298-81-7 | 9-methoxy-2H-furo[3,2-g]chromen-2-one

Packsize	Purity	Availability	Price	Discounted Price
1mg	98+%	in stock	$6.00	$4.00
100mg	>98.0%(GC)	in stock	$18.00	$12.00
1g	98+%	in stock	$21.00	$15.00
5g	95%	in stock	$29.00	$21.00
10g	95%	in stock	$48.00	$34.00
25g	95%	in stock	$117.00	$82.00

Description

• Catalog Number: AI46760
• Chemical Name: 9-methoxy-2H-furo[3,2-g]chromen-2-one
• CAS Number: 298-81-7
• Molecular Formula: C12H8O4
• Molecular Weight: 216.1895
• MDL Number: MFCD00005009
• SMILES: COc1c2oc(=O)ccc2cc2c1occ2

Computed Properties

• Complexity: 325
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• XLogP3: 1.9

Literature

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• Extracorporeal photochemotherapy.

  Journal of dermatological science 20090601

• Evidence that bergapten, independently of its photoactivation, enhances p53 gene expression and induces apoptosis in human breast cancer cells.

  Current cancer drug targets 20090601

• A new psoralen derivative with enlarged antiproliferative properties.

  Bioorganic & medicinal chemistry letters 20090515

• Regulatory T cells and extracorporeal photochemotherapy: correlation with clinical response and decreased frequency of proinflammatory T cells.

  Transplantation 20090515

• 4-Phenoxybutoxy-substituted heterocycles--a structure-activity relationship study of blockers of the lymphocyte potassium channel Kv1.3.

  European journal of medicinal chemistry 20090501

• The human oxidative DNA glycosylase NEIL1 excises psoralen-induced interstrand DNA cross-links in a three-stranded DNA structure.

  The Journal of biological chemistry 20090501

• Inhibitory effect of Poncirus trifoliate on acetylcholinesterase and attenuating activity against trimethyltin-induced learning and memory impairment.

  Bioscience, biotechnology, and biochemistry 20090501

• [Coumarins from Peucedanum harry-smithii var. subglabrum].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090501

• Oral vs. bath PUVA using 8-methoxypsoralen for chronic palmoplantar eczema.

  Photodermatology, photoimmunology & photomedicine 20090401

• Transcutaneous sampling of ciprofloxacin and 8-methoxypsoralen by electroporation (ETS technique).

  International journal of pharmaceutics 20090318

• Pyrano[2,3-e]isoindol-2-ones, new angelicin heteroanalogues.

  Bioorganic & medicinal chemistry letters 20090315

• Bath-PUVA therapy induces circulating regulatory T cells in patients with psoriasis.

  Journal of dermatological science 20090301

• Optimization of the comet assay for the sensitive detection of PUVA-induced DNA interstrand cross-links.

  Mutagenesis 20090301

• Time course for development of psoralen plus ultraviolet A erythema following oral administration of 5-methoxypsoralen.

  The British journal of dermatology 20090301

• Activated toxicity of diesel particulate extract by ultraviolet a radiation in mammalian cells: role of singlet oxygen.

  Environmental health perspectives 20090301

• Lung Carcinogenic Bioassay of CuO and TiO(2) Nanoparticles with Intratracheal Instillation Using F344 Male Rats.

  Journal of toxicologic pathology 20090301

• Brain drug-metabolizing cytochrome P450 enzymes are active in vivo, demonstrated by mechanism-based enzyme inhibition.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090201

• Constitutive expression of bergaptol O-methyltransferase in Glehnia littoralis cell cultures.

  Plant cell reports 20090201

• Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse.

  Toxicological sciences : an official journal of the Society of Toxicology 20090201

• Extracorporeal methoxsalen: new drug. Cutaneous T cell lymphoma: for rare patients, but better assessment needed.

  Prescrire international 20090201

• Tetrahydrobenzo- and benzofurobenzopyrones as a new class of potential photoreagents toward DNA.

  European journal of medicinal chemistry 20090101

• Retinyl palmitate is non-genotoxic in Chinese hamster ovary cells in the dark or after pre-irradiation or simultaneous irradiation with UV light.

  Mutation research 20090101

• Non-classical p38 map kinase functions: cell cycle checkpoints and survival.

  International journal of biological sciences 20090101

• Self-medication as adaptive plasticity: increased ingestion of plant toxins by parasitized caterpillars.

  PloS one 20090101

• Effects of an ultraviolet B radiation absorber on photocarcinogenesis in hairless albino mice.

  Skin pharmacology and physiology 20090101

• Treatment of acrodermatitis continua with topical 8-methoxypsoralen plus local narrowband ultraviolet B phototherapy.

  European journal of dermatology : EJD 20090101

• Does the clock make the poison? Circadian variation in response to pesticides.

  PloS one 20090101

• Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants.

  BMC complementary and alternative medicine 20090101

• Miescher's granulomatosis (granulomatosis disciformis chronica et progressiva) in a non-diabetic patient--case report.

  Diagnostic pathology 20090101

• Inactivation of staphylococcal virulence factors using a light-activated antimicrobial agent.

  BMC microbiology 20090101

• Phylogenetic relatedness and host plant growth form influence gene expression of the polyphagous comma butterfly (Polygonia c-album).

  BMC genomics 20090101

• In vivo tissue uptake of intravenously injected water soluble all-trans beta-carotene used as a food colorant.

  Nutrition journal 20090101

• Psoralen and bergapten: in silico metabolism and toxicophoric analysis of drugs used to treat vitiligo.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090101

• Vitiligo treatment with vitamins, minerals and polyphenol supplementation.

  Indian journal of dermatology 20090101

• Current and emerging therapy for the management of vitiligo.

  Clinical, cosmetic and investigational dermatology 20090101

• 8-Methoxypsoralen, a potent human CYP2A6 inhibitor, inhibits lung adenocarcinoma development induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice.

  Molecular medicine reports 20090101

• Effects of xanthotoxin treatment on trichothecene production in Fusarium sporotrichioides.

  Canadian journal of microbiology 20081201

• Quantitative analysis of DNA interstrand cross-links and monoadducts formed in human cells induced by psoralens and UVA irradiation.

  Analytical chemistry 20081115

• Thiopyrano[2,3-e]indol-2-ones: angelicin heteroanalogues with potent photoantiproliferative activity.

  Bioorganic & medicinal chemistry 20081115

• Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology.

  Toxicological sciences : an official journal of the Society of Toxicology 20081101

• Characterization of CYP2A13*2, a variant cytochrome P450 allele previously found to be associated with decreased incidences of lung adenocarcinoma in smokers.

  Drug metabolism and disposition: the biological fate of chemicals 20081101

• Application of chitin and chitosan as elicitors of coumarins and fluoroquinolone alkaloids in Ruta graveolens L. (common rue).

  Biotechnology and applied biochemistry 20081001

• Lipid nanoparticles as vehicles for topical psoralen delivery: solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC).

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20081001

• Lack of modifying potential of 8-methoxypsoralen in the promotion or progression stages of lung carcinogenesis in A/J female mice.

  Oncology reports 20081001

• Photoreactivity of psoralen derivatives in micelles: the roles of hydrophobicity and heavy atom substitution.

  Journal of photochemistry and photobiology. B, Biology 20080918

• Small molecular antioxidants effectively protect from PUVA-induced oxidative stress responses underlying fibroblast senescence and photoaging.

  Free radical biology & medicine 20080901

• Aflatoxin B1 detoxification by CYP321A1 in Helicoverpa zea.

  Archives of insect biochemistry and physiology 20080901

• Establishment of a bioassay model for lung cancer chemoprevention initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080901

• Automated liquid-liquid extraction based on 96-well plate format in conjunction with ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) for the quantitation of methoxsalen in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080901

• Human MLH1 protein participates in genomic damage checkpoint signaling in response to DNA interstrand crosslinks, while MSH2 functions in DNA repair.

  PLoS genetics 20080901

• Model of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromes.

  Clinical interventions in aging 20080901

• Extracorporeal photopheresis reverses experimental graft-versus-host disease through regulatory T cells.

  Blood 20080815

• Regulatory T cell-associated activity in photopheresis-induced immune tolerance in recent onset type 1 diabetes children.

  Clinical and experimental immunology 20080801

• [Contents of furanocoumarins in grapefruit juice and health foods].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20080801

• [Chemical constituents of antibacterial activity fraction of Angelica polymorpha].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080801

• Furocoumarins photolysis products induce differentiation of human erythroid cells.

  Journal of photochemistry and photobiology. B, Biology 20080724

• Isolation and identification of insecticidal components from Citrus aurantium fruit peel extract.

  Journal of agricultural and food chemistry 20080723

• Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.

