3056-17-5 | Sanilvudine

Packsize	Purity	Availability	Price	Discounted Price
25mg	95%	in stock	$15.00	$10.00
250mg	95%	in stock	$16.00	$11.00
1g	95%	in stock	$25.00	$17.00
5g	95%	in stock	$39.00	$27.00
10g	95%	in stock	$65.00	$45.00
25g	95%	in stock	$136.00	$95.00
100g	95%	in stock	$355.00	$248.00
500g	95%	in stock	$1,069.00	$748.00

Description

• Catalog Number: AB40486
• Chemical Name: Sanilvudine
• CAS Number: 3056-17-5
• Molecular Formula: C10H12N2O4
• Molecular Weight: 224.2133
• MDL Number: MFCD00132921
• SMILES: Cc1cn([C@@H]2O[C@@H](C=C2)CO)c(=O)[nH]c1=O
• NSC Number: 759897

Computed Properties

• Complexity: 388
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: -0.8

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• Integration of population pharmacokinetics and pharmacogenetics: an aid to optimal nevirapine dose selection in HIV-infected individuals.

  The Journal of antimicrobial chemotherapy 20110601

• Disorders of fat partitioning in treated HIV-infection.

  Best practice & research. Clinical endocrinology & metabolism 20110601

• The effect of highly active antiretroviral therapy on the survival of HIV-infected children in a resource-deprived setting: a cohort study.

  PLoS medicine 20110601

• Major HIV resistance mutations in untreated Romanian patients.

  Journal of medicine and life 20110515

• Molecular recognition of the antiretroviral drug abacavir: towards the development of a novel carbazole-based fluorosensor.

  Journal of fluorescence 20110501

• From old to new nucleoside reverse transcriptase inhibitors: changes in body fat composition, metabolic parameters and mitochondrial toxicity after the switch from thymidine analogs to tenofovir or abacavir.

  Expert opinion on drug safety 20110501

• Metabolic benefits of switching to tenofovir/lamivudine after long-term use of stavudine/lamivudine in NNRTI-based antiretroviral regimens: a prospective study.

  The Journal of infection 20110501

• [Characteristics of antiretroviral drugs].

  Enfermedades infecciosas y microbiologia clinica 20110501

• Effectiveness of early antiretroviral therapy initiation to improve survival among HIV-infected adults with tuberculosis: a retrospective cohort study.

  PLoS medicine 20110501

• CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope.

  PLoS pathogens 20110501

• [Effects of daily administration of a stavudine/nelfinavir association on the fetuses and placentas of female albino rats].

  Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia 20110501

• Initiation of antiretroviral treatment in women after delivery can induce multiclass drug resistance in breastfeeding HIV-infected infants.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110415

• Design, characterization and in vitro evaluation of stavudine-loaded microspheres.

  Pharmaceutical development and technology 20110401

• Cohort profile: Hlabisa HIV treatment and care programme.

  International journal of epidemiology 20110401

• HIV neuropathy risk factors and symptom characterization in stavudine-exposed South Africans.

  Journal of pain and symptom management 20110401

• Relationship between neck circumference and cardiometabolic parameters in HIV-infected and non-HIV-infected adults.

  Diabetes care 20110401

• Synthesis and biological evaluation of fatty acyl ester derivatives of 2',3'-didehydro-2',3'-dideoxythymidine.

  Bioorganic & medicinal chemistry letters 20110401

• Lactic acidosis associated with severe neuromuscular weakness and stavudine therapy.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20110401

• Stavudine entrapped lipid nanoparticles for targeting lymphatic HIV reservoirs.

  Die Pharmazie 20110401

• Case of relapsed AIDS-related plasmablastic lymphoma treated with autologous stem cell transplantation and highly active antiretroviral therapy.

  Rare tumors 20110330

• The role of nucleoside and nucleotide analogues in nodular regenerative hyperplasia in HIV-infected patients: a case control study.

  Journal of hepatology 20110301

• Implementing a tenofovir-based first-line regimen in rural Lesotho: clinical outcomes and toxicities after two years.

  Journal of acquired immune deficiency syndromes (1999) 20110301

• HIV/HCV co-infection: pathogenesis, clinical complications, treatment, and new therapeutic technologies.

  Current HIV/AIDS reports 20110301

• Age-related skeletal muscle decline is similar in HIV-infected and uninfected individuals.

  The journals of gerontology. Series A, Biological sciences and medical sciences 20110301

• Type 2 diabetes and impaired glucose tolerance in two young adults infected with HIV early in life.

  Diabetes care 20110301

• Development and validation of a normal-phase HPTLC method for the simultaneous analysis of lamivudine, stavudine and nevirapine in fixed-dose combination tablets.

  Journal of pharmaceutical and biomedical analysis 20110220

• Marked reduction in prevalence of malaria parasitemia and anemia in HIV-infected pregnant women taking cotrimoxazole with or without sulfadoxine-pyrimethamine intermittent preventive therapy during pregnancy in Malawi.

  The Journal of infectious diseases 20110215

• Dyslipidemia among HIV-infected Patients with tuberculosis taking once-daily nonnucleoside reverse-transcriptase inhibitor-based antiretroviral therapy in India.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110215

• Intermuscular adipose tissue and metabolic associations in HIV infection.

  Obesity (Silver Spring, Md.) 20110201

• Tumour necrosis factor haplotypes associated with sensory neuropathy in Asian and Caucasian human immunodeficiency virus patients.

  Tissue antigens 20110201

• Standard measures are inadequate to monitor pediatric adherence in a resource-limited setting.

  AIDS and behavior 20110201

• Immunovirological outcomes and resistance patterns at 4 years of antiretroviral therapy use in HIV-infected patients in Cambodia.

  Tropical medicine & international health : TM & IH 20110201

• HIV-1 drug resistance testing from dried blood spots collected in rural Tanzania using the ViroSeq HIV-1 Genotyping System.

  The Journal of antimicrobial chemotherapy 20110201

• Approach to dyslipidemia, lipodystrophy, and cardiovascular risk in patients with HIV infection.

  Current atherosclerosis reports 20110201

• Additive effects of numbness and muscle aches on fatigue occurrence in individuals with HIV/AIDS who are taking antiretroviral therapy.

  Journal of pain and symptom management 20110201

• Diastereoselective synthesis of cyclosaligenyl-nucleosyl-phosphotriesters.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110201

• Recent FDA approvals and changes.

  AIDS patient care and STDs 20110201

• Episomal viral cDNAs identify a reservoir that fuels viral rebound after treatment interruption and that contributes to treatment failure.

  PLoS pathogens 20110201

• Nevirapine induced Stevens-Johnson syndrome in an HIV infected patient.

  Indian journal of pharmacology 20110201

• [Mass screening for hypothyroidism in a cohort of HIV infected patients in a Bogotá hospital, Colombia].

  Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia 20110201

• Impact of NRTIs on lipid levels among a large HIV-infected cohort initiating antiretroviral therapy in clinical care.

  AIDS (London, England) 20110114

• European mitochondrial DNA haplogroups and metabolic changes during antiretroviral therapy in AIDS Clinical Trials Group Study A5142.

  AIDS (London, England) 20110102

• Lipoatrophy of the footpad in HIV-treated patients is associated with increased PAI-1.

  Biological research for nursing 20110101

• Risk factors for advanced liver fibrosis in HIV-infected individuals: role of antiretroviral drugs and insulin resistance.

  Journal of viral hepatitis 20110101

• Impact of antiretroviral treatment on (13) C-methionine metabolism as a marker of hepatic mitochondrial function: a longitudinal study.

  HIV medicine 20110101

• Stavudine toxicity in women is the main reason for treatment change in a 3-year prospective cohort of adult patients started on first-line antiretroviral treatment in Uganda.

  Journal of acquired immune deficiency syndromes (1999) 20110101

• Effect of nucleoside and nucleotide analog reverse transcriptase inhibitors on cell-mediated immune functions.

  AIDS research and human retroviruses 20110101

• Functional characterization of the promoter of the human Lon protease gene.

  Mitochondrion 20110101

• [Rate of genotypic mutations and resistance to antiretroviral drugs in a general hospital].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20110101

• Understanding diabetes in patients with HIV/AIDS.

  Diabetology & metabolic syndrome 20110101

• Synthesis and an antiviral activity evaluation of nucleoside 5´-O-(N-acyl) phosphoramidates.

  Antiviral chemistry & chemotherapy 20110101

• Timing of antiretroviral therapy for HIV in the setting of TB treatment.

  Clinical & developmental immunology 20110101

• Expenditures for the care of HIV-infected patients in rural areas in China's antiretroviral therapy programs.

  BMC medicine 20110101

• K70Q adds high-level tenofovir resistance to 'Q151M complex' HIV reverse transcriptase through the enhanced discrimination mechanism.

  PloS one 20110101

• Quality of data collection in a large HIV observational clinic database in sub-Saharan Africa: implications for clinical research and audit of care.

  Journal of the International AIDS Society 20110101

• Culture conversion among HIV co-infected multidrug-resistant tuberculosis patients in Tugela Ferry, South Africa.

  PloS one 20110101

• Clinical monitoring and correlates of nephropathy in SIV-infected macaques during high-dose antiretroviral therapy.

  AIDS research and therapy 20110101

• Adherence and virologic suppression during the first 24 weeks on antiretroviral therapy among women in Johannesburg, South Africa - a prospective cohort study.

  BMC public health 20110101

• A biregional survey and review of first-line treatment failure and second-line paediatric antiretroviral access and use in Asia and southern Africa.

  Journal of the International AIDS Society 20110101

• Multi-nucleoside reverse transcriptase inhibitor resistant HIV type-1 in a patient from Sierra Leone failing stavudine, lamivudine and nevirapine.

  Antiviral therapy 20110101

• Antiretroviral therapy-associated acute motor and sensory axonal neuropathy.

  Case reports in neurology 20110101

• Development of Buffalo Hump in the course of antiretroviral therapy including raltegravir and unboosted atazanavir: a case report and review of the literature.

  Journal of medical case reports 20110101

• Management of HIV-1 associated hepatitis in patients with acquired immunodeficiency syndrome: role of a successful control of viral replication.

  AIDS research and therapy 20110101

• Weight and height z-scores improve after initiating ART among HIV-infected children in rural Zambia: a cohort study.

  BMC infectious diseases 20110101

• Timely HAART initiation may pave the way for a better viral control.

  BMC infectious diseases 20110101

• Neurobehavioral effects in HIV-positive individuals receiving highly active antiretroviral therapy (HAART) in Gaborone, Botswana.

  PloS one 20110101

• Prevalence of potential drug-drug interactions involving antiretroviral drugs in a large Kenyan cohort.

  PloS one 20110101

• Correcting for mortality among patients lost to follow up on antiretroviral therapy in South Africa: a cohort analysis.

  PloS one 20110101

• Enhanced uridine bioavailability following administration of a triacetyluridine-rich nutritional supplement.

  PloS one 20110101

• Antiretroviral therapy outcomes in HIV-infected children after adjusting protease inhibitor dosing during tuberculosis treatment.

  PloS one 20110101

• Incidence and predictors of immune reconstitution inflammatory syndrome in a rural area of Mozambique.

  PloS one 20110101

• Drug efficacy by direct and adjusted indirect comparison to placebo: An illustration by Mycobacterium avium complex prophylaxis in HIV.

  AIDS research and therapy 20110101

• 'Dynamic range' of inferred phenotypic HIV drug resistance values in clinical practice.

  PloS one 20110101

• Diabetes mellitus, insulin resistance, and metabolic syndrome in HIV-positive patients in South India.

  International journal of general medicine 20110101

• Renal safety of a tenofovir-containing first line regimen: experience from an antiretroviral cohort in rural Lesotho.

  PloS one 20110101

• Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease.

  Retrovirology 20110101

• Highly active antiretroviral therapy: Does it Sound toxic?

  Journal of pharmacy & bioallied sciences 20110101

• High efficacy of lopinavir/r-based second-line antiretroviral treatment after 24 months of follow up at ESTHER/Calmette Hospital in Phnom Penh, Cambodia.

  Journal of the International AIDS Society 20110101

• Driving a decade of change: HIV/AIDS, patents and access to medicines for all.

  Journal of the International AIDS Society 20110101

• Machine learning on normalized protein sequences.

  BMC research notes 20110101

• Resveratrol attenuates azidothymidine-induced cardiotoxicity by decreasing mitochondrial reactive oxygen species generation in human cardiomyocytes.

  Molecular medicine reports 20110101

• Changes in lipid profiles after switching to a protease inhibitor-containing cART--unfavourable effect of fosamprenavir in obese patients.

  European journal of medical research 20110101

• Cost effectiveness of a pharmacy-only refill program in a large urban HIV/AIDS clinic in Uganda.

  PloS one 20110101

• Nutrition and inflammation serum biomarkers are associated with 12-week mortality among malnourished adults initiating antiretroviral therapy in Zambia.

  Journal of the International AIDS Society 20110101

• Four-year treatment outcomes of adult patients enrolled in Mozambique's rapidly expanding antiretroviral therapy program.

  PloS one 20110101

• Tinea incognito Caused by Microsporum gypseum in a Patient with Advanced HIV Infection: A Case Report.

  Case reports in dermatology 20110101

• HIV Suppression among Patients on Treatment in Vietnam: A Review of HIV Viral Load Testing in a Public Urban Clinic in Ho Chi Minh City.

  AIDS research and treatment 20110101

• Long-Term Outcome of an HIV-Treatment Programme in Rural Africa: Viral Suppression despite Early Mortality.

  AIDS research and treatment 20110101

• Utilization patterns and projected demand of antiretroviral drugs in low- and middle-income countries.

  AIDS research and treatment 20110101

• A risk-factor guided approach to reducing lactic acidosis and hyperlactatemia in patients on antiretroviral therapy.

  PloS one 20110101

• Improved antiretroviral treatment outcome in a rural African setting is associated with cART initiation at higher CD4 cell counts and better general health condition.

  BMC infectious diseases 20110101

• Identification of new, emerging HIV-1 unique recombinant forms and drug resistant viruses circulating in Cameroon.

  Virology journal 20110101

• Prevalence of and risk factors for lipodystrophy among HIV-infected patients receiving combined antiretroviral treatment in the Asia-Pacific region: results from the TREAT Asia HIV Observational Database (TAHOD).

  Endocrine journal 20110101

• Long-term renal safety of tenofovir disoproxil fumarate in vertically HIV-infected children, adolescents and young adults: a 60-month follow-up study.

  Clinical drug investigation 20110101

• Excellent adherence to antiretrovirals in HIV+ Zambian children is compromised by disrupted routine, HIV nondisclosure, and paradoxical income effects.

  PloS one 20110101

• HIV-Associated Tuberculosis in the Newborn and Young Infant.

  International journal of pediatrics 20110101

• Evaluation of WHO Criteria for Viral Failure in Patients on Antiretroviral Treatment in Resource-Limited Settings.

  AIDS research and treatment 20110101

• HIV-infected children in rural Zambia achieve good immunologic and virologic outcomes two years after initiating antiretroviral therapy.

  PloS one 20110101

• Factors influencing retention in care after starting antiretroviral therapy in a rural South African programme.

  PloS one 20110101

• UMP/CMPK is not the critical enzyme in the metabolism of pyrimidine ribonucleotide and activation of deoxycytidine analogs in human RKO cells.

  PloS one 20110101

• Survival of HIV-infected adolescents on antiretroviral therapy in Uganda: findings from a nationally representative cohort in Uganda.

  PloS one 20110101

• The feasibility of automating audit and feedback for ART guideline adherence in Malawi.

  Journal of the American Medical Informatics Association : JAMIA 20110101

• The evolution of HIV-1 reverse transcriptase in route to acquisition of Q151M multi-drug resistance is complex and involves mutations in multiple domains.

  Retrovirology 20110101

• The net cost of incorporating resistance testing into HIV/AIDS treatment in South Africa: a Markov model with primary data.

  Journal of the International AIDS Society 20110101

• Barriers to initiation of antiretrovirals during antituberculosis therapy in Africa.

  PloS one 20110101

• Added value of deep sequencing relative to population sequencing in heavily pre-treated HIV-1-infected subjects.

  PloS one 20110101

• Safety and tolerability of antiretrovirals during pregnancy.

  Infectious diseases in obstetrics and gynecology 20110101

• Incidence and risk factors of serious adverse events during antituberculous treatment in Rwanda: a prospective cohort study.

  PloS one 20110101

• Presentation and outcome of tuberculous meningitis in a high HIV prevalence setting.

  PloS one 20110101

• Contraception in HIV-positive female adolescents.

  AIDS research and therapy 20110101

• A Multicenter, Open Labeled, Randomized, Phase III Study Comparing Lopinavir/Ritonavir Plus Atazanavir to Lopinavir/Ritonavir Plus Zidovudine and Lamivudine in Naive HIV-1-Infected Patients: 48-Week Analysis of the LORAN Trial.

  The open AIDS journal 20110101

• HIV and HAART-Associated Dyslipidemia.

  The open cardiovascular medicine journal 20110101

• Antiretroviral medications disrupt microglial phagocytosis of β-amyloid and increase its production by neurons: implications for HIV-associated neurocognitive disorders.

  Molecular brain 20110101

• WHO 2010 guidelines for prevention of mother-to-child HIV transmission in Zimbabwe: modeling clinical outcomes in infants and mothers.

  PloS one 20110101

• Decreased heart rate variability in HIV positive patients receiving antiretroviral therapy: importance of blood glucose and cholesterol.

  PloS one 20110101

• A template-dependent dislocation mechanism potentiates K65R reverse transcriptase mutation development in subtype C variants of HIV-1.

  PloS one 20110101

• Cost of surgical intervention for reconstructive therapy of HIV-associated facial lipoatrophy.

  Patient preference and adherence 20110101

• Orange juice and its component, hesperidin, decrease the expression of multidrug resistance-associated protein 2 in rat small intestine and liver.

  Journal of biomedicine & biotechnology 20110101

• High prevalence of HIV-1 drug resistance among patients on first-line antiretroviral treatment in Lomé, Togo.

  Journal of the International AIDS Society 20110101

• Retention in an antiretroviral therapy programme during an era of decreasing drug cost in Limbe, Cameroon.

  Journal of the International AIDS Society 20110101

• Lactic acidosis and symptomatic hyperlactataemia in a randomized trial of first-line therapy in HIV-infected adults in South Africa.

  Antiviral therapy 20110101

• Immune reconstitution and inflammatory syndrome due to disseminated tuberculosis in a case of human immunodeficiency virus 2 infection.

  Indian journal of pharmacology 20110101

• Tenofovir nephrotoxicity: 2011 update.

  AIDS research and treatment 20110101

• Virological breakthrough: a risk factor for loss to followup in a large community-based cohort on antiretroviral therapy.

  AIDS research and treatment 20110101

• Identification of amino acid phosphorodiamidates of antiviral nucleosides using electrospray ionization tandem mass spectrometry.

  European journal of mass spectrometry (Chichester, England) 20110101

• Efficacy of intravenous amphotericin B-polybutylcyanoacrylate nanoparticles against cryptococcal meningitis in mice.

  International journal of nanomedicine 20110101

• Is a HIV vaccine a viable option and at what price? An economic evaluation of adding HIV vaccination into existing prevention programs in Thailand.

  BMC public health 20110101

• Oral lesions associated with nevirapine-related Stevens Johnson syndrome: A report of four cases.

