinetics of the dimeric biliverdin-IXalpha reductase from the cyanobacterium Synechocystis PCC6803.

  The FEBS journal 20090801

• Inhibitory properties and X-ray crystallographic study of the binding of AR-101, AR-102 and iclaprim in ternary complexes with NADPH and dihydrofolate reductase from Staphylococcus aureus.

  Acta crystallographica. Section D, Biological crystallography 20090801

• Insights into the alkyl peroxide reduction pathway of Xanthomonas campestris bacterioferritin comigratory protein from the trapped intermediate-ligand complex structures.

  Journal of molecular biology 20090731

• Absence of nitric-oxide synthase in sequentially purified rat liver mitochondria.

  The Journal of biological chemistry 20090724

• Inhibition of human steroid 5beta-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complex.

  The Journal of biological chemistry 20090724

• Characterisation of a recombinant NADP-dependent glycerol dehydrogenase from Gluconobacter oxydans and its application in the production of L-glyceraldehyde.

  Chembiochem : a European journal of chemical biology 20090720

• Neutralizing a surface charge on the FMN subdomain increases the activity of neuronal nitric-oxide synthase by enhancing the oxygen reactivity of the enzyme heme-nitric oxide complex.

  The Journal of biological chemistry 20090717

• Integrative normalization and comparative analysis for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.

  Analytical chemistry 20090715

• Second messenger signaling: multiple receptors for NAADP.

  Current biology : CB 20090714

• Protective role of estrogen receptor-alpha on lower chlorinated PCB congener-induced DNA damage and repair in human tumoral breast cells.

  Toxicology letters 20090710

• Cryogenic and laser photoexcitation studies identify multiple roles for active site residues in the light-driven enzyme protochlorophyllide oxidoreductase.

  The Journal of biological chemistry 20090703

• Soluble and particulate Co-Cr-Mo alloy implant metals activate the inflammasome danger signaling pathway in human macrophages: a novel mechanism for implant debris reactivity.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20090701

• Synthesis and evaluation of pyrido[1,2-a]pyrimidines as inhibitors of nitric oxide synthases.

  European journal of medicinal chemistry 20090701

• The regulation of xanthophyll cycle activity and of non-photochemical fluorescence quenching by two alternative electron flows in the diatoms Phaeodactylum tricornutum and Cyclotella meneghiniana.

  Biochimica et biophysica acta 20090701

• Dehydromonocrotaline induces cyclosporine A-insensitive mitochondrial permeability transition/cytochrome c release.

  Toxicon : official journal of the International Society on Toxinology 20090701

• Comparative mutagenic effects of structurally similar flavonoids quercetin and taxifolin on tester strains Salmonella typhimurium TA102 and Escherichia coli WP-2 uvrA.

  Environmental and molecular mutagenesis 20090701

• Reversal of coenzyme specificity and improvement of catalytic efficiency of Pichia stipitis xylose reductase by rational site-directed mutagenesis.

  Biotechnology letters 20090701

• Overexpression of NAD kinase in recombinant Escherichia coli harboring the phbCAB operon improves poly(3-hydroxybutyrate) production.

  Applied microbiology and biotechnology 20090701

• Oxidative stress-induced changes in pyridine nucleotides and chemoattractant 5-lipoxygenase products in aging neutrophils.

  Free radical biology & medicine 20090701

• Crystal structures of cyclohexanone monooxygenase reveal complex domain movements and a sliding cofactor.

  Journal of the American Chemical Society 20090701

• Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH.

  American journal of physiology. Heart and circulatory physiology 20090701

• Chymase plays an important role in left ventricular remodeling induced by intermittent hypoxia in mice.

  Hypertension (Dallas, Tex. : 1979) 20090701

• Characterization of a soluble oxidoreductase from the thermophilic bacterium Carboxydothermus ferrireducens.

  Extremophiles : life under extreme conditions 20090701

• Purification and characterization of a (R)-1-phenyl-1,3-propanediol-producing enzyme from Trichosporon fermentans AJ-5152 and enzymatic (R)-1-phenyl-1,3-propanediol production.

  Bioscience, biotechnology, and biochemistry 20090701

• Chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae.

  Biochemistry 20090630

• Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3.

  The Journal of biological chemistry 20090619

• Peroxiredoxin 2 and peroxidase enzymatic activity of mammalian spermatozoa.

  Biology of reproduction 20090601

• Acute atrial tachyarrhythmia induces angiotensin II type 1 receptor-mediated oxidative stress and microvascular flow abnormalities in the ventricles.

  European heart journal 20090601

• As in humans, pregnancy increases the clearance of the protease inhibitor nelfinavir in the nonhuman primate Macaca nemestrina.

  The Journal of pharmacology and experimental therapeutics 20090601

• Quantifying interactions within the NADP(H) enzyme network in Drosophila melanogaster.

  Genetics 20090601

• Ca2+-dependent permeability transition regulation in rat brain mitochondria by 2',3'-cyclic nucleotides and 2',3'-cyclic nucleotide 3'-phosphodiesterase.

  American journal of physiology. Cell physiology 20090601

• Two novel metal-independent long-chain alkyl alcohol dehydrogenases from Geobacillus thermodenitrificans NG80-2.

  Microbiology (Reading, England) 20090601

• Determination of phosphorylation sites for NADP-specific isocitrate dehydrogenase from mycobacterium tuberculosis.

  Journal of biomolecular structure & dynamics 20090601

• Purification, crystallization and preliminary X-ray analysis of L-sorbose reductase from Gluconobacter frateurii complexed with L-sorbose or NADPH.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20090601

• Imaging reactive oxygen species dynamics in living cells and tissues.

  Frontiers in bioscience (Scholar edition) 20090601

• Cloning, expression, and characterization of xylose reductase with higher activity from Candida tropicalis.

  Journal of microbiology (Seoul, Korea) 20090601

• The multifunctional enzyme CYP71B15 (PHYTOALEXIN DEFICIENT3) converts cysteine-indole-3-acetonitrile to camalexin in the indole-3-acetonitrile metabolic network of Arabidopsis thaliana.

  The Plant cell 20090601

• Effect of moderate hypoxia/reoxygenation on mitochondrial adaptation to acute severe hypoxia.

  Acta biologica Hungarica 20090601

• Consideration of diurnal variations in human blood NAD and NADP concentrations.

  Journal of nutritional science and vitaminology 20090601

• Effect of transient and permanent permeability transition pore opening on NAD(P)H localization in intact cells.

  The Journal of biological chemistry 20090529

• Conformational changes in a plant ketol-acid reductoisomerase upon Mg(2+) and NADPH binding as revealed by two crystal structures.

  Journal of molecular biology 20090529

• NAADP mobilizes calcium from acidic organelles through two-pore channels.

  Nature 20090528

• Kinetic mechanism of ornithine hydroxylase (PvdA) from Pseudomonas aeruginosa: substrate triggering of O2 addition but not flavin reduction.

  Biochemistry 20090526

• The solution structure of Bacillus anthracis dihydrofolate reductase yields insight into the analysis of structure-activity relationships for novel inhibitors.

  Biochemistry 20090519

• Control of superoxide and nitric oxide formation during human sperm capacitation.

  Free radical biology & medicine 20090515

• Dual roles of Lys(57) at the dimer interface of human mitochondrial NAD(P)+-dependent malic enzyme.

  The Biochemical journal 20090513

• Cisplatin impairs rat liver mitochondrial functions by inducing changes on membrane ion permeability: prevention by thiol group protecting agents.

  Toxicology 20090502

• Adzuki bean: a new resource of biocatalyst for asymmetric reduction of aromatic ketones with high stereoselectivity and substrate tolerance.

  Bioresource technology 20090501

• A predominate role of CYP1A2 for the metabolism of nabumetone to the active metabolite, 6-methoxy-2-naphthylacetic acid, in human liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20090501

• Mycothiol disulfide reductase: a continuous assay for slow time-dependent inhibitors.

  Analytical biochemistry 20090501

• Effects of glutathione reductase inhibition on cellular thiol redox state and related systems.

  Archives of biochemistry and biophysics 20090501

• Cloning and characterization of a squalene synthase gene from a petroleum plant, Euphorbia tirucalli L.

  Planta 20090501

• X-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor design.

  Journal of structural biology 20090501

• An enzymatic fluorimetric assay for glucose-6-phosphate: application in an in vitro Warburg-like effect.

  Analytical biochemistry 20090501

• Oxidase activity of a flavin-dependent thymidylate synthase.

  The FEBS journal 20090501

• From proteomics to structural studies of cytosolic/mitochondrial-type thioredoxin systems in barley seeds.

  Molecular plant 20090501

• Pyridine nucleotide cycling and control of intracellular redox state in relation to poly (ADP-ribose) polymerase activity and nuclear localization of glutathione during exponential growth of Arabidopsis cells in culture.

  Molecular plant 20090501

• Molecular basis of antimony treatment in leishmaniasis.

  Journal of medicinal chemistry 20090423

• Functionally important conformations of the Met20 loop in dihydrofolate reductase are populated by rapid thermal fluctuations.

  Journal of the American Chemical Society 20090422

• Inositol 1,4,5-triphosphate receptors and NAD(P)H mediate Ca2+ signaling required for hypoxic preconditioning of hippocampal neurons.

  Neuroscience 20090421

• Mechanism of dihydrouridine synthase 2 from yeast and the importance of modifications for efficient tRNA reduction.

  The Journal of biological chemistry 20090417

• X-ray-radiation-induced cooperative atomic movements in protein.

  Journal of molecular biology 20090417

• Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.

  Journal of molecular biology 20090417

• NADPH is an allosteric regulator of HSCARG.

  Journal of molecular biology 20090417

• Sulforaphane protects astrocytes against oxidative stress and delayed death caused by oxygen and glucose deprivation.

  Glia 20090415

• The peroxidase and peroxynitrite reductase activity of human erythrocyte peroxiredoxin 2.

  Archives of biochemistry and biophysics 20090415

• Personalized metabolic assessment of erythrocytes using microfluidic delivery to an array of luminescent wells.

  Analytical chemistry 20090415

• Cancer. Puzzling patterns of predisposition.

  Science (New York, N.Y.) 20090410

• Purification, characterization and crystallization of pyrroline-5-carboxylate reductase from the hyperthermophilic archeon Sulfolobus Solfataricus.

  Protein expression and purification 20090401

• NAADP-mediated channel 'chatter' in neurons of the rat medulla oblongata.

  The Biochemical journal 20090401

• Differential time- and NADPH-dependent inhibition of CYP2C19 by enantiomers of fluoxetine.

  Drug metabolism and disposition: the biological fate of chemicals 20090401

• Studies of interaction of homo-dimeric ferredoxin-NAD(P)+ oxidoreductases of Bacillus subtilis and Rhodopseudomonas palustris, that are closely related to thioredoxin reductases in amino acid sequence, with ferredoxins and pyridine nucleotide coenzymes.

  Biochimica et biophysica acta 20090401

• Doublecortin expression in adult cat and primate cerebral cortex relates to immature neurons that develop into GABAergic subgroups.

  Experimental neurology 20090401

• Metabolic activation of mifepristone [RU486; 17beta-hydroxy-11beta-(4-dimethylaminophenyl)-17alpha-(1-propynyl)-estra-4,9-dien-3-one] by mammalian cytochromes P450 and the mechanism-based inactivation of human CYP2B6.

  The Journal of pharmacology and experimental therapeutics 20090401

• Impact of overexpressing NADH kinase on glucose and xylose metabolism in recombinant xylose-utilizing Saccharomyces cerevisiae.

  Applied microbiology and biotechnology 20090401

• Triggering and amplification of insulin secretion by dimethyl alpha-ketoglutarate, a membrane permeable alpha-ketoglutarate analogue.

  European journal of pharmacology 20090401

• Identification of a chemical probe for NAADP by virtual screening.

  Nature chemical biology 20090401

• Characterization of two cotton cDNAs encoding trans-2-enoyl-CoA reductase reveals a putative novel NADPH-binding motif.

  Journal of experimental botany 20090401

• A novel vanadium reductase, Vanabin2, forms a possible cascade involved in electron transfer.

  Biochimica et biophysica acta 20090401

• Detection of free radical reactions in an aqueous sample induced by low linear-energy-transfer irradiation.

  Biological & pharmaceutical bulletin 20090401

• Rat ventral prostate xanthine oxidase-mediated metabolism of acetaldehyde to acetyl radical.

  Human & experimental toxicology 20090401

• Substrate-enzyme competition attenuates upregulated anaplerotic flux through malic enzyme in hypertrophied rat heart and restores triacylglyceride content: attenuating upregulated anaplerosis in hypertrophy.

  Circulation research 20090327

• Innate short-circuiting of mitochondrial metabolism in cardiac hypertrophy: identification of novel consequences of enhanced anaplerosis.

  Circulation research 20090327

• Chebulagic acid (CA) attenuates LPS-induced inflammation by suppressing NF-kappaB and MAPK activation in RAW 264.7 macrophages.

  Biochemical and biophysical research communications 20090327

• Discovery of novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.

  Molecular and cellular endocrinology 20090325

• 11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose.

  Molecular and cellular endocrinology 20090325

• Structure and catalytic mechanism of human steroid 5beta-reductase (AKR1D1).

  Molecular and cellular endocrinology 20090325

• Expression pattern of a chloroplast NADPH-dependent thioredoxin reductase in Chlorella vulgaris during hardening and its interaction with 2-Cys peroxiredoxin.

  Bioscience, biotechnology, and biochemistry 20090323

• Two sources of mitochondrial NADPH in the yeast Saccharomyces cerevisiae.

  The Journal of biological chemistry 20090320

• The glutathione system of Aspergillus nidulans involves a fungus-specific glutathione S-transferase.

  The Journal of biological chemistry 20090320

• Characterization of a rat NADPH-dependent aldo-keto reductase (AKR1B13) induced by oxidative stress.

  Chemico-biological interactions 20090316

• A variety of electrostatic interactions and adducts can activate NAD(P) cofactors for hydride transfer.

  Chemico-biological interactions 20090316

• Biochemical basis for differences in metabolism-dependent genotoxicity by two diazinylpiperazine-based 5-HT2C receptor agonists.

  Bioorganic & medicinal chemistry letters 20090315

• Flexibility in anaerobic metabolism as revealed in a mutant of Chlamydomonas reinhardtii lacking hydrogenase activity.

  The Journal of biological chemistry 20090313

• NO formation by neuronal NO-synthase can be controlled by ultrafast electron injection from a nanotrigger.

  Chembiochem : a European journal of chemical biology 20090302

• Involvement of NOS/NO in the development of chronic dental inflammatory pain in rats.

  Brain research reviews 20090301

• Investigation of the in vitro metabolism of the analgesic flupirtine.

  Drug metabolism and disposition: the biological fate of chemicals 20090301

• Role of cytosolic NADP+-dependent isocitrate dehydrogenase in ischemia-reperfusion injury in mouse kidney.

  American journal of physiology. Renal physiology 20090301

• Mechanisms of fenthion activation in rainbow trout (Oncorhynchus mykiss) acclimated to hypersaline environments.

  Toxicology and applied pharmacology 20090301

• Molecular characterization of the recombinant iron-containing alcohol dehydrogenase from the hyperthermophilic Archaeon, Thermococcus strain ES1.

  Extremophiles : life under extreme conditions 20090301

• Specific inhibition of hypoxia inducible factor 1 exaggerates cell injury induced by in vitro ischemia through deteriorating cellular redox environment.

  Journal of neurochemistry 20090301

• Serotonin binds to purified neuronal nitric oxide synthase: a possible explanation for ROS production induced by 5HT in the presence of nNOS.

  Free radical research 20090301

• The propagation of hamster-adapted scrapie PrPSc can be enhanced by reduced pyridine nucleotide in vitro.

  The FEBS journal 20090301

• Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.

  Acta crystallographica. Section D, Biological crystallography 20090301

• Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation.

  The Biochemical journal 20090215

• Characterization of Nda2, a plastoquinone-reducing type II NAD(P)H dehydrogenase in chlamydomonas chloroplasts.

  The Journal of biological chemistry 20090213

• Engineering of the cofactor specificities and isoform-specific inhibition of malic enzyme.

  The Journal of biological chemistry 20090213

• Emerging roles of NAD+ and its metabolites in cell signaling.

  Science signaling 20090210

• Comparison of the effects of NADH- and NADPH-perturbation stresses on the growth of Escherichia coli.

  Current microbiology 20090201

• Hypoglycaemic, antioxidative and nephroprotective effects of taurine in alloxan diabetic rabbits.

  Biochimie 20090201

• Coenzyme binding and hydride transfer in Rhodobacter capsulatus ferredoxin/flavodoxin NADP(H) oxidoreductase.

  Biochimica et biophysica acta 20090201

• Glucose and pharmacological modulators of ATP-sensitive K+ channels control [Ca2+]c by different mechanisms in isolated mouse alpha-cells.

  Diabetes 20090201

• Structural studies of shikimate dehydrogenase from Bacillus anthracis complexed with cofactor NADP.

  Journal of molecular modeling 20090201

• BLX-1002, a novel thiazolidinedione with no PPAR affinity, stimulates AMP-activated protein kinase activity, raises cytosolic Ca2+, and enhances glucose-stimulated insulin secretion in a PI3K-dependent manner.

  American journal of physiology. Cell physiology 20090201

• NADP-dehydrogenases from pepper fruits: effect of maturation.

  Physiologia plantarum 20090201

• Probing stereoselectivity and pro-chirality of hydride transfer during short-chain alcohol dehydrogenase activity: a combined quantitative 2H NMR and computational approach.

  Archives of biochemistry and biophysics 20090201

• Structural insight into the catalytic mechanism of gluconate 5-dehydrogenase from Streptococcus suis: Crystal structures of the substrate-free and quaternary complex enzymes.

  Protein science : a publication of the Protein Society 20090201

• Comparison of the nicotinamide catabolism among rat strains.

  Bioscience, biotechnology, and biochemistry 20090201

• Cloning, expression, and characterization of a novel diketoreductase from Acinetobacter baylyi.

  Acta biochimica et biophysica Sinica 20090201

• X-ray crystallographic and enzymatic analyses of shikimate dehydrogenase from Staphylococcus epidermidis.

  The FEBS journal 20090201

• Characterization of a novel dithiocarbamate glutathione reductase inhibitor and its use as a tool to modulate intracellular glutathione.

  The Journal of biological chemistry 20090130

• Oscillatory NAD(P)H waves and calcium oscillations in neutrophils? A modeling study of feasibility.

  Biophysical journal 20090121

• The crystal structure of a ternary complex of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa Provides new insight into the reaction mechanism and shows a novel binding mode of the 2'-phosphate of NADP+ and a novel cation binding site.

  Journal of molecular biology 20090116

• Requirement for aralar and its Ca2+-binding sites in Ca2+ signal transduction in mitochondria from INS-1 clonal beta-cells.

  The Journal of biological chemistry 20090102

• Analysis of NADPH supply during xylitol production by engineered Escherichia coli.

  Biotechnology and bioengineering 20090101

• Characterization of coenzyme binding and selectivity determinants in Mycobacterium tuberculosis flavoprotein reductase A: analysis of Arg(199) and Arg(200) mutants at the NADP(H) 2'-phosphate binding site.

  The Biochemical journal 20090101

• An antioxidant redox system in the nucleus of wheat seed cells suffering oxidative stress.

  The Plant journal : for cell and molecular biology 20090101

• Extracellular pyridine nucleotides induce PR gene expression and disease resistance in Arabidopsis.

  The Plant journal : for cell and molecular biology 20090101

• Mediator-assisted simultaneous probing of cytosolic and mitochondrial redox activity in living cells.

  Analytical biochemistry 20090101

• The relationship between pyridine nucleotides and seed dormancy.

  The New phytologist 20090101

• Preferential utilization of NADPH as the endogenous electron donor for NAD(P)H:quinone oxidoreductase 1 (NQO1) in intact pulmonary arterial endothelial cells.

  Free radical biology & medicine 20090101

• Free radical production from the interaction of 2-chloroethyl vesicants (mustard gas) with pyridine nucleotide-driven flavoprotein electron transport systems.

  Toxicology and applied pharmacology 20090101

• Redox warfare between airway epithelial cells and Pseudomonas: dual oxidase versus pyocyanin.

  Immunologic research 20090101

• Could G6PD-Buenos-Aires confirm the existence of the 'structural NADP+ binding site' and its strategic role for the stability and/or activity enzyme?

  Clinical biochemistry 20090101

• Nitroreductive metabolic activation of some carcinogenic nitro heterocyclic food contaminants in rat mammary tissue cellular fractions.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101

• The thioredoxin reductase-glutaredoxins-ferredoxin crossroad pathway for selenate tolerance in Synechocystis PCC6803.

  Molecular microbiology 20090101

• Roles of NAD(+) / NADH and NADP(+) / NADPH in cell death.

  Current pharmaceutical design 20090101

• Photoprotective effect of yellow-tinted intraocular lenses.

  Japanese journal of ophthalmology 20090101

• Investigation of the central carbon metabolism of Sorangium cellulosum: metabolic network reconstruction and quantification of pathway fluxes.

  Journal of microbiology and biotechnology 20090101

• A new strategy to improve the efficiency and sustainability of Candida parapsilosis catalyzing deracemization of (R,S)-1-phenyl-1,2-ethanediol under non-growing conditions: increase of NADPH availability.

  Journal of microbiology and biotechnology 20090101

• A mechanism of efficient G6PD inhibition by a molecular clip.

  Angewandte Chemie (International ed. in English) 20090101

• An optimised system for refolding of human glucose 6-phosphate dehydrogenase.

  BMC biotechnology 20090101

• Hormone-dependent and hormone-independent control of metabolic and developmental functions of malate dehydrogenase - review.

  Endocrine regulations 20090101

• NAD(P) biosynthesis enzymes as potential targets for selective drug design.

  Current medicinal chemistry 20090101

• Stable electroenzymatic processes by catalyst separation.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090101

• Enzyme catalysis 'reilluminated'.

  Angewandte Chemie (International ed. in English) 20090101

• New developments in anthracycline-induced cardiotoxicity.

  Current medicinal chemistry 20090101

• Metabolic impact of redox cofactor perturbations in Saccharomyces cerevisiae.

  Metabolic engineering 20090101

• Study of aerobic granulocyte functional activity in the presence of a radiosensitizer (metronidazole).

  Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20090101

• Proteomic analysis of the rat ovary following chronic low-dose exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

  Journal of toxicology and environmental health. Part A 20090101

• SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis.

  PloS one 20090101

• Enzymatic characterization of a monomeric isocitrate dehydrogenase from Streptomyces lividans TK54.

  Biochimie 20090101

• The effects of Urtica dioica L. leaf extract on aniline 4-hydroxylase in mice.

  Acta poloniae pharmaceutica 20090101

• Design of a cytochrome P450BM3 reaction system linked by two-step cofactor regeneration catalyzed by a soluble transhydrogenase and glycerol dehydrogenase.

  Biotechnology progress 20090101

• Increased expression of the oxidative pentose phosphate pathway and gluconeogenesis in anaerobically growing xylose-utilizing Saccharomyces cerevisiae.

  Microbial cell factories 20090101

• [pH-dependent regulation of electron transport in chloroplasts. Computer simulation investigation].

  Biofizika 20090101

• An ATP and oxalate generating variant tricarboxylic acid cycle counters aluminum toxicity in Pseudomonas fluorescens.

  PloS one 20090101

• Chlorzoxazone hydroxylation in microsomes and hepatocytes from cytochrome P450 oxidoreductase-null mice.

  Journal of biochemical and molecular toxicology 20090101

• Changes in human endothelial cell energy metabolic capacities during in vitro cultivation. The role of 'aerobic glycolysis' and proliferation.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101

• NADPH oxidase expression and production of superoxide by human corneal stromal cells.

  Molecular vision 20090101

• Glucose metabolism, islet architecture, and genetic homogeneity in imprinting of [Ca2+](i) and insulin rhythms in mouse islets.

  PloS one 20090101

• Methanol extract of Ocimum gratissimum protects murine peritoneal macrophages from nicotine toxicity by decreasing free radical generation, lipid and protein damage and enhances antioxidant protection.

  Oxidative medicine and cellular longevity 20090101

• Oxidative stress as a mediator of cardiovascular disease.

  Oxidative medicine and cellular longevity 20090101

• Insulin receptor signaling for the proliferation of pancreatic β-cells: involvement of Ca2+ second messengers, IP3, NAADP and cADPR.

  Islets 20090101

• Hydride transfer made easy in the reaction of alcohol oxidation catalyzed by flavin-dependent oxidases.

  Biochemistry 20081230

• Molecular cloning and characterization of a candidate human growth-related and time-keeping constitutive cell surface hydroquinone (NADH) oxidase.

  Biochemistry 20081230

• Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition.

  Biochemistry 20081223

• Correction of pre-steady-state KIEs for isotopic impurities and the consequences of kinetic isotope fractionation.

  The journal of physical chemistry. A 20081218

• Effect of nitric oxide on auditory cortical neurons of aged rats.

  Neuroscience letters 20081205

• Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils.

  Cell calcium 20081201

• Role of residues in the adenosine binding site of NAD of the Ascaris suum malic enzyme.

  Biochimica et biophysica acta 20081201

• Nonenzymatic formation of a novel hydroxylated sulfamethoxazole derivative in human liver microsomes: implications for bioanalysis of sulfamethoxazole metabolites.

  Drug metabolism and disposition: the biological fate of chemicals 20081201

• Purification and characterization of flavin-containing monooxygenase isoform 3 from rat kidney microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20081201

• 2-Diethylaminoethyl-2,2-diphenylvalerate-HCl (SKF525A) revisited: comparative cytochrome P450 inhibition in human liver microsomes by SKF525A, its metabolites, and SKF-acid and SKF-alcohol.

  Drug metabolism and disposition: the biological fate of chemicals 20081201

• Structural characterization of novel adenine dinucleotide phosphate conjugates of imatinib in incubations with rat and human liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20081201

• Malic enzyme is present in mouse islets and modulates insulin secretion.

  Diabetologia 20081201

• Multiple gene-mediated NAD(P)H-dependent aldehyde reduction is a mechanism of in situ detoxification of furfural and 5-hydroxymethylfurfural by Saccharomyces cerevisiae.

  Applied microbiology and biotechnology 20081201

• Separation of flavins and nicotinamide cofactors in Chinese hamster ovary cells by capillary electrophoresis.

  Biomedical chromatography : BMC 20081201

• Mechanism of alcohol-induced oxidative stress and neuronal injury.

  Free radical biology & medicine 20081201

• Oxytocin attenuates NADPH-dependent superoxide activity and IL-6 secretion in macrophages and vascular cells.

  American journal of physiology. Endocrinology and metabolism 20081201

• The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: a review.

  Journal of inherited metabolic disease 20081201

• The unexplored potential of the pentose phosphate pathway in health and disease.

  Journal of inherited metabolic disease 20081201

• Reduction of aliphatic nitroesters and N-nitramines by Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase: quantitative structure-activity relationships.

  The FEBS journal 20081201

• Inhibitory effect of green tea extract and (-)-epigallocatechin-3-gallate on mammalian thioredoxin reductase and HeLa cell viability.

  Oncology reports 20081201

• The expression pattern of NAD(P)H oxidases and the cyclic electron transport pathway around photosystem I of Synechocystis sp. PCC6803 depend on growth conditions.

  Bioscience, biotechnology, and biochemistry 20081201

• Impeded electron transfer from a pathogenic FMN domain mutant of methionine synthase reductase and its responsiveness to flavin supplementation.

  Biochemistry 20081125

• Overexpression of glucose-6-phosphate dehydrogenase extends the life span of Drosophila melanogaster.

  The Journal of biological chemistry 20081121

• Altered NAD(P)H production in neonatal rat islets resistant to H2O2.

  Life sciences 20081121

• Impaired redox state and respiratory chain enzyme activities in the cerebellum of vitamin A-treated rats.

  Toxicology 20081120

• Ferritin, a protein containing iron nanoparticles, induces reactive oxygen species formation and inhibits glutamate uptake in rat brain synaptosomes.

  Brain research 20081119

• Structural insight into bioremediation of triphenylmethane dyes by Citrobacter sp. triphenylmethane reductase.

  The Journal of biological chemistry 20081114

• Defining the in Vivo Role for cytochrome b5 in cytochrome P450 function through the conditional hepatic deletion of microsomal cytochrome b5.

  The Journal of biological chemistry 20081114

• Two photon-induced electron injection from a nanotrigger in native endothelial NO-synthase.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20081110

• NAADP: a universal Ca2+ trigger.

  Science signaling 20081104

• Reductive inactivation of yeast glutathione reductase by Fe(II) and NADPH.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20081101

• The NprA nitroreductase required for 2,4-dinitrophenol reduction in Rhodobacter capsulatus is a dihydropteridine reductase.

  Environmental microbiology 20081101

• Niacin deficiency causes oxidative stress in rat bone marrow cells but not through decreased NADPH or glutathione status.

  The Journal of nutritional biochemistry 20081101

• Dietary supplementation with cholesterol and docosahexaenoic acid increases the activity of the arginine-nitric oxide pathway in tissues of young pigs.

  Nitric oxide : biology and chemistry 20081101

• Activation of macrophages and lymphocytes by methylglyoxal against tumor cells in the host.

  International immunopharmacology 20081101

• Expression of protein engineered NADP+-dependent xylitol dehydrogenase increases ethanol production from xylose in recombinant Saccharomyces cerevisiae.

  Applied microbiology and biotechnology 20081101

• Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension.

  American journal of physiology. Lung cellular and molecular physiology 20081101

• Structure of aldehyde reductase in ternary complex with coenzyme and the potent 20alpha-hydroxysteroid dehydrogenase inhibitor 3,5-dichlorosalicylic acid: implications for inhibitor binding and selectivity.

  Archives of biochemistry and biophysics 20081101

• Investigating cADPR and NAADP in intact and broken cell preparations.

  Methods (San Diego, Calif.) 20081101

• Replacing Escherichia coli NAD-dependent glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with a NADP-dependent enzyme from Clostridium acetobutylicum facilitates NADPH dependent pathways.

  Metabolic engineering 20081101

• Calcium-dependent activation of mitochondrial metabolism in mammalian cells.

  Methods (San Diego, Calif.) 20081101

• Carbon source-dependent modulation of NADP-glutamate dehydrogenases in isophthalate-degrading Pseudomonas aeruginosa strain PP4, Pseudomonas strain PPD and Acinetobacter lwoffii strain ISP4.

  Microbiology (Reading, England) 20081101

• Possible mechanisms for the anticonvulsant activity of fructose-1,6-diphosphate.

  Epilepsia 20081101

• Acetaldehyde tolerance in Saccharomyces cerevisiae involves the pentose phosphate pathway and oleic acid biosynthesis.

  Yeast (Chichester, England) 20081101

• Orchestration of concurrent oxidation and reduction cycles for stereoinversion and deracemisation of sec-alcohols.

  Journal of the American Chemical Society 20081022

• Surface sites for engineering allosteric control in proteins.

  Science (New York, N.Y.) 20081017

• Nitric oxide (NO) increase at fertilization in sea urchin eggs upregulates fertilization envelope hardening.

  Developmental biology 20081015

• Conformational events during ternary enzyme-substrate complex formation are rate limiting in the catalytic cycle of the light-driven enzyme protochlorophyllide oxidoreductase.

  Biochemistry 20081014

• Regulation of nuclear Ca2+ signaling by translocation of the Ca2+ messenger synthesizing enzyme ADP-ribosyl cyclase during neuronal depolarization.

  The Journal of biological chemistry 20081010

• A pronounced light-induced zeaxanthin formation accompanied by an unusually slight increase in non-photochemical quenching: a study with barley leaves treated with methyl viologen at moderate light.

  Journal of plant physiology 20081009

• Catalytic cycle of human glutathione reductase near 1 A resolution.

  Journal of molecular biology 20081003

• Redox-independent activation of NF-kappaB by Pseudomonas aeruginosa pyocyanin in a cystic fibrosis airway epithelial cell line.

  The Journal of biological chemistry 20081003

• Rapid mechanisms of glucocorticoid signaling in the Leydig cell.

  Steroids 20081001

• Transformation and actions of extracellular NADP(+) in the rat liver.

  Molecular and cellular biochemistry 20081001

• Enzymatic reduction of labile iron by organelles of the rat liver. Superior role of an NADH-dependent activity in the outer mitochondrial membrane.

  Biochimie 20081001

• Application of comparative proteome analysis to reveal influence of cultivation conditions on asymmetric bioreduction of beta-keto ester by Saccharomyces cerevisiae.

  Applied microbiology and biotechnology 20081001

• Deciphering the key residues in Plasmodium falciparum beta-ketoacyl acyl carrier protein reductase responsible for interactions with Plasmodium falciparum acyl carrier protein.

  The FEBS journal 20081001

• Oxidative stress by Helicobacter pylori causes apoptosis through mitochondrial pathway in gastric epithelial cells.

  Apoptosis : an international journal on programmed cell death 20081001

• Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.

  Bioorganic & medicinal chemistry 20081001

• The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.

  Hepatology (Baltimore, Md.) 20081001

• The Pseudomonas toxin pyocyanin inhibits the dual oxidase-based antimicrobial system as it imposes oxidative stress on airway epithelial cells.

  Journal of immunology (Baltimore, Md. : 1950) 20081001

• Metabolic response of Pseudomonas putida during redox biocatalysis in the presence of a second octanol phase.

  The FEBS journal 20081001

• Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle.

  Nature genetics 20081001

• Inhibition of heme oxygenase activity in newborn mice by azalanstat.

  Canadian journal of physiology and pharmacology 20081001

• A cytosolic pathway for the conversion of hydroxypyruvate to glycerate during photorespiration in Arabidopsis.

  The Plant cell 20081001

• Proton-translocating transhydrogenase: an update of unsolved and controversial issues.

  Journal of bioenergetics and biomembranes 20081001

• Structural organization of photosynthetic apparatus in agranal chloroplasts of maize.

  The Journal of biological chemistry 20080919

• Thioredoxin reductase from Thermoplasma acidophilum: a new twist on redox regulation.

  Biochemistry 20080916

• Dysregulation of antioxidant mechanisms contributes to increased oxidative stress in calcific aortic valvular stenosis in humans.

  Journal of the American College of Cardiology 20080902

• Ethanol induces peroxynitrite-mediated toxicity through inactivation of NADP+-dependent isocitrate dehydrogenase and superoxide dismutase.

  Biochimie 20080901

• Nitrotyrosine promotes human aortic smooth muscle cell migration through oxidative stress and ERK1/2 activation.

  Biochimica et biophysica acta 20080901

• Important amino acid residues that confer CYP2C19 selective activity to CYP2C9.

  Journal of biochemistry 20080901

• Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction.

  Protein science : a publication of the Protein Society 20080901

• GR24, a synthetic analog of strigolactones, stimulates the mitosis and growth of the arbuscular mycorrhizal fungus Gigaspora rosea by boosting its energy metabolism.

  Plant physiology 20080901

• Geobacter sulfurreducens strain engineered for increased rates of respiration.

  Metabolic engineering 20080901

• Noninvasive metabolic profiling using microfluidics for analysis of single preimplantation embryos.

  Analytical chemistry 20080901

• Inter-flavin electron transfer in cytochrome P450 reductase - effects of solvent and pH identify hidden complexity in mechanism.

  The FEBS journal 20080901

• Oxidative stress-associated impairment of glucose and ammonia metabolism in the filamentous fungus, Aspergillus niger B1-D.

  Mycological research 20080901

• Structural analysis of a holoenzyme complex of mouse dihydrofolate reductase with NADPH and a ternary complex with the potent and selective inhibitor 2,4-diamino-6-(2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine.

  Acta crystallographica. Section D, Biological crystallography 20080901

• Glucose-6-phosphate dehydrogenase: a novel therapeutic target in cardiovascular diseases.

  Current opinion in investigational drugs (London, England : 2000) 20080901

• Enzymatic properties of terephthalate 1,2-dioxygenase of Comamonas sp. strain E6.

  Bioscience, biotechnology, and biochemistry 20080901

• Kinetic study of cytochrome P450 by capillary electrophoretically mediated microanalysis.

  Electrophoresis 20080901

• alpha-Ketoglutarate biosynthesis in wild and industrial strains of Lactococcus lactis.

  Letters in applied microbiology 20080901

• Constructing and testing the thermodynamic limits of synthetic NAD(P)H:H2 pathways.

  Microbial biotechnology 20080901

• Structural analysis of the recognition of the negative regulator NmrA and DNA by the zinc finger from the GATA-type transcription factor AreA.

  Journal of molecular biology 20080829

• Catalytic mechanism and substrate specificity of the beta-subunit of the voltage-gated potassium channel.

  Biochemistry 20080826

• Glutathione reductase and thioredoxin reductase at the crossroad: the structure of Schistosoma mansoni thioredoxin glutathione reductase.

  Proteins 20080815

• Chemical proteomics-based drug design: target and antitarget fishing with a catechol-rhodanine privileged scaffold for NAD(P)(H) binding proteins.

  Journal of medicinal chemistry 20080814

• X-ray crystallographic and solution state nuclear magnetic resonance spectroscopic investigations of NADP+ binding to ferredoxin NADP reductase from Pseudomonas aeruginosa.

  Biochemistry 20080805

• Secondary kinetic isotope effects as probes of environmentally-coupled enzymatic hydrogen tunneling reactions.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20080804

• Lysosomes co-localize with ryanodine receptor subtype 3 to form a trigger zone for calcium signalling by NAADP in rat pulmonary arterial smooth muscle.

  Cell calcium 20080801

• Structural studies of shikimate 5-dehydrogenase from Mycobacterium tuberculosis.

  Proteins 20080801

• NAADP-induced Ca(2+ signaling in response to endothelin is via the receptor subtype B and requires the integrity of lipid rafts/caveolae.

  Journal of cellular physiology 20080801

• Direct protein-protein interaction of 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the endoplasmic reticulum lumen.

  Biochimica et biophysica acta 20080801

• Elevated activity of the oxidative and non-oxidative pentose phosphate pathway in (pre)neoplastic lesions in rat liver.

  International journal of experimental pathology 20080801

• Age-related decreases in NAD(P)H and glutathione cause redox declines before ATP loss during glutamate treatment of hippocampal neurons.

  Journal of neuroscience research 20080801

• Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition.

  Free radical biology & medicine 20080801

• Saturation transfer difference NMR studies on substrates and inhibitors of succinic semialdehyde dehydrogenases.

  Biochemical and biophysical research communications 20080801

• What is the role of the second 'structural' NADP+-binding site in human glucose 6-phosphate dehydrogenase?

  Protein science : a publication of the Protein Society 20080801

• Purification and characterization of glutathione reductase from rainbow trout (Oncorhynchus mykiss) liver and inhibition effects of metal ions on enzyme activity.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080801

• Crystal structure of a carbonyl reductase from Candida parapsilosis with anti-Prelog stereospecificity.

  Protein science : a publication of the Protein Society 20080801

• Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice.

  Hypertension (Dallas, Tex. : 1979) 20080801

• Septic impairment of capillary blood flow requires nicotinamide adenine dinucleotide phosphate oxidase but not nitric oxide synthase and is rapidly reversed by ascorbate through an endothelial nitric oxide synthase-dependent mechanism.

  Critical care medicine 20080801

• Metyrapone prevents cortisone-induced preadipocyte differentiation by depleting luminal NADPH of the endoplasmic reticulum.

  Biochemical pharmacology 20080801

• In vitro stimulatory effect of anti-apoptotic seminal vesicle protein 4 on purified peroxidase enzymes.

  The FEBS journal 20080801

• Structure-guided alteration of coenzyme specificity of formate dehydrogenase by saturation mutagenesis to enable efficient utilization of NADP+.

  The FEBS journal 20080801

• Microcin J25 induces the opening of the mitochondrial transition pore and cytochrome c release through superoxide generation.

  The FEBS journal 20080801

• Structural evidence for the inhibition of grape dihydroflavonol 4-reductase by flavonols.

  Acta crystallographica. Section D, Biological crystallography 20080801

• Expression, purification, crystallization and preliminary X-ray analysis of an NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Helicobacter pylori.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20080801

• [Metabolic flux analysis of L-threonine biosynthesis strain under diverse dissolved oxygen conditions].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20080801

• Differences in a conformational equilibrium distinguish catalysis by the endothelial and neuronal nitric-oxide synthase flavoproteins.

  The Journal of biological chemistry 20080711

• Isoporphyrin intermediate in heme oxygenase catalysis. Oxidation of alpha-meso-phenylheme.

  The Journal of biological chemistry 20080711

• Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate.

  Journal of molecular biology 20080711

• Regulation of eNOS-derived superoxide by endogenous methylarginines.

  Biochemistry 20080708

• Microdosing assessment to evaluate pharmacokinetics and drug metabolism in rats using liquid chromatography-tandem mass spectrometry.

  Pharmaceutical research 20080701

• Deficiency in cytosolic malic enzyme does not increase acetaminophen-induced hepato-toxicity.

  Basic & clinical pharmacology & toxicology 20080701

• NTRC new ways of using NADPH in the chloroplast.

  Physiologia plantarum 20080701

• Determination of the cytosolic free NAD/NADH ratio in Saccharomyces cerevisiae under steady-state and highly dynamic conditions.

  Biotechnology and bioengineering 20080701

• Histochemical staining of rectal suction biopsies as the first investigation in patients with chronic constipation.

  Pediatric surgery international 20080701

• Interactions between cell death induced by statins and 7-ketocholesterol in rabbit aorta smooth muscle cells.

  British journal of pharmacology 20080701

• Brain angiotensin enhances dopaminergic cell death via microglial activation and NADPH-derived ROS.

  Neurobiology of disease 20080701

• [Suppression of cell proliferation by inhibitors to redox signaling in human lens epithelial cells].

  [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20080701

• Simultaneous determination of cell aging and ATP release from erythrocytes and its implications in type 2 diabetes.

  Analytica chimica acta 20080623

• Biological roles for the NOX family NADPH oxidases.

  The Journal of biological chemistry 20080620

• Kinetic and mechanistic analysis of the Escherichia coli ribD-encoded bifunctional deaminase-reductase involved in riboflavin biosynthesis.

  Biochemistry 20080617

• Structural and functional diversity of ferredoxin-NADP(+) reductases.

  Archives of biochemistry and biophysics 20080615

• Metabolic fluxes and stoichiometry of glucose metabolism.

  Biophysical journal 20080615

• Variability of the response of Saccharomyces cerevisiae strains to lignocellulose hydrolysate.

  Biotechnology and bioengineering 20080615

• Structural enzymological studies of 2-enoyl thioester reductase of the human mitochondrial FAS II pathway: new insights into its substrate recognition properties.

  Journal of molecular biology 20080613

• Maintenance of luminal NADPH in the endoplasmic reticulum promotes the survival of human neutrophil granulocytes.

  FEBS letters 20080611

• On the functional role of a water molecule in clade 3 catalases: a proposal for the mechanism by which NADPH prevents the formation of compound II.

  Journal of the American Chemical Society 20080611

• Structural and biochemical characterization of a novel aldehyde dehydrogenase encoded by the benzoate oxidation pathway in Burkholderia xenovorans LB400.

  Journal of molecular biology 20080606

• Cell-permeant NAADP: a novel chemical tool enabling the study of Ca2+ signalling in intact cells.

  Cell calcium 20080601

• Toxoplasma gondii ferredoxin-NADP+ reductase: Role of ionic interactions in stabilization of native conformation and structural cooperativity.

  Proteins 20080601

• Hyperbaric oxygenation reduces overexpression of c-Fos and oxidative stress in the brain stem of experimental endotoxemic rats.

  Intensive care medicine 20080601

• The role of glutathione reductase in the interplay between oxidative stress response and turnover of cytosolic NADPH in Kluyveromyces lactis.

  FEMS yeast research 20080601

• The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080601

• Coordinated upregulation of a series of endogenous antioxidants and phase 2 enzymes as a novel strategy for protecting renal tubular cells from oxidative and electrophilic stress.

  Experimental biology and medicine (Maywood, N.J.) 20080601

• Effects of homocysteine on metabolic pathways in cultured astrocytes.

  Neurochemistry international 20080601

• Proteomic and metabolomic analyses of the white-rot fungus Phanerochaete chrysosporium exposed to exogenous benzoic acid.

  Journal of proteome research 20080601

• Antizyme suppression leads to an increment of the cellular redox potential and an induction of HIF-1alpha: its involvement in resistance to gamma-radiation.

  IUBMB life 20080601

• NADPH- and iron-dependent lipid peroxidation inhibit aromatase activity in human placental microsomes.

  The Journal of steroid biochemistry and molecular biology 20080601

• Demonstration by redox fluorometry that sulforaphane protects retinal pigment epithelial cells against oxidative stress.

  Investigative ophthalmology & visual science 20080601

• In vitro characterization of the enzymes involved in the metabolism of 1-furan-2-yl-3-pyridin-2-yl-propenone, an anti-inflammatory propenone compound.

  Archives of pharmacal research 20080601

• [Mutational research on the role of lysine 21 in the Pichia stipitis xylose reductase].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20080601

• Crystal structure of a new type of NADPH-dependent quinone oxidoreductase (QOR2) from Escherichia coli.

  Journal of molecular biology 20080530

• Dissociation of superoxide production by mitochondrial complex I from NAD(P)H redox state.

  FEBS letters 20080528

• Anionic phospholipid-induced regulation of reactive oxygen species production by human cytochrome P450 2E1.

  FEBS letters 20080528

• Structure of 2,6-dihydroxypyridine 3-hydroxylase from a nicotine-degrading pathway.

  Journal of molecular biology 20080523

• Carbon-deuterium bonds as probes of dihydrofolate reductase.

  Journal of the American Chemical Society 20080521

• Barley aldose reductase: structure, cofactor binding, and substrate recognition in the aldo/keto reductase 4C family.

  Proteins 20080515

• Irrigation with diluted seawater improves the nutritional value of cherry tomatoes.

  Journal of agricultural and food chemistry 20080514

• Pyridine nucleotide complexes with Bacillus anthracis coenzyme A-disulfide reductase: a structural analysis of dual NAD(P)H specificity.

  Biochemistry 20080506

• Revealing the moonlighting role of NADP in the structure of a flavin-containing monooxygenase.

  Proceedings of the National Academy of Sciences of the United States of America 20080506

• Increase in intracellular free/bound NAD[P]H as a cause of Cd-induced oxidative stress in the HepG(2) cells.

  Toxicology 20080502

• Salivary aldehyde dehydrogenase--reversible oxidation of the enzyme and its inhibition by caffeine, investigated using fluorimetric method.

  Archives of oral biology 20080501

• Site-directed mutagenesis of substrate binding sites of azoreductase from Rhodobacter sphaeroides.

  Biotechnology letters 20080501

• Computational and experimental studies on the catalytic mechanism of biliverdin-IXbeta reductase.

  The Biochemical journal 20080501

• The roles of Tyr(91) and Lys(162) in general acid-base catalysis in the pigeon NADP+-dependent malic enzyme.

  The Biochemical journal 20080501

• Characterization of dihydrodipicolinate reductase from Thermotoga maritima reveals evolution of substrate binding kinetics.

  Journal of biochemistry 20080501

• Hymenolepis diminuta: mitochondrial transhydrogenase as an additional site for anaerobic phosphorylation.

  Experimental parasitology 20080501

• Effect of diazoxide on flavoprotein oxidation and reactive oxygen species generation during ischemia-reperfusion: a study on Langendorff-perfused rat hearts using optic fibers.

  American journal of physiology. Heart and circulatory physiology 20080501

• Glucose 6-phosphate dehydrogenase from larval Taenia crassiceps (cysticerci): purification and properties.

  Parasitology research 20080501

• Nicorandil and ulcerations: a NAD/NADP and nicotinic acid-dependent side-effect?

  The British journal of dermatology 20080501

• Nitric oxide degradation by potato tuber mitochondria: evidence for the involvement of external NAD(P)H dehydrogenases.

  Biochimica et biophysica acta 20080501

• Feedback regulation of photosynthetic electron transport by NADP(H) redox poise.

  Biochimica et biophysica acta 20080501

• Characterization of factors affecting the activity of photosystem I cyclic electron transport in chloroplasts.

  Plant & cell physiology 20080501

• The endogenous adrenodoxin reductase-like flavoprotein arh1 supports heterologous cytochrome P450-dependent substrate conversions in Schizosaccharomyces pombe.

  FEMS yeast research 20080501

• Reconciling the chemistry and biology of reactive oxygen species.

  Nature chemical biology 20080501

• Mangifera indica L. extract (Vimang) and its main polyphenol mangiferin prevent mitochondrial oxidative stress in atherosclerosis-prone hypercholesterolemic mouse.

  Pharmacological research 20080501

• Enzymology of mammalian NAD metabolism in health and disease.

  Frontiers in bioscience : a journal and virtual library 20080501

• A classification of NOergic neurons in the inferior colliculus of rat according to co-existence with classical amino acid transmitters.