  Drug metabolism and disposition: the biological fate of chemicals 20080701

• Bioassay directed identification of natural aryl hydrocarbon-receptor agonists in marmalade.

  Analytica chimica acta 20080609

• Role for CD4(+)CD25(+) T cells in inhibition of graft rejection by extracorporeal photopheresis.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080601

• Tritrophic effects of xanthotoxin on the polyembryonic parasitoid Copidosoma sosares (Hymenoptera: Encyrtidae).

  Journal of chemical ecology 20080601

• Mucocutaneous ulcerations secondary to methotrexate.

  Cutis 20080501

• LC-MS/MS for the detection of DNA interstrand cross-links formed by 8-methoxypsoralen and UVA irradiation in human cells.

  Analytical chemistry 20080415

• Impact of psoralen/UVA-treatment on survival, activation, and immunostimulatory capacity of monocyte-derived dendritic cells.

  Transplantation 20080315

• Kinase-likeness and kinase-privileged fragments: toward virtual polypharmacology.

  Journal of medicinal chemistry 20080313

• Effective biotic elicitation of Ruta graveolens L. shoot cultures by lysates from Pectobacterium atrosepticum and Bacillus sp.

  Biotechnology letters 20080301

• Controlled inactivation of recombinant viruses with vitamin B2.

  Journal of virological methods 20080301

• Different modes of inhibition of mouse Cyp2a5 and rat CYP2A3 by the food-derived 8-methoxypsoralen.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080301

• Central role of mitochondria and p53 in PUVA-induced apoptosis in human keratinocytes cell line NCTC-2544.

  Toxicology and applied pharmacology 20080215

• 'The Laundry Bag Project'--unequal distribution of dermatological healthcare resources for male and female psoriatic patients in Sweden.

  International journal of dermatology 20080201

• Detection of photogenotoxicity in skin and eye in rat with the photo comet assay.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080201

• In planta biocatalysis screen of P450s identifies 8-methoxypsoralen as a substrate for the CYP82C subfamily, yielding original chemical structures.

  Chemistry & biology 20080201

• Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts.

  European journal of pharmacology 20080128

• The increase in melanoma: are dietary furocoumarins responsible?

  Medical hypotheses 20080101

• In vivo methods for the assessment of topical drug bioavailability.

  Pharmaceutical research 20080101

• Identification of Ruta graveolens L. metabolites accumulated in the presence of abiotic elicitors.

  Biotechnology progress 20080101

• Modifications in the N-terminus of an insect cytochrome P450 enhance production of catalytically active protein in baculovirus-Sf9 cell expression systems.

  Insect biochemistry and molecular biology 20080101

• Nicotine metabolism and urinary elimination in mouse: in vitro and in vivo.

  Xenobiotica; the fate of foreign compounds in biological systems 20080101

• Topical 8-methoxypsoralen enhances the therapeutic results of targeted narrowband ultraviolet B phototherapy for plaque-type psoriasis.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20080101

• Bath PUVA and psoriasis: is a milder treatment a worse treatment?

  Dermatology (Basel, Switzerland) 20080101

• Merkel cell carcinoma of the upper extremity: case report and an update.

  World journal of surgical oncology 20080101

• Acetylation regulates WRN catalytic activities and affects base excision DNA repair.

  PloS one 20080101

• Real-time fluorescence-based detection of furanocoumarin photoadducts of DNA.

  Phytochemical analysis : PCA 20080101

• A systematic review of natural health product treatment for vitiligo.

  BMC dermatology 20080101

• Comparison of two diluents of 1% methoxsalen in the treatment of vitiligo.

  Indian journal of dermatology, venereology and leprology 20080101

• Coumarin, anthroquinone and stilbene derivatives with anticholinesterase activity.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

• PUVA-bath photochemotherapy and isotretinoin in sclerodermatous graft-versus-host disease.

  European journal of dermatology : EJD 20080101

• Inhibition on human liver cytochrome P450 3A4 by constituents of fennel (Foeniculum vulgare): identification and characterization of a mechanism-based inactivator.

  Journal of agricultural and food chemistry 20071212

• Helicoverpa zea CYP6B8 and CYP321A1: different molecular solutions to the problem of metabolizing plant toxins and insecticides.

  Protein engineering, design & selection : PEDS 20071201

• Establishment of mus skin photo-damage model by 8-MOP plus UVA irradiation.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20071201

• CYP2A13: variable expression and role in human lung microsomal metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

  The Journal of pharmacology and experimental therapeutics 20071101

• [Use of psoralen plus UV-A therapy in the autonomous community of Valencia, Spain].

  Actas dermo-sifiliograficas 20071101

• The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular senescence response phenotype.

  Experimental gerontology 20070901

• Coumarins from Peucedanum luxurians.

  Fitoterapia 20070901

• Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast.

  FEMS yeast research 20070901

• [Simultaneous determination of 5 active components in Fructus Cnidii by HPLC].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901

• [Simultaneous determination of 8-methoxypsoralen and 5-methoxypsoralen in cosmetics using LC-MS/MS].

  Se pu = Chinese journal of chromatography 20070901

• The photo comet assay--a fast screening assay for the determination of photogenotoxicity in vitro.

  Mutation research 20070815

• Cytochrome P450s in Papilio multicaudatus and the transition from oligophagy to polyphagy in the Papilionidae.

  Insect molecular biology 20070801

• A new device to study ex-vivo the effects of extracorporeal photochemotherapy on the immune system.

  Journal of photochemistry and photobiology. B, Biology 20070727

• Antimicrobial activity of the methanolic extracts and compounds from Treculia obovoidea (Moraceae).

  Journal of ethnopharmacology 20070725

• Antioxidant activity of diphenyl diselenide prevents the genotoxicity of several mutagens in Chinese hamster V79 cells.

  Mutation research 20070710

• In vivo photochemical skin micronucleus test using a sunlight simulator: detection of 8-methoxypsoralen and benzo[a]pyrene in hairless mice.

  Mutation research 20070710

• In vitro treatment of monocytes with 8-methoxypsolaren and ultraviolet A light induces dendritic cells with a tolerogenic phenotype.

  Clinical and experimental immunology 20070601

• German evidence-based guidelines for the treatment of Psoriasis vulgaris (short version).

  Archives of dermatological research 20070601

• Induction of regulatory T cells after prophylactic treatment with photopheresis in renal transplant recipients.

  Transplantation 20070527

• Burns caused by accidental overdose of photochemotherapy (PUVA).

  Burns : journal of the International Society for Burn Injuries 20070501

• Retinal toxic reactions following photopheresis.

  Archives of dermatology 20070501

• [Isolation and structure identification of chemical constituents from Saposhnikovia divaricata (Turcz.) Schischk].

  Yao xue xue bao = Acta pharmaceutica Sinica 20070501

• Changes in the dermoscopic appearance of melanocytic naevi after photochemotherapy or narrow-band ultraviolet B phototherapy.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20070401

• [Consensus document on bath-PUVA therapy. The Spanish Photobiology Group of the Spanish Academy of Dermatology and Venereology].

  Actas dermo-sifiliograficas 20070401

• Induction of apoptosis in Jurkat cells by photoexcited psoralen derivatives: Implication of mitochondrial dysfunctions and caspases activation.

  Toxicology in vitro : an international journal published in association with BIBRA 20070301

• Allelochemical induction of cytochrome P450 monooxygenases and amelioration of xenobiotic toxicity in Helicoverpa zea.

  Journal of chemical ecology 20070301

• Induction of keratinocyte apoptosis by photosensitizing chemicals plus UVA.

  Journal of dermatological science 20070201

• The effect of extracorporeal photoimmunotherapy (ECP) on serum TNF-a level in chronic graft versus host disease (GvHD).

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20070201

• Local narrowband UVB phototherapy vs. local PUVA in the treatment of chronic hand eczema.

  Photodermatology, photoimmunology & photomedicine 20070201

• Photochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor.

  Toxicological sciences : an official journal of the Society of Toxicology 20070101

• Inhibition of nicotine metabolism by methoxysalen: Pharmacokinetic and pharmacological studies in mice.

  The Journal of pharmacology and experimental therapeutics 20070101

• Can dietary furanocoumarin ingestion enhance the erythemal response during high-dose UVA1 therapy?

  Journal of the American Academy of Dermatology 20070101

• Photodegradation of folic acid during extracorporeal photopheresis.

  The British journal of dermatology 20070101

• CD30+ large cell transformation of mycosis fungoides after psoralen plus ultraviolet A photochemotherapy.

  The British journal of dermatology 20070101

• [Inhibitory effects of 11 coumarin compounds against growth of human bladder carcinoma cell line E-J in vitro].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20070101

• Efficient sequence-directed psoralen targeting using pseudocomplementary Peptide nucleic acids.