  Journal of oral and maxillofacial pathology : JOMFP 20110101

• Tuberculosis: current situation, challenges and overview of its control programs in India.

  Journal of global infectious diseases 20110101

• Long-term costs and health impact of continued global fund support for antiretroviral therapy.

  PloS one 20110101

• Randomized trial of time-limited interruptions of protease inhibitor-based antiretroviral therapy (ART) vs. continuous therapy for HIV-1 infection.

  PloS one 20110101

• Minor HIV-1 variants with the K103N resistance mutation during intermittent efavirenz-containing antiretroviral therapy and virological failure.

  PloS one 20110101

• Time to and Predictors of CD4+ T-Lymphocytes Recovery in HIV-Infected Children Initiating Highly Active Antiretroviral Therapy in Ghana.

  AIDS research and treatment 20110101

• Antiretroviral treatment reverses HIV-associated anemia in rural Tanzania.

  BMC infectious diseases 20110101

• Association of age with mortality and virological and immunological response to antiretroviral therapy in rural South African adults.

  PloS one 20110101

• Non-cirrhotic portal hypertension in human immunodeficiency virus-infected patients: a new challenge in antiretroviral therapy era.

  The open AIDS journal 20110101

• Does HAART efficacy translate to effectiveness? Evidence for a trial effect.

  PloS one 20110101

• HLA involvement in nevirapine-induced dermatological reaction in antiretroviral-treated HIV-1 patients.

  Journal of pharmacology & pharmacotherapeutics 20110101

• Recurrent Meningitis and Subarachnoid Hemorrhage Due to Salmonella in an HIV+ Patient: Case Report and Mini-Review of the Literature.

  The open AIDS journal 20110101

• Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam.

  AIDS research and treatment 20110101

• Immunovirological response to combined antiretroviral therapy and drug resistance patterns in children: 1- and 2-year outcomes in rural Uganda.

  BMC pediatrics 20110101

• An overview of post exposure prophylaxis for HIV in health care personals: Gujarat scenario.

  Indian journal of sexually transmitted diseases and AIDS 20110101

• Two years CD4 count follow-up of rural patients on antiretroviral therapy: A study in Government Hospital.

  Indian journal of sexually transmitted diseases and AIDS 20110101

• Impact of small body weight on tenofovir-associated renal dysfunction in HIV-infected patients: a retrospective cohort study of Japanese patients.

  PloS one 20110101

• Alternative antiretroviral monitoring strategies for HIV-infected patients in east Africa: opportunities to save more lives?

  Journal of the International AIDS Society 20110101

• Graves' Disease as a Manifestation of Immune Reconstitution in HIV-Infected Individuals after Initiation of Highly Active Antiretroviral Therapy.

  AIDS research and treatment 20110101

• Effectiveness of protease inhibitor monotherapy versus combination antiretroviral maintenance therapy: a meta-analysis.

  PloS one 20110101

• Long-term outcomes of liver transplant patients with human immunodeficiency virus infection and end-stage-liver-disease: single center experience.

  European journal of medical research 20110101

• Dyslipidaemia in HIV-infected women on antiretroviral therapy. Analysis of 922 patients from the Spanish VACH cohort.

  BMC women's health 20110101

• Anemia and iron homeostasis in a cohort of HIV-infected patients in Indonesia.

  BMC infectious diseases 20110101

• Risk factors associated with increased mortality among HIV infected children initiating antiretroviral therapy (ART) in South Africa.

  PloS one 20110101

• Pregnancy and virologic response to antiretroviral therapy in South Africa.

  PloS one 20110101

• Birth outcomes in South African women receiving highly active antiretroviral therapy: a retrospective observational study.

  Journal of the International AIDS Society 20110101

• Treatment simplification in HIV-infected adults as a strategy to prevent toxicity, improve adherence, quality of life and decrease healthcare costs.

  Patient preference and adherence 20110101

• Treatment interruption and variation in tablet taking behaviour result in viral failure: a case-control study from Cape Town, South Africa.

  PloS one 20110101

• Nephrotoxicity of HAART.

  AIDS research and treatment 20110101

• HIV drug resistance (HIVDR) in antiretroviral therapy-naïve patients in Tanzania not eligible for WHO threshold HIVDR survey is dramatically high.

  PloS one 20110101

• Pilot, randomized study assessing safety, tolerability and efficacy of simplified LPV/r maintenance therapy in HIV patients on the 1 PI-based regimen.

  PloS one 20110101

• Author's reply.

  Journal of neurosciences in rural practice 20110101

• Bone mineral density in HIV-negative men participating in a tenofovir pre-exposure prophylaxis randomized clinical trial in San Francisco.

  PloS one 20110101

• Long-term virological, immunological and mortality outcomes in a cohort of HIV-infected female sex workers treated with highly active antiretroviral therapy in Africa.

  BMC public health 20110101

• A longitudinal study of stavudine-associated toxicities in a large cohort of South African HIV infected subjects.

  BMC infectious diseases 20110101

• Lyme neuroborreliosis in HIV-1 positive men successfully treated with oral doxycycline: a case series and literature review.

  Journal of medical case reports 20110101

• Antiretroviral treatment-induced dyslipidemia in HIV-infected patients is influenced by the APOC3-related rs10892151 polymorphism.

  BMC medical genetics 20110101

• First-line antiretroviral therapy and dyslipidemia in people living with HIV-1 in Cameroon: a cross-sectional study.

  AIDS research and therapy 20110101

• Trends in the clinical characteristics of HIV-infected patients initiating antiretroviral therapy in Kenya, Uganda and Tanzania between 2002 and 2009.

  Journal of the International AIDS Society 20110101

• The first decade of antiretroviral therapy in Africa.

  Globalization and health 20110101

• Antiretroviral drug supply challenges in the era of scaling up ART in Malawi.

  Journal of the International AIDS Society 20110101

• Enrollment characteristics and risk behaviors of injection drug users participating in the Bangkok Tenofovir Study, Thailand.

  PloS one 20110101

• HIV as a chronic disease considerations for service planning in resource-poor settings.

  Globalization and health 20110101

• Promoting male involvement to improve PMTCT uptake and reduce antenatal HIV infection: a cluster randomized controlled trial protocol.

  BMC public health 20110101

• A win-win solution?: A critical analysis of tiered pricing to improve access to medicines in developing countries.

  Globalization and health 20110101

• Treatment of hepatitis B in decompensated liver cirrhosis.

  International journal of hepatology 20110101

• Reverse transcriptase drug resistance mutations in HIV-1 subtype C infected patients on ART in Karonga District, Malawi.

  AIDS research and therapy 20110101

• Economic returns to investment in AIDS treatment in low and middle income countries.

  PloS one 20110101

• High rates of adherence and treatment success in a public and public-private HIV clinic in India: potential benefits of standardized national care delivery systems.

  BMC health services research 20110101

• HAART induced adverse drug reactions: a retrospective analysis at a tertiary referral health care center in India.

  The International journal of risk & safety in medicine 20110101

• Evaluation of incidence of zidovudine induced anemia in Indian human immunodeficiency virus positive patients in comparison with stavudine based highly active antiretroviral therapy.

  The International journal of risk & safety in medicine 20110101

• Immunological failure despite virological suppression in HIV seropositive individuals on antiretroviral therapy.

  Indian journal of sexually transmitted diseases and AIDS 20110101

• Etravirine and rilpivirine resistance in HIV-1 subtype CRF01_AE-infected adults failing non-nucleoside reverse transcriptase inhibitor-based regimens.

  Antiviral therapy 20110101

• Bioequivalence of dispersed stavudine: opened versus closed capsule dosing.

  Antiviral therapy 20110101

• Immunologic and virologic failure after first-line NNRTI-based antiretroviral therapy in Thai HIV-infected children.

  AIDS research and therapy 20110101

• South Asian Consensus Guidelines for the rational management of diabetes in human immunodeficiency virus/acquired immunodeficiency syndrome.

  Indian journal of endocrinology and metabolism 20110101

• Human immunodeficiency virus endocrinopathy.

  Indian journal of endocrinology and metabolism 20110101

• Anti-retroviral treatment outcomes among older adults in Zomba district, Malawi.

  PloS one 20110101

• Increase of transmitted drug resistance among HIV-infected sub-Saharan Africans residing in Spain in contrast to the native population.

  PloS one 20110101

• Predictors of limb fat gain in HIV positive patients following a change to tenofovir-emtricitabine or abacavir-lamivudine.

  PloS one 20110101

• A prospective study of vaginal trichomoniasis and HIV-1 shedding in women on antiretroviral therapy.

  BMC infectious diseases 20110101

• The antiretroviral efficacy of highly active antiretroviral therapy and plasma nevirapine concentrations in HIV-TB co-infected Indian patients receiving rifampicin based antituberculosis treatment.

  AIDS research and therapy 20110101

• Male gender predicts mortality in a large cohort of patients receiving antiretroviral therapy in Uganda.

  Journal of the International AIDS Society 20110101

• Complete Healing of a Giant Wart in a Severely Immune-Compromised Patient with HIV Infection Treated with Acupuncture.

  Case reports in dermatology 20110101

• Incidence and risk factors of antiretroviral treatment failure in treatment-naïve HIV-infected patients at Chiang Mai University Hospital, Thailand.

  AIDS research and therapy 20110101

• Nevirapine plasma concentrations are associated with virologic response and hepatotoxicity in Chinese patients with HIV infection.

  PloS one 20110101

• Utility of routine viral load, CD4 cell count, and clinical monitoring among adults with HIV receiving antiretroviral therapy in Uganda: randomised trial.

  BMJ (Clinical research ed.) 20110101

• CD4 cell count and viral load monitoring in patients undergoing antiretroviral therapy in Uganda: cost effectiveness study.

  BMJ (Clinical research ed.) 20110101

• Effect of anemia on hepatotoxicity of HAART in HIV patients in Benin city.

  Nigerian medical journal : journal of the Nigeria Medical Association 20110101

• It is time to consider third-line options in antiretroviral-experienced paediatric patients?

  Journal of the International AIDS Society 20110101

• Undernutrition among HIV-positive children in Dar es Salaam, Tanzania: antiretroviral therapy alone is not enough.

  BMC public health 20110101

• Prevalence and predictors of kaposi sarcoma herpes virus seropositivity: a cross-sectional analysis of HIV-infected adults initiating ART in Johannesburg, South Africa.

  Infectious agents and cancer 20110101

• Intimate partner violence among women with HIV infection in rural Uganda: critical implications for policy and practice.

  BMC women's health 20110101

• Impact of comorbidities and drug therapy on development of renal impairment in a predominantly African American and Hispanic HIV clinic population.

  HIV/AIDS (Auckland, N.Z.) 20110101

• Antiretroviral therapy initiated soon after HIV diagnosis as standard care: potential to save lives?

  HIV/AIDS (Auckland, N.Z.) 20110101

• Characteristics of foot fractures in HIV-infected patients previously treated with tenofovir versus non-tenofovir-containing highly active antiretroviral therapy.

  HIV/AIDS (Auckland, N.Z.) 20110101

• Growth hormone and tesamorelin in the management of HIV-associated lipodystrophy.

  HIV/AIDS (Auckland, N.Z.) 20110101

• National prevalence and trends of HIV transmitted drug resistance in Mexico.

  PloS one 20110101

• Adherence to highly active antiretroviral treatment in HIV-infected Rwandan women.

  PloS one 20110101

• Resistance patterns selected by nevirapine vs. efavirenz in HIV-infected patients failing first-line antiretroviral treatment: a bayesian analysis.

  PloS one 20110101

• Toxicity associated with stavudine dose reduction from 40 to 30 mg in first-line antiretroviral therapy.

  PloS one 20110101

• [Energetic, conformational and electron density topological properties of 2',3'-didehydro-2',3'-dideoxythymidine: a quantum chemical study].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101

• Correlation between lamivudine plasma concentrations and patient self-reported adherence to antiretroviral treatment in experienced HIV patients.

  Therapeutics and clinical risk management 20110101

• Cost-effectiveness analysis of initial HIV treatment under Italian guidelines.

  ClinicoEconomics and outcomes research : CEOR 20110101

• Comparing antiretroviral treatment outcomes between a prospective community-based and hospital-based cohort of HIV patients in rural Uganda.

  BMC international health and human rights 20110101

• Transferosomes - A vesicular transdermal delivery system for enhanced drug permeation.

  Journal of advanced pharmaceutical technology & research 20110101

• Emergence of HBV resistance to lamivudine (3TC) in HIV/HBV co-infected patients in The Gambia, West Africa.

  BMC research notes 20110101

• Estimating loss to follow-up in HIV-infected patients on antiretroviral therapy: the effect of the competing risk of death in Zambia and Switzerland.

  PloS one 20110101

• Early mortality in adults initiating antiretroviral therapy (ART) in low- and middle-income countries (LMIC): a systematic review and meta-analysis.

  PloS one 20110101

• Twice-daily versus once-daily antiretroviral therapy and coformulation strategies in HIV-infected adults: benefits, risks, or burden?

  Patient preference and adherence 20110101

• Lipodystrophy in HIV patients: its challenges and management approaches.

  HIV/AIDS (Auckland, N.Z.) 20110101

• Formulation and optimization of sustained release Stavudine microspheres using response surface methodology.

  ISRN pharmaceutics 20110101

• Severe enophthalmos and lagophthalmos secondary to HIV-associated lipoatrophy.

  BMJ case reports 20110101

• Effect of stavudine-based antiretroviral therapy on the severity of polyneuropathy in HIV/AIDS patients: a preliminary report from Zaria, Northern Nigeria.

  West African journal of medicine 20110101

• Ionotropically Gelled Novel Hydrogel Beads: Preparation, Characterization and In vitro Evaluation.

  Indian journal of pharmaceutical sciences 20110101

• Evaluating patients for second-line antiretroviral therapy in India: the role of targeted viral load testing.

  Journal of acquired immune deficiency syndromes (1999) 20101215

• A predictive ligand-based Bayesian model for human drug-induced liver injury.

  Drug metabolism and disposition: the biological fate of chemicals 20101201

• Weight loss after the first year of stavudine-containing antiretroviral therapy and its association with lipoatrophy, virological failure, adherence and CD4 counts at primary health care level in Kigali, Rwanda.

  Transactions of the Royal Society of Tropical Medicine and Hygiene 20101201

• Changing baseline characteristics among patients in the China National Free Antiretroviral Treatment Program, 2002-09.

  International journal of epidemiology 20101201

• Scaling up the 2010 World Health Organization HIV Treatment Guidelines in resource-limited settings: a model-based analysis.

  PLoS medicine 20101201

• Comparison of the Mechanisms of Drug Resistance among HIV, Hepatitis B, and Hepatitis C.

  Viruses 20101201

• Characteristics, immunological response & treatment outcomes of HIV-2 compared with HIV-1 & dual infections (HIV 1/2) in Mumbai.

  The Indian journal of medical research 20101201

• Epidemiology of hepatitis C virus infection & liver disease among injection drug users (IDUs) in Chennai, India.

  The Indian journal of medical research 20101201

• Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after cryptococcal meningitis: a prospective cohort study.

  PLoS medicine 20101201

• Adverse effects after HAART Initiation in resource-limited settings: a prospective study from Mysore, India.

  Journal of infection in developing countries 20101124

• Antiretroviral adherence and development of drug resistance are the strongest predictors of genital HIV-1 shedding among women initiating treatment.

  The Journal of infectious diseases 20101115

• A randomized factorial trial comparing 4 treatment regimens in treatment-naive HIV-infected persons with AIDS and/or a CD4 cell count <200 cells/μL in South Africa.

  The Journal of infectious diseases 20101115

• Diastereoselective synthesis of aryloxy phosphoramidate prodrugs of 3'-deoxy-2',3'-didehydrothymidine monophosphate.

  Journal of medicinal chemistry 20101111

• Progressive mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs).

  Toxicological sciences : an official journal of the Society of Toxicology 20101101

• Strategies for nevirapine initiation in HIV-infected children taking pediatric fixed-dose combination 'baby pills' in Zambia: a randomized controlled trial.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20101101

• Role of HIV Subtype Diversity in the Development of Resistance to Antiviral Drugs.

  Viruses 20101101

• The MMP1 (-16071G/2G) single nucleotide polymorphism associates with the HAART-related lipodystrophic syndrome.

  AIDS (London, England) 20101023

• Synthesis and anti-HIV-1 evaluation of phosphonates which mimic the 5'-monophosphate of 4'-branched 2',3'-didehydro-2',3'-dideoxy nucleosides.

  Bioorganic & medicinal chemistry 20101015

• A chewable pediatric fixed-dose combination tablet of stavudine, lamivudine, and nevirapine: pharmacokinetics and safety compared with the individual liquid formulations in human immunodeficiency virus-infected children in Thailand.

  The Pediatric infectious disease journal 20101001

• Association between systemic inflammation and incident diabetes in HIV-infected patients after initiation of antiretroviral therapy.

  Diabetes care 20101001

• Association between abacavir exposure and increased risk for cardiovascular disease in patients with human immunodeficiency virus.

  Pharmacotherapy 20101001

• Incidence of atazanavir-associated hyperbilirubinemia in Korean HIV patients: 30 months follow-up results in a population with low UDP-glucuronosyltransferase1A1*28 allele frequency.

  Journal of Korean medical science 20101001

• Recent FDA approvals and changes.

  AIDS patient care and STDs 20101001

• Comparison of HPLC & spectrophotometric methods for estimation of antiretroviral drug content in pharmaceutical products.

  The Indian journal of medical research 20101001

• Reuse of nevirapine in exposed HIV-infected children after protease inhibitor-based viral suppression: a randomized controlled trial.

  JAMA 20100908

• Simultaneous determination of lamivudine, stavudine and nevirapine in human plasma by LC-MS/MS and its application to pharmacokinetic study in clinic.

  Biomedical chromatography : BMC 20100901

• Abdominal tuberculosis: sonographic diagnosis and treatment response in HIV-positive adults in rural South Africa.

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20100901

• The genetic toxicity effects of lamivudine and stavudine antiretroviral agents.

  Expert opinion on drug safety 20100901

• Drug resistance is widespread among children who receive long-term antiretroviral treatment at a rural Tanzanian hospital.

  The Journal of antimicrobial chemotherapy 20100901

• Human immunodeficiency virus treatment-induced adipose tissue pathology and lipoatrophy: prevalence and metabolic consequences.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100901

• Short communication: Severe symptomatic hyperlactatemia among HIV type 1-infected adults on antiretroviral therapy in Côte d'Ivoire.

  AIDS research and human retroviruses 20100901

• Genotypic and phenotypic cross-drug resistance of harboring drug-resistant HIV type 1 subtype B' strains from former blood donors in central Chinese provinces.

  AIDS research and human retroviruses 20100901

• Implementation of a validated peripheral neuropathy screening tool in patients receiving antiretroviral therapy in Mombasa, Kenya.

  The American journal of tropical medicine and hygiene 20100901

• Recent FDA approvals and changes.

  AIDS patient care and STDs 20100901

• Synthesis and transdermal penetration of stavudine-5'-esters.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20100901

• Aryl phosphoramidates of 5-phospho erythronohydroxamic acid, a new class of potent trypanocidal compounds.

  Journal of medicinal chemistry 20100826

• Stavudine or zidovudine in three-drug combination therapy for initial treatment of HIV infection in antiretroviral-naïve individuals.