  Okajimas folia anatomica Japonica 20080501

• Human neutrophils convert the sebum-derived polyunsaturated fatty acid Sebaleic acid to a potent granulocyte chemoattractant.

  The Journal of biological chemistry 20080425

• A substitutive substrate for measurements of beta-ketoacyl reductases in two fatty acid synthase systems.

  Journal of biochemical and biophysical methods 20080424

• The critical role of substrate-protein hydrogen bonding in the control of regioselective hydroxylation in p450cin.

  The Journal of biological chemistry 20080418

• P450cam biocatalysis in surfactant-stabilized two-phase emulsions.

  Biotechnology and bioengineering 20080415

• Non-equivalence of hydrogen transfer from glucose to the pro-R and pro-S methylene positions of ethanol during fermentation by Leuconostoc mesenteroides quantified by 2H NMR at natural abundance.

  The Journal of biological chemistry 20080411

• Synthesis and biological activity of a 3,4,5-trimethoxybenzoyl ester analogue of epicatechin-3-gallate.

  Journal of medicinal chemistry 20080410

• Beneficial effects of diclofenac therapy on serum lipids, oxidized low-density lipoprotein and antioxidant defenses in rats.

  Life sciences 20080409

• Molecular cloning and characterization of CYP80G2, a cytochrome P450 that catalyzes an intramolecular C-C phenol coupling of (S)-reticuline in magnoflorine biosynthesis, from cultured Coptis japonica cells.

  The Journal of biological chemistry 20080404

• Synthesis, physicochemical properties and in vitro cytotoxicity of nicotinic acid ester prodrugs intended for pulmonary delivery using perfluorooctyl bromide as vehicle.

  International journal of pharmaceutics 20080402

• Piper longum Linn. Extract inhibits TNF-alpha-induced expression of cell adhesion molecules by inhibiting NF-kappaB activation and microsomal lipid peroxidation.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20080401

• NAADP+ is an agonist of the human P2Y11 purinergic receptor.

  Cell calcium 20080401

• The photoenzymatic cycle of NADPH: protochlorophyllide oxidoreductase in primary bean leaves (Phaseolus vulgaris) during the first days of photoperiodic growth.

  Photosynthesis research 20080401

• Analysis of metabolic flux in Escherichia coli expressing human-like collagen in fed-batch culture.

  Biotechnology letters 20080401

• Identification by gene deletion analysis of barS2, a gene involved in the biosynthesis of gamma-butyrolactone autoregulator in Streptomyces virginiae.

  Archives of microbiology 20080401

• Redox status of thioredoxin-1 (TRX1) determines the sensitivity of human liver carcinoma cells (HepG2) to arsenic trioxide-induced cell death.

  Cell research 20080401

• Excess copper induces anoxygenic photosynthesis in Anabaena doliolum: a homology based proteomic assessment of its survival strategy.

  Photosynthesis research 20080401

• BYK191023 (2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3h-imidazo[4,5-b]pyridine) is an NADPH- and time-dependent irreversible inhibitor of inducible nitric-oxide synthase.

  Molecular pharmacology 20080401

• Generation of nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose by glucagon-like peptide-1 evokes Ca2+ signal that is essential for insulin secretion in mouse pancreatic islets.

  Diabetes 20080401

• Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: possible mechanisms involved.

  Toxicology in vitro : an international journal published in association with BIBRA 20080401

• Reduction of hypervalent states of myoglobin and hemoglobin to their ferrous forms by thymoquinone: the role of GSH, NADH and NADPH.

  Biochimica et biophysica acta 20080401

• The utilization of bathocuproinedisulfonic acid as a reagent for determining D-glucose and D-galactose levels in glycoconjugates.

  Bioorganic chemistry 20080401

• Molecular modelling and comparative structural account of aspartyl beta-semialdehyde dehydrogenase of Mycobacterium tuberculosis (H37Rv).

  Journal of molecular modeling 20080401

• Modulation of NMDA receptors by intrathecal administration of the sensory neuron-specific receptor agonist BAM8-22.

  Neuropharmacology 20080401

• Chemoenzymatic synthesis of the chiral side-chain of statins: application of an alcohol dehydrogenase catalysed ketone reduction on a large scale.

  Bioprocess and biosystems engineering 20080401

• Epigallocatechin-3-gallate reduces retinal ischemia/reperfusion injury by attenuating neuronal nitric oxide synthase expression and activity.

  Experimental eye research 20080401

• Catechin gallates are NADP+-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP+ as a coenzyme.

  Bioorganic & medicinal chemistry 20080401

• Computer simulation of heterogeneous single nucleotide polymorphisms in the catalase gene indicates structural changes in the enzyme active site, NADPH-binding and tetramerization domains: a genetic predisposition for an altered catalase in patients with vitiligo?

  Experimental dermatology 20080401

• Kinetic mechanism of phenylacetone monooxygenase from Thermobifida fusca.

  Biochemistry 20080401

• NADH- vs NADPH-coupled reduction of 5-hydroxymethyl furfural (HMF) and its implications on product distribution in Saccharomyces cerevisiae.

  Applied microbiology and biotechnology 20080401

• Ca2+ signalling: a new route to NAADP.

  The Biochemical journal 20080401

• Coronary constriction to angiotensin II is enhanced by endothelial superoxide production in sheep programmed by dexamethasone.

  Pediatric research 20080401

• Structure and function of NAD kinase and NADP phosphatase: key enzymes that regulate the intracellular balance of NAD(H) and NADP(H).

  Bioscience, biotechnology, and biochemistry 20080401

• 7-nitroindazole attenuates 6-hydroxydopamine-induced spatial learning deficits and dopamine neuron loss in a presymptomatic animal model of Parkinson's disease.

  Experimental and clinical psychopharmacology 20080401

• The subnanometer resolution structure of the glutamate synthase 1.2-MDa hexamer by cryoelectron microscopy and its oligomerization behavior in solution: functional implications.

  The Journal of biological chemistry 20080328

• Deletion of hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy.

  The Journal of biological chemistry 20080328

• Functional coupling between the Kv1.1 channel and aldoketoreductase Kvbeta1.

  The Journal of biological chemistry 20080328

• Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel.

  Biochemistry 20080325

• Effect of salt and pH on the reductive half-reaction of Mycobacterium tuberculosis FprA with NADPH.

  Biochemistry 20080318

• Isocitrate dehydrogenase: A NADPH-generating enzyme in the lumen of the endoplasmic reticulum.

  Archives of biochemistry and biophysics 20080315

• Adaptation to hydrogen peroxide in Saccharomyces cerevisiae: the role of NADPH-generating systems and the SKN7 transcription factor.

  Free radical biology & medicine 20080315

• TIC62 redox-regulated translocon composition and dynamics.

  The Journal of biological chemistry 20080314

• Characterization of NAD uptake in mammalian cells.

  The Journal of biological chemistry 20080307

• Light-driven biocatalytic oxidation and reduction reactions: scope and limitations.

  Chembiochem : a European journal of chemical biology 20080303

• Glucose utilization of strains lacking PGI1 and expressing a transhydrogenase suggests differences in the pentose phosphate capacity among Saccharomyces cerevisiae strains.

  FEMS yeast research 20080301

• Statin-induced heme oxygenase-1 increases NF-kappaB activation and oxygen radical production in cultured neuronal cells exposed to lipopolysaccharide.

  Toxicological sciences : an official journal of the Society of Toxicology 20080301

• Mycobacterium tuberculosis beta-ketoacyl-ACP reductase: alpha-secondary kinetic isotope effects and kinetic and equilibrium mechanisms of substrate binding.

  Archives of biochemistry and biophysics 20080301

• Enhancement of coenzyme binding by a single point mutation at the coenzyme binding domain of E. coli lactaldehyde dehydrogenase.

  Protein science : a publication of the Protein Society 20080301

• A 3D QSAR model of 17beta-HSD1 inhibitors based on a thieno[2,3-d]pyrimidin-4(3H)-one core applying molecular dynamics simulations and ligand-protein docking.

  ChemMedChem 20080301

• NADH dehydrogenase deficiency results in low respiration rate and improved aerobic growth of Zymomonas mobilis.

  Microbiology (Reading, England) 20080301

• Bioethanol production from xylose by recombinant Saccharomyces cerevisiae expressing xylose reductase, NADP(+)-dependent xylitol dehydrogenase, and xylulokinase.

  Journal of bioscience and bioengineering 20080301

• Novel dehydrogenase catalyzes oxidative hydrolysis of carbon-nitrogen double bonds for hydrazone degradation.

  The Journal of biological chemistry 20080227

• Vasoactivity, antioxidant and aphrodisiac properties of Caesalpinia benthamiana roots.

  Journal of ethnopharmacology 20080227

• Redox-dependent changes in molecular properties of mitochondrial apoptosis-inducing factor.

  The Journal of biological chemistry 20080227

• N(G)-aminoguanidines from primary amines and the preparation of nitric oxide synthase inhibitors.

  Journal of medicinal chemistry 20080227

• A balancing act between net uptake of water during dihydrofolate binding and net release of water upon NADPH binding in R67 dihydrofolate reductase.

  The Journal of biological chemistry 20080222

• NADP regulates the yeast GAL induction system.

  Science (New York, N.Y.) 20080222

• Proper orientation of the nicotinamide ring of NADP is important for the precatalytic conformational change in the 6-phosphogluconate dehydrogenase reaction.

  Biochemistry 20080219

• Benidipine, an anti-hypertensive drug, inhibits reactive oxygen species production in polymorphonuclear leukocytes and oxidative stress in salt-loaded stroke-prone spontaneously hypertensive rats.

  European journal of pharmacology 20080202

• Further improvement of phosphite dehydrogenase thermostability by saturation mutagenesis.

  Biotechnology and bioengineering 20080201

• BCG-induced rabbit alveolar macrophages are endowed with strengthened antioxidant metabolic pathways.

  Inflammation 20080201

• The NADPH quinone reductase MdaB confers oxidative stress resistance to Helicobacter hepaticus.

  Microbial pathogenesis 20080201

• Oxidative stress in hypercholesterolemic LDL (low-density lipoprotein) receptor knockout mice is associated with low content of mitochondrial NADP-linked substrates and is partially reversed by citrate replacement.

  Free radical biology & medicine 20080201

• NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences.

  Antioxidants & redox signaling 20080201

• Heterologous expression and characterization of wild-type human cytochrome P450 1A2 without conventional N-terminal modification in Escherichia coli.

  Protein expression and purification 20080201

• Genetic and biochemical characterization of a 4-hydroxybenzoate hydroxylase from Corynebacterium glutamicum.

  Applied microbiology and biotechnology 20080201

• Lipoic acid suppression of neutrophil respiratory burst: effect of NADPH.

  Antioxidants & redox signaling 20080201

• Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47).

  Molecular nutrition & food research 20080201

• The mitochondrial external NADPH dehydrogenase modulates the leaf NADPH/NADP+ ratio in transgenic Nicotiana sylvestris.

  Plant & cell physiology 20080201

• Long chain fatty acyl-CoA modulation of H(2)O (2) release at mitochondrial complex I.

  Journal of bioenergetics and biomembranes 20080201

• Purification and functional characterization of human 11beta hydroxylase expressed in Escherichia coli.

  The FEBS journal 20080201

• 2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer.

  Free radical biology & medicine 20080201

• Lipid peroxidation potential and antioxidants in the heart tissue of beta-alanine- or taurine-treated old rats.

  Journal of nutritional science and vitaminology 20080201

• Production of superoxide anion and hydrogen peroxide by capacitating buffalo (Bubalus bubalis) spermatozoa.

  Animal reproduction science 20080130

• A complex containing PGRL1 and PGR5 is involved in the switch between linear and cyclic electron flow in Arabidopsis.

  Cell 20080125

• Structure-guided engineering of the coenzyme specificity of Pseudomonas fluorescens mannitol 2-dehydrogenase to enable efficient utilization of NAD(H) and NADP(H).

  FEBS letters 20080123

• Harnessing the mechanism of glutathione reductase for synthesis of active site bound metallic nanoparticles and electrical connection to electrodes.

  Journal of the American Chemical Society 20080123

• Kinetic model for Ca2+-induced permeability transition in energized liver mitochondria discriminates between inhibitor mechanisms.

  The Journal of biological chemistry 20080111

• Differential role of NADP+ and NADPH in the activity and structure of GDP-D-mannose 4,6-dehydratase from two chlorella viruses.

  The Journal of biological chemistry 20080104

• Purification and properties of an unusual UDP-glucose dehydrogenase, NADPH-dependent, from Xanthomonas albilineans.

  Microbiological research 20080101

• Hydroxyl radical scavenger ameliorates cisplatin-induced nephrotoxicity by preventing oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria.

  Cancer chemotherapy and pharmacology 20080101

• Inhibition of palmityl carnitine oxidation in rat liver mitochondria by tert-butyl hydroperoxide.

  Physiological research 20080101

• Mutation in G6PD gene leads to loss of cellular control of protein glutathionylation: mechanism and implication.

  Journal of cellular biochemistry 20080101

• Development of an in vitro assay for the investigation of metabolism-induced drug hepatotoxicity.

  Cell biology and toxicology 20080101

• Melatonin pretreatment improves liver function and hepatic perfusion after hemorrhagic shock.

  Shock (Augusta, Ga.) 20080101

• Erythrocyte glutamine depletion, altered redox environment, and pulmonary hypertension in sickle cell disease.

  Blood 20080101

• Fuel-induced amplification of insulin secretion in mouse pancreatic islets exposed to a high sulfonylurea concentration: role of the NADPH/NADP+ ratio.

  Diabetologia 20080101

• Interaction between photosynthesis and respiration in illuminated leaves.

  Mitochondrion 20080101

• Melatonin receptors mediate improvements of liver function but not of hepatic perfusion and integrity after hemorrhagic shock in rats.

  Critical care medicine 20080101

• Laboratory evolution of P450 BM3 for mediated electron transfer yielding an activity-improved and reductase-independent variant.

  Protein engineering, design & selection : PEDS 20080101

• The prediction of the hepatic clearance of tanshinone IIA in rat liver subcellular fractions: accuracy improvement.

  Current drug metabolism 20080101

• Structure, function, and mechanism of cytosolic quinone reductases.

  Vitamins and hormones 20080101

• Effects of D-003, a mixture of very long chain saturated fatty acids, and policosanol on in vivo lipid peroxidation in rats.

  Arzneimittel-Forschung 20080101

• H2O2 generation is decreased by calcium in isolated brain mitochondria.

  Biochimica et biophysica acta 20080101

• Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos.

  Plant physiology and biochemistry : PPB 20080101

• Nicotinic acid adenine dinucleotide phosphate (NAADP) and Ca2+ mobilization.

  Journal of receptor and signal transduction research 20080101

• Antiproliferative activities of resveratrol and related compounds in human hepatocyte derived HepG2 cells are associated with biochemical cell disturbance revealed by fluorescence analyses.

  Biochimie 20080101

• A novel strategy involved in [corrected] anti-oxidative defense: the conversion of NADH into NADPH by a metabolic network.

  PloS one 20080101

• Pancreatic beta-cell purification by altering FAD and NAD(P)H metabolism.

  Experimental diabetes research 20080101

• Glucose metabolism is accelerated by exposure to t-butylhydroperoxide during NADH consumption in human erythrocytes.

  Blood cells, molecules & diseases 20080101

• The scale-free dynamics of eukaryotic cells.

  PloS one 20080101

• Effect of taurine treatment on pro-oxidant-antioxidant balance in livers and brains of old rats.

  Pharmacological reports : PR 20080101

• [Co-adaptation of enzymatic systems of cells and blood supply in smooth muscle tumors of the corpus uteri].

  Voprosy onkologii 20080101

• Bioreduction of idarubicin and formation of ROS responsible for DNA cleavage by NADPH-cytochrome P450 reductase and its potential role in the antitumor effect.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20080101

• Flow cytometric quantification of glucose-stimulated beta-cell metabolic flux can reveal impaired islet functional potency.

  Cell transplantation 20080101

• Comparing flux balance analysis to network expansion: producibility, sustainability and the scope of compounds.

  Genome informatics. International Conference on Genome Informatics 20080101

• The lyngbyatoxin biosynthetic assembly line: chain release by four-electron reduction of a dipeptidyl thioester to the corresponding alcohol.

  Journal of the American Chemical Society 20071226

• Crystal structure of a type II dihydrofolate reductase catalytic ternary complex.

  Biochemistry 20071225

• Stereocomplementary bioreduction of alpha,beta-unsaturated dicarboxylic acids and dimethyl esters using enoate reductases: enzyme- and substrate-based stereocontrol.

  Organic letters 20071220

• Versatile regulation of neuronal nitric oxide synthase by specific regions of its C-terminal tail.

  Biochemistry 20071218

• Multiple roles of arginine 181 in binding and catalysis in the NAD-malic enzyme from Ascaris suum.

  Biochemistry 20071218

• Inhibition on human liver cytochrome P450 3A4 by constituents of fennel (Foeniculum vulgare): identification and characterization of a mechanism-based inactivator.

  Journal of agricultural and food chemistry 20071212

• Transhydrogenation reactions catalyzed by mitochondrial NADH-ubiquinone oxidoreductase (Complex I).

  Biochemistry 20071211

• Overproduction of bioactive retinoic acid in cells expressing disease-associated mutants of retinol dehydrogenase 12.

  The Journal of biological chemistry 20071207

• A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion.

  The Journal of biological chemistry 20071207

• Effect of two intermediate electron donors, NADPH and FADH(2), on Spirulina Delta (6)-desaturase co-expressed with two different immediate electron donors, cytochrome b (5) and ferredoxin, in Escherichia coli.

  Molecular biology reports 20071201

• Nitroaryl-1,4-dihydropyridines as antioxidants against rat liver microsomes oxidation induced by iron/ascorbate, nitrofurantoin and naphthalene.

  Toxicology in vitro : an international journal published in association with BIBRA 20071201

• Progress curve analysis of CYP1A2 inhibition: a more informative approach to the assessment of mechanism-based inactivation?

  Drug metabolism and disposition: the biological fate of chemicals 20071201

• Disifin (sodium tosylchloramide) and Toll-like receptors (TLRs): evolving importance in health and diseases.

  Journal of industrial microbiology & biotechnology 20071201

• In vitro metabolism of the analgesic bicifadine in the mouse, rat, monkey, and human.

  Drug metabolism and disposition: the biological fate of chemicals 20071201

• Reduction in oxalate-induced renal tubular epithelial cell injury by an extract from Quercus salicina Blume/Quercus stenophylla Makino.

  Urological research 20071201

• Refinement of a radioreceptor binding assay for nicotinic acid adenine dinucleotide phosphate.

  Analytical biochemistry 20071201

• Lactate uptake contributes to the NAD(P)H biphasic response and tissue oxygen response during synaptic stimulation in area CA1 of rat hippocampal slices.

  Journal of neurochemistry 20071201

• Phytanic acid impairs mitochondrial respiration through protonophoric action.

  Cellular and molecular life sciences : CMLS 20071201

• Amperometric response from the glycolytic versus the pentose phosphate pathway in Saccharomyces cerevisiae cells.

  Analytical chemistry 20071201

• The major route for chlorophyll synthesis includes [3,8-divinyl]-chlorophyllide a reduction in Arabidopsis thaliana.

  Plant & cell physiology 20071201

• RbrA, a cyanobacterial rubrerythrin, functions as a FNR-dependent peroxidase in heterocysts in protection of nitrogenase from damage by hydrogen peroxide in Anabaena sp. PCC 7120.

  Molecular microbiology 20071201

• Enhanced markers of oxidative stress, altered antioxidants and NADPH-oxidase activation in brains from Fragile X mental retardation 1-deficient mice, a pathological model for Fragile X syndrome.

  The European journal of neuroscience 20071201

• Thermodynamic characterization of substrate and inhibitor binding to Trypanosoma brucei 6-phosphogluconate dehydrogenase.

  The FEBS journal 20071201

• Cloning and functional analysis of a novel aldo-keto reductase from Aloe arborescens.

  Biological & pharmaceutical bulletin 20071201

• Homocysteine effects on cellular glutathione peroxidase (GPx-1) activity under in vitro conditions.

  Journal of enzyme inhibition and medicinal chemistry 20071201

• 10-formyltetrahydrofolate dehydrogenase requires a 4'-phosphopantetheine prosthetic group for catalysis.

  The Journal of biological chemistry 20071123

• Hydrogen sulfide inhibits activity of three isoforms of recombinant nitric oxide synthase.

  Toxicology 20071120

• Elucidation of a complete kinetic mechanism for a mammalian hydroxysteroid dehydrogenase (HSD) and identification of all enzyme forms on the reaction coordinate: the example of rat liver 3alpha-HSD (AKR1C9).

  The Journal of biological chemistry 20071116

• NAD kinase levels control the NADPH concentration in human cells.

  The Journal of biological chemistry 20071116

• Oral administration of diphenylarsinic acid, a degradation product of chemical warfare agents, induces oxidative and nitrosative stress in cerebellar Purkinje cells.

  Life sciences 20071110

• Tracing changes in protonation: a prerequisite to factorize thermodynamic data of inhibitor binding to aldose reductase.

  Journal of molecular biology 20071109

• Mechanistic studies of Bacillus subtilis QueF, the nitrile oxidoreductase involved in queuosine biosynthesis.

  Biochemistry 20071106

• Laser excitation studies of the product release steps in the catalytic cycle of the light-driven enzyme, protochlorophyllide oxidoreductase.

  The Journal of biological chemistry 20071102

• Identification of disulfide reductases in Campylobacterales: a bioinformatics investigation.

  Antonie van Leeuwenhoek 20071101

• CYP2A13: variable expression and role in human lung microsomal metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

  The Journal of pharmacology and experimental therapeutics 20071101

• Polymorphic variants of CYP2C9: mechanisms involved in reduced catalytic activity.

  Molecular pharmacology 20071101

• CYP201A2, a cytochrome P450 from Rhodopseudomonas palustris, plays a key role in the biodegradation of tributyl phosphate.

  Applied microbiology and biotechnology 20071101

• Cryptosporidium parvum long-chain fatty acid elongase.

  Eukaryotic cell 20071101

• NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine.

  Chemical research in toxicology 20071101

• Isolation and characterization of a benzoylformate decarboxylase and a NAD+/NADP+-dependent benzaldehyde dehydrogenase involved in D-phenylglycine metabolism in Pseudomonas stutzeri ST-201.

  Biochimica et biophysica acta 20071101

• Autofluorescence properties of rat liver under hypermetabolic conditions.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20071101

• [Mechanism of DNA damage and apoptosis induced by anticancer drugs through generation of reactive oxygen species].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20071101

• Biochemical characterization of a flavin adenine dinucleotide-dependent monooxygenase, ornithine hydroxylase from Pseudomonas aeruginosa, suggests a novel reaction mechanism.

  Biochemistry 20071023

• Glutathione traps formaldehyde by formation of a bicyclo[4.4.1]undecane adduct.

  Organic & biomolecular chemistry 20071021

• Crystal structures of shikimate dehydrogenase AroE from Thermus thermophilus HB8 and its cofactor and substrate complexes: insights into the enzymatic mechanism.

  Journal of molecular biology 20071019

• Infrared multiphoton dissociation and electron-induced dissociation as alternative MS/MS strategies for metabolite identification.

  Analytical chemistry 20071015

• Attenuation of insulin secretion by insulin-like growth factor binding protein-1 in pancreatic beta-cells.

  Biochemical and biophysical research communications 20071012

• Cytochrome b5 increases the rate of product formation by cytochrome P450 2B4 and competes with cytochrome P450 reductase for a binding site on cytochrome P450 2B4.

  The Journal of biological chemistry 20071012

• The crystal structure of the bifunctional deaminase/reductase RibD of the riboflavin biosynthetic pathway in Escherichia coli: implications for the reductive mechanism.

  Journal of molecular biology 20071012

• Identification and characterization of the Tuber borchii D-mannitol dehydrogenase which defines a new subfamily within the polyol-specific medium chain dehydrogenases.

  Fungal genetics and biology : FG & B 20071001

• Induction of CYP1A1 and CYP2E1 in rat liver by histamine: binding and kinetic studies.

  Archives of toxicology 20071001

• Study on the biochemical basis of mefloquine resistant Plasmodium falciparum.

  Experimental parasitology 20071001

• Several distinct enzymes catalyze 20alpha-hydroxysteroid dehydrogenase activity in mouse liver and kidney.

  The Journal of steroid biochemistry and molecular biology 20071001

• A novel method using fluorescence microscopy for real-time assessment of ATP release from individual cells.

  American journal of physiology. Cell physiology 20071001

• New concept for a toxicity assay based on multiple indexes from the wave shape of damped metabolic oscillation induced in living yeast cells (part II): application to analytical toxicology.

  Analytical and bioanalytical chemistry 20071001

• New concept for a toxicity assay based on multiple indexes from the wave shape of damped metabolic oscillation induced in living yeast cells (part I): characterization of the phenomenon.

  Analytical and bioanalytical chemistry 20071001

• Steroid 5alpha-reductase activity of Treponema denticola.

  Oral microbiology and immunology 20071001

• Probing the determinants of coenzyme specificity in Peptostreptococcus asaccharolyticus glutamate dehydrogenase by site-directed mutagenesis.

  The FEBS journal 20071001

• Biodegradation of kerosene by Aspergillus ochraceus NCIM-1146.

  Journal of basic microbiology 20071001

• Ciliary neurotrophic factor promotes survival of neonatal rat islets via the BCL-2 anti-apoptotic pathway.

  The Journal of endocrinology 20071001

• Transcriptional regulation of NADP-dependent malate dehydrogenase: comparative genetics and identification of DNA-binding proteins.

  Journal of molecular evolution 20071001

• Thioredoxin-like domains required for glucose regulatory protein 58 mediated reductive activation of mitomycin C leading to DNA cross-linking.

  Molecular cancer therapeutics 20071001

• Ca2+-binding and Ca2+-independent respiratory NADH and NADPH dehydrogenases of Arabidopsis thaliana.

  The Journal of biological chemistry 20070928

• Purification and kinetic properties of glutathione reductase from bovine liver.

  Molecular and cellular biochemistry 20070901

• Characterization of malate dehydrogenase from the hyperthermophilic archaeon Pyrobaculum islandicum.

  Extremophiles : life under extreme conditions 20070901

• Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway.

  Molecular microbiology 20070901

• mu-crystallin, a NADPH-dependent T(3)-binding protein in cytosol.

  Trends in endocrinology and metabolism: TEM 20070901

• Cofactor-specific modulation of 11beta-hydroxysteroid dehydrogenase 1 inhibitor potency.

  Biochimica et biophysica acta 20070901

• 11Beta-hydroxysteroid dehydrogenase enzymes in the testis and male reproductive tract of the boar (Sus scrofa domestica) indicate local roles for glucocorticoids in male reproductive physiology.

  Reproduction (Cambridge, England) 20070901

• Reconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (NAADP)-sensitive Ca2+ release channel from liver lysosomes of rats.

  The Journal of biological chemistry 20070831

• Melatonin attenuates metabolic disorders due to streptozotocin-induced diabetes in rats.

  European journal of pharmacology 20070827

• Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism.

  Biochemistry 20070821

• Modification of substrate specificity in single point mutants of Agrobacterium tumefaciens type II NADH dehydrogenase.

  FEBS letters 20070821

• NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

  The Biochemical journal 20070815

• Neuroglobin and cytoglobin as potential enzyme or substrate.

  Gene 20070815

• New insight into the mechanism of action of and resistance to isoniazid: interaction of Mycobacterium tuberculosis enoyl-ACP reductase with INH-NADP.

  Journal of the American Chemical Society 20070808

• Tps1 regulates the pentose phosphate pathway, nitrogen metabolism and fungal virulence.

  The EMBO journal 20070808

• Mutation of a single residue (K262R) in P450 2B6 leads to loss of mechanism-based inactivation by phencyclidine.

  Drug metabolism and disposition: the biological fate of chemicals 20070801

• Enhanced production of epsilon-caprolactone by overexpression of NADPH-regenerating glucose 6-phosphate dehydrogenase in recombinant Escherichia coli harboring cyclohexanone monooxygenase gene.

  Applied microbiology and biotechnology 20070801

• Preservation of mitochondrial function may contribute to cardioprotective effects of Na+/Ca2+ exchanger inhibitors in ischaemic/reperfused rat hearts.

  British journal of pharmacology 20070801

• Folate salvage in plants: pterin aldehyde reduction is mediated by multiple non-specific aldehyde reductases.

  The Plant journal : for cell and molecular biology 20070801

• Reduction of vanadium(V) to vanadium(IV) by NADPH, and vanadium(IV) to vanadium(III) by cysteine methyl ester in the presence of biologically relevant ligands.

  Biochimica et biophysica acta 20070801

• Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in salt-sensitive hypertension.

  Hypertension (Dallas, Tex. : 1979) 20070801

• Clinical, structural and functional implications of mutations and polymorphisms in human NADPH P450 oxidoreductase.

  Fundamental & clinical pharmacology 20070801

• Enzymatic oxidation of NADP+ to its 4-oxo derivative is a side-reaction displayed only by the adrenodoxin reductase type of ferredoxin-NADP+ reductases.

  The FEBS journal 20070801

• Glutathione S-transferase conjugation of organophosphorus pesticides yields S-phospho-, S-aryl-, and S-alkylglutathione derivatives.

  Chemical research in toxicology 20070801

• 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines.

  Toxicology letters 20070801

• Temporal window of metabolic brain vulnerability to concussions: mitochondrial-related impairment--part I.

  Neurosurgery 20070801

• Purification and characterization of an intracellular NADH: quinone reductase from Trametes versicolor.

  Journal of microbiology (Seoul, Korea) 20070801

• The inhibition kinetics of yeast glutathione reductase by some metal ions.

  Journal of enzyme inhibition and medicinal chemistry 20070801

• NADPH binding to beta-subunit regulates inactivation of voltage-gated K(+) channels.

  Biochemical and biophysical research communications 20070727

• Insights from modeling the 3D structure of NAD(P)H-dependent D-xylose reductase of Pichia stipitis and its binding interactions with NAD and NADP.

  Biochemical and biophysical research communications 20070727

• Electrochemical study of a reconstituted photosynthetic electron-transfer chain.

  Journal of the American Chemical Society 20070725

• Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis.

  The Journal of biological chemistry 20070706

• The relationship of the redox potentials of thioredoxin and thioredoxin reductase from Drosophila melanogaster to the enzymatic mechanism: reduced thioredoxin is the reductant of glutathione in Drosophila.

  Biochemistry 20070703

• 4-hydroxy nimesulide effects on mitochondria and HepG2 cells. A comparison with nimesulide.

  European journal of pharmacology 20070702

• Cisplatin-induced nephrotoxicity is associated with oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria.

  Archives of toxicology 20070701

• Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathway.

  Journal of neurochemistry 20070701

• Nitrite-driven anaerobic ATP synthesis in barley and rice root mitochondria.

  Planta 20070701

• Cofactor regeneration in phototrophic cyanobacteria applied for asymmetric reduction of ketones.

  Applied microbiology and biotechnology 20070701

• Activation of biliverdin-IXalpha reductase by inorganic phosphate and related anions.

  The Biochemical journal 20070701

• Identification of a novel glutathione conjugate of flutamide in incubations with human liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20070701

• Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20070701

• CYP2C9 protein interactions with cytochrome b(5): effects on the coupling of catalysis.

  Drug metabolism and disposition: the biological fate of chemicals 20070701

• Pyrimethamine-resistant dihydrofolate reductase enzymes of Plasmodium falciparum are not enzymatically compromised in vitro.

  Molecular and biochemical parasitology 20070701

• NAD-dependent isocitrate dehydrogenase mutants of Arabidopsis suggest the enzyme is not limiting for nitrogen assimilation.

  Plant physiology 20070701

• Inhibition of isolated Mycobacterium tuberculosis fatty acid synthase I by pyrazinamide analogs.

  Antimicrobial agents and chemotherapy 20070701

• A cytosolic NADP-malic enzyme gene from rice (Oryza sativa L.) confers salt tolerance in transgenic Arabidopsis.

  Biotechnology letters 20070701

• Cerebral vascular dysfunction during hypercholesterolemia.

  Stroke 20070701

• Reduced expression of the NADPH oxidase NOX4 is a hallmark of adipocyte differentiation.

  Biochimica et biophysica acta 20070701

• Degradation kinetics of caffeine and related methylxanthines by induced cells of Pseudomonas sp.

  Current microbiology 20070701

• Novel oxidative metabolites of the mycoestrogen zearalenone in vitro.

  Molecular nutrition & food research 20070701

• High-resolution structures of oxidized and reduced thioredoxin reductase from Helicobacter pylori.

  Acta crystallographica. Section D, Biological crystallography 20070701

• The fate of glucose during the period of decreased metabolism after fluid percussion injury: a 13C NMR study.

  Journal of neurotrauma 20070701

• 2-Methoxy antimycin reveals a unique mechanism for Bcl-x(L) inhibition.

  Molecular cancer therapeutics 20070701

• Identification of radicals formed in the reaction mixtures of rat liver microsomes with ADP, Fe3+ and NADPH using HPLC EPR and HPLC EPR MS.

  Journal of biochemistry 20070701

• Melatonin and N-acetyl serotonin inhibit selectively enzymatic and non-enzymatic lipid peroxidation of rat liver microsomes.

  Prostaglandins, leukotrienes, and essential fatty acids 20070701

• Ethanol production from xylose by recombinant Saccharomyces cerevisiae expressing protein engineered NADP+-dependent xylitol dehydrogenase.

  Journal of biotechnology 20070630

• NAADP mobilizes calcium from the endoplasmic reticular Ca(2+) store in T-lymphocytes.

  The Journal of biological chemistry 20070629

• The structure of human thioredoxin reductase 1 provides insights into C-terminal rearrangements during catalysis.

  Journal of molecular biology 20070629

• Asymmetric reduction of beta-ketonitriles with a recombinant carbonyl reductase and enzymatic transformation to optically pure beta-hydroxy carboxylic acids.

  Organic letters 20070621

• Regulation of LPS stimulated ROS production in peritoneal macrophages from alloxan-induced diabetic rats: involvement of high glucose and PPARgamma.

  Life sciences 20070620

• Renewable dehydrogenase-based interfaces for bioelectronic applications.

  Langmuir : the ACS journal of surfaces and colloids 20070619

• CD95 activation in the liver: ion fluxes and oxidative signaling.

  Archives of biochemistry and biophysics 20070615

• Competitive inhibition of glutamate dehydrogenase reaction.

  FEBS letters 20070612

• PPADS is a reversible competitive antagonist of the NAADP receptor.

  Cell calcium 20070601

• Cytochrome P450 destruction by benzene metabolites 1,4-benzoquinone and 1,4-hydroquinone and the formation of hydroxyl radicals in minipig liver microsomes.

  Toxicology in vitro : an international journal published in association with BIBRA 20070601

• A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity.

  Drug metabolism and disposition: the biological fate of chemicals 20070601

• Metabolism of prazosin in rat, dog, and human liver microsomes and cryopreserved rat and human hepatocytes and characterization of metabolites by liquid chromatography/tandem mass spectrometry.

  Drug metabolism and disposition: the biological fate of chemicals 20070601

• Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.

  Journal of molecular biology 20070601

• Decoding the mannitol enigma in filamentous fungi.

  Trends in microbiology 20070601

• Polymorphism C242T of the gene of the p22phox subunit for nicotinamide adenine dinucleotide phosphate oxidase, and erythrocytic antioxidant enzymes, in patients with tetralogy of Fallot.

  Cardiology in the young 20070601

• Electron paramagnetic resonance analyses of biotransformation reactions with cytochrome P-450 immobilized on mesoporous molecular sieves.

  Biotechnology letters 20070601

• Structure of the Q67H mutant of R67 dihydrofolate reductase-NADP+ complex reveals a novel cofactor binding mode.

  Protein science : a publication of the Protein Society 20070601

• Human and yeast zeta-crystallins bind AU-rich elements in RNA.

  Cellular and molecular life sciences : CMLS 20070601

• Cytosolic NAD(P)H regulation of redox signaling and vascular oxygen sensing.

  Antioxidants & redox signaling 20070601

• New insights into the binding mode of coenzymes: structure of Thermus thermophilus Delta1-pyrroline-5-carboxylate dehydrogenase complexed with NADP+.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20070601

• Structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20070601

• Low glutathione peroxidase in rd1 mouse retina increases oxidative stress and proteases.

  Neuroreport 20070528

• Crystal structure of vestitone reductase from alfalfa (Medicago sativa L.).

  Journal of molecular biology 20070525

• Intermediate release by ADP-L-glycero-D-manno-heptose 6-epimerase.

  Biochemistry 20070522

• NAADP controls cross-talk between distinct Ca2+ stores in the heart.

  The Journal of biological chemistry 20070518

• Crystal structure of grape dihydroflavonol 4-reductase, a key enzyme in flavonoid biosynthesis.

  Journal of molecular biology 20070518

• An enzymatic cycling assay for nicotinic acid adenine dinucleotide phosphate using NAD synthetase.

  Analytical biochemistry 20070515

• Thioredoxin-linked metabolism in Entamoeba histolytica.

  Free radical biology & medicine 20070515

• The external alternative NAD(P)H dehydrogenase NDE3 is localized both in the mitochondria and in the cytoplasm of Neurospora crassa.

  Journal of molecular biology 20070511

• Regulation of ionizing radiation-induced apoptosis by mitochondrial NADP+-dependent isocitrate dehydrogenase.

  The Journal of biological chemistry 20070504

• Vitamin E reduces glomerulosclerosis, restores renal neuronal NOS, and suppresses oxidative stress in the 5/6 nephrectomized rat.

  American journal of physiology. Renal physiology 20070501

• Expression of the Escherichia coli pntAB genes encoding a membrane-bound transhydrogenase in Corynebacterium glutamicum improves L-lysine formation.

  Applied microbiology and biotechnology 20070501

• Oxidation of vinyl carbamate and formation of 1,N6-ethenodeoxyadenosine in murine lung.

  Drug metabolism and disposition: the biological fate of chemicals 20070501

• Inhibition of Rho-kinase attenuates nephrosclerosis and improves survival in salt-loaded spontaneously hypertensive stroke-prone rats.

  Journal of hypertension 20070501

• 11beta-Hydroxysteroid dehydrogenase expression and activities in bovine granulosa cells and corpora lutea implicate corticosteroids in bovine ovarian physiology.

  The Journal of endocrinology 20070501

• Ferulic acid restores endothelium-dependent vasodilation in aortas of spontaneously hypertensive rats.

  American journal of hypertension 20070501

• The positive effect of the decreased NADPH-preferring activity of xylose reductase from Pichia stipitis on ethanol production using xylose-fermenting recombinant Saccharomyces cerevisiae.

  Bioscience, biotechnology, and biochemistry 20070501

• The laterodorsal tegmentum contributes to behavioral sensitization to amphetamine.

  Neuroscience 20070425

• Expression of a novel alternatively spliced variant of NADP(H)-dependent retinol dehydrogenase/reductase with deletion of exon 3 in cervical squamous carcinoma.

  International journal of cancer 20070415

• Fertilization causes a single Ca2+ increase that fully depends on Ca2+ influx in oocytes of limpets (Phylum Mollusca, Class Gastropoda).

  Developmental biology 20070415

• A chromone analog inhibits TNF-alpha induced expression of cell adhesion molecules on human endothelial cells via blocking NF-kappaB activation.

  Bioorganic & medicinal chemistry 20070415

• Crystal structure of N-acetyl-gamma-glutamyl-phosphate reductase from Mycobacterium tuberculosis in complex with NADP(+).

  Journal of molecular biology 20070413

• A NADPH substitute for selective photo-initiation of reductive bioprocesses via two-photon induced electron transfer.

  Chemical communications (Cambridge, England) 20070407

• The overexpression of NADPH-producing enzymes counters the oxidative stress evoked by gallium, an iron mimetic.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20070401

• Regulation of 5-hydroxyeicosanoid dehydrogenase activity in monocytic cells.

  The Biochemical journal 20070401

• Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose.

  The Biochemical journal 20070401

• Resveratrol attenuates oxLDL-stimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damages.

  Journal of applied physiology (Bethesda, Md. : 1985) 20070401

• Elevated glucose concentrations promote receptor-independent activation of adherent human neutrophils: an experimental and computational approach.

  Biophysical journal 20070401

• Visible spectra of type II cytochrome P450-drug complexes: evidence that 'incomplete' heme coordination is common.

  Drug metabolism and disposition: the biological fate of chemicals 20070401

• The inactivation of cytochrome P450 3A5 by 17alpha-ethynylestradiol is cytochrome b5-dependent: metabolic activation of the ethynyl moiety leads to the formation of glutathione conjugates, a heme adduct, and covalent binding to the apoprotein.

  The Journal of pharmacology and experimental therapeutics 20070401

• Differential effects of organic nitrates on endothelial progenitor cells are determined by oxidative stress.

  Arteriosclerosis, thrombosis, and vascular biology 20070401

• Potent inhibition of store-operated Ca2+ influx and superoxide production in HL60 cells and polymorphonuclear neutrophils by the pyrazole derivative BTP2.

  Journal of leukocyte biology 20070401

• micro-Crystallin as an intracellular 3,5,3'-triiodothyronine holder in vivo.

  Molecular endocrinology (Baltimore, Md.) 20070401

• Characterization of in vivo tissue redox status, oxygenation, and formation of reactive oxygen species in postischemic myocardium.

  Antioxidants & redox signaling 20070401

• A plate reader method for the measurement of NAD, NADP, glutathione, and ascorbate in tissue extracts: Application to redox profiling during Arabidopsis rosette development.

  Analytical biochemistry 20070401

• Structural observations of time dependent oscillatory behavior of CuIICl2 solutions measured via extended X-ray absorption fine structure.

  Journal of inorganic biochemistry 20070401

• Knock-out of the chloroplast-encoded PSI-J subunit of photosystem I in Nicotiana tabacum.

  The FEBS journal 20070401

• Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer.

  British journal of pharmacology 20070401

• Asymmetric bioreduction of activated C=C bonds using enoate reductases from the old yellow enzyme family.

  Current opinion in chemical biology 20070401

• Source-dependent variation in hydroxyl radical production by airborne particulate matter.

  Environmental science & technology 20070401

• Effect of anabolic steroid nandrolone decanoate on the properties of certain enzymes in the heart, liver, and muscle of rats, and their effect on rats' cardiac electrophysiology.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20070401

• The endogenous neurotransmitter, serotonin, modifies neuronal nitric oxide synthase activities.

  Free radical research 20070401

• Evidence for an additional disulfide reduction pathway in Escherichia coli.

  Journal of bioscience and bioengineering 20070401

• A two-base mechanism for Escherichia coli ADP-L-glycero-D-manno-heptose 6-epimerase.

  Biochemistry 20070327

• Ferredoxin-NADP+ reductase from Plasmodium falciparum undergoes NADP+-dependent dimerization and inactivation: functional and crystallographic analysis.

  Journal of molecular biology 20070323

• The influence of diluted seawater and ripening stage on the content of antioxidants in fruits of different tomato genotypes.

  Journal of agricultural and food chemistry 20070321

• Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.

  Biochemistry 20070320

• Structures of the dI2dIII1 complex of proton-translocating transhydrogenase with bound, inactive analogues of NADH and NADPH reveal active site geometries.

  Biochemistry 20070320

• Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase.

  The Journal of biological chemistry 20070316

• Crystal structure of Escherichia coli ketopantoate reductase in a ternary complex with NADP+ and pantoate bound: substrate recognition, conformational change, and cooperativity.

  The Journal of biological chemistry 20070316

• An in vitro study on metabolism of 17beta-boldenone and boldione using cattle liver and kidney subcellular fractions.

  Analytica chimica acta 20070314

• Identification of the last unknown genes in the fermentation pathway of lysine.

  The Journal of biological chemistry 20070309

• Cooperativity in cytochrome P450 3A4: linkages in substrate binding, spin state, uncoupling, and product formation.

  The Journal of biological chemistry 20070309

• Cytochrome P450--redox partner fusion enzymes.

  Biochimica et biophysica acta 20070301

• Salinity-induced decrease in NADPH oxidase activity in the maize leaf blade elongation zone.

  Journal of plant physiology 20070301

• NAADP induces pH changes in the lumen of acidic Ca2+ stores.

  The Biochemical journal 20070301

• Co-expression of P450 BM3 and glucose dehydrogenase by recombinant Escherichia coli and its application in an NADPH-dependent indigo production system.

  Journal of industrial microbiology & biotechnology 20070301

• Pharmacological and physiological stimuli do not promote Ca(2+)-sensitive K+ channel activity in isolated heart mitochondria.

  Cardiovascular research 20070301

• Mechanism of flavin reduction in the alkanesulfonate monooxygenase system.

  Biochimica et biophysica acta 20070301

• Airway epithelial cells synthesize the lipid mediator 5-oxo-ETE in response to oxidative stress.

  Free radical biology & medicine 20070301

• The power to reduce: pyridine nucleotides--small molecules with a multitude of functions.

  The Biochemical journal 20070301

• Biochemical characterization of TASSELSEED 2, an essential plant short-chain dehydrogenase/reductase with broad spectrum activities.

  The FEBS journal 20070301

• Synechocystis DrgA protein functioning as nitroreductase and ferric reductase is capable of catalyzing the Fenton reaction.

  The FEBS journal 20070301

• Lot6p from Saccharomyces cerevisiae is a FMN-dependent reductase with a potential role in quinone detoxification.

  The FEBS journal 20070301

• Structure of archaeal glyoxylate reductase from Pyrococcus horikoshii OT3 complexed with nicotinamide adenine dinucleotide phosphate.

  Acta crystallographica. Section D, Biological crystallography 20070301

• Nicotinamidase participates in the salvage pathway of NAD biosynthesis in Arabidopsis.

  The Plant journal : for cell and molecular biology 20070301

• Effects of oxygen and photosynthesis carbon cycle reactions on kinetics of P700 redox transients in cyanobacterium Arthrospira platensis cells.

  Biochemistry. Biokhimiia 20070301

• Cores and pH-dependent dynamics of ferredoxin-NADP+ reductase revealed by hydrogen/deuterium exchange.

  The Journal of biological chemistry 20070223

• Depurinating acylfulvene-DNA adducts: characterizing cellular chemical reactions of a selective antitumor agent.

  Journal of the American Chemical Society 20070221

• Synchronous photoinitiation of endothelial NO synthase activity by a nanotrigger targeted at its NADPH site.

  Journal of the American Chemical Society 20070221

• Mechanisms involved in the protection of UV-induced protein inactivation by the corneal crystallin ALDH3A1.

  The Journal of biological chemistry 20070216

• Crystal structure of lactaldehyde dehydrogenase from Escherichia coli and inferences regarding substrate and cofactor specificity.

  Journal of molecular biology 20070216

• A generally applicable method for assessing the electrophilicity and reactivity of diverse nitrile-containing compounds.

  Bioorganic & medicinal chemistry letters 20070215

• Gp91phox-containing NAD(P)H oxidase increases superoxide formation by doxorubicin and NADPH.

  Free radical biology & medicine 20070215

• Lipid lowering effect of S-methyl cysteine sulfoxide from Allium cepa Linn in high cholesterol diet fed rats.

  Journal of ethnopharmacology 20070212

• Regulation of common carotid arterial blood flow by nitrergic neurons in the medulla of cats.

  European journal of pharmacology 20070205

• Functional consequences of mitochondrial proteome heterogeneity.

  American journal of physiology. Cell physiology 20070201

• Cytokine expression and AIF-1-mediated activation of Rac2 in vascular smooth muscle cells: a role for Rac2 in VSMC activation.

  American journal of physiology. Cell physiology 20070201

• Bioconversion of ethyl 4-chloro-3-oxobutanoate by permeabilized fresh brewer's yeast cells in the presence of allyl bromide.

  Journal of industrial microbiology & biotechnology 20070201

• Generation of superoxide anion by equine spermatozoa as detected by dihydroethidium.

  Theriogenology 20070201

• Visual cycle and its metabolic support in gecko photoreceptors.

  Vision research 20070201

• At5g50600 encodes a member of the short-chain dehydrogenase reductase superfamily with 11beta- and 17beta-hydroxysteroid dehydrogenase activities associated with Arabidopsis thaliana seed oil bodies.

  Biochimie 20070201

• Metabolism of MK-0524, a prostaglandin D2 receptor 1 antagonist, in microsomes and hepatocytes from preclinical species and humans.

  Drug metabolism and disposition: the biological fate of chemicals 20070201

• Regulation of redox metabolism in the mouse oocyte and embryo.

  Development (Cambridge, England) 20070201

• Cofactors, redox state, and directional preferences of hydroxysteroid dehydrogenases.

  Molecular and cellular endocrinology 20070201

• Regulation of calcium signalling by adenine-based second messengers.

  Biochemical Society transactions 20070201

• Crystal structure of human micro-crystallin complexed with NADPH.

  Protein science : a publication of the Protein Society 20070201

• pH-tuneable binding of 2'-phospho-ADP-ribose to ketopantoate reductase: a structural and calorimetric study.

