-
Synthesis and structure activity relationship of imidazo[1,2-a]pyridine-8-carboxamides as a novel antimycobacterial lead series.
Bioorganic & medicinal chemistry letters 20130901
-
Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors.
Bioorganic & medicinal chemistry letters 20121215
-
Novel codrugs with GABAergic activity for dopamine delivery in the brain.
International journal of pharmaceutics 20121101
-
Discovery of 3-cyclopropylmethyl-7-(4-phenylpiperidin-1-yl)-8-trifluoromethyl[1,2,4]triazolo[4,3-a]pyridine (JNJ-42153605): a positive allosteric modulator of the metabotropic glutamate 2 receptor.
Journal of medicinal chemistry 20121025
-
Four-component cascade heteroannulation of heterocyclic ketene aminals: synthesis of functionalized tetrahydroimidazo[1,2-a]pyridine derivatives.
The Journal of organic chemistry 20121019
-
Pd(0)-catalyzed decarboxylative coupling and tandem C-H arylation/decarboxylation for the synthesis of heteroaromatic biaryls.
The Journal of organic chemistry 20121019
-
Imidazo[1,2-a]pyridines susceptible to excited state intramolecular proton transfer: one-pot synthesis via an Ortoleva-King reaction.
The Journal of organic chemistry 20120706
-
Imidazonaphthyridine systems (part 2): Functionalization of the phenyl ring linked to the pyridine pharmacophore and its replacement by a pyridinone ring produces intriguing differences in cytocidal activity.
European journal of medicinal chemistry 20120601
-
Direct arylation of imidazo[1,2-a]pyridine at C-3 with aryl iodides, bromides, and triflates via copper(I)-catalyzed C-H bond functionalization.
Organic letters 20120406
-
Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2-a]pyridines and isomeric 5,6-fused scaffolds.
Bioorganic & medicinal chemistry 20120401
-
SAR-study on a new class of imidazo[1,2-a]pyridine-based inhibitors of 5-lipoxygenase.
Bioorganic & medicinal chemistry letters 20120301
-
2-(8-Bromo-imidazo[1,2-a]pyridin-2-yl)-N'-[(E)-4-diethyl-amino-2-hy-droxy-benzyl-idene]acetohydrazide dihydrate.
Acta crystallographica. Section E, Structure reports online 20120301
-
Molecular characterization of EP6--a novel imidazo[1,2-a]pyridine based direct 5-lipoxygenase inhibitor.
Biochemical pharmacology 20120115
-
Reaction of β-lactam carbenes with 2-pyridyl isonitriles: a one-pot synthesis of 2-carbonyl-3-(pyridylamino)imidazo[1,2-a]pyridines useful as fluorescent probes for mercury ion.
The Journal of organic chemistry 20110916
-
Novel imidazo[1,2-a]pyridine based inhibitors of the IGF-1 receptor tyrosine kinase: optimization of the aniline.
Bioorganic & medicinal chemistry letters 20110815
-
Discovery of novel imidazo[1,2-a]pyridines as inhibitors of the insulin-like growth factor-1 receptor tyrosine kinase.
Bioorganic & medicinal chemistry letters 20110815
-
The vaporization enthalpies of 2- and 4-(N,N-dimethylamino)pyridine, 1,5-diazabicyclo[4.3.0]non-5-ene, 1,8-diazabicyclo[5.4.0]undec-7-ene, imidazo[1,2-a]pyridine and 1,2,4-triazolo[1,5-a]pyrimidine by correlation-gas chromatography.
The journal of physical chemistry. B 20110714
-
Ethyl 8-amino-6-bromoimidazo[1,2-a]pyridine-2-carb-oxy-late.
Acta crystallographica. Section E, Structure reports online 20110601
-
A practical two-step synthesis of imidazo[1,2-a]pyridines from N-(prop-2-yn-1-yl)pyridin-2-amines.