  Bioconjugate chemistry 20070101

• Improved generation of anti-tumor immunity by antigen dose limitation.

  Journal of immune based therapies and vaccines 20070101

• Ethnoveterinary medicines used for ruminants in British Columbia, Canada.

  Journal of ethnobiology and ethnomedicine 20070101

• The evolutionary history of cytochrome P450 genes in four filamentous Ascomycetes.

  BMC evolutionary biology 20070101

• Transposable elements are enriched within or in close proximity to xenobiotic-metabolizing cytochrome P450 genes.

  BMC evolutionary biology 20070101

• Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans.

  Genome biology 20070101

• In vitro phototoxicity test using artificial skin with melanocytes.

  Photodermatology, photoimmunology & photomedicine 20070101

• The effect of psoralen plus ultraviolet A in vitro in HUT-78 enhances by 5-aminolevulinic acid.

  Photodermatology, photoimmunology & photomedicine 20070101

• [Studies on the chemical constituents of the aerial parts of Seseli mairei].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070101

• Extracorporeal photopheresis as a treatment for patients with severe, refractory atopic dermatitis.

  Dermatology (Basel, Switzerland) 20070101

• Soluble tumour necrosis factor-alpha receptor type 1 as a biomarker of response to phototherapy in patients with psoriasis.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20070101

• Ocular manifestations of chronic graft-versus-host disease in patients treated with extracorporeal photochemotherapy.

  European journal of ophthalmology 20070101

• Inhibition of acetylcholinesterase by extracts and constituents from Angelica archangelica and Geranium sylvaticum.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

• Tissue and life stage specificity of glutathione S-transferase expression in the Hessian fly, Mayetiola destructor: implications for resistance to host allelochemicals.

  Journal of insect science (Online) 20070101

• CYP2A13 expressed in human bladder metabolically activates 4-aminobiphenyl.

  International journal of cancer 20061201

• 8-Methoxypsoralen cream plus targeted narrowband ultraviolet B for psoriasis.

  Photodermatology, photoimmunology & photomedicine 20061201

• [How I was enticed into molecular toxicology].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20061201

• Synthesis and biological in vitro evaluation of novel PEG-psoralen conjugates.

  Biomacromolecules 20061201

• Monoamine oxidase inhibitory coumarins from the aerial parts of Dictamnus albus.

  Archives of pharmacal research 20061201

• Parsnip webworms and host plants at home and abroad: trophic complexity in a geographic mosaic.

  Ecology 20061201

• [Studies on chemical constituents from fruits of Paliurus ramosissimus].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061201

• Recreational use of Psoralens to fortify skin tanning.

  Burns : journal of the International Society for Burn Injuries 20061101

• Photo-chemically induced DNA effects in the comet assay with epidermal cells of SKH-1 mice after a single oral administration of different fluoroquinolones and 8-methoxypsoralen in combination with exposure to UVA.

  Mutation research 20061010

• UVA-activated 8-methoxypsoralen (PUVA) causes G2/M cell cycle arrest in Karpas 299 T-lymphoma cells.

  Journal of photochemistry and photobiology. B, Biology 20061002

• Antimycobacterial activity of geranylated furocoumarins from Tetradium daniellii.

  Planta medica 20061001

• Randomized, double-blind comparison of 1 mg/L versus 5 mg/L methoxsalen bath-PUVA therapy for chronic plaque-type psoriasis.

  Journal of the American Academy of Dermatology 20061001

• A deficit of detoxification enzymes: pesticide sensitivity and environmental response in the honeybee.

  Insect molecular biology 20061001

• Clastogenicity, photo-clastogenicity or pseudo-photo-clastogenicity: Genotoxic effects of zinc oxide in the dark, in pre-irradiated or simultaneously irradiated Chinese hamster ovary cells.

  Mutation research 20060905

• Use of the yeast Saccharomyces cerevisiae as a pre-screening approach for assessment of chemical-induced phototoxicity.

  Toxicology in vitro : an international journal published in association with BIBRA 20060901

• Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060901

• [Penetration kinetics of xanthotoxin across human skin and stratum corneum].

  Yao xue xue bao = Acta pharmaceutica Sinica 20060901

• 8-Methoxypsoralen and neurological disorders: from dysosmia to migraine.

  Photodermatology, photoimmunology & photomedicine 20060801

• Characterization of hepatic drug-metabolizing activities of Bama miniature pigs (Sus scrofa domestica): comparison with human enzyme analogs.

  Comparative medicine 20060801

• Chemical constituents of the root of Dystaenia takeshimana and their anti-inflammatory activity.

  Archives of pharmacal research 20060801

• Solar simulator-induced phototoxicity of the furoquinoline alkaloid dictamnine compared to 8-methoxypsoralen and 5-methoxypsoralen.

  Planta medica 20060801

• Antigenotoxic effects of three essential oils in diploid yeast (Saccharomyces cerevisiae) after treatments with UVC radiation, 8-MOP plus UVA and MMS.

  Mutation research 20060714

• New furan side tetracyclic allopsoralen derivatives: synthesis and photobiological evaluation.

  Journal of medicinal chemistry 20060713

• Drug-drug interaction after single oral doses of the furanocoumarin methoxsalen and cyclosporine.

  Journal of clinical pharmacology 20060701

• Assessment of the phototoxic hazard of some essential oils using modified 3T3 neutral red uptake assay.

  Toxicology in vitro : an international journal published in association with BIBRA 20060601

• Antifungal and antibacterial activities of Mexican tarragon (Tagetes lucida).

  Journal of agricultural and food chemistry 20060517

• The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes.

  Drug metabolism and disposition: the biological fate of chemicals 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• PUVA treatment of the nasal cavity improves the clinical symptoms of allergic rhinitis and inhibits the immediate-type hypersensitivity reaction in the skin.

  Journal of photochemistry and photobiology. B, Biology 20060403

• Phototoxic activity of a thiophene polyacetylene from Leuzea carthamoides.

  Fitoterapia 20060401

• A method for quantitative determination of furanocoumarins in capsules and tablets of phytochemical preparations.

  Chemical & pharmaceutical bulletin 20060401

• Extracorporeal photochemotherapy: a safety and tolerability pilot study with preliminary efficacy results in refractory relapsing-remitting multiple sclerosis.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20060401

• [Incidence of drug-induced photosensitization during phototherapy].

  Annales de dermatologie et de venereologie 20060401

• Dose dependent inhibitory effects of dietary 8-methoxypsoralen on NNK-induced lung tumorigenesis in female A/J mice.

  Cancer letters 20060328

• An in vivo analysis of MMC-induced DNA damage and its repair.

  Carcinogenesis 20060301

• Efficacy of 8-methoxypsoralen vs. 5-methoxypsoralen plus ultraviolet A therapy in patients with mycosis fungoides.

  The British journal of dermatology 20060301

• Inhibition of CYP6B1-mediated detoxification of xanthotoxin by plant allelochemicals in the black swallowtail (Papilio polyxenes).

  Journal of chemical ecology 20060301

• Cytochrome P450-mediated metabolism of xanthotoxin by Papilio multicaudatus.

  Journal of chemical ecology 20060301

• A QSAR model for in silico screening of MAO-A inhibitors. Prediction, synthesis, and biological assay of novel coumarins.

  Journal of medicinal chemistry 20060209

• Paired comparison of bathwater versus oral delivery of 8-methoxypsoralen in psoralen plus ultraviolet: A therapy for chronic palmoplantar psoriasis.

  Photodermatology, photoimmunology & photomedicine 20060201

• Formation of 8-hydroxy-2'-deoxyguanosine in the DNA of cultured human keratinocytes by clinically used doses of narrowband and broadband ultraviolet B and psoralen plus ultraviolet A.

  Cancer science 20060201

• Psoralen cream plus ultraviolet A photochemotherapy (PUVA cream): our experience.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20060201

• Psoralen-ultraviolet A vs. narrow-band ultraviolet B phototherapy for the treatment of vitiligo.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20060201

• [Studies on chemical constituents in roots of Heracleum rapula].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060201

• Differential sensitivity of T lymphocytes and hematopoietic precursor cells to photochemotherapy with 8-methoxypsoralen and ultraviolet A light.

  Annals of hematology 20060101

• Long-term results of topical PUVA in necrobiosis lipoidica.

  Clinical and experimental dermatology 20060101

• Protective effect of furocoumarins against 254-nm ultraviolet in Staphylococcus aureus.

  Current microbiology 20060101

• Maturation state of dendritic cells during the extracorporeal photopheresis and its relevance for the treatment of chronic graft-versus-host disease.

  Transfusion 20060101

• Potential mechanisms of photopheresis in hematopoietic stem cell transplantation.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20060101

• Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects.