  The Cochrane database of systematic reviews 20100804

• Drug resistance in human immunodeficiency virus type-1 infected Zambian children using adult fixed dose combination stavudine, lamivudine, and nevirapine.

  The Pediatric infectious disease journal 20100801

• Methadone, buprenorphine, and street drug interactions with antiretroviral medications.

  Current HIV/AIDS reports 20100801

• Mitochondrial dysfunction in CD4+ lymphocytes from stavudine-treated HIV patients.

  Mitochondrion 20100801

• Using touchscreen electronic medical record systems to support and monitor national scale-up of antiretroviral therapy in Malawi.

  PLoS medicine 20100801

• Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report.

  Viruses 20100801

• Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity.

  Toxins 20100801

• Regional adipose tissue measured by MRI over 5 years in HIV-infected and control participants indicates persistence of HIV-associated lipoatrophy.

  AIDS (London, England) 20100717

• Possible mitochondrial dysfunction and its association with antiretroviral therapy use in children perinatally infected with HIV.

  The Journal of infectious diseases 20100715

• Drug-resistant mutation patterns in CRF01_AE cases that failed d4T+3TC+nevirapine fixed-dosed, combination treatment: Follow-up study from the Lampang cohort.

  Antiviral research 20100701

• Development of hexadecyloxypropyl tenofovir (CMX157) for treatment of infection caused by wild-type and nucleoside/nucleotide-resistant HIV.

  Antimicrobial agents and chemotherapy 20100701

• Long-term outcomes of HIV-infected patients with <95% rates of adherence to nonnucleoside reverse-transcriptase inhibitors.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100701

• [d4U]-spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase.

  Bioorganic & medicinal chemistry 20100701

• Self-reported adherence to HAART in South-Eastern Nigeria is related to patients' use of pill box.

  SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance 20100701

• New trends in nucleoside biotechnology.

  Acta naturae 20100701

• Extensive hypertrophic lichen planus in an HIV positive patient.

  Dermatology online journal 20100615

• Using electronic drug monitor feedback to improve adherence to antiretroviral therapy among HIV-positive patients in China.

  AIDS and behavior 20100601

• Successful paediatric HIV treatment in rural primary care in Africa.

  Archives of disease in childhood 20100601

• The synthesis and NMR investigation on novel boron derivatives of stavudine.

  Bioorganic chemistry 20100601

• Connection domain mutations in treatment-experienced patients in the OPTIMA trial.

  Journal of acquired immune deficiency syndromes (1999) 20100601

• Risk factors in human immunodeficiency virus/acquired immunodeficiency syndrome patients undergoing antiretroviral therapy in the state of Pernambuco, Brazil: a case-control study.

  Metabolic syndrome and related disorders 20100601

• Antiretroviral therapy and bone mineral measurements in HIV-infected youths.

  Bone 20100601

• Limited sampling models to predict the pharmacokinetics of nevirapine, stavudine, and lamivudine in HIV-infected children treated with pediatric fixed-dose combination tablets.

  Therapeutic drug monitoring 20100601

• Early versus delayed initiation of antiretroviral therapy for concurrent HIV infection and cryptococcal meningitis in sub-saharan Africa.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100601

• The benefit of supplementary feeding for wasted Malawian adults initiating ART.

  AIDS care 20100601

• Age-related changes in plasma concentrations of the HIV protease inhibitor lopinavir.

  AIDS research and human retroviruses 20100601

• Why are antiretroviral treatment patients lost to follow-up? A qualitative study from South Africa.

  Tropical medicine & international health : TM & IH 20100601

• Strategies to improve patient retention on antiretroviral therapy in sub-Saharan Africa.

  Tropical medicine & international health : TM & IH 20100601

• Cost of using a patient tracer to reduce loss to follow-up and ascertain patient status in a large antiretroviral therapy program in Johannesburg, South Africa.

  Tropical medicine & international health : TM & IH 20100601

• Adverse drug reactions to antiretroviral therapy in AIDS patients at a tertiary care hospital in India: A prospective observational study.

  Indian journal of medical sciences 20100601

• Hepatitis C seropositivity is not a risk factor for sensory neuropathy among patients with HIV.

  Neurology 20100511

• Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells.

  Toxicological sciences : an official journal of the Society of Toxicology 20100501

• The frequency and reasons for antiretroviral switching with specific antiretroviral associations: the SWITCH study.

  Antiviral research 20100501

• Superior efficacy of new medicines?

  European journal of clinical pharmacology 20100501

• HIV neuropathy in South Africans: frequency, characteristics, and risk factors.

  Muscle & nerve 20100501

• Analysis of drug resistance in children receiving antiretroviral therapy for treatment of HIV-1 infection in Uganda.

  AIDS research and human retroviruses 20100501

• Economic evaluation of ART in resource-limited countries.

  Current opinion in HIV and AIDS 20100501

• Disposition of [1'-(14)C]stavudine after oral administration to humans.

  Drug metabolism and disposition: the biological fate of chemicals 20100401

• Ubisol-Aqua: coenzyme Q10 prevents antiretroviral toxic neuropathy in an in vitro model.

  Current HIV research 20100401

• Suboptimal etravirine activity is common during failure of nevirapine-based combination antiretroviral therapy in a cohort infected with non-B subtype HIV-1.

  Current HIV research 20100401

• Relationship between HIV/Highly active antiretroviral therapy (HAART)-associated lipodystrophy syndrome and stavudine-triphosphate intracellular levels in patients with stavudine-based antiretroviral regimens.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100401

• Assessment of the prevalence of distal symmetrical polyneuropathy and its risk factors among HAART-treated and untreated HIV infected individuals.

  Ethiopian medical journal 20100401

• HIV-1 RT Inhibitors with a Novel Mechanism of Action: NNRTIs that Compete with the Nucleotide Substrate.

  Viruses 20100401

• Upregulation of nuclear-encoded mitochondrial LON protease in HAART-treated HIV-positive patients with lipodystrophy: implications for the pathogenesis of the disease.

  AIDS (London, England) 20100327

• [Evolution of HIV-1 drug resistance in patients failing combination antiretroviral therapy].

  Zhonghua yi xue za zhi 20100309

• White blood.

  Lancet (London, England) 20100306

• Construction and validation of a yeast model system for studying in vivo the susceptibility to nucleoside analogues of DNA polymerase gamma allelic variants.

  Mitochondrion 20100301

• Central nervous system T-cell lymphoma in acquired immunodeficiency syndrome.

  British journal of haematology 20100301

• Real time PCR for rapid determination of susceptibility of adenovirus to antiviral drugs.

  Journal of virological methods 20100301

• Association between cervical dysplasia and human papillomavirus in HIV seropositive women from Johannesburg South Africa.

  Cancer causes & control : CCC 20100301

• Cloning, purification and characterisation of a recombinant purine nucleoside phosphorylase from Bacillus halodurans Alk36.

  Extremophiles : life under extreme conditions 20100301

• Antiviral drugs in wastewater and surface waters: a new pharmaceutical class of environmental relevance?

  Environmental science & technology 20100301

• Nucleoside analog stavudine depletes mitochondrial DNA with no organelle loss in mouse oocytes.

  Current HIV research 20100301

• Analysis of RT sequences of subtype C HIV-type 1 isolates from indian patients at failure of a first-line treatment according to clinical and/or immunological WHO guidelines.

  AIDS research and human retroviruses 20100301

• The silent epidemic of exclusive university licensing policies on compounds for neglected diseases and beyond.

  PLoS neglected tropical diseases 20100301

• [Durability and tolerability of long-term nevirapine-based HAART].

  Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20100301

• Simultaneous determination of stavudine and lamivudine in human plasma by high performance liquid chromatography and its application to a bioavailability study.

  The Southeast Asian journal of tropical medicine and public health 20100301

• Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100215

• Incidence and risk factors for chronic elevation of alanine aminotransferase levels in HIV-infected persons without hepatitis b or c virus co-infection.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100215

• Pharmacy students' knowledge of black box warnings.

  American journal of pharmaceutical education 20100210

• HIV infection of the male genital tract--consequences for sexual transmission and reproduction.

  International journal of andrology 20100201

• Risk factors for and clinical characteristics of severe hyperlactataemia in patients receiving antiretroviral therapy: a case-control study.

  HIV medicine 20100201

• Stavudine- and nevirapine-related drug toxicity while on generic fixed-dose antiretroviral treatment: incidence, timing and risk factors in a three-year cohort in Kigali, Rwanda.

  Transactions of the Royal Society of Tropical Medicine and Hygiene 20100201

• Synthesis and antiviral activity of boranophosphonate isosteres of AZT and d4T monophosphates.

  European journal of medicinal chemistry 20100201

• Low-abundance HIV species and their impact on mutational profiles in patients with virological failure on once-daily abacavir/lamivudine/zidovudine and tenofovir.

  The Journal of antimicrobial chemotherapy 20100201

• Co-administration of fluconazole increases nevirapine concentrations in HIV-infected Ugandans.

  The Journal of antimicrobial chemotherapy 20100201

• Risk of myocardial infarction in patients with HIV infection exposed to specific individual antiretroviral drugs from the 3 major drug classes: the data collection on adverse events of anti-HIV drugs (D:A:D) study.

  The Journal of infectious diseases 20100201

• Cost-effectiveness of tenofovir as first-line antiretroviral therapy in India.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100201

• Synthesis of fluorescent nucleoside analogs as probes for 2'-deoxyribonucleoside kinases.

  Bioorganic & medicinal chemistry letters 20100201

• Causes of acute hospitalization in adolescence: burden and spectrum of HIV-related morbidity in a country with an early-onset and severe HIV epidemic: a prospective survey.

  PLoS medicine 20100201

• Effectiveness of non-nucleoside reverse-transcriptase inhibitor-based antiretroviral therapy in women previously exposed to a single intrapartum dose of nevirapine: a multi-country, prospective cohort study.

  PLoS medicine 20100201

• Acute psychosis under efavirenz in a HIV patient.

  La Tunisie medicale 20100201

• Risk factors, management and outcomes of adverse drug reactions in adult patients on antiretrovirals at Kenyatta National Hospital, Nairobi.

  East African medical journal 20100201

• Tautomerism of the natural thymidine nucleoside and the antiviral analogue D4T. Structure and influence of an aqueous environment using MP2 and DFT methods.

  Physical chemistry chemical physics : PCCP 20100128

• DAART for human immunodeficiency virus-infected patients: Studying subjects not at risk for nonadherence and use of untested interventions.

  Archives of internal medicine 20100111

• Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial.

  Lancet (London, England) 20100109

• Antiretroviral treatment changes in adults from Côte d'Ivoire: the roles of tuberculosis and pregnancy.

  AIDS (London, England) 20100102

• Early nucleoside reverse transcriptase inhibitors for the treatment of HIV: a brief history of stavudine (D4T) and its comparison with other dideoxynucleosides.

  Antiviral research 20100101

• Synthesis, nanosizing and in vitro drug release of a novel anti-HIV polymeric prodrug: chitosan-O-isopropyl-5'-O-d4T monophosphate conjugate.

  Bioorganic & medicinal chemistry 20100101

• Management of individuals requiring antiretroviral therapy and TB treatment.

  Current opinion in HIV and AIDS 20100101

• Are patents impeding medical care and innovation?

  PLoS medicine 20100101

• Modelling imperfect adherence to HIV induction therapy.

  BMC infectious diseases 20100101

• The mitochondria-independent cytotoxic effect of nelfinavir on leukemia cells can be enhanced by sorafenib-mediated mcl-1 downregulation and mitochondrial membrane destabilization.

  Molecular cancer 20100101

• Only slight impact of predicted replicative capacity for therapy response prediction.

  PloS one 20100101

• The tuberculosis challenge in a rural South African HIV programme.

  BMC infectious diseases 20100101

• Antiretroviral (ARV) Therapy in Resource Poor Countries: What do we Need in Real Life?

  The open AIDS journal 20100101

• Towards a Patent Pool for HIV Medicines: The Background.

  The open AIDS journal 20100101

• Patent Pooling for Promoting Access to Antiretroviral Drugs (ARVs) - A Strategic Option for India.

  The open AIDS journal 20100101

• Cerebral FDG-PET scanning abnormalities in optimally treated HIV patients.

  Journal of neuroinflammation 20100101

• Pharmacokinetics of generic and trade formulations of lamivudine, stavudine and nevirapine in HIV-infected Malawian children.

  Antiviral therapy 20100101

• Tenofovir-associated bone density loss.

  Therapeutics and clinical risk management 20100101

• Profile of etravirine for the treatment of HIV infection.

  Therapeutics and clinical risk management 20100101

• Nevirapine-associated early hepatotoxicity: incidence, risk factors, and associated mortality in a primary care ART programme in South Africa.

  PloS one 20100101

• Extracting causal relations on HIV drug resistance from literature.

  BMC bioinformatics 20100101

• Hepatotoxicity and effectiveness of a Nevirapine-based antiretroviral therapy in HIV-infected patients with or without viral hepatitis B or C infection in Cameroon.

  BMC public health 20100101

• Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging.

  Particle and fibre toxicology 20100101

• Designing ARVs Patent Pool Up to Trade & Policy Evolutionary Dynamics.

  The open AIDS journal 20100101

• Antiretroviral treatment adherence among HIV patients in KwaZulu-Natal, South Africa.

  BMC public health 20100101

• Technology Development Through Pooling ARV Drug Patents: A Vision from China.

  The open AIDS journal 20100101

• Decreased NK Cell FcRgamma in HIV-1 infected individuals receiving combination antiretroviral therapy: a cross sectional study.

  PloS one 20100101

• Current antibody-based immunoassay algorithm failed to confirm three late-stage AIDS cases in China: case report.

  Virology journal 20100101

• Prevalence of anaemia in HIV-infected children at the University of Abuja Teaching Hospital, Gwagwalada.

  Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria 20100101

• Abacavir/lamivudine combination in the treatment of HIV: a review.

  Therapeutics and clinical risk management 20100101

• A cluster randomized trial of routine HIV-1 viral load monitoring in Zambia: study design, implementation, and baseline cohort characteristics.

  PloS one 20100101

• High survival and treatment success sustained after two and three years of first-line ART for children in Cambodia.

  Journal of the International AIDS Society 20100101

• The UNITAID Patent Pool Initiative: Bringing Patents Together for the Common Good.

  The open AIDS journal 20100101

• Effects of CYP2B6 G516T polymorphisms on plasma efavirenz and nevirapine levels when co-administered with rifampicin in HIV/TB co-infected Thai adults.

  AIDS research and therapy 20100101

• Clinical deterioration during antituberculosis treatment in Africa: incidence, causes and risk factors.

  BMC infectious diseases 20100101

• When to start antiretroviral therapy in resource-limited settings: a human rights analysis.

  BMC international health and human rights 20100101

• Raltegravir is a potent inhibitor of XMRV, a virus implicated in prostate cancer and chronic fatigue syndrome.

  PloS one 20100101

• Positive and negative drug selection pressures on the N348I connection domain mutation: new insights from in vivo data.

  Antiviral therapy 20100101

• Pharmacokinetic characterization of three doses of tipranavir boosted with ritonavir on highly active antiretroviral therapy in treatment-experienced HIV-1 patients.

  HIV clinical trials 20100101

• A meta-analysis of six placebo-controlled trials of thiazolidinedione therapy for HIV lipoatrophy.

  HIV clinical trials 20100101

• The cost-effectiveness of directly observed highly-active antiretroviral therapy in the third trimester in HIV-infected pregnant women.

  PloS one 20100101

• Increasing rates of obesity among HIV-infected persons during the HIV epidemic.

  PloS one 20100101

• 'I will not let my HIV status stand in the way.' Decisions on motherhood among women on ART in a slum in Kenya- a qualitative study.

  BMC women's health 20100101

• A randomized, controlled, trial of short cycle intermittent compared to continuous antiretroviral therapy for the treatment of HIV infection in Uganda.

  PloS one 20100101

• The influence of HAART on the efficacy and safety of pegylated interferon and ribavirin therapy for the treatment of chronic HCV infection in HIV-positive Individuals.

  European journal of medical research 20100101

• Prevalence and risk factors for significant liver fibrosis among HIV-monoinfected patients.

  BMC infectious diseases 20100101

• Incident tuberculosis during antiretroviral therapy contributes to suboptimal immune reconstitution in a large urban HIV clinic in sub-Saharan Africa.

  PloS one 20100101

• Stavudine-induced hyperlactatemia/lactic acidosis at a tertiary communicable diseases clinic in South Africa.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20100101

• Semen may harbor HIV despite effective HAART: another piece in the puzzle.

  PloS one 20100101

• Patient retention and adherence to antiretrovirals in a large antiretroviral therapy program in Nigeria: a longitudinal analysis for risk factors.

  PloS one 20100101

• Intervening in global markets to improve access to HIV/AIDS treatment: an analysis of international policies and the dynamics of global antiretroviral medicines markets.

  Globalization and health 20100101

• Reduced referral and case fatality rates for severe symptomatic hyperlactataemia in a South African public sector antiretroviral programme: a retrospective observational study.

  AIDS research and therapy 20100101

• Serum phosphate predicts early mortality in adults starting antiretroviral therapy in Lusaka, Zambia: a prospective cohort study.

  PloS one 20100101

• Steady-state nevirapine, lamivudine and stavudine levels in Malawian HIV-infected children on antiretroviral therapy using split Triomune 30 tablets.

  Antiviral therapy 20100101

• Proteomic analysis identifies prohibitin down-regulation as a crucial event in the mitochondrial damage observed in HIV-infected patients.

  Antiviral therapy 20100101

• Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection.

  AIDS research and therapy 20100101

• Depression symptoms and cognitive function among individuals with advanced HIV infection initiating HAART in Uganda.

  BMC psychiatry 20100101

• Nucleic acid template and the risk of a PCR-Induced HIV-1 drug resistance mutation.

  PloS one 20100101

• Hidden drug resistant HIV to emerge in the era of universal treatment access in Southeast Asia.

  PloS one 20100101

• A decline in new HIV infections in South Africa: estimating HIV incidence from three national HIV surveys in 2002, 2005 and 2008.

  PloS one 20100101

• Generic and low dose antiretroviral therapy in adults and children: implication for scaling up treatment in resource limited settings.

  AIDS research and therapy 20100101

• Incidence and risk factors of severe adverse events with nevirapine-based antiretroviral therapy in HIV-infected women. MTCT-Plus program, Abidjan, Côte d'Ivoire.

  BMC infectious diseases 20100101

• Virologic and immunologic outcomes in HIV-infected Cambodian children after 18 months of highly active antiretroviral therapy (HAART).

  The Southeast Asian journal of tropical medicine and public health 20100101

• Glycated haemoglobin in diabetic women with and without HIV infection: data from the Women's Interagency HIV Study.

  Antiviral therapy 20100101

• Pyrimidine deoxynucleoside and nucleoside reverse transcriptase inhibitor metabolism in the perfused heart and isolated mitochondria.

  Antiviral therapy 20100101

• Tamoxifen enhances the cytotoxic effects of nelfinavir in breast cancer cells.

  Breast cancer research : BCR 20100101

• Financing equitable access to antiretroviral treatment in South Africa.

  BMC health services research 20100101

• Risk factor analyses for immune reconstitution inflammatory syndrome in a randomized study of early vs. deferred ART during an opportunistic infection.

  PloS one 20100101

• Development of a liposomal nanodelivery system for nevirapine.