Chemical communications (Cambridge, England) 20110507
-
A base promoted cyclization of N-propargylaminopyridines. Synthesis of imidazo[1,2-a]pyridine derivatives.
Organic letters 20110506
-
Design, synthesis and in vitro antimicrobial evaluation of novel Imidazo[1,2-a]pyridine and imidazo[2,1-b][1,3]benzothiazole motifs.
European journal of medicinal chemistry 20110501
-
Theoretical study on phosphorescence efficiency and color tuning from orange to blue-green of Ir(III) complexes based on substituted 2-phenylimidazo[1,2-a]pyridine ligand.
Journal of computational chemistry 20110430
-
Design and synthesis of imidazopyridine analogues as inhibitors of phosphoinositide 3-kinase signaling and angiogenesis.
Journal of medicinal chemistry 20110414
-
2-Methyl-6-(trifluoro-meth-yl)imidazo[1,2-a]pyridine-3-carbonitrile.
Acta crystallographica. Section E, Structure reports online 20110301
-
Pharmacologic Treatment with GABA(B) Receptor Agonist of Methamphetamine-Induced Cognitive Impairment in Mice.
Current neuropharmacology 20110301
-
Copper(I)-mediated preparation of new pyrano[3',4':4,5]imidazo[1,2-a]pyridin-1-one compounds under mild palladium-free conditions.
Organic & biomolecular chemistry 20110221
-
Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.
Bioorganic & medicinal chemistry letters 20110101
-
A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model.
PloS one 20110101
-
Post Groebke-Blackburn multicomponent protocol: synthesis of new polyfunctional imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives as potential antimicrobial agents.
European journal of medicinal chemistry 20101201
-
Ethyl 8-(4-nitro-phen-yl)imidazo[1,2-a]pyridine-7-carboxyl-ate.
Acta crystallographica. Section E, Structure reports online 20101201
-
Pharmacophore modeling and 3D-QSAR analysis of phosphoinositide 3-kinase p110alpha inhibitors.
Journal of molecular modeling 20100901
-
Intra-periaqueductal grey microinjections of an imidazo[1,2-b]pyridazine derivative, DM2, affects rostral ventromedial medulla cell activity and shows antinociceptive effect.
Neuropharmacology 20100301
-
Modulation of carcinogen metabolizing enzymes by new fused heterocycles pendant to 5,6,7,8-tetrahydronaphthalene derivatives.
European journal of medicinal chemistry 20100201
-
Efficient one-pot synthetic protocols for iminosugar-bearing imidazo[1,2-a]pyridines from carbohydrates.
Carbohydrate research 20100126
-
3-(3-Aryloxyaryl)imidazo[1,2-a]pyridine sulfones as liver X receptor agonists.
Bioorganic & medicinal chemistry letters 20100115
-
Novel one-pot three component reaction for the synthesis of [2-(alkylsulfanyl)imidazo[1,2-a]pyridin-3-yl](aryl)methanone.
Journal of combinatorial chemistry 20100101
-
Palladium complexes of abnormal N-heterocyclic carbenes as precatalysts for the much preferred Cu-free and amine-free Sonogashira coupling in air in a mixed-aqueous medium.
Dalton transactions (Cambridge, England : 2003) 20091221
-
Structure-activity relationship study of EphB3 receptor tyrosine kinase inhibitors.
Bioorganic & medicinal chemistry letters 20091101
-
Physicochemical properties and membrane interactions of anti-apoptotic derivatives 2-(4-fluorophenyl)-3-(pyridin-4-yl)imidazo[1,2-a]pyridine depending on the hydroxyalkylamino side chain length and conformation: an NMR and ESR study.
European journal of medicinal chemistry 20090901
-
[5-(2-Fur-yl)-6-nitro-1,2,3,5,6,7-hexa-hydro-imidazo[1,2-a]pyridin-8-yl](phen-yl)methanone.