  Journal of natural products 20060101

• Nicotine and non-nicotine smoking cessation pharmacotherapies.

  Cardiology in review 20060101

• Effects of psoralen-UV-A-Turban in alopecia areata.

  Skinmed 20060101

• Variations in content of active ingredients causing drug interactions in grapefruit juice products sold in California.

  Drug metabolism and drug interactions 20060101

• Assessment of 8-methoxypsoralen and ultraviolet a light effects on human stroma generation and function.

  Acta haematologica 20060101

• Broad-range bacterial and fungal DNA amplification on vitreous humor from suspected endophthalmitis patients.

  Molecular diagnosis & therapy 20060101

• The use of topical PUVA for palmoplantar dermatoses.

  The Journal of dermatological treatment 20060101

• Extracorporeal photophoresis: an evidence-based analysis.

  Ontario health technology assessment series 20060101

• Genetic polymorphism of CYP2A6 as one of the potential determinants of tobacco-related cancer risk.

  Biochemical and biophysical research communications 20051209

• Inhibition of interferon-gamma signaling by a mercurio-substituted dihydropsoralen in murine keratinocytes.

  Biochemical pharmacology 20051205

• Increased production of soluble HLA-G molecules in stimulated peripheral blood mononuclear cells following extracorporeal photopheresis: is it a mechanism involved in the therapeutic effect of the procedure?

  Journal of clinical apheresis 20051201

• Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung adenomas.

  Carcinogenesis 20051101

• Natural compounds,fraxin and chemicals structurally related to fraxin protect cells from oxidative stress.

  Experimental & molecular medicine 20051031

• Determination of the minimal phototoxic dose and colorimetry in psoralen plus ultraviolet A radiation therapy.

  Photodermatology, photoimmunology & photomedicine 20051001

• Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.

  Current drug metabolism 20051001

• Phototoxicity of new psoralen-containing gels and creams versus bath PUVA.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20051001

• Regulation of an insect cytochrome P450 monooxygenase gene (CYP6B1) by aryl hydrocarbon and xanthotoxin response cascades.

  Gene 20050926

• Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen.

  Nature structural & molecular biology 20050901

• Narrow-band UVB311 nm vs. broad-band UVB therapy in combination with topical calcipotriol vs. placebo in vitiligo.

  International journal of dermatology 20050901

• Alopecia areata treatment with a phototoxic dose of UVA and topical 8-methoxypsoralen.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20050901

• [Study on using in vitro 3T3 neutral red uptake to test phototoxicity].

  Wei sheng yan jiu = Journal of hygiene research 20050901

• Characterization of microsomal cytochrome P450-dependent monooxygenases in the rat olfactory mucosa.

  Drug metabolism and disposition: the biological fate of chemicals 20050801

• Accumulation of biologically active furanocoumarins in agitated cultures of Ruta graveolens L. and Ruta graveolens ssp. divaricata (Tenore) Gams.

  Die Pharmazie 20050801

• Melanogenesis stimulation in murine b16 melanoma cells by umberiferae plant extracts and their coumarin constituents.

  Biological & pharmaceutical bulletin 20050701

• Therapeutic and prophylactic effects of PUVA photochemotherapy on atopic dermatitis-like lesions in NC/Nga mice.

  Photodermatology, photoimmunology & photomedicine 20050601

• Intravenous infusion of syngeneic apoptotic cells by photopheresis induces antigen-specific regulatory T cells.

  Journal of immunology (Baltimore, Md. : 1950) 20050515

• Synthesis and photochemotherapeutic activity of thiopyrano[2,3-e]indol-2-ones.

  Bioorganic & medicinal chemistry letters 20050502

• Quantitative echographic analysis of photochemotherapy on systemic sclerosis skin.

  Archives of dermatological research 20050501

• [Methoxypsoralene plus UVA and unexpected side effects].

  Annales de dermatologie et de venereologie 20050501

• Evaluation of phototoxic and photoallergic potentials of 13 compounds by different in vitro and in vivo methods.

  Journal of photochemistry and photobiology. B, Biology 20050404

• PUVA-gel vs. PUVA-bath therapy for severe recalcitrant palmoplantar dermatoses. A randomized, single-blinded prospective study.

  Photodermatology, photoimmunology & photomedicine 20050401

• Small-scale extracorporeal photopheresis for the treatment of cutaneous T-cell lymphoma: a report of 3 cases.

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20050401

• Evaluation of time-dependent response to psoralen plus UVA (PUVA) treatment with topical 8-methoxypsoralen (8-MOP) gel in palmoplantar dermatoses.

  International journal of dermatology 20050401

• Ile115Leu mutation in the SRS1 region of an insect cytochrome P450 (CYP6B1) compromises substrate turnover via changes in a predicted product release channel.

  Protein engineering, design & selection : PEDS 20050401

• Antioxidant activity of citrus limonoids, flavonoids, and coumarins.

  Journal of agricultural and food chemistry 20050323

• Effects of 8-methoxypsoralen on cytochrome P450 2A13.

  Carcinogenesis 20050301

• 5-(3-Phenylpropoxy)psoralen and 5-(4-phenylbutoxy)psoralen: mechanistic studies on phototoxicity.

  Die Pharmazie 20050301

• Natural furocoumarins as inducers and inhibitors of cytochrome P450 1A1 in rat hepatocytes.

  Biochemical pharmacology 20050215

• Phototoxicity, distribution and kinetics of association of UVA-activated chlorpromazine, 8-methoxypsoralen, and 4,6,4'-trimethylangelicin in Jurkat cells.

  Journal of photochemistry and photobiology. B, Biology 20050201

• Phototoxicity study of a ketoprofen poultice in guinea pigs.

  The Journal of toxicological sciences 20050201

• The protective effect of alpha-lipoic acid against oxidative damage in rabbit conjunctiva and cornea exposed to ultraviolet radiation.

  Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20050101

• Accumulation of biologically active furanocoumarins in Ruta graveolens ssp. divaricata (Tenore) Gams in vitro culture.

  Die Pharmazie 20050101

• Antiapoptotic role of p38 mitogen activated protein kinase in Jurkat T cells and normal human T lymphocytes treated with 8-methoxypsoralen and ultraviolet-A radiation.

  Apoptosis : an international journal on programmed cell death 20050101

• Analysis of p53 tumor suppressor gene, H-ras protooncogene and proliferating cell nuclear antigen (PCNA) in squamous cell carcinomas of HRA/Skh mice following exposure to 8-methoxypsoralen (8-MOP) and UVA radiation (PUVA therapy).

  Toxicologic pathology 20050101

• Rapid construction of a dendritic cell vaccine through physical perturbation and apoptotic malignant T cell loading.

  Journal of immune based therapies and vaccines 20050101

• Mechanism of action of 4-hydroxymethyl-1,6,8-trimethylfuro[2,3-h]quinolin-2(1H)-one, a very active angular furocoumarin-like sensitizer.

  Photochemistry and photobiology 20050101

• An improved method of elimination of DNA from PCR reagents.

  Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology 20050101

• Bath-water PUVA therapy with 8-methoxypsoralen in mycosis fungoides.

  Acta dermato-venereologica 20050101

• Effects of 5-methoxypsoralen (5-MOP) on arylamine N-acetyltransferase activity in the stomach and colon of rats and human stomach and colon tumor cell lines.

  In vivo (Athens, Greece) 20050101

• The effect of octreotide against oxidative damage in photosensitized conjunctiva and cornea of rabbits.

  Documenta ophthalmologica. Advances in ophthalmology 20050101

• [Comparative study of the treatment of psoriasis plaques with PUVA baths and narrow-band UVA (311 nm)].

  Actas dermo-sifiliograficas 20050101

• Preparative isolation and purification of bergapten and imperatorin from the medicinal plant Cnidium monnieri using high-speed counter-current chromatography by stepwise increasing the flow-rate of the mobile phase.

  Journal of chromatography. A 20041217

• Development of a PCR method for mycoplasma testing of Chinese hamster ovary cell cultures used in the manufacture of recombinant therapeutic proteins.

  Biologicals : journal of the International Association of Biological Standardization 20041201

• A pimpinellin monomer and dimer isolated from the roots of Esenbeckia grandiflora.

  Acta crystallographica. Section C, Crystal structure communications 20041201

• Biological consequences of 8-methoxypsoralen-photoinduced lesions: sequence-specificity of mutations and preponderance of T to C and T to a mutations.

  The Journal of investigative dermatology 20041201

• Comparison of oral psoralen-UV-A with a portable tanning unit at home vs hospital-administered bath psoralen-UV-A in patients with chronic hand eczema: an open-label randomized controlled trial of efficacy.

