29049-45-4 | 6-Chloro-4-pyridazinamine

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$13.00	$9.00
250mg	95%	in stock	$24.00	$17.00
1g	95%	in stock	$31.00	$22.00
5g	95%	in stock	$149.00	$105.00
10g	95%	in stock	$242.00	$170.00
25g	95%	in stock	$522.00	$366.00

Description

• Catalog Number: AB33708
• Chemical Name: 6-Chloro-4-pyridazinamine
• CAS Number: 29049-45-4
• Molecular Formula: C4H4ClN3
• Molecular Weight: 129.5477
• MDL Number: MFCD03085861
• SMILES: Nc1cnnc(c1)Cl

Upstream Synthesis Route

The synthesis of 6-Chloro-4-pyridazinamine can be achieved through the following upstream route:

1. Start with 4,6-Dichloropyridazine as the starting material.
2. Subject the 4,6-Dichloropyridazine to amination conditions by reacting it with an excess of ammonia.
3. The ammonia targets the more reactive chlorine at the 4-position due to less steric hindrance compared to the chlorine at the 6-position.
4. The reaction typically takes place under high pressure and elevated temperature conditions to facilitate the substitution reaction.
5. The end product is 6-Chloro-4-pyridazinamine, where the chlorine at the 4-position has been replaced by an amino group. The selectivity of the reaction toward the 4-position can be enhanced by the choice of solvent and reaction conditions.