  Acta crystallographica. Section D, Biological crystallography 20070201

• Characteristics of alpha-glycerophosphate-evoked H2O2 generation in brain mitochondria.

  Journal of neurochemistry 20070201

• Neuroprotective effects of TJ-23 (Tokishakuyakusan) on adult rat motoneurons following peripheral facial nerve axotomy.

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20070201

• Age-dependent retinal capillary pericyte degeneration in galactose-fed dogs.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20070201

• Nonenzymatic reduction of thymoquinone in physiological conditions.

  Free radical research 20070201

• Hepatocyte susceptibility to glyoxal is dependent on cell thiamin content.

  Chemico-biological interactions 20070130

• Synthesis of the isonicotinoylnicotinamide scaffolds of the naturally occurring isoniazid-NAD(P) adducts.

  The Journal of organic chemistry 20070119

• A rapid assay for dihydropteroate synthase activity suitable for identification of inhibitors.

  Analytical biochemistry 20070115

• Metabolite transport across the peroxisomal membrane.

  The Biochemical journal 20070115

• Kinetic and chemical mechanisms of shikimate dehydrogenase from Mycobacterium tuberculosis.

  Archives of biochemistry and biophysics 20070115

• HIV-1 trans activator of transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with dysregulation of complex IV and nicotinamide adenine dinucleotide homeostasis in cortical neurons.

  Journal of immunology (Baltimore, Md. : 1950) 20070115

• Single and cell population respiratory oscillations in yeast: a 2-photon scanning laser microscopy study.

  FEBS letters 20070109

• Bioreductive activation of mitoxantrone by NADPH cytochrome P450 reductase. Implications for increasing its ability to inhibit the growth of sensitive and multidrug resistant leukaemia HL60 cells.

  Cancer letters 20070108

• Cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion.

  The Journal of biological chemistry 20070105

• Identification of 2,3-epoxymethacrylic acid as an intermediate in the metabolism of dental materials in human liver microsomes.

  Dental materials : official publication of the Academy of Dental Materials 20070101

• Decreases in taurine levels induced by beta-alanine treatment did not affect the susceptibility of tissues to lipid peroxidation.

  Amino acids 20070101

• NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells.

  American journal of physiology. Cell physiology 20070101

• The NADPH- and iron-dependent lipid peroxidation in human placental microsomes.

  Molecular and cellular biochemistry 20070101

• NADPH recycling systems in oxidative stressed pea nodules: a key role for the NADP+ -dependent isocitrate dehydrogenase.

  Planta 20070101

• Peritubular capillary dysfunction and renal tubular epithelial cell stress following lipopolysaccharide administration in mice.

  American journal of physiology. Renal physiology 20070101

• High-level expression of recombinant glucose dehydrogenase and its application in NADPH regeneration.

  Journal of industrial microbiology & biotechnology 20070101

• Efficient regeneration of NADPH using an engineered phosphite dehydrogenase.

  Biotechnology and bioengineering 20070101

• Cytosolic NADPH metabolism in penicillin-G producing and non-producing chemostat cultures of Penicillium chrysogenum.

  Metabolic engineering 20070101

• Glucose-6-phosphate-dehydrogenase deficiency is a possible predisposer to Th2-dominant disorders.

  Medical hypotheses 20070101

• An evaluation of the cytochrome p450 inhibition potential of lisdexamfetamine in human liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20070101

• Mitochondrial isocitrate dehydrogenase protects human neuroblastoma SH-SY5Y cells against oxidative stress.

  Journal of neuroscience research 20070101

• Functional identification of a protein inhibitor of neuronal nitric oxide synthase of Taenia solium metacestode.

  Molecular and biochemical parasitology 20070101

• Langhans giant cells from M. tuberculosis-induced human granulomas cannot mediate mycobacterial uptake.

  The Journal of pathology 20070101

• Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3beta activation.

  Cardiovascular research 20070101

• Oxalomalate regulates ionizing radiation-induced apoptosis in mice.

  Free radical biology & medicine 20070101

• Changes in disulfide bond content of proteins in a yeast strain lacking major sources of NADPH.

  Free radical biology & medicine 20070101

• Amyloid-beta peptide affects the oxygen dependence of erythrocyte metabolism: a role for caspase 3.

  The international journal of biochemistry & cell biology 20070101

• Unique properties of NADP-thioredoxin reductase C in legumes.

  Journal of experimental botany 20070101

• Anoxia-induced changes in pyridine nucleotide redox state in cortical neurons and astrocytes.

  Neurochemical research 20070101

• Vulnerability of dopaminergic amacrine cells and optic nerve myelination to prenatal endotoxin exposure.

  Investigative ophthalmology & visual science 20070101

• [Features of the toxic action of 2,4,6-trinitrotoluene on Escherichia coli K12].

  Prikladnaia biokhimiia i mikrobiologiia 20070101

• A light-driven stereoselective biocatalytic oxidation.

  Angewandte Chemie (International ed. in English) 20070101

• Arthritis suppression by NADPH activation operates through an interferon-beta pathway.

  BMC biology 20070101

• X-linked chronic granulomatous disease (CGD) caused by an intra-exonic splice mutation (CYBB exon 3, c.262G->A) is mimicking juvenile sarcoidosis.

  Clinical and experimental rheumatology 20070101

• Changes in photosynthetic metabolism induced by tobamovirus infection in Nicotiana benthamiana studied in vivo by thermoluminescence.

  The New phytologist 20070101

• [A rapid method to evaluate potential vasodilatory activity of organic nitrates].

  Prikladnaia biokhimiia i mikrobiologiia 20070101

• Glucose-6-phosphate dehydrogenase--from oxidative stress to cellular functions and degenerative diseases.

  Redox report : communications in free radical research 20070101

• Metabolic flux elucidation for large-scale models using 13C labeled isotopes.

  Metabolic engineering 20070101

• Three-dimensional modeling of glucose-6-phosphate dehydrogenase-deficient variants from German ancestry.

  PloS one 20070101

• [Thioctic acid action on glutathione-dependent antioxidant system functioning at toxic hepatitis of rats].

  Biomeditsinskaia khimiia 20070101

• Bayesian refinement of protein functional site matching.

  BMC bioinformatics 20070101

• Overproduction and characterization of two distinct aldehyde-oxidizing enzymes from Gluconobacter oxydans 621H.

  Journal of molecular microbiology and biotechnology 20070101

• Functional activity of the mouse flavin-containing monooxygenase forms 1, 3, and 5.

  Journal of biochemical and molecular toxicology 20070101

• Molecular characterization of a novel intracellular ADP-ribosyl cyclase.

  PloS one 20070101

• Analysis of the interactions of cytochrome b5 with flavocytochrome P450 BM3 and its domains.

  Drug metabolism reviews 20070101

• [Metabolic changes of lymphocytes and neoplastic cells in mice with Ehrlich ascites carcinoma during tumor growth].

  Izvestiia Akademii nauk. Seriia biologicheskaia 20070101

• [Effects of light-induced changes in pH of stroma and lumen on the kinetics of electron transport in chloroplasts. A mathematical model].

  Biofizika 20070101

• Structure and reaction mechanism of basil eugenol synthase.

  PloS one 20070101

• Integrated, electrically contacted NAD(P)+-dependent enzyme-carbon nanotube electrodes for biosensors and biofuel cell applications.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

• Crystal structures of Leptospira interrogans FAD-containing ferredoxin-NADP+ reductase and its complex with NADP+.

  BMC structural biology 20070101

• [NADP pool state and activity of NADP-dependent dehydrogenases in the heart tissue of adult and old rats during immobilization stress].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101

• Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress.

  Journal of biology 20070101

• Isolation and functional analysis of mitochondria from the nematode Caenorhabditis elegans.

  Methods in molecular biology (Clifton, N.J.) 20070101

• [Antiedematous effect of diphenyliodinium salts on experimental toxic lung edema].

  Eksperimental'naia i klinicheskaia farmakologiia 20070101

• [Studies of interaction of intracellular signalling and metabolic pathways under inhibition of mitochondrial aconitase with fluoroacetate].

  Tsitologiia 20070101

• Reversed Na+/Ca2+ exchange contributes to Ca2+ influx and respiratory burst in microglia.

  Channels (Austin, Tex.) 20070101

• Bile acids induce Ca2+ release from both the endoplasmic reticulum and acidic intracellular calcium stores through activation of inositol trisphosphate receptors and ryanodine receptors.

  The Journal of biological chemistry 20061229

• Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells.

  The Journal of biological chemistry 20061229

• Genotoxic potential of medroxyprogesterone acetate in cultured human peripheral blood lymphocytes.

  Life sciences 20061223

• Conformational heterogeneity and low-frequency vibrational modes of proteins.

  Physical chemistry chemical physics : PCCP 20061221

• Invariant Thr244 is essential for the efficient acylation step of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans.

  The Biochemical journal 20061215

• Crystal structure of 3-hydroxybenzoate hydroxylase from Comamonas testosteroni has a large tunnel for substrate and oxygen access to the active site.

  Journal of molecular biology 20061215

• Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.

  Journal of molecular biology 20061208

• Molecular cloning and characterization of the alcohol dehydrogenase ADH1 gene of Candida utilis ATCC 9950.

  Journal of industrial microbiology & biotechnology 20061201

• Enhanced oxidative stress in kidneys of salt-sensitive hypertension: role of sensory nerves.

  American journal of physiology. Heart and circulatory physiology 20061201

• Schisandrin B induced antioxidant response is partly mediated by cytochrome P-4502E1 catalyzed reaction in mouse liver.

  Molecular and cellular biochemistry 20061201

• The 2'-phosphate of NADP is responsible for proper orientation of the nicotinamide ring in the oxidative decarboxylation reaction catalyzed by sheep liver 6-phosphogluconate dehydrogenase.

  The Journal of biological chemistry 20061201

• New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions.

  Proteins 20061201

• Peroxisomal membrane permeability and solute transfer.

  Biochimica et biophysica acta 20061201

• Tight binding of NADPH to the 39-kDa subunit of complex I is not required for catalytic activity but stabilizes the multiprotein complex.

  Biochimica et biophysica acta 20061201

• Screening of drug metabolism by CE.

  Electrophoresis 20061201

• Stereoselective reduction of carbonyl compounds using the cell-free extract of the earthworm, Lumbricus rubellus, as a novel source of biocatalyst.

  Bioscience, biotechnology, and biochemistry 20061201

• NADP(+)-dependent D-arabinose dehydrogenase shows a limited contribution to erythroascorbic acid biosynthesis and oxidative stress resistance in Saccharomyces cerevisiae.

  Bioscience, biotechnology, and biochemistry 20061201

• KlADH3, a gene encoding a mitochondrial alcohol dehydrogenase, affects respiratory metabolism and cytochrome content in Kluyveromyces lactis.

  FEMS yeast research 20061201

• Cytochromes P450 reconstituted with NADPH: P450 reductase mimic the activating and detoxicating metabolism of the anticancer drug ellipticine in microsomes.

  Neuro endocrinology letters 20061201

• Nuclear factor-E2-related factor 2 expression in liver is critical for induction of NAD(P)H:quinone oxidoreductase 1 during cholestasis.

  Cell stress & chaperones 20061201

• Combination of NADPH and copper ions generates proteinase K-resistant aggregates from recombinant prion protein.

  The Journal of biological chemistry 20061117

• Identification of a novel NADH-specific aldo-keto reductase using sequence and structural homologies.

  The Biochemical journal 20061115

• Role of redox factor-1 in hyperhomocysteinemia-accelerated atherosclerosis.

  Free radical biology & medicine 20061115

• The role of a conserved serine residue within hydrogen bonding distance of FAD in redox properties and the modulation of catalysis by Ca2+/calmodulin of constitutive nitric-oxide synthases.

  The Journal of biological chemistry 20061110

• Identification of acid-base catalytic residues of high-Mr thioredoxin reductase from Plasmodium falciparum.

  The Journal of biological chemistry 20061103

• NAD(P)H fluorescence transients after synaptic activity in brain slices: predominant role of mitochondrial function.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20061101

• Synthesis of substituted phenyl diaziridines and characterization as mechanism-based inactivators of human cytochrome P450 2B6.

  Drug metabolism and disposition: the biological fate of chemicals 20061101

• Regulation of insulin secretion and proinsulin biosynthesis by succinate.

  Endocrinology 20061101

• Reactive oxygen species and nuclear factor-kappa B pathway mediate high glucose-induced Pax-2 gene expression in mouse embryonic mesenchymal epithelial cells and kidney explants.

  Kidney international 20061101

• NAADP, a new intracellular messenger that mobilizes Ca2+ from acidic stores.

  Biochemical Society transactions 20061101

• Redox signalling involving NADPH oxidase-derived reactive oxygen species.

  Biochemical Society transactions 20061101

• Alpha-secondary isotope effects as probes of 'tunneling-ready' configurations in enzymatic H-tunneling: insight from environmentally coupled tunneling models.

  Journal of the American Chemical Society 20061101

• Crystallization and structural analysis of GADPH from Spinacia oleracea in a new form.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20061101

• Purification and properties of NADP-dependent shikimate dehydrogenase from Gluconobacter oxydans IFO 3244 and its application to enzymatic shikimate production.

  Bioscience, biotechnology, and biochemistry 20061101

• The metabolic significance of octulose phosphates in the photosynthetic carbon reduction cycle in spinach.

  Photosynthesis research 20061101

• Multiple steps determine the overall rate of the reduction of 5alpha-dihydrotestosterone catalyzed by human type 3 3alpha-hydroxysteroid dehydrogenase: implications for the elimination of androgens.

  Biochemistry 20061031

• Thioredoxin-h1 reduces and reactivates the oxidized cytosolic malate dehydrogenase dimer in higher plants.

  The Journal of biological chemistry 20061027

• Direct demonstration of an adaptive constraint.

  Science (New York, N.Y.) 20061020

• Role of Asp1393 in catalysis, flavin reduction, NADP(H) binding, FAD thermodynamics, and regulation of the nNOS flavoprotein.

  Biochemistry 20061017

• Defective carbohydrate metabolism in mice homozygous for the tubby mutation.

  Physiological genomics 20061011

• Generation of specific Ca(2+) signals from Ca(2+) stores and endocytosis by differential coupling to messengers.

  Current biology : CB 20061010

• Reactive oxygen species, Ca2+ signaling and mitochondrial NAD(P)H level in adrenal glomerulosa cells.

  Cell calcium 20061001

• Protection by 6-aminonicotinamide against oxidative stress in cardiac cells.

  Pharmacological research 20061001

• Variation of 1-pyrenebutyric acid fluorescence lifetime in single living cells treated with molecules increasing or decreasing reactive oxygen species levels.

  Analytical biochemistry 20061001

• A novel NADP+-dependent L-1-amino-2-propanol dehydrogenase from Rhodococcus erythropolis MAK154: a promising enzyme for the production of double chiral aminoalcohols.

  Letters in applied microbiology 20061001

• Isoprenoid biosynthesis in plants - 2C-methyl-D-erythritol-4-phosphate synthase (IspC protein) of Arabidopsis thaliana.

  The FEBS journal 20061001

• Crystallization and preliminary X-ray crystallographic studies of pig heart carbonyl reductase.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20061001

• Metabolism of furans in vitro: ipomeanine and 4-ipomeanol.

  Chemical research in toxicology 20061001

• Acidic residues at the active sites of CD38 and ADP-ribosyl cyclase determine nicotinic acid adenine dinucleotide phosphate (NAADP) synthesis and hydrolysis activities.

  The Journal of biological chemistry 20060929

• Nitrative inactivation of thioredoxin-1 and its role in postischemic myocardial apoptosis.

  Circulation 20060926

• Structure of coenzyme A-disulfide reductase from Staphylococcus aureus at 1.54 A resolution.

  Biochemistry 20060926

• Biosynthesis of fosfomycin, re-examination and re-confirmation of a unique Fe(II)- and NAD(P)H-dependent epoxidation reaction.

  Biochemistry 20060926

• Overstimulation of PrPC signaling pathways by prion peptide 106-126 causes oxidative injury of bioaminergic neuronal cells.

  The Journal of biological chemistry 20060922

• The C-type Arabidopsis thioredoxin reductase ANTR-C acts as an electron donor to 2-Cys peroxiredoxins in chloroplasts.

  Biochemical and biophysical research communications 20060922

• Pharmacological characterization of NAADP-induced Ca2+ signals in starfish oocytes.

  Biochemical and biophysical research communications 20060922

• Isolation and structural elucidation of tiamulin metabolites formed in liver microsomes of pigs.

  Journal of pharmaceutical and biomedical analysis 20060918

• Biosynthesis of acaterin: mechanism of the reaction catalyzed by dehydroacaterin reductase.

  Bioorganic & medicinal chemistry 20060915

• Glucose modulates [Ca2+]i oscillations in pancreatic islets via ionic and glycolytic mechanisms.

  Biophysical journal 20060915

• The first catalytic step of the light-driven enzyme protochlorophyllide oxidoreductase proceeds via a charge transfer complex.

  The Journal of biological chemistry 20060915

• Modulation of calcium signalling by the actin-binding protein cofilin.

  Biochemical and biophysical research communications 20060915

• The dynamic energy landscape of dihydrofolate reductase catalysis.

  Science (New York, N.Y.) 20060915

• Coimmobilization of a redox enzyme and a cofactor regeneration system.

  Chemical communications (Cambridge, England) 20060914

• A transverse tubule NADPH oxidase activity stimulates calcium release from isolated triads via ryanodine receptor type 1 S -glutathionylation.

  The Journal of biological chemistry 20060908

• Cycling of NADPH by glucose 6-phosphate dehydrogenase optimizes the spectrophotometric assay of nitric oxide synthase activity in cell lysates.

  Nitric oxide : biology and chemistry 20060901

• Sublethal concentrations of diverse gold compounds inhibit mammalian cytosolic thioredoxin reductase (TrxR1).

  Toxicology in vitro : an international journal published in association with BIBRA 20060901

• Amino acid residues that determine functional specificity of NADP- and NAD-dependent isocitrate and isopropylmalate dehydrogenases.

  Proteins 20060901

• Fingerprinting DHFR in single-molecule AFM studies.

  Biophysical journal 20060901

• Mitochondrial NADP+-dependent isocitrate dehydrogenase protects cadmium-induced apoptosis.

  Molecular pharmacology 20060901

• Reevaluation of the Griess reaction: how much of a problem is interference by nicotinamide nucleotides?

  Analytical biochemistry 20060901

• Chiral inversion of RS-8359: a selective and reversible MAO-A inhibitor via oxido-reduction of keto-alcohol.

  Chirality 20060901

• Transmembrane topology of FRO2, a ferric chelate reductase from Arabidopsis thaliana.

  Plant molecular biology 20060901

• NADK3, a novel cytoplasmic source of NADPH, is required under conditions of oxidative stress and modulates abscisic acid responses in Arabidopsis.

  The Plant journal : for cell and molecular biology 20060901

• Functional and structural characterization of a thiol peroxidase from Mycobacterium tuberculosis.

  Journal of molecular biology 20060901

• Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina.

  The FEBS journal 20060901

• Alteration of coenzyme specificity of lactate dehydrogenase from Thermus thermophilus by introducing the loop region of NADP(H)-dependent malate dehydrogenase.

  Bioscience, biotechnology, and biochemistry 20060901

• Detection of NADPH-diaphorase activity in Paramecium primaurelia.

  European journal of protistology 20060901

• Alpha-2 adrenergic regulation of pedunculopontine nucleus neurons during development.

  Neuroscience 20060825

• Structural basis for the alteration of coenzyme specificity in a malate dehydrogenase mutant.

  Biochemical and biophysical research communications 20060825

• Induction of ROS formation, poly(ADP-ribose) polymerase-1 activation, and cell death by PCB126 and PCB153 in human T47D and MDA-MB-231 breast cancer cells.

  Chemico-biological interactions 20060825

• Crystal structure of NADP(H)-dependent 1,5-anhydro-D-fructose reductase from Sinorhizobium morelense at 2.2 A resolution: construction of a NADH-accepting mutant and its application in rare sugar synthesis.

  Biochemistry 20060822

• Determinants of the dual cofactor specificity and substrate cooperativity of the human mitochondrial NAD(P)+-dependent malic enzyme: functional roles of glutamine 362.

  The Journal of biological chemistry 20060811

• Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion.

  The Journal of biological chemistry 20060804

• Pollutant particles enhanced H2O2 production from NAD(P)H oxidase and mitochondria in human pulmonary artery endothelial cells.

  American journal of physiology. Cell physiology 20060801

• Reduction in oxidative stress and cell death explains hypothyroidism induced neuroprotection subsequent to ischemia/reperfusion insult.

  Experimental neurology 20060801

• Investigation of the role of a conserved glycine motif in the Saccharomyces cerevisiae xylose reductase.

  Current microbiology 20060801

• Interferon-gamma enhances superoxide production in human mesangial cells via the JAK-STAT pathway.

  Kidney international 20060801

• Glucose-6-phosphate dehydrogenase-derived NADPH fuels superoxide production in the failing heart.

  Journal of molecular and cellular cardiology 20060801

• Structure of apo-glyceraldehyde-3-phosphate dehydrogenase from Synechococcus PCC7942.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060801

• Effects of soyasaponins on lipid peroxidation through the secretion of thyroid hormones.

  Biological & pharmaceutical bulletin 20060801

• Increased TCA cycle activity and reduced oxygen consumption during cytochrome P450-dependent biotransformation in fission yeast.

  Yeast (Chichester, England) 20060801

• Characterization of an Arabidopsis thaliana mutant lacking a cytosolic non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase.

  Plant molecular biology 20060801

• Functional properties of two mutants of human glucose 6-phosphate dehydrogenase, R393G and R393H, corresponding to the clinical variants G6PD Wisconsin and Nashville.

  Biochimica et biophysica acta 20060801

• Occurrence of thioredoxin reductase in Deinococcus species, the UV resistant bacteria.

  Journal of microbiology (Seoul, Korea) 20060801

• Enhanced oxidation of NAD(P)H by oxidants in the presence of dehydrogenases but no evidence for a superoxide-propagated chain oxidation of the bound coenzymes.

  Free radical research 20060801

• Role of the His57-Glu214 ionic couple located in the active site of Mycobacterium tuberculosis FprA.

  Biochemistry 20060725

• Chavicol formation in sweet basil (Ocimum basilicum): cleavage of an esterified C9 hydroxyl group with NAD(P)H-dependent reduction.

  Organic & biomolecular chemistry 20060721

• Enhancement of DMNQ-induced hepatocyte toxicity by cytochrome P450 inhibition.

  Toxicology and applied pharmacology 20060715

• Preparation, characterization, and substrate metabolism of gold-immobilized cytochrome P450 2C9.

  Journal of the American Chemical Society 20060705

• Occurrence of pharmaceutical products in a municipal effluent and toxicity to rainbow trout (Oncorhynchus mykiss) hepatocytes.

  Ecotoxicology and environmental safety 20060701

• Production of NAADP and its role in Ca2+ mobilization associated with lysosomes in coronary arterial myocytes.

  American journal of physiology. Heart and circulatory physiology 20060701

• Structure of a glutathione conjugate bound to the active site of aldose reductase.

  Proteins 20060701

• The crystal structure of a hyperthermostable subfamily II isocitrate dehydrogenase from Thermotoga maritima.

  The FEBS journal 20060701

• Cathepsin B is a differentiation-resistant target for nitroxyl (HNO) in THP-1 monocyte/macrophages.

  Free radical biology & medicine 20060701

• Mitochondria from the left heart ventricles of both normotensive and spontaneously hypertensive rats oxidize externally added NADH mostly via a novel malate/oxaloacetate shuttle as reconstructed in vitro.

  International journal of molecular medicine 20060701

• nDsbD: a redox interaction hub in the Escherichia coli periplasm.

  Cellular and molecular life sciences : CMLS 20060701

• NADPH oxidase in the liver: defensive, offensive, or fibrogenic?

  Gastroenterology 20060701

• Expression and characterization of the genes encoding azoreductases from Bacillus subtilis and Geobacillus stearothermophilus.

  Bioscience, biotechnology, and biochemistry 20060701

• Pioglitazone is metabolised by CYP2C8 and CYP3A4 in vitro: potential for interactions with CYP2C8 inhibitors.

  Basic & clinical pharmacology & toxicology 20060701

• [The effect of NAD kinase homologues on the beta-oxidation of unsaturated fatty acids with the double bond at an even position in Saccharomyces cerevisiae].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20060701

• Two highly divergent alcohol dehydrogenases of melon exhibit fruit ripening-specific expression and distinct biochemical characteristics.

  Plant molecular biology 20060701

• [Fluorescence spectral characteristics of human blood and its endogenous fluorophores].

  Guang pu xue yu guang pu fen xi = Guang pu 20060701

• The dehydrogenase-mediated recycling of NADPH is a key antioxidant system against salt-induced oxidative stress in olive plants.

  Plant, cell & environment 20060701

• NAADP+ synthesis from cADPRP and nicotinic acid by ADP-ribosyl cyclases.

  Biochemical and biophysical research communications 20060630

• NADP+ expels both the co-factor and a substrate analog from the Mycobacterium tuberculosis ThyX active site: opportunities for anti-bacterial drug design.

  Journal of molecular biology 20060630

• Cell signaling. H2O2, a necessary evil for cell signaling.

  Science (New York, N.Y.) 20060630

• Defensive nature of Sargassum polycystum (Brown alga) against acetaminophen-induced toxic hepatitis in rats: role of drug metabolizing microsomal enzyme system, tumor necrosis factor-alpha and fate of liver cell structural integrity.

  World journal of gastroenterology 20060628

• Second messenger function of nicotinic acid adenine dinucleotide phosphate revealed by an improved enzymatic cycling assay.

  The Journal of biological chemistry 20060623

• Stability of membrane potential in heart mitochondria: single mitochondrion imaging.

  Biochemical and biophysical research communications 20060616

• Thr373, Asp375, and Lys260 are in the coenzyme site of porcine NADP-dependent isocitrate dehydrogenase.

  Archives of biochemistry and biophysics 20060615

• Characterization of a thermostable NADPH:FMN oxidoreductase from the mesophilic bacterium Bacillus subtilis.

  Biochemistry 20060613

• Messenger-specific role for nicotinic acid adenine dinucleotide phosphate in neuronal differentiation.

  The Journal of biological chemistry 20060609

• Hypoxia promotes relaxation of bovine coronary arteries through lowering cytosolic NADPH.

  American journal of physiology. Heart and circulatory physiology 20060601

• Function of mitochondria during the transition of barley protoplasts from low light to high light.

  Planta 20060601

• Diphenylhydantoin suppresses glucose-induced insulin release by decreasing cytoplasmic H+ concentration in pancreatic islets.

  Endocrinology 20060601

• NAADP and InsP3 play distinct roles at fertilization in starfish oocytes.

  Developmental biology 20060601

• Metabolism of a liver-selective nitric oxide-releasing agent, V-PYRRO/NO, by human microsomal cytochromes P450.

  Nitric oxide : biology and chemistry 20060601

• Nitric oxide biosynthesis by Leishmania amazonensis promastigotes containing a high percentage of metacyclic forms.

  Archives of microbiology 20060601

• Structure and function of glucose-6-phosphate dehydrogenase-deficient variants in Chinese population.

  Human genetics 20060601

• Nandrolone decanoate impairs exercise-induced cardioprotection: role of antioxidant enzymes.

  The Journal of steroid biochemistry and molecular biology 20060601

• Long-term administration of rho-kinase inhibitor ameliorates renal damage in malignant hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20060601

• 11beta-Hydroxysteroid dehydrogenase activity in pregnancies complicated by hydatidiform mole.

  American journal of reproductive immunology (New York, N.Y. : 1989) 20060601

• The prediction of isotopic patterns in phenylpropanoids from their precursors and the mechanism of the NIH-shift: basis of the isotopic characteristics of natural aromatic compounds.

  Phytochemistry 20060601

• An NADPH and FAD dependent enzyme catalyzes hydroxylation of flavonoids in position 8.

  Phytochemistry 20060601

• Chlorogenic acid attenuates hypertension and improves endothelial function in spontaneously hypertensive rats.

  Journal of hypertension 20060601

• Hydrogen transfer pathways of the asymmetric reduction of alpha,beta-unsaturated ketone mediated by baker's yeast.

  Bioorganic chemistry 20060601

• Endothelial cell superoxide anion radical generation is not dependent on endothelial nitric oxide synthase-serine 1179 phosphorylation and endothelial nitric oxide synthase dimer/monomer distribution.

  Free radical biology & medicine 20060601

• Characterization of E. coli tetrameric aldehyde dehydrogenases with atypical properties compared to other aldehyde dehydrogenases.

  Protein science : a publication of the Protein Society 20060601

• A study on the antioxidant activities of some new benzazole derivatives.

  Acta biologica Hungarica 20060601

• [The relationship between oxidized form glutathione, coenzyme II and carotid artery atherosclerosis].

  Zhonghua xin xue guan bing za zhi 20060601

• [Drug-induced liver injury].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20060601

• Glyoxal markedly compromises hepatocyte resistance to hydrogen peroxide.

  Biochemical pharmacology 20060528

• Uncoupling of cytochrome P450 1A and stimulation of reactive oxygen species production by co-planar polychlorinated biphenyl congeners.

  Aquatic toxicology (Amsterdam, Netherlands) 20060525

• Crystal structure of isoflavone reductase from alfalfa (Medicago sativa L.).

  Journal of molecular biology 20060519

• The role of invariant amino acid residues at the hydride transfer site of proton-translocating transhydrogenase.

  The Journal of biological chemistry 20060512

• Crystal structures and catalytic mechanism of the Arabidopsis cinnamyl alcohol dehydrogenases AtCAD5 and AtCAD4.

  Organic & biomolecular chemistry 20060507

• NADPH-induced contractions of mouse aorta do not involve NADPH oxidase: a role for P2X receptors.

  The Journal of pharmacology and experimental therapeutics 20060501

• NADPH analog binding to constitutive nitric oxide activates electron transfer and NO synthesis.

  Nitric oxide : biology and chemistry 20060501

• Response surface methodology as an approach to determine the optimal activities of xylose reductase and xylitol dehydrogenase enzymes from Candida Mogii.

  Applied microbiology and biotechnology 20060501

• Detection of a new N-oxidized metabolite of flutamide, N-[4-nitro-3-(trifluoromethyl)phenyl]hydroxylamine, in human liver microsomes and urine of prostate cancer patients.

  Drug metabolism and disposition: the biological fate of chemicals 20060501

• The decrease of NAD(P)H has a prominent role in dopamine toxicity.

  Biochimica et biophysica acta 20060501

• Nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose regulate TRPM2 channels in T lymphocytes.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060501

• Variation of milk citrate with stage of lactation and de novo fatty acid synthesis in dairy cows.

  Journal of dairy science 20060501

• Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver.

  Hepatology (Baltimore, Md.) 20060501

• Reoxidation of cytosolic NADPH in Kluyveromyces lactis.

  FEMS yeast research 20060501

• Expression of cytosolic NADP+-dependent isocitrate dehydrogenase in bovine mammary epithelium: Modulation by regulators of differentiation and metabolic effectors.

  Experimental biology and medicine (Maywood, N.J.) 20060501

• Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid.

  Nature structural & molecular biology 20060501

• Changes in activation states of murine polymorphonuclear leukocytes (PMN) during inflammation: a comparison of bone marrow and peritoneal exudate PMN.

  Clinical and vaccine immunology : CVI 20060501

• Ultraviolet-induced autofluorescence characterization of normal and tumoral esophageal epithelium cells with quantitation of NAD(P)H.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20060501

• Hep27, a member of the short-chain dehydrogenase/reductase family, is an NADPH-dependent dicarbonyl reductase expressed in vascular endothelial tissue.

  Cellular and molecular life sciences : CMLS 20060501

• Effect of heparin on viologen-stimulated enzymatic NADH depletion.

  Chemical research in toxicology 20060501

• Optimizing a biocatalyst for improved NAD(P)H regeneration: directed evolution of phosphite dehydrogenase.

  Combinatorial chemistry & high throughput screening 20060501

• A lag-phase in the reduction of flavin dependent thymidylate synthase (FDTS) revealed a mechanistic missing link.

  Chemical communications (Cambridge, England) 20060428

• Glucose-6-phosphate dehydrogenase activity and NADPH/NADP+ ratio in liver and pancreas are dependent on the severity of hyperglycemia in rat.

  Life sciences 20060425

• Crystal structures of the short-chain flavin reductase HpaC from Sulfolobus tokodaii strain 7 in its three states: NAD(P)(+)(-)free, NAD(+)(-)bound, and NADP(+)(-)bound.

  Biochemistry 20060425

• Motexafin gadolinium, a tumor-selective drug targeting thioredoxin reductase and ribonucleotide reductase.

  The Journal of biological chemistry 20060421

• Exploitation of the alcohol dehydrogenase-acetone NADP-regeneration system for the enzymatic preparative-scale production of 12-ketochenodeoxycholic acid.

  Biotechnology and bioengineering 20060420

• Analysis of the enzymatic formation of citral in the glands of sweet basil.

  Archives of biochemistry and biophysics 20060415

• Ca2+ release triggered by NAADP in hepatocyte microsomes.

  The Biochemical journal 20060415

• Ca2+ controls slow NAD(P)H oscillations in glucose-stimulated mouse pancreatic islets.

  The Journal of physiology 20060415

• NMR study of the electron transfer complex of plant ferredoxin and sulfite reductase: mapping the interaction sites of ferredoxin.

  The Journal of biological chemistry 20060414

• Resveratrol inhibits gentamicin-induced mesangial cell contraction.

  Life sciences 20060411

• Interaction between mitochondrial CYP27B1 and adrenodoxin: role of arginine 458 of mouse CYP27B1.

  Biochemistry 20060411

• Arginine 276 controls the directional preference of AKR1C9 (rat liver 3alpha-hydroxysteroid dehydrogenase) in human embryonic kidney 293 cells.

  Endocrinology 20060401

• Substrate-free structure of a monomeric NADP isocitrate dehydrogenase: an open conformation phylogenetic relationship of isocitrate dehydrogenase.

  Proteins 20060401

• A nonradioisotope, enzymatic assay for 2-deoxyglucose uptake in L6 skeletal muscle cells cultured in a 96-well microplate.

  Analytical biochemistry 20060401

• 17Beta-hydroxysteroid dehydrogenase (17beta-HSD) in scleractinian corals and zooxanthellae.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060401

• Studies on the late steps of (+) pisatin biosynthesis: evidence for (-) enantiomeric intermediates.

  Phytochemistry 20060401

• Laboratory evolution of P450 BM-3 for mediated electron transfer.

  Chembiochem : a European journal of chemical biology 20060401

• Angiotensin II-stimulated collagen production in cardiac fibroblasts is mediated by reactive oxygen species.

  Journal of hypertension 20060401

• Formation of 4'-carboxyl acid metabolite of imrecoxib by rat liver microsomes.

  Acta pharmacologica Sinica 20060401

• Rat 3alpha-hydroxysteroid dehydrogenase: to oxidize or reduce, that is the question.

  Endocrinology 20060401

• H2O2 injury in beta thalassemic erythrocytes: protective role of catalase and the prooxidant effects of GSH.

  Free radical biology & medicine 20060401

• Mechanisms of time-dependent potentiation of insulin release: involvement of nitric oxide synthase.

  Diabetes 20060401

• Detection of superoxide anion generation by equine spermatozoa.

  American journal of veterinary research 20060401

• Structure of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Synechococcus PCC7942 complexed with NADP.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060401

• Evaluation of microsomal incubation conditions on CYP3A4-mediated metabolism of cyclosporine A by a statistical experimental design.

  Current drug metabolism 20060401

• Biochemical characterization and crystal structure of Synechocystis arogenate dehydrogenase provide insights into catalytic reaction.

  Structure (London, England : 1993) 20060401

• Estrogen metabolism and breast cancer risk--a review.

  African journal of reproductive health 20060401

• Direct measurement by laser flash photolysis of intramolecular electron transfer in a two-domain construct of murine inducible nitric oxide synthase.

  Journal of the American Chemical Society 20060322

• Crystal structure of a bifunctional deaminase and reductase from Bacillus subtilis involved in riboflavin biosynthesis.

  The Journal of biological chemistry 20060317

• Rotenone-like action of the branched-chain phytanic acid induces oxidative stress in mitochondria.

  The Journal of biological chemistry 20060317

• Endothelial nitric oxide synthase reduces nitrite anions to NO under anoxia.

  Biochemical and biophysical research communications 20060317

• Coenzyme Q(1) depletes NAD(P)H and impairs recycling of ascorbate in astrocytes.

  Brain research 20060317

• Disulfiram irreversibly aggregates betaine aldehyde dehydrogenase--a potential target for antimicrobial agents against Pseudomonas aeruginosa.

  Biochemical and biophysical research communications 20060310

• The first crystal structure of a thioacylenzyme intermediate in the ALDH family: new coenzyme conformation and relevance to catalysis.

  Biochemistry 20060307

• The expression of a Pichia stipitis xylose reductase mutant with higher K(M) for NADPH increases ethanol production from xylose in recombinant Saccharomyces cerevisiae.

  Biotechnology and bioengineering 20060305

• Effects of co-operative ligand binding on protein amide NH hydrogen exchange.

  Journal of molecular biology 20060303

• Two distinct Ca2+ compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets.

  Cellular signalling 20060301

• Construction of a two-strain system for asymmetric reduction of ethyl 4-chloro-3-oxobutanoate to (S)-4-chloro-3-hydroxybutanoate ethyl ester.

  Applied microbiology and biotechnology 20060301

• Evaluation of aldose reductase inhibition and docking studies of some secondary metabolites, isolated from Origanum vulgare L. ssp. hirtum.

  Bioorganic & medicinal chemistry 20060301

• Enzymic analysis of NADPH metabolism in beta-lactam-producing Penicillium chrysogenum: presence of a mitochondrial NADPH dehydrogenase.

  Metabolic engineering 20060301

• Thiol oxidation inhibits nitric oxide-mediated pulmonary artery relaxation and guanylate cyclase stimulation.

  American journal of physiology. Lung cellular and molecular physiology 20060301

• A transport mechanism for NAADP in a rat basophilic cell line.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301

• Molecular recognition between protein and nicotinamide dinucleotide in intact, proton-translocating transhydrogenase studied by ATR-FTIR Spectroscopy.

  Journal of the American Chemical Society 20060301

• Scavenging of reactive oxygen species by Eriobotrya japonica seed extract.

  Biological & pharmaceutical bulletin 20060301

• Structure-guided engineering of xylitol dehydrogenase cosubstrate specificity.

  Structure (London, England : 1993) 20060301

• Inhibition of CYP6B1-mediated detoxification of xanthotoxin by plant allelochemicals in the black swallowtail (Papilio polyxenes).

  Journal of chemical ecology 20060301

• Transcription analysis of recombinant saccharomyces cerevisiae reveals novel responses to xylose.

  Applied biochemistry and biotechnology 20060301

• Effects of excess corticosterone on NADPH generating enzymes and glucose oxidation in Leydig cells of adult rats.

  Human & experimental toxicology 20060301

• A novel aspect of NADPH production in ageing Penicillium chrysogenum.

  Acta biologica Hungarica 20060301

• Metabolic signalling in defence and stress: the central roles of soluble redox couples.

  Plant, cell & environment 20060301

• Uncoupled redox systems in the lumen of the endoplasmic reticulum. Pyridine nucleotides stay reduced in an oxidative environment.

  The Journal of biological chemistry 20060224

• Glyceraldehyde dehydrogenases from the thermoacidophilic euryarchaeota Picrophilus torridus and Thermoplasma acidophilum, key enzymes of the non-phosphorylative Entner-Doudoroff pathway, constitute a novel enzyme family within the aldehyde dehydrogenase superfamily.

  FEBS letters 20060220

• Hydrogen peroxide is a mediator of indole-3-acetic acid/horseradish peroxidase-induced apoptosis.

  FEBS letters 20060220

• Effect of the anti-anginal agent, perhexiline, on neutrophil, valvular and vascular superoxide formation.

  European journal of pharmacology 20060215

• Crystal structure of mouse succinic semialdehyde reductase AKR7A5: structural basis for substrate specificity.

  Biochemistry 20060214

• Global effects of the energetics of coenzyme binding: NADPH controls the protein interaction properties of human cytochrome P450 reductase.

  Biochemistry 20060207

• In silico design and synthesis of piperazine-1-pyrrolidine-2,5-dione scaffold-based novel malic enzyme inhibitors.

  Bioorganic & medicinal chemistry letters 20060201

• Calcium mobilization by nicotinic acid adenine dinucleotide phosphate (NAADP) in rat astrocytes.

  Cell calcium 20060201

• Mechanisms of gamma-glutamylcysteine ligase regulation.

  Biochimica et biophysica acta 20060201

• Catalysis of NADH-->NADP+ transhydrogenation by adult Hymenolepis diminuta mitochondria.

  Parasitology research 20060201

• Utilization of substrate-induced quenching for screening targets promoting NADH and NADPH consumption.

  Journal of biomolecular screening 20060201

• Molecular cloning and heterologous expression of progesterone 5beta-reductase from Digitalis lanata Ehrh.

  Phytochemistry 20060201

• Tropinone reductases, enzymes at the branch point of tropane alkaloid metabolism.

  Phytochemistry 20060201

• Multiplicity of mammalian reductases for xenobiotic carbonyl compounds.

  Drug metabolism and pharmacokinetics 20060201

• Role of epoxide hydrolase, NAD(P)H:quinone oxidoreductase, cytochrome P450 2E1 or alcohol dehydrogenase genotypes in susceptibility to colorectal cancer.

  Mutation research 20060129

• Structure of Chlorobium tepidum sepiapterin reductase complex reveals the novel substrate binding mode for stereospecific production of L-threo-tetrahydrobiopterin.

  The Journal of biological chemistry 20060127

• Identification of the mitochondrial NAD+ transporter in Saccharomyces cerevisiae.

  The Journal of biological chemistry 20060120

• Kinetic, inhibition and structural studies on 3-oxoacyl-ACP reductase from Plasmodium falciparum, a key enzyme in fatty acid biosynthesis.

  The Biochemical journal 20060115

• NAADP, cADPR and IP3 all release Ca2+ from the endoplasmic reticulum and an acidic store in the secretory granule area.

  Journal of cell science 20060115

• Essential role of aralar in the transduction of small Ca2+ signals to neuronal mitochondria.

  The Journal of biological chemistry 20060113

• Mechanistic implications of the structure of the mixed-disulfide intermediate of the disulfide oxidoreductase, 2-ketopropyl-coenzyme M oxidoreductase/carboxylase.

  Biochemistry 20060110

• Evidence that the 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD1) is regulated by pentose pathway flux. Studies in rat adipocytes and microsomes.

  The Journal of biological chemistry 20060106

• Glucose-6-phosphate dehydrogenase regulation during hypometabolism.

  Biochemical and biophysical research communications 20060106

• Methoxy-resorufin ether as an electrochemically active biological probe for cytochrome P450 O-demethylation.

  Bioelectrochemistry (Amsterdam, Netherlands) 20060101

• A biosynthetic pathway generating 12-hydroxy-5,8,14-eicosatrienoic acid from arachidonic acid is active in mouse skin microsomes.

  The Journal of pharmacology and experimental therapeutics 20060101

• Inactivation of CYP2A6 and CYP2A13 during nicotine metabolism.

  The Journal of pharmacology and experimental therapeutics 20060101

• Role of pentose phosphate pathway-derived NADPH in hypoxic pulmonary vasoconstriction.

  Pulmonary pharmacology & therapeutics 20060101

• Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats.

  Drug metabolism and disposition: the biological fate of chemicals 20060101

• Mode of mitochondrial Ca2+ clearance and its influence on secretory responses in stimulated chromaffin cells.

  Cell calcium 20060101

• Non-oxygen-forming pathways of hydrogen peroxide degradation by bovine liver catalase at low hydrogen peroxide fluxes.

  Free radical research 20060101

• A streamlined method to predict hepatic clearance using human liver microsomes in the presence of human plasma.

  Journal of pharmacological and toxicological methods 20060101

• Intricacies of brain angiotensin II signalling pathways.

  Journal of hypertension 20060101

• In vitro induction of nitric oxide by mouse peritoneal macrophages treated with human placental extract.

  International immunopharmacology 20060101

• Angiotensin II infusion alters vascular function in mouse resistance vessels: roles of O and endothelium.

  Journal of vascular research 20060101

• Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin secretion in pancreatic beta-cells.

  Diabetes 20060101

• Identification of sn-glycerol-1-phosphate dehydrogenase activity from genomic information on a hyperthermophilic archaeon, Sulfolobus tokodaii strain 7.

  Bioscience, biotechnology, and biochemistry 20060101

• The Ca2+-releasing messenger NAADP, a new player in the nervous system.

  Journal of physiology, Paris 20060101

• Crystallization and preliminary diffraction studies of malate dehydrogenase from Streptomyces aureofaciens.

  Protein and peptide letters 20060101

• Subcellular localization of Strboh proteins and NADPH-dependent O2(-)-generating activity in potato tuber tissues.

  Journal of experimental botany 20060101

• Antioxidant protective mechanisms against reactive oxygen species (ROS) generated by mitochondrial P450 systems in steroidogenic cells.

  Drug metabolism reviews 20060101

• NAD(P) synthesis and pyridine nucleotide cycling in plants and their potential importance in stress conditions.

  Journal of experimental botany 20060101

• Mitochondrial NADPH, transhydrogenase and disease.

  Biochimica et biophysica acta 20060101

• No association between a functional NAD(P)H: quinone oxidoreductase gene polymorphism (Pro187Ser) and tardive dyskinesia.

  Neuromolecular medicine 20060101

• The hypothalamic supraoptic and paraventricular nuclei of the echidna and platypus.

  Brain, behavior and evolution 20060101

• Glucose 6-phosphate dehydrogenase overexpression models glucose deprivation and sensitizes lymphoma cells to apoptosis.

  Antioxidants & redox signaling 20060101

• Effects of irsogladine on P450-isoform specific activities in human hepatic microsomes.

  Arzneimittel-Forschung 20060101

• Reduction of nitroaromatic compounds by NAD(P)H:quinone oxidoreductase (NQO1): the role of electron-accepting potency and structural parameters in the substrate specificity.

  Acta biochimica Polonica 20060101

• Evidence for chronic, peripheral activation of neutrophils in polyarticular juvenile rheumatoid arthritis.

  Arthritis research & therapy 20060101

• Asymmetric reduction of o-chloroacetophenone with Candida pseudotropicalis 104.

  Biotechnology progress 20060101

• [Stabilization of glucoso-6-phosphate dehydrogenase by its substrate and cofactor in an ultrasonic field].

  Bioorganicheskaia khimiia 20060101

• [Change of the nitric oxide synthase activity after administration of neurotoxic compounds in mice].

  Acta pharmaceutica Hungarica 20060101

• Catalases are NAD(P)H-dependent tellurite reductases.

  PloS one 20060101

• Prooxidant cytotoxicity of chromate in mammalian cells: the opposite roles of DT-diaphorase and glutathione reductase.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101

• [Role of glycolysis in initiation of immortality and apoptosis].

  Voprosy onkologii 20060101

• Emerging functions of extracellular pyridine nucleotides.

  Molecular medicine (Cambridge, Mass.) 20060101

• Acquisition of iron by enterococci: some properties and role of assimilating ferric iron reductases.

  Polish journal of microbiology 20060101

• Substrate recognition by the human fatty-acid synthase.

  The Journal of biological chemistry 20051230

• Glucose-sensing mechanisms in pancreatic beta-cells.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20051229

• Conformation coupled enzyme catalysis: single-molecule and transient kinetics investigation of dihydrofolate reductase.

  Biochemistry 20051227

• Characterization of kinetics and products of the Baeyer-Villiger oxygenase MtmOIV, the key enzyme of the biosynthetic pathway toward the natural product anticancer drug mithramycin from Streptomyces argillaceus.

  Journal of the American Chemical Society 20051221

• Aerobic 2- and 4-nitroreduction of CB 1954 by human liver.

  Toxicology 20051215

• Functional coupling between vanillate-O-demethylase and formaldehyde detoxification pathway.

  FEMS microbiology letters 20051215

• Induction of apoptosis by the overexpression of an alternative splicing variant of mitochondrial thioredoxin reductase.

  Free radical biology & medicine 20051215

• Nebivolol reduces nitroxidative stress and restores nitric oxide bioavailability in endothelium of black Americans.

  Circulation 20051213

• A cytosolic cytochrome b5-like protein in yeast cell accelerating the electron transfer from NADPH to cytochrome c catalyzed by Old Yellow Enzyme.

  Biochemical and biophysical research communications 20051209

• Crystal structures of Delta1-piperideine-2-carboxylate/Delta1-pyrroline-2-carboxylate reductase belonging to a new family of NAD(P)H-dependent oxidoreductases: conformational change, substrate recognition, and stereochemistry of the reaction.

  The Journal of biological chemistry 20051209

• Sources of NADPH in yeast vary with carbon source.