  Archives of dermatology 20041201

• 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica.

  Acta pharmaceutica (Zagreb, Croatia) 20041201

• Reduction of treatment frequency and UVA dose does not substantially compromise the antipsoriatic effect of oral psoralen-UVA.

  Journal of the American Academy of Dermatology 20041101

• A method for fast determination of psoralens in oral solutions of phytomedicines using liquid chromatography.

  Journal of pharmaceutical and biomedical analysis 20041029

• Psoralen derivatives and longwave ultraviolet irradiation are active in vitro against human melanoma cell line.

  Journal of photochemistry and photobiology. B, Biology 20041025

• Disposition of 4,6,4'-trimethylangelicin in mice maintained in the dark and after UVA irradiation.

  Farmaco (Societa chimica italiana : 1989) 20041001

• Conserved regulatory elements in the promoters of two allelochemical-inducible cytochrome P450 genes differentially regulate transcription.

  Insect biochemistry and molecular biology 20041001

• Genetic variation in primary metabolites of Pastinaca sativa; can herbivores act as selective agents?

  Journal of chemical ecology 20041001

• Molecular analysis of CYP321A1, a novel cytochrome P450 involved in metabolism of plant allelochemicals (furanocoumarins) and insecticides (cypermethrin) in Helicoverpa zea.

  Gene 20040901

• Corynebacterium jeikeium sepsis after 8-methoxypsolaren photopheresis for cutaneous T-cell lymphoma.

  Diagnostic microbiology and infectious disease 20040901

• Drug-drug interactions of Z-338, a novel gastroprokinetic agent, with terfenadine, comparison with cisapride, and involvement of UGT1A9 and 1A8 in the human metabolism of Z-338.

  European journal of pharmacology 20040823

• Transcription of a lepidopteran cytochrome P450 promoter is modulated by multiple elements in its 5' UTR and repressed by 20-hydroxyecdysone.

  Insect molecular biology 20040801

• [Study on coumarin compounds from Exocarpium Citri Grandis].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040801

• Insecticidal effect of phthalides and furanocoumarins from Angelica acutiloba against Drosophila melanogaster.

  Journal of agricultural and food chemistry 20040714

• Pharmacotherapy of pompholyx.

  Expert opinion on pharmacotherapy 20040701

• The optimal time to determine the minimal phototoxic dose in skin photosensitized by topical 8 methoxypsoralen.

  The British journal of dermatology 20040701

• Generalization of a habituated feeding deterrent response to unrelated antifeedants following prolonged exposure in a generalist herbivore, Trichoplusia ni.

  Journal of chemical ecology 20040701

• 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits cell proliferation through arylhydrocarbon receptor-mediated G1 arrest in SK-N-SH human neuronal cells.

  Neuroscience letters 20040603

• Phytotoxins from the leaves of Ruta graveolens.

  Journal of agricultural and food chemistry 20040602

• Extracorporeal photoimmunotherapy for the treatment of steroid refractory progressive chronic graft-versus-host disease.

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20040601

• Inhibition of DNA polymerization and antifungal specificity of furanocoumarins present in traditional medicines.

  Photochemistry and photobiology 20040601

• Narrowband UVB and cream psoralen-UVA combination therapy for plaque-type psoriasis.

  Journal of the American Academy of Dermatology 20040501

• Rapidly progressive dementia due to Mycobacterium neoaurum meningoencephalitis.

  Emerging infectious diseases 20040501

• UVA activated 8-MOP and chlorpromazine inhibit release of TNF-alpha by post-transcriptional regulation.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20040401

• The role of calcium, calcium-activated K+ channels, and tyrosine/kinase in psoralen-evoked responses in human melanoma cells.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040401

• Caspase-9 is the upstream caspase activated by 8-methoxypsoralen and ultraviolet-A radiation treatment of Jurkat T leukemia cells and normal T lymphocytes.

  Haematologica 20040401

• The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways.

  The EMBO journal 20040310

• Furanocoumarin biosynthesis in Ammi majus L. Cloning of bergaptol O-methyltransferase.

  European journal of biochemistry 20040301

• Identification of variable amino acids in the SRS1 region of CYP6B1 modulating furanocoumarin metabolism.

  Archives of biochemistry and biophysics 20040201

• Cinnamic acid 4-hydroxylase mechanism-based inactivation by psoralen derivatives: cloning and characterization of a C4H from a psoralen producing plant-Ruta graveolens-exhibiting low sensitivity to psoralen inactivation.

  Archives of biochemistry and biophysics 20040201

• Phytochemical studies and effect on urine volume of Glossostemon bruguieri Desf. constituents.

  Indian journal of experimental biology 20040201

• Theoretical study on the excited states of psoralen compounds bonded to a thymine residue.

  Journal of computational chemistry 20040130

• Ultraviolet light-induced regulatory (suppressor) T cells: an approach for promoting induction of operational allograft tolerance?

  Transplantation 20040115

• Orally administered Polypodium leucotomos extract decreases psoralen-UVA-induced phototoxicity, pigmentation, and damage of human skin.

  Journal of the American Academy of Dermatology 20040101

• Comparison of localized high-dose UVA1 irradiation versus topical cream psoralen-UVA for treatment of chronic vesicular dyshidrotic eczema.

  Journal of the American Academy of Dermatology 20040101

• UVA/UVA1 phototherapy and PUVA photochemotherapy in connective tissue diseases and related disorders: a research based review.

  BMC dermatology 20040101

• Phototoxicity of protoporphyrin IX, diarginine diprotoporphyrinate and N,N-diphenylalanyl protoporphyrin toward human fibroblasts and keratinocytes in vitro: effect of 5-methoxypsoralen.

  Photochemistry and photobiology 20040101

• [On the mechanism of adaptive response in human cells].

  Radiatsionnaia biologiia, radioecologiia 20040101

• Antiproliferative effect of Angelica archangelica fruits.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

• Genetics of tobacco use.

  Tobacco induced diseases 20040101

• Methoxsalen with ultraviolet A therapy (PUVA).

  Report on carcinogens : carcinogen profiles 20040101

• Chromatographic determination of the association constant between 8-methoxypsoralen and modified beta-cyclodextrin: protective effect of hydroxypropyl-beta-cyclodextrin on 8-methoxypsoralen toxicity in human keratinocytes.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031225

• Determination of 8-methoxypsoralen in human plasma, and microdialysates using liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031225

• The evolution of current medical and popular attitudes toward ultraviolet light exposure: part 3.

  Journal of the American Academy of Dermatology 20031201

• The effect of methoxsalen on nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism in vivo.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20031201

• On the photobiological properties of chimeras combining quaternary ammonium derivatives of retinoic amides and psoralen. A study with cultured human keratinocytes.

  Photochemistry and photobiology 20031201

• Cytotoxic activity of coumarins from the fruits of Cnidium monnieri on leukemia cell lines.

  Planta medica 20031201

• LC determination of impurities in methoxsalen drug substance: isolation and identification of isopimpinellin as a major impurity by atmospheric pressure chemical ionization LC/MS and NMR.

  Journal of pharmaceutical and biomedical analysis 20031124

• Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice.

  Cancer research 20031115

• Oxidative stress-related mechanisms are associated with xenobiotics exerting excess toxicity to Fanconi anemia cells.

  Environmental health perspectives 20031101

• Ultraviolet irradiation induces apoptosis in human immature, but not in skin mast cells.

  The Journal of investigative dermatology 20031001

• Long-term growth arrest of PUVA-treated fibroblasts in G2/M in the absence of p16(INK4a) p21(CIP1) or p53.

  Experimental dermatology 20031001

• [Molecular basis of UVA-induced skin aging and arotinoid ethyl ester protection].

  Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20031001

• Diversity of selective environmental substrates for human cytochrome P450 2A6: alkoxyethers, nicotine, coumarin, N-nitrosodiethylamine, and N-nitrosobenzylmethylamine.

  Toxicology letters 20030915

• Metabolism of linear and angular furanocoumarins by Papilio polyxenes CYP6B1 co-expressed with NADPH cytochrome P450 reductase.

  Insect biochemistry and molecular biology 20030901

• Functional expression of cinnamate 4-hydroxylase from Ammi majus L.

  Phytochemistry 20030901

• Novel pyrone side tetracyclic psoralen derivatives: synthesis and photobiological evaluation.

  Journal of medicinal chemistry 20030828

• Pyrrolo[2,3-h]quinolinones: synthesis and photochemotherapic activity.

  Bioorganic & medicinal chemistry letters 20030818

• Mechanisms of action of extracorporeal photochemotherapy.

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20030801

• Vitiligo therapy: where are we now?

  Journal of drugs in dermatology : JDD 20030801

• 8-Methoxypsoralen-induced dysosmia.