  Journal of biomedical science 20100101

• Dynamics of HIV-1 quasispecies during antiviral treatment dissected using ultra-deep pyrosequencing.

  PloS one 20100101

• One step forward, one step sideways? Expanding research capacity for neglected diseases.

  BMC international health and human rights 20100101

• Lack of association between stavudine exposure and lipoatrophy, dysglycaemia, hyperlactataemia and hypertriglyceridaemia: a prospective cross sectional study.

  AIDS research and therapy 20100101

• Bioanalytical method development and validation for the simultaneous estimation of lamivudine and stavudine in human plasma by HPLC.

  Acta poloniae pharmaceutica 20100101

• Low haemoglobin predicts early mortality among adults starting antiretroviral therapy in an HIV care programme in South Africa: a cohort study.

  BMC public health 20100101

• Identifying individuals with virologic failure after initiating effective antiretroviral therapy: The surprising value of mean corpuscular hemoglobin in a cross-sectional study.

  AIDS research and therapy 20100101

• Secular trends in pediatric antiretroviral treatment programs in rural and urban Zambia: a retrospective cohort study.

  BMC pediatrics 20100101

• Immunological response to highly active antiretroviral therapy following treatment for prevention of mother to child transmission of HIV-1: a study in Côte d'Ivoire.

  Journal of the International AIDS Society 20100101

• Continuing or adding IL-2 in patients treated with antiretroviral therapy (ACTG Protocol A5051, a rollover trial of ACTG Protocol A328).

  AIDS research and therapy 20100101

• Growth, immune and viral responses in HIV infected African children receiving highly active antiretroviral therapy: a prospective cohort study.

  BMC pediatrics 20100101

• Discontinuation of standard first-line antiretroviral therapy in a cohort of 1434 Malawian children.

  Journal of the International AIDS Society 20100101

• Presence of the CYP2B6 516G> T polymorphism, increased plasma Efavirenz concentrations and early neuropsychiatric side effects in South African HIV-infected patients.

  AIDS research and therapy 20100101

• Lipoprotein levels and cardiovascular risk in HIV-infected and uninfected Rwandan women.

  AIDS research and therapy 20100101

• Occurrence of stavudine-induced lactic acidosis in 3 members of an African family.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20100101

• Susceptibility of the human retrovirus XMRV to antiretroviral inhibitors.

  Retrovirology 20100101

• Association between HIV replication and serum leptin levels: an observational study of a cohort of HIV-1-infected South African women.

  Journal of the International AIDS Society 20100101

• A lifeline to treatment: the role of Indian generic manufacturers in supplying antiretroviral medicines to developing countries.

  Journal of the International AIDS Society 20100101

• Assessing the performance of a computer-based policy model of HIV and AIDS.

  PloS one 20100101

• A prospective cohort study of immunologic and virologic outcomes in patients with HIV/AIDS and hepatitis virus co-infection in Jos, Nigeria.

  Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria 20100101

• Knowledge and adherence to antiretroviral therapy among adult people living with HIV/AIDS treated in the health care centers of the association 'Espoir Vie Togo' in Togo, West Africa.

  BMC clinical pharmacology 20100101

• Remission of severe restless legs syndrome and periodic limb movements in sleep after bilateral excision of multiple foot neuromas: a case report.

  Journal of medical case reports 20100101

• Economic outcomes of patients receiving antiretroviral therapy for HIV/AIDS in South Africa are sustained through three years on treatment.

  PloS one 20100101

• Cost-effectiveness of HIV testing referral strategies among tuberculosis patients in India.

  PloS one 20100101

• Clinical, virological and immunological responses in Danish HIV patients receiving raltegravir as part of a salvage regimen.

  Clinical epidemiology 20100101

• Population uptake of antiretroviral treatment through primary care in rural South Africa.

  BMC public health 20100101

• Aging, human immunodeficiency virus, and bone health.

  Clinical interventions in aging 20100101

• Lymphoma in HIV patients: Varied presentations.

  Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology 20100101

• Renal impairment after switching from stavudine/lamivudine to tenofovir/lamivudine in NNRTI-based antiretroviral regimens.

  AIDS research and therapy 20100101

• What happens to ART-eligible patients who do not start ART? Dropout between screening and ART initiation: a cohort study in Karonga, Malawi.

  BMC public health 20100101

• Task shifting in Mozambique: cross-sectional evaluation of non-physician clinicians' performance in HIV/AIDS care.

  Human resources for health 20100101

• Patients present earlier and survival has improved, but pre-ART attrition is high in a six-year HIV cohort data from Ethiopia.

  PloS one 20100101

• Prevalence of transmitted drug resistance and impact of transmitted resistance on treatment success in the German HIV-1 Seroconverter Cohort.

  PloS one 20100101

• A comparative analysis of HIV drug resistance interpretation based on short reverse transcriptase sequences versus full sequences.

  AIDS research and therapy 20100101

• The global pediatric antiretroviral market: analyses of product availability and utilization reveal challenges for development of pediatric formulations and HIV/AIDS treatment in children.

  BMC pediatrics 20100101

• Safety and efficacy after switch to a saquinavir-containing antiretroviral regimen in protease inhibitor pretreated HIV-positive patients.

  European journal of medical research 20100101

• Progress in antiretroviral drug delivery using nanotechnology.

  International journal of nanomedicine 20100101

• Population-level reduction in adult mortality after extension of free anti-retroviral therapy provision into rural areas in northern Malawi.

  PloS one 20100101

• Impact of drug stock-outs on death and retention to care among HIV-infected patients on combination antiretroviral therapy in Abidjan, Côte d'Ivoire.

  PloS one 20100101

• Predictors of adherence to antiretroviral therapy among people living with HIV/AIDS in resource-limited setting of southwest ethiopia.

  AIDS research and therapy 20100101

• Reduced dose of stavudine and lipoatrophy in HIV-infected patients in Cameroon.

  Antiviral therapy 20100101

• Determinants of survival in adult HIV patients on antiretroviral therapy in Oromiyaa, Ethiopia.

  Global health action 20100101

• Baseline severe anaemia should not preclude use of zidovudine in antiretroviral-eligible patients in resource-limited settings.

  Journal of the International AIDS Society 20100101

• Long-term adherence to antiretroviral treatment and program drop-out in a high-risk urban setting in sub-Saharan Africa: a prospective cohort study.

  PloS one 20100101

• Antiretroviral therapy optimisation without genotype resistance testing: a perspective on treatment history based models.

  PloS one 20100101

• HIV-infected former plasma donors in rural Central China: from infection to survival outcomes, 1985-2008.

  PloS one 20100101

• Gender-related mortality for HIV-infected patients on highly active antiretroviral therapy (HAART) in rural Uganda.

  International journal of women's health 20100101

• Adherence to antiretroviral therapy in an urban, free-care HIV clinic in Guatemala City, Guatemala.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20100101

• Contraceptive use and method preference among women in Soweto, South Africa: the influence of expanding access to HIV care and treatment services.

  PloS one 20100101

• Uridine metabolism in HIV-1-infected patients: effect of infection, of antiretroviral therapy and of HIV-1/ART-associated lipodystrophy syndrome.

  PloS one 20100101

• Decrease of vitamin D concentration in patients with HIV infection on a non nucleoside reverse transcriptase inhibitor-containing regimen.

  AIDS research and therapy 20100101

• Can herpes simplex virus type 2 suppression slow HIV disease progression: a study protocol for the VALacyclovir In Delaying Antiretroviral Treatment Entry (VALIDATE) trial.

  Trials 20100101

• Increased vulnerability of rural children on antiretroviral therapy attending public health facilities in South Africa: a retrospective cohort study.

  Journal of the International AIDS Society 20100101

• Synthesis and in vitro human skin penetration of oligo- and polymeric ethylene glycol carbonates of zidovudine and stavudine.

  Arzneimittel-Forschung 20100101

• Frequency of HIV-1 viral load monitoring of patients initially successfully treated with combination antiretroviral therapy.

  PloS one 20100101

• Comparison of antiviral activity of regimens containing nucleos(t)ide (NUC) Pairs in HIV-Infected Patients Initiating REScue therapy (The NUCREST Study).

  HIV clinical trials 20100101

• Varied sensitivity to therapy of HIV-1 strains in CD4+ lymphocyte sub-populations upon ART initiation.

  AIDS research and therapy 20100101

• Experiencing antiretroviral adherence: helping healthcare staff better understand adherence to paediatric antiretrovirals.

  Journal of the International AIDS Society 20100101

• The importance of clinic attendance in the first six months on antiretroviral treatment: a retrospective analysis at a large public sector HIV clinic in South Africa.

  Journal of the International AIDS Society 20100101

• Antiadenoviral effects of N-chlorotaurine in vitro confirmed by quantitative polymerase chain reaction methods.

  Clinical ophthalmology (Auckland, N.Z.) 20100101

• Utility of quantitative sensory testing and screening tools in identifying HIV-associated peripheral neuropathy in Western Kenya: pilot testing.

  PloS one 20100101

• Immune restoration disease and changes in CD4+ T-cell count in HIV- infected patients during highly active antiretroviral therapy at Zewditu memorial hospital, Addis Ababa, Ethiopia.

  AIDS research and therapy 20100101

• Proteochemometric modeling of the susceptibility of mutated variants of the HIV-1 virus to reverse transcriptase inhibitors.

  PloS one 20100101

• Trends in CD4 counts in HIV-infected patients with HIV viral load monitoring while on combination antiretroviral treatment: results from The TREAT Asia HIV Observational Database.

  BMC infectious diseases 20100101

• Pharmacological treatment of painful HIV-associated sensory neuropathy: a systematic review and meta-analysis of randomised controlled trials.

  PloS one 20100101

• Pseudogout Associated Hip Pain in a Patient with HIV Infection.

  Case reports in medicine 20100101

• Simultaneous spectrophotometric estimation of tenofovir disoproxil fumarate and Lamivudine in three component tablet formulation containing efavirenz.

  Indian journal of pharmaceutical sciences 20100101

• Computational Analysis of Molecular Interaction Networks Underlying Change of HIV-1 Resistance to Selected Reverse Transcriptase Inhibitors.

  Bioinformatics and biology insights 20100101

• Efficacy and Safety of Abacavir/Lamivudine/Zidovudine Plus Tenofovir in HBV/HIV-1 Coinfected Adults: 48-Week Data.

  The open AIDS journal 20100101

• Effect of Maternal HIV-1 Status and Antiretroviral Drugs on Haematological Profiles of South African Infants in Early Life.

  The open AIDS journal 20100101

• UV Spectrophotometric Method for Assay of the Anti-Retroviral Agent Lamivudine in Active Pharmaceutical Ingredient and in its Tablet Formulation.

  Journal of young pharmacists : JYP 20100101

• Postexposure prophylaxis for deadly bloodborne viral infections.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20100101

• Simplified Assessment of Antiretroviral Adherence and Prediction of Virological Efficacy in HIV-Infected Patients in Cambodia.

  AIDS research and treatment 20100101

• Clinic Attendance for Medication Refills and Medication Adherence amongst an Antiretroviral Treatment Cohort in Uganda: A Prospective Study.

  AIDS research and treatment 20100101

• Lipid Metabolism and Cardiovascular Risk in HIV-1 Infection and HAART: Present and Future Problems.

  Cholesterol 20100101

• Micronuclei induced by reverse transcriptase inhibitors in mononucleated and binucleated cells as assessed by the cytokinesis-block micronucleus assay.

  Genetics and molecular biology 20100101

• Raltegravir in combination with other antiretroviral agents for the treatment of HIV infection.

  Infection and drug resistance 20100101

• The use of anti-tuberculosis therapy for latent TB infection.

  Infection and drug resistance 20100101

• Beyond the black box: drug- and device-associated hypersensitivity events.

  Drug, healthcare and patient safety 20100101

• Tenofovir-associated renal dysfunction in clinical practice: An observational cohort from western India.

  Indian journal of sexually transmitted diseases and AIDS 20100101

• Zidovudine-induced myopathy: A study in Indian patients.

  Journal of neurosciences in rural practice 20100101

• Adherence to antiretroviral therapy in Nigeria: an overview of research studies and implications for policy and practice.

  HIV/AIDS (Auckland, N.Z.) 20100101

• An update on the use of Atripla in the treatment of HIV in the United States.

  HIV/AIDS (Auckland, N.Z.) 20100101

• Long-term treatment of patients with HIV-1: the role of atazanavir.

  HIV/AIDS (Auckland, N.Z.) 20100101

• New and emerging agents in the management of lipodystrophy in HIV-infected patients.

  HIV/AIDS (Auckland, N.Z.) 20100101

• Oral manifestations of HIV.

  Contemporary clinical dentistry 20100101

• Antimicrobial evaluation of novel substituted pyrimidinopyrazoles and pyrimidinotriazoles.

  Journal of advanced pharmaceutical technology & research 20100101

• Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: a cluster-randomised equivalence trial.

  Lancet (London, England) 20091219

• Highly active antiretroviral therapy drugs inhibit in vitro cholesterol efflux from human macrophage-derived foam cells.

  Laboratory investigation; a journal of technical methods and pathology 20091201

• Pharmacokinetics of nevirapine in HIV-infected children with and without malnutrition receiving divided adult fixed-dose combination tablets.

  The Journal of antimicrobial chemotherapy 20091201

• Risk of extended viral resistance in human immunodeficiency virus-1-infected Mozambican children after first-line treatment failure.

  The Pediatric infectious disease journal 20091201

• The hemostatic balance in HIV-infected patients with and without antiretroviral therapy: partial restoration with antiretroviral therapy.

  AIDS patient care and STDs 20091201

• Antiretroviral genotypic resistance mutations in HIV-1 infected Korean patients with virologic failure.

  Journal of Korean medical science 20091201

• Early and late direct costs in a Southern African antiretroviral treatment programme: a retrospective cohort analysis.

  PLoS medicine 20091201

• [Chronic abdominal pain and fever in an Ivoirian woman: Mycobacterium avium-intracellulare duodenitis in an AIDS patient in Abidjan, Cote d'Ivoire].

  Medecine tropicale : revue du Corps de sante colonial 20091201

• Thymidine analogue resistance suppression by V75I of HIV-1 reverse transcriptase: effects of substituting valine 75 on stavudine excision and discrimination.

  The Journal of biological chemistry 20091120

• An antibody-recruiting small molecule that targets HIV gp120.

  Journal of the American Chemical Society 20091118

• Safe substitution to zidovudine among HIV-infected patients initiated on stavudine-containing highly active antiretroviral therapy from a resource-limited setting.

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20091101

• Synthesis and in vitro transdermal penetration of methoxypoly(ethylene glycol) carbonate derivatives of stavudine.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20091101

• Bridging the gap between adult and paediatric outcomes in HIV-1 vertically infected children: a single-centre comparison with adult data.

  Acta paediatrica (Oslo, Norway : 1992) 20091101

• A rosiglitazone-induced increase in adiponectin does not improve glucose metabolism in HIV-infected patients with overt lipoatrophy.

  American journal of physiology. Endocrinology and metabolism 20091101

• Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile.

  Antimicrobial agents and chemotherapy 20091101

• Efavirenz: a decade of clinical experience in the treatment of HIV.

  The Journal of antimicrobial chemotherapy 20091101

• Modified directly observed therapy to improve HIV treatment outcomes: little impact with potent, once-daily therapy in unselected antiretroviral-naïve patients.

  Current HIV/AIDS reports 20091101

• PENTA 2009 guidelines for the use of antiretroviral therapy in paediatric HIV-1 infection.

  HIV medicine 20091101

• Human immunodeficiency virus type 1 subtypes prevalence in central China.

  Yonsei medical journal 20091031

• Reflections: neurology and the humanities: reflections for October.

  Neurology 20091013

• Antiretroviral compounds and cholesterol efflux from macrophages.

  Atherosclerosis 20091001

• Centrosome amplification induced by the antiretroviral nucleoside reverse transcriptase inhibitors lamivudine, stavudine, and didanosine.

  Environmental and molecular mutagenesis 20091001

• Dissection of regenerating T-Cell responses against tuberculosis in HIV-infected adults sensitized by Mycobacterium tuberculosis.

  American journal of respiratory and critical care medicine 20091001

• Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria.

  Journal of acquired immune deficiency syndromes (1999) 20091001

• Evaluation of HIV/AIDS clinical care quality: the case of a referral hospital in North West Ethiopia.

  International journal for quality in health care : journal of the International Society for Quality in Health Care 20091001

• A comparison of HIV-1 drug susceptibility as provided by conventional phenotyping and by a phenotype prediction tool based on viral genotype.

  Journal of medical virology 20091001

• Prevalence of and clinical factors associated with lipoatrophy in HIV-infected Koreans receiving highly active antiretroviral therapy.

  The Tohoku journal of experimental medicine 20091001

• Assessment of neuropathic pain in primary care.

  The American journal of medicine 20091001

• Task shifting for scale-up of HIV care: evaluation of nurse-centered antiretroviral treatment at rural health centers in Rwanda.

  PLoS medicine 20091001

• Lipodystrophy and metabolic complications of highly active antiretroviral therapy.

  Indian journal of pediatrics 20091001

• Pharmacokinetics of lamivudine & stavudine in generic fixed-dose combinations in HIV-1 infected adults in India.

  The Indian journal of medical research 20091001

• A prospective, observational cohort study to elicit adverse effects of antiretroviral agents in a remote resource-restricted tribal population of Chhattisgarh.

  Indian journal of pharmacology 20091001

• Reply to 'kidney transplantation in a patient with HIV disease'.

  Indian journal of nephrology 20091001

• The effect of temperature and moisture on the amorphous-to-crystalline transformation of stavudine.

  International journal of pharmaceutics 20090908

• Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.

  Antimicrobial agents and chemotherapy 20090901

• Rate of accumulation of thymidine analogue mutations in patients continuing to receive virologically failing regimens containing zidovudine or stavudine: implications for antiretroviral therapy programs in resource-limited settings.

  The Journal of infectious diseases 20090901

• Interindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected Ghanaian patients: UGT2B7*1c is associated with faster zidovudine clearance and glucuronidation.

  Journal of clinical pharmacology 20090901

• Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates.

  Rapid communications in mass spectrometry : RCM 20090901

• The history of antiretrovirals: key discoveries over the past 25 years.

  Reviews in medical virology 20090901

• Changes in cognition during antiretroviral therapy: comparison of 2 different ranking systems to measure antiretroviral drug efficacy on HIV-associated neurocognitive disorders.

  Journal of acquired immune deficiency syndromes (1999) 20090901

• Reversible reduction of nevirapine plasma concentrations during rifampicin treatment in patients coinfected with HIV-1 and tuberculosis.

  Journal of acquired immune deficiency syndromes (1999) 20090901

• Efficacy and safety of atazanavir-ritonavir plus abacavir-lamivudine or tenofovir-emtricitabine in patients with hyperlipidaemia switched from a stable protease inhibitor-based regimen including one thymidine analogue.

  AIDS patient care and STDs 20090901

• FDA notifications. FDA gives tentative approval for stavudine, lamivudine & nevirapine tablet.

  AIDS alert 20090901

• 3-Substituted pyrazinone nucleosides--a new family of D4T analogues.

  Nucleosides, nucleotides & nucleic acids 20090901

• HIV suppression with stavudine 30 mg versus 40 mg in adults over 60 kg on antiretroviral therapy in South Africa.

  AIDS (London, England) 20090824

• Stavudine in antiretroviral therapy: is this the end?