  The Journal of biological chemistry 20051202

• Analysis of coumarin 7-hydroxylation activity of cytochrome P450 2A6 using random mutagenesis.

  The Journal of biological chemistry 20051202

• Stereo-specificity for pro-(R) hydrogen of NAD(P)H during enzyme-catalyzed hydride transfer to CL-20.

  Biochemical and biophysical research communications 20051202

• Metabolic aspects of aspirin-induced apoptosis in yeast.

  FEMS yeast research 20051201

• A preliminary account of the properties of recombinant human Glyoxylate reductase (GRHPR), LDHA and LDHB with glyoxylate, and their potential roles in its metabolism.

  Biochimica et biophysica acta 20051201

• Free radical scavenging and antigenotoxic activities of natural phenolic compounds in dried flowers of Hibiscus sabdariffa L.

  Molecular nutrition & food research 20051201

• Hemoglobin autoxidation and regulation of endogenous H2O2 levels in erythrocytes.

  Free radical biology & medicine 20051201

• Oxidized-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine induces vascular endothelial superoxide production: implication of NADPH oxidase.

  Free radical biology & medicine 20051201

• Circadian rhythm of a TCA cycle enzyme is apparently regulated at the translational level in the dinoflagellate Lingulodinium polyedrum.

  Journal of biological rhythms 20051201

• Functional characterisation of an engineered multidomain human P450 2E1 by molecular Lego.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20051201

• Postnatal development of cholinergic neurons in the mesopontine tegmentum revealed by histochemistry.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20051201

• The effect of alpha-phenyl-N-t-butylnitrone on ionizing radiation-induced apoptosis in U937 cells.

  Free radical research 20051201

• Conformational flexibility of Mycobacterium tuberculosis thioredoxin reductase: crystal structure and normal-mode analysis.

  Acta crystallographica. Section D, Biological crystallography 20051201

• Kinetic characterisation of the light-driven protochlorophyllide oxidoreductase (POR) from Thermosynechococcus elongatus.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20051201

• Oxidant release is dramatically increased by elevated glucose concentrations in neutrophils from pregnant women.

  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20051201

• Poly-beta-hydroxybutyrate accumulation in Nostoc muscorum and Spirulina platensis under phosphate limitation.

  Journal of plant physiology 20051201

• Improved expression, purification and crystallization of a putative N-acetyl-gamma-glutamyl-phosphate reductase from rice (Oryza sativa).

  Acta crystallographica. Section F, Structural biology and crystallization communications 20051201

• Antioxidant profiles in full term and preterm neonates.

  Chang Gung medical journal 20051201

• The effect of quercetin and galangin on glutathione reductase.

  Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20051201

• A comparative study of neuronal and inducible nitric oxide synthases: generation of nitric oxide, superoxide, and hydrogen peroxide.

  Biochimica et biophysica acta 20051130

• C-terminal tail residue Arg1400 enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase.

  The Journal of biological chemistry 20051125

• High-resolution crystal structure of AKR11C1 from Bacillus halodurans: an NADPH-dependent 4-hydroxy-2,3-trans-nonenal reductase.

  Journal of molecular biology 20051125

• Crystal structures of an NAD kinase from Archaeoglobus fulgidus in complex with ATP, NAD, or NADP.

  Journal of molecular biology 20051125

• Reconstitution of an apicoplast-localised electron transfer pathway involved in the isoprenoid biosynthesis of Plasmodium falciparum.

  FEBS letters 20051121

• Oxalomalate, a competitive inhibitor of NADP+-dependent isocitrate dehydrogenase, regulates heat shock-induced apoptosis.

  Biochemical and biophysical research communications 20051118

• Coronary microvascular endothelial cell growth regulates expression of the gene encoding p22-phox.

  Free radical biology & medicine 20051115

• NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries.

  Circulation research 20051111

• Biosynthesis of isoprenoids. purification and properties of IspG protein from Escherichia coli.

  The Journal of organic chemistry 20051111

• Temporal changes of multiple redox couples from proliferation to growth arrest in IEC-6 intestinal epithelial cells.

  American journal of physiology. Cell physiology 20051101

• Ligand binding modulates the mechanical stability of dihydrofolate reductase.

  Biophysical journal 20051101

• Molecular cloning and functional expression of d-arabitol dehydrogenase gene from Gluconobacter oxydans in Escherichia coli.

  FEMS microbiology letters 20051101

• Influence of substrate binding on the mechanical stability of mouse dihydrofolate reductase.

  Biophysical journal 20051101

• Biochemical characterization of trinitrotoluene transforming oxygen-insensitive nitroreductases from Clostridium acetobutylicum ATCC 824.

  Archives of microbiology 20051101

• NADK2, an Arabidopsis chloroplastic NAD kinase, plays a vital role in both chlorophyll synthesis and chloroplast protection.

  Plant molecular biology 20051101

• Single amino acid exchanges in FAD-binding domains of squalene epoxidase of Saccharomyces cerevisiae lead to either loss of functionality or terbinafine sensitivity.

  Biochemical Society transactions 20051101

• Purification, characterization, and overexpression of psychrophilic and thermolabile malate dehydrogenase of a novel antarctic psychrotolerant, Flavobacterium frigidimaris KUC-1.

  Bioscience, biotechnology, and biochemistry 20051101

• In vitro metabolism of a new cardioprotective agent, KR-33028 in the human liver microsomes and cryopreserved human hepatocytes.

  Archives of pharmacal research 20051101

• Inhibition of neuronal nitric-oxide synthase by phosphorylation at Threonine1296 in NG108-15 neuronal cells.

  FEBS letters 20051024

• NAD-, NMN-, and NADP-dependent modification of dinitrogenase reductases from Rhodospirillum rubrum and Azotobacter vinelandii.

  FEBS letters 20051024

• Role of cytochrome P-450 in schisandrin B-induced antioxidant and heat shock responses in mouse liver.

  Life sciences 20051021

• Extracellular application of nicotinic acid adenine dinucleotide phosphate induces Ca2+ signaling in astrocytes in situ.

  The Journal of biological chemistry 20051021

• Dynamic changes in nicotinamide pyridine dinucleotide content in normal human epidermal keratinocytes and their effect on retinoic acid biosynthesis.

  Biochemical and biophysical research communications 20051021

• Evolution. Changing the cofactor diet of an enzyme.

  Science (New York, N.Y.) 20051021

• The biochemical architecture of an ancient adaptive landscape.

  Science (New York, N.Y.) 20051021

• C-terminal tyrosine of ferredoxin-NADP+ reductase in hydride transfer processes with NAD(P)+/H.

  Biochemistry 20051018

• Formation of M1G-dR from endogenous and exogenous ROS-inducing chemicals.

  Free radical biology & medicine 20051015

• Organization of protochlorophyllide oxidoreductase in prolamellar bodies isolated from etiolated carotenoid-deficient wheat leaves as revealed by fluorescence probes.

  Biochimica et biophysica acta 20051015

• Post-translational regulation of mercaptopyruvate sulfurtransferase via a low redox potential cysteine-sulfenate in the maintenance of redox homeostasis.

  The Journal of biological chemistry 20051014

• Kinetics of proton-linked flavin conformational changes in p-hydroxybenzoate hydroxylase.

  Biochemistry 20051011

• Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2.

  Cell 20051007

• Purification and characterization of NAD(P)H-dependent nitroreductase I from Klebsiella sp. C1 and enzymatic transformation of 2,4,6-trinitrotoluene.

  Applied microbiology and biotechnology 20051001

• Enzyme kinetics of zearalenone biotransformation: pH and cofactor effects.

  Archives of toxicology 20051001

• Oxygen availability limits renal NADPH-dependent superoxide production.

  American journal of physiology. Renal physiology 20051001

• Metabolic dysfunction during neuronal activation in the ex vivo hippocampus from chronic epileptic rats and humans.

  Brain : a journal of neurology 20051001

• Aluminum-tolerant Pseudomonas fluorescens: ROS toxicity and enhanced NADPH production.

  Extremophiles : life under extreme conditions 20051001

• Direct quantification of analyte concentration by resonant acoustic profiling.

  Clinical chemistry 20051001

• Aprotinin attenuated ischemia-reperfusion injury in an isolated rat lung model after 18-hours preservation.

  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20051001

• Interactions between dehydroepiandrosterone and glucocorticoid metabolism in pig kidney: nuclear and microsomal 11beta-hydroxysteroid dehydrogenases.

  Archives of biochemistry and biophysics 20051001

• Nitric oxide control of lower vertebrate blood vessels by vasomotor nerves.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20051001

• NAD- and NADP-dependent mitochondrially targeted methylenetetrahydrofolate dehydrogenase-cyclohydrolases can rescue mthfd2 null fibroblasts.

  Archives of biochemistry and biophysics 20051001

• Crystal structure of Trypanosoma cruzi pteridine reductase 2 in complex with a substrate and an inhibitor.

  Journal of structural biology 20051001

• Lipopolysaccharide-induced alterations in oxygen consumption and radical generation in endothelial cells.

  Molecular and cellular biochemistry 20051001

• Effect of pollen-mediated oxidative stress on immediate hypersensitivity reactions and late-phase inflammation in allergic conjunctivitis.

  The Journal of allergy and clinical immunology 20051001

• Androgen metabolism via 17beta-hydroxysteroid dehydrogenase type 3 in mammalian and non-mammalian vertebrates: comparison of the human and the zebrafish enzyme.

  Journal of molecular endocrinology 20051001

• Stimulatory effects of testosterone and progesterone on the NADH- and NADPH-dependent oxidation of 7beta-hydroxy-delta8-tetrahydrocannabinol to 7-oxo-delta8-tetrahydrocannabinol in monkey liver microsomes.

  Drug metabolism and pharmacokinetics 20051001

• Initiation of a superoxide-dependent chain oxidation of lactate dehydrogenase-bound NADH by oxidants of low and high reactivity.

  Free radical research 20051001

• Effect of 2,4-dichlorophenoxyacetic acid on the activities of some metabolic enzymes for generating pyridine nucleotide pool of cells from mouse liver.

  Toxicology and industrial health 20051001

• Crystallization and preliminary X-ray crystallographic analysis of Sulfolobus solfataricus thioredoxin reductase.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20051001

• Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20051001

• Crystal structure of novel NADP-dependent 3-hydroxyisobutyrate dehydrogenase from Thermus thermophilus HB8.

  Journal of molecular biology 20050930

• Expression, purification and properties of shikimate dehydrogenase from Mycobacterium tuberculosis.

  Journal of biochemistry and molecular biology 20050930

• NovJ/NovK catalyze benzylic oxidation of a beta-hydroxyl tyrosyl-S-pantetheinyl enzyme during aminocoumarin ring formation in novobiocin biosynthesis.

  Biochemistry 20050927

• X-ray structures of NADPH-dependent carbonyl reductase from Sporobolomyces salmonicolor provide insights into stereoselective reductions of carbonyl compounds.

  Journal of molecular biology 20050923

• Calorimetric studies of ligand binding in R67 dihydrofolate reductase.

  Biochemistry 20050920

• Coenzyme binding during catalysis is beneficial for the stability of 4-hydroxyacetophenone monooxygenase.

  The Journal of biological chemistry 20050916

• Cytochrome P450/NADPH-dependent biosynthesis of 5,6-trans-epoxyeicosatrienoic acid from 5,6-trans-arachidonic acid.

  The Biochemical journal 20050915

• Evaluation of alpha-cyano ethers as fluorescent substrates for assay of cytochrome P450 enzyme activity.

  Analytical biochemistry 20050915

• The ferredoxin-NADP(H) reductase from Rhodobacter capsulatus: molecular structure and catalytic mechanism.

  Biochemistry 20050906

• The human apoptosis-inducing protein AMID is an oxidoreductase with a modified flavin cofactor and DNA binding activity.

  The Journal of biological chemistry 20050902

• Expression of functionally phagocyte-type NAD(P)H oxidase in pericytes: effect of angiotensin II and high glucose.

  Biology of the cell 20050901

• Pyridine nucleotides and calcium signalling in arterial smooth muscle: from cell physiology to pharmacology.

  Pharmacology & therapeutics 20050901

• Marked decrease in specific activity contributes to disease phenotype in two human glucose 6-phosphate dehydrogenase mutants, G6PD(Union) and G6PD(Andalus).

  Human mutation 20050901

• Melatonin restores the cytochrome oxidase reactivity in the nodose ganglia of acute hypoxic rats.

  Journal of pineal research 20050901

• Effect of calcium chloride, zinc chloride, and water infusion on metmyoglobin reducing activity and fresh lamb color.

  Journal of animal science 20050901

• Mechanism responsible for the decreased hepatic NADPH generation rate in rats with bilateral ureter ligation-induced renal failure.

  Biological & pharmaceutical bulletin 20050901

• New plastoquinones isolated from the brown alga, Sargassum micracanthum.

  Chemical & pharmaceutical bulletin 20050901

• A vital link between energy and signal transduction.

  The FEBS journal 20050901

• Calcium signalling by nicotinic acid adenine dinucleotide phosphate (NAADP).

  The FEBS journal 20050901

• Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH.

  Journal of biomolecular NMR 20050901

• Nitric oxide delays oocyte aging.

  Biochemistry 20050830

• Structural elucidation of chalcone reductase and implications for deoxychalcone biosynthesis.

  The Journal of biological chemistry 20050826

• Location of the coenzyme binding site in the porcine mitochondrial NADP-dependent isocitrate dehydrogenase.

  The Journal of biological chemistry 20050826

• Thioredoxin reductase system mediates iron binding in IscA and iron delivery for the iron-sulfur cluster assembly in IscU.

  The Journal of biological chemistry 20050826

• Crystal structure of NAD-dependent malate dehydrogenase complexed with NADP(H).

  Biochemical and biophysical research communications 20050826

• Identification in the mold Hypocrea jecorina of the first fungal D-galacturonic acid reductase.

  Biochemistry 20050823

• Structure of the tetrameric form of human L-Xylulose reductase: probing the inhibitor-binding site with molecular modeling and site-directed mutagenesis.

  Proteins 20050815

• Evaluation of the effect of oxygen exposure on human liver microsomal metabolism of mitomycin C in the presence of glutathione using liquid chromatography-quadrupole time of flight mass spectrometry.

  Analytical biochemistry 20050815

• Involvement of carbonyl reductase in superoxide formation through redox cycling of adrenochrome and 9,10-phenanthrenequinone in pig heart.

  Chemico-biological interactions 20050815

• Peptide nanotube-modified electrodes for enzyme-biosensor applications.

  Analytical chemistry 20050815

• 2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino)- phenylcarbamoylsulfanyl]propionic acid and its derivatives as a novel class of glutathione reductase inhibitors.

  Journal of medicinal chemistry 20050811

• Identification of the N- and C-terminal substrate binding segments of ferredoxin-NADP+ reductase by NMR.

  Biochemistry 20050809

• L-Threonine dehydrogenase from the hyperthermophilic archaeon Pyrococcus horikoshii OT3: gene cloning and enzymatic characterization.

  Extremophiles : life under extreme conditions 20050801

• Glucose-dependent changes in NAD(P)H-related fluorescence lifetime of adipocytes and fibroblasts in vitro: potential for non-invasive glucose sensing in diabetes mellitus.

  Journal of photochemistry and photobiology. B, Biology 20050801

• Oxidant and redox signaling in vascular oxygen sensing mechanisms: basic concepts, current controversies, and potential importance of cytosolic NADPH.

  American journal of physiology. Lung cellular and molecular physiology 20050801

• Interflavin one-electron transfer in the inducible nitric oxide synthase reductase domain and NADPH-cytochrome P450 reductase.

  Archives of biochemistry and biophysics 20050801

• A modified consensus approach to mutagenesis inverts the cofactor specificity of Bacillus stearothermophilus lactate dehydrogenase.

  Protein engineering, design & selection : PEDS 20050801

• Mechanistic investigation of a highly active phosphite dehydrogenase mutant and its application for NADPH regeneration.

  The FEBS journal 20050801

• p53 proteasomal degradation: poly-ubiquitination is not the whole story.

  Cell cycle (Georgetown, Tex.) 20050801

• Effects of naphthalene quinonoids on the induction of oxidative DNA damage and cytotoxicity in calf thymus DNA and in human cultured cells.

  Chemical research in toxicology 20050801

• Kinetic modeling of acetophenone reduction catalyzed by alcohol dehydrogenase from Thermoanaerobacter sp.

  Biotechnology letters 20050801

• Development and application of a scintillation proximity assay (SPA) for identification of selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.

  Assay and drug development technologies 20050801

• Crystallization and preliminary X-ray analysis of binary and ternary complexes of Haloferax mediterranei glucose dehydrogenase.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050801

• Characterization of the final step in the conversion of phytol into phytanic acid.

  The Journal of biological chemistry 20050722

• Electrostatic stabilization in a pre-organized polar active site: the catalytic role of Lys-80 in Candida tenuis xylose reductase (AKR2B5) probed by site-directed mutagenesis and functional complementation studies.

  The Biochemical journal 20050715

• Nucleotide binding affinities of the intact proton-translocating transhydrogenase from Escherichia coli.

  Biochimica et biophysica acta 20050715

• Human NAD(P)H:quinone oxidoreductase inhibition by flavonoids in living cells.

  Free radical biology & medicine 20050715

• Mangiferin, a natural occurring glucosyl xanthone, increases susceptibility of rat liver mitochondria to calcium-induced permeability transition.

  Archives of biochemistry and biophysics 20050715

• Docking, triggering, and biological activity of dynemicin A in DNA: a computational study.

  Journal of the American Chemical Society 20050706

• Transition metal complexes coordinated by an NAD(P)H model compound and their enhanced hydride-donating abilities in the presence of a base.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20050704

• A novel monothiol glutaredoxin (Grx4) from Escherichia coli can serve as a substrate for thioredoxin reductase.

  The Journal of biological chemistry 20050701

• Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity.

  The Journal of biological chemistry 20050701

• Physical and kinetic interactions between glutamyl-tRNA reductase and glutamate-1-semialdehyde aminotransferase of Chlamydomonas reinhardtii.

  The Journal of biological chemistry 20050701

• Roles of poly(ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications.

  Pharmacological research 20050701

• Identification of ATP-NADH kinase isozymes and their contribution to supply of NADP(H) in Saccharomyces cerevisiae.

  The FEBS journal 20050701

• Characterization of phytanic acid omega-hydroxylation in human liver microsomes.

  Molecular genetics and metabolism 20050701

• Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin.

  Diabetes 20050701

• Sequential conformation changes of chinese hamster ovary dihydrofolate reductase at its active sites.

  Protein and peptide letters 20050701

• Complete reversal of coenzyme specificity of isocitrate dehydrogenase from Haloferax volcanii.

  The protein journal 20050701

• Photosystem I lacking the PSI-G subunit has a higher affinity for plastocyanin and is sensitive to photodamage.

  Biochimica et biophysica acta 20050630

• The crystal structure of Escherichia coli ketopantoate reductase with NADP+ bound.

  Biochemistry 20050628

• Shape and color of au nanoparticles follow biocatalytic processes.

  Langmuir : the ACS journal of surfaces and colloids 20050621

• Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment.

  The Journal of biological chemistry 20050617

• Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates.

  The Biochemical journal 20050615

• Mechanistic studies with 2-C-methyl-D-erythritol 4-phosphate synthase from Escherichia coli.

  Biochemistry 20050614

• Efficient chemoenzymatic synthesis of ADP-D-glycero-beta-D-manno-heptose and a mechanistic study of ADP-L-glycero-D-manno-heptose 6-epimerase.

  Organic letters 20050609

• Functional ryanodine receptor expression is required for NAADP-mediated local Ca2+ signaling in T-lymphocytes.

  The Journal of biological chemistry 20050603

• Hydroxylation activity of P450 BM-3 mutant F87V towards aromatic compounds and its application to the synthesis of hydroquinone derivatives from phenolic compounds.

  Applied microbiology and biotechnology 20050601

• Voltage- and NADPH-dependence of electron currents generated by the phagocytic NADPH oxidase.

  The Biochemical journal 20050601

• Reduction of arsenate to arsenite by human erythrocyte lysate and rat liver cytosol - characterization of a glutathione- and NAD-dependent arsenate reduction linked to glycolysis.

  Toxicological sciences : an official journal of the Society of Toxicology 20050601

• Cytotoxic effects of 110 reference compounds on HepG2 cells and for 60 compounds on HeLa, ECC-1 and CHO cells. II mechanistic assays on NAD(P)H, ATP and DNA contents.

  Toxicology in vitro : an international journal published in association with BIBRA 20050601

• A Caenorhabditis elegans mutant lacking functional nicotinamide nucleotide transhydrogenase displays increased sensitivity to oxidative stress.

  Free radical biology & medicine 20050601

• Spectrofluorometric determination of trace amounts of coenzyme II using norfioxacin-terbium complex as a fluorescent probe.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20050601

• Relationship between immune status and activity of the lymphocyte energy supply system in adolescents suffering from frequent diseases.

  Bulletin of experimental biology and medicine 20050601

• Glucose suppresses superoxide generation in metabolically responsive pancreatic beta cells.

  The Journal of biological chemistry 20050527

• 2-Haloacrylate reductase, a novel enzyme of the medium chain dehydrogenase/reductase superfamily that catalyzes the reduction of a carbon-carbon double bond of unsaturated organohalogen compounds.

  The Journal of biological chemistry 20050527

• Mechanistic studies on a novel, highly potent gold-phosphole inhibitor of human glutathione reductase.

  The Journal of biological chemistry 20050527

• Cyanobacterial non-mevalonate pathway: (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase interacts with ferredoxin in Thermosynechococcus elongatus BP-1.

  The Journal of biological chemistry 20050527

• Escherichia coli quinolinate synthetase does indeed harbor a [4Fe-4S] cluster.

  Journal of the American Chemical Society 20050525

• The structure of Apo R268A human aldose reductase: hinges and latches that control the kinetic mechanism.

  Biochimica et biophysica acta 20050515

• Crystal structure of murine 11 beta-hydroxysteroid dehydrogenase 1: an important therapeutic target for diabetes.

  Biochemistry 20050510

• Role of NAADP and cADPR in the induction and maintenance of agonist-evoked Ca2+ spiking in mouse pancreatic acinar cells.

  Current biology : CB 20050510

• Switching pyridine nucleotide specificity in P450 BM3: mechanistic analysis of the W1046H and W1046A enzymes.

  The Journal of biological chemistry 20050506

• Stromal over-reduction by high-light stress as measured by decreases in P700 oxidation by far-red light and its physiological relevance.

  Plant & cell physiology 20050501

• Glucose-6-phosphate dehydrogenase and NADPH-consuming enzymes in the rat olfactory bulb.

  Journal of neuroscience research 20050501

• Bovine blastocyst development rate in vitro is influenced by selection of oocytes by brillant cresyl blue staining before IVM as indicator for glucose-6-phosphate dehydrogenase activity.

  Theriogenology 20050501

• Structural and kinetic basis for substrate selectivity in Populus tremuloides sinapyl alcohol dehydrogenase.

  The Plant cell 20050501

• Ca2+-induced permeabilization promotes free radical release from rat brain mitochondria with partially inhibited complex I.

  Journal of neurochemistry 20050501

• The sources of oxidative stress in the vessel wall.

  Kidney international 20050501

• Old yellow enzyme interferes with Bax-induced NADPH loss and lipid peroxidation in yeast.

  FEMS yeast research 20050501

• Purification of glutathione reductase from chicken liver and investigation of kinetic properties.

  Applied biochemistry and biotechnology 20050501

• Structural studies of glucose-6-phosphate and NADP+ binding to human glucose-6-phosphate dehydrogenase.

  Acta crystallographica. Section D, Biological crystallography 20050501

• The Calvin cycle in cyanobacteria is regulated by CP12 via the NAD(H)/NADP(H) ratio under light/dark conditions.

  The Plant journal : for cell and molecular biology 20050501

• Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050501

• Bioactivation of 4-ipomeanol by CYP4B1: adduct characterization and evidence for an enedial intermediate.

  Chemical research in toxicology 20050501

• Mechanistic studies on the metabolic scission of thiazolidinedione derivatives to acyclic thiols.

  Chemical research in toxicology 20050501

• Components of the cytochrome P450-dependent monooxygenase system and 'NADPH-independent benzo[a]pyrene hydroxylase' activity in a wide range of marine invertebrate species.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20050501

• Periodic fluctuations in oxygen consumption comparing HeLa (cancer) and CHO (non-cancer) cells and response to external NAD(P)+/NAD(P)H.

  Molecular and cellular biochemistry 20050501

• Glutathione system and activity of NADPH-generating enzymes in the liver of intact rats and animals with toxic hepatitis receiving melatonin.

  Bulletin of experimental biology and medicine 20050501

• Identification of a glucokinase that generates a major glucose phosphorylation activity in the cyanobacterium Synechocystis sp. PCC 6803.

  Molecules and cells 20050430

• Iso-coenzyme A.

  The Journal of biological chemistry 20050429

• Distinct conformation-mediated functions of an active site loop in the catalytic reactions of NAD-dependent D-lactate dehydrogenase and formate dehydrogenase.

  The Journal of biological chemistry 20050429

• Crystal structure of a novel shikimate dehydrogenase from Haemophilus influenzae.

  The Journal of biological chemistry 20050429

• Dismutase activity of ADP-L-glycero-D-manno-heptose 6-epimerase: evidence for a direct oxidation/reduction mechanism.

  Biochemistry 20050419

• The unexpected structural role of glutamate synthase [4Fe-4S](+1,+2) clusters as demonstrated by site-directed mutagenesis of conserved C residues at the N-terminus of the enzyme beta subunit.

  Archives of biochemistry and biophysics 20050415

• Hepatic arachidonic acid metabolism is disrupted after hexachlorobenzene treatment.

  Toxicology and applied pharmacology 20050415

• Human endothelial nitric oxide synthase gene delivery protects against cardiac remodeling and reduces oxidative stress after myocardial infarction.

  Life sciences 20050408

• The Arg280His polymorphism in X-ray repair cross-complementing gene 1 impairs DNA repair ability.

  Mutation research 20050404

• Involvement of the pentose phosphate pathway and redox regulation in fertilization in the mouse.

  Molecular reproduction and development 20050401

• Modulation of cooperativity in Mycobacterium tuberculosis NADPH-ferredoxin reductase: cation-and pH-induced alterations in native conformation and destabilization of the NADP+-binding domain.

  Protein science : a publication of the Protein Society 20050401

• Metabolite-cytochrome P450 complex formation by methylenedioxyphenyl lignans of Piper cubeba: mechanism-based inhibition.

  Life sciences 20050401

• Vitamin C homeostasis in skeletal muscle cells.

  Free radical biology & medicine 20050401

• Towards a new interaction enzyme:coenzyme.

  Biophysical chemistry 20050401

• Measurement and characterization of C-3 epimerization activity toward vitamin D3.

  Archives of biochemistry and biophysics 20050401

• Structural basis of eukaryotic nitrate reduction: crystal structures of the nitrate reductase active site.

  The Plant cell 20050401

• Metabolic-flux and network analysis in fourteen hemiascomycetous yeasts.

  FEMS yeast research 20050401

• NADPH-dependent metabolism of 17beta-estradiol and estrone to polar and nonpolar metabolites by human tissues and cytochrome P450 isoforms.

  Steroids 20050401

• Effective NADH-dependent oxidation of 7beta-hydroxy-delta8-tetrahydrocannabinol to the corresponding ketone by Japanese monkey hepatic microsomes.

  Biological & pharmaceutical bulletin 20050401

• Synthesis of novel amino and acetyl amino-4-methylcoumarins and evaluation of their antioxidant activity.

  European journal of medicinal chemistry 20050401

• Calcium/calmodulin-dependent nitric oxide synthase activity in the CNS of Aplysia californica: biochemical characterization and link to cGMP pathways.

  Journal of inorganic biochemistry 20050401

• Searching sequence space: two different approaches to dihydrofolate reductase catalysis.

  Chembiochem : a European journal of chemical biology 20050401

• Protective effects of ginseng saponins on 3-nitropropionic acid-induced striatal degeneration in rats.

  Neuropharmacology 20050401

• NAADP: a new second messenger comes of age.

  Molecular interventions 20050401

• The NAADP receptor: new receptors or new regulation?

  Molecular interventions 20050401

• Monitoring aerobic sludge digestion by online scanning fluorometry.

  Water research 20050401

• Levels of hexabromocyclododecane in harbor porpoises and common dolphins from western European seas, with evidence for stereoisomer-specific biotransformation by cytochrome p450.

  Environmental science & technology 20050401

• Detection and comparison of nitric oxide in clinically healthy horses and those with naturally acquired strangulating large colon volvulus.

  Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20050401

• Cellular defense against heat shock-induced oxidative damage by mitochondrial NADP+ -dependent isocitrate dehydrogenase.

  Free radical research 20050401

• Molecular cloning and characterization of a 1-deoxy-D-xylulose 5-phosphate reductoisomerase gene from Ginkgo biloba.

  DNA sequence : the journal of DNA sequencing and mapping 20050401

• A tryptophan that modulates tetrahydrobiopterin-dependent electron transfer in nitric oxide synthase regulates enzyme catalysis by additional mechanisms.

  Biochemistry 20050329

• Synthesis of arabinitol 1-phosphate and its use for characterization of arabinitol-phosphate dehydrogenase.

  Carbohydrate research 20050321

• Inhibition of Thermus thermophilus HB8 thioredoxin activity by platinum(II).

  Dalton transactions (Cambridge, England : 2003) 20050321

• Complete reversal of coenzyme specificity of xylitol dehydrogenase and increase of thermostability by the introduction of structural zinc.

  The Journal of biological chemistry 20050318

• Regulation of mitochondrial NADP+-dependent isocitrate dehydrogenase activity by glutathionylation.

  The Journal of biological chemistry 20050318

• Synthesis and fate of o-carboxybenzophenones in the biosynthesis of aflatoxin.

  Journal of the American Chemical Society 20050316

• Reduction of all-trans retinal to all-trans retinol in the outer segments of frog and mouse rod photoreceptors.

  Biophysical journal 20050301

• Repetitive transient depolarizations of the inner mitochondrial membrane induced by proton pumping.

  Biophysical journal 20050301

• Redox properties of the lipocalin alpha1-microglobulin: reduction of cytochrome c, hemoglobin, and free iron.

  Free radical biology & medicine 20050301

• N-methyl-L-amino acid dehydrogenase from Pseudomonas putida. A novel member of an unusual NAD(P)-dependent oxidoreductase superfamily.

  The FEBS journal 20050301

• Discovery and characterization of a Coenzyme A disulfide reductase from Pyrococcus horikoshii. Implications for this disulfide metabolism of anaerobic hyperthermophiles.

  The FEBS journal 20050301

• Characterization of cinnamyl alcohol dehydrogenase of Helicobacter pylori. An aldehyde dismutating enzyme.

  The FEBS journal 20050301

• Properties of the thermostable glutamate dehydrogenase of the mesophilic anaerobe Peptostreptoccus asaccharolyticus purified by a novel method after over-expression in an Escherichia coli host.

  FEMS microbiology letters 20050301

• Cerebral oxidative stress and depression of energy metabolism correlate with severity of diffuse brain injury in rats.

  Neurosurgery 20050301

• Increased NADPH concentration obtained by metabolic engineering of the pentose phosphate pathway in Aspergillus niger.

  The FEBS journal 20050301

• The stereoselective biotransformation of the anti-obesity drug sibutramine in rat liver microsomes and in primary cultures of rat hepatocytes.

  The Journal of pharmacy and pharmacology 20050301

• L-methionine reduces oxidant stress in endothelial cells: role of heme oxygenase-1, ferritin, and nitric oxide.

  The AAPS journal 20050301

• Glutathione metabolism is impaired in vitro by thallium(III) hydroxide.

  Toxicology 20050227

• The selective cause of an ancient adaptation.

  Science (New York, N.Y.) 20050225

• Role of methionine-13 in the catalytic mechanism of 6-phosphogluconate dehydrogenase from sheep liver.

  Biochemistry 20050222

• Nicotinic acid adenine dinucleotide phosphate potentiates neurite outgrowth.

  The Journal of biological chemistry 20050218

• The putative malate/lactate dehydrogenase from Pseudomonas putida is an NADPH-dependent delta1-piperideine-2-carboxylate/delta1-pyrroline-2-carboxylate reductase involved in the catabolism of D-lysine and D-proline.

  The Journal of biological chemistry 20050218

• Catalytic mechanism of Chlamydia trachomatis flavin-dependent thymidylate synthase.

  The Journal of biological chemistry 20050218

• Conformational diversity in NAD(H) and interacting transhydrogenase nicotinamide nucleotide binding domains.

  Journal of molecular biology 20050218

• Non-photochemical quenching of chlorophyll a fluorescence by oxidised plastoquinone: new evidences based on modulation of the redox state of the endogenous plastoquinone pool in broken spinach chloroplasts.

  Biochimica et biophysica acta 20050217

• Characterization of the polyene macrolide P450 epoxidase from Streptomyces natalensis that converts de-epoxypimaricin into pimaricin.

  The Biochemical journal 20050215

• Isoprenoid biosynthesis as a target for antibacterial and antiparasitic drugs: phosphonohydroxamic acids as inhibitors of deoxyxylulose phosphate reducto-isomerase.

  The Biochemical journal 20050215

• Cloning and characterization of antioxidant enzyme methionine sulfoxide-S-reductase from Caenorhabditis elegans.

  Archives of biochemistry and biophysics 20050215

• Reduced expression of the insulin receptor in mouse insulinoma (MIN6) cells reveals multiple roles of insulin signaling in gene expression, proliferation, insulin content, and secretion.

  The Journal of biological chemistry 20050211

• Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells.

  The Journal of biological chemistry 20050211

• Mitochondrial trans-2-enoyl-CoA reductase of wax ester fermentation from Euglena gracilis defines a new family of enzymes involved in lipid synthesis.

  The Journal of biological chemistry 20050211

• Kinetic properties and metabolic contributions of yeast mitochondrial and cytosolic NADP+-specific isocitrate dehydrogenases.

  The Journal of biological chemistry 20050211

• Effect of dietary high-oleic-acid oils that are rich in antioxidants on microsomal lipid peroxidation in rats.

  Journal of agricultural and food chemistry 20050209

• A novel NADPH:(bound) NADP+ reductase and NADH:(bound) NADP+ transhydrogenase function in bovine liver catalase.

  The Biochemical journal 20050201

• Endostatin uncouples NO and Ca2+ response to bradykinin through enhanced O2*- production in the intact coronary endothelium.

  American journal of physiology. Heart and circulatory physiology 20050201

• Malonate induces cell death via mitochondrial potential collapse and delayed swelling through an ROS-dependent pathway.

  British journal of pharmacology 20050201

• NADPH-consuming enzymes correlate with glucose-6-phosphate dehydrogenase in Purkinje cells: an immunohistochemical and enzyme histochemical study of the rat cerebellar cortex.

  Neuroscience research 20050201

• Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH.

  Acta crystallographica. Section D, Biological crystallography 20050201

• Protein expressed by the ho2 gene of the cyanobacterium Synechocystis sp. PCC 6803 is a true heme oxygenase. Properties of the heme and enzyme complex.

  The FEBS journal 20050201

• Properties of the recombinant glucose/galactose dehydrogenase from the extreme thermoacidophile, Picrophilus torridus.

  The FEBS journal 20050201

• Induction of cytotoxicity, aldehydic DNA lesions, and poly(ADP-ribose) polymerase-1 activation by catechol derivatives of pentachlorophenol in calf thymus DNA and in human breast cancer cells.

  Chemical research in toxicology 20050201

• Metabolic activation of a 1,3-disubstituted piperazine derivative: evidence for a novel ring contraction to an imidazoline.

  Chemical research in toxicology 20050201

• Indole hydroxylation by bacterial cytochrome P450 BM-3 and modulation of activity by cumene hydroperoxide.

  Bioscience, biotechnology, and biochemistry 20050201

• Purification and characterization of NADPH-dependent Cr(VI) reductase from Escherichia coli ATCC 33456.

  Journal of microbiology (Seoul, Korea) 20050201

• Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274-->Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+ and NADP+.

  FEBS letters 20050131

• Regiospecificity determinants of human heme oxygenase: differential NADPH- and ascorbate-dependent heme cleavage by the R183E mutant.

  The Journal of biological chemistry 20050128

• Roles of distal Asp in heme oxygenase from Corynebacterium diphtheriae, HmuO: A water-driven oxygen activation mechanism.

  The Journal of biological chemistry 20050128

• Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability.

  Journal of molecular biology 20050121

• Non-invasive live-cell measurement of changes in macrophage NAD(P)H by two-photon microscopy.

  Immunology letters 20050115

• Estimating the number of viable animal cells in multiwell culture--a tetrazolium-based assay.

  Analytical biochemistry 20050115

• A design of fluorescent probes for superoxide based on a nonredox mechanism.

  Journal of the American Chemical Society 20050112

• Redox potential and equilibria in the reductive half-reaction of Vibrio harveyi NADPH-FMN oxidoreductase.

  Biochemistry 20050111

• Involvement of NADPH in the interaction between heme oxygenase-1 and cytochrome P450 reductase.

  The Journal of biological chemistry 20050107

• Sulfonylurea as well as elevated glucose levels stimulate reactive oxygen species production in the pancreatic beta-cell line, MIN6-a role of NAD(P)H oxidase in beta-cells.

  Biochemical and biophysical research communications 20050107

• The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation.

  Journal of molecular biology 20050107

• The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography.

  The Biochemical journal 20050101

• Cytosolic NADPH may regulate differences in basal Nox oxidase-derived superoxide generation in bovine coronary and pulmonary arteries.

  American journal of physiology. Heart and circulatory physiology 20050101

• Characterization and modulation by drugs of sheep liver microsomal flavin monooxygenase activity.

  Cell biochemistry and function 20050101

• Plasticity in light reactions of photosynthesis for energy production and photoprotection.

  Journal of experimental botany 20050101

• Prostaglandin F2alpha potentiates the calcium dependent activation of mitochondrial metabolism in luteal cells.

  Cell calcium 20050101

• Role of the nicotinic acid group in NAADP receptor selectivity.

  Cell calcium 20050101

• Peroxide detoxification by brain cells.

  Journal of neuroscience research 20050101

• Structure--function studies on the iron-sulfur flavoenzyme glutamate synthase: an unexpectedly complex self-regulated enzyme.

  Archives of biochemistry and biophysics 20050101

• Protein dynamics and electrostatics in the function of p-hydroxybenzoate hydroxylase.

  Archives of biochemistry and biophysics 20050101

• Insulin enhances mitochondrial inner membrane potential and increases ATP levels through phosphoinositide 3-kinase in adult sensory neurons.

  Molecular and cellular neurosciences 20050101

• Uncoupling of nutrient metabolism from insulin secretion by overexpression of cytosolic phospholipase A(2).

  Diabetes 20050101

• Inhibition of Nox-4 activity by plumbagin, a plant-derived bioactive naphthoquinone.

  The Journal of pharmacy and pharmacology 20050101

• Impact of sperm morphology on DNA damage caused by oxidative stress induced by beta-nicotinamide adenine dinucleotide phosphate.

  Fertility and sterility 20050101

• Probing the mechanism of the bifunctional enzyme ketol-acid reductoisomerase by site-directed mutagenesis of the active site.

  The FEBS journal 20050101

• Electron transfer ability from NADH to menaquinone and from NADPH to oxygen of type II NADH dehydrogenase of Corynebacterium glutamicum.

  Bioscience, biotechnology, and biochemistry 20050101

• Asymmetric reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate with two co-existing, recombinant Escherichia coli strains.

  Biotechnology letters 20050101

• Unipolar brush cells--a new type of excitatory interneuron in the cerebellar cortex and cochlear nuclei of the brainstem.

  Neuroscience and behavioral physiology 20050101

• Inhibitory effects of flavonoids on the reduction of progesterone to 20alpha-hydroxyprogesterone in rat liver.

  The Journal of steroid biochemistry and molecular biology 20050101

• Oxidative stress and phytochelatin characterisation in bread wheat exposed to cadmium excess.

  Plant physiology and biochemistry : PPB 20050101

• Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes.

  Malaria journal 20050101

• Redox regulation: a broadening horizon.

  Annual review of plant biology 20050101

• Titration of E. coli transhydrogenase domain III with bound NADP+ or NADPH studied by NMR reveals no pH-dependent conformational change in the physiological pH range.

  Biochimica et biophysica acta 20050101

• Oxalomalate, a competitive inhibitor of NADP+ -dependent isocitrate dehydrogenase, regulates lipid peroxidation-mediated apoptosis in U937 cells.

  Free radical research 20050101

• Adenosine 2'-monophosphate, 5'-O-[S-(4-succinimidylbenzophenone)-thiophosphate]: a new photoaffinity label for the coenzyme site of porcine NADP-specific isocitrate dehydrogenase.

  Bioconjugate chemistry 20050101

• Involvement of mitochondrial potential and calcium buffering capacity in minocycline cytoprotective actions.

  Neuroscience 20050101

• Enzymatic redox cofactor regeneration in organic media: functionalization and application of glycerol dehydrogenase and soluble transhydrogenase in reverse micelles.

  Biotechnology progress 20050101

• NAADP receptors.

  Cell calcium 20050101

• Band 3 tyr-phosphorylation in normal and glucose-6-phospate dehydrogenase-deficient human erythrocytes.

  Molecular membrane biology 20050101

• Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility.

  Reproductive biology and endocrinology : RB&E 20050101

• The effects of alpha-lipoic acid on nitric oxide synthetase dispersion in penile function in streptozotocin-induced diabetic rats.

  International journal of tissue reactions 20050101

• Effects of etodolac on P450 isoform-specific activities in human hepatic microsomes.

  Arzneimittel-Forschung 20050101

• The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells.

  The Journal of biological chemistry 20041231

• Conformational changes in the active site loops of dihydrofolate reductase during the catalytic cycle.

  Biochemistry 20041228

• Lysosome-sarcoplasmic reticulum junctions. A trigger zone for calcium signaling by nicotinic acid adenine dinucleotide phosphate and endothelin-1.

  The Journal of biological chemistry 20041224

• Mitochondrial activation and the pyruvate paradox in a human cell line.

  FEBS letters 20041217

• Cell biology. Oxygen sensing: it's a gas!

  Science (New York, N.Y.) 20041217

• Farnesol is glucuronidated in human liver, kidney and intestine in vitro, and is a novel substrate for UGT2B7 and UGT1A1.

  The Biochemical journal 20041215

• Aluminum decreases the glutathione regeneration by the inhibition of NADP-isocitrate dehydrogenase in mitochondria.

  Journal of cellular biochemistry 20041215

• The antioxidant defense protein heme oxygenase 1 is a novel target for statins in endothelial cells.

  Free radical biology & medicine 20041215

• Immobilized cofactor derivatives for kinetic-based enzyme capture strategies: direct coupling of NAD(P)+.

  Analytical biochemistry 20041215

• Glutathione-dependent reduction of arsenate in human erythrocytes--a process independent of purine nucleoside phosphorylase.

  Toxicological sciences : an official journal of the Society of Toxicology 20041201

• NAADP triggers the fertilization potential in starfish oocytes.

  Cell calcium 20041201

• Indirect electrochemical reduction of nicotinamide coenzymes.

  Bioelectrochemistry (Amsterdam, Netherlands) 20041201

• Bacterial redox sensors.

  Nature reviews. Microbiology 20041201

• Structural and functional analysis of the gpsA gene product of Archaeoglobus fulgidus: a glycerol-3-phosphate dehydrogenase with an unusual NADP+ preference.

  Protein science : a publication of the Protein Society 20041201

• Method for isolating tight-binding inhibitors of rat lens aldose reductase.

  Experimental eye research 20041201

• Purine nucleotides and their metabolites in erythrocytes of streptozotocin diabetic rats.

  Diabetes & metabolism 20041201

• Flavin-containing monooxygenase activity in camel tissues: comparison with rat and human liver enzymes.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20041201

• Conversion ratio of tryptophan to niacin in Japanese women fed a purified diet conforming to the Japanese Dietary Reference Intakes.

  Journal of nutritional science and vitaminology 20041201

• Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity.

  Biochemistry 20041123

• FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane.

  The Journal of biological chemistry 20041119

• The human FA2H gene encodes a fatty acid 2-hydroxylase.

  The Journal of biological chemistry 20041119

• Mechanism to study 1:1 stoichiometry of NADPH and alkoxyphenoxazones metabolism spectrophotometrically in subcellular biological preparations.

  Biochimica et biophysica acta 20041118

• Assay and subcellular localization of pyrroline-5-carboxylate dehydrogenase in rat liver.

  Biochimica et biophysica acta 20041118

• The novel pathway for ketodiene oxylipin biosynthesis in Jerusalem artichoke (Helianthus tuberosus) tubers.

  Biochimica et biophysica acta 20041108

• Role of Lys-32 residues in R67 dihydrofolate reductase probed by asymmetric mutations.

  The Journal of biological chemistry 20041105

• 'Catch 222,' the effects of symmetry on ligand binding and catalysis in R67 dihydrofolate reductase as determined by mutations at Tyr-69.

  The Journal of biological chemistry 20041105

• Consumption of nitric oxide by endothelial cells: evidence for the involvement of a NAD(P)H-, flavin- and heme-dependent dioxygenase reaction.

  FEBS letters 20041105

• Decreased cardiac mitochondrial NADP+-isocitrate dehydrogenase activity and expression: a marker of oxidative stress in hypertrophy development.

  American journal of physiology. Heart and circulatory physiology 20041101

• Ca2+ release via ryanodine receptors and Ca2+ entry: major mechanisms in NAADP-mediated Ca2+ signaling in T-lymphocytes.

  Cellular signalling 20041101

• The rat liver peroxisomal membrane forms a permeability barrier for cofactors but not for small metabolites in vitro.

  Journal of cell science 20041101

• Exploiting thiol modifications.

  PLoS biology 20041101

• Inhibition of pea ferredoxin-NADP(H) reductase by Zn-ferrocyanide.

  European journal of biochemistry 20041101

• Photosynthetic response of transgenic soybean plants, containing an Arabidopsis P5CR gene, during heat and drought stress.

  Journal of plant physiology 20041101

• Anaphylatoxin signaling in human neutrophils. A key role for sphingosine kinase.

  The Journal of biological chemistry 20041022

• The human TAZ gene complements mitochondrial dysfunction in the yeast taz1Delta mutant. Implications for Barth syndrome.

  The Journal of biological chemistry 20041022

• Alternative nitric oxide-producing substrates for NO synthases.

  Free radical biology & medicine 20041015

• Development of an amperometric biosensing method for the determination of L-fucose in pretreated urine.

  Biosensors & bioelectronics 20041015

• Redox modulation of tau and microtubule-associated protein-2 by the glutathione/glutaredoxin reductase system.

  Biochemical and biophysical research communications 20041008

• Crystal structure and kinetics identify Escherichia coli YdcW gene product as a medium-chain aldehyde dehydrogenase.

  Journal of molecular biology 20041008

• Salt-dependent studies of NADP-dependent isocitrate dehydrogenase from the halophilic archaeon Haloferax volcanii.

  Extremophiles : life under extreme conditions 20041001

• Iodotyrosine dehalogenase 1 (DEHAL1) is a transmembrane protein involved in the recycling of iodide close to the thyroglobulin iodination site.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041001

• Exogenous NADPH increases cerebral blood flow through NADPH oxidase-dependent and -independent mechanisms.

  Arteriosclerosis, thrombosis, and vascular biology 20041001

• Biosynthesis of [3H]7 alpha-hydroxy-, 7 beta-hydroxy-, and 7-oxo-dehydroepiandrosterone using pig liver microsomal fractions.

  Analytical biochemistry 20041001

• Respiratory properties and malate metabolism in Percoll-purified mitochondria isolated from pineapple, Ananas comosus (L.) Merr. cv. smooth cayenne.

  Journal of experimental botany 20041001

• Structural insights into the neuroprotective-acting carbonyl reductase Sniffer of Drosophila melanogaster.

  Journal of molecular biology 20041001

• Testosterone 1 beta-hydroxylation by human cytochrome P450 3A4.

  European journal of biochemistry 20041001

• Determination of piceatannol in rat serum and liver microsomes: pharmacokinetics and phase I and II biotransformation.

  Biomedical chromatography : BMC 20041001

• Inhibition of Leishmania major pteridine reductase by 2,4,6-triaminoquinazoline: structure of the NADPH ternary complex.

  Acta crystallographica. Section D, Biological crystallography 20041001

• New enzymes involved in aerobic benzoate metabolism in Azoarcus evansii.

  Molecular microbiology 20041001

• 11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response.

  Endocrine reviews 20041001

• In vitro confirmation of selegiline N-oxidation by flavin-containing monooxygenase in rat microsome using LC-ESI MS.

  Biological & pharmaceutical bulletin 20041001

• Autofluorescence properties of isolated rat hepatocytes under different metabolic conditions.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20041001

• Human sperm superoxide anion generation and correlation with semen quality in patients with male infertility.