  Photodermatology, photoimmunology & photomedicine 20030801

• Molecular docking of substrates and inhibitors in the catalytic site of CYP6B1, an insect cytochrome p450 monooxygenase.

  Protein engineering 20030801

• [Photopheresis: a permanent promise or reality?].

  Anales de medicina interna (Madrid, Spain : 1984) 20030801

• Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: study with cDNA-expressed systems of the rat.

  Drug metabolism and disposition: the biological fate of chemicals 20030701

• An intraindividual comparative study of psoralen-UVA erythema induced by bath 8-methoxypsoralen and 4, 5', 8-trimethylpsoralen.

  Journal of the American Academy of Dermatology 20030701

• An intraindividual study of the characteristics of erythema induced by bath and oral methoxsalen photochemotherapy and narrowband ultraviolet B.

  Photochemistry and photobiology 20030701

• Effect of 5-methoxypsoralen (5-MOP) on cell apoptosis and cell cycle in human hepatocellular carcinoma cell line.

  Toxicology in vitro : an international journal published in association with BIBRA 20030601

• Treatment of persistent severe atopic dermatitis in 113 Japanese patients with oral psoralen photo-chemotherapy.

  The Journal of dermatology 20030601

• Decreasing smoking behaviour and risk through CYP2A6 inhibition.

  Drug discovery today 20030601

• Dietary intakes of vitamins A, C, and E and risk of melanoma in two cohorts of women.

  British journal of cancer 20030506

• Cytochrome P450 expression and testosterone metabolism in the liver of deer.

  Toxicology 20030501

• Phenotype matching in wild parsnip and parsnip webworms: causes and consequences.

  Evolution; international journal of organic evolution 20030401

• Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links.

  Journal of cell science 20030301

• Narrowband UV-B (TL-01) phototherapy vs oral 8-methoxypsoralen psoralen-UV-A for the treatment of chronic plaque psoriasis.

  Archives of dermatology 20030301

• The time course of topical PUVA erythema following 15- and 5-minute methoxsalen immersion.

  Archives of dermatology 20030301

• 8-Methoxypsoralen and long-wave ultraviolet A inhibit the release of proinflammatory mediators and cytokines from human Fc epsilon RI+ cells: an in vitro study.

  Journal of photochemistry and photobiology. B, Biology 20030301

• Characterization of furanocoumarin metabolites in parsnip webworm, Depressaria pastinacella.

  Journal of chemical ecology 20030301

• Transcriptional response elements in the promoter of CYP6B1, an insect P450 gene regulated by plant chemicals.

  Biochimica et biophysica acta 20030217

• Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid.

  Journal of agricultural and food chemistry 20030212

• Extracorporeal photopheresis technical aspects.

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20030201

• l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes.

  Xenobiotica; the fate of foreign compounds in biological systems 20030201

• Skin permeation of 5-methoxypsoralen from topical dosage forms.

  Drug development and industrial pharmacy 20030201

• PUVA-induced lichen planus.

  The Journal of dermatology 20030201

• Photo(chemo) therapy for vitiligo.

  Photodermatology, photoimmunology & photomedicine 20030201

• Anaphylaxis to 8-methoxypsoralen during photochemotherapy.

  Photodermatology, photoimmunology & photomedicine 20030201

• Effect of psoralens on Fenton-like reaction generating reactive oxygen species.

  Biopolymers 20030101

• Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes.

  Archives of biochemistry and biophysics 20030101

• HPLC-NMR/HPLC-MS analysis of the bark extract of Stauranthus perforatus.

  Phytochemical analysis : PCA 20030101

• Relationship between DNA repair capacity and resistance to genotoxins in four human cell lines.

  Cancer detection and prevention 20030101

• In vitro and in vivo study of 5-methoxypsoralen skin concentration after topical application.

  Skin pharmacology and applied skin physiology 20030101

• Reproductive toxicity of the psoralens.

  Pediatric pathology & molecular medicine 20030101

• Photocarcinogenesis in the Tg.AC mouse: lomefloxacin and 8-methoxypsoralen.

  Photochemistry and photobiology 20030101

• High plasma levels of 8-methoxypsoralen following bath water delivery in dermatological patients.

  Skin pharmacology and applied skin physiology 20030101

• In silico rationalization of the structural and physicochemical requirements for photobiological activity in angelicine derivatives and their heteroanalogues.

  Journal of computer-aided molecular design 20030101

• Detection of enhanced monohydroxyeicosatetraenoic acid and F2-isoprostane levels in human plasma samples after extracorporeal photoimmunotherapy.

  Skin pharmacology and applied skin physiology 20030101

• Methoxypsoralen-induced sleep disorder.

  Dermatology (Basel, Switzerland) 20030101

• The treatment of cutaneous T-cell lymphoma with photopheresis.

  Dermatologic therapy 20030101

• Photoaging as a consequence of natural and therapeutic ultraviolet irradiation--studies on PUVA-induced senescence-like growth arrest of human dermal fibroblasts.

  Experimental gerontology 20030101

• Photopheresis. Therapeutic potential in preventing restenosis after percutaneous transluminal coronary angioplasty.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101

• The furanocoumarins in the roots of Heracleum sibiricum L.

  Acta poloniae pharmaceutica 20030101

• The contribution of cytochrome P450 to the metabolism of tegafur in human liver.

  Drug metabolism and pharmacokinetics 20030101

• CYP6B cytochrome p450 monooxygenases from Papilio canadensis and Papilio glaucus: potential contributions of sequence divergence to host plant associations.

  Insect molecular biology 20021201

• In vitro migration of melanoblasts requires matrix metalloproteinase-2: implications to vitiligo therapy by photochemotherapy.

  Pigment cell research 20021201

• Augmentation of monocyte interleukin-8 production by psoralen/UVA-treated CD4+ T cells.

  Experimental dermatology 20021201

• Stimulation of melanoblast pigmentation by 8-methoxypsoralen:the involvement of microphthalmia-associated transcription factor, the protein kinase a signal pathway, and proteasome-mediated degradation.

  The Journal of investigative dermatology 20021201

• Constituents of the fruits and leaves of Euodia daniellii.

  Archives of pharmacal research 20021201

• Effects of sphondin, isolated from Heracleum laciniatum, on IL-1beta-induced cyclooxygenase-2 expression in human pulmonary epithelial cells.

  Life sciences 20021129

• Validation of a microdialysis-gas chromatographic-mass spectrometric method to assess 8-methoxypsoralen in psoriatic patient dermis.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021115

• Spatial distribution of 8-methoxypsoralen penetration into human skin after systemic or topical administration.

  British journal of clinical pharmacology 20021101

• Comparison of different decontamination methods for reagents to detect low concentrations of bacterial 16S DNA by real-time-PCR.

  Molecular biotechnology 20021101

• Apoptosis in leukocytes induced by UVA in the presence of 8-methoxypsoralen, chlorpromazine or 4,6,4'-trimethylangelicin.

  Journal of photochemistry and photobiology. B, Biology 20021101

• Determination of 5-methoxypsoralen in human serum.

  Journal of pharmaceutical and biomedical analysis 20021015

• Phytochemical and pharmacological studies on Sideritis taurica Stephan ex Wild.

  Journal of ethnopharmacology 20021001

• DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein.

  Human molecular genetics 20021001

• [Study on point mutations in mitochondrial DNA control region for replication DLP(6) of cultured dermal fibroblast with 8-MOP/UVA treatment].

  Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20021001

• Photochemotherapy of vascular cells with 8-methoxypsoralen and visible light: differential effects on endothelial and smooth muscle cells.

  Photodermatology, photoimmunology & photomedicine 20021001

• Excited singlet state and photoionization of 8-methoxypsoralen. Picosecond transient absorption study.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20021001

• Tea: not immoral, illegal, or fattening, but is it innocuous?

  Lancet (London, England) 20020914

• Micronucleus evaluation in mitogen-stimulated lymphocytes of PUVA treated patients.

  The Tohoku journal of experimental medicine 20020901

• Changes in skin physiology during bath PUVA therapy.

  The British journal of dermatology 20020701

• Methoxsalen stimulates electrogenic Cl- secretion in the mouse jejunum.

  Experimental physiology 20020701

• A melanocyte-keratinocyte coculture model to assess regulators of pigmentation in vitro.

  Analytical biochemistry 20020615

• Severe influenzalike symptoms associated with methoxsalen photochemotherapy.

  Archives of dermatology 20020601

• Transimmunization and the evolution of extracorporeal photochemotherapy.

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20020601

• T cell clonality and the effect of photopheresis in systemic sclerosis and graft versus host disease.

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20020601

• Extracorporeal photochemotherapy: a new therapeutic approach for allograft rejection.