Acta crystallographica. Section E, Structure reports online 20090901
-
Discovery of imidazo[1,2-a]pyridines as potent MCH1R antagonists.
Bioorganic & medicinal chemistry letters 20090815
-
Orally active C-6 heteroaryl- and heterocyclyl-substituted imidazo[1,2-a]pyridine acid pump antagonists (APAs).
Bioorganic & medicinal chemistry letters 20090701
-
1-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-3,3-bis-(methyl-sulfan-yl)prop-2-enone monohydrate.
Acta crystallographica. Section E, Structure reports online 20090701
-
IRAK-4 inhibitors for inflammation.
Current topics in medicinal chemistry 20090501
-
Phosphonocarboxylates inhibit the second geranylgeranyl addition by Rab geranylgeranyl transferase.
The Journal of biological chemistry 20090313
-
DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: synthesis and antibacterial activity.
Bioorganic & medicinal chemistry letters 20090201
-
Discovery and optimization of imidazo[1,2-a]pyridine inhibitors of insulin-like growth factor-1 receptor (IGF-1R).
Bioorganic & medicinal chemistry letters 20090201
-
Synthesis and anticandidal activity of some imidazopyridine derivatives.
Journal of enzyme inhibition and medicinal chemistry 20081201
-
Novel imidazo[1,2-a]naphthyridinic systems (part 1): synthesis, antiproliferative and DNA-intercalating activities.
European journal of medicinal chemistry 20081101
-
Synthesis and antituberculosis activity of new hydrazide derivatives.
Archiv der Pharmazie 20081101
-
Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells.
PLoS genetics 20081101
-
IRAK-4 inhibitors. Part III: a series of imidazo[1,2-a]pyridines.
Bioorganic & medicinal chemistry letters 20080615
-
IRAK-4 inhibitors. Part II: a structure-based assessment of imidazo[1,2-a]pyridine binding.
Bioorganic & medicinal chemistry letters 20080601
-
N-(2-Phenyl-imidazo[1,2-a]pyridin-3-yl)acetamide.
Acta crystallographica. Section E, Structure reports online 20080501
-
2-Phenyl-imidazo[1,2-a]pyridine-3-carbaldehyde.
Acta crystallographica. Section E, Structure reports online 20080501
-
Imidazo[1,2-a]pyridine derivatives as inhibitors of TNF-alpha expression in T cells.
Bioorganic & medicinal chemistry 20080201
-
Switching of polymorph-dependent ESIPT luminescence of an imidazo[1,2-a]pyridine derivative.
Angewandte Chemie (International ed. in English) 20080101
-
Synthesis and biological evaluation of sulfonylhydrazone-substituted imidazo[1,2-a]pyridines as novel PI3 kinase p110alpha inhibitors.
Bioorganic & medicinal chemistry 20070901
-
Recent progress in the pharmacology of imidazo[1,2-a]pyridines.
Mini reviews in medicinal chemistry 20070901
-
Synthesis and SAR studies of potent imidazopyridine anticoccidial agents.
Bioorganic & medicinal chemistry letters 20070701
-
Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110alpha inhibitors.
Bioorganic & medicinal chemistry 20070101
-
Efficient solid-phase synthesis of a library of imidazo[1,2-a]pyridine-8-carboxamides.
Journal of combinatorial chemistry 20070101
-
Diversification of the three-component coupling of 2-aminoheterocycles, aldehydes, and isonitriles: efficient parallel synthesis of a diverse and druglike library of imidazo- and tetrahydroimidazo[1,2-a] heterocycles.
Journal of combinatorial chemistry 20070101
-
A novel series of imidazo[1,2-a]pyridine derivatives as HIF-1alpha prolyl hydroxylase inhibitors.
Bioorganic & medicinal chemistry letters 20061101
-
Synthesis and evaluation of two 18F-labeled imidazo[1,2-a]pyridine analogues as potential agents for imaging beta-amyloid in Alzheimer's disease.