  AIDS (London, England) 20090824

• Human immunodeficiency virus: 25 years of diagnostic and therapeutic strategies and their impact on hepatitis B and C virus.

  Medical microbiology and immunology 20090801

• A longitudinal study of the changes in body fat and metabolic parameters in a South African population of HIV-positive patients receiving an antiretroviral therapeutic regimen containing stavudine.

  AIDS research and human retroviruses 20090801

• [Therapeutic effect and safety evaluation on 6-year highly active antiretroviral therapy for Chinese HIV-1 infected patients].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20090801

• Longitudinal changes in regional fat content in HIV-infected children and adolescents.

  AIDS (London, England) 20090731

• Age and height predict neuropathy risk in patients with HIV prescribed stavudine.

  Neurology 20090728

• HIV clinics are halting enrolment of new patients as funding stalls, MSF warns.

  BMJ (Clinical research ed.) 20090720

• Gene expression and immunohistochemistry in adipose tissue of HIV type 1-infected patients with nucleoside analogue reverse-transcriptase inhibitor-associated lipoatrophy.

  The Journal of infectious diseases 20090715

• Modified directly observed antiretroviral therapy compared with self-administered therapy in treatment-naive HIV-1-infected patients: a randomized trial.

  Archives of internal medicine 20090713

• The rise and fall of K65R in a Portuguese HIV-1 Drug Resistance database, despite continuously increasing use of tenofovir.

  Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20090701

• Cytotoxicological analysis of a gp120 binding aptamer with cross-clade human immunodeficiency virus type 1 entry inhibition properties: comparison to conventional antiretrovirals.

  Antimicrobial agents and chemotherapy 20090701

• Genome-wide screen identifies drug-induced regulation of the gene giant axonal neuropathy (Gan) in a mouse model of antiretroviral-induced painful peripheral neuropathy.

  Biological research for nursing 20090701

• The effect of individual antiretroviral drugs on body composition in HIV-infected persons initiating highly active antiretroviral therapy.

  Journal of acquired immune deficiency syndromes (1999) 20090701

• Improvements in cheek volume in lipoatrophic individuals switching away from thymidine nucleoside reverse transcriptase inhibitors.

  HIV medicine 20090701

• Factors associated with renal dysfunction within an urban HIV-infected cohort in the era of highly active antiretroviral therapy.

  HIV medicine 20090701

• Focusing on quality patient care in the new global subsidy for malaria medicines.

  PLoS medicine 20090701

• An investigation into the anti-HIV activity of 2',3'-didehydro-2',3'-dideoxyuridine (d4U) and 2',3'-dideoxyuridine (ddU) phosphoramidate 'ProTide' derivatives.

  Organic & biomolecular chemistry 20090621

• The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities.

  The Journal of biological chemistry 20090612

• Doubly loaded cycloSaligenyl-pronucleotides - 5,5'-Bis-(cycloSaligenyl-2',3'-dideoxy-2',3'-didehydrothymidine monophosphates).

  Journal of medicinal chemistry 20090611

• Weight evolution in HIV-1 infected women in Rwanda after stavudine substitution due to lipoatrophy: comparison of zidovudine with tenofovir/abacavir.

  Transactions of the Royal Society of Tropical Medicine and Hygiene 20090601

• Hierarchical modeling gave plausible estimates of associations between metabolic syndrome and components of antiretroviral therapy.

  Journal of clinical epidemiology 20090601

• Adherence to first-line antiretroviral therapy affects non-virologic outcomes among patients on treatment for more than 12 months in Lusaka, Zambia.

  International journal of epidemiology 20090601

• Mitochondrial function, morphology and metabolic parameters improve after switching from stavudine to a tenofovir-containing regimen.

  The Journal of antimicrobial chemotherapy 20090601

• Lipodystrophy and metabolic disorders in HIV-1-infected adults on 4- to 9-year antiretroviral therapy in Senegal: a case-control study.

  Journal of acquired immune deficiency syndromes (1999) 20090601

• Tuberculosis treatment and risk of stavudine substitution in first-line antiretroviral therapy.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090601

• Metabolic outcomes in a randomized trial of nucleoside, nonnucleoside and protease inhibitor-sparing regimens for initial HIV treatment.

  AIDS (London, England) 20090601

• Drug resistance in the Chinese National Pediatric Highly Active Antiretroviral Therapy Cohort: implications for paediatric treatment in the developing world.

  International journal of STD & AIDS 20090601

• How much fat loss is needed for lipoatrophy to become clinically evident?

  AIDS research and human retroviruses 20090601

• Substituting tenofovir for stavudine in resource-limited settings: there are challenges ahead.

  AIDS (London, England) 20090515

• Mitochondrial DNA base excision repair and mitochondrial DNA mutation in human hepatic HuH-7 cells exposed to stavudine.

  Mutation research 20090512

• Assessment of mitochondrial toxicity by analysis of mitochondrial protein expression in mononuclear cells.

  Cytometry. Part B, Clinical cytometry 20090501

• Measuring and monitoring apoptosis and drug toxicity in HIV patients by ligation-mediated polymerase chain reaction.

  Journal of cellular and molecular medicine 20090501

• The transport of anti-HIV drugs across blood-CNS interfaces: summary of current knowledge and recommendations for further research.

  Antiviral research 20090501

• Correction of facial lipoatrophy using autologous fat transplants in HIV-infected adolescents.

  HIV medicine 20090501

• Response to zidovudine/didanosine-containing combination antiretroviral therapy among HIV-1 subtype C-infected adults in Botswana: two-year outcomes from a randomized clinical trial.

  Journal of acquired immune deficiency syndromes (1999) 20090501

• Peripheral and visceral fat changes following a treatment switch to a non-thymidine analogue or a nucleoside-sparing regimen in HIV-infected subjects with peripheral lipoatrophy: results of ACTG A5110.

  The Journal of antimicrobial chemotherapy 20090501

• Changes in body composition with ritonavir-boosted and unboosted atazanavir treatment in combination with Lamivudine and Stavudine: a 96-week randomized, controlled study.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090501

• Novel synthesis and in vitro drug release of polymeric prodrug: Chitosan-O-isopropyl-5'-O-d4T monophosphate conjugate.

  Bioorganic & medicinal chemistry letters 20090501

• Resistance to antiretrovirals in HIV-infected pregnant women.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20090501

• First-line antiretroviral therapy in resource-limited settings: time to reconsider?

  The Journal of infectious diseases 20090501

• Arthritis as the presenting feature of HIV infection in a child.

  The Journal of infection 20090501

• Generic stavudine approved.

  AIDS patient care and STDs 20090501

• Long-term CD4 cell count recovery among Thai naive HIV-infected patients initiating HAART at low CD4 cell count.

  Current HIV research 20090501

• Hyperalgesia induced by oral stavudine administration to rats does not depend on spinal neuronal cell death, or on spinal or systemic inflammatory cytokine secretion, or metabolic dysregulation.

  Neurotoxicology 20090501

• High rates of regimen change due to drug toxicity among a cohort of South Indian adults with HIV infection initiated on generic, first-line antiretroviral treatment.

  The Journal of the Association of Physicians of India 20090501

• Rationing antiretroviral therapy in Africa--treating too few, too late.

  The New England journal of medicine 20090430

• Timing of initiation of antiretroviral therapy in AIDS-free HIV-1-infected patients: a collaborative analysis of 18 HIV cohort studies.

  Lancet (London, England) 20090418

• Screening and monitoring antiretrovirals and antivirals in the serum of acquired immunodeficiency syndrome patients by micellar liquid chromatography.

  Journal of chromatography. A 20090417

• Molecularly imprinted polymer for analysis of zidovudine and stavudine in human serum by liquid chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090415

• Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV.

  International journal of antimicrobial agents 20090401

• Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3.

  American journal of physiology. Gastrointestinal and liver physiology 20090401

• Sequencing of therapy to avoid resistance and the need for new antiretroviral drugs in the treatment of HIV disease.

  Infectious disorders drug targets 20090401

• Peripheral neuropathy in HIV-positive patients at an antiretroviral clinic in Lilongwe, Malawi.

  Tropical doctor 20090401

• [Establishment of pharmacological evaluation system for non-nucleoside reverse-transcriptase inhibitors resistant HIV-1].

  Yao xue xue bao = Acta pharmaceutica Sinica 20090401

• Metabolic effects associated to the highly active antiretroviral therapy (HAART) in AIDS patients.

  The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20090401

• Long-term exposure to AZT, but not d4T, increases endothelial cell oxidative stress and mitochondrial dysfunction.

  Cardiovascular toxicology 20090301

• Mutagenic and recombinagenic effects of lamivudine and stavudine antiretrovirals in somatic cells of Drosophila melanogaster.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090301

• Efficacy of non-nucleoside reverse transcriptase inhibitor-based highly active antiretroviral therapy in Thai HIV-infected children aged two years or less.

  The Pediatric infectious disease journal 20090301

• Effect of nucleoside reverse transcriptase inhibitors on CD4 T-cell recovery in HIV-1-infected individuals receiving long-term fully suppressive combination antiretroviral therapy.

  HIV medicine 20090301

• Roles and mechanisms of human immunodeficiency virus protease inhibitor ritonavir and other anti-human immunodeficiency virus drugs in endothelial dysfunction of porcine pulmonary arteries and human pulmonary artery endothelial cells.

  The American journal of pathology 20090301

• Generic combination approved.

  AIDS patient care and STDs 20090301

• [Treatment of chronic hepatitis C in HIV-infected patients].

  Gastroenterologie clinique et biologique 20090301

• FDA notifications. FDA approves generic stavudine.

  AIDS alert 20090301

• Hepatitis B in HIV patients: what is the current treatment and what are the challenges?

  Journal of HIV therapy 20090301

• Plasma lipid profile in pregnant women with HIV receiving nevirapine.

  AIDS patient care and STDs 20090301

• Toxicogenomic biomarkers for liver toxicity.

  Journal of toxicologic pathology 20090301

• Simulation of the first hydration shell of nucleosides D4T and thymidine: structures obtained using MP2 and DFT methods.

  The journal of physical chemistry. B 20090226

• [Factors associated with hepatic steatosis in human immunodeficiency virus and hepatits C virus coinfected patients].

  Medicina clinica 20090221

• Development of dual-class antiretroviral drug resistance in a child coinfected with HIV and tuberculosis: a case report from KwaZulu-Natal, South Africa.

  Journal of tropical pediatrics 20090201

• Low prevalence of insulin resistance among HIV-infected children receiving nonnucleoside reverse transcriptase inhibitor-based highly active antiretroviral therapy in Thailand.

  HIV medicine 20090201

• In vitro analysis of synergism and antagonism of different nucleoside/nucleotide analogue combinations on the inhibition of human immunodeficiency virus type 1 replication.

  Journal of medical virology 20090201

• A prospective study evaluating clinical outcomes and costs of three NNRTI-based HAART regimens in Kerala, India.

  Journal of clinical pharmacy and therapeutics 20090201

• Use of Tris-hydroxymethyl aminomethane in severe lactic acidosis due to highly active antiretroviral therapy: a case report.

  Journal of clinical pharmacy and therapeutics 20090201

• Assessment of ultrasound for use in detecting lipoatrophy in HIV-infected patients taking combination antiretroviral therapy.

  AIDS patient care and STDs 20090201

• FDA notifications. FDA approved 3 generic formulations of stavudine.

  AIDS alert 20090201

• Three generic stavudine formulations approved.

  AIDS patient care and STDs 20090201

• [Atazanavir-induced nephrolithiasis].

  Enfermedades infecciosas y microbiologia clinica 20090201

• Role of NEDD8 in HIV-associated lipodystrophy.

  Differentiation; research in biological diversity 20090201

• [A study of HIV-related lipodystrophy syndrome in 55 HIV-infected Chinese adult patients].

  Zhonghua nei ke za zhi 20090201

• Benefits and risks of stavudine therapy for HIV-associated neurologic complications in Uganda.

  Neurology 20090113

• Three-year outcome data of second-line antiretroviral therapy in Ugandan adults: good virological response but high rate of toxicity.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20090101

• The effects of Thiazolidinediones on metabolic complications and Lipodystrophy in HIV-infected patients.

  PPAR research 20090101

• Invasive disease caused by nontuberculous mycobacteria, Tanzania.

  Emerging infectious diseases 20090101

• Antiretroviral-related adipocyte dysfunction and lipodystrophy in HIV-infected patients: Alteration of the PPARγ-dependent pathways.

  PPAR research 20090101

• Universal access: the benefits and challenges in bringing integrated HIV care to isolated and conflict affected populations in the Republic of Congo.

  Conflict and health 20090101

• An analysis of enzyme kinetics data for mitochondrial DNA strand termination by nucleoside reverse transcription inhibitors.

  PLoS computational biology 20090101

• Viruses and thyroiditis: an update.

  Virology journal 20090101

• Developing countries need better antiretroviral drugs.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20090101

• Explaining adherence success in sub-Saharan Africa: an ethnographic study.

  PLoS medicine 20090101

• Prescribing and using self-injectable antiretrovirals: how concordant are physician and patient perspectives?

  AIDS research and therapy 20090101

• Effects of the K65R and K65R/M184V reverse transcriptase mutations in subtype C HIV on enzyme function and drug resistance.

  Retrovirology 20090101

• Outcomes of a remote, decentralized health center-based HIV/AIDS antiretroviral program in Zambia, 2003 to 2007.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20090101

• Combination antiretroviral therapy in population affected by conflict: outcomes from large cohort in northern Uganda.

  BMJ (Clinical research ed.) 20090101

• Clinical deterioration during antitubercular treatment at a district hospital in South Africa: the importance of drug resistance and AIDS defining illnesses.

  PloS one 20090101

• Acute promyelocytic leukemia after whole brain irradiation of primary brain lymphoma in an HIV-infected patient.

  European journal of medical research 20090101

• Development and evaluation of a clinical algorithm to monitor patients on antiretrovirals in resource-limited settings using adherence, clinical and CD4 cell count criteria.

  Journal of the International AIDS Society 20090101

• Clinical evaluation of local ocular toxicity in candidate anti-adenoviral agents in vivo.

  Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20090101

• Hematologic changes associated with Zidovudine following single-drug substitution from stavudine in a home-based AIDS care program in rural Uganda.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20090101

• [A fixed dose anti-HIV combination for the poor? Triomune].

  Revue medicale de Liege 20090101

• Adherence to the Mediterranean diet is associated with a lower risk of body-shape changes in Croatian patients treated with combination antiretroviral therapy.

  European journal of epidemiology 20090101

• Demographic, socio-economic, behavioral and clinical factors predicting virologic failure with generic fixed-dose combination antiretroviral therapy before universal health insurance coverage in northern Thailand.

  The Southeast Asian journal of tropical medicine and public health 20090101

• Is PPARγ a prospective player in HIV-1-associated bone disease?

  PPAR research 20090101

• A single-dose, randomized, open-label, two-period crossover bioequivalence study comparing a fixed-dose pediatric combination of lamivudine and stavudine tablet for oral suspension with individual liquid formulations in healthy adult male volunteers.

  Arzneimittel-Forschung 20090101

• A randomized, controlled trial of initial anti-retroviral therapy with abacavir/lamivudine/zidovudine twice-daily compared to atazanavir once-daily with lamivudine/zidovudine twice-daily in HIV-infected patients over 48 weeks (ESS100327, the ACTION Study).

  AIDS research and therapy 20090101

• Physical and emotional health outcomes after 12 months of public-sector antiretroviral treatment in the Free State Province of South Africa: a longitudinal study using structural equation modelling.

  BMC public health 20090101

• Efficacy and safety of darunavir and etravirine in an antiretroviral multi-experienced youth with vertically HIV-1 infection.

  European journal of medical research 20090101

• Comparative study of the persistence of anti-HIV activity of deoxynucleoside HIV reverse transcriptase inhibitors after removal from culture.

  AIDS research and therapy 20090101

• Quality of life and the impact of drug toxicities in a South African community-based antiretroviral programme.

  Journal of the International AIDS Society 20090101

• A new era of antiretroviral drug toxicity.

  Antiviral therapy 20090101

• Mutations in the thumb-connection and RNase H domain of HIV type-1 reverse transcriptase of antiretroviral treatment-experienced patients.

  Antiviral therapy 20090101

• Role of atazanavir in the treatment of HIV infection.

  Therapeutics and clinical risk management 20090101

• Early antiretroviral therapy reduces AIDS progression/death in individuals with acute opportunistic infections: a multicenter randomized strategy trial.

  PloS one 20090101

• HIV patients presenting common adverse drug events caused by highly active antiretroviral therapy in Tanzania.

  Tanzania journal of health research 20090101

• Supplementary feeding with either ready-to-use fortified spread or corn-soy blend in wasted adults starting antiretroviral therapy in Malawi: randomised, investigator blinded, controlled trial.

  BMJ (Clinical research ed.) 20090101

• Resistance profiles after different periods of exposure to a first-line antiretroviral regimen in a Cameroonian cohort of HIV type-1-infected patients.

  Antiviral therapy 20090101

• Zidovudine/lamivudine for HIV-1 infection contributes to limb fat loss.

  PloS one 20090101

• Risk factors for virological failure and subtherapeutic antiretroviral drug concentrations in HIV-positive adults treated in rural northwestern Uganda.

  BMC infectious diseases 20090101

• Comparison of brachial and carotid artery ultrasound for assessing extent of subclinical atherosclerosis in HIV: a prospective cohort study.

  AIDS research and therapy 20090101

• Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya.

  AIDS research and therapy 20090101

• Pregnancy outcomes among HIV-infected women undergoing antiretroviral therapy.

  The open AIDS journal 20090101

• Medication diaries do not improve outcomes with highly active antiretroviral therapy in Kenyan children: a randomized clinical trial.

  Journal of the International AIDS Society 20090101

• Low-abundance HIV drug-resistant viral variants in treatment-experienced persons correlate with historical antiretroviral use.

  PloS one 20090101

• Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection.

  PloS one 20090101

• Reduction of the HIV-1 reservoir in resting CD4+ T-lymphocytes by high dosage intravenous immunoglobulin treatment: a proof-of-concept study.

  AIDS research and therapy 20090101

• Development of a nursing intervention to facilitate optimal antiretroviral-treatment taking among people living with HIV.

  BMC health services research 20090101

• Virological efficacy and emergence of drug resistance in adults on antiretroviral treatment in rural Tanzania.

  BMC infectious diseases 20090101

• High prevalence of undiagnosed chronic kidney disease among at-risk population in Kinshasa, the Democratic Republic of Congo.

  BMC nephrology 20090101

• Host sequence motifs shared by HIV predict response to antiretroviral therapy.

  BMC medical genomics 20090101

• Clinical factors associated with plasma F2-isoprostane levels in HIV-infected adults.

  HIV clinical trials 20090101

• A model and risk score for predicting nevirapine-associated rash among HIV-infected patients: in settings of low CD4 cell counts and resource limitation.

  The open AIDS journal 20090101

• Mortality and loss-to-follow-up during the pre-treatment period in an antiretroviral therapy programme under normal health service conditions in Uganda.

  BMC public health 20090101

• Palliative care for HIV in the era of antiretroviral therapy availability: perspectives of nurses in Lesotho.

  BMC palliative care 20090101

• Excellent outcomes among HIV+ children on ART, but unacceptably high pre-ART mortality and losses to follow-up: a cohort study from Cambodia.