  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20020601

• Synthesis, photobiological activity and photoreactivity of methyl-thieno-8-azacoumarins, novel bioisosters of psoralen.

  Bioorganic & medicinal chemistry letters 20020506

• p53 and Fas ligand are required for psoralen and UVA-induced apoptosis in mouse epidermal cells.

  Cell death and differentiation 20020501

• Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020501

• Differential effect of 8-methoxypsoralen, 4,6,4'-trimethylangelicin, and chlorpromazine on cell death and TNF-alpha production.

  Archives of dermatological research 20020501

• 3-Alkyl- and 3-aryl-7H-furo[3,2-g]-1-benzopyran-7-ones: synthesis, photoreactivity, and fluorescence properties.

  Archiv der Pharmazie 20020501

• Studies on mechanism of 8-methoxypsoralen-DNA interaction in the dark.

  International journal of pharmaceutics 20020426

• Effects of storage conditions on furocoumarin levels in intact, chopped, or homogenized parsnips.

  Journal of agricultural and food chemistry 20020424

• Chalcones and other constituents of Dorstenia prorepens and Dorstenia zenkeri.

  Phytochemistry 20020401

• Amino acids in SRS1 and SRS6 are critical for furanocoumarin metabolism by CYP6B1v1, a cytochrome P450 monooxygenase.

  Insect molecular biology 20020401

• Simultaneous determination of furanocoumarins in infusions and decoctions from 'Carapiá' (dorstenia species) by high-performance liquid chromatography.

  Journal of agricultural and food chemistry 20020313

• Novel angular furo and thieno-quinolinones: synthesis and preliminary photobiological studies.

  Bioorganic & medicinal chemistry 20020301

• Bullous phytophotodermatitis associated with high natural concentrations of furanocoumarins in limes.

  American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20020301

• Decreased survival of UV-irradiated Staphylococcus aureus in the presence of 8-methoxypsoralen in the post-irradiation plating medium.

  Journal of photochemistry and photobiology. B, Biology 20020301

• Time course of 8-methoxypsoralen concentrations in skin and plasma after topical (bath and cream) and oral administration of 8-methoxypsoralen.

  Clinical pharmacology and therapeutics 20020301

• Synthesis and biological evaluation of a new furo[2,3-h]quinolin-2(1H)-one.

  Journal of medicinal chemistry 20020227

• Effects of the isoflavone 4',5,7-trihydroxyisoflavone (genistein) on psoralen plus ultraviolet A radiation (PUVA)-induced photodamage.

  Carcinogenesis 20020201

• Mitochondrial alterations in fanconi anemia fibroblasts following ultraviolet A or psoralen photoactivation.

  Photochemistry and photobiology 20020201

• [Acute generalized exanthematous pustulosis due to meladinine with positive patch tests].

  Annales de dermatologie et de venereologie 20020201

• Simple and rapid determination of psoralens in topic solutions using liquid chromatography.

  Journal of pharmaceutical and biomedical analysis 20020101

• Cell-impermeant pyridinium derivatives of psoralens as inhibitors of keratinocyte growth.

  Biochemical pharmacology 20020101

• Reliability of nested polymerase chain reaction in the diagnosis of bacterial endophthalmitis.

  American journal of ophthalmology 20020101

• Extracorporeal photopheresis in cutaneous T-cell lymphoma and graft-versus-host disease induces both immediate and progressive apoptotic processes.

  The British journal of dermatology 20020101

• Evaluation of synergism in the feeding deterrence of some furanocoumarins on Spodoptera littoralis.

  Journal of chemical ecology 20020101

• Characteristics of photopheresis treatments for the management of rejection in heart and lung transplant recipients.

  Journal of clinical apheresis 20020101

• Can the immersion time of PUVA bath therapy be shortened?

  Acta dermato-venereologica 20020101

• Oral administration of 5-methoxypsoralen affects the distribution and metabolism of 2-aminofluorene in Sprague-Dawley rats.

  In vivo (Athens, Greece) 20020101

• Epoxidation of some natural furocoumarins and furochromones using gamma-ray.

  Bollettino chimico farmaceutico 20020101

• Photoclastogenicity-an improved protocol, its validation, and investigation of the photogenotoxicity of DMBA.

  Environmental and molecular mutagenesis 20020101

• In vivo effect of 5- and 8-methoxypsoralens and cimetidine on R,S-warfarin metabolism in rat.

  Journal of applied toxicology : JAT 20020101

• The effect methoxsalene on hypnotic and subhypnotic doses of pentobarbital.

  European journal of drug metabolism and pharmacokinetics 20020101

• The effect of celery and parsley juices on pharmacodynamic activity of drugs involving cytochrome P450 in their metabolism.

  European journal of drug metabolism and pharmacokinetics 20020101

• Characterization of covalent adducts to intact cytochrome P450s by mass spectrometry.

  Methods in enzymology 20020101

• [The quantitative analysis of micronucleus induction in human lymphocytes cultured in vitro (preconditions for making modified micronucleus assay)].

  Radiatsionnaia biologiia, radioecologiia 20020101

• Psoralen and UVA light: an in vitro investigation of multiple immunological mechanisms underlying the immunosuppression induction in allograft rejection.

  Blood cells, molecules & diseases 20020101

• Methoxsalen with ultraviolet A therapy (PUVA).

  Report on carcinogens : carcinogen profiles 20020101

• S. cerevisiae has three pathways for DNA interstrand crosslink repair.

  Mutation research 20011219

• Systemic allergic contact dermatitis to 8-methoxypsoralen (8-MOP).

  Journal of the American Academy of Dermatology 20011201

• Photosensitization and mutation induced in Escherichia coli and Saccharomyces cerevisiae strains by dorstenin, a psoralen analog isolated from Dorstenia bahiensis.

  Planta medica 20011201

• Developmental variation in cytochrome P450 expression in Papilio polyxenes in response to xanthotoxin, a hostplant allelochemical.

  Archives of insect biochemistry and physiology 20011201

• Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists.

  American journal of physiology. Cell physiology 20011101

• PUVA downregulates whn expression in primary mouse keratinocytes.

  Journal of photochemistry and photobiology. B, Biology 20011101

• Anaphylaxis to 5-methoxypsoralen during photochemotherapy.

  The British journal of dermatology 20011101

• Indolopyridoquinazoline alkaloid from Leptothyrsa sprucei.

  Phytochemistry 20011001

• A bioassay using the human hepatoblastoma cell line HepG2 for detecting phototoxicity of furocoumarins.

  Planta medica 20011001

• [Treatment of plaque-type psoriasis with cream-PUVA therapy].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20011001

• Molecular analysis of multiple CYP6B genes from polyphagous Papilio species.

  Insect biochemistry and molecular biology 20010901

• Is the efficacy of psoralen plus ultraviolet A therapy for vitiligo enhanced by concurrent topical calcipotriol? A placebo-controlled double-blind study.

  The British journal of dermatology 20010901

• Effects of phytic acid and xanthotoxin on growth and detoxification in caterpillars.

  Journal of chemical ecology 20010901

• Inhibition of itch-scratch response by fruits of Cnidium monnieri in mice.

  Biological & pharmaceutical bulletin 20010901

• Formation of 6-formyl-7-hydroxy-8-methoxycoumarin and 5,8-dioxopsoralen by reaction of 8-methoxypsoralen with H2O2 and potassium superoxide (KO2) catalyzed by halogenated or perhalogenated 5,10,15,20-tetraarylporphyrinatoiron(III) chlorides.

  Chemical & pharmaceutical bulletin 20010901

• A study of the expression of the xenobiotic-metabolising cytochrome P450 proteins and of testosterone metabolism in bovine liver.

  Biochemical pharmacology 20010901

• Photoactivational cytokine-modulatory action of 8-methoxypsoralen plus ultraviolet A in lymphocytes, monocytes, and cutaneous T cell lymphoma cells.

  Annals of the New York Academy of Sciences 20010901

• Does the minimal phototoxic dose after 8-methoxypsoralen baths correlate with the individual's skin phototype?

  Photodermatology, photoimmunology & photomedicine 20010801

• Halothane-dependent lipid peroxidation in human liver microsomes is catalyzed by cytochrome P4502A6 (CYP2A6).

  Anesthesiology 20010801

• Plasma and skin concentration of 5-methoxypsoralen in psoriatic patients after oral administration.

  The Journal of investigative dermatology 20010801

• A comparison of the effect of narrow-band ultraviolet B in the treatment of psoriasis after salt-water baths and after 8-methoxypsoralen baths.

  The British journal of dermatology 20010801

• Acitretin therapy for palmoplantar pustulosis combined with UVA and topical 8-MOP.

  International journal of dermatology 20010801

• Furanochromone radical cations: generation, characterization and interaction with DNA.

  Biophysical chemistry 20010702

• Cyclooxygenase-2 expression and prostaglandin E2 biosynthesis are enhanced in scleroderma fibroblasts and inhibited by UVA irradiation.

  The Journal of rheumatology 20010701

• What's new in the treatment of vitiligo.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20010701

• Localized vitiligo successfully treated with cream-psoralen + ultraviolet A.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20010701

• Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific and selective CYP2A6 inhibitors in vitro.

  Drug metabolism and disposition: the biological fate of chemicals 20010601

• Extracorporeal photopheresis: a review.

  Blood reviews 20010601

• Liver cytochrome P450 CYP1A2 is markedly inhibited by systemic but not by bath PUVA in dermatological patients.

  The British journal of dermatology 20010601

• Laser resurfacing-induced hypopigmentation: histologic alterations and repigmentation with topical photochemotherapy.

  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20010601

• The risk of melanoma in association with long-term exposure to PUVA.

  Journal of the American Academy of Dermatology 20010501

• The effect of methoxsalen dose on ultraviolet-A-induced erythema.

  The Journal of investigative dermatology 20010501

• Kinetics and dose-response of photosensitivity in cream psoralen plus ultraviolet A photochemotherapy: comparative in vivo studies after topical application of three standard preparations.

  The British journal of dermatology 20010501

• Cream psoralen plus ultraviolet A therapy for granuloma annulare.

  The British journal of dermatology 20010501

• Coumarins isolated from Angelica gigas inhibit acetylcholinesterase: structure-activity relationships.

  Journal of natural products 20010501

• Evaluation of the immunomodulatory mechanisms of photochemotherapy in transplantation.

  Transplantation proceedings 20010501

• Expression of CYP6B1 and CYP6B3 cytochrome P450 monooxygenases and furanocoumarin metabolism in different tissues of Papilio polyxenes (Lepidoptera: Papilionidae).

  Insect biochemistry and molecular biology 20010427

• Correlation between 8-methoxypsoralen bath-water concentration and photosensitivity in bath-PUVA treatment.

  Journal of the American Academy of Dermatology 20010401

• The coumarin osthol attenuates the binding of thyrotropin-releasing hormone in rat pituitary GH4C1 cells.

  Planta medica 20010401

• Vasorelaxing effect of coumarins from Cnidium monnieri on rabbit corpus cavernosum.

  Planta medica 20010401

• Synthesis and properties of peptide nucleic acids containing a psoralen unit.

  Organic letters 20010322

• In vitro inhibition of cytochrome P450 enzymes in human liver microsomes by a potent CYP2A6 inhibitor, trans-2-phenylcyclopropylamine (tranylcypromine), and its nonamine analog, cyclopropylbenzene.

  Drug metabolism and disposition: the biological fate of chemicals 20010301

• Treatment of peripheral blood mononuclear cells with 8-methoxypsoralen plus ultraviolet A radiation induces a shift in cytokine expression from a Th1 to a Th2 response.

  The Journal of investigative dermatology 20010301

• Pharmacokinetic behaviour of sublingually administered 8-methoxypsoralen for PUVA therapy.

  Photodermatology, photoimmunology & photomedicine 20010201

• The PUVA-turban as a new option of applying a dilute psoralen solution selectively to the scalp of patients with alopecia areata.

  Journal of the American Academy of Dermatology 20010201

• Treatment of stage II cutaneous T-cell lymphoma with interferon alfa-2a and extracorporeal photochemotherapy: a prospective controlled trial.

  Journal of the American Academy of Dermatology 20010201

• Induction of unscheduled DNA synthesis in hairless mouse epidermis by 8-methoxypsoralen plus ultraviolet A (PUVA).

  The Journal of toxicological sciences 20010201

• Livedoid vasculitis responding to PUVA therapy.

  International journal of dermatology 20010201

• [Heracl'eum mantegazzi'anum: photosensitization].

  Praxis 20010118

• A method for the simultaneous evaluation of the activities of seven major human drug-metabolizing cytochrome P450s using an in vitro cocktail of probe substrates and fast gradient liquid chromatography tandem mass spectrometry.

  Drug metabolism and disposition: the biological fate of chemicals 20010101

• Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins.

  Clinical pharmacology and therapeutics 20010101

• Aquagenic pruritus responding to intermittent photochemotherapy.

  Clinical and experimental dermatology 20010101

• The psoralens adversely affect reproductive function in male wistar rats.

  Reproductive toxicology (Elmsford, N.Y.) 20010101

• Phototherapy of psoriasis: comparative experience of different phototherapeutic approaches.

  Dermatology (Basel, Switzerland) 20010101

• Immunomodulating effects of extracorporeal photochemotherapy in rat experimental allergic encephalomyelitis.

  International journal of tissue reactions 20010101

• Characterization of the mutational specificity of DNA cross-linking mutagens by the Lac+ reversion assay with Escherichia coli.

  Teratogenesis, carcinogenesis, and mutagenesis 20010101

• Penetration kinetics of 8-methoxypsoralen after 8-methoxypsoralen bath procedure with and without UVA irradiation.

  Skin pharmacology and applied skin physiology 20010101

• Furanocoumarins in celery and parsnips: method and multiyear Canadian survey.

  Journal of AOAC International 20010101

• Kinetics of phototoxicity in trioxysalen bath psoralen plus ultraviolet A photochemotherapy.

  Acta dermato-venereologica 20010101

• Induction of apoptosis, depletion of glutathione, and DNA damage by extracorporeal photochemotherapy and psoralen with exposure to UV light in vitro.

  Anticancer research 20010101

• Serum folate levels after UVA exposure: a two-group parallel randomised controlled trial.

  BMC dermatology 20010101

• Assessment of the phototoxic potential of compounds and finished topical products using a human reconstructed epidermis.

  In vitro & molecular toxicology 20010101

• Can a mixed damage interfere with DNA-protein cross-links repair?

  Journal of cellular and molecular medicine 20010101

• Metabolism of 3-methylindole by porcine liver microsomes: responsible cytochrome P450 enzymes.

  Toxicological sciences : an official journal of the Society of Toxicology 20000601

• Molecular cloning and expression of CYP6B8: a xanthotoxin-inducible cytochrome P450 cDNA from Helicoverpa zea.

  Insect biochemistry and molecular biology 20000101

• Human halothane metabolism, lipid peroxidation, and cytochromes P(450)2A6 and P(450)3A4.

  European journal of clinical pharmacology 20000101

• Mimicking gene defects to treat drug dependence.

  Annals of the New York Academy of Sciences 20000101

• Hepatitis from 5-methoxypsoralen occurring in a patient with previous flucloxacillin hepatitis.

  The Australasian journal of dermatology 19991101

• Carbaryl induces CYP1A1 gene expression in HepG2 and HaCaT cells but is not a ligand of the human hepatic Ah receptor.

  Toxicology and applied pharmacology 19970501

• Cytochrome P450 2E1 is the principal catalyst of human oxidative halothane metabolism in vitro.

  The Journal of pharmacology and experimental therapeutics 19970401

• Topical or oral administration with an extract of Polypodium leucotomos prevents acute sunburn and psoralen-induced phototoxic reactions as well as depletion of Langerhans cells in human skin.

  Photodermatology, photoimmunology & photomedicine 19970101

• Rectal suppositories of 8-methoxsalen produce fewer gastrointestinal side effects than the oral formulation.

  Journal of the American Academy of Dermatology 19960901

• Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes.

  Xenobiotica; the fate of foreign compounds in biological systems 19960701

• Antibacterial and antifungal polyine compounds from Glehnia littoralis ssp. leiocarpa.

  Planta medica 19960601

• Suppression of cytochrome P450 (Cyp1a-1) induction in mouse hepatoma Hepa-1C1C7 cells by methoxsalen.

  Biochemical and biophysical research communications 19950328

• Fulminant hepatic failure after methotrexate and PUVA therapy for psoriasis.

  Journal of clinical gastroenterology 19931201

• Photopheresis and human immunodeficiency virus (HIV) infection: the Annals views preliminary reports.

  Annals of internal medicine 19900815

• Nephrotoxicity of thiabendazole in mice depleted of glutathione by treatment with DL-buthionine sulphoximine.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19900301

• The drug methoxsalen, a suicide substrate for cytochrome P-450, decreases the metabolic activation, and prevents the hepatotoxicity, of carbon tetrachloride in mice.

  Biochemical pharmacology 19870315

• The effect of etretinate compared with different regimens of PUVA in the treatment of persistent palmoplantar pustulosis.

  The British journal of dermatology 19850401

• [Purpura caused by sensitization to 8-methoxypsoralen during PUVA-therapy].

  La Nouvelle presse medicale 19810207