Bioorganic & medicinal chemistry letters 20060601
-
8-Fluoroimidazo[1,2-a]pyridine: synthesis, physicochemical properties and evaluation as a bioisosteric replacement for imidazo[1,2-a]pyrimidine in an allosteric modulator ligand of the GABA A receptor.
Bioorganic & medicinal chemistry letters 20060315
-
The cellular phenotype of AZ703, a novel selective imidazo[1,2-a]pyridine cyclin-dependent kinase inhibitor.
Molecular cancer therapeutics 20060301
-
AZ703, an imidazo[1,2-a]pyridine inhibitor of cyclin-dependent kinases 1 and 2, induces E2F-1-dependent apoptosis enhanced by depletion of cyclin-dependent kinase 9.
Cancer research 20060101
-
Synthesis of indeno-fused derivatives of quinolizinium salts, imidazo[1,2-a]pyridine, pyrido[1,2-a]indole, and 4h-quinolizin-4-one via benzannulated enyne-allenes.
The Journal of organic chemistry 20050819
-
Fused heterocycles: synthesis of some new imidazo[1,2-a]- pyridine derivatives.
Molecules (Basel, Switzerland) 20040930
-
Identification of photoproducts from imazosulfuron by HPLC.
Biomedical chromatography : BMC 20040901
-
Studies on the synthesis and characterization of four trans-planaramineplatinum(II) complexes of the form trans-PtL(NH3)CL2 where L = 2-hydroxypyridine, 3-hydroxypyridine, imidazole, and imidazo(1,2-alpha)pyridine.
European journal of medicinal chemistry 20040801
-
Phenylpiperazinylmethylheterocycle derivatives: synthesis and dopamine receptor binding profiles.
Archiv der Pharmazie 20040701
-
Imidazo[1,2-a]pyridines. Part 2: SAR and optimisation of a potent and selective class of cyclin-dependent kinase inhibitors.
Bioorganic & medicinal chemistry letters 20040503
-
Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors.
Bioorganic & medicinal chemistry letters 20040503
-
Design and synthesis of acyclic nucleoside analogs with chlorinated imidazo[1,2-a]pyridine bases.
Nucleosides, nucleotides & nucleic acids 20031001
-
Imidazo[1,2-a]pyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisation.
Bioorganic & medicinal chemistry letters 20030915
-
Solid-phase synthesis of imidazo[1,2-a]pyridine using sodium benzenesulfinate as a traceless linker.
Organic letters 20021031
-
Synthesis and biological evaluation of new imidazo[1,2-a]pyridine derivatives designed as mefloquine analogues.
Farmaco (Societa chimica italiana : 1989) 20021001
-
Influence of 2-substituent on the activity of imidazo[1,2-a] pyridine derivatives against human cytomegalovirus.
Bioorganic & medicinal chemistry 20020401
-
3-Benzamido, ureido and thioureidoimidazo[1,2-a]pyridine derivatives as potential antiviral agents.
Chemical & pharmaceutical bulletin 20011201
-
Heterocyclization of functionalized vinylic derivatives of imidazo.
The Journal of organic chemistry 20011005
-
Solution structure of 2-(pyrido[1,2-e]purin-4-yl)amino-ethanol intercalated in the DNA duplex d(CGATCG)2.
Biochemistry 20010731
-
Synthesis of imidazo[1,2-a]pyridine derivatives as antiviral agents.
Arzneimittel-Forschung 20010101
-
A structure-activity relationship study of the affinity of selected imidazo[1,2-a]pyridine derivatives, congeners of zolpidem, for the omega 1-subtype of the benzodiazepine receptor.
Acta poloniae pharmaceutica 20010101
-
Synthesis of acyclo-C-nucleosides in the imidazo[1,2-a]pyridine and pyrimidine series as antiviral agents.
Journal of medicinal chemistry 19960705