  Fertility and sterility 20041001

• Manipulation of malic enzyme in Saccharomyces cerevisiae for increasing NADPH production capacity aerobically in different cellular compartments.

  Metabolic engineering 20041001

• Genome-wide analysis of Kluyveromyces lactis in wild-type and rag2 mutant strains.

  Genome 20041001

• Cloning and enhanced expression of the cytochrome P450nor gene (nicA; CYP55A5) encoding nitric oxide reductase from Aspergillus oryzae.

  Bioscience, biotechnology, and biochemistry 20041001

• Non-enzymatic and enzymatic lipid peroxidation of microsomes and nuclei obtained from rat liver.

  Molecular and cellular biochemistry 20041001

• Phosphoinositide metabolism at fertilization of sea urchin eggs measured with a GFP-probe.

  Development, growth & differentiation 20041001

• [Effect of osmoregulation on the plasma membrane redox activity in chilling injury sensitive soybean seeds].

  Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20041001

• Dissection of the physiological interconversion of 5alpha-DHT and 3alpha-diol by rat 3alpha-HSD via transient kinetics shows that the chemical step is rate-determining: effect of mutating cofactor and substrate-binding pocket residues on catalysis.

  Biochemistry 20040928

• Bifunctional catalysis by CDP-ribitol synthase: convergent recruitment of reductase and cytidylyltransferase activities in Haemophilus influenzae and Staphylococcus aureus.

  Biochemistry 20040921

• Photoinduced production of NAD(P)H from an activated fluorescein-DNA monolayer.

  Chemical communications (Cambridge, England) 20040921

• Cytosolic NADP+-dependent isocitrate dehydrogenase plays a key role in lipid metabolism.

  The Journal of biological chemistry 20040917

• Characterization of NADP-dependent malic enzyme from developing castor oil seed endosperm.

  Archives of biochemistry and biophysics 20040915

• Fluorescent intensity of a novel NADPH-binding protein of Vibrio vulnificus can be improved by directed evolution.

  Biochemical and biophysical research communications 20040910

• Crystal structure of E.coli alcohol dehydrogenase YqhD: evidence of a covalently modified NADP coenzyme.

  Journal of molecular biology 20040910

• Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908

• Studies on the interaction of NADPH with Rhodobacter sphaeroides biotin sulfoxide reductase.

  Biochemistry 20040907

• Bioconversion of 3beta-hydroxy-5-cholenoic acid into chenodeoxycholic acid by rat brain enzyme systems.

  Journal of lipid research 20040901

• Human neutrophils synthesize IL-8 in an IgE-mediated activation.

  Journal of leukocyte biology 20040901

• Mitochondrial permeability transition in neuronal damage promoted by Ca2+ and respiratory chain complex II inhibition.

  Journal of neurochemistry 20040901

• Identification of an N-methyl-4-phenylpyridinium-like metabolite of the antidiarrheal agent loperamide in human liver microsomes: underlying reason(s) for the lack of neurotoxicity despite the bioactivation event.

  Drug metabolism and disposition: the biological fate of chemicals 20040901

• Strain differences in diazepam metabolism at its three metabolic sites in sprague-dawley, brown norway, dark agouti, and wistar strain rats.

  Drug metabolism and disposition: the biological fate of chemicals 20040901

• In vitro metabolism of MK-0767 [(+/-)-5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[(4-trifluoromethyl) phenyl]methyl]benzamide], a peroxisome proliferator-activated receptor alpha/gamma agonist. I. Role of cytochrome P450, methyltransferases, flavin monooxygenases, and esterases.

  Drug metabolism and disposition: the biological fate of chemicals 20040901

• In vitro metabolism of MK-0767 [(+/-)-5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[(4-trifluoromethyl)-phenyl] methyl]benzamide], a peroxisome proliferator-activated receptor alpha/gamma agonist. II. Identification of metabolites by liquid chromatography-tandem mass spectrometry.

  Drug metabolism and disposition: the biological fate of chemicals 20040901

• AraPerox. A database of putative Arabidopsis proteins from plant peroxisomes.

  Plant physiology 20040901

• A thermostable shikimate 5-dehydrogenase from the archaeon Archaeoglobus fulgidus.

  FEMS microbiology letters 20040901

• Induction and functional analysis of two reduced nicotinamide adenine dinucleotide phosphate-dependent glutathione peroxidase-like proteins in Synechocystis PCC 6803 during the progression of oxidative stress.

  Plant physiology 20040901

• Dietary lipid content influences the activity of lipogenic enzymes in the liver and on whole body delta13C values of Nile tilapia, Oreochromis niloticus (L.).

  Isotopes in environmental and health studies 20040901

• Effect of lead ions on rat erythrocyte purine content.

  Biological trace element research 20040901

• Role of zinc on lipid peroxidation and antioxidative enzymes in intestines of ethanol-fed rats.

  Biological trace element research 20040901

• Autofluorescence lifetime imaging of cultivated cells using a UV picosecond laser diode.

  Journal of fluorescence 20040901

• In vitro interactions of thallium with components of the glutathione-dependent antioxidant defence system.

  Free radical research 20040901

• Oxidation and rearrangements of flavanones by mammalian cytochrome P450.

  Xenobiotica; the fate of foreign compounds in biological systems 20040901

• Metabolism of human cytochrome P450 marker substrates in mouse: a strain and gender comparison.

  Xenobiotica; the fate of foreign compounds in biological systems 20040901

• Active-site conformational changes associated with hydride transfer in proton-translocating transhydrogenase.

  Biochemistry 20040831

• Redox properties of the isolated flavin mononucleotide- and flavin adenine dinucleotide-binding domains of neuronal nitric oxide synthase.

  Biochemistry 20040831

• The FAD-shielding residue Phe1395 regulates neuronal nitric-oxide synthase catalysis by controlling NADP+ affinity and a conformational equilibrium within the flavoprotein domain.

  The Journal of biological chemistry 20040820

• Apo and Holo structures of an NADPH-dependent cinnamyl alcohol dehydrogenase from Saccharomyces cerevisiae.

  Journal of molecular biology 20040820

• Mechanistic studies of a flavin-dependent thymidylate synthase.

  Biochemistry 20040817

• Characterization of the beta-carbon processing reactions of the mammalian cytosolic fatty acid synthase: role of the central core.

  Biochemistry 20040817

• Crystal structure of a putative NADPH-dependent oxidoreductase (GI: 18204011) from mouse at 2.10 A resolution.

  Proteins 20040815

• Stripping down the mitochondrial cholesterol hydroxylase system, a kinetics study.

  The Journal of biological chemistry 20040813

• Crystal structure and functional characterization of yeast YLR011wp, an enzyme with NAD(P)H-FMN and ferric iron reductase activities.

  The Journal of biological chemistry 20040813

• Structural Basis of allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde 3-Phosphate dehydrogenase from Thermoproteus tenax.

  Journal of molecular biology 20040813

• Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity.

  The Journal of biological chemistry 20040806

• A metabolic model describing the H2O2 elimination by mammalian cells including H2O2 permeation through cytoplasmic and peroxisomal membranes: comparison with experimental data.

  Biochimica et biophysica acta 20040804

• High-level production and optimization of monodispersity of 11beta-hydroxysteroid dehydrogenase type 1.

  Biochimica et biophysica acta 20040802

• Towards a structural classification of phosphate binding sites in protein-nucleotide complexes: an automated all-against-all structural comparison using geometric matching.

  Proteins 20040801

• NADPH-dependent formation of polar and nonpolar estrogen metabolites following incubations of 17 beta-estradiol with human liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20040801

• Triazine dyes are agonists of the NAADP receptor.

  British journal of pharmacology 20040801

• The NAADP receptor: commentary on Billington et al.

  British journal of pharmacology 20040801

• Metabolism of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine by Clostridium bifermentans strain HAW-1 and several other H2-producing fermentative anaerobic bacteria.

  FEMS microbiology letters 20040801

• The crystallographic structure of the aldose reductase-IDD552 complex shows direct proton donation from tyrosine 48.

  Acta crystallographica. Section D, Biological crystallography 20040801

• Thermostable flavin reductase that couples with dibenzothiophene monooxygenase, from thermophilic Bacillus sp. DSM411: purification, characterization, and gene cloning.

  Bioscience, biotechnology, and biochemistry 20040801

• Pyruvate phosphate dikinase and pyrophosphate metabolism in the glycosome of Trypanosoma cruzi epimastigotes.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20040801

• [2,4-Dienoyl-CoA reductases: from discovery toward pathophysiological significance].

  Nihon rinsho. Japanese journal of clinical medicine 20040801

• Chemiluminescence: comparison of whole blood with isolated polymorphonuclear leukocytes after major trauma.

  The Journal of trauma 20040801

• Calcium and fertilization: the beginning of life.

  Trends in biochemical sciences 20040801

• Inactivation of NADP(+)-dependent isocitrate dehydrogenase by singlet oxygen derived from photoactivated rose bengal.

  Biochimie 20040801

• [Glucose 6-phosphate dehydrogenase deficiency: a protection against malaria and a risk for hemolytic accidents].

  Comptes rendus biologies 20040801

• Comparative inhibition of inducible and constitutive CYPs in rat hepatic microsomes by parathion.

  Xenobiotica; the fate of foreign compounds in biological systems 20040801

• The myenteric plexus of the rat colon after fecal stream diversion: a morpho-quantitative study.

  Autonomic neuroscience : basic & clinical 20040730

• Quantitative NAD(P)H/flavoprotein autofluorescence imaging reveals metabolic mechanisms of pancreatic islet pyruvate response.

  The Journal of biological chemistry 20040723

• Coenzyme site-directed mutants of photosynthetic A4-GAPDH show selectively reduced NADPH-dependent catalysis, similar to regulatory AB-GAPDH inhibited by oxidized thioredoxin.

  Journal of molecular biology 20040723

• Protection of tamoxifen against oxidation of mitochondrial thiols and NAD(P)H underlying the permeability transition induced by prooxidants.

  Chemico-biological interactions 20040720

• Direct determination of vibrational density of states change on ligand binding to a protein.

  Physical review letters 20040709

• Subunit composition of NDH-1 complexes of Synechocystis sp. PCC 6803: identification of two new ndh gene products with nuclear-encoded homologues in the chloroplast Ndh complex.

  The Journal of biological chemistry 20040702

• Identification of cytochrome P450-reductase as the enzyme responsible for NADPH-dependent lucigenin and tetrazolium salt reduction in rat epididymal sperm preparations.

  Biology of reproduction 20040701

• Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues.

  Molecular endocrinology (Baltimore, Md.) 20040701

• Omega-hydroxylation of phytanic acid in rat liver microsomes: implications for Refsum disease.

  Journal of lipid research 20040701

• Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040701

• Androgen secretion by Rcho-1 cells is independent of extracellular glutamate concentration.

  Placenta 20040701

• Overexpression, purification, and characterization of ATP-NAD kinase of Sphingomonas sp. A1.

  Protein expression and purification 20040701

• New aspects of nuclear calcium signalling.

  Journal of cell science 20040701

• Dynamic flexibility in the light reactions of photosynthesis governed by both electron and proton transfer reactions.

  Trends in plant science 20040701

• Involvement of oxidative stress in the profibrotic action of aldosterone. Interaction wtih the renin-angiotension system.

  American journal of hypertension 20040701

• Functional analysis of the ALD gene family of Saccharomyces cerevisiae during anaerobic growth on glucose: the NADP+-dependent Ald6p and Ald5p isoforms play a major role in acetate formation.

  Microbiology (Reading, England) 20040701

• Neurochemistry of the gustatory subgemmal plexus.

  Chemical senses 20040701

• Cell type-dependent release of nitric oxide and/or reactive nitrogenoxide species from intracellular SIN-1: effects on cellular NAD(P)H.

  Biological chemistry 20040701

• Purification and characterization of glucose-6-phosphate dehydrogenase from rat small intestine.

  The protein journal 20040701

• CDNA cloning of a short isoform of human liver NADP (H) -dependent retinol dehydrogenase/reductase and analysis of its characteristics.

  Yi chuan xue bao = Acta genetica Sinica 20040701

• Effect of angiotensin II on energetics, glucose metabolism and cytosolic NADH/NAD and NADPH/NADP redox in vascular smooth muscle.

  Molecular and cellular biochemistry 20040701

• [Sequencing and bioinformatic analysis of NRDRiso cDNA].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040701

• Identification and characterization of the product release steps within the catalytic cycle of protochlorophyllide oxidoreductase.

  Biochemistry 20040629

• Bright fluorescence of a novel protein from Vibrio vulnificus depends on NADPH and the expression of this protein is regulated by a LysR-type regulatory gene.

  Biochemical and biophysical research communications 20040618

• Decrease in arterial pressure induced by adrenomedullin in the hypothalamic paraventricular nucleus is mediated by nitric oxide and GABA.

  Regulatory peptides 20040615

• Defining the binding site of homotetrameric R67 dihydrofolate reductase and correlating binding enthalpy with catalysis.

  Biochemistry 20040615

• Characterization of Mycobacterium tuberculosis NAD kinase: functional analysis of the full-length enzyme by site-directed mutagenesis.

  Biochemistry 20040615

• Glutathione content and adaptation to endogenously induced energy depletion in Mv1Lu cells.

  Free radical biology & medicine 20040615

• Inhibition of human P450 enzymes by multiple constituents of the Ginkgo biloba extract.

  Biochemical and biophysical research communications 20040611

• Cell surface oxygen consumption by mitochondrial gene knockout cells.

  Biochimica et biophysica acta 20040607

• Oxidation of thioredoxin reductase in HeLa cells stimulated with tumor necrosis factor-alpha.

  FEBS letters 20040604

• Cyclic electron flow around photosystem I is essential for photosynthesis.

  Nature 20040603

• Reduction and uptake of methylene blue by human erythrocytes.

  American journal of physiology. Cell physiology 20040601

• CO2 enhanced peroxidase activity of SOD1: the effects of pH.

  Free radical biology & medicine 20040601

• Identifying determinants of NADPH specificity in Baeyer-Villiger monooxygenases.

  European journal of biochemistry 20040601

• Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases.

  Drug metabolism and disposition: the biological fate of chemicals 20040601

• Transmembrane electron transport in sealed and NAD(P)H-loaded right-side-out plasma membrane vesicles isolated from maize (Zea mays L.) roots.

  Journal of experimental botany 20040601

• Race-specific differences in endothelial function: predisposition of African Americans to vascular diseases.

  Circulation 20040601

• Comparative kinetic characterization of rat thyroid iodotyrosine dehalogenase and iodothyronine deiodinase type 1.

  The Journal of endocrinology 20040601

• Extracellular 3beta-hydroxysteroid oxidase of Mycobacterium vaccae VKM Ac-1815D.

  The Journal of steroid biochemistry and molecular biology 20040601

• Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop.

  The Journal of biological chemistry 20040521

• Fcgamma RI-triggered generation of arachidonic acid and eicosanoids requires iPLA2 but not cPLA2 in human monocytic cells.

  The Journal of biological chemistry 20040521

• Loop relaxation, a mechanism that explains the reduced specificity of rabbit 20alpha-hydroxysteroid dehydrogenase, a member of the aldo-keto reductase superfamily.

  Journal of molecular biology 20040521

• Alanine scanning mutagenesis of the testosterone binding site of rat 3 alpha-hydroxysteroid dehydrogenase demonstrates contact residues influence the rate-determining step.

  Biochemistry 20040518

• Oxidation and reduction of pyridine nucleotides in alamethicin-permeabilized plant mitochondria.

  The Biochemical journal 20040515

• Crystal structure of human L-xylulose reductase holoenzyme: probing the role of Asn107 with site-directed mutagenesis.

  Proteins 20040515

• Human mitochondrial thioredoxin reductase reduces cytochrome c and confers resistance to complex III inhibition.

  Free radical biology & medicine 20040515

• 6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase form a supramolecular complex in human neutrophils that undergoes retrograde trafficking during pregnancy.

  Journal of immunology (Baltimore, Md. : 1950) 20040515

• Conversion of the 2,2,6,6-tetramethylpiperidine moiety to a 2,2-dimethylpyrrolidine by cytochrome P450: evidence for a mechanism involving nitroxide radicals and heme iron.

  Biochemistry 20040511

• Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium.

  Biochemistry 20040511

• Use of an ionic liquid in a two-phase system to improve an alcohol dehydrogenase catalysed reduction.

  Chemical communications (Cambridge, England) 20040507

• Morphology-associated expression of NADP-dependent glutamate dehydrogenases during yeast-mycelium transition of a dimorphic fungus Benjaminiella poitrasii.

  Antonie van Leeuwenhoek 20040501

• Chromogenic derivatives of AHTN (6-acetyl-1,1,2,4,4,7-hexamethyltetralin) react with amino acids and protein in vitro. Spectral characteristics of the colour products.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040501

• Reductive activation of ricin and ricin A-chain immunotoxins by protein disulfide isomerase and thioredoxin reductase.

  Biochemical pharmacology 20040501

• Transient-phase kinetic studies on the nucleotide binding to 3alpha-hydroxysteroid dehydrogenase from Pseudomonas sp. B-0831 using fluorescence stopped-flow procedures.

  European journal of biochemistry 20040501

• Characterization of striatal cultures with the effect of QUIN and NMDA.

  Neuroscience research 20040501

• Inositol 1,4,5-trisphosphate and its co-players in the concert of Ca2+ signalling--new faces in the line up.

  Current molecular medicine 20040501

• Regulation of uterine function: a biochemical conundrum in the regulation of smooth muscle relaxation.

  Molecular pharmacology 20040501

• Insulin generates free radicals by an NAD(P)H, phosphatidylinositol 3'-kinase-dependent mechanism in human skin fibroblasts ex vivo.

  Diabetes 20040501

• A sensitive enzymatic assay for the determination of sucrose in serum and urine.

  Clinica chimica acta; international journal of clinical chemistry 20040501

• NQO1 activity in the main and the accessory olfactory systems correlates with the zonal topography of projection maps.

  The European journal of neuroscience 20040501

• Functional constraints of alcohol dehydrogenase (ADH) of tephritidae and relationships with other Dipteran species.

  Journal of molecular evolution 20040501

• A conserved aspartate (Asp-1393) regulates NADPH reduction of neuronal nitric-oxide synthase: implications for catalysis.

  The Journal of biological chemistry 20040430

• Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity.

  The Journal of biological chemistry 20040423

• The catalytic and kinetic mechanisms of NADPH-dependent alkenal/one oxidoreductase.

  The Journal of biological chemistry 20040423

• Kinetic and chemical mechanism of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate isomeroreductase.

  Biochemistry 20040413

• Human erythrocyte recycling of ascorbic acid: relative contributions from the ascorbate free radical and dehydroascorbic acid.

  The Journal of biological chemistry 20040409

• Crystal structure of 1-deoxy-d-xylulose-5-phosphate reductoisomerase from Zymomonas mobilis at 1.9-A resolution.

  Biochimica et biophysica acta 20040408

• An appraisal of multiple NADPH binding-site models proposed for cytochrome P450 reductase, NO synthase, and related diflavin reductase systems.

  Biochemistry 20040406

• Evaluation of xenobiotic N- and S-oxidation by variant flavin-containing monooxygenase 1 (FMO1) enzymes.

  Toxicological sciences : an official journal of the Society of Toxicology 20040401

• Molecular cloning, overexpression, purification, and characterization of an aerobic FMN-dependent azoreductase from Enterococcus faecalis.

  Protein expression and purification 20040401

• Characterization, crystallization and preliminary X-ray analysis of bifunctional dihydrofolate reductase-thymidylate synthase from Plasmodium falciparum.

  Acta crystallographica. Section D, Biological crystallography 20040401

• Complement-independent Ab-induced peroxide lysis of platelets requires 12-lipoxygenase and a platelet NADPH oxidase pathway.

  The Journal of clinical investigation 20040401

• Polyol accumulation by Aspergillus oryzae at low water activity in solid-state fermentation.

  Microbiology (Reading, England) 20040401

• Kaurenolides and fujenoic acids are side products of the gibberellin P450-1 monooxygenase in Gibberella fujikuroi.

  Phytochemistry 20040401

• Adjustments of the enzymatic complement for polyol biosynthesis and accumulation in diapausing cold-acclimated adults of Pyrrhocoris apterus.

  Journal of insect physiology 20040401

• Formation and reduction of aryl and heterocyclic nitroso compounds and significance in the flux of hydroxylamines.

  Chemical research in toxicology 20040401

• Involvement of NADPH oxidase in hydrogen peroxide accumulation by Aspergillus niger elicitor-induced Taxus chinensis cell cultures.

  Journal of plant physiology 20040401

• 3alpha/beta,20beta-hydroxysteroid dehydrogenase (porcine testicular carbonyl reductase) also has a cysteine residue that is involved in binding of cofactor NADPH.

  The Journal of steroid biochemistry and molecular biology 20040401

• [Cloning and analysis of NADP(H) -dependent retinol dehydrogenase/reductase gene: a novel member of short-chain dehydrogenase/reductase].

  Yi chuan xue bao = Acta genetica Sinica 20040401

• The effect of cimetidine on dextromethorphan O-demethylase activity of human liver microsomes and recombinant CYP2D6.

  Drug metabolism and disposition: the biological fate of chemicals 20040401

• Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines.

  The Journal of biological chemistry 20040326

• Oxidative DNA damage induced by nitrotyrosine, a biomarker of inflammation.

  Biochemical and biophysical research communications 20040326

• Structural and catalytic diversity in the two family 11 aldo-keto reductases.

  Journal of molecular biology 20040326

• Influence of compartmental localization on the function of yeast NADP+-specific isocitrate dehydrogenases.

  Archives of biochemistry and biophysics 20040315

• Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine.

  Archives of biochemistry and biophysics 20040315

• Tracking variations in nicotinamide cofactors extracted from cultured cells using capillary electrophoresis with multiphoton excitation of fluorescence.

  Analytical biochemistry 20040315

• NADPH dependent activation of microsomal glutathione transferase 1.

  Chemico-biological interactions 20040315

• Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action.

  The Journal of biological chemistry 20040312

• Spectroscopic and chromatographic evidences of NADPH in human placental extract used as wound healer.

  Journal of pharmaceutical and biomedical analysis 20040310

• New tools for molecular imaging of redox metabolism: development of a fluorogenic probe for 3 alpha-hydroxysteroid dehydrogenases.

  Journal of the American Chemical Society 20040303

• Crystal structure of human prostaglandin F synthase (AKR1C3).

  Biochemistry 20040302

• Biotransformation of glucose to 5-keto-D-gluconic acid by recombinant Gluconobacter oxydans DSM 2343.

  Applied microbiology and biotechnology 20040301

• Developmental changes in nitric oxide synthesis in the ovine placenta.

  Biology of reproduction 20040301

• Application of the measurement of oxidized pyridine dinucleotides with high-performance liquid chromatography-fluorescence detection to assay the uncoupled oxidation of NADPH by neuronal nitric oxide synthase.

  Analytical biochemistry 20040301

• Impact of incubation conditions on bufuralol human clearance predictions: enzyme lability and nonspecific binding.

  Drug metabolism and disposition: the biological fate of chemicals 20040301

• Glucose-6-phosphate dehydrogenase-deficient cells show an increased propensity for oxidant-induced senescence.

  Free radical biology & medicine 20040301

• Cyp1a2 protects against reactive oxygen production in mouse liver microsomes.

  Free radical biology & medicine 20040301

• Uncoupling-mediated generation of reactive oxygen by halogenated aromatic hydrocarbons in mouse liver microsomes.

  Free radical biology & medicine 20040301

• The new life of a centenarian: signalling functions of NAD(P).

  Trends in biochemical sciences 20040301

• Type 2 isopentenyl diphosphate isomerase from a thermoacidophilic archaeon Sulfolobus shibatae.

  European journal of biochemistry 20040301

• Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia-telangiectasia.

  Journal of neurochemistry 20040301

• Cofactor-induced conformational rearrangements establish a catalytically competent active site and a proton relay conduit in FabG.

  Structure (London, England : 1993) 20040301

• Cytochrome P450-catalyzed brassinosteroid pathway activation through synthesis of castasterone and brassinolide in Phaseolus vulgaris.

  Phytochemistry 20040301

• Calorie restriction attenuates age-related alterations in the plasma membrane antioxidant system in rat liver.

  Experimental gerontology 20040301

• Inactivation of NADP+-dependent isocitrate dehydrogenase by lipid peroxidation products.

  Free radical research 20040301

• Human mitochondrial glutaredoxin reduces S-glutathionylated proteins with high affinity accepting electrons from either glutathione or thioredoxin reductase.

  The Journal of biological chemistry 20040227

• The effect of cytoplasmic Ca2+ signal on the redox state of mitochondrial pyridine nucleotides.

  Molecular and cellular endocrinology 20040227

• Increased myocardial dysfunction after ischemia-reperfusion in mice lacking glucose-6-phosphate dehydrogenase.

  Circulation 20040224

• Cytochrome P450/NADPH-dependent formation of trans epoxides from trans-arachidonic acids.

  Bioorganic & medicinal chemistry letters 20040223

• Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and beta cells.

  The Journal of biological chemistry 20040220

• The soluble and membrane-bound transhydrogenases UdhA and PntAB have divergent functions in NADPH metabolism of Escherichia coli.

  The Journal of biological chemistry 20040220

• Production and characterization of reduced NAADP (nicotinic acid-adenine dinucleotide phosphate).

  The Biochemical journal 20040215

• Metal-Induced reversible structural interconversion of human mitochondrial NAD(P)+-dependent malic enzyme.

  Proteins 20040215

• Characterization of CJ1293, a new UDP-GlcNAc C6 dehydratase from Campylobacter jejuni.

  FEBS letters 20040213

• Respiration-dependent removal of exogenous H2O2 in brain mitochondria: inhibition by Ca2+.

  The Journal of biological chemistry 20040206

• Genome-wide transcriptional response of a Saccharomyces cerevisiae strain with an altered redox metabolism.

  Biotechnology and bioengineering 20040205

• A positive charge at position 33 of thioredoxin primarily affects its interaction with other proteins but not redox potential.

  Biochemistry 20040203

• Selection of human cytochrome P450 1A2 mutants with enhanced catalytic activity for heterocyclic amine N-hydroxylation.

  Biochemistry 20040203

• Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells.

  Endocrinology 20040201

• Synthesis and utility of 14C-labeled nicotinamide cofactors.

  Analytical biochemistry 20040201

• Structural alteration of cofactor specificity in Corynebacterium 2,5-diketo-D-gluconic acid reductase.

  Protein science : a publication of the Protein Society 20040201

• Anthocyanidin reductases from Medicago truncatula and Arabidopsis thaliana.

  Archives of biochemistry and biophysics 20040201

• Increased NADPH-oxidase activity and Nox4 expression during chronic hypertension is associated with enhanced cerebral vasodilatation to NADPH in vivo.

  Stroke 20040201

• Cyclic AMP-dependent tyrosine phosphorylation in tammar wallaby (Macropus eugenii) spermatozoa.

  Journal of experimental zoology. Part A, Comparative experimental biology 20040201

• Superoxide generation by Nox1 in guinea pig gastric mucosal cells involves a component with p67(phox)-ability.

  Biological & pharmaceutical bulletin 20040201

• Mechanism-based inactivation of cytochrome P450 3A4 by 4-ipomeanol.

  Chemical research in toxicology 20040201

• Isoflavones inhibit 3-hydroxy-3-methylglutaryl coenzyme A reductase in vitro.

  Bioscience, biotechnology, and biochemistry 20040201

• Synthesis and antioxidant properties of some novel benzimidazole derivatives on lipid peroxidation in the rat liver.

  Archives of pharmacal research 20040201

• Potent inhibition of human cytochrome P450 1 enzymes by dimethoxyphenylvinyl thiophene.

  Archives of pharmacal research 20040201

• Disruption of the plr1+ gene encoding pyridoxal reductase of Schizosaccharomyces pombe.

  Journal of biochemistry 20040201

• Endogenous NADPH-dependent aldose reductase activity influences product formation during xylose consumption in recombinant Saccharomyces cerevisiae.

  Yeast (Chichester, England) 20040130

• Interactions of quinones with thioredoxin reductase: a challenge to the antioxidant role of the mammalian selenoprotein.

  The Journal of biological chemistry 20040123

• CO2, not HCO3-, facilitates oxidations by Cu,Zn superoxide dismutase plus H2O2.

  Proceedings of the National Academy of Sciences of the United States of America 20040120

• Effect of cofactor binding and loop conformation on side chain methyl dynamics in dihydrofolate reductase.

  Biochemistry 20040120

• Electron transfer in human methionine synthase reductase studied by stopped-flow spectrophotometry.

  Biochemistry 20040120

• Hydroxylation by the hydroperoxy-iron species in cytochrome P450 enzymes.

  Journal of the American Chemical Society 20040114

• Disruption of aldehyde reductase increases group size in dictyostelium.

  The Journal of biological chemistry 20040109

• Protective effect of ascorbate against oxidative stress in the mouse lens.

  Biochimica et biophysica acta 20040105

• Centrifugal visual system of Crocodylus niloticus: a hodological, histochemical, and immunocytochemical study.

  The Journal of comparative neurology 20040101

• Synthesis of R and S tritiated reduced beta-nicotinamide adenine dinucleotide 2' phosphate.

  Analytical biochemistry 20040101

• Purification, characterization and kinetic properties of the multifunctional thioredoxin-glutathione reductase from Taenia crassiceps metacestode (cysticerci).

  Molecular and biochemical parasitology 20040101

• Cytochrome c oxidase is decreased in Alzheimer's disease platelets.

  Neurobiology of aging 20040101

• Metabolism of apigenin by rat liver phase I and phase ii enzymes and by isolated perfused rat liver.

  Drug metabolism and disposition: the biological fate of chemicals 20040101

• Highly selective inhibition of human CYP3Aa in vitro by azamulin and evidence that inhibition is irreversible.

  Drug metabolism and disposition: the biological fate of chemicals 20040101

• Metabolism and mutagenicity of source water contaminants 1,3-dichloropropane and 2,2-dichloropropane.

  Drug metabolism and disposition: the biological fate of chemicals 20040101

• Oxidative one-carbon cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes.

  Xenobiotica; the fate of foreign compounds in biological systems 20040101

• Effects of excess nicotinamide administration on the urinary excretion of nicotinamide N-oxide and nicotinuric acid by rats.

  Bioscience, biotechnology, and biochemistry 20040101

• Bacillus subtilis ypgA gene is fni, a nonessential gene encoding type 2 isopentenyl diphosphate isomerase.

  Bioscience, biotechnology, and biochemistry 20040101

• A novel mutation in the glucose-6-phosphate dehydrogenase gene in a subject with chronic nonspherocytic hemolytic anemia--characterization of enzyme using yeast expression system and molecular modeling.

  Blood cells, molecules & diseases 20040101

• NADP-glutamate dehydrogenase activity is increased under hyperosmotic conditions in the halotolerant yeast Debaryomyces hansenii.

  Current microbiology 20040101

• Understanding and improving NADPH-dependent reactions by nongrowing Escherichia coli cells.

  Biotechnology progress 20040101

• An examination of d-amphetamine self-administration in pedunculopontine tegmental nucleus-lesioned rats.

  Neuroscience 20040101

• Antimycin A treatment decreases respiratory internal rotenone-insensitive NADH oxidation capacity in potato leaves.

  BMC plant biology 20040101

• Cytosolic NADP phosphatases I and II from Arthrobacter sp. strain KM: implication in regulation of NAD+/NADP+ balance.

  Journal of basic microbiology 20040101

• [Activity of the key enzymes in xylose-assimilating yeasts at different rates of oxygen transfer to the fermentation medium].

  Mikrobiologiia 20040101

• [Analysis of the kinetics of Ca2+ signals in Ehrlich ascites tumor cells upon the inhibition of the mitochondrial Na+/Ca2+ exchanger].

  Biofizika 20040101

• Circadian tracking of nicotinamide cofactor levels in an immortalized suprachiasmatic nucleus cell line.

  Neuroscience 20040101

• Integrated analysis of metabolic phenotypes in Saccharomyces cerevisiae.

  BMC genomics 20040101

• Repression of reserve lipid turnover in Cunninghamella echinulata and Mortierella isabellina cultivated in multiple-limited media.

  Journal of applied microbiology 20040101

• [Cytochrome P450 activity and its alteration in different diseases].

  Revista medica de Chile 20040101

• Administration of Ginseng radix decreases nitric oxide synthase expression in the hippocampus of streptozotocin-induced diabetic rats.

  The American journal of Chinese medicine 20040101

• The ability of new sugar-modified derivatives of antitumor anthracycline, daunorubicin, to stimulate NAD(P)H oxidation in different cellular oxidoreductase systems: NADH dehydrogenase, NADPH cytochrome P450 reductase, and xanthine oxidase.

  Oncology research 20040101

• Modulation of NADP(+)-dependent isocitrate dehydrogenase in aging.

  Redox report : communications in free radical research 20040101

• Various mutations by using yeast gene for protein-engineering.

  Nucleic acids symposium series (2004) 20040101

• Multiple forms of xylose reductase in Candida intermedia: comparison of their functional properties using quantitative structure-activity relationships, steady-state kinetic analysis, and pH studies.

  Journal of agricultural and food chemistry 20031231

• Palmitate-induced Ca2+-signaling in pancreatic beta-cells.

  Molecular and cellular endocrinology 20031230

• Membrane properties induced by anionic phospholipids and phosphatidylethanolamine are critical for the membrane binding and catalytic activity of human cytochrome P450 3A4.

  Biochemistry 20031230

• Structural elements contribute to the calcium/calmodulin dependence on enzyme activation in human endothelial nitric-oxide synthase.

  The Journal of biological chemistry 20031226

• Evidence for a subgroup of thioredoxin h that requires GSH/Grx for its reduction.

  FEBS letters 20031218

• Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases and their relationship to isoflavone reductases.

  The Journal of biological chemistry 20031212

• Glutaredoxin exerts an antiapoptotic effect by regulating the redox state of Akt.

  The Journal of biological chemistry 20031212

• 1,2-benzisoxazole phosphorodiamidates as novel anticancer prodrugs requiring bioreductive activation.

  Journal of medicinal chemistry 20031204

• Pentose phosphate pathway coordinates multiple redox-controlled relaxing mechanisms in bovine coronary arteries.

  American journal of physiology. Heart and circulatory physiology 20031201

• Signal processing times in neutrophil activation: dependence on ligand concentration and the relative phase of metabolic oscillations.

  Biophysical chemistry 20031201

• Significance of phosphoglucose isomerase for the shift between heterolactic and mannitol fermentation of fructose by Oenococcus oeni.

  Archives of microbiology 20031201

• Purification and properties of the formate dehydrogenase and characterization of the fdhA gene of Sulfurospirillum multivorans.

  Archives of microbiology 20031201

• Rational proteomics I. Fingerprint identification and cofactor specificity in the short-chain oxidoreductase (SCOR) enzyme family.

  Proteins 20031201

• Aldose reductase and the importance of experimental design.

  Biochemical Society transactions 20031201

• Crystallization and preliminary X-ray crystallographic studies of NADP-dependent 3-hydroxyisobutyrate dehydrogenase from Thermus thermophilus HB8.

  Acta crystallographica. Section D, Biological crystallography 20031201

• Superoxide does not mediate the acute vasoconstrictor effects of angiotensin II: a study in human and porcine arteries.

  Journal of hypertension 20031201

• Novel Ca2+ signalling mechanisms in vascular myocytes: symposium overview.

  Acta physiologica Scandinavica 20031201

• Isolated durum wheat and potato cell mitochondria oxidize externally added NADH mostly via the malate/oxaloacetate shuttle with a rate that depends on the carrier-mediated transport.

  Plant physiology 20031201

• Polyhydroxyalkanoate (PHA) biosynthesis in Thermus thermophilus: purification and biochemical properties of PHA synthase.

  Molecular and cellular biochemistry 20031201

• Induction of NAD(P)H:quinone reductase by probucol: a possible mechanism for protection against chemical carcinogenesis and toxicity.

  Pharmacology & toxicology 20031201

• Reduction of nilutamide by NO synthases: implications for the adverse effects of this nitroaromatic antiandrogen drug.

  Chemical research in toxicology 20031201

• Transaldolase/glucose-6-phosphate isomerase bifunctional enzyme and ribulokinase as factors to increase xylitol production from D-arabitol in Gluconobacter oxydans.

  Bioscience, biotechnology, and biochemistry 20031201

• Coenzyme specificity of enzymes in the oxidative pentose phosphate pathway of Gluconobacter oxydans.

  Bioscience, biotechnology, and biochemistry 20031201

• Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543.

  Xenobiotica; the fate of foreign compounds in biological systems 20031201

• S-oxidation of S-methyl-esonarimod by flavin-containing monooxygenases in human liver microsomes.

  Xenobiotica; the fate of foreign compounds in biological systems 20031201

• Pharmacokinetics and metabolism of NO-1886, a lipoprotein lipase-promoting agent, in cynomolgus monkey.

  Xenobiotica; the fate of foreign compounds in biological systems 20031201

• Tryptophan phosphorescence spectroscopy reveals that a domain in the NAD(H)-binding component (dI) of transhydrogenase from Rhodospirillum rubrum has an extremely rigid and conformationally homogeneous protein core.

  The Journal of biological chemistry 20031128

• Iron-sulfur cluster N2 of the Escherichia coli NADH:ubiquinone oxidoreductase (complex I) is located on subunit NuoB.

  The Journal of biological chemistry 20031128

• Reaction-path energetics and kinetics of the hydride transfer reaction catalyzed by dihydrofolate reductase.

  Biochemistry 20031125

• Histidine ligand protonation and redox potential in the rieske dioxygenases: role of a conserved aspartate in anthranilate 1,2-dioxygenase.

  Biochemistry 20031125

• A novel metabolic cycle catalyzes glucose oxidation and anaplerosis in hungry Escherichia coli.

  The Journal of biological chemistry 20031121

• Extracellular alkalosis activates ERK mitogen-activated protein kinase of vascular smooth muscle cells through NADPH-mediated formation of reactive oxygen species.

  FEBS letters 20031120

• Mechanism-based inactivation of thioredoxin reductase from Plasmodium falciparum by Mannich bases. Implication for cytotoxicity.

  Biochemistry 20031118

• Nicotinamide adenine dinucleotide (phosphate) reduced:quinone oxidoreductase and glutathione S-transferase M1 polymorphisms and childhood asthma.

  American journal of respiratory and critical care medicine 20031115

• Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase.

  Archives of biochemistry and biophysics 20031115

• Microscale synthesis of 2-tritiated isopropanol and 4R-tritiated reduced nicotinamide adenine dinucleotide phosphate.

  Analytical biochemistry 20031115

• Thyroid hormones in the rat amygdala as common targets for antidepressant drugs, mood stabilizers, and sleep deprivation.

  Biological psychiatry 20031115

• Essential glycine in the proton channel of Escherichia coli transhydrogenase.

  The Journal of biological chemistry 20031114

• Superoxide generation mediated by 8-nitroguanosine, a highly redox-active nucleic acid derivative.

  Biochemical and biophysical research communications 20031114

• Evidence for environmentally coupled hydrogen tunneling during dihydrofolate reductase catalysis.

  Journal of the American Chemical Society 20031105

• Regio- and enantioselective alkane hydroxylation with engineered cytochromes P450 BM-3.

  Journal of the American Chemical Society 20031105

• The Pseudomonas secretory product pyocyanin inhibits catalase activity in human lung epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20031101

• Molecular and structural characterization of NADPH-dependent d-glycerate dehydrogenase from the enteric parasitic protist Entamoeba histolytica.

  The Biochemical journal 20031101

• IDH1 gene transcription is sterol regulated and activated by SREBP-1a and SREBP-2 in human hepatoma HepG2 cells: evidence that IDH1 may regulate lipogenesis in hepatic cells.

  Journal of lipid research 20031101

• Multiple forms of redox activity in populations of human spermatozoa.

  Molecular human reproduction 20031101

• Plastoquinones are effectively reduced by ferredoxin:NADP+ oxidoreductase in the presence of sodium cholate micelles. Significance for cyclic electron transport and chlororespiration.

  Phytochemistry 20031101

• Sequential injection analysis of nitrites and nitrates in human serum using nitrate reductase.

  Clinica chimica acta; international journal of clinical chemistry 20031101

• Reduced nicotinamide adenine dinucleotide phosphate and the higher incidence of pollution-induced liver cancer in female flounder.

  Environmental toxicology and chemistry 20031101

• Metabolism of estrogens and androgens by scleractinian corals.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20031101

• Purification and characterization of glutathione reductase from bovine erythrocytes.

  Preparative biochemistry & biotechnology 20031101

• Methemoglobinemia and eccentrocytosis in equine erythrocyte flavin adenine dinucleotide deficiency.

  Veterinary pathology 20031101

• NO-generating neurons in the medullary cardiovascular centers of rodents and carnivores.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20031101

• Cortisol metabolism and visceral obesity: role of 11beta-hydroxysteroid dehydrogenase type I enzyme and reduced co-factor NADPH.

  Endocrine research 20031101

• Purification, analysis, and preservation of reduced nicotinamide adenine dinucleotide 2'-phosphate.

  Analytical biochemistry 20031101

• Single-sample preparation for simultaneous cellular redox and energy state determination.

  Analytical biochemistry 20031101

• A continuous assay of myristoyl-CoA:protein N-myristoyltransferase for proteomic analysis.

  Analytical biochemistry 20031101

• [Purification and characterization of glutamate dehydrogenase. from Corynebacterium glutamicum S9114].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20031101

• Crystal structure of Escherichia coli PdxA, an enzyme involved in the pyridoxal phosphate biosynthesis pathway.

  The Journal of biological chemistry 20031031

• Conformational change in the NADP(H) binding domain of transhydrogenase defines four states.

  Biochemistry 20031028

• Critical role of histidine residues in cyclohexanone monooxygenase expression, cofactor binding and catalysis.

  Chemico-biological interactions 20031025

• Effects of hydrogen peroxide upon nicotinamide nucleotide metabolism in Escherichia coli: changes in enzyme levels and nicotinamide nucleotide pools and studies of the oxidation of NAD(P)H by Fe(III).

  The Journal of biological chemistry 20031024

• The oxidant-responsive diaphorase of Rhodobacter capsulatus is a ferredoxin (flavodoxin)-NADP(H) reductase.

  FEBS letters 20031023

• Complete reversal of coenzyme specificity by concerted mutation of three consecutive residues in alcohol dehydrogenase.

  The Journal of biological chemistry 20031017

• Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD34+ cells.

  Blood 20031015

• Reactive oxygen species promote tyrosine phosphorylation and capacitation in equine spermatozoa.

  Theriogenology 20031015

• Relaxing the nicotinamide cofactor specificity of phosphite dehydrogenase by rational design.

  Biochemistry 20031014

• Control of energy dissipation and photochemical activity in photosystem I by NADP-dependent reversible conformational changes.

  Biochemistry 20031014

• Kinetics of the superoxide reductase catalytic cycle.

  The Journal of biological chemistry 20031010

• Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family, from cultured Coptis japonica cells.

  The Journal of biological chemistry 20031003

• Redundancy in the pathway for redox regulation of mammalian methionine synthase: reductive activation by the dual flavoprotein, novel reductase 1.

  The Journal of biological chemistry 20031003

• Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1.

  The Journal of biological chemistry 20031003

• Glucose conversion by multiple pathways in brain extract: theoretical and experimental analysis.

  Biochemical and biophysical research communications 20031003

• NAADP activates a Ca2+ current that is dependent on F-actin cytoskeleton.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031001

• Biochemical and functional properties of a pyruvate formate-lyase (PFL)-activating system in Streptococcus mutans.

  Oral microbiology and immunology 20031001

• Diagnostic chemical shift markers for loop conformation and substrate and cofactor binding in dihydrofolate reductase complexes.

  Protein science : a publication of the Protein Society 20031001

• Different antioxidant effects of polyphenols on lipid peroxidation and hydroxyl radicals in the NADPH-, Fe-ascorbate- and Fe-microsomal systems.

  Biochemical pharmacology 20031001

• Structure and mechanism of a bacterial haloalcohol dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site.

  The EMBO journal 20031001

• Aerobic physiology of redox-engineered Saccharomyces cerevisiae strains modified in the ammonium assimilation for increased NADPH availability.

  FEMS yeast research 20031001

• Mechanism-based inhibition of CYP activities in rat liver by fluoxetine and structurally similar alkylamines.

  Xenobiotica; the fate of foreign compounds in biological systems 20031001

• Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol.

  Cancer research 20031001

• Inhibition of the group I ribozyme splicing by NADP+.

  Molecular and cellular biochemistry 20031001

• Presence of functional domains in NADPH-dependent cytosolic 3,5,3'-Triiodo-L-thyronine (T3)-binding protein (p38CTBP) molecule: analyses with deletion mutants.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20031001

• Sensitization of U937 cells to heat shock by oxalomalate, a competitive inhibitor of NADP+-dependent isocitrate dehydrogenase.

  Free radical research 20031001

• [Pathomechanism of hyperlipoproteinemia in chronic renal failure].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20031001

• Cytochrome P450-mediated oxidative damage of nuclear membrane proteins and its prevention by vitamin C.

  Indian journal of biochemistry & biophysics 20031001

• NMR studies of the interaction of a type II dihydrofolate reductase with pyridine nucleotides reveal unexpected phosphatase and reductase activity.

  Biochemistry 20030930

• Engineering and characterization of a NADPH-utilizing cytochrome b5 reductase.

  Biochemistry 20030930

• Conformational changes combined with charge-transfer interactions are essential for reduction in catalysis by p-hydroxybenzoate hydroxylase.

  Biochemistry 20030930

• Substrate specificity and kinetic isotope effect analysis of the Eschericia coli ketopantoate reductase.

  Biochemistry 20030930

• Cofactor determination and spectroscopic characterization of the selenium-dependent purine hydroxylase from Clostridium purinolyticum.

  Biochemistry 20030930

• The crystal structure and reaction mechanism of Escherichia coli 2,4-dienoyl-CoA reductase.

  The Journal of biological chemistry 20030926

• Functional split and crosslinking of the membrane domain of the beta subunit of proton-translocating transhydrogenase from Escherichia coli.

  Biochemistry 20030923

• Crystal structure of the monomeric isocitrate dehydrogenase in the presence of NADP+: insight into the cofactor recognition, catalysis, and evolution.

  The Journal of biological chemistry 20030919

• Role of ionic interactions in ligand binding and catalysis of R67 dihydrofolate reductase.

  Biochemistry 20030916

• The three-dimensional structures of the Mycobacterium tuberculosis dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes. Structural and mutagenic analysis of relaxed nucleotide specificity.

  Biochemistry 20030916

• Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase.

  Biochemistry 20030916

• Nicotinamide adenine dinucleotide phosphate-regenerating system coupled to a glutathione-reductase microtiter method for determination of total glutathione concentrations in adherent growing cancer cell lines.

  Analytical biochemistry 20030915

• Depletion of Kupffer cell function by gadolinium chloride attenuates thioacetamide-induced hepatotoxicity. Expression of metallothionein and HSP70.

  Biochemical pharmacology 20030915

• Occurrence of two different glutamate dehydrogenase activities in the halophilic bacterium Salinibacter ruber.

  FEMS microbiology letters 20030912

• Systemic metabolic reactions are obtained by singular value decomposition of genome-scale stoichiometric matrices.

  Journal of theoretical biology 20030907

• Metabolic phenotype of phosphoglucose isomerase mutants of Corynebacterium glutamicum.

  Journal of biotechnology 20030904

• Pre-steady-state and steady-state kinetic analysis of E. coli class I ribonucleotide reductase.

  Biochemistry 20030902

• Hydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima.

  The Biochemical journal 20030901

• Phenazine-1-carboxylic acid, a secondary metabolite of Pseudomonas aeruginosa, alters expression of immunomodulatory proteins by human airway epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20030901

• Characterization of the Tuber borchii nitrate reductase gene and its role in ectomycorrhizae.

  Molecular genetics and genomics : MGG 20030901

• Regulation of brain mitochondrial H2O2 production by membrane potential and NAD(P)H redox state.

  Journal of neurochemistry 20030901

• Structure of pteridine reductase (PTR1) from Leishmania tarentolae.

  Acta crystallographica. Section D, Biological crystallography 20030901

• Intermittent hypobaric hypoxia increases the ability of neutrophils to generate superoxide anion in humans.

  Clinical and experimental pharmacology & physiology 20030901

• Jasmonate-induced epoxidation of tabersonine by a cytochrome P-450 in hairy root cultures of Catharanthus roseus.

  Phytochemistry 20030901

• Generation of oxidant stress in cultured endothelial cells by methylene blue: protective effects of glucose and ascorbic acid.

  Biochemical pharmacology 20030901

• Inhibitory effects and spectral interactions of isomeric methoxyindazoles on recombinant nitric oxide synthases.

  Nitric oxide : biology and chemistry 20030901

• Interactions between transhydrogenase and thio-nicotinamide Analogues of NAD(H) and NADP(H) underline the importance of nucleotide conformational changes in coupling to proton translocation.