  BMC pediatrics 20090101

• Agreement between physicians and non-physician clinicians in starting antiretroviral therapy in rural Uganda.

  Human resources for health 20090101

• Pharmacotherapy of pediatric and adolescent HIV infection.

  Therapeutics and clinical risk management 20090101

• Five-year follow-up of children with perinatal HIV-1 infection receiving early highly active antiretroviral therapy.

  BMC infectious diseases 20090101

• Monitoring virologic responses to antiretroviral therapy in HIV-infected adults in Kenya: evaluation of a low-cost viral load assay.

  PloS one 20090101

• Renal impairment in a rural African antiretroviral programme.

  BMC infectious diseases 20090101

• Adverse drug reactions to nonnucleoside reverse transcriptase inhibitor-based antiretroviral regimen: a 24-week prospective study.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20090101

• Primary HIV-1 drug resistance and polymorphic patterns among injecting drug users (IDUs) in Chennai, Southern India.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20090101

• Evaluation of quantitative liver function tests in HIV-positive patients under anti-retroviral therapy.

  European journal of medical research 20090101

• A review of co-morbidity between infectious and chronic disease in Sub Saharan Africa: TB and diabetes mellitus, HIV and metabolic syndrome, and the impact of globalization.

  Globalization and health 20090101

• Perinatal acquisition of drug-resistant HIV-1 infection: mechanisms and long-term outcome.

  Retrovirology 20090101

• Early outcomes of MDR-TB treatment in a high HIV-prevalence setting in Southern Africa.

  PloS one 20090101

• Drugs associated with more suicidal ideations are also associated with more suicide attempts.

  PloS one 20090101

• Combined effect of C-reactive protein and stavudine on adipogenesis.

  Antiviral therapy 20090101

• The impact of combination antiretroviral therapy and its interruption on anxiety, stress, depression and quality of life in Thai patients.

  The open AIDS journal 20090101

• Antiretroviral treatment adherence and its determinants in Sub-Saharan Africa: a prospective study at Yaounde Central Hospital, Cameroon.

  AIDS research and therapy 20090101

• Pulmonary nocardiosis in the acquired immunodeficiency syndrome, computed tomographic findings: a case report.

  Cases journal 20090101

• Whole body bone scintigraphy in tenofovir-related osteomalacia: a case report.

  Journal of medical case reports 20090101

• Barriers to the care of HIV-infected children in rural Zambia: a cross-sectional analysis.

  BMC infectious diseases 20090101

• HLA-Cw*04 allele associated with nevirapine-induced rash in HIV-infected Thai patients.

  AIDS research and therapy 20090101

• Model and experiences of initiating collaboration with traditional healers in validation of ethnomedicines for HIV/AIDS in Namibia.

  Journal of ethnobiology and ethnomedicine 20090101

• Five-year follow up of genotypic resistance patterns in HIV-1 subtype C infected patients in Botswana after failure of thymidine analogue-based regimens.

  Journal of the International AIDS Society 20090101

• Inferring within-patient HIV-1 evolutionary dynamics under anti-HIV therapy using serial virus samples with vSPA.

  BMC bioinformatics 20090101

• In vivo evidence that truncated trkB.T1 participates in nociception.

  Molecular pain 20090101

• Oxidative imbalance in HIV-1 infected patients treated with antiretroviral therapy.

  Journal of biomedicine & biotechnology 20090101

• The cost effectiveness of home-based provision of antiretroviral therapy in rural Uganda.

  Applied health economics and health policy 20090101

• The prognosis of late presenters in the era of highly active antiretroviral therapy in serbia.

  The open virology journal 20090101

• Placental malaria among HIV-infected and uninfected women receiving anti-folates in a high transmission area of Uganda.

  Malaria journal 20090101

• Acceptability and effectiveness of chickpea sesame-based ready-to-use therapeutic food in malnourished HIV-positive adults.

  Patient preference and adherence 20090101

• Safety and tolerability of artemether-lumefantrine versus dihydroartemisinin-piperaquine for malaria in young HIV-infected and uninfected children.

  Malaria journal 20090101

• German-Austrian recommendations for HIV1-therapy in pregnancy and in HIV1-exposed newborn, update 2008.

  European journal of medical research 20090101

• Two standards of care for HIV: why are Africans being short-changed?

  Retrovirology 20090101

• Comparison of nucleoside reverse transcriptase inhibitor use as part of first-line therapy in a Serbian and a UK HIV clinic.

  HIV clinical trials 20090101

• Bioequivalence evaluation of a fixed dose combination lamivudine + stavudine tablet with concurrent administration of lamivudine tablet and stavudine capsule in healthy volunteers.

  Arzneimittel-Forschung 20090101

• Combination antiretroviral drugs in PLGA nanoparticle for HIV-1.

  BMC infectious diseases 20090101

• Hepatic profile analyses of tipranavir in Phase II and III clinical trials.

  BMC infectious diseases 20090101

• Early severe morbidity and resource utilization in South African adults on antiretroviral therapy.

  BMC infectious diseases 20090101

• Long term outcomes of antiretroviral therapy in a large HIV/AIDS care clinic in urban South Africa: a prospective cohort study.

  Journal of the International AIDS Society 20090101

• Treatment outcomes and plasma level of ritonavir-boosted lopinavir monotherapy among HIV-infected patients who had NRTI and NNRTI failure.

  AIDS research and therapy 20090101

• Optimal cytoplasmic transport in viral infections.

  PloS one 20090101

• Correlations between atazanavir C(trough )and hyperbilirubinemia: a case report.

  Journal of medical case reports 20090101

• Efficacy of first-line, WHO recommended generic HAART regimens in Indian children.

  Kathmandu University medical journal (KUMJ) 20090101

• Disfiguring molluscum contagiosum in a HIV-positive patient responding to antiretroviral therapy.

  Indian journal of dermatology 20090101

• Zidovudine induced pure red cell aplasia: a case report.

  Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria 20090101

• Kinetics and determining factors of the virologic response to antiretrovirals during pregnancy.

  Infectious diseases in obstetrics and gynecology 20090101

• Virologic suppression, treatment adherence, and improved quality of life on a once-daily efavirenz-based regimen in treatment-Naïve HIV-1-infected patients over 96 weeks.

  HIV clinical trials 20090101

• Resistance and virological response analyses in a three initial treatment strategy trial: a substudy of the INITIO trial.

  HIV clinical trials 20090101

• A Rough Set-Based Model of HIV-1 Reverse Transcriptase Resistome.

  Bioinformatics and biology insights 20090101

• Flail arm-like syndrome associated with HIV-1 infection.

  Annals of Indian Academy of Neurology 20090101

• The treatment of chronic hepatitis C virus infection in HIV co-infection.

  European journal of medical research 20090101

• Long-term efficacy and safety of once-daily nevirapine in combination with tenofovir and emtricitabine in the treatment of HIV-infected patients: a 72-week prospective multicenter study (TENOR-trial).

  European journal of medical research 20090101

• A young nonsmoker male patient with breathlessness.

  Lung India : official organ of Indian Chest Society 20090101

• Prevalence of Pain in Patients with HIV/AIDS: A Cross-sectional Survey in a South Indian State.

  Indian journal of palliative care 20090101

• Cardiovascular, renal and liver events associated with human immunodeficiency virus type 1 infection and antiretroviral therapy.

  F1000 medicine reports 20090101

• Treatment, care and support for people co-infected with HIV and hepatitis C: a scoping review.

  Open medicine : a peer-reviewed, independent, open-access journal 20090101

• New approaches in the management of chronic hepatitis B: role of tenofovir.

  Infection and drug resistance 20090101

• Progressive varicella syndrome in the setting of pediatric AIDS: An eye opener.

  Indian journal of sexually transmitted diseases and AIDS 20090101

• Papular pruritic eruptions: A marker of progressive HIV disease in children: Experience from eastern India.

  Indian journal of sexually transmitted diseases and AIDS 20090101

• Pharmacologic and nonpharmacologic options for the management of HIV infection during pregnancy.

  HIV/AIDS (Auckland, N.Z.) 20090101

• 5-(1-Acetoxyvinyl)-cycloSaligenyl-2',3'-dideoxy-2',3'- didehydrothymidine monophosphates, a second type of new, enzymatically activated cycloSaligenyl pronucleotides.

  Journal of medicinal chemistry 20081225

• Improved measures of quality of life, lipid profile, and lipoatrophy after treatment interruption in HIV-infected patients with immune preservation: results of ACTG 5170.

  Journal of acquired immune deficiency syndromes (1999) 20081201

• Toxicities associated with dual nucleoside reverse-transcriptase inhibitor regimens in HIV-infected children.

  The Journal of infectious diseases 20081201

• Antiretroviral therapy exposure and insulin resistance in the Women's Interagency HIV study.

  Journal of acquired immune deficiency syndromes (1999) 20081201

• [Clinical safety of a generic fixed-dose combination of stavudine/lamivudine/névirapine (Triomune). Study of 297 cases in Togo].

  Bulletin de la Societe de pathologie exotique (1990) 20081201

• Effect of highly active antiretroviral therapy on CD4 count and weight in AIDS patients seen at the UITH, Ilorin.

  Nigerian journal of clinical practice 20081201

• Early antiretroviral therapy and mortality among HIV-infected infants.

  The New England journal of medicine 20081120

• Studies on enzyme-cleavable dialkoxymethyl-cyclosaligenyl-2',3'-dideoxy-2',3'-didehydrothymidine monophosphates.

  Journal of medicinal chemistry 20081113

• Risk factors for mortality in symptomatic hyperlactatemia among HIV-infected patients receiving antiretroviral therapy in a resource-limited setting.

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20081101

• The discovery of antiviral agents: ten different compounds, ten different stories.

  Medicinal research reviews 20081101

• Changes in antioxidant profile among HIV-infected individuals on generic highly active antiretroviral therapy in southern India.

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20081101

• Steady-state pharmacokinetic comparison of generic and branded formulations of stavudine, lamivudine and nevirapine in HIV-infected Ugandan adults.

  The Journal of antimicrobial chemotherapy 20081101

• Bacillus Calmette-Guérin (BCG) vaccine-induced complications in children treated with highly active antiretroviral therapy.

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20081101

• Two-year outcomes of children on non-nucleoside reverse transcriptase inhibitor and protease inhibitor regimens in a South African pediatric antiretroviral program.

  The Pediatric infectious disease journal 20081101

• Safety and efficacy of initiating highly active antiretroviral therapy in an integrated antenatal and HIV clinic in Johannesburg, South Africa.

  Journal of acquired immune deficiency syndromes (1999) 20081101

• Gestational diabetes mellitus in a cohort of HIV-1 infected women.

  HIV medicine 20081101

• Intracellular trapping of cycloSal-pronucleotides: modification of prodrugs with amino acid esters.

  Journal of medicinal chemistry 20081023

• The 3-year renal safety of a tenofovir disoproxil fumarate vs. a thymidine analogue-containing regimen in antiretroviral-naive patients.

  AIDS (London, England) 20081018

• Synthesis of nucleoside-based antiviral drugs in ionic liquids.

  Bioorganic & medicinal chemistry letters 20081015

• Trends in the prescription of antiretroviral drugs and impact on plasma HIV-RNA measurements.

  The Journal of antimicrobial chemotherapy 20081001

• Recovery of fat following a switch to nucleoside reverse transcriptase inhibitor-sparing therapy in patients with lipoatrophy: results from the 96-week randomized ANRS 108 NoNuke Trial.

  HIV medicine 20081001

• Effect of haematological alterations on thalassaemia investigation in HIV-1-infected Thai patients receiving antiretroviral therapy.

  HIV medicine 20081001

• Secure antiretroviral therapy delivery in a resource-limited setting: streamlined to minimize drug resistance and expense.

  HIV medicine 20081001

• Viral efficacy maintained and safety parameters improved with a reduced dose of stavudine: a pilot study.

  HIV medicine 20081001

• Impact of long-term treatment with neurotoxic dideoxynucleoside antiretrovirals: implications for clinical care in resource-limited settings.

  HIV medicine 20081001

• Studies on antiretroviral drug concentrations in breast milk: validation of a liquid chromatography-tandem mass spectrometric method for the determination of 7 anti-human immunodeficiency virus medications.

  Therapeutic drug monitoring 20081001

• Foscarnet salvage therapy efficacy is associated with the presence of thymidine-associated mutations (TAMs) in HIV-infected patients.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20081001

• Increased regimen durability in the era of once-daily fixed-dose combination antiretroviral therapy.

  AIDS (London, England) 20081001

• Can we predict neuropathy risk before stavudine prescription in a resource-limited setting?

  AIDS research and human retroviruses 20081001

• Impact of human immunodeficiency virus type 1 reverse transcriptase inhibitor drug resistance mutation interactions on phenotypic susceptibility.

  AIDS research and human retroviruses 20081001

• Lopinavir/ritonavir in the treatment of HIV-1 infection: a review.

  Therapeutics and clinical risk management 20081001

• Simultaneous determination of endogenous deoxynucleotides and phosphorylated nucleoside reverse transcriptase inhibitors in peripheral blood mononuclear cells using ion-pair liquid chromatography coupled to mass spectrometry.

  Proteomics. Clinical applications 20081001

• Miscellaneous.

  Indian journal of pharmacology 20081001

• Disease- and treatment-related predictors of hepatic mitochondrial dysfunction in chronic HIV infection assessed by non-invasive (13)C-methionine breath test diagnostic.

  European journal of medical research 20080922

• A 39-year-old man with HIV-associated lipodystrophy.

  JAMA 20080903

• Validation of the Accutrend lactate meter for hyperlactatemia screening during antiretroviral therapy in a resource-poor setting.

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20080901

• A survey of the syntheses of active pharmaceutical ingredients for antiretroviral drug combinations critical to access in emerging nations.

  Antiviral research 20080901

• Evaluation of a systematic substitution of zidovudine for stavudine-based HAART in a program setting in rural Cambodia.

  Journal of acquired immune deficiency syndromes (1999) 20080901

• HIV infection in the elderly.

  Clinical interventions in aging 20080901

• Endothelial function in human immunodeficiency virus-infected antiretroviral-naive subjects before and after starting potent antiretroviral therapy: The ACTG (AIDS Clinical Trials Group) Study 5152s.

  Journal of the American College of Cardiology 20080812

• Triple antiretroviral therapy improves psoriasis associated with human immunodeficiency virus infection: a clinico-therapeutic experience.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20080801

• An HIV-1 215V mutant shows increased phenotypic resistance to d4T.

  Virus research 20080801

• Efavirenz replacement by immediate full-dose nevirapine is safe in HIV-1-infected patients in Cambodia.

  HIV medicine 20080801

• The nucleoside reverse transcriptase inhibitors didanosine, lamivudine, stavudine and zidovudine show little effect on the virulence of Candida albicans in vitro.

  International journal of antimicrobial agents 20080801

• Urogenital tuberculosis in a patient with AIDS: an unusual presentation.

  Nature clinical practice. Urology 20080801

• The A62V and S68G mutations in HIV-1 reverse transcriptase partially restore the replication defect associated with the K65R mutation.

  Journal of acquired immune deficiency syndromes (1999) 20080801

• Tenofovir: what have over 1 million years of patient experience taught us?

  International journal of clinical practice 20080801

• FDA notifications. Tentative approval granted for lamivudine/stavudine.

  AIDS alert 20080801

• Two cases of multidrug-resistant human immunodeficiency virus infection treated with atazanavir and lopinavir/ritonavir combination therapy.

  Journal of Korean medical science 20080801

• The Relationship Between HIV Infection and Cardiovascular Disease.

  Current cardiology reviews 20080801

• Fanconi syndrome and lactic acidosis associated with stavudine and lamivudine therapy.

  AIDS (London, England) 20080711

• The diagnostic criteria for small fibre neuropathy: from symptoms to neuropathology.

  Brain : a journal of neurology 20080701

• Cost and cost-effectiveness of switching from stavudine to tenofovir in first-line antiretroviral regimens in South Africa.

  Journal of acquired immune deficiency syndromes (1999) 20080701

• Prevalence and predictors of metabolic syndrome among HIV-infected and HIV-uninfected women in the Women's Interagency HIV Study.

  Journal of acquired immune deficiency syndromes (1999) 20080701

• Prevalence of infection with hepatitis B and C virus and coinfection with HIV in medical inpatients in Malawi.

  The Journal of infection 20080701

• Neurologic disorders are prevalent in HIV-positive outpatients in the Asia-Pacific region.

  Neurology 20080701

• Public-health and individual approaches to antiretroviral therapy: township South Africa and Switzerland compared.

  PLoS medicine 20080701

• Outlook on Thailand's genomics and computational biology research and development.

  PLoS computational biology 20080701

• Durability and outcome of initial antiretroviral treatments received during 2000--2005 by patients in the Swiss HIV Cohort Study.

  The Journal of infectious diseases 20080615

• [Drug-related neuropathies: analysis of the French Adverse Drug Reaction Database 1995-2005].

  Presse medicale (Paris, France : 1983) 20080601

• Incidence and risk factors for new-onset diabetes in HIV-infected patients: the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study.

  Diabetes care 20080601

• High concentrations of stavudine impair fatty acid oxidation without depleting mitochondrial DNA in cultured rat hepatocytes.

  Toxicology in vitro : an international journal published in association with BIBRA 20080601

• Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/lamivudine--a Staccato trial substudy.

  The Journal of antimicrobial chemotherapy 20080601

• A review of current intravaginal drug delivery approaches employed for the prophylaxis of HIV/AIDS and prevention of sexually transmitted infections.

  AAPS PharmSciTech 20080601

• Sensitive and rapid titrimetric and spectrophotometric methods for the determination of stavudine in pharmaceuticals using bromate-bromide and three dyes.

  Anais da Academia Brasileira de Ciencias 20080601

• Adherence to antiretroviral therapy assessed by drug level monitoring and self-report in cameroon.

  Journal of acquired immune deficiency syndromes (1999) 20080601

• Atriplatrade mark - HIV therapy in one pill.

  Therapeutics and clinical risk management 20080601

• [Tenofovir as a strategy to avoid or limit adverse effects].

  Enfermedades infecciosas y microbiologia clinica 20080601

• Is it safe to switch from stavudine to zidovudine after developing symptomatic hyperlactatemia?

  African health sciences 20080601

• Stability of antiretroviral regimens in patients with viral suppression.

  AIDS (London, England) 20080531

• Highly active antiretroviral HIV therapy-associated fatal lactic acidosis: quantitative and qualitative mitochondrial DNA lesions with mitochondrial dysfunction in multiple organs.

  AIDS (London, England) 20080531

• Population-level effect of HIV on adult mortality and early evidence of reversal after introduction of antiretroviral therapy in Malawi.

  Lancet (London, England) 20080510

• Longitudinal effects of thymidine analogues on mtDNA, mtRNA and multidrug resistance (MDR-1) induction in cultured cells.

  The Journal of antimicrobial chemotherapy 20080501

• Haematological changes after switching from stavudine to zidovudine in HIV-infected children receiving highly active antiretroviral therapy.

  HIV medicine 20080501

• Drug-specific effect of nelfinavir and stavudine on primary culture of human preadipocytes.

  Journal of acquired immune deficiency syndromes (1999) 20080501

• Determination of clinically relevant cutoffs for HIV-1 phenotypic resistance estimates through a combined analysis of clinical trial and cohort data.

  Journal of acquired immune deficiency syndromes (1999) 20080501

• Antiretroviral drug resistance among antiretroviral-naïve persons with recent HIV infection in Thailand.

