286411-09-4 | 1,8-Naphthyridin-4-ol, 7-chloro-2-phenyl-

Packsize	Purity	Availability	Price	Discounted Price
25mg	95%	in stock	$1,820.00	$1,274.00

Description

• Catalog Number: AB34494
• Chemical Name: 1,8-Naphthyridin-4-ol, 7-chloro-2-phenyl-
• CAS Number: 286411-09-4
• Molecular Formula: C14H9ClN2O
• Molecular Weight: 256.6871
• MDL Number: MFCD03452891
• SMILES: Clc1ccc2c(n1)nc(cc2O)c1ccccc1

Computed Properties

• Complexity: 363
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 3.4

Literature

• Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

  Nature chemical biology 20091001

• An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis.

  Blood 20090730

• Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors.

  Journal of medicinal chemistry 20051117

• Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives.

  Journal of medicinal chemistry 20040603

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419