  The Journal of biological chemistry 20030829

• Redox potential of human thioredoxin 1 and identification of a second dithiol/disulfide motif.

  The Journal of biological chemistry 20030829

• The mechanism of high Mr thioredoxin reductase from Drosophila melanogaster.

  The Journal of biological chemistry 20030829

• The involvement of glucose metabolism in the regulation of inducible nitric oxide synthase gene expression in glial cells: possible role of glucose-6-phosphate dehydrogenase and CCAAT/enhancing binding protein.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030820

• Thermodynamics and kinetics of the hydride-transfer cycles for 1-aryl-1,4-dihydronicotinamide and its 1,2-dihydroisomer.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030818

• Mechanistic studies on the intramolecular one-electron transfer between the two flavins in the human neuronal nitric-oxide synthase and inducible nitric-oxide synthase flavin domains.

  The Journal of biological chemistry 20030815

• Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids.

  Journal of molecular biology 20030815

• A flux model of glycolysis and the oxidative pentosephosphate pathway in developing Brassica napus embryos.

  The Journal of biological chemistry 20030808

• Quaternary structure of Azospirillum brasilense NADPH-dependent glutamate synthase in solution as revealed by synchrotron radiation x-ray scattering.

  The Journal of biological chemistry 20030808

• High throughput screening identifies novel inhibitors of Escherichia coli dihydrofolate reductase that are competitive with dihydrofolate.

  Bioorganic & medicinal chemistry letters 20030804

• Cofactor recycling mechanism in asymmetric biocatalytic reduction of carbonyl compounds mediated by yeast: which is the efficient electron donor?

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030804

• Regulation of 11 beta-hydroxysteroid dehydrogenase enzymes in the rat kidney by estradiol.

  American journal of physiology. Endocrinology and metabolism 20030801

• Metabotropic receptor-mediated Ca2+ signaling elevates mitochondrial Ca2+ and stimulates oxidative metabolism in hippocampal slice cultures.

  Journal of neurophysiology 20030801

• Probing electrostatic channeling in protozoal bifunctional thymidylate synthase-dihydrofolate reductase using site-directed mutagenesis.

  The Journal of biological chemistry 20030801

• Predictive value of comparative molecular field analysis modelling of naphthalene inhibition of human CYP2A6 and mouse CYP2A5 enzymes.

  Toxicology in vitro : an international journal published in association with BIBRA 20030801

• Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency.

  Nature genetics 20030801

• Oxalomalate, a competitive inhibitor of NADP+-dependent isocitrate dehydrogenase, enhances lipid peroxidation-mediated oxidative damage in U937 cells.

  Archives of biochemistry and biophysics 20030801

• Cytotoxicity of RH1 and related aziridinylbenzoquinones: involvement of activation by NAD(P)H:quinone oxidoreductase (NQO1) and oxidative stress.

  Archives of biochemistry and biophysics 20030801

• Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.

  Endocrinology 20030801

• Substituent effect on the reductive N-dearylation of 3-(indol-1-yl)-1,2-benzisoxazoles by rat liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20030801

• Roles of human CYP2A6 and 2B6 and rat CYP2C11 and 2B1 in the 10-hydroxylation of (-)-verbenone by liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20030801

• Ovarian modulators of type 1 11beta-hydroxysteroid dehydrogenase (11betaHSD) activity and intra-follicular cortisol:cortisone ratios correlate with the clinical outcome of IVF.

  Human reproduction (Oxford, England) 20030801

• NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death.

  The EMBO journal 20030801

• Intracellular redox status modulates monocyte chemoattractant protein-1 expression stimulated by homocysteine in endothelial cells.

  Journal of cardiovascular pharmacology 20030801

• [Separation of hydrophobic NAD(P)H dehydrogenase subcomplexes from cyanobacterium Synechocystis PCC6803].

  Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20030801

• Shikimate dehydrogenase structure reveals novel fold.

  Structure (London, England : 1993) 20030801

• Crystal structure of shikimate 5-dehydrogenase (SDH) bound to NADP: insights into function and evolution.

  Structure (London, England : 1993) 20030801

• Interaction of polyhalogenated compounds of appropriate configuration with mammalian or bacterial CYP enzymes. Increased bilirubin and uroporphyrinogen oxidation in vitro.

  Biochemical pharmacology 20030801

• Recent developments in pyridine nucleotide regeneration.

  Current opinion in biotechnology 20030801

• Endothelium and smooth muscle of pig coronary artery: differences in metabolism.

  Molecular and cellular biochemistry 20030801

• What the lions say.

  Journal of molecular medicine (Berlin, Germany) 20030801

• Fate of the (2Fe-2S)(2+) cluster of Escherichia coli biotin synthase during reaction: a Mössbauer characterization.

  Biochemistry 20030729

• Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases.

  The Biochemical journal 20030715

• Modulation of spontaneous transmitter release from the frog neuromuscular junction by interacting intracellular Ca(2+) stores: critical role for nicotinic acid-adenine dinucleotide phosphate (NAADP).

  The Biochemical journal 20030715

• Pyridine nucleotide regulation of the KATP channel Kir6.2/SUR1 expressed in Xenopus oocytes.

  The Journal of physiology 20030715

• Murine hexose-6-phosphate dehydrogenase: a bifunctional enzyme with broad substrate specificity and 6-phosphogluconolactonase activity.

  Archives of biochemistry and biophysics 20030715

• A novel flavin-containing monooxygenase from Methylophaga sp strain SK1 and its indigo synthesis in Escherichia coli.

  Biochemical and biophysical research communications 20030711

• Ischemic preconditioning inhibits mitochondrial respiration, increases H2O2 release, and enhances K+ transport.

  American journal of physiology. Heart and circulatory physiology 20030701

• AOPP-induced activation of human neutrophil and monocyte oxidative metabolism: a potential target for N-acetylcysteine treatment in dialysis patients.

  Kidney international 20030701

• Metabolism-based inactivation of neuronal nitric-oxide synthase by components of cigarette and cigarette smoke.

  Drug metabolism and disposition: the biological fate of chemicals 20030701

• Glycerol dehydrogenase, encoded by gldB is essential for osmotolerance in Aspergillus nidulans.

  Molecular microbiology 20030701

• Role of nitric oxide in anorectal function of normal and neuronal nitric oxide synthase knockout mice: a novel approach to anorectal disease.

  Diseases of the colon and rectum 20030701

• Hexose monophosphate shunt activities in human erythrocytes during oxidative damage induced by hydrogen peroxide.

  Archives of toxicology 20030701

• In vivo changes of the oxidation-reduction state of NADP and of the ATP/ADP cellular ratio linked to the photosynthetic activity in Chlamydomonas reinhardtii.

  Plant physiology 20030701

• Identification and differential expression of two thioredoxin h isoforms in germinating seeds from pea.

  Plant physiology 20030701

• In vitro formation of quinoid metabolites of the dietary supplement Cimicifuga racemosa (black cohosh).

  Chemical research in toxicology 20030701

• Volatilization of mercury by an iron oxidation enzyme system in a highly mercury-resistant Acidithiobacillus ferrooxidans strain MON-1.

  Bioscience, biotechnology, and biochemistry 20030701

• Characterization and regulation of NADP+-isocitrate dehydrogenase from Saccharopolyspora erythraea.

  Biotechnology letters 20030701

• Redox reactions and electron transfer across the red cell membrane.

  IUBMB life 20030701

• Impaired cortical energy metabolism but not major antioxidant defenses in experimental bacterial meningitis.

  Brain research 20030627

• Characterization of Drosophila nitric oxide synthase: a biochemical study.

  Biochemical and biophysical research communications 20030627

• Crystal structure of the vertebrate NADP(H)-dependent alcohol dehydrogenase (ADH8).

  Journal of molecular biology 20030627

• Increased myocardial NADPH oxidase activity in human heart failure.

  Journal of the American College of Cardiology 20030618

• Proton translocation by transhydrogenase.

  FEBS letters 20030612

• Enhanced MTT-reducing activity under growth inhibition by resveratrol in CEM-C7H2 lymphocytic leukemia cells.

  Cancer letters 20030610

• Properties of the apo-form of the NADP(H)-binding domain III of proton-pumping Escherichia coli transhydrogenase: implications for the reaction mechanism of the intact enzyme.

  Biochimica et biophysica acta 20030605

• EPR study of light-induced regulation of photosynthetic electron transport in Synechocystis sp. strain PCC 6803.

  FEBS letters 20030605

• Roles of individual amino acids in helix 14 of the membrane domain of proton-translocating transhydrogenase from Escherichia coli as deduced from cysteine mutagenesis.

  Biochemistry 20030603

• Ovarian modulators of 11beta-hydroxysteroid dehydrogenase (11beta HSD) activity in follicular fluid from bovine and porcine large antral follicles and spontaneous ovarian cysts.

  Biology of reproduction 20030601

• Kinetic, spectroscopic and thermodynamic characterization of the Mycobacterium tuberculosis adrenodoxin reductase homologue FprA.

  The Biochemical journal 20030601

• Do multiple cytochrome P450 isoforms contribute to parathion metabolism in man?

  Archives of toxicology 20030601

• Universal distribution of c-kit-positive cells in different types of Hirschsprung's disease.

  Pediatric surgery international 20030601

• Identification of 3,5-diiodo-L-thyronine-binding proteins in rat liver cytosol by photoaffinity labeling.

  Endocrinology 20030601

• Outlines for the definition of halotolerance/halophily in yeasts: Candida versatilis (halophila) CBS4019 as the archetype?

  FEMS yeast research 20030601

• Thyroid Ca2+/NADPH-dependent H2O2 generation is partially inhibited by propylthiouracil and methimazole.

  European journal of biochemistry 20030601

• Quinol-based metabolic cycle for estrogens in rat liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20030601

• Purification of glucose 6-phosphate dehydrogenase from Buffalo (Bubalus bubalis) erythrocytes and investigation of some kinetic properties.

  Protein expression and purification 20030601

• Expression of nitric oxide synthase immunoreactivity in the human female intramural striated urethral sphincter.

  The Journal of urology 20030601

• Efficacy of edaravone, a free radical scavenger, on left ventricular function and structure in diabetes mellitus.

  Journal of cardiovascular pharmacology 20030601

• An improved, simple screening method for detection of glucose-6-phosphate dehydrogenase deficiency.

  Tropical medicine & international health : TM & IH 20030601

• Difference in uptake and toxicity of trivalent and pentavalent inorganic arsenic in rat heart microvessel endothelial cells.

  Archives of toxicology 20030601

• Co-ordination of Ca(2+) signalling in mammalian cells by the new Ca(2+)-releasing messenger NAADP.

  Pflugers Archiv : European journal of physiology 20030601

• Aldehydic DNA lesions induced by catechol estrogens in calf thymus DNA.

  Carcinogenesis 20030601

• Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice.

  Clinical pharmacology and therapeutics 20030601

• Reactive oxygen species induce swelling and cytochrome c release but not transmembrane depolarization in isolated rat brain mitochondria.

  British journal of pharmacology 20030601

• Induction of NAD(P)H quinone: oxidoreductase1 inhibits carcinogen-induced aberrant crypt foci in colons of Sprague-Dawley rats.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20030601

• High-throughput screen for inhibitors of 1-deoxy-d-xylulose 5-phosphate reductoisomerase by surrogate ligand competition.

  Journal of biomolecular screening 20030601

• Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants.

  Protein engineering 20030601

• The natural antioxidant otobaphenol delays the permeability transition of mitochondria and induces their aggregation.

  Antioxidants & redox signaling 20030601

• 8-Methoxy-naphtho[2,3-b]thiophen-4,9-quinone, a non-competitive inhibitor of trypanothione reductase.

  Memorias do Instituto Oswaldo Cruz 20030601

• Biliverdin reductase from the liver of Atlantic salmon (Salmo salar).

  Biochemistry. Biokhimiia 20030601

• Iron and CYP2E1-dependent oxidative stress and toxicity.

  Alcohol (Fayetteville, N.Y.) 20030601

• Reversal of the apparent regiospecificity of NAD(P)H-dependent hydride transfer: the properties of the difluoromethylene group, a carbonyl mimic.

  Journal of the American Chemical Society 20030528

• Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities.

  The Journal of biological chemistry 20030523

• The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria.

  The Journal of biological chemistry 20030523

• Capturing enzyme structure prior to reaction initiation: tropinone reductase-II-substrate complexes.

  Biochemistry 20030520

• Ascorbate-mediated LHCII protein phosphorylation--LHCII kinase regulation in light and in darkness.

  Biochemistry 20030520

• Dual effect of ebselen on mitochondrial permeability transition.

  Biochemical pharmacology 20030515

• The CXC motif: a functional mimic of protein disulfide isomerase.

  Biochemistry 20030513

• S-15176 inhibits mitochondrial permeability transition via a mechanism independent of its antioxidant properties.

  European journal of pharmacology 20030509

• Pharmacophore-based molecular docking to account for ligand flexibility.

  Proteins 20030501

• Automated generation of MCSS-derived pharmacophoric DOCK site points for searching multiconformation databases.

  Proteins 20030501

• Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical.

  Journal of pineal research 20030501

• A novel electro-optical sensor format with generic applicability for exploitation with NAD(P) dependent enzymes.

  Biosensors & bioelectronics 20030501

• Open questions in ferredoxin-NADP+ reductase catalytic mechanism.

  European journal of biochemistry 20030501

• NAADP on the up in pancreatic beta cells-a sweet message?

  BioEssays : news and reviews in molecular, cellular and developmental biology 20030501

• Cinnamic acid 4-hydroxylase from cell cultures of the hornwort Anthoceros agrestis.

  Planta 20030501

• A novel NADH kinase is the mitochondrial source of NADPH in Saccharomyces cerevisiae.

  The EMBO journal 20030501

• Placental 11beta-hydroxysteroid dehydrogenase in Dahl and spontaneously hypertensive rats.

  American journal of hypertension 20030501

• Site-directed mutational analysis of the novel catalytic domains of alpha-aminoadipate reductase (Lys2p) from Candida albicans.

  Molecular genetics and genomics : MGG 20030501

• A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.

  Metabolism: clinical and experimental 20030501

• Superoxide synthase and dismutase activity of plasma membranes from maize roots.

  Protoplasma 20030501

• Regeneration of lipophilic antioxidants by NAD(P)H:quinone oxidoreductase 1.

  Protoplasma 20030501

• Denitrification of nitrate by the fungus Cylindrocarpon tonkinense.

  Bioscience, biotechnology, and biochemistry 20030501

• Purification of recombinant non-phosphorylating NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Streptococcus pyogenes expressed in E. coli.

  Molecular and cellular biochemistry 20030501

• Role of glucose in the bioconversion of fructose into mannitol by Candida magnoliae.

  Biotechnology letters 20030501

• A history of research on yeasts 5: the fermentation pathway.

  Yeast (Chichester, England) 20030430

• Dual coenzyme specificity of photosynthetic glyceraldehyde-3-phosphate dehydrogenase interpreted by the crystal structure of A4 isoform complexed with NAD.

  Biochemistry 20030429

• Crystal structure of class I acetohydroxy acid isomeroreductase from Pseudomonas aeruginosa.

  Journal of molecular biology 20030425

• The ALD6 gene product is indispensable for providing NADPH in yeast cells lacking glucose-6-phosphate dehydrogenase activity.

  The Journal of biological chemistry 20030418

• Testing the relationship between foldability and the early folding events of dihydrofolate reductase from Escherichia coli.

  Journal of molecular biology 20030418

• Polysiloxane-supported NAD(P)H model 1-benzyl-1,4-dihydronicotinamide: synthesis and application in the reduction of activated olefins.

  The Journal of organic chemistry 20030418

• 'Mitochondrial' photochemical drugs do not release toxic amounts of 1O(2) within the mitochondrial matrix space.

  Archives of biochemistry and biophysics 20030415

• Glucocorticoids inhibit interconversion of 7-hydroxy and 7-oxo metabolites of dehydroepiandrosterone: a role for 11beta-hydroxysteroid dehydrogenases?

  Archives of biochemistry and biophysics 20030415

• NAD(P)H fluorescence imaging of postsynaptic neuronal activation in murine hippocampal slices.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415

• Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam.) leaves.

  Journal of agricultural and food chemistry 20030409

• Biochemical and genetic characterization of a novel enzyme of pentitol metabolism: D-arabitol-phosphate dehydrogenase.

  The Biochemical journal 20030401

• Quiescent center formation in maize roots is associated with an auxin-regulated oxidizing environment.

  Development (Cambridge, England) 20030401

• Acetoacetate augments beta-adrenergic inotropism of stunned myocardium by an antioxidant mechanism.

  American journal of physiology. Heart and circulatory physiology 20030401

• Nitric oxide mediated photo-induced cell death in human malignant cells.

  International journal of oncology 20030401

• Effect of iodide on nicotinamide adenine dinucleotide phosphate oxidase activity and Duox2 protein expression in isolated porcine thyroid follicles.

  Endocrinology 20030401

• Participation of superoxide anion in the capacitation of cryopreserved bovine sperm.

  International journal of andrology 20030401

• Radiation response of cells during altered protein thiol redox.

  Radiation research 20030401

• Electron transfer is activated by calmodulin in the flavin domain of human neuronal nitric oxide synthase.

  Archives of biochemistry and biophysics 20030401

• Pulmonary arterial endothelial cells affect the redox status of coenzyme Q0.

  Free radical biology & medicine 20030401

• Use of the mannitol pathway in fructose fermentation of Oenococcus oeni due to limiting redox regeneration capacity of the ethanol pathway.

  Archives of microbiology 20030401

• Determination of the human cytochrome P450s involved in the metabolism of 2n-propylquinoline.

  Xenobiotica; the fate of foreign compounds in biological systems 20030401

• Xylose reductase from the Basidiomycete fungus Cryptococcus flavus: purification, steady-state kinetic characterization, and detailed analysis of the substrate binding pocket using structure-activity relationships.

  Journal of biochemistry 20030401

• Ryanodine receptor type I and nicotinic acid adenine dinucleotide phosphate receptors mediate Ca2+ release from insulin-containing vesicles in living pancreatic beta-cells (MIN6).

  The Journal of biological chemistry 20030328

• EPYLRFamide-mediated reduction of acetylcholine-induced inward currents in Helix lucorum-identified neurones: role of NAADP-dependent and IP3-dependent Ca2+ release from internal stores, calmodulin and Ca2+/calmodulin-dependent protein kinase II.

  Regulatory peptides 20030328

• Functional characterization of beta-ketoacyl-ACP reductase (FabG) from Plasmodium falciparum.

  Biochemical and biophysical research communications 20030328

• Glutamate-115 renders specificity of human 11beta-hydroxysteroid dehydrogenase type 2 for the cofactor NAD+.

  Molecular and cellular endocrinology 20030328

• The crystal structure of R-specific alcohol dehydrogenase from Lactobacillus brevis suggests the structural basis of its metal dependency.

  Journal of molecular biology 20030321

• Failure to increase glucose consumption through the pentose-phosphate pathway results in the death of glucose-6-phosphate dehydrogenase gene-deleted mouse embryonic stem cells subjected to oxidative stress.

  The Biochemical journal 20030315

• Calmodulin-dependent and -independent activation of endothelial nitric-oxide synthase by heat shock protein 90.

  The Journal of biological chemistry 20030314

• Structure-function analysis of enoyl thioester reductase involved in mitochondrial maintenance.

  Journal of molecular biology 20030314

• A study on CYP1A inhibitory action of E-2-(4'-methoxybenzylidene)-1-benzosuberone and some related chalcones and cyclic chalcone analogues.

  Toxicology 20030303

• Inhibitors of 17 beta-hydroxysteroid dehydrogenases.

  Current medicinal chemistry 20030301

• A path from primary protein sequence to ligand recognition.

  Proteins 20030301

• Differential effects of mutations in human endothelial nitric oxide synthase at residues Tyr-357 and Arg-365 on L-arginine hydroxylation and GN-hydroxy-L-arginine oxidation.

  Archives of biochemistry and biophysics 20030301

• Chromaffin cell death induced by 6-hydroxydopamine is independent of mitochondrial swelling and caspase activation.

  Journal of neurochemistry 20030301

• Glucose-6-phosphate dehydrogenase overexpression decreases endothelial cell oxidant stress and increases bioavailable nitric oxide.

  Arteriosclerosis, thrombosis, and vascular biology 20030301

• Reduction of S-nitrosoglutathione by human alcohol dehydrogenase 3 is an irreversible reaction as analysed by electrospray mass spectrometry.

  European journal of biochemistry 20030301

• Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of ethosuximide by human hepatic microsomal enzymes.

  Xenobiotica; the fate of foreign compounds in biological systems 20030301

• Cellular defense against singlet oxygen-induced oxidative damage by cytosolic NADP+-dependent isocitrate dehydrogenase.

  Free radical research 20030301

• Structure of the Clade 1 catalase, CatF of Pseudomonas syringae, at 1.8 A resolution.

  Proteins 20030215

• Characterization and function of mitochondrial nitric-oxide synthase.

  Free radical biology & medicine 20030215

• Thermodynamics of the reduction of NADP with 2-propanol catalyzed by an NADP-dependent alcohol dehydrogenase.

  Archives of biochemistry and biophysics 20030215

• Mechanism of melatonin-induced oscillations in the peroxidase-oxidase reaction.

  Archives of biochemistry and biophysics 20030215

• The coordination of the isomerization of a conserved non-prolyl cis peptide bond with the rate-limiting steps in the folding of dihydrofolate reductase.

  Journal of molecular biology 20030214

• Acupuncture decreases nitric oxide synthase expression in periaqueductal gray area of rats with streptozotocin-induced diabetes.

  Neuroscience letters 20030213

• Glutamine 132 in the NAD(H)-binding component of proton-translocating transhydrogenase tethers the nucleotides before hydride transfer.

  Biochemistry 20030211

• Kinetic locking-on and auxiliary tactics for bioaffinity purification of NADP+-dependent dehydrogenases using N6-linked immobilized NADP+ derivatives: Studies with mammalian and microbial glutamate dehydrogenases.

  Biotechnology and bioengineering 20030205

• NAADP: a new second messenger for glucose-induced Ca2+ responses in clonal pancreatic beta cells.

  Current biology : CB 20030204

• High-resolution structure and biochemical properties of a recombinant Proteus mirabilis catalase depleted in iron.

  Proteins 20030201

• Engineering increased vitamin C levels in plants by overexpression of a D-galacturonic acid reductase.

  Nature biotechnology 20030201

• Exploring the interaction energies for the binding of hydroxydiphenyl ethers to enoyl-acyl carrier protein reductases.

  Journal of biomolecular structure & dynamics 20030201

• Cofactor-independent oxygenation reactions catalyzed by soluble methane monooxygenase at the surface of a modified gold electrode.

  European journal of biochemistry 20030201

• Crystallization and preliminary X-ray analysis of NADP(H)-dependent alcohol dehydrogenases from Saccharomyces cerevisiae and Rana perezi.

  Acta crystallographica. Section D, Biological crystallography 20030201

• Expression, crystallization and activities of the two family 11 aldo-keto reductases from Bacillus subtilis.

  Acta crystallographica. Section D, Biological crystallography 20030201

• Activation of cytochrome P450 2C9-mediated metabolism: mechanistic evidence in support of kinetic observations.

  Archives of biochemistry and biophysics 20030201

• Vitamin C booster.

  Nature biotechnology 20030201

• Temperature and redox state dependence of native Kv2.1 currents in rat pancreatic beta-cells.

  The Journal of physiology 20030201

• Analysis of NAD(P)+/NAD(P)H cofactors by imprinted polymer membranes associated with ion-sensitive field-effect transistor devices and Au-quartz crystals.

  Analytical chemistry 20030201

• Metabolic activation of a pyrazinone-containing thrombin inhibitor. Evidence for novel biotransformation involving pyrazinone ring oxidation, rearrangement, and covalent binding to proteins.

  Chemical research in toxicology 20030201

• Cell-specific expression of NADPH-dependent cytosolic 3,5,3'-triiodo-L-thyronine-binding protein (p38CTBP).

  European journal of endocrinology 20030201

• Conformational changes and activation of yeast aldehyde dehydrogenase by various agents.

  Chemico-biological interactions 20030201

• Hydrogen bonding interactions between aldose reductase complexed with NADP(H) and inhibitor tolrestat studied by molecular dynamics simulations and binding assay.

  Chemico-biological interactions 20030201

• NADPH-dependent reductases and polyol formation in human leukemia cell lines.

  Chemico-biological interactions 20030201

• Examination of the differences in structure-function of human and rat 3alpha-hydroxysteroid dehydrogenase.

  Chemico-biological interactions 20030201

• Differential pyridine nucleotide coenzyme binding to the beta-subunit of the voltage-sensitive K+ channel: a mechanism for redox regulation of excitability?

  Chemico-biological interactions 20030201

• Expression pattern and biochemical characteristics of a major epidermal retinol dehydrogenase.

  Molecular genetics and metabolism 20030201

• Upregulation of NMDA receptor and neuronal NADPH-d/NOS expression in the nodose ganglion of acute hypoxic rats.

  Journal of chemical neuroanatomy 20030201

• Glutathione peroxidase activity and serum selenium concentration in intrinsic asthmatic patients.

  Clinical chemistry and laboratory medicine 20030201

• Purification and properties of glucose 6-phosphate dehydrogenase from turkey erythrocytes.

  Indian journal of biochemistry & biophysics 20030201

• Quantitative immunohistochemical investigation of the intrinsic vasodilator innervation of the guinea pig lingual artery.

  Autonomic neuroscience : basic & clinical 20030131

• Metabolic flux analysis of RQ-controlled microaerobic ethanol production by Saccharomyces cerevisiae.

  Yeast (Chichester, England) 20030130

• The ND5 subunit was labeled by a photoaffinity analogue of fenpyroximate in bovine mitochondrial complex I.

  Biochemistry 20030128

• Characterization of hydrogen peroxide removal reaction by hemoglobin in the presence of reduced pyridine nucleotides.

  Biochimica et biophysica acta 20030120

• Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis.

  Science (New York, N.Y.) 20030117

• Peroxynitrite protects neurons against nitric oxide-mediated apoptosis. A key role for glucose-6-phosphate dehydrogenase activity in neuroprotection.

  The Journal of biological chemistry 20030110

• Paraquat and menadione exposure of rainbow trout (Oncorhynchus mykiss)--studies of effects on the pentose-phosphate shunt and thiamine levels in liver and kidney.

  Chemico-biological interactions 20030106

• Inhibition of mammalian ribonucleases by endogenous adenosine dinucleotides.

  Biochemical and biophysical research communications 20030103

• Monitoring and kinetic study of ammonia oxidation using dissolved oxygen electrode and NAD(P) H fluorometer.

  Water research 20030101

• Characterization of native and recombinant A4 glyceraldehyde 3-phosphate dehydrogenase. Kinetic evidence for confromation changes upon association with the small protein CP12.

  European journal of biochemistry 20030101

• A structural basis for the mechanism of aspartate-beta-semialdehyde dehydrogenase from Vibrio cholerae.

  Protein science : a publication of the Protein Society 20030101

• Molecular characterization, function and regulation of ammonium transporters (Amt) and ammonium-metabolizing enzymes (GS, NADP-GDH) in the ectomycorrhizal fungus Hebeloma cylindrosporum.

  Molecular microbiology 20030101

• Role of specific cytochrome P450 enzymes in the N-oxidation of the antiarrhythmic agent mexiletine.

  Xenobiotica; the fate of foreign compounds in biological systems 20030101

• Formation of benzoquinol moiety in cornoside by salidroside mono-oxygenase, a cytochrome P450 enzyme, from Abeliophyllum distichumcell suspension cultures.

  Planta 20030101

• Characterization of two phases of chlorophyll formation during greening of etiolated barley leaves.

  Planta 20030101

• Abscisic acid, nitric oxide and stomatal closure - is nitrate reductase one of the missing links?

  Trends in plant science 20030101

• Aliphatic epoxide carboxylation.

  Annual review of biochemistry 20030101

• Mutagenic activation of arylamines by subcellular fractions of Chamaelea gallina clams exposed to environmental pollutants.

  Environmental and molecular mutagenesis 20030101

• Thermosensitive phenotype of Escherichia coli mutant lacking NADP+-dependent isocitrate dehydrogenase.

  Redox report : communications in free radical research 20030101

• Proposed mechanism for sperm chromatin condensation/decondensation in the male rat.

  Reproductive biology and endocrinology : RB&E 20030101

• Structural biology of the aldo-keto reductase family of enzymes: catalysis and cofactor binding.

  Cell biochemistry and biophysics 20030101

• Purification and properties of a NADPH-dependent erythrose reductase from the newly isolated Torula corallina.

  Biotechnology progress 20030101

• Involvement of thylakoid membranes in supramolecular organisation of Calvin cycle enzymes in Anacystis nidulans.

  Journal of plant physiology 20030101

• [Regulation of acetate metabolism in a strain of Acinetobacter sp., growing on ethanol].

  Prikladnaia biokhimiia i mikrobiologiia 20030101

• Coupling of neuronal activity and mitochondrial metabolism as revealed by NAD(P)H fluorescence signals in organotypic hippocampal slice cultures of the rat.

  Neuroscience 20030101

• Monitoring the growth and stress responses of yeast cells by two-dimensional fluorescence spectroscopy: first results.

  Folia microbiologica 20030101

• Inhibition studies of sulfonamide-containing folate analogs in yeast.

  Microbial drug resistance (Larchmont, N.Y.) 20030101

• Colorimetric dehydrogenase screen based on NAD(P)H generation.

  Methods in molecular biology (Clifton, N.J.) 20030101

• Starvation-induced impairment of metabolism in a freshwater catfish.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101

• Recombinant Plasmodium falciparum NADP-dependent isocitrate dehydrogenase is active and harbours a unique 26 amino acid tail.

  Experimental parasitology 20030101

• Synthesis of quaternised 2-aminopyrimido[4,5-d]pyrimidin-4(3H)-ones and their biological activity with dihydrofolate reductase.

  European journal of medicinal chemistry 20030101

• Glucose-6-phosphate dehydrogenase expression associated with NADPH-dependent reactions in cerebellar neurons.

  Cerebellum (London, England) 20030101

• [The activity of xylose reductase and xylitol dehydrogenase in yeasts].

  Mikrobiologiia 20030101

• [Biochemical characterization of the yeast Yarrowia lipolytica overproducing carboxylic acids from ethanol. Nitrogen metabolism enzymes].

  Mikrobiologiia 20030101

• Reductive metabolism of the nitroimidazole-based hypoxia-selective cytotoxin NLCQ-1 (NSC 709257).

  Oncology research 20030101

• Study of the mechanism of the cytostatic effect of picolinic acid on proliferating Tetrahymena pyriformis cells.

  Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20030101

• Pathophysiological aspects of cellular pyridine nucleotide metabolism: focus on the vascular endothelium. Review.

  Acta physiologica Hungarica 20030101

• Non-invasive glucose monitoring by NAD(P)H autofluorescence spectroscopy in fibroblasts and adipocytes: a model for skin glucose sensing.

  Diabetes technology & therapeutics 20030101

• Alpha-tocopherol and NADPH in the erythrocytes and plasma of multiple sclerosis patients. Effect of interferon-beta-1b treatment.

  European neurology 20030101

• Synthesis and studies of 1,2-dihydroquinoline derivatives as inhibitors of lipid peroxidation.

  Arzneimittel-Forschung 20030101

• [Ethomerzol as an antioxidant].

  Biomeditsinskaia khimiia 20030101

• Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.

  Biochemistry 20021231

• Structure of the MUR1 GDP-mannose 4,6-dehydratase from Arabidopsis thaliana: implications for ligand binding and specificity.

  Biochemistry 20021231

• Breaking symmetry: mutations engineered into R67 dihydrofolate reductase, a D2 symmetric homotetramer possessing a single active site pore.

  Biochemistry 20021231

• Organization of the avian basal forebrain: chemical anatomy in the parrot (Melopsittacus undulatus).

  The Journal of comparative neurology 20021223

• Suppression of interleukin-1 beta-induced nitric oxide production in RINm5F cells by inhibition of glucose-6-phosphate dehydrogenase.

  Biochemistry 20021217

• Methyl pyruvate stimulates pancreatic beta-cells by a direct effect on KATP channels, and not as a mitochondrial substrate.

  The Biochemical journal 20021215

• Pregnancy alters glucose-6-phosphate dehydrogenase trafficking, cell metabolism, and oxidant release of maternal neutrophils.

  The Journal of clinical investigation 20021215

• Nicotinic acid adenine dinucleotide phosphate mediates Ca2+ signals and contraction in arterial smooth muscle via a two-pool mechanism.

  Circulation research 20021213

• Electrical contacting of flavoenzymes and NAD(P)+-dependent enzymes by reconstitution and affinity interactions on phenylboronic acid monolayers associated with Au-electrodes.

  Journal of the American Chemical Society 20021211

• Identification of a magnesium-dependent NAD(P)(H)-binding domain in the nicotinoprotein methanol dehydrogenase from Bacillus methanolicus.

  The Journal of biological chemistry 20021206

• Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state.

  The Biochemical journal 20021201

• Enhancement of iron toxicity in L929 cells by D-glucose: accelerated(re-)reduction.

  The Biochemical journal 20021201

• Beta-amyloid inhibits NOS activity by subtracting NADPH availability.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021201

• Exposure of erythrocytes to methylene blue shows the active role of catalase in removing hydrogen peroxide.

  British journal of haematology 20021201

• Pyocyanin induces oxidative stress in human endothelial cells and modulates the glutathione redox cycle.

  Free radical biology & medicine 20021201

• The structures of Micrococcus lysodeikticus catalase, its ferryl intermediate (compound II) and NADPH complex.

  Acta crystallographica. Section D, Biological crystallography 20021201

• Free radical-mediated cell damage after experimental status epilepticus in hippocampal slice cultures.

  Journal of neurophysiology 20021201

• Structure of the monomeric isocitrate dehydrogenase: evidence of a protein monomerization by a domain duplication.

  Structure (London, England : 1993) 20021201

• Convergence of calcium signaling pathways of pathogenic elicitors and abscisic acid in Arabidopsis guard cells.

  Plant physiology 20021201

• Mechanism-based inactivation of cytochromes P450 2E1 and 2E1 T303A by tert-butyl acetylenes: characterization of reactive intermediate adducts to the heme and apoprotein.

  Chemical research in toxicology 20021201

• Ovarian modulators of 11beta-hydroxysteroid dehydrogenase (11betaHSD) activity in follicular fluid from gonadotrophin-stimulated assisted conception cycles.

  Reproduction (Cambridge, England) 20021201

• Lipid peroxidation-mediated cytotoxicity and DNA damage in U937 cells.

  Biochimie 20021201

• LPO and ethanol biotransformation systems in the liver as markers of predisposition to ethanol hepatotoxicity.

  Bulletin of experimental biology and medicine 20021201

• PqqC/D, which converts a biosynthetic intermediate to pyrroloquinoline quinone.

  Biochemical and biophysical research communications 20021129

• Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina.

  The Journal of biological chemistry 20021122

• The C-terminal extension of glyceraldehyde-3-phosphate dehydrogenase subunit B acts as an autoinhibitory domain regulated by thioredoxins and nicotinamide adenine dinucleotide.

  The Journal of biological chemistry 20021122

• Studies of the mechanism of phenol hydroxylase: effect of mutation of proline 364 to serine.

  Biochemistry 20021119

• Identification of the first fungal NADP-GAPDH from Kluyveromyces lactis.

  Biochemistry 20021119

• Amino acid substitution of arginine 80 in 17beta-hydroxysteroid dehydrogenase type 3 and its effect on NADPH cofactor binding and oxidation/reduction kinetics.

  Biochimica et biophysica acta 20021119

• Solubilization of receptors for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate.

  The Journal of biological chemistry 20021115

• Nifurtimox biotransformation to reactive metabolites or nitrite in liver subcellular fractions and model systems.

  Toxicology letters 20021115

• Cutting edge: fever-associated temperatures enhance neutrophil responses to lipopolysaccharide: a potential mechanism involving cell metabolism.

  Journal of immunology (Baltimore, Md. : 1950) 20021115

• Is reduction of the sulfonated tetrazolium 2,3-bis (2-methoxy-4-nitro-5-sulfophenyl)-2-tetrazolium 5-carboxanilide a reliable measure of intracellular superoxide production?

  Analytical biochemistry 20021115

• Differences in the efficiency of reductive activation of methionine synthase and exogenous electron acceptors between the common polymorphic variants of human methionine synthase reductase.

  Biochemistry 20021112

• Metabolic adaptation of Escherichia coli during temperature-induced recombinant protein production: 2. Redirection of metabolic fluxes.

  Biotechnology and bioengineering 20021105

• Xanthones as inhibitors of microsomal lipid peroxidation and TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs).

  Bioorganic & medicinal chemistry 20021101

• Inhibition of human cytochrome P450 activities by kava extract and kavalactones.

  Drug metabolism and disposition: the biological fate of chemicals 20021101

• The critical role of mitochondrial energetic impairment in the toxicity of nimesulide to hepatocytes.

  The Journal of pharmacology and experimental therapeutics 20021101

• Characterization of the dehydroepiandrosterone (DHEA) metabolism via oxysterol 7alpha-hydroxylase and 17-ketosteroid reductase activity in the human brain.

  Journal of neurochemistry 20021101

• Impaired ascorbic acid metabolism in streptozotocin-induced diabetic rats.

  Free radical biology & medicine 20021101

• Non-respiratory oxygen consumption pathways in anaerobically-grown Saccharomyces cerevisiae: evidence and partial characterization.

  Yeast (Chichester, England) 20021101

• Identification of human CYP forms involved in the activation of tamoxifen and irreversible binding to DNA.

  Carcinogenesis 20021101

• Characterization of a Saccharomyces cerevisiae NADP(H)-dependent alcohol dehydrogenase (ADHVII), a member of the cinnamyl alcohol dehydrogenase family.

  European journal of biochemistry 20021101

• Formation of pyridine nucleotides under symbiotic and non-symbiotic conditions between soybean nodules and free-living rhizobia.

  Phytochemistry 20021101

• Sterol regulatory element-binding proteins: transcriptional activators of lipid synthesis.

  Biochemical Society transactions 20021101

• Activated transformations of organophosphorus insecticides in the case of non-AChE inhibitory oxons.

  Pest management science 20021101

• Redox control by dithiol-disulfide exchange in plants: II. The cytosolic and mitochondrial systems.

  Annals of the New York Academy of Sciences 20021101

• In vitro biotransformation of 2,6,9-trisubstituted purine-derived cyclin-dependent kinase inhibitor bohemine by mouse liver microsomes.

  Xenobiotica; the fate of foreign compounds in biological systems 20021101

• Intestinal and hepatic microsomal metabolism of testosterone and progesterone by a 3 alpha-hydroxysteroid dehydrogenase to the 3 alpha-hydroxy derivatives in the channel catfish, Ictalurus punctatus.

  The Journal of steroid biochemistry and molecular biology 20021101

• Identification and characterization of SnrA, an inducible oxygen-insensitive nitroreductase in Salmonella enterica serovar Typhimurium TA1535.

  Mutation research 20021031

• Role of antioxidants in paraquat toxicity.

  Toxicology 20021030

• CYP119 plus a Sulfolobus tokodaii strain 7 ferredoxin and 2-oxoacid:ferredoxin oxidoreductase constitute a high-temperature cytochrome P450 catalytic system.

  Journal of the American Chemical Society 20021030

• Chemoarchitecture of GABAergic neurons in the ferret superior colliculus.

  The Journal of comparative neurology 20021028

• The role of tetrahydrobiopterin in the regulation of neuronal nitric-oxide synthase-generated superoxide.

  The Journal of biological chemistry 20021025

• Coupling interactions of distal residues enhance dihydrofolate reductase catalysis: mutational effects on hydride transfer rates.

  Biochemistry 20021022

• Nicotinic acid-adenine dinucleotide phosphate activates the skeletal muscle ryanodine receptor.

  The Biochemical journal 20021015

• Dynamic imaging of free cytosolic ATP concentration during fuel sensing by rat hypothalamic neurones: evidence for ATP-independent control of ATP-sensitive K(+) channels.

  The Journal of physiology 20021015

• Inactivation of human peroxiredoxin I during catalysis as the result of the oxidation of the catalytic site cysteine to cysteine-sulfinic acid.

  The Journal of biological chemistry 20021011

• Cytochrome P450 2E1 dependent catalytic activity and lipid peroxidation in rat blood lymphocytes.

  Life sciences 20021011

• GXXXG and GXXXA motifs stabilize FAD and NAD(P)-binding Rossmann folds through C(alpha)-H... O hydrogen bonds and van der waals interactions.

  Journal of molecular biology 20021011

• Identification of a novel human nicotinamide mononucleotide adenylyltransferase.

  Biochemical and biophysical research communications 20021004

• Stopped-flow kinetic studies of electron transfer in the reductase domain of neuronal nitric oxide synthase: re-evaluation of the kinetic mechanism reveals new enzyme intermediates and variation with cytochrome P450 reductase.

  The Biochemical journal 20021001

• A novel cycling assay for nicotinic acid-adenine dinucleotide phosphate with nanomolar sensitivity.

  The Biochemical journal 20021001

• Identification of cofactor discrimination sites in NAD-isocitrate dehydrogenase from Pyrococcus furiosus.

  Archives of microbiology 20021001

• Mechanisms of vanadate-induced cellular toxicity: role of cellular glutathione and NADPH.

  Archives of biochemistry and biophysics 20021001

• Reverse flux through cardiac NADP(+)-isocitrate dehydrogenase under normoxia and ischemia.

  American journal of physiology. Heart and circulatory physiology 20021001

• Pyruvate improves redox status and decreases indicators of hepatic apoptosis during hemorrhagic shock in swine.

  American journal of physiology. Heart and circulatory physiology 20021001

• Role of NADH shuttles in glucose-induced insulin secretion from fetal beta-cells.

  Diabetes 20021001

• Purification and kinetic analysis of the two recombinant arogenate dehydrogenase isoforms of Arabidopsis thaliana.

  European journal of biochemistry 20021001

• Nicotinic acid adenine dinucleotide phosphate (NAADP) is present at micromolar concentrations in sea urchin spermatozoa.

  The Journal of physiology 20021001

• Protection of sperm DNA against oxidative stress in vivo by accessory sex gland secretions in male hamsters.

  Reproduction (Cambridge, England) 20021001

• Inactivation of NADP(+)-dependent isocitrate dehydrogenase by nitric oxide.

  Free radical biology & medicine 20021001

• Probing the role of glutamic acid 139 of Anabaena ferredoxin-NADP+ reductase in the interaction with substrates.

  European journal of biochemistry 20021001

• Duodenal infusion of glucose decreases milk fat production in grass silage-fed dairy cows.

  Journal of dairy science 20021001

• [Mitochondria as the signal generator in the metabolism-secretion coupling in pancreatic beta cells].

  Nihon rinsho. Japanese journal of clinical medicine 20021001

• Mathematical modeling of in vitro enzymatic production of 2-Keto-L-gulonic acid using NAD(H) or NADP(H) as cofactors.

  Metabolic engineering 20021001

• Changes of pentose phosphate pathway flux in vivo in Corynebacterium glutamicum during leucine-limited batch cultivation as determined from intracellular metabolite concentration measurements.

  Metabolic engineering 20021001

• Copper, zinc superoxide dismutase and H2O2. Effects of bicarbonate on inactivation and oxidations of NADPH and urate, and on consumption of H2O2.

  The Journal of biological chemistry 20020920

• Stereoselective hydroxylation of 4-methyl-2-cyclohexenone in rats: its relevance to R-(+)-pulegone-mediated hepatotoxicity.

  Biochemical and biophysical research communications 20020920

• Modified carbon paste electrodes for flow injection amperometric determination of isocitrate dehydrogenase activity in serum.

  Analytical biochemistry 20020915

• Calmodulin activates electron transfer through neuronal nitric-oxide synthase reductase domain by releasing an NADPH-dependent conformational lock.

  The Journal of biological chemistry 20020913

• Oxidation of methoxyphenethylamines by cytochrome P450 2D6. Analysis of rate-limiting steps.

  The Journal of biological chemistry 20020913

• The B' helix determines cytochrome P450nor specificity for the electron donors NADH and NADPH.

  The Journal of biological chemistry 20020913

• Phosphite dehydrogenase: a versatile cofactor-regeneration enzyme.

  Angewandte Chemie (International ed. in English) 20020902

• NADPH-dependent GMP reductase isoenzyme of human (GMPR2). Expression, purification, and kinetic properties.

  The international journal of biochemistry & cell biology 20020901

• Neuronal activation of brain vagal-regulatory pathways and upper gut enteric plexuses by insulin hypoglycemia.

  American journal of physiology. Endocrinology and metabolism 20020901

• Ca(2+) modulates respiratory and steroidogenic activities of human term placental mitochondria.

  Archives of biochemistry and biophysics 20020901

• A structurally conserved water molecule in Rossmann dinucleotide-binding domains.

  Protein science : a publication of the Protein Society 20020901

• Analysis of quinazoline and pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase.

  Acta crystallographica. Section D, Biological crystallography 20020901

• Cell signalling and the glutathione redox system.

  Biochemical pharmacology 20020901

• Effect of iodine or iopanoic acid on thyroid Ca2+/NADPH-dependent H2O2-generating activity and thyroperoxidase in toxic diffuse goiters.

  European journal of endocrinology 20020901

• Loss of nuclear gene expression during the phytochrome A-mediated far-red block of greening response.

  Plant physiology 20020901

• Neonicotinoid insecticides: reduction and cleavage of imidacloprid nitroimine substituent by liver microsomal and cytosolic enzymes.

  Chemical research in toxicology 20020901

• Isoprenoid biosynthesis via the methylerythritol phosphate pathway. Mechanistic investigations of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase.

  European journal of biochemistry 20020901

• Redox-sensitive loops D and E regulate NADP(H) binding in domain III and domain I-domain III interactions in proton-translocating Escherichia coli transhydrogenase.

  European journal of biochemistry 20020901

• Rat and human liver cytochrome P-450 isoform metabolism of ecteinascidin 743 does not predict gender-dependent toxicity in humans.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020901

• Initial characterization of a type I fatty acid synthase and polyketide synthase multienzyme complex NorS in the biosynthesis of aflatoxin B(1).

  Chemistry & biology 20020901

• [SNP collection, pharmacogenomics, and the future of drug therapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20020901

• NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH.

  Journal of biomolecular NMR 20020901

• Pancreatic islet beta-cells transiently metabolize pyruvate.

  The Journal of biological chemistry 20020823

• Lipoyl dehydrogenase catalyzes reduction of nitrated DNA and protein adducts using dihydrolipoic acid or ubiquinol as the cofactor.

  Chemico-biological interactions 20020815

• Metabolism of biochanin A and formononetin by human liver microsomes in vitro.

  Journal of agricultural and food chemistry 20020814

• Deoxysarpagine hydroxylase--a novel enzyme closing a short side pathway of alkaloid biosynthesis in Rauvolfia.

  Bioorganic & medicinal chemistry 20020801

• Stretch-induced Ca(2+) release via an IP(3)-insensitive Ca(2+) channel.

  American journal of physiology. Cell physiology 20020801

• Increased glucose sensitivity of stimulus-secretion coupling in islets from Psammomys obesus after diet induction of diabetes.

  Diabetes 20020801

• Inhibition of oxidative stress produced by plasma membrane NADH oxidase delays low-potassium-induced apoptosis of cerebellar granule cells.

  Journal of neurochemistry 20020801

• Structure of methylene-tetrahydromethanopterin dehydrogenase from methylobacterium extorquens AM1.

  Structure (London, England : 1993) 20020801

• Expression, purification, and characterization of recombinant nonphosphorylating NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Clostridium acetobutylicum.

  Protein expression and purification 20020801

• [Molecular toxicological mechanism of the lethal interactions of the new antiviral drug, sorivudine, with 5-fluorouracil prodrugs and genetic deficiency of dihydropyrimidine dehydrogenase].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020801

• Site-directed mutagenesis of Tyr-189 and Lys-193 in NADPH: protochlorophyllide oxidoreductase from Synechocystis.

  Biochemical Society transactions 20020801

• Role of membrane-associated Ca+ dependent matrix metalloprotease-2 in the oxidant activation of Ca2+Atpase by tertiary butylhydroperoxide.

  Molecular and cellular biochemistry 20020801

• Metabolism of 2-nitrofluorene, an environmental pollutant, by liver preparations of sea bream, Pagrus major.

  Xenobiotica; the fate of foreign compounds in biological systems 20020801

• Differential role of CYP2E1 binders and isoniazid on CYP2E1 protein modification in NADPH-dependent microsomal oxidative reactions: free radical scavenging ability of isoniazid.

  Free radical research 20020801

• Biochemical and molecular properties of the cytochrome P450 arachidonic acid monooxygenases.

  Prostaglandins & other lipid mediators 20020801

• Oxidative status and distribution of NADP-dependent isocitrate dehydrogenase and aconitate hydratase in rat cardiomyocytes under normal conditions and during ischemia.