  HIV medicine 20080501

• Subclinic atherosclerosis and cardiovascular risk factors in HIV-infected children: PERI study.

  Coronary artery disease 20080501

• Safety of stavudine in the treatment of HIV infection with a special focus on resource-limited settings.

  Expert opinion on drug safety 20080501

• Long-term subcutaneous tissue changes among antiretroviral-naive persons initiating stavudine, zidovudine, or abacavir with lamivudine.

  Journal of acquired immune deficiency syndromes (1999) 20080501

• Pharmacy refill adherence compared with CD4 count changes for monitoring HIV-infected adults on antiretroviral therapy.

  PLoS medicine 20080501

• Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaboration.

  Lancet (London, England) 20080426

• Outcomes from monitoring of patients on antiretroviral therapy in resource-limited settings with viral load, CD4 cell count, or clinical observation alone: a computer simulation model.

  Lancet (London, England) 20080426

• Effect of reducing the dose of stavudine on body composition, bone density, and markers of mitochondrial toxicity in HIV-infected subjects: a randomized, controlled study.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080415

• The effect of reducing the dose of stavudine on body composition, bone density, and markers of mitochondrial toxicity in HIV-infected subjects: answers and questions.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080415

• Stavudine plasma concentrations and lipoatrophy.

  The Journal of antimicrobial chemotherapy 20080401

• Prevalence and risk factors for developing K65R mutations among HIV-1 infected patients who fail an initial regimen of fixed-dose combination of stavudine, lamivudine, and nevirapine.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20080401

• Quantification of seven nucleoside/nucleotide reverse transcriptase inhibitors in human plasma by high-performance liquid chromatography with tandem mass-spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080401

• Long-term safety and efficacy results of once-daily emtricitabine-based highly active antiretroviral therapy regimens in human immunodeficiency virus-infected pediatric subjects.

  Pediatrics 20080401

• A novel probe drug interaction study to investigate the effect of selected antiretroviral combinations on the pharmacokinetics of a single oral dose of maraviroc in HIV-positive subjects.

  British journal of clinical pharmacology 20080401

• Nevirapine-induced Stevens-Johnson syndrome in an HIV patient.

  Cornea 20080401

• Spectrum of adverse events after generic HAART in southern Indian HIV-infected patients.

  AIDS patient care and STDs 20080401

• [AIDS: ethics and scientific investigation on human beings].

  Bulletin de la Societe de pathologie exotique (1990) 20080401

• [Evaluation of antiretroviral therapy in HIV-infected adults in the Department of Haematology, University Hospital of Brazzavllle, Congo].

  Bulletin de la Societe de pathologie exotique (1990) 20080401

• FDA notifications. Generic stavudine and efavirenz are tentatively approved by FDA.

  AIDS alert 20080401

• Nevirapine, stavudine and lamivudine pharmacokinetics in African children on paediatric fixed-dose combination tablets.

  AIDS (London, England) 20080312

• Radiolabeling, pharmacoscintigraphic evaluation and antiretroviral efficacy of stavudine loaded 99mTc labeled galactosylated liposomes.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080303

• Lipodystrophy and weight changes: data from the Swiss HIV Cohort Study, 2000-2006.

  HIV medicine 20080301

• Progression of fibrosis in HIV and hepatitis C virus-coinfected patients treated with interferon plus ribavirin-based therapy: analysis of risk factors.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080301

• Determination of abacavir, amprenavir, didanosine, efavirenz, nevirapine, and stavudine concentration in human plasma by MALDI-TOF/TOF.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080301

• Pyrimidine nucleoside depletion sensitizes to the mitochondrial hepatotoxicity of the reverse transcriptase inhibitor stavudine.

  The American journal of pathology 20080301

• Mortality in HIV-infected Ugandan adults receiving antiretroviral treatment and survival of their HIV-uninfected children: a prospective cohort study.

  Lancet (London, England) 20080301

• Tolerability and effectiveness of first-line regimens combining nevirapine and lamivudine plus zidovudine or stavudine in Cameroon.

  AIDS research and human retroviruses 20080301

• Emergence of an NNRTI resistance mutation Y181C in an HIV-infected NNRTI-naive patient.

  AIDS research and human retroviruses 20080301

• IL-1beta (+3954C/T) polymorphism could protect human immunodeficiency virus (HIV)-infected patients on highly active antiretroviral treatment (HAART) against lipodystrophic syndrome.

  Genetics in medicine : official journal of the American College of Medical Genetics 20080301

• Changes in lipid profile over 24 months among adults on first-line highly active antiretroviral therapy in the home-based AIDS care program in rural Uganda.

  Journal of acquired immune deficiency syndromes (1999) 20080301

• Maternal 12-month response to antiretroviral therapy following prevention of mother-to-child transmission of HIV type 1, Ivory Coast, 2003-2006.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080215

• Efficacy and safety of atazanavir, with or without ritonavir, as part of once-daily highly active antiretroviral therapy regimens in antiretroviral-naive patients.

  Journal of acquired immune deficiency syndromes (1999) 20080201

• Design and profiling of GS-9148, a novel nucleotide analog active against nucleoside-resistant variants of human immunodeficiency virus type 1, and its orally bioavailable phosphonoamidate prodrug, GS-9131.

  Antimicrobial agents and chemotherapy 20080201

• Association of APOC3 polymorphisms with both dyslipidemia and lipoatrophy in HAART-receiving patients.

  AIDS research and human retroviruses 20080201

• Cytokine genotype suggests a role for inflammation in nucleoside analog-associated sensory neuropathy (NRTI-SN) and predicts an individual's NRTI-SN risk.

  AIDS research and human retroviruses 20080201

• Microbicides for multidrug-resistant and multitropic HIV-1.

  Current opinion in investigational drugs (London, England : 2000) 20080201

• A ten-year analysis of the incidence and risk factors for acute pancreatitis requiring hospitalization in an urban HIV clinical cohort.

  AIDS patient care and STDs 20080201

• HIV infection and the pancreas: risk factors and potential management guidelines.

  International journal of STD & AIDS 20080201

• [Polyneuropathies in patients treated with HAART in Bobo-Dioulasso hospital, Burkina Faso].

  Bulletin de la Societe de pathologie exotique (1990) 20080201

• The role of antiretroviral therapy in the incidence of pancreatitis in HIV-positive individuals in the EuroSIDA study.

  AIDS (London, England) 20080102

• Incidence of pancreatitis in HIV-infected patients: comment on findings in EuroSIDA cohort.

  AIDS (London, England) 20080102

• The prevalence and risk of hepatitis flares in a Serbian cohort of HIV and HCV co-infected patients treated with HAART.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080101

• Relationship of fat distribution with adipokines in human immunodeficiency virus infection.

  The Journal of clinical endocrinology and metabolism 20080101

• Human immunodeficiency virus types 1 and 2 exhibit comparable sensitivities to Zidovudine and other nucleoside analog inhibitors in vitro.

  Antimicrobial agents and chemotherapy 20080101

• Long-distance interactive expert advice in highly treatment-experienced HIV-infected patients.

  The Journal of antimicrobial chemotherapy 20080101

• Treatment options for lipodystrophy in HIV-positive patients.

  Expert opinion on pharmacotherapy 20080101

• Antiretroviral therapy : optimal sequencing of therapy to avoid resistance.

  Drugs 20080101

• Effects of the change from Stavudine to tenofovir in human immunodeficiency virus-infected children treated with highly active antiretroviral therapy: studies on mitochondrial toxicity and thymic function.

  The Pediatric infectious disease journal 20080101

• Extensive hypopigmentation after starting antiretroviral treatment in an human immunodeficiency virus (HIV)-seropositive African woman.

  International journal of dermatology 20080101

• Antiretroviral therapy in the Malawi defence force: access, treatment outcomes and impact on mortality.

  PloS one 20080101

• Seven-year efficacy of a lopinavir/ritonavir-based regimen in antiretroviral-naïve HIV-1-infected patients.

  HIV clinical trials 20080101

• The incidence of multidrug and full class resistance in HIV-1 infected patients is decreasing over time (2001-2006) in Portugal.

  Retrovirology 20080101

• Socioeconomic status (SES) as a determinant of adherence to treatment in HIV infected patients: a systematic review of the literature.

  Retrovirology 20080101

• Nucleoside analogue reverse transcriptase inhibitors differentially inhibit human LINE-1 retrotransposition.

  PloS one 20080101

• Identification of a novel resistance (E40F) and compensatory (K43E) substitution in HIV-1 reverse transcriptase.

  Retrovirology 20080101

• Twenty-four-week safety and tolerability of nevirapine vs. abacavir in combination with zidovudine/lamivudine as first-line antiretroviral therapy: a randomized double-blind trial (NORA).

  Tropical medicine & international health : TM & IH 20080101

• Adaptation of antiretroviral therapy in human immunodeficiency virus infection with central nervous system involvement.

  Journal of neurovirology 20080101

• Dangerous medicines: unproven AIDS cures and counterfeit antiretroviral drugs.

  Globalization and health 20080101

• Transmitted drug resistance, selection of resistance mutations and moderate antiretroviral efficacy in HIV-2: analysis of the HIV-2 Belgium and Luxembourg database.

  BMC infectious diseases 20080101

• Longitudinal microarray analysis of cell surface antigens on peripheral blood mononuclear cells from HIV+ individuals on highly active antiretroviral therapy.

  Retrovirology 20080101

• Computed CD4 percentage as a low-cost method for determining pediatric antiretroviral treatment eligibility.

  BMC infectious diseases 20080101

• Bullous eruption in a patient infected with the human immunodeficiency virus.

  Skinmed 20080101

• High grade B-cell gastric lymphoma with complete pathologic remission after eradication of Helicobacter pylori infection: report of a case and review of the literature.

  World journal of surgical oncology 20080101

• Vascularization of the dorsal root ganglia and peripheral nerve of the mouse: implications for chemical-induced peripheral sensory neuropathies.

  Molecular pain 20080101

• Mechanism of HIV protein induced modulation of mesenchymal stem cell osteogenic differentiation.

  BMC musculoskeletal disorders 20080101

• Fosamprenavir or atazanavir once daily boosted with ritonavir 100 mg, plus tenofovir/emtricitabine, for the initial treatment of HIV infection: 48-week results of ALERT.

  AIDS research and therapy 20080101

• Contribution of mitochondrial dysfunction and oxidative stress to cellular premature senescence induced by antiretroviral thymidine analogues.

  Antiviral therapy 20080101

• Effect of pioglitazone on HIV-1-related lipodystrophy: a randomized double-blind placebo-controlled trial (ANRS 113).

  Antiviral therapy 20080101

• Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso.

  Antiviral therapy 20080101

• Predictors of mortality in HIV-infected patients starting antiretroviral therapy in a rural hospital in Tanzania.

  BMC infectious diseases 20080101

• Streamlining tasks and roles to expand treatment and care for HIV: randomised controlled trial protocol.

  Trials 20080101

• Stavudine-induced pancreatitis followed by lopinavir-ritonavir-induced pancreatitis.

  Journal of postgraduate medicine 20080101

• Prevalence, genotypic associations and phenotypic characterization of K65R, L74V and other HIV-1 RT resistance mutations in a commercial database.

  Antiviral therapy 20080101

• Prevalence of dyslipidemia and dysglycaemia in HIV infected patients.

  East African medical journal 20080101

• Randomization to once-daily stavudine extended release/lamivudine/efavirenz versus a more frequent regimen improves adherence while maintaining viral suppression.

  HIV clinical trials 20080101

• Prevalence of reverse transcriptase and protease mutations associated with antiretroviral drug resistance among drug-naïve HIV-1 infected pregnant women in Kagera and Kilimanjaro regions, Tanzania.

  AIDS research and therapy 20080101

• Long-term efficacy and safety of first-line therapy with once-daily saquinavir/ritonavir.

  Antiviral therapy 20080101

• HIV drug resistance transmission threshold survey in Bangkok, Thailand.

  Antiviral therapy 20080101

• Adverse effects of antiretroviral treatment.

  Indian journal of dermatology, venereology and leprology 20080101

• Stavudine-induced pancreatitis followed by lopinavir-ritonavir-induced pancreatitis: is co-trimoxazole the culprit?

  Journal of postgraduate medicine 20080101

• Risk factors for poor virological outcome at 12 months in a workplace-based antiretroviral therapy programme in South Africa: a cohort study.

  BMC infectious diseases 20080101

• Childhood TB epidemiology and treatment outcomes in Thailand: a TB active surveillance network, 2004 to 2006.

  BMC infectious diseases 20080101

• Viral hepatitis and HIV-associated tuberculosis: risk factors and TB treatment outcomes in Thailand.

  BMC public health 20080101

• CCR5Delta32 genotypes in a German HIV-1 seroconverter cohort and report of HIV-1 infection in a CCR5Delta32 homozygous individual.

  PloS one 20080101

• Coprocessing of nevirapine and stavudine by spray drying.

  Pharmaceutical development and technology 20080101

• Species distribution and in vitro antifungal susceptibility of oral yeast isolates from Tanzanian HIV-infected patients with primary and recurrent oropharyngeal candidiasis.

  BMC microbiology 20080101

• Hepatic steatosis in patients with HIV-Hepatitis C Virus coinfection: is it associated with antiretroviral therapy and more advanced hepatic fibrosis?

  BMC research notes 20080101

• A color Doppler ultrasound-based comparative study between stavudine and non-stavudine regimens in the onset of vascular lesions in HIV-1-positive patients.

  In vivo (Athens, Greece) 20080101

• Impaired expression of mitochondrial and adipogenic genes in adipose tissue from a patient with acquired partial lipodystrophy (Barraquer-Simons syndrome): a case report.

  Journal of medical case reports 20080101

• Adherence to antiretroviral therapy in young children in Cape Town, South Africa, measured by medication return and caregiver self-report: a prospective cohort study.

  BMC pediatrics 20080101

• The levator aponeurosis exposed.

  Ophthalmic plastic and reconstructive surgery 20080101

• beta-Estradiol attenuates the anti-HIV-1 efficacy of Stavudine (D4T) in primary PBL.

  Retrovirology 20080101

• [Outcome of HIV-infected patients of peritoneal dialysis: experience in a center and literature review].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20080101

• Resting regulatory CD4 T cells: a site of HIV persistence in patients on long-term effective antiretroviral therapy.

  PloS one 20080101

• Success with antiretroviral treatment for children in Kigali, Rwanda: experience with health center/nurse-based care.

  BMC pediatrics 20080101

• Pathogenesis and treatment of lipodystrophy: what clinicians need to know.

  Topics in HIV medicine : a publication of the International AIDS Society, USA 20080101

• Durability of stavudine, lamivudine and nevirapine among advanced HIV-1 infected patients with/without prior co-administration of rifampicin: a 144-week prospective study.

  BMC infectious diseases 20080101

• Dyslipidemia and cardiovascular disease risk factor management in HIV-1-infected subjects treated with HAART in the Spanish VACH cohort.

  The open AIDS journal 20080101

• Pharmacokinetics of acetyl-L-carnitine given in single or multiple doses to HIV-1 Infected patients with toxic peripheral polyneuropathy.

  The open AIDS journal 20080101

• Outcome of protease inhibitor substitution with nevirapine in HIV-1 infected children.

  BMC infectious diseases 20080101

• A feasibility study of immediate versus deferred antiretroviral therapy in children with HIV infection.

  AIDS research and therapy 20080101

• The influence of lamivudine, stavudine and nevirapine on the pharmacokinetics of chlorpropamide in human subjects.

  European journal of drug metabolism and pharmacokinetics 20080101

• Immune reconstitution inflammatory syndrome manifesting as disseminated tuberculosis, deep venous thrombosis, encephalopathy and myelopathy.

  The Indian journal of chest diseases & allied sciences 20080101

• Severe hyperlactataemia complicating stavudine first-line antiretroviral therapy in South Africa.

  Antiviral therapy 20080101

• Human immunodeficiency virus seroconversion presenting with acute inflammatory demyelinating polyneuropathy: a case report.

  Journal of medical case reports 20080101

• Adherence to highly active antiretroviral therapy and its correlates among HIV infected pediatric patients in Ethiopia.

  BMC pediatrics 20080101

• EBV-Associated Smooth Muscle Neoplasms: Solid Tumors Arising in the Presence of Immunosuppression and Autoimmune Diseases.

  Sarcoma 20080101

• Three generic nevirapine-based antiretroviral treatments in Chinese HIV/AIDS patients: multicentric observation cohort.

  PloS one 20080101

• Intranasal administration of acetylcholinesterase inhibitors.

  BMC neuroscience 20080101

• Steady state bioequivalence of generic and innovator formulations of stavudine, lamivudine, and nevirapine in HIV-infected Ugandan adults.

  PloS one 20080101

• HIV coinfection and antiretroviral therapy enhances liver steatosis in patients with hepatitis C, but only in those infected by HCV genotype other than 3.

  Antiviral therapy 20080101

• Objective assessment of facial lipoatrophy changes in a cohort of HIV-infected patients taking combination antiretroviral therapy.

  HIV clinical trials 20080101

• Improvements in subcutaneous fat, lipid profile, and parameters of mitochondrial toxicity in patients with peripheral lipoatrophy when stavudine is switched to tenofovir (LIPOTEST study).

  HIV clinical trials 20080101

• High treatment success rates when switching to once daily nevirapine containing antiretroviral therapy.

  The open AIDS journal 20080101

• Harnessing pharmacogenomics to tackle resistance to the 'nucleoside reverse trancripatse inhibitor' backbone of highly active antiretroviral therapy in resource limited settings.

  The open AIDS journal 20080101

• Steatohepatitis due to antiretroviral therapy.

  The West Indian medical journal 20080101

• Effectiveness and Safety of Generic Fixed-Dose Combination of Tenofovir/Emtricitabine/Efavirenz in HIV-1-Infected Patients in Western India.

  Journal of the International AIDS Society 20080101

• Solid-state characterization of nevirapine.

  Indian journal of pharmaceutical sciences 20080101

• Determinants of retention in care in an antiretroviral therapy (ART) program in urban Cameroon, 2003-2005.

  The Pan African medical journal 20080101

• Chinese pediatric highly active antiretroviral therapy observational cohort: a 1-year analysis of clinical, immunologic, and virologic outcomes.

  Journal of acquired immune deficiency syndromes (1999) 20071215

• [HIV-1 genotypic resistance profiles in children failing highly active antiretroviral therapy].

  Zhonghua yi xue za zhi 20071211

• Oral administration of stavudine induces hyperalgesia without affecting activity in rats.

  Physiology & behavior 20071205

• Adherence to HAART therapy measured by electronic monitoring in newly diagnosed HIV patients in Botswana.

  European journal of clinical pharmacology 20071201

• Influence of concomitant antiretroviral therapy on the rate of sustained virological response to pegylated interferon plus ribavirin in hepatitis C virus/HIV-coinfected patients.

  The Journal of antimicrobial chemotherapy 20071201

• N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance.

  PLoS medicine 20071201

• Should we include connection domain mutations of HIV-1 reverse transcriptase in HIV resistance testing.

  PLoS medicine 20071201

• Metabolic function and the prevalence of lipodystrophy in a population of HIV-infected African subjects receiving highly active antiretroviral therapy.

  Journal of acquired immune deficiency syndromes (1999) 20071201

• An efficient tool for surveying CRF01_AE HIV type 1 resistance in Thailand to combined stavudine-lamivudine-nevirapine treatment: mutagenically separated PCR targeting M184I/V.

