301305-73-7 | 2-(3,4-Dimethoxyphenylcarbamoyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$13.00	$9.00
5mg	98%	in stock	$27.00	$19.00
10mg	98%	in stock	$41.00	$29.00

Description

• Catalog Number: AB79293
• Chemical Name: 2-(3,4-Dimethoxyphenylcarbamoyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
• CAS Number: 301305-73-7
• Molecular Formula: C18H20N2O4S
• Molecular Weight: 360.4274
• MDL Number: MFCD00617269
• SMILES: COc1cc(ccc1OC)C(=O)Nc1sc2c(c1C(=O)N)CCCC2

Computed Properties

• Complexity: 504
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 25
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 5
• XLogP3: 3.4

Literature

• A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.

  The Biochemical journal 20130415

• Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.

  Nature biotechnology 20111101

• Single agents with designed combination chemotherapy potential: synthesis and evaluation of substituted pyrimido[4,5-b]indoles as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents.

  Journal of medicinal chemistry 20100225

• Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3.

  Bioorganic & medicinal chemistry letters 20060615