  Bulletin of experimental biology and medicine 20020801

• Recombinant squalene synthase. Synthesis of non-head-to-tail isoprenoids in the absence of NADPH.

  Journal of the American Chemical Society 20020731

• Recombinant squalene synthase. A mechanism for the rearrangement of presqualene diphosphate to squalene.

  Journal of the American Chemical Society 20020731

• First non-alpha-amino acid guanidines acting as efficient NO precursors upon oxidation by NO-synthase II or activated mouse macrophages.

  Biochemistry 20020730

• Differential effect of copper (II) on the cytochrome P450 enzymes and NADPH-cytochrome P450 reductase: inhibition of cytochrome P450-catalyzed reactions by copper (II) ion.

  Biochemistry 20020730

• Effect of luminal and extravesicular Ca2+ on NAADP binding and release properties.

  Biochemical and biophysical research communications 20020726

• Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice.

  Circulation research 20020726

• Acute alcohol intoxication decreases cell proliferation and nitric oxide synthase expression in dentate gyrus of rats.

  Toxicology letters 20020721

• A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase.

  Biochemistry 20020716

• Chemical formation of 4-hydroxy-2,5-dimethyl-3[2H]-furanone from D-fructose 1,6-diphosphate.

  Carbohydrate research 20020716

• Lactate -- the forgotten fuel!

  The Journal of physiology 20020715

• Atomic structures of human dihydrofolate reductase complexed with NADPH and two lipophilic antifolates at 1.09 a and 1.05 a resolution.

  Journal of molecular biology 20020712

• Increased NADPH oxidase activity, gp91phox expression, and endothelium-dependent vasorelaxation during neointima formation in rabbits.

  Circulation research 20020712

• Metabolism of the novel Ca2+-mobilizing messenger nicotinic acid-adenine dinucleotide phosphate via a 2'-specific Ca2+-dependent phosphatase.

  The Biochemical journal 20020701

• Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020701

• Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells.

  Free radical biology & medicine 20020701

• Occurrence of a novel NADP(+)-linked alcohol dehydrogenase in Euglena gracilis.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020701

• Poly(ADP-ribose) polymerase inhibition prevents both apoptotic-like delayed neuronal death and necrosis after H(2)O(2) injury.

  Journal of neurochemistry 20020701

• Nitrate regulation of alpha-aminoadipate reductase formation and lysine inhibition of its activity in Penicillium chrysogenum and Acremonium chrysogenum.

  Applied microbiology and biotechnology 20020701

• Two mechanisms for oxidation of cytosolic NADPH by Kluyveromyces lactis mitochondria.

  Yeast (Chichester, England) 20020701

• Dinitrobenzene-mediated production of peroxynitrite by neuronal nitric oxide synthase.

  Chemical research in toxicology 20020701

• Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of alpha-naphthylisothiocyanate.

  Toxicology and applied pharmacology 20020701

• Recombinant human glucose-6-phosphate dehydrogenase. Evidence for a rapid-equilibrium random-order mechanism.

  European journal of biochemistry 20020701

• Impairment of autoregulatory vasodilation by NAD(P)H oxidase-dependent superoxide generation during acute stage of subarachnoid hemorrhage in rat pial artery.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020701

• Synthesis and antioxidative properties of novel thiazolidinedione/imidazolidinedione compounds as retinoids.

  Die Pharmazie 20020701

• Rhythmic activity from transverse brainstem slice of neonatal rat is modulated by nitric oxide.

  Neuropharmacology 20020701

• Properties of the recombinant ferredoxin-dependent glutamate synthase of Synechocystis PCC6803. Comparison with the Azospirillum brasilense NADPH-dependent enzyme and its isolated alpha subunit.

  Biochemistry 20020625

• Catalytic mechanism of S-adenosylhomocysteine hydrolase. Site-directed mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190.

  The Journal of biological chemistry 20020621

• Purification, reconstitution, and steady-state kinetics of the trans-membrane 17 beta-hydroxysteroid dehydrogenase 2.

  The Journal of biological chemistry 20020621

• Tumor necrosis factor-alpha increases airway smooth muscle oxidants production through a NADPH oxidase-like system to enhance myosin light chain phosphorylation and contractility.

  The Journal of biological chemistry 20020621

• Anabaena sp. PCC 7119 flavodoxin as electron carrier from photosystem I to ferredoxin-NADP+ reductase. Role of Trp(57) and Tyr(94).

  The Journal of biological chemistry 20020621

• Mutational analysis of human thioredoxin reductase 1. Effects on p53-mediated gene expression and interferon and retinoic acid-induced cell death.

  The Journal of biological chemistry 20020621

• Mechanism of coenzyme recognition and binding revealed by crystal structure analysis of ferredoxin-NADP+ reductase complexed with NADP+.

  Journal of molecular biology 20020621

• Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex.

  Journal of molecular biology 20020621

• Nitroxyl (NO-): a substrate for superoxide dismutase.

  Archives of biochemistry and biophysics 20020615

• Mitochondrial superoxide production during oxalate-mediated oxidative stress in renal epithelial cells.

  Free radical biology & medicine 20020615

• Limitation to photosynthesis in water-stressed leaves: stomata vs. metabolism and the role of ATP.

  Annals of botany 20020615

• Kinetic and structural basis of reactivity of pentaerythritol tetranitrate reductase with NADPH, 2-cyclohexenone, nitroesters, and nitroaromatic explosives.

  The Journal of biological chemistry 20020614

• Electrochemical and peroxidase oxidation study of N'-hydroxyguanidine derivatives as NO donors.

  Bioorganic & medicinal chemistry letters 20020603

• Vomilenine reductase--a novel enzyme catalyzing a crucial step in the biosynthesis of the therapeutically applied antiarrhythmic alkaloid ajmaline.

  Bioorganic & medicinal chemistry 20020601

• Glutathione and K(+) channel remodeling in postinfarction rat heart.

  American journal of physiology. Heart and circulatory physiology 20020601

• Role of water in the catalytic cycle of E. coli dihydrofolate reductase.

  Protein science : a publication of the Protein Society 20020601

• Metabolic control of resistance of human epithelial cells to H2O2 and NO stresses.

  The Biochemical journal 20020601

• Inhibition of mesangial iNOS by reduced extracellular pH is associated with uncoupling of NADPH oxidation.

  Kidney international 20020601

• 5,10-Methylenetetrahydrofolate reductase (MTHFR) assay in the forward direction: residual activity in MTHFR deficiency.

  Clinical chemistry 20020601

• Cytosolic NADP(+)-dependent isocitrate dehydrogenase status modulates oxidative damage to cells.

  Free radical biology & medicine 20020601

• Disruption of the NAD(P)H:quinone oxidoreductase 1 (NQO1) gene in mice causes myelogenous hyperplasia.

  Cancer research 20020601

• Structure-based enzyme inhibitor design: modeling studies and crystal structure analysis of Pneumocystis carinii dihydrofolate reductase ternary complex with PT653 and NADPH.

  Acta crystallographica. Section D, Biological crystallography 20020601

• Apoptosis in mitotic competent undifferentiated cells is induced by cellular redox imbalance independent of reactive oxygen species production.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020601

• Epiandrosterone, a metabolite of testosterone precursor, blocks L-type calcium channels of ventricular myocytes and inhibits myocardial contractility.

  Journal of molecular and cellular cardiology 20020601

• Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode.

  Structure (London, England : 1993) 20020601

• Reactive oxygen species generated by PAH o-quinones cause change-in-function mutations in p53.

  Chemical research in toxicology 20020601

• 2-Amino-3-carboxy-1,4-naphthoquinone affects the end-product profile of bifidobacteria through the mediated oxidation of NAD(P)H.

  Applied microbiology and biotechnology 20020601

• Decreased redox state in red blood cells from patients with sarcoidosis.

  Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 20020601

• Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats.

  Bioscience, biotechnology, and biochemistry 20020601

• Sulfo-SADP (sulfosuccinimidyl[4-azidophenyldithio]propionate) an active site directed reagent inhibiting the NADPH dependent O2- generation of leukocyte cytochrome b(558).

  Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) 20020601

• Substrate specificity of mammalian pyridine nucleotide transglycosidases.

  Journal of nutritional science and vitaminology 20020601

• Synthesis of pyridine nucleotide analogs consisting of nicotinoylamino acids by means of transglycosidation reactions catalyzed by mammalian pyridine nucleotide transglycosidases.

  Journal of nutritional science and vitaminology 20020601

• A spectrophotometric method to monitor the catalytic activity of microsomal cytochrome P-450 IIB1/2: comparison with fluorometric assay.

  Indian journal of biochemistry & biophysics 20020601

• Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells.

  The Journal of biological chemistry 20020531

• A prenylated p67phox-Rac1 chimera elicits NADPH-dependent superoxide production by phagocyte membranes in the absence of an activator and of p47phox: conversion of a pagan NADPH oxidase to monotheism.

  The Journal of biological chemistry 20020524

• Quantification of the influence of HPrSer46P on CcpA-cre interaction.

  Journal of molecular biology 20020524

• Optimizing an artificial metabolic pathway: engineering the cofactor specificity of Corynebacterium 2,5-diketo-D-gluconic acid reductase for use in vitamin C biosynthesis.

  Biochemistry 20020521

• A phosphate-stimulated NAD(P)+-dependent glyceraldehyde-3-phosphate dehydrogenase in Bacillus cereus.

  FEMS microbiology letters 20020521

• Glutamate dehydrogenase of Halobacterium salinarum: evidence that the gene sequence currently assigned to the NADP+-dependent enzyme is in fact that of the NAD+-dependent glutamate dehydrogenase.

  FEMS microbiology letters 20020521

• Sequential inactivation of zeta-crystallin by o-phthalaldehyde.

  Biochimica et biophysica acta 20020520

• Purification and characterization of ferredoxin-NAD(P)(+) reductase from the green sulfur bacterium Chlorobium tepidum.

  Biochimica et biophysica acta 20020520

• Chemiluminescence associated with the oxidative metabolism of salicylic acid in rat liver microsomes.

  Chemico-biological interactions 20020520

• Cardiolipin prevents rate-dependent uncoupling and provides osmotic stability in yeast mitochondria.

  The Biochemical journal 20020515

• Interactions between the isolated oxygenase and reductase domains of neuronal nitric-oxide synthase: assessing the role of calmodulin.

  The Journal of biological chemistry 20020510

• Inhibition of gastric cancer cell proliferation by resveratrol: role of nitric oxide.

  American journal of physiology. Gastrointestinal and liver physiology 20020501

• Two-photon fluorescence spectroscopy and microscopy of NAD(P)H and flavoprotein.

  Biophysical journal 20020501

• Oxidative stress in a phenylketonuria animal model.

  Free radical biology & medicine 20020501

• The effects of low pH on the properties of protochlorophyllide oxidoreductase and the organization of prolamellar bodies of maize (Zea mays).

  European journal of biochemistry 20020501

• Nitric oxide and neuromodulation in the caudal neurosecretory system of teleosts.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020501

• Stimulatory effect of cigarette smoking on the 15 alpha-hydroxylation of estradiol by human term placenta.

  Clinical pharmacology and therapeutics 20020501

• Interactions between intracellular Ca2+ stores: Ca2+ released from the NAADP pool potentiates cADPR-induced Ca2+ release.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020501

• Chemiosmotic ATP synthesis in photosynthetically inactive chromoplasts from Narcissus pseudonarcissus L. linked to a redox pathway potentially also involved in carotene desaturation.

  Planta 20020501

• Comparative metabolism of N-tert-butyl-N-[1-(1-oxy-pyridin-4-yl)-ethyl]- and N-tert-butyl-N-(1-phenyl-ethyl)-nitroxide by the cytochrome P450 monooxygenase system.

  Chemical research in toxicology 20020501

• Cyclic ADP-ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP): novel regulators of Ca2+-signaling and cell function.

  Current molecular medicine 20020501

• Implication by site-directed mutagenesis of Arg314 and Tyr316 in the coenzyme site of pig mitochondrial NADP-dependent isocitrate dehydrogenase.

  Archives of biochemistry and biophysics 20020501

• Increased rate of cholesterologenesis--a possible cause of hypercholesterolemia in experimental chronic renal failure in rats.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020501

• Microsomal cytochrome P450 and eicosanoid metabolism.

  Cellular and molecular life sciences : CMLS 20020501

• Increased resistance to nitric oxide cytotoxicity associated with differentiation of neuroblastoma-glioma hybrid (NG108-15) cells.

  Free radical research 20020501

• Evaluation by mutagenesis of the roles of His309, His315, and His319 in the coenzyme site of pig heart NADP-dependent isocitrate dehydrogenase.

  Biochemistry 20020430

• Zeta-crystallin displays strong selectivity for salicylic acid over aspirin.

  Biochemical and biophysical research communications 20020426

• Development of an enzymatic method to quantify methyl ketones from bacterial origin.

  Journal of agricultural and food chemistry 20020424

• Comparison of SPE and fast LC to eliminate mass spectrometric matrix effects from microsomal incubation products.

  Journal of pharmaceutical and biomedical analysis 20020415

• Heat shock inactivates cellular antioxidant defenses against hydrogen peroxide: protection by glucose.

  Free radical biology & medicine 20020415

• Alteration of inhibitor selectivity by site-directed mutagenesis of Arg(294) in the ADP-glucose pyrophosphorylase from Anabaena PCC 7120.

  Archives of biochemistry and biophysics 20020415

• Crystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transfer.

  The Journal of biological chemistry 20020412

• Thermodynamic analysis of the emergence of new regulatory properties in a phosphoribulokinase-glyceraldehyde 3-phosphate dehydrogenase complex.

  The Journal of biological chemistry 20020412

• Reduced nicotinamide nucleotides prevent nitration of tyrosine hydroxylase by peroxynitrite.

  Brain research 20020412

• Identification of lysine-78 as an essential residue in the Saccharomyces cerevisiae xylose reductase.

  FEMS microbiology letters 20020409

• Cell side-specific sensitivities of intracellular Ca2+ stores for inositol 1,4,5-trisphosphate, cyclic ADP-ribose, and nicotinic acid adenine dinucleotide phosphate in permeabilized pancreatic acinar cells from mouse.

  The Journal of biological chemistry 20020405

• Propionyl-coenzyme A synthase from Chloroflexus aurantiacus, a key enzyme of the 3-hydroxypropionate cycle for autotrophic CO2 fixation.

  The Journal of biological chemistry 20020405

• Synthesis and aldose reductase inhibitory activity of 5-arylidene-2,4-thiazolidinediones.

  Bioorganic & medicinal chemistry 20020401

• Reductive metabolism of an alpha,beta-ketoalkyne, 4-phenyl-3-butyn-2-one, by rat liver preparations.

  Drug metabolism and disposition: the biological fate of chemicals 20020401

• Mechanism-based inactivation of cytochrome P450 3A4 by 17 alpha-ethynylestradiol: evidence for heme destruction and covalent binding to protein.

  The Journal of pharmacology and experimental therapeutics 20020401

• Inhibitors of pentose phosphate pathway cause vasodilation: involvement of voltage-gated potassium channels.

  The Journal of pharmacology and experimental therapeutics 20020401

• Molecular and regulatory properties of leucoplast pyruvate kinase from Brassica napus (rapeseed) suspension cells.

  Archives of biochemistry and biophysics 20020401

• Nitrate reductase-formate dehydrogenase couple involved in the fungal denitrification by Fusarium oxysporum.

  Journal of biochemistry 20020401

• NAADP: an atypical Ca2+-release messenger?

  Trends in pharmacological sciences 20020401

• Evidence that hydroxyl radicals mediate auxin-induced extension growth.

  Planta 20020401

• Does nitric oxide act as a cellular messenger in muscarinic endometrial secretion in the guinea-pig?

  Acta physiologica Scandinavica 20020401

• Oxidative stress in human abdominal aortic aneurysms: a potential mediator of aneurysmal remodeling.

  Arteriosclerosis, thrombosis, and vascular biology 20020401

• A colorimetric assay to quantify dehydrogenase activity in crude cell lysates.

  Journal of biomolecular screening 20020401

• [Electron transfer flavoprotein in mitochondria].

  Nihon rinsho. Japanese journal of clinical medicine 20020401

• Use of kinetic isotope effects to delineate the role of phenylalanine 87 in P450(BM-3).

  Bioorganic chemistry 20020401

• Enzymes of malate metabolism in Mesorhizobium ciceri CC 1192.

  Canadian journal of microbiology 20020401

• Elucidation of the toxic mechanism of the plasticizers, phthalic acid esters, putative endocrine disrupters: effects of dietary di(2-ethylhexyl)phthalate on the metabolism of tryptophan to niacin in rats.

  Bioscience, biotechnology, and biochemistry 20020401

• Temperature dependence of kinetic parameters for hyperthermophilic glutamate dehydrogenase from Aeropyrum pernix K1.

  Bioscience, biotechnology, and biochemistry 20020401

• Biosynthesis of vitamin B6 in Rhizobium: in vitro synthesis of pyridoxine from 1-deoxy-D-xylulose and 4-hydroxy-L-threonine.

  Bioscience, biotechnology, and biochemistry 20020401

• Oxygen and glucose deprivation induces mitochondrial dysfunction and oxidative stress in neurones but not in astrocytes in primary culture.

  Journal of neurochemistry 20020401

• [Individual susceptibility to hematotoxicity from benzene exposure and the genetic polymorphism of metabolic enzymes].

  Wei sheng yan jiu = Journal of hygiene research 20020401

• Rat liver microsomal and nuclear activation of methanol to hydroxymethyl free radicals.

  Toxicology letters 20020328

• Involvement of NADPH in the cyclization reaction of carotenoid biosynthesis.

  FEBS letters 20020327

• Mutation in the glucose-6-phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress.

  The Journal of biological chemistry 20020322

• Effects of src-deficiency on the expression of in vivo toxicity of TCDD in a strain of c-src knockout mice procured through six generations of backcrossings to C57BL/6 mice.

  Toxicology 20020320

• Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling.

  Circulation research 20020308

• Bioaffinity purification of NADP(+)-dependent dehydrogenases: studies with alcohol dehydrogenase from Thermoanaerobacter brockii.

  Biotechnology and bioengineering 20020305

• The ferrireductase paraferritin contains divalent metal transporter as well as mobilferrin.

  American journal of physiology. Gastrointestinal and liver physiology 20020301

• Dog liver glucose-6-phosphate dehydrogenase: purification and kinetic properties.

  The international journal of biochemistry & cell biology 20020301

• Characterization by liquid chromatography-nuclear magnetic resonance spectroscopy and liquid chromatography-mass spectrometry of two coupled oxidative-conjugative metabolic pathways for 7-ethoxycoumarin in human liver microsomes treated with alamethicin.

  Drug metabolism and disposition: the biological fate of chemicals 20020301

• Time-dependent aromatase inactivation by 4 beta,5 beta-epoxides of the natural substrate androstenedione and its 19-oxygenated analogs.

  Steroids 20020301

• Glucose deprivation decreases nitric oxide production via NADPH depletion in immunostimulated rat primary astrocytes.

  Glia 20020301

• NADPH-dependent metabolism of estrone by human liver microsomes.

  The Journal of pharmacology and experimental therapeutics 20020301

• Overestimation of NADH-driven vascular oxidase activity due to lucigenin artifacts.

  Free radical biology & medicine 20020301

• The Antarctic Psychrobacter sp. TAD1 has two cold-active glutamate dehydrogenases with different cofactor specificities. Characterisation of the NAD+-dependent enzyme.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020301

• Transformation of local Ca2+ spikes to global Ca2+ transients: the combinatorial roles of multiple Ca2+ releasing messengers.

  The EMBO journal 20020301

• Role of mitochondrial permeability transition in diclofenac-induced hepatocyte injury in rats.

  Hepatology (Baltimore, Md.) 20020301

• Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase complexed with cofactors: implications of a flexible loop movement upon substrate binding.

  Journal of biochemistry 20020301

• Expression of NADP+-dependent 15-hydroxyprostaglandin dehydrogenase mRNA in monkey ocular tissues and characterization of its recombinant enzyme.

  Journal of biochemistry 20020301

• Multiple mechanisms in indomethacin-induced impairment of hepatic cytochrome P450 enzymes in rats.

  Gastroenterology 20020301

• A comparative analysis of translated dihydropyrimidine dehydrogenase cDNA; conservation of functional domains and relevance to genetic polymorphisms.

  Pharmacogenetics 20020301

• Red blood cell antioxidant and iron status in alcoholic and nonalcoholic cirrhosis.

  European journal of clinical investigation 20020301

• Microsomal activation of dibenzo[def,mno]chrysene (anthanthrene), a hexacyclic aromatic hydrocarbon without a bay-region, to mutagenic metabolites.

  Chemical research in toxicology 20020301

• 1,3-Dinitrobenzene metabolism and protein binding.

  Chemical research in toxicology 20020301

• 1,3-Dinitrobenzene metabolism and GSH depletion.

  Chemical research in toxicology 20020301

• [High throughput screening method of nitric oxide synthase inhibitors and enhancers].

  Yao xue xue bao = Acta pharmaceutica Sinica 20020301

• Expression and activity of nitric oxide synthase isoforms in rat brain during the development of experimental allergic encephalomyelitis.

  Brain research. Molecular brain research 20020227

• Regression of atherosclerosis in monkeys reduces vascular superoxide levels.

  Circulation research 20020222

• Crystallographic studies on human BST-1/CD157 with ADP-ribosyl cyclase and NAD glycohydrolase activities.

  Journal of molecular biology 20020222

• Biphasic oxidation of mitochondrial NAD(P)H.

  Biochemical and biophysical research communications 20020215

• Role of ATP decrease in secretion induced by mitochondrial dysfunction in guinea-pig adrenal chromaffin cells.

  The Journal of physiology 20020215

• Bilirubin and uroporphyrinogen oxidation by induced cytochrome P4501A and cytochrome P4502B. Role of polyhalogenated biphenyls of different configuration.

  Biochemical pharmacology 20020215

• N-Aryl N'-hydroxyguanidines, a new class of NO-donors after selective oxidation by nitric oxide synthases: structure-activity relationship.

  Journal of medicinal chemistry 20020214

• A novel approach to study the activity and stoichiometry simultaneously for microsomal pentoxyresorufin-O-dealkylase reaction.

  FEBS letters 20020213

• Metabolic engineering in yeast demonstrates that S-adenosylmethionine controls flux through the methylenetetrahydrofolate reductase reaction in vivo.

  The Journal of biological chemistry 20020208

• Effects of NADH and NADPH on superoxide levels and cerebral vascular tone.

  American journal of physiology. Heart and circulatory physiology 20020201

• Structural studies of the pigeon cytosolic NADP(+)-dependent malic enzyme.

  Protein science : a publication of the Protein Society 20020201

• Modulation of the reactivity of the essential cysteine residue of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa.

  The Biochemical journal 20020201

• Bisubstrate kinetics using SAS computer software.

  Analytical biochemistry 20020201

• Protein denitration/modification by Escherichia coli nitrate reductase and mammalian cytochrome P-450 reductase.

  Frontiers in bioscience : a journal and virtual library 20020201

• Variability in glucose transporter-1 levels and hexokinase activity in human melanoma.

  Melanoma research 20020201

• Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species.

  Arthritis and rheumatism 20020201

• Small changes in the activity of chloroplastic NADP(+)-dependent ferredoxin oxidoreductase lead to impaired plant growth and restrict photosynthetic activity of transgenic tobacco plants.

  The Plant journal : for cell and molecular biology 20020201

• Kinetic study of sn-glycerol-1-phosphate dehydrogenase from the aerobic hyperthermophilic archaeon, Aeropyrum pernix K1.

  European journal of biochemistry 20020201

• Inhibition of CYP3A-mediated oxidation in human hepatic microsomes by the dietary derived complex phenol, gallic acid.

  The Journal of pharmacy and pharmacology 20020201

• Modulation of apoptosis by mitochondrial uncouplers: apoptosis-delaying features despite intrinsic cytotoxicity.

  Biochemical pharmacology 20020201

• Glucose-6-phosphate dehydrogenase: a candidate gene for diabetes.

  Diabetic medicine : a journal of the British Diabetic Association 20020201

• Alteration of the specificity of the cofactor-binding pocket of Corynebacterium 2,5-diketo-D-gluconic acid reductase A.

  Protein engineering 20020201

• Isolation and characterization of tightly coupled mitochondria from wild type and nap mutant Neurospora crassa.

  Biochemistry. Biokhimiia 20020201

• Mitochondria respond to Ca2+ already in the submicromolar range: correlation with redox state.

  Cell calcium 20020201

• Preferential inhibition of the plasma membrane NADH oxidase (NOX) activity by diphenyleneiodonium chloride with NADPH as donor.

  Antioxidants & redox signaling 20020201

• Inactivation of maize NADP-malic enzyme by Cu2+-ascorbate.

  Indian journal of biochemistry & biophysics 20020201

• Mutational analysis of sites in sepiapterin reductase phosphorylated by Ca2+/calmodulin-dependent protein kinase II.

  Biochimica et biophysica acta 20020131

• Exploring the active site of plant glutaredoxin by site-directed mutagenesis.

  FEBS letters 20020130

• Photosystem I activity is increased in the absence of the PSI-G subunit.

  The Journal of biological chemistry 20020125

• Ca(2+) response to cADPr during maturation and fertilization of starfish oocytes.

  Biochemical and biophysical research communications 20020125

• Kinetic properties and inhibition of Trypanosoma cruzi 3-hydroxy-3-methylglutaryl CoA reductase.

  FEBS letters 20020116

• Degradation of L-glutamate dehydrogenase from Escherichia coli: allosteric regulation of enzyme stability.

  Archives of biochemistry and biophysics 20020115

• Perferryl complex of nitric oxide synthase: role in secondary free radical formation.

  Biochimica et biophysica acta 20020115

• Fluorescence imaging of metabolic responses in single mitochondria.

  Biochemical and biophysical research communications 20020111

• Biosynthesis of beta-substituted furan skeleton in the lower furanoterpenoids: a model study.

  Biochemical and biophysical research communications 20020111

• Highly divergent dihydrofolate reductases conserve complex folding mechanisms.

  Journal of molecular biology 20020111

• Neuronal nitric oxide synthase: substrate and solvent kinetic isotope effects on the steady-state kinetic parameters for the reduction of 2,6-dichloroindophenol and cytochrome c(3+).

  Biochemistry 20020108

• Effects of Ca(2+)-activated calmodulin on neuronal nitric oxide synthase reductase activity and binding of substrates: pH dependence of kinetic parameters.

  Biochemistry 20020108

• E. coli MEP synthase: steady-state kinetic analysis and substrate binding.

  Biochemistry 20020108

• Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice.

  The Journal of biological chemistry 20020104

• A study on permeability transition pore opening and cytochrome c release from mitochondria, induced by caspase-3 in vitro.

  FEBS letters 20020102

• Inhibition of camel lens zeta-crystallin by aspirin and aspirin-like analgesics.

  The international journal of biochemistry & cell biology 20020101

• High throughput assay for cytochrome P450 BM3 for screening libraries of substrates and combinatorial mutants.

  Biosensors & bioelectronics 20020101

• Citrulline is not the major product using the standard 'NOS activity' assay on renal cortical homogenates.

  American journal of physiology. Regulatory, integrative and comparative physiology 20020101

• Ipso-substitution by cytochrome P450 with conversion of p-hydroxybenzene derivatives to hydroquinone: evidence for hydroperoxo-iron as the active oxygen species.

  Archives of biochemistry and biophysics 20020101

• Expression, crystallization and preliminary X-ray analysis of human and rabbit 20alpha-hydroxysteroid dehydrogenases in complex with NADP(H) and various steroid substrates.

  Acta crystallographica. Section D, Biological crystallography 20020101

• Development of a synchronous enzyme-reaction system for a highly sensitive enzyme immunoassay.

  Journal of biochemistry 20020101

• NAD(P)H regeneration is the key for heterolactic fermentation of hexoses in Oenococcus oeni.

  Microbiology (Reading, England) 20020101

• Differential mechanisms of Ca(2+) release from vascular smooth muscle cell microsomes.

  Experimental biology and medicine (Maywood, N.J.) 20020101

• Fluorescence spectroscopy as a biomarker in a cell culture and in a nonhuman primate model for ovarian cancer chemopreventive agents.

  Journal of biomedical optics 20020101

• Alcohol induction of liver nuclear ethanol and N-nitrosodimethylamine metabolism to reactive metabolites.

  Teratogenesis, carcinogenesis, and mutagenesis 20020101

• [Stability of glucose 6-phosphate dehydrogenase complexed with its substrate and/or cofactor in aqueous and micellar environment].

  Prikladnaia biokhimiia i mikrobiologiia 20020101

• Efficacy of turmeric on blood sugar and polyol pathway in diabetic albino rats.

  Plant foods for human nutrition (Dordrecht, Netherlands) 20020101

• Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes.

  European journal of clinical pharmacology 20020101

• Mitochondrial thioredoxin reductase and thiol status.

  Methods in enzymology 20020101

• Recycling of vitamin C by mammalian thioredoxin reductase.

  Methods in enzymology 20020101

• Thioredoxin, thioredoxin reductase, and thioredoxin peroxidase of malaria parasite Plasmodium falciparum.

  Methods in enzymology 20020101

• Human placenta thioredoxin reductase: preparation and inhibitor studies.

  Methods in enzymology 20020101

• Purification and identification of an Escherichia coli beta-keto ester reductase as 2,5-diketo-D-gluconate reductase YqhE.

  Biotechnology progress 20020101

• An efficient enzymatic Baeyer-Villiger oxidation by engineered Escherichia coli cells under non-growing conditions.

  Biotechnology progress 20020101

• Purification and characterization of a microbial dehydrogenase: a vanillin:NAD(P)+ oxidoreductase.

  Applied biochemistry and biotechnology 20020101

• Functional evaluation of nonphagocytic NAD(P)H oxidases.

  Methods in enzymology 20020101

• Investigation of red blood cell carbonic anhydrase, glucose 6-phosphate dehydrogenase, hexokinase enzyme activities, and zinc concentration in patients with hyperthyroid diseases.

  Endocrine research 20020101

• Coupling of electrical and metabolic activity during epileptiform discharges.

  Epilepsia 20020101

• Functional imaging of mitochondrial redox state.

  Methods in enzymology 20020101

• Regulation of endothelial cell proliferation by nitric oxide.

  Methods in enzymology 20020101

• Cell death and metabolic activity during epileptiform discharges and status epilepticus in the hippocampus.

  Progress in brain research 20020101

• Pyridine nucleotide redox potential in erythrocytes of saudi subjects with sickle cell disease.

  Acta haematologica 20020101

• Marker enzyme assessment in the liver of cyprinus carpio (L.) exposed to 2,4-D and azinphosmethyl.

  Journal of biochemical and molecular toxicology 20020101

• Metabolic activation of adriamycin by NADPH-cytochrome P450 reductase; overview of its biological and biochemical effects.

  Acta biochimica Polonica 20020101

• Distribution of NADPH-diaphorase/nitric oxide synthase in the brain of the caecilian Dermophis mexicanus (amphibia: gymnophiona): comparative aspects in amphibians.

  Brain, behavior and evolution 20020101

• [New approaches to antioxidant therapy in multiple sclerosis].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101

• NAD(P)H:quinone reductase activity in human epidermal keratinocytes and reconstructed epidermal models.

  Skin pharmacology and applied skin physiology 20020101

• Vibrational structure of dihydrofolate bound to R67 dihydrofolate reductase.

  The Journal of biological chemistry 20011228

• Differences in three kinetic parameters underpin the unique catalytic profiles of nitric-oxide synthases I, II, and III.

  The Journal of biological chemistry 20011228

• Mitochondrial injury by disulfiram: two different mechanisms of the mitochondrial permeability transition.

  Chemico-biological interactions 20011221

• Critical role of the neuronal nitric-oxide synthase heme proximal side residue, Arg418, in catalysis and electron transfer.

  Journal of inorganic biochemistry 20011215

• Active site analysis of the potential antimicrobial target aspartate semialdehyde dehydrogenase.

  Biochemistry 20011204

• Crystal structure of Escherichia coli ketopantoate reductase at 1.7 A resolution and insight into the enzyme mechanism.

  Biochemistry 20011204

• Biochemical and crystallographic characterization of ferredoxin-NADP(+) reductase from nonphotosynthetic tissues.

  Biochemistry 20011204

• Structures of F420H2:NADP+ oxidoreductase with and without its substrates bound.

  The EMBO journal 20011203

• Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2.

  The Journal of pharmacology and experimental therapeutics 20011201

• Functional coupling of FcgammaRI to nicotinamide adenine dinucleotide phosphate (reduced form) oxidative burst and immune complex trafficking requires the activation of phospholipase D1.

  Blood 20011201

• Reactive oxygen species and cell signaling.

  American journal of respiratory cell and molecular biology 20011201

• Geraniol dehydrogenase activity related to aroma formation in ginger (Zingiber officinale Roscoe).

  Journal of agricultural and food chemistry 20011201

• The natural substrate for nitric oxide synthase activity.

  Cell biochemistry and function 20011201

• Oxidative stress in Ca(2+)-induced membrane permeability transition in brain mitochondria.

  Journal of neurochemistry 20011201

• Characterization of pyridine nucleotide coenzymes in the hyperthermophilic archaeon Pyrococcus furiosus.

  Extremophiles : life under extreme conditions 20011201

• Deoxypodophyllotoxin 6-hydroxylase, a cytochrome P450 monooxygenase from cell cultures of Linum flavum involved in the biosynthesis of cytotoxic lignans.

  Planta 20011201

• Cold acclimation of Arabidopsis thaliana results in incomplete recovery of photosynthetic capacity, associated with an increased reduction of the chloroplast stroma.

  Planta 20011201

• GSH is required to recycle ascorbic acid in cultured liver cell lines.

  Antioxidants & redox signaling 20011201

• The use of calcium blockers to study biochemical behaviour of Saccharomyces cerevisiae cells.

  Molecular and cellular biochemistry 20011201

• Brain oxidative stress--analytical chemistry and thermodynamics of glutathione and NADPH.

  Current topics in medicinal chemistry 20011201

• Relaxation of canine gallbladder to nerve stimulation involves adrenergic and non-adrenergic non-cholinergic mechanisms.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20011201

• Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins.

  The Journal of biological chemistry 20011130

• Involvement of the flavin si-face tyrosine on the structure and function of ferredoxin-NADP+ reductases.

  The Journal of biological chemistry 20011130

• Fast hydride transfer in proton-translocating transhydrogenase revealed in a rapid mixing continuous flow device.

  The Journal of biological chemistry 20011130

• Crystal structure of the non-regulatory A(4 )isoform of spinach chloroplast glyceraldehyde-3-phosphate dehydrogenase complexed with NADP.

  Journal of molecular biology 20011130

• NADP-glutamate dehydrogenase isoenzymes of Saccharomyces cerevisiae. Purification, kinetic properties, and physiological roles.

  The Journal of biological chemistry 20011123

• Spectroscopic and kinetic characterization of the bifunctional chorismate synthase from Neurospora crassa: evidence for a common binding site for 5-enolpyruvylshikimate 3-phosphate and NADPH.

  The Journal of biological chemistry 20011116

• Green tea epigallocatechin gallate: a natural inhibitor of fatty-acid synthase.

  Biochemical and biophysical research communications 20011116

• Interaction of camel lens zeta-crystallin with quinones: portrait of a substrate by fluorescence spectroscopy.

  Archives of biochemistry and biophysics 20011115

• Redox cycling by motexafin gadolinium enhances cellular response to ionizing radiation by forming reactive oxygen species.

  International journal of radiation oncology, biology, physics 20011115

• Formation of a tyrosyl radical intermediate in Proteus mirabilis catalase by directed mutagenesis and consequences for nucleotide reactivity.

  Biochemistry 20011113

• Metabolic flux response to phosphoglucose isomerase knock-out in Escherichia coli and impact of overexpression of the soluble transhydrogenase UdhA.

  FEMS microbiology letters 20011113

• NADH dehydrogenase of Corynebacterium glutamicum. Purification of an NADH dehydrogenase II homolog able to oxidize NADPH.

  FEMS microbiology letters 20011113

• Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution.

  The Journal of biological chemistry 20011109

• Antioxidative function and substrate specificity of NAD(P)H-dependent alkenal/one oxidoreductase. A new role for leukotriene B4 12-hydroxydehydrogenase/15-oxoprostaglandin 13-reductase.

  The Journal of biological chemistry 20011102

• Inactivation of cytochrome P450 by the food-derived complex phenol oleuropein.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20011101

• Chemical synthesis of 16beta-propylaminoacyl derivatives of estradiol and their inhibitory potency on type 1 17beta-hydroxysteroid dehydrogenase and binding affinity on steroid receptors.

  Steroids 20011101

• Unfolding and refolding of a quinone oxidoreductase: alpha-crystallin, a molecular chaperone, assists its reactivation.

  The Biochemical journal 20011101

• 8-dimethylallylnaringenin 2'-hydroxylase, the crucial cytochrome P450 mono-oxygenase for lavandulylated flavanone formation in Sophora flavescens cultured cells.

  Phytochemistry 20011101

• Characterization of hydride transfer to flavin adenine dinucleotide in neuronal nitric oxide synthase reductase domain: geometric relationship between the nicotinamide and isoalloxazine rings.

  Archives of biochemistry and biophysics 20011101

• Expression, purification, crystallization and preliminary crystallographic analysis of recombinant pteridine reductase of Trypanosoma cruzi.

  Acta crystallographica. Section D, Biological crystallography 20011101

• Critical residues for the specificity of cofactors and substrates in human estrogenic 17beta-hydroxysteroid dehydrogenase 1: variants designed from the three-dimensional structure of the enzyme.

  Molecular endocrinology (Baltimore, Md.) 20011101

• Interleukin-12 prevents diaphragm muscle deterioration in a septic animal model.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20011101

• Abscisic acid activation of plasma membrane Ca(2+) channels in guard cells requires cytosolic NAD(P)H and is differentially disrupted upstream and downstream of reactive oxygen species production in abi1-1 and abi2-1 protein phosphatase 2C mutants.

  The Plant cell 20011101

• Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices.

  Journal of pineal research 20011101

• Metabolism of tirapazamine by multiple reductases in the nucleus.

  Biochemical pharmacology 20011101

• Screening botanical extracts for quinoid metabolites.

  Chemical research in toxicology 20011101

• Ryanodine-, IP3- and NAADP-dependent calcium stores control acetylcholine release.

  Pflugers Archiv : European journal of physiology 20011101

• Effect of selenolipoic acid on peroxynitrite-dependent inactivation of NADPH-cytochrome P450 reductase.

  Free radical research 20011101

• Microspectrofluorometry of autofluorescence emission from human leukemic living cells under oxidative stress.

  Biology of the cell 20011101

• Changes of pyridine nucleotide levels during adipocyte differentiation of mouse 3T3-L1 cells.

  Bioscience, biotechnology, and biochemistry 20011101

• One site fits both: a model for the ternary complex of folate + NADPH in R67 dihydrofolate reductase, a D2 symmetric enzyme.

  Journal of computer-aided molecular design 20011101

• Self-powered enzyme-based biosensors.

  Journal of the American Chemical Society 20011031

• Structure of beta-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: negative cooperativity and its structural basis.

  Biochemistry 20011030

• Tyr275 and Lys279 stabilize NADPH within the catalytic site of NADPH:protochlorophyllide oxidoreductase and are involved in the formation of the enzyme photoactive state.

  Biochemistry 20011023

• Studies of the mechanism of phenol hydroxylase: mutants Tyr289Phe, Asp54Asn, and Arg281Met.

  Biochemistry 20011016

• The mechanism of dienoyl-CoA reduction by 2,4-dienoyl-CoA reductase is stepwise: observation of a dienolate intermediate.

  Biochemistry 20011016

• Cytochrome P450 2B (CYP2B)-mediated activation of methyl-parathion in rat brain extracts.

  Toxicology letters 20011015

• Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase.

  Circulation research 20011012

• An efficient chemoenzymatic strategy for the synthesis of wild-type and vancomycin-resistant bacterial cell-wall precursors: UDP-N-acetylmuramyl-peptides.

  Journal of the American Chemical Society 20011010

• Crystal structure of the FAD/NADPH-binding domain of rat neuronal nitric-oxide synthase. Comparisons with NADPH-cytochrome P450 oxidoreductase.

  The Journal of biological chemistry 20011005

• Metabolism of vitamin A affected by prostaglandin F synthase in contractile interstitial cells of bovine lung.

  Biochemical and biophysical research communications 20011005

• Mechanisms of ascorbic acid recycling in human erythrocytes.

  Biochimica et biophysica acta 20011003

• Mutations in the 3beta-hydroxysterol Delta24-reductase gene cause desmosterolosis, an autosomal recessive disorder of cholesterol biosynthesis.

  American journal of human genetics 20011001

• Inhibition of human cytochrome P450 aromatase activity by butyltins.

  Steroids 20011001

• Vitamin C and quinapril abrogate LVH and endothelial dysfunction in aortic-banded guinea pigs.

  American journal of physiology. Heart and circulatory physiology 20011001

• Nicotinic acid adenine dinucleotide phosphate enhances quantal neurosecretion at the frog neuromuscular junction: possible action on synaptic vesicles in the releasable pool.

  Molecular pharmacology 20011001

• A role for rubredoxin in oxidative stress protection in Desulfovibrio vulgaris: catalytic electron transfer to rubrerythrin and two-iron superoxide reductase.

  Archives of biochemistry and biophysics 20011001

• Analysis of reactive oxygen species generating systems in rat epididymal spermatozoa.

  Biology of reproduction 20011001

• Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor.

  The Journal of physiology 20011001

• Lack of effect of cADP-ribose and NAADP on the activity of skeletal muscle and heart ryanodine receptors.

  Cell calcium 20011001

• Phenylcoumaran benzylic ether and isoflavonoid reductases are a new class of cross-reactive allergens in birch pollen, fruits and vegetables.

  European journal of biochemistry 20011001

• NAADP+ initiates the Ca2+ response during fertilization of starfish oocytes.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011001

• Inhibitory action of Oren-gedoku-to extract on enzymatic lipid peroxidation in rat liver microsomes.

  Biological & pharmaceutical bulletin 20011001

• Calcium channels in lymphocytes.

  Immunology 20011001

• Proposed reductive metabolism of artemisinin by glutathione transferases in vitro.

  Free radical research 20011001

• Enzyme redesign.

  Chemical reviews 20011001

• Pyrimidine base catabolism in Pseudomonas putida biotype B.

  Antonie van Leeuwenhoek 20011001

• Reduced flavin: donor and acceptor enzymes and mechanisms of channeling.

  Antioxidants & redox signaling 20011001

• Structural and metabolic characteristic of nephrocytes during peritonitis of various genesis.

  Bulletin of experimental biology and medicine 20011001

• Copper,zinc superoxide dismutase as a univalent NO(-) oxidoreductase and as a dichlorofluorescin peroxidase.

  The Journal of biological chemistry 20010921

• Human methionine synthase reductase, a soluble P-450 reductase-like dual flavoprotein, is sufficient for NADPH-dependent methionine synthase activation.

  The Journal of biological chemistry 20010921

• Stabilization of noncovalent intermediates in enzymatically catalyzed reactions.

  Biochemical and biophysical research communications 20010921

• Simple and robust method for estimation of the split between the oxidative pentose phosphate pathway and the Embden-Meyerhof-Parnas pathway in microorganisms.

  Biotechnology and bioengineering 20010920

• EMDee: an enzymatic method for determining enantiomeric excess.

  Journal of the American Chemical Society 20010919

• Mechanistic studies of cyclohexanone monooxygenase: chemical properties of intermediates involved in catalysis.

  Biochemistry 20010918

• Antioxidant function of cytosolic sources of NADPH in yeast.

  Free radical biology & medicine 20010915

• Regulation of catalytic activity of a multifunctional polyketide biosynthetic enzyme, 6-hydroxymellein synthase, by interaction between NADPH and phenylglyoxal-sensitive amino acid residue at the reaction center.

  Biochimica et biophysica acta 20010910

• Hyperglycemia and cardiovascular disease.

  Current atherosclerosis reports 20010901

• Localization of cytosolic NADP-dependent isocitrate dehydrogenase in the peroxisomes of rat liver cells: biochemical and immunocytochemical studies.

  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20010901

• Calpains play a role in insulin secretion and action.

  Diabetes 20010901

• 7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures.

  Phytochemistry 20010901

• Ca(2+)/nicotinamide adenine dinucleotide phosphate-dependent H(2)O(2) generation is inhibited by iodide in human thyroids.

  The Journal of clinical endocrinology and metabolism 20010901

• Involvement of NADH/NADPH oxidase in human platelet ROS production.

  Thrombosis research 20010901

• Inactivation of rat cytochrome P450 2D enzyme by a further metabolite of 4-hydroxypropranolol, the major and active metabolite of propranolol.

  Biological & pharmaceutical bulletin 20010901

• [A simple and reliable spectrophotometric method for quantification of pyridine nucleotides in serum].

  Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20010901

• Enzymes in pancreatic islets that use NADP(H) as a cofactor including evidence for a plasma membrane aldehyde reductase.

  Molecular and cellular biochemistry 20010901

• X-Ray crystal structures of Candida albicans dihydrofolate reductase: high resolution ternary complexes in which the dihydronicotinamide moiety of NADPH is displaced by an inhibitor.

  Journal of medicinal chemistry 20010830

• Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate.

  Biochemistry 20010828

• Identification of a region involved in the communication between the NADP(H) binding domain and the membrane domain in proton pumping E. coli transhydrogenase.

  Biochemistry 20010821

• Oxidation of prostaglandin H(2) and prostaglandin H(2) analogues by human cytochromes P450: analysis of omega-side chain hydroxy metabolites and four steroisomers of 5-hydroxyprostaglandin I(1) by mass spectrometry.

  Biochemical pharmacology 20010815

• Attenuation of liver normothermic ischemia--reperfusion injury by preservation of mitochondrial functions with S-15176, a potent trimetazidine derivative.

  Biochemical pharmacology 20010815

• Adenine recognition: a motif present in ATP-, CoA-, NAD-, NADP-, and FAD-dependent proteins.

  Proteins 20010815

• Protochlorophyllide oxidoreductase: a homology model examined by site-directed mutagenesis.

  Proteins 20010815

• Potential involvement of several nitroreductases in metronidazole resistance in Helicobacter pylori.

  Archives of biochemistry and biophysics 20010815

• Vanadate-induced cell growth regulation and the role of reactive oxygen species.

  Archives of biochemistry and biophysics 20010815

• Activities and kinetic mechanisms of native and soluble NADPH-cytochrome P450 reductase.

  Biochemical and biophysical research communications 20010810

• NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer.

  The Journal of biological chemistry 20010803

• Structural studies on bioactive compounds. 34. Design, synthesis, and biological evaluation of triazenyl-substituted pyrimethamine inhibitors of Pneumocystis carinii dihydrofolate reductase.

  Journal of medicinal chemistry 20010802

• Carbohydrate deprivation reduces NADPH-production in fish liver but not in adipose tissue.

  The international journal of biochemistry & cell biology 20010801

• Oxidative pentose phosphate pathway and pyridine nucleotides in relation to heartwood formation in Robinia pseudoacacia L.

  Phytochemistry 20010801

• Ca(2+)-regulated nitric oxide generation in rabbit parotid acinar cells.

  Cell calcium 20010801

• Signaling by eNOS through a superoxide-dependent p42/44 mitogen-activated protein kinase pathway.

  American journal of physiology. Cell physiology 20010801

• Hypotonic swelling-induced Ca(2+) release by an IP(3)-insensitive Ca(2+) store.

  American journal of physiology. Cell physiology 20010801

• Contrasting effects of thiol-modulating agents on endothelial NO bioactivity.

  American journal of physiology. Cell physiology 20010801

• Characterization of the NADPH-dependent metabolism of 17beta-estradiol to multiple metabolites by human liver microsomes and selectively expressed human cytochrome P450 3A4 and 3A5.

  The Journal of pharmacology and experimental therapeutics 20010801

• Distinct pharmacology of 2-hydroxycarbazole-induced Ca2+ release in the sea urchin egg.

  The Journal of pharmacology and experimental therapeutics 20010801

• Extracellular glutathione inhibits oxygen-induced permeability changes in alveolar epithelial monolayers.

  Journal of applied physiology (Bethesda, Md. : 1985) 20010801

• Effect of alpha-methyldopa on pentoxyresorufin O-dealkylation in liver microsomes from rats treated with phenobarbital.

  Archives of biochemistry and biophysics 20010801

• Glucose-6-phosphate dehydrogenase deficiency promotes endothelial oxidant stress and decreases endothelial nitric oxide bioavailability.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010801

• Mutational study of the role of tyrosine-49 in the Saccharomyces cerevisiae xylose reductase.

  Yeast (Chichester, England) 20010801

• Oxidation of the ketoxime acetoxime to nitric oxide by oxygen radical-generating systems.

  Nitric oxide : biology and chemistry 20010801

• Molecular characterization of Escherichia coli NAD kinase.

  European journal of biochemistry 20010801

• Coordination of Ca2+ signalling by NAADP.