  AIDS research and human retroviruses 20071201

• Characterization of HIV-1 subtypes and viral antiretroviral drug resistance in men who have sex with men in Beijing, China.

  AIDS (London, England) 20071201

• Antiretroviral therapy-associated toxicities in the resource-poor world: the challenge of a limited formulary.

  The Journal of infectious diseases 20071201

• A single-dose, randomized, open-label, two-period crossover bioequivalence study of a fixed-dose pediatric combination of lamivudine 40-mg, nevirapine 70-mg, and stavudine 10-mg tablet for oral suspension with individual liquid formulations in healthy adult male volunteers.

  Clinical therapeutics 20071201

• FDA notifications. Tentative approval for generic stavudine, oral solution.

  AIDS alert 20071201

• Review of tenofovir-emtricitabine.

  Therapeutics and clinical risk management 20071201

• Risk factors for lactic acidosis and severe hyperlactataemia in HIV-1-infected adults exposed to antiretroviral therapy.

  AIDS (London, England) 20071130

• [Evaluation for two-year highly active antiretroviral therapy in Chinese HIV-1 infection patients].

  Zhonghua yi xue za zhi 20071113

• Positive outcomes of HAART at 24 months in HIV-infected patients in Cambodia.

  AIDS (London, England) 20071112

• HIV drug resistance after the use of generic fixed-dose combination stavudine/lamivudine/nevirapine as standard first-line regimen.

  AIDS (London, England) 20071112

• NNRTI-selected mutations at codon 190 of human immunodeficiency virus type 1 reverse transcriptase decrease susceptibility to stavudine and zidovudine.

  Antiviral research 20071101

• Population pharmacokinetic analysis of lamivudine, stavudine and zidovudine in controlled HIV-infected patients on HAART.

  European journal of clinical pharmacology 20071101

• From docking false-positive to active anti-HIV agent.

  Journal of medicinal chemistry 20071101

• Effectiveness of highly active antiretroviral therapy in HIV-positive children: evaluation at 12 months in a routine program in Cambodia.

  Pediatrics 20071101

• Evolution of antiretroviral drug costs in Brazil in the context of free and universal access to AIDS treatment.

  PLoS medicine 20071101

• Liver enzymes elevation and immune reconstitution among treatment-naïve HIV-infected patients instituting antiretroviral therapy.

  The American journal of the medical sciences 20071101

• Cryptococcal meningoradiculitis: an atypical presentation after initiation of antiretroviral therapy.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20071101

• HIV antiretroviral medications and hepatotoxicity.

  Current opinion in HIV and AIDS 20071101

• Management and therapy of chronic hepatitis C in HIV.

  Current opinion in HIV and AIDS 20071101

• Differential sensitivity of thick and thin fibers to HIV and therapy-induced neuropathy.

  Autonomic neuroscience : basic & clinical 20071030

• Clinical outcomes and CD4 cell response in children receiving antiretroviral therapy at primary health care facilities in Zambia.

  JAMA 20071024

• The excision mechanism in reverse transcriptase: pyrophosphate leaving and fingers opening are uncoupled events with the analogues AZT and d4T.

  The journal of physical chemistry. B 20071018

• Mucosal safety of PHI-443 and stampidine as a combination microbicide to prevent genital transmission of HIV-1.

  Fertility and sterility 20071001

• Simultaneous determination of 17 antiretroviral drugs in human plasma for quantitative analysis with liquid chromatography-tandem mass spectrometry.

  Biomedical chromatography : BMC 20071001

• Effects of apricitabine and other nucleoside reverse transcriptase inhibitors on replication of mitochondrial DNA in HepG2 cells.

  Antiviral research 20071001

• Predictors of long-term viral failure among ugandan children and adults treated with antiretroviral therapy.

  Journal of acquired immune deficiency syndromes (1999) 20071001

• Pharmacokinetics of coadministered ritonavir-boosted elvitegravir and zidovudine, didanosine, stavudine, or abacavir.

  Journal of acquired immune deficiency syndromes (1999) 20071001

• Polymorphism and drug selected mutations of reverse transcriptase gene in 102 HIV-1 infected patients living in China.

  Journal of medical virology 20071001

• Prior antiretroviral therapy experience protects against zidovudine-related anaemia.

  HIV medicine 20071001

• Tenofovir resistance among HIV-infected patients failing a fixed-dose combination of stavudine, lamivudine, and nevirapine in a resource-limited setting.

  AIDS patient care and STDs 20071001

• Health-related quality of life outcomes in HIV-infected patients starting different combination regimens in a randomized multinational trial: the INITIO-QoL substudy.

  AIDS research and human retroviruses 20071001

• Impact of the number of failed therapeutic regimes on the development of resistance mutations to HIV-1 in northeast Brazil.

  The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20071001

• Dandy-Walker variant in an infant prenatally exposed to antiretroviral medication.

  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20071001

• Synthesis and anti-HIV evaluation of hybrid-type prodrugs conjugating HIV integrase inhibitors with d4t by self-cleavable spacers containing an amino acid residue.

  Journal of enzyme inhibition and medicinal chemistry 20071001

• Prevalence of antiretroviral drug resistance in treated HIV-1 infected patients: under the initiative of access to the NNRTI-based regimen in Thailand.

  Journal of chemotherapy (Florence, Italy) 20071001

• [Efficacy and safety of a reduced-dose of stavudine in HIV-infected patients under immunological and virological stable conditions].

  Medicina clinica 20070922

• [Stavudine in antiretroviral therapy].

  Medicina clinica 20070922

• Antiretroviral drug dosing errors in HIV-infected patients undergoing hemodialysis.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070915

• Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis.

  AIDS (London, England) 20070912

• Anti-adenoviral effect of anti-HIV agents in vitro in serotypes inducing keratoconjunctivitis.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20070901

• Erythrocebus patas monkey offspring exposed perinatally to NRTIs sustain skeletal muscle mitochondrial compromise at birth and at 1 year of age.

  Toxicological sciences : an official journal of the Society of Toxicology 20070901

• Mutations at 65 and 70 within the context of a Q151M cluster in human immunodeficiency virus type 1 reverse transcriptase impact the susceptibility to the different nucleoside reverse transcriptase inhibitors in distinct ways.

  Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20070901

• Prevalence of and risk factors for HIV-associated neuropathy in Melbourne, Australia 1993-2006.

  HIV medicine 20070901

• Hepatotoxicity of antiretroviral drugs is reduced after successful treatment of chronic hepatitis C in HIV-infected patients.

  The Journal of infectious diseases 20070901

• Steatohepatitis in HIV-infected subjects: pathogenesis, clinical impact and implications in clinical management.

  Current HIV research 20070901

• In vivo interactive effect of garlic oil and vitamin E against stavudine induced genotoxicity in Mus musculus.

  Indian journal of experimental biology 20070901

• HIV-associated neuromuscular weakness syndrome in Brazil: report of the two first cases.

  Arquivos de neuro-psiquiatria 20070901

• Regression of a cervical spinal mass following highly active antiretroviral therapy (HAART) in child with advanced human immunodeficiency virus (HIV) disease.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20070901

• Children with HIV are not small adults: what is different in pharmacology?

  Current opinion in HIV and AIDS 20070901

• Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs.

  Bioorganic & medicinal chemistry 20070815

• Long-term body fat outcomes in antiretroviral-naive participants randomized to nelfinavir or efavirenz or both plus dual nucleosides. Dual X-ray absorptiometry results from A5005s, a substudy of Adult Clinical Trials Group 384.

  Journal of acquired immune deficiency syndromes (1999) 20070815

• Symptomatic hyperlactatemia associated with nucleoside analogue reverse-transcriptase inhibitor use in HIV-infected patients: a report of 24 cases in a resource-limited setting (Uganda).

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070815

• Reduced hepatic toxicity, enhanced cellular uptake and altered pharmacokinetics of stavudine loaded galactosylated liposomes.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070801

• Emergence of human immunodeficiency virus type 1 variants containing the Q151M complex in children receiving long-term antiretroviral chemotherapy.

  Antiviral research 20070801

• Transport of stavudine, delavirdine, and saquinavir across the blood-brain barrier by polybutylcyanoacrylate, methylmethacrylate-sulfopropylmethacrylate, and solid lipid nanoparticles.

  International journal of pharmaceutics 20070801

• Evolution of a novel 5-amino-acid insertion in the beta3-beta4 loop of HIV-1 reverse transcriptase.

  Virology 20070801

• High prevalence of lipoatrophy among patients on stavudine-containing first-line antiretroviral therapy regimens in Rwanda.

  Transactions of the Royal Society of Tropical Medicine and Hygiene 20070801

• Development of a highly efficient extraction technique and specific multiplex assay for measuring antiretroviral drug concentrations in breast milk.

  Therapeutic drug monitoring 20070801

• Antiretroviral treatment and prevention of peripartum and postnatal HIV transmission in West Africa: evaluation of a two-tiered approach.

  PLoS medicine 20070801

• Comparative bioavailability/bioequivalence of two different stavudine 40 mg capsule formulations: a randomized, 2-way, crossover study in healthy volunteers under fasting condition.

  International journal of clinical pharmacology and therapeutics 20070801

• Baseline genotype as a predictor of virological failure to emtricitabine or stavudine in combination with didanosine and efavirenz.

  AIDS research and human retroviruses 20070801

• Effect of processing temperature on Eudragit RS PO microsphere characteristics in the solvent evaporation process.

  Die Pharmazie 20070801

• The renaissance of fixed dose combinations: Combivir.

  Therapeutics and clinical risk management 20070801

• Review of tipranavir in the treatment of drug-resistant HIV.

  Therapeutics and clinical risk management 20070801

• Non-homologous recombination of deoxyribonucleoside kinases from human and Drosophila melanogaster yields human-like enzymes with novel activities.

  Journal of molecular biology 20070720

• A high incidence of lactic acidosis and symptomatic hyperlactatemia in women receiving highly active antiretroviral therapy in Soweto, South Africa.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070715

• Sex differences in antiretroviral therapy toxicity: lactic acidosis, stavudine, and women.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070715

• Age-related differences in the pharmacokinetics of stavudine in 272 children from birth to 16 years: a population analysis.

  British journal of clinical pharmacology 20070701

• Early response to highly active antiretroviral therapy in HIV-1-infected Kenyan children.

  Journal of acquired immune deficiency syndromes (1999) 20070701

• Antiretroviral durability and tolerability in HIV-infected adults living in urban Kenya.

  Journal of acquired immune deficiency syndromes (1999) 20070701

• Design, synthesis, and anti-HIV activity of 2',3'-didehydro-2',3'-dideoxyuridine (d4U), 2',3'-dideoxyuridine (ddU) phosphoramidate 'ProTide' derivatives.

  Bioorganic & medicinal chemistry letters 20070701

• Pharmacokinetic evaluation of emtricitabine in combination with other nucleoside antivirals in healthy volunteers.

  Journal of clinical pharmacology 20070701

• Effects of potent antiretroviral therapy on free testosterone levels and fat-free mass in men in a prospective, randomized trial: A5005s, a substudy of AIDS Clinical Trials Group Study 384.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070701

• Performance of a World Health Organization first-line regimen (stavudine/lamivudine/nevirapine) in antiretroviral-naïve individuals in a Western setting.

  HIV medicine 20070701

• A 21-base pair insertion/duplication at codon 69 of the HIV type 1 reverse transcriptase in a patient undergoing multiple nucleoside therapy.

  AIDS research and human retroviruses 20070701

• Fixed dose combination of lamivudine, stavudine and nevirapine in the treatment of pediatric HIV infection: a preliminary report.

  Indian pediatrics 20070701

• Alopecia induced by lopinavir plus ritonavir therapy in an HIV patient.

  Journal of drugs in dermatology : JDD 20070701

• Antiretroviral therapy during tuberculosis treatment and marked reduction in death rate of HIV-infected patients, Thailand.

  Emerging infectious diseases 20070701

• Hepatotoxicity and liver disease in the context of HIV therapy.

  Current opinion in HIV and AIDS 20070701

• Treatment strategies for HIV lipodystrophy.

  Current opinion in HIV and AIDS 20070701

• High throughput LC-MS/MS method for simultaneous quantification of lamivudine, stavudine and nevirapine in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070615

• Development of written information for antiretroviral therapy: comprehension in a Tanzanian population.

  Pharmacy world & science : PWS 20070601

• Effects of a nucleoside reverse transcriptase inhibitor, stavudine, on glucose disposal and mitochondrial function in muscle of healthy adults.

  American journal of physiology. Endocrinology and metabolism 20070601

• Therapeutic issues in HIV/HCV-coinfected patients.

  Journal of viral hepatitis 20070601

• Long-term complications of antiretroviral therapy: lipoatrophy.

  International journal of clinical practice 20070601

• HIV prevention, care, and treatment in two prisons in Thailand.

  PLoS medicine 20070601

• Expansion of HIV-1 screening and anti-retroviral treatment programs in a resource-poor setting: results from a faith-based organization in Jos, Plateau State, Nigeria.

  African health sciences 20070601

• FDA notifications. FDA grants approval for generic didanosine for oral solution.

  AIDS alert 20070601

• Alterations in circulating osteoimmune factors may be responsible for high bone resorption rate in HIV-infected children and adolescents.

  AIDS (London, England) 20070531

• Stability study of stavudine-loaded O-palmitoyl-anchored carbohydrate-coated liposomes.

  AAPS PharmSciTech 20070518

• Novel mutation of human DNA polymerase gamma associated with mitochondrial toxicity induced by anti-HIV treatment.

  The Journal of infectious diseases 20070515

• Determination of 19 antiretroviral agents in pharmaceuticals or suspected products with two methods using high-performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501

• [d4U]-butyne-[HI-236] as a non-cleavable, bifunctional NRTI/NNRTI HIV-1 reverse-transcriptase inhibitor.

  Bioorganic & medicinal chemistry letters 20070501

• Development and evaluation of an oligonucleotide ligation assay for detection of drug resistance-associated mutations in the human immunodeficiency virus type 2 pol gene.

  Journal of clinical microbiology 20070501

• Effect of efavirenz on the pharmacokinetics of ketoconazole in HIV-infected patients.

  European journal of clinical pharmacology 20070501

• Comparison of the phosphorylation of 4'-ethynyl 2',3'-dihydro-3'-deoxythymidine with that of other anti-human immunodeficiency virus thymidine analogs.

  Antimicrobial agents and chemotherapy 20070501

• Association between hepatitis C virus coinfection and regional adipose tissue volume in HIV-infected men and women.

  Journal of acquired immune deficiency syndromes (1999) 20070501

• Association of serum lipid levels with HIV serostatus, specific antiretroviral agents, and treatment regimens.

  Journal of acquired immune deficiency syndromes (1999) 20070501

• Tenofovir disoproxil fumarate for prevention of HIV infection in women: a phase 2, double-blind, randomized, placebo-controlled trial.

  PLoS clinical trials 20070501

• HIV treatment in a conflict setting: outcomes and experiences from Bukavu, Democratic Republic of the Congo.

  PLoS medicine 20070501

• Antiretroviral therapy in children: Indian experience.

  Indian pediatrics 20070501

• FDA notifications. FDA grants tentative approval to two ART drugs under expedited review.

  AIDS alert 20070501

• Enzymatically activated cycloSal-d4T-monophosphates: The third generation of cycloSal-pronucleotides.

  Journal of medicinal chemistry 20070405

• Antiretroviral-associated toxicity among HIV-1-seropositive pregnant women in Mozambique receiving nevirapine-based regimens.

  Journal of acquired immune deficiency syndromes (1999) 20070401

• Clinical toxicity of highly active antiretroviral therapy in a home-based AIDS care program in rural Uganda.

  Journal of acquired immune deficiency syndromes (1999) 20070401

• Synthesis and anti-HIV-1 activities of novel podophyllotoxin derivatives.

  Bioorganic & medicinal chemistry letters 20070401

• Systematic review of clinical trials evaluating low doses of stavudine as part of antiretroviral treatment.

  Expert opinion on pharmacotherapy 20070401

• Surveillance of genotypic resistance mutations in chronic HIV-1 treated individuals after completion of the National Access to Antiretroviral Program in Thailand.

  Infection 20070401

• ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia.

  PLoS pathogens 20070401

• Lack of effect of gastric acid-reducing agents on the pharmacokinetics of lopinavir/ritonavir in HIV-infected patients.

  AIDS patient care and STDs 20070401

• Clinical and electrophysiologic evaluation of peripheral neuropathy in a group of HIV-infected patients in Thailand.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20070401

• Dyslipidaemia associated with the highly active antiretroviral therapy in AIDS patient: reversion after switching (stavudine to tenofovir and lopinavir/ritonavir to atazanavir/ritonavir).

  The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20070401

• Nevirapine clearance from plasma in African adults stopping therapy: a pharmacokinetic substudy.

  AIDS (London, England) 20070330

• Long-term safety, effectiveness and quality of a generic fixed-dose combination of nevirapine, stavudine and lamivudine.

  AIDS (London, England) 20070330

• Bis-cycloSal-d4T-monophosphates: drugs that deliver two molecules of bioactive nucleotides.

  Journal of medicinal chemistry 20070322

• Highly selective action of triphosphate metabolite of 4'-ethynyl D4T: a novel anti-HIV compound against HIV-1 RT.

  Antiviral research 20070301

• Triple antiretroviral prophylaxis administered during pregnancy and after delivery significantly reduces breast milk viral load: a study within the Drug Resource Enhancement Against AIDS and Malnutrition Program.

  Journal of acquired immune deficiency syndromes (1999) 20070301

• Improved method to quantify intracellular zidovudine mono- and triphosphate in peripheral blood mononuclear cells by liquid chromatography-tandem mass spectrometry.

  Journal of mass spectrometry : JMS 20070301

• Evidence of ongoing immune reconstitution in subjects with sustained viral suppression following 6 years of lopinavir-ritonavir treatment.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070301

• Dyslipidemia in an Asian population after treatment for two years with protease inhibitor-containing regimens.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20070301

• Usage of stavudine (D4T) - a retrospective analysis in a South London hospital.

  International journal of STD & AIDS 20070301

• Factors in AIDS dementia complex trial design: results and lessons from the abacavir trial.

  PLoS clinical trials 20070301

• Mechanisms of resistance associated with excision of incorporated nucleotide analogue inhibitors of HIV-1 reverse transcriptase.

  Current opinion in HIV and AIDS 20070301

• [Antiretrovirals].

  Nihon rinsho. Japanese journal of clinical medicine 20070227

• Metabolic and anthropometric changes one year after switching from didanosine/stavudine to tenofovir in HIV-infected patients.

  European journal of medical research 20070226

• Initiation of antiretroviral therapy leads to a rapid decline in cervical and vaginal HIV-1 shedding.

  AIDS (London, England) 20070219

• Less lipoatrophy and better lipid profile with abacavir as compared to stavudine: 96-week results of a randomized study.

  Journal of acquired immune deficiency syndromes (1999) 20070201

• Modulation of human BCRP (ABCG2) activity by anti-HIV drugs.

  The Journal of antimicrobial chemotherapy 20070201

• Options for a second-line antiretroviral regimen for HIV type 1-infected patients whose initial regimen of a fixed-dose combination of stavudine, lamivudine, and nevirapine fails.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070201

• Drug resistance after failure of initial antiretroