27113-22-0 | Paradol

Packsize	Purity	Availability	Price	Discounted Price
25mg	98%	in stock	$125.00	$88.00
50mg	98%	in stock	$237.00	$166.00
100mg	98%	in stock	$445.00	$312.00
250mg	98%	in stock	$988.00	$692.00

Description

• Catalog Number: AF32610
• Chemical Name: Paradol
• CAS Number: 27113-22-0
• Molecular Formula: C17H26O3
• Molecular Weight: 278.3865
• MDL Number: MFCD01736103
• SMILES: CCCCCCCC(=O)CCc1ccc(c(c1)OC)O

Computed Properties

• Complexity: 265
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 10
• XLogP3: 3.8

Literature

• Putative mycobacterial efflux inhibitors from the seeds of Aframomum melegueta.

  Journal of natural products 20120727

• Metabolism of [6]-shogaol in mice and in cancer cells.

  Drug metabolism and disposition: the biological fate of chemicals 20120401

• Extract of grains of paradise and its active principle 6-paradol trigger thermogenesis of brown adipose tissue in rats.

  Autonomic neuroscience : basic & clinical 20110426

• Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale).

  Fitoterapia 20110101

• Chemopreventive and antioxidant efficacy of (6)-paradol in 7,12-dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis.

  Pharmacological reports : PR 20100101

• Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels.

  British journal of pharmacology 20090801

• Modulation of macrophage functions by compounds isolated from Zingiber officinale.

  Planta medica 20090201

• Herbal compounds and toxins modulating TRP channels.

  Current neuropharmacology 20080301

• Cancer preventive properties of ginger: a brief review.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070501

• Induction of apoptosis and caspase-3 activation by chemopreventive [6]-paradol and structurally related compounds in KB cells.

  Cancer letters 20020308

• Antioxidative and antitumor promoting effects of [6]-paradol and its homologs.

  Mutation research 20010920

• Inhibition of epidermal growth factor-induced cell transformation and activator protein 1 activation by [6]-gingerol.

  Cancer research 20010201