  Trends in biochemical sciences 20010801

• Does the activation of poly (ADP-ribose) synthetase mediate tissue injury in the sepsis induced by cecal ligation and puncture?

  Shock (Augusta, Ga.) 20010801

• In vitro immunosuppressive activity of tacrolimus dihydrodiol precursors obtained by chemical oxidation and identification of a new metabolite of SDZ-RAD by electrospray and electrospray-linked scan mass spectrometry.

  Journal of mass spectrometry : JMS 20010801

• Association of the NADPH:protochlorophyllide oxidoreductase (POR) with isolated etioplast inner membranes from wheat.

  The Plant journal : for cell and molecular biology 20010801

• Mitochondrial control of inducible nitric oxide production in stimulated RAW 264.7 macrophages.

  Antioxidants & redox signaling 20010801

• Xanthurenic acid inhibits metal ion-induced lipid peroxidation and protects NADP-isocitrate dehydrogenase from oxidative inactivation.

  Journal of nutritional science and vitaminology 20010801

• A structural account of substrate and inhibitor specificity differences between two naphthol reductases.

  Biochemistry 20010731

• Taxon-specific zeta -crystallin in Japanese tree frog (Hyla japonica) lens.

  The Journal of biological chemistry 20010727

• Evidence that NADP+ is the physiological cofactor of ADP-L-glycero-D-mannoheptose 6-epimerase.

  The Journal of biological chemistry 20010720

• Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors.

  Science (New York, N.Y.) 20010720

• Thiols prevent H2O2-mediated loss of sperm motility in cryopreserved bull semen.

  Theriogenology 20010715

• GroEL-assisted dehydrogenase folding mediated by coenzyme is ATP-independent.

  Biochemical and biophysical research communications 20010713

• Identification of the gene encoding NADH-rubredoxin oxidoreductase in Clostridium acetobutylicum.

  Biochemical and biophysical research communications 20010713

• Suppression of 12-O-tetradecanoylphorbol-13-acetate-induced epidermal hyperplasia and inflammation by the dehydroepiandrosterone analog 16alpha-fluoro-5-androsten-17-one and its reversal by NADPH liposomes.

  Cancer letters 20010710

• The in vitro evaluation of 'azo containing polysaccharide gels' for colon delivery.

  Journal of controlled release : official journal of the Controlled Release Society 20010710

• Exploring the active site of yeast xylose reductase by site-directed mutagenesis of sequence motifs characteristic of two dehydrogenase/reductase family types.

  FEBS letters 20010706

• Glucose uptake and metabolism by cultured human skeletal muscle cells: rate-limiting steps.

  American journal of physiology. Endocrinology and metabolism 20010701

• Rat liver microsomal enzyme catalyzed oxidation of 4-phenyl-trans-1-(2-phenylcyclopropyl)-1,2,3,6-tetrahydropyridine.

  Bioorganic & medicinal chemistry 20010701

• NAD(P)H, a directly operating antioxidant?

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010701

• Monitoring NAD(P)H autofluorescence to assess mitochondrial metabolic functions in rat hippocampal-entorhinal cortex slices.

  Brain research. Brain research protocols 20010701

• Cytochemically detectable glucose-6-phosphate dehydrogenase is present in human fetal membrane chorion laeve trophoblasts.

  Placenta 20010701

• Changes of in vivo fluxes through central metabolic pathways during the production of nystatin by Streptomyces noursei in batch culture.

  Applied microbiology and biotechnology 20010701

• Activity of key enzymes in microsomal and mitochondrial membranes depends on the redox reactions involving lipid radicals.

  Membrane & cell biology 20010701

• [Dynamic variance of intracellular metabolic energies under rhythmical control for dissolved oxygen in PHB mixed cultivation].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20010701

• Modulation of mitochondrial function by hydrogen peroxide.

  The Journal of biological chemistry 20010629

• Chimeras of nitric-oxide synthase types I and III establish fundamental correlates between heme reduction, heme-NO complex formation, and catalytic activity.

  The Journal of biological chemistry 20010629

• Calmodulin activates intersubunit electron transfer in the neuronal nitric-oxide synthase dimer.

  The Journal of biological chemistry 20010629

• Nitric oxide and the control of firefly flashing.

  Science (New York, N.Y.) 20010629

• NAADP receptors are present and functional in the heart.

  Current biology : CB 20010626

• In vivo role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in the regulation of intracellular redox state and accumulation of abdominal adipose tissue.

  The Journal of biological chemistry 20010622

• Structural assembly of the active site in an aldo-keto reductase by NADPH cofactor.

  Journal of molecular biology 20010622

• Spectral studies of tert-butyl isothiocyanate-inactivated P450 2E1.

  Biochemistry 20010619

• Erythromycin biosynthesis. The 4-pro-S hydride of NADPH is utilized for ketoreduction by both module 5 and module 6 of the 6-deoxyerythronolide B synthase.

  Bioorganic & medicinal chemistry letters 20010618

• Interaction of 11-cis-retinol dehydrogenase with the chromophore of retinal g protein-coupled receptor opsin.

  The Journal of biological chemistry 20010615

• Relationship between posttranslational modification of transaldolase and catalase deficiency in UV-sensitive repair-deficient xeroderma pigmentosum fibroblasts and SV40-transformed human cells.

  Free radical biology & medicine 20010615

• Expression, purification, and physical properties of recombinant flavocytochrome fusion proteins containing rat cytochrome b(5) linked to NADPH-cytochrome P450 reductase by different membrane-binding segments.

  Archives of biochemistry and biophysics 20010615

• NADPH-dependent glutathione peroxidase-like proteins (Gpx-1, Gpx-2) reduce unsaturated fatty acid hydroperoxides in Synechocystis PCC 6803.

  FEBS letters 20010615

• Mechanism of NAD(P)H:quinone reductase: Ab initio studies of reduced flavin.

  Proteins 20010601

• Effects of a Brussels sprouts extract on oxidative DNA damage and metabolising enzymes in rat liver.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010601

• Threonine synthesis from aspartate in Escherichia coli cell-free extracts: pathway dynamics.

  The Biochemical journal 20010601

• Pteridine reductase mechanism correlates pterin metabolism with drug resistance in trypanosomatid parasites.

  Nature structural biology 20010601

• Hexokinase isozyme distribution in human skeletal muscle.

  Diabetes 20010601

• NAADP induces Ca2+ oscillations via a two-pool mechanism by priming IP3- and cADPR-sensitive Ca2+ stores.

  The EMBO journal 20010601

• Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.

  Bioscience, biotechnology, and biochemistry 20010601

• Substrate selectivity of Gluconobacter oxydans for production of 2,5-diketo-D-gluconic acid and synthesis of 2-keto-L-gulonic acid in a multienzyme system.

  Applied biochemistry and biotechnology 20010601

• Sequence-specific DNA damage induced by carcinogenic danthron and anthraquinone in the presence of Cu(II), cytochrome P450 reductase and NADPH.

  Free radical research 20010601

• Purification and characterization of a novel phosphorus-oxidizing enzyme from Pseudomonas stutzeri WM88.

  The Journal of biological chemistry 20010518

• Human oestrogenic 17beta-hydroxysteroid dehydrogenase specificity: enzyme regulation through an NADPH-dependent substrate inhibition towards the highly specific oestrone reduction.

  The Biochemical journal 20010515

• Regulation of glutamate dehydrogenase by reversible ADP-ribosylation in mitochondria.

  The EMBO journal 20010515

• NADH oxidase activity of mitochondrial apoptosis-inducing factor.

  The Journal of biological chemistry 20010511

• Mycobacterium tuberculosis mycothione reductase: pH dependence of the kinetic parameters and kinetic isotope effects.

  Biochemistry 20010501

• Pyruvate : NADP+ oxidoreductase from the mitochondrion of Euglena gracilis and from the apicomplexan Cryptosporidium parvum: a biochemical relic linking pyruvate metabolism in mitochondriate and amitochondriate protists.

  Molecular biology and evolution 20010501

• NADP+ and NAD+ binding to the dual coenzyme specific enzyme Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase: different interdomain hinge angles are seen in different binary and ternary complexes.

  Acta crystallographica. Section D, Biological crystallography 20010501

• 4-Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB. A novel flavoprotein catalyzing Baeyer-Villiger oxidation of aromatic compounds.

  European journal of biochemistry 20010501

• Voltammetric biosensors for the determination of formate and glucose-6-phosphate based on the measurement of dehydrogenase-generated NADH and NADPH.

  Biosensors & bioelectronics 20010501

• Control of electron transfer in neuronal NO synthase.

  Biochemical Society transactions 20010501

• Purification and structure of the major product obtained by reaction of NADPH and NMNH with the myeloperoxidase/hydrogen peroxide/chloride system.

  European journal of biochemistry 20010501

• Protein engineering of Bacillus megaterium CYP102. The oxidation of polycyclic aromatic hydrocarbons.

  European journal of biochemistry 20010501

• [Genetic variation of NADPH/NADH oxidase and susceptibility to diffuse panbronchiolitis (DPB) and chronic obstructive pulmonary disease (COPD)].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20010501

• Important role of tetrahydrobiopterin in no complex formation and interdomain electron transfer in neuronal nitric-oxide synthase.

  Biochemical and biophysical research communications 20010420

• Metabolite and enzyme profiles of glycogen metabolism in Methanococcoides methylutens.

  FEMS microbiology letters 20010420

• Determination of the stereochemistry of hydride transfer from NADPH to FAD catalyzed by VlmR, a flavin reductase from the valanimycin biosynthetic pathway.

  Organic letters 20010419

• Reaction of neuronal nitric-oxide synthase with 2,6-dichloroindolphenol and cytochrome c3+: influence of the electron acceptor and binding of Ca2+-activated calmodulin on the kinetic mechanism.

  Biochemistry 20010417

• Characterization of mutants of beta histidine91, beta aspartate213, and beta asparagine222, possible components of the energy transduction pathway of the proton-translocating pyridine nucleotide transhydrogenase of Escherichia coli.

  Archives of biochemistry and biophysics 20010415

• Binding of pyridine nucleotide coenzymes to the beta-subunit of the voltage-sensitive K+ channel.

  The Journal of biological chemistry 20010413

• Crystal structure of the MJ0490 gene product of the hyperthermophilic archaebacterium Methanococcus jannaschii, a novel member of the lactate/malate family of dehydrogenases.

  Journal of molecular biology 20010413

• In vitro metabolism of gestodene in target organs: formation of A-ring reduced derivatives with oestrogenic activity.

  European journal of pharmacology 20010413

• Structural basis for a change in substrate specificity: crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP.

  Biochemistry 20010410

• Prolonged inactivation of nicotinic acid adenine dinucleotide phosphate-induced Ca2+ release mediates a spatiotemporal Ca2+ memory.

  The Journal of biological chemistry 20010406

• Re-face stereospecificity of NADP dependent methylenetetrahydromethanopterin dehydrogenase from Methylobacterium extorquens AM1 as determined by NMR spectroscopy.

  FEBS letters 20010406

• Crystal structures of a novel ferric reductase from the hyperthermophilic archaeon Archaeoglobus fulgidus and its complex with NADP+.

  Structure (London, England : 1993) 20010404

• Plasma membrane electron transport coupled to Na(+) extrusion in the halotolerant alga Dunaliella.

  Biochimica et biophysica acta 20010402

• K+ channels and the microglial respiratory burst.

  American journal of physiology. Cell physiology 20010401

• Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin.

  Drug metabolism and disposition: the biological fate of chemicals 20010401

• Decreases in phenytoin hydroxylation activities catalyzed by liver microsomal cytochrome P450 enzymes in phenytoin-treated rats.

  Drug metabolism and disposition: the biological fate of chemicals 20010401

• Blood glutathione redox status in gestational hypertension.

  Free radical biology & medicine 20010401

• Nitroxyl oxidizes NADPH in a superoxide dismutase inhibitable manner.

  Free radical biology & medicine 20010401

• Characterization of the flavoprotein domain of gp91phox which has NADPH diaphorase activity.

  Journal of biochemistry 20010401

• Oxidative damage and direct adducts in calf thymus DNA induced by the pentachlorophenol metabolites, tetrachlorohydroquinone and tetrachloro-1,4-benzoquinone.

  Carcinogenesis 20010401

• Peroxisomes as a source of reactive oxygen species and nitric oxide signal molecules in plant cells.

  Trends in plant science 20010401

• Modulation of cerebellar and hepatic nitric oxide synthase by exogenous arginine and endotoxin.

  Nitric oxide : biology and chemistry 20010401

• Ca2+ signalling and changes of mitochondrial function during low-Mg2+-induced epileptiform activity in organotypic hippocampal slice cultures.

  The European journal of neuroscience 20010401

• Generation of reactive oxygen species by equine spermatozoa.

  American journal of veterinary research 20010401

• Toxoplasmosis in a group of glucose-6-phosphate dehydrogenase deficient patients.

  Saudi medical journal 20010401

• The NADH diphosphatase encoded by the Saccharomyces cerevisiae NPY1 nudix hydrolase gene is located in peroxisomes.

  Archives of biochemistry and biophysics 20010401

• Oxidative catabolism of alpha-tocopherol in rat liver microsomes.

  Lipids 20010401

• Wax ester biosynthesis in the liver of myctophid fishes.

  Lipids 20010401

• The role of serine-246 in cytochrome P450eryF-catalyzed hydroxylation of 6-deoxyerythronolide B.

  Bioscience, biotechnology, and biochemistry 20010401

• Elevation of blood NAD level after moderate exercise in young women and mice.

  Journal of nutritional science and vitaminology 20010401

• Cost-effective whole-cell assay for laboratory evolution of hydroxylases in Escherichia coli.

  Journal of biomolecular screening 20010401

• Activation of class III ribonucleotide reductase by thioredoxin.

  The Journal of biological chemistry 20010330

• Activation of class III ribonucleotide reductase by flavodoxin: a protein radical-driven electron transfer to the iron-sulfur center.

  Biochemistry 20010327

• Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation.

  Journal of molecular biology 20010323

• Electron spin resonance characterization of the NAD(P)H oxidase in vascular smooth muscle cells.

  Free radical biology & medicine 20010315

• Characterization of metabolic activation of pentachlorophenol to quinones and semiquinones in rodent liver.

  Chemico-biological interactions 20010314

• Dynamic responses of Pseudomonas fluorescens DF57 to nitrogen or carbon source addition.

  Journal of biotechnology 20010309

• Hydrophobicity of the NADPH binding domain of camel lens zeta-crystallin.

  Biochimica et biophysica acta 20010309

• Glucose deprivation and chemical hypoxia: neuroprotection by P2 receptor antagonists.

  Neurochemistry international 20010301

• Reactive oxygen species from NAD(P)H:quinone oxidoreductase constitutively activate NF-kappaB in malignant melanoma cells.

  American journal of physiology. Cell physiology 20010301

• Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20010301

• Enhanced level of n-3 fatty acid in membrane phospholipids induces lipid peroxidation in rats fed dietary docosahexaenoic acid oil.

  Atherosclerosis 20010301

• Lysophosphatidylcholine increases the secretion of matrix metalloproteinase 2 through the activation of NADH/NADPH oxidase in cultured aortic endothelial cells.

  Atherosclerosis 20010301

• Crystallization and preliminary X-ray analysis of a NADPH 2-ketopropyl-coenzyme M oxidoreductase/carboxylase.

  Acta crystallographica. Section D, Biological crystallography 20010301

• Molecular basis for Rac2 regulation of phagocyte NADPH oxidase.

  Nature immunology 20010301

• Structure of human biliverdin IXbeta reductase, an early fetal bilirubin IXbeta producing enzyme.

  Nature structural biology 20010301

• Crystal structure of rat biliverdin reductase.

  Nature structural biology 20010301

• Inhibition of aldosterone production in rat adrenal mitochondria by 18-ethynyl-11-deoxycorticosterone: a simple model for kinetic interpretation of mechanism-based inhibitors.

  Journal of biochemistry 20010301

• A critical investigation of NADPH oxidase activity in human spermatozoa.

  Molecular human reproduction 20010301

• A change in ionization of the NADP(H)-binding component (dIII) of proton-translocating transhydrogenase regulates both hydride transfer and nucleotide release.

  European journal of biochemistry 20010301

• Reduction of ubiquinone by lipoamide dehydrogenase. An antioxidant regenerating pathway.

  European journal of biochemistry 20010301

• Expression of recombinant zeta-crystallin in Escherichia coli with the help of GroEL/ES and its purification.

  Protein expression and purification 20010301

• NAD(P)H:menadione oxidoreductase of the amitochondriate eukaryote Giardia lamblia: a simpler homologue of the vertebrate enzyme.

  Microbiology (Reading, England) 20010301

• A comparative study of the ability of ferric nitrilotriacetate [correction of nitriloacetate] and other iron chelators to assist membrane lipid peroxidation by superoxide radicals.

  Chemistry and physics of lipids 20010301

• Purification and characterization of the fatty acid synthase from Bugula neritina.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010301

• Relationship between effects of phenolic compounds on the generation of free radicals from lactoperoxidase-catalyzed oxidation of NAD(P)H or GSH and their DPPH scavenging ability.

  Chemical & pharmaceutical bulletin 20010301

• Kinetic properties of human placental glucose-6-phosphate dehydrogenase.

  The international journal of biochemistry & cell biology 20010301

• Time-dependent XAS studies of trapped enzyme-substrate complexes of alcohol dehydrogenase from Thermoanaerobacter brockii.

  Journal of synchrotron radiation 20010301

• Purification and characterization of aminopropionaldehyde dehydrogenase from Arthrobacter sp. TMP-1.

  FEMS microbiology letters 20010220

• Differences in Fe(III) reduction in the hyperthermophilic archaeon, Pyrobaculum islandicum, versus mesophilic Fe(III)-reducing bacteria.

  FEMS microbiology letters 20010220

• Stopped-flow kinetic studies of flavin reduction in human cytochrome P450 reductase and its component domains.

  Biochemistry 20010220

• NAD+ inhibits the self-splicing of the group I intron.

  Biochemical and biophysical research communications 20010216

• Crystal structure of the NADP(H)-dependent ketose reductase from Bemisia argentifolii at 2.3 A resolution.

  Journal of molecular biology 20010216

• Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide.

  Biochimica et biophysica acta 20010216

• Differential transfers of reduced flavin cofactor and product by bacterial flavin reductase to luciferase.

  Biochemistry 20010213

• Critical role of the residue size at position 87 in H2O2- dependent substrate hydroxylation activity and H2O2 inactivation of cytochrome P450BM-3.

  Biochemical and biophysical research communications 20010209

• The crystal structure of an asymmetric complex of the two nucleotide binding components of proton-translocating transhydrogenase.

  Structure (London, England : 1993) 20010207

• Kinetic and mechanistic properties of biotin sulfoxide reductase.

  Biochemistry 20010206

• Vascular NAD(P)H oxidase is distinct from the phagocytic enzyme and modulates vascular reactivity control.

  American journal of physiology. Heart and circulatory physiology 20010201

• Metabolism of a disulfiram metabolite, S-methyl N,N-diethyldithiocarbamate, by flavin monooxygenase in human renal microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20010201

• Metabolism of amiodarone (part I): identification of a new hydroxylated metabolite of amiodarone.

  Drug metabolism and disposition: the biological fate of chemicals 20010201

• Application of rat hepatocyte culture to predict in vivo metabolic auto-induction: studies with DFP, a cyclooxygenase-2 inhibitor.

  Drug metabolism and disposition: the biological fate of chemicals 20010201

• Intrinsic neurons in the duck choroid are contacted by CGRP-immunoreactive nerve fibres: evidence for a local pre-central reflex arc in the eye.

  Experimental eye research 20010201

• The time-course of acid excretion, levels of fluorescence dependent on cellular nicotinamide adenine nucleotide and glycolytic intermediates of Streptococcus mutans cells exposed and not exposed to air in the presence of glucose and sorbitol.

  Oral microbiology and immunology 20010201

• Nicotinic acid-adenine dinucleotide phosphate (NAADP) elicits specific microsomal Ca2+ release from mammalian cells.

  The Biochemical journal 20010201

• Role of Ins(1,4,5)P3, cADP-ribose and nicotinic acid-adenine dinucleotide phosphate in Ca2+ signalling in mouse submandibular acinar cells.

  The Biochemical journal 20010201

• Predominant 4-hydroxylation of estradiol by constitutive cytochrome P450s in the female ACI rat liver.

  Carcinogenesis 20010201

• Characterization of the lys2 gene of Acremonium chrysogenum encoding a functional alpha-aminoadipate activating and reducing enzyme.

  Molecular & general genetics : MGG 20010201

• Oxidations of N(omega)-hydroxyarginine analogues and various N-hydroxyguanidines by NO synthase II: key role of tetrahydrobiopterin in the reaction mechanism and substrate selectivity.

  Chemical research in toxicology 20010201

• Effect of nicotinic acid adenine dinucleotide phosphate on ryanodine calcium release channel in heart.

  Pflugers Archiv : European journal of physiology 20010201

• Cytoplasmic Ca2+ at low submicromolar concentration stimulates mitochondrial metabolism in rat luteal cells.

  Pflugers Archiv : European journal of physiology 20010201

• Contrasting effects of acute and chronic dietary exposure to 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ) on xenobiotic metabolising enzymes in the male Fischer 344 rat: implications for chemoprevention studies.

  European journal of nutrition 20010201

• Differences in nucleotide specificity and catalytic mechanism between Vibrio harveyi aldehyde dehydrogenase and other members of the aldehyde dehydrogenase superfamily.

  Chemico-biological interactions 20010130

• Coenzyme specificity in aldehyde dehydrogenase.

  Chemico-biological interactions 20010130

• Making an Oriental equivalent of the yeast cytosolic aldehyde dehydrogenase as well as making one with positive cooperativity in coenzyme binding by mutations of glutamate 492 and arginine 480.

  Chemico-biological interactions 20010130

• The crystal structure of the GCY1 protein from S. cerevisiae suggests a divergent aldo-keto reductase catalytic mechanism.

  Chemico-biological interactions 20010130

• Structural and functional properties of aldose xylose reductase from the D-xylose-metabolizing yeast Candida tenuis.

  Chemico-biological interactions 20010130

• Molecular mechanisms of estrogen recognition and 17-keto reduction by human 17beta-hydroxysteroid dehydrogenase 1.

  Chemico-biological interactions 20010130

• The crystal structure of an aldehyde reductase Y50F mutant-NADP complex and its implications for substrate binding.

  Chemico-biological interactions 20010130

• Identity of dimeric dihydrodiol dehydrogenase as NADP(+)-dependent D-xylose dehydrogenase in pig liver.

  Chemico-biological interactions 20010130

• Coenzyme specificity of human monomeric carbonyl reductase: contribution of Lys-15, Ala-37 and Arg-38.

  Chemico-biological interactions 20010130

• Binding of pyridine coenzymes to the beta-subunit of the voltage sensitive potassium channels.

  Chemico-biological interactions 20010130

• Structure and site-directed mutagenesis of a flavoprotein from Escherichia coli that reduces nitrocompounds: alteration of pyridine nucleotide binding by a single amino acid substitution.

  The Journal of biological chemistry 20010126

• The reactive oxygen species--and Michael acceptor-inducible human aldo-keto reductase AKR1C1 reduces the alpha,beta-unsaturated aldehyde 4-hydroxy-2-nonenal to 1,4-dihydroxy-2-nonene.

  The Journal of biological chemistry 20010126

• Substitution of the thioredoxin system for glutathione reductase in Drosophila melanogaster.

  Science (New York, N.Y.) 20010126

• An old but simple and efficient method to elucidate the oxidation mechanism of NAD(P)H model 1-Aryl-1,4-dihydronicotinamides by cations 2-methyl-5-nitroisoquinolium, tropylium, and xanthylium in aqueous solution.

  The Journal of organic chemistry 20010126

• Inhibitors of type II 17beta-hydroxysteroid dehydrogenase.

  Molecular and cellular endocrinology 20010122

• Expression of the 17beta-hydroxysteroid dehydrogenase type 5 mRNA in the human brain.

  Molecular and cellular endocrinology 20010122

• Evolution of 17beta-hydroxysteroid dehydrogenases and their role in androgen, estrogen and retinoid action.

  Molecular and cellular endocrinology 20010122

• Electron pathways involved in H(2)-metabolism in the green alga Scenedesmus obliquus.

  Biochimica et biophysica acta 20010119

• Purification of ferredoxins and their reaction with purified reaction center complex from the green sulfur bacterium Chlorobium tepidum.

  Biochimica et biophysica acta 20010119

• Expression of a cytoplasmic transhydrogenase in Saccharomyces cerevisiae results in formation of 2-oxoglutarate due to depletion of the NADPH pool.

  Yeast (Chichester, England) 20010115

• Glutamine metabolism to glucosamine is necessary for glutamine inhibition of endothelial nitric oxide synthesis.

  The Biochemical journal 20010115

• Oxidation of pyridine nucleotides during Fas- and ceramide-induced apoptosis in Jurkat cells: correlation with changes in mitochondria, glutathione depletion, intracellular acidification and caspase 3 activation.

  The Biochemical journal 20010115

• Rac2 is an essential regulator of neutrophil nicotinamide adenine dinucleotide phosphate oxidase activation in response to specific signaling pathways.

  Journal of immunology (Baltimore, Md. : 1950) 20010115

• Thioredoxin converts the Syrian hamster (29-231) recombinant prion protein to an insoluble form.

  Free radical biology & medicine 20010115

• A kinetic simulation model that describes catalysis and regulation in nitric-oxide synthase.

  The Journal of biological chemistry 20010112

• High-affinity binding of NADPH to camel lens zeta-crystallin.

  Biochimica et biophysica acta 20010112

• Structures of trihydroxynaphthalene reductase-fungicide complexes: implications for structure-based design and catalysis.

  Structure (London, England : 1993) 20010110

• Mutations in the Kv beta 2 binding site for NADPH and their effects on Kv1.4.

  The Journal of biological chemistry 20010105

• Glutathione attenuates coronary constriction to acetylcholine in patients with coronary spastic angina.

  American journal of physiology. Heart and circulatory physiology 20010101

• Nicotinic acid adenine dinucleotide phosphate: a new Ca2+ releasing agent in kidney.

  Journal of the American Society of Nephrology : JASN 20010101

• Overexpression of wild type and SeCys/Cys mutant of human thioredoxin reductase in E. coli: the role of selenocysteine in the catalytic activity.

  Free radical biology & medicine 20010101

• Inhibition of protein synthesis sequentially impairs distinct steps of stimulus-secretion coupling in pancreatic beta cells.

  Endocrinology 20010101

• The biosynthesis of nicotinamide adenine dinucleotides in bacteria.

  Vitamins and hormones 20010101

• Apparent absence of a redox requirement for blue light activation of pump current in broad bean guard cells.

  Plant physiology 20010101

• Fatty acid chain elongation synthesis in eel (Anguilla anguilla) liver mitochondria.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010101

• Regulation of cyclosporin A sensitive mitochondrial permeability transition by the redox state of pyridine nucleotides.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010101

• Effects of nicotinamide coenzymes on the stability of enzyme activities and proteins in niacin-deficient quail tissues against trypsin treatment.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010101

• Mercury inhibition of neutrophil activity: evidence of aberrant cellular signalling and incoherent cellular metabolism.

  Scandinavian journal of immunology 20010101

• Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and thiazolidinedione ring scission.

  Chemical research in toxicology 20010101

• Lipids and NADPH-dependent superoxide production in plasma membrane vesicles from roots of wheat grown under copper deficiency or excess.

  Journal of experimental botany 20010101

• Specific Ca2+ signaling evoked by cholecystokinin and acetylcholine: the roles of NAADP, cADPR, and IP3.

  Annual review of physiology 20010101

• Evaluation of hexose monophosphate shunt activity in isolated murine lens by monitoring the potential of the ferricyanide--ferrocyanide system.

  Biochemistry. Biokhimiia 20010101

• Indole-3-propionic acid, a melatonin-related molecule, protects hepatic microsomal membranes from iron-induced oxidative damage: relevance to cancer reduction.

  Journal of cellular biochemistry 20010101

• Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase from Thermoproteus tenax.

  Methods in enzymology 20010101

• Valine 77 of heterocystous ferredoxin FdxH2 in Anabaena variabilis strain ATCC 29413 is critical for its oxygen sensitivity.

  Molecular and cellular biochemistry 20010101

• Non-enzymatic reduction of aliphatic tertiary amine N-oxides mediated by the haem moiety of cytochrome P450.

  Xenobiotica; the fate of foreign compounds in biological systems 20010101

• Polymer modified electrodes for the reversible oxidation-reduction of NAD+/NADH for use within amperometric biosensors.

  Biomedical sciences instrumentation 20010101

• NADPH and NADH serve as electron donor for the superoxide-generating enzyme in tilapia (Oreochromis niloticus) neutrophils.

  Developmental and comparative immunology 20010101

• Influence of metal ions on flavonoid protection against asbestos-induced cell injury.

  Archives of biochemistry and biophysics 20010101

• Conformational change of Arabidopsis thaliana thioredoxin reductase after binding of pyridine nucleotide and thioredoxin.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101

• K(Ca) channel-opening activity of Ginkgo Biloba extracts and ginsenosides in cultured endothelial cells.

  Clinical and experimental pharmacology & physiology 20010101

• Ferredoxin:NADP oxidoreductase from Pyrococcus furiosus.

  Methods in enzymology 20010101

• Glutamate synthesis via photoreduction of NADP+ by photostable chlorophyllide coupled with polyethylene-glycol.

  Biotechnology and bioengineering 20010101

• Frog oocytes: a living test tube for studies on metabolic regulation.

  IUBMB life 20010101

• The origin of photo-oxidative stress in the aging eye.

  Progress in brain research 20010101

• Effect of chronic ozone fumigation on the photosynthetic process of poplar clones showing different sensitivity.

  Environmental pollution (Barking, Essex : 1987) 20010101

• A redox-regulated tyrosine phosphorylation cascade in rat spermatozoa.

  Journal of andrology 20010101

• Menadione-catalyzed O2- production by Escherichia coli cells: application of rapid chemiluminescent assay to antimicrobial susceptibility testing.

  Microbiology and immunology 20010101

• Interactions of melatonin with the liver microsomal cytochrome P450 system of rats and humans in vitro and effects on the P450 system and the antioxidative status in rat liver after acute treatment.

  European journal of drug metabolism and pharmacokinetics 20010101

• Glutathione peroxidase-1 gene knockout on body antioxidant defense in mice.

  BioFactors (Oxford, England) 20010101

• Pharmacokinetics of the novel, high-affinity and selective dopamine D3 receptor antagonist SB-277011 in rat, dog and monkey: in vitro/in vivo correlation and the role of aldehyde oxidase.

  Xenobiotica; the fate of foreign compounds in biological systems 20010101

• Effect of adamantanone derivative possessing anti-HIV properties on the redox processes in the cytochrome P-450 system.

  Doklady. Biochemistry and biophysics 20010101

• Biochemical studies of patients with Cuban epidemic neuropathy.

  Ophthalmic research 20010101

• Role of extracellular peroxidase in the superoxide production by wheat root cells.

  Protoplasma 20010101

• The perfused guinea-pig lung revisited: a study of EDRF-no system.

  Research communications in molecular pathology and pharmacology 20010101

• Use of isotopes and LC-MS-ESI-TOF for mechanistic studies of tienilic acid metabolic activation.

  Advances in experimental medicine and biology 20010101

• Inhibition by ticlopidine and its derivatives of human liver cytochrome p450. Mechanism-based inactivation of CYP 2C19 by ticlopidine.

  Advances in experimental medicine and biology 20010101

• Inhibitory effects of roquefortine on hepatic cytochromes P450.

  Advances in experimental medicine and biology 20010101

• Effect of the microsomal system on quinone redox cycling, oxygen activation, and lipid peroxidation.

  Advances in experimental medicine and biology 20010101

• Construction of Salmonella typhimurium YG7108 strains, each coexpressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase.

  Environmental and molecular mutagenesis 20010101

• Effect of phenobarbital and spironolactone treatment on the oxidative metabolism of antipyrine by rat liver microsomes.

  Polish journal of pharmacology 20010101

• Menadione-catalyzed luminol chemiluminescent assay for the viability of Escherichia coli ATCC 25922.

  Microbiology and immunology 20010101

• Sequencing, expression, and characterization of cDNA expressed flavin-containing monooxygenase 2 from mouse.

  Journal of biochemical and molecular toxicology 20010101

• NADPH-induced oxidative damage of rat liver microsomes: protective role of chlorpromazine and trifluoperazine.

  Polish journal of pharmacology 20010101

• Converging catabolism of 2,4,6-trinitrophenol (picric acid) and 2,4-dinitrophenol by Nocardioides simplex FJ2-1A.

  Biodegradation 20010101

• Computer modeling studies of the structural role of NADPH binding to active site mutants of human dihydrofolate reductase in complex with piritrexim.

  Acta biochimica Polonica 20010101

• The role of 5alpha-reduction in steroid hormone physiology.

  Reproduction, fertility, and development 20010101

• Ontogenesis of oxidative reaction of 17beta-hydroxysteroid dehydrogenase and 11beta-hydroxysteroid dehydrogenase in rat Leydig cells, a histochemical study.

  The Histochemical journal 20010101

• [Diabetic neuropathies. Metabolism of sorbitol in sciatic nerve tissue in streptozotocin diabetes].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20010101

• [Effect of L-arginine and N(omega)-nitro-L-arginine on oxidative phosphorylation and lipid peroxidation in rats with various tolerance to hypoxia under stressful conditions].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20010101

• Changes in enzymatic activities involved in glucose metabolism by acyl-CoAs in Trypanosoma cruzi.

  Canadian journal of microbiology 20010101

• The structure of the catalytic portion of human HMG-CoA reductase.

  Biochimica et biophysica acta 20001215

• Conversion of 4-hydroxyacetophenone into 4-phenyl acetate by a flavin adenine dinucleotide-containing Baeyer-Villiger-type monooxygenase.

  Journal of bacteriology 20001201

• Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants.

  Biochemistry 20000919

• NADPH- and hydroperoxide-supported 17beta-estradiol hydroxylation catalyzed by a variant form (432L, 453S) of human cytochrome P450 1B1.

  The Journal of steroid biochemistry and molecular biology 20000901

• Identification of enzymes responsible for rifalazil metabolism in human liver microsomes.

  Xenobiotica; the fate of foreign compounds in biological systems 20000601

• Reduction of hydroxamic acids to the corresponding amides catalyzed by rabbit blood.

  Xenobiotica; the fate of foreign compounds in biological systems 20000501

• Structural studies on bioactive compounds. 30. Crystal structure and molecular modeling studies on the Pneumocystis carinii dihydrofolate reductase cofactor complex with TAB, a highly selective antifolate.

  Biochemistry 20000404

• New functions of a long-known molecule. Emerging roles of NAD in cellular signaling.

  European journal of biochemistry 20000301

• Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase.

  Journal of lipid research 20000201

• Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs.

  Journal of molecular biology 20000114

• Stimulation of tolbutamide hydroxylation by acetone and acetonitrile in human liver microsomes and in a cytochrome P-450 2C9-reconstituted system.

  Drug metabolism and disposition: the biological fate of chemicals 20000101

• Role of molecular oxygen in the generation of hydroxyl and superoxide anion radicals during enzymatic Cr(VI) reduction and its implication to Cr(VI)-induced carcinogenesis.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20000101

• A role for coenzyme M (2-mercaptoethanesulfonic acid) in a bacterial pathway of aliphatic epoxide carboxylation.

  Proceedings of the National Academy of Sciences of the United States of America 19990720

• Identification, characterization, and partial purification of 4 alpha-carboxysterol-C3-dehydrogenase/ C4-decarboxylase from Zea mays.

  Archives of biochemistry and biophysics 19990615

• Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+.

  Proceedings of the National Academy of Sciences of the United States of America 19990202

• Biological inactivation of 5-oxo-6,8,11,14-eicosatetraenoic acid by human platelets.

  Blood 19990201

• Structure-based design and synthesis of lipophilic 2,4-diamino-6-substituted quinazolines and their evaluation as inhibitors of dihydrofolate reductases and potential antitumor agents.

  Journal of medicinal chemistry 19980827

• Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds.

  The Journal of biological chemistry 19980807

• 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces hepatic cytochrome P450-dependent arachidonic acid epoxygenation in diverse avian orders: regioisomer selectivity and immunochemical comparison of the TCDD-induced P450s to CYP1A4 and 1A5.

  Toxicology and applied pharmacology 19980501

• Mechanistic studies of the biosynthesis of paratose: purification and characterization of CDP-paratose synthase.

  Biochemistry 19980407

• Proliferation of airway epithelium after ozone exposure: effect of apocynin and dexamethasone.

  American journal of respiratory and critical care medicine 19980301

• Biotransformation patterns of 2,4,6-trinitrotoluene by aerobic bacteria.

  Current microbiology 19980101

• Hepatic hyperplasia and cancer in rats: metabolic alterations associated with cell growth.

  Gastroenterology 19970701

• Pro- and anti-oxidant activities of the mitochondrial respiratory chain: factors influencing NAD(P)H-induced lipid peroxidation.

  Biochimica et biophysica acta 19970116

• Induction of p21 mediated by reactive oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells.

  The Journal of biological chemistry 19961213

• Sequence and properties of pentaerythritol tetranitrate reductase from Enterobacter cloacae PB2.

  Journal of bacteriology 19961101

• Hydroxylation of ent-kaurenoic acid to steviol in Stevia rebaudiana Bertoni--purification and partial characterization of the enzyme.

  Archives of biochemistry and biophysics 19960815

• Inhibition kinetics of camel lens zeta-crystallin: multiple inhibition studies.

  Journal of enzyme inhibition 19960801

• NADPH-dependent reductive ortho dehalogenation of 2,4-dichlorobenzoic acid in Corynebacterium sepedonicum KZ-4 and Coryneform bacterium strainNTB-1 via 2,4-dichlorobenzoyl coenzyme A.

  Journal of bacteriology 19960501

• Reductive activation of 1,1-dichloro-1-fluoroethane (HCFC-141b) by phenobarbital- and pyridine-induced rat liver microsomal cytochrome P450.

  Xenobiotica; the fate of foreign compounds in biological systems 19960401

• Iron-stimulated ring-opening of benzene in a mouse liver microsomal system. Mechanistic studies and formation of a new metabolite.

  Biochemical pharmacology 19951109

• Purification and characterization of nitrobenzene nitroreductase from Pseudomonas pseudoalcaligenes JS45.

  Journal of bacteriology 19950701

• The role of iron chelators and oxygen in the reduced nicotinamide adenine dinucleotide phosphate-cytochrome P450 oxidoreductase-dependent chromium(VI) reduction.

  The Analyst 19950301

• Expression, purification, and characterization of the human squalene synthase: use of yeast and baculoviral systems.

  Archives of biochemistry and biophysics 19950201

• In vivo and in vitro sevoflurane-induced lipid peroxidation in guinea-pig liver microsomes.

  Pharmacology & toxicology 19941201

• Alterations of drug metabolizing and antioxidant enzyme activities during tamoxifen-induced hepatocarcinogenesis in the rat.

  Carcinogenesis 19940501

• Mechanism of inhibition of trypanothione reductase and glutathione reductase by trivalent organic arsenicals.

  European journal of biochemistry 19940401

• Liver NADPH-dependent oxidation of the 5-nitrofurans, FANFT and ANFT, by guinea pig and rat.

  Xenobiotica; the fate of foreign compounds in biological systems 19930201

• The crystal structure of the aldose reductase.NADPH binary complex.

  The Journal of biological chemistry 19921205

• NAD(P)H-dependent chromium (VI) reductase of Pseudomonas ambigua G-1: a Cr(V) intermediate is formed during the reduction of Cr(VI) to Cr(III).

  Journal of bacteriology 19920801

• Reduction of chromium(VI) to chromium(V) by rat liver cytosolic and microsomal fractions: is DT-diaphorase involved?

  Carcinogenesis 19920701

• Identification and characterization of the enzymatic activity of zeta-crystallin from guinea pig lens. A novel NADPH:quinone oxidoreductase.

  The Journal of biological chemistry 19920105

• Hydroxyl radical formation and lipid peroxidation enhancement by chromium. In vitro study.

  Biological trace element research 19920101

• Structure of the detoxification catalyst mercuric ion reductase from Bacillus sp. strain RC607.

  Nature 19910711

• Affinity purification and characterization of 2,4-dichlorophenol hydroxylase from Pseudomonas cepacia.

  Archives of biochemistry and biophysics 19910701

• The role of NADPH in the regulation of glucose-6-phosphate and 6-phosphogluconate dehydrogenases in rat adipose tissue.

  Molecular and cellular biochemistry 19910626

• Defenses against oxidation in human erythrocytes: role of glutathione reductase in the activation of glucose decarboxylation by hemolytic drugs.

  The Journal of laboratory and clinical medicine 19910401

• Metabolic activation of 1,2,4-trichlorobenzene and pentachlorobenzene by rat liver microsomes: a major role for quinone metabolites.

  Toxicology and applied pharmacology 19910401

• N-terminus determination: FAD and NADP binding domain mapping of hog liver flavin-containing monooxygenase by tandem mass spectrometry.

  Biochemical and biophysical research communications 19900731

• The biosynthesis of tetrahydrobiopterin in rat brain. Purification and characterization of 6-pyruvoyl tetrahydropterin (2'-oxo)reductase.

  The Journal of biological chemistry 19890515

• Purification and properties of phloroglucinol reductase from Eubacterium oxidoreducens G-41.

  The Journal of biological chemistry 19890315

• Reactions of adriamycin with microsomal iron and lipids.

  Free radical research communications 19890101

• [Synthesis and antimycobacterial action of lipophilic substituted 2,4-diamino-5-benzylpyrimidines].

  Arzneimittel-Forschung 19881201

• Inhibition of doxorubicin-initiated membrane damage by N-acetylcysteine: possible mediation by a thiol-dependent, cytosolic inhibitor of lipid peroxidation.

  Toxicology and applied pharmacology 19881101

• Cloning and expression of a cDNA for human thioredoxin.

  The Journal of biological chemistry 19881025

• The NADPH-linked acetoacetyl-CoA reductase from Zoogloea ramigera. Characterization and mechanistic studies of the cloned enzyme over-produced in Escherichia coli.

  European journal of biochemistry 19880516

• Effect of orally administered 9-oxononanoic acid on lipogenesis in rat liver.

  Biochimica et biophysica acta 19880204

• Conversion of leukotriene A4 to leukotriene B4: catalysis by human liver microsomes under anaerobic conditions.

  Archives of biochemistry and biophysics 19871201

• Activity of antifolates against Pneumocystis carinii dihydrofolate reductase and identification of a potent new agent.

  The Journal of experimental medicine 19870301

• Purification and properties of 4-aminobenzoate hydroxylase, a new monooxygenase from Agaricus bisporus.

  The Journal of biological chemistry 19861005

• Detoxifying activities in alveolar macrophages of rats treated with acetylcysteine, diethyl maleate and/or aroclor.

  Anticancer research 19860101

• Effects of oxidative stress caused by hyperoxia and diquat. A study in isolated hepatocytes.

  Free radical research communications 19860101

• Leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes. Suicidal inactivation by acetylenic fatty acids.

  The Journal of biological chemistry 19851025

• Activation of rat liver microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase by NADPH. Effects of dietary treatments.

  The Journal of biological chemistry 19851015

• Prominent role of DT-diaphorase as a cellular mechanism reducing chromium(VI) and reverting its mutagenicity.

  Cancer research 19850701

• Purification and properties of NADH/NADPH-dependent p-hydroxybenzoate hydroxylase from Corynebacterium cyclohexanicum.

  European journal of biochemistry 19850215

• The NADP+-binding site of ferredoxin-NADP+ reductase. Sequence of the peptide containing the essential lysine residue.

  European journal of biochemistry 19850115

• Squalene synthetase.

  Methods in enzymology 19850101

• Protective action of 2(3)-tert-butyl-4-hydroxyanisole (BHA) on acetaminophen-induced liver necrosis in male A/J mice.

  Research communications in chemical pathology and pharmacology 19841201

• Cytochrome P-450 system dependent depression of delta-aminolevulinic acid dehydratase activity by bromobenzene in rats.

  Toxicology 19840701

• Patulin biosynthesis: enzymatic and nonenzymatic transformations of the mycotoxin (E)-ascladiol.

  Applied and environmental microbiology 19830601

• Lipid peroxidation: a possible mechanism of cephaloridine-induced nephrotoxicity.

  Toxicology and applied pharmacology 19830101

• Activity of sulfa drugs and dihydrofolate reductase inhibitors against Candida albicans.

  Experientia 19820415

• The purification and properties of 2,4-dichlorophenol hydroxylase from a strain of Acinetobacter species.

  European journal of biochemistry 19820401

• Possible involvement of the enhanced tryptophan pyrrolase activity in the corticosterone- and starvation-induced increases in concentrations of nicotinamide-adenine dinucleotides (phosphates) in rat liver.

  The Biochemical journal 19810415

• Equilibrium substrate binding studies of the malic enzyme of pigeon liver. Equivalence of nucleotide sites and anticooperativity associated with the binding of L-malate to the enzyme-manganese(II)-reduced nicotinamide adenine dinucleotide phosphate ternary complex.

  Biochemistry 19800304

• Squalene synthetase.

  Molecular and cellular biochemistry 19791015

• The catabolism of L-tyrosine by an Arthrobacter sp.

  Canadian journal of microbiology 19770901

• The purification and properties of 4-hydroxyisophthalate hydroxylase from Pseudomonas putida NCIB 9866.

  European journal of biochemistry 19770601

• Identification of a functional arginine residue involved in coenzyme binding by the NADP-specific glutamate dehydrogenase of Neurospora.

  The Journal of biological chemistry 19760925

• Bacterial metabolism of resorcinylic compounds: purification and properties of orcinol hydroxylase and resorcinol hydroxylase from Pseudomonas putida ORC.

  European journal of biochemistry 19760102

• Purification and properties of polyol dehydrogenase from Cephalosporium chrysogenus.

  Journal of bacteriology 19760101

• The metabolism of cyclohexanol by Acinetobacter NCIB 9871.

  European journal of biochemistry 19751201

• Biochemical aspects of the visual process. XXXI. Chemical modification studies on rod outer segment retinol dehydrogenase.

  Experimental eye research 19751201

• Fluorescence of oxidized flavoproteins from perifused isolated pancreatic islets.

  Diabetologia 19751201

• Nucleosides and nucleotides of the cold acid-soluble portion of the blood of steers.

  Journal of animal science 19751201

• Further studies on lipid-peroxide formation in isolated hepatocytes.

  European journal of biochemistry 19751115

• D-glucose-6-phosphate dehydrogenase (Entner-Doudoroff enzyme) from Pseudomonas fluorescens. Purification, properties and regulation.

  European journal of biochemistry 19751115

• [Adenine and pyridine nucleotides in forms of Verticillium dahliae Kleb. differing in pathogenicity].

  Doklady Akademii nauk SSSR 19751021

• Two enzymes in Streptomyces griseus forb the synthesis of dTDP-L-dihydrostreptose from dTDP-6-deoxy-D-xylo-4-hexosulose.

  Biochemical and biophysical research communications 19750102

• Metabolic function and properties of 4-hydroxyphenylacetic acid 1-hydroxylase from Pseudomonas acidovorans.

  Journal of bacteriology 19750101

• Aromatic aldehyde dehydrogenase from Pseudomonas putida N.C.I.B. 9869.

  Biochemical Society transactions 19750101

• Exacerbation of dapsone-induced Heinz body hemolytic anemia following treatment with methylene blue.

  The American journal of the medical sciences 19740501

• Microbial metabolism of the pyridine ring. The hydroxylation of 4-hydroxypyridine to pyridine-3,4-diol (3,4-dihydroxypyridine) by 4-hydroxypyridine-3-hydroxylase.

  The Biochemical journal 19740501

• The reduced nicotinamide-adenine dinucleotide phosphate- and oxygen-dependent N-oxygenation of trimethylamine by Pseudomonas aminovorans.

  The Biochemical journal 19720701

• Testosterone-induced hypertension in the rat.

  Endocrinology 19700501

• A histochemical and electron microscopic study of epinephrine-induced myocardial necrosis.

  Journal of molecular and cellular cardiology 19700301

• NADH-dependent synthesis of butyric acid by rabbit mammary gland mitochondrial enzymes.

  Archives of biochemistry and biophysics 19690901

• Conversion of 17-alpha-hydroxypregnenolone to dehydroepiandrosterone by adrenal homogenates of immature and adult guinea pigs.

  Steroids 19670101

• ENZYMATIC FORMATION OF CATECHOL FROM ANTHRANILIC ACID.

  The Journal of biological chemistry 19640701

• A triphosphopyridine nucleotide-specific nitrite reductase from Escherichia coli.

  The Journal of biological chemistry 19611201

• Glutaredoxin-1 mediates NADPH-dependent stimulation of calcium-dependent insulin secretion.

  Molecular endocrinology (Baltimore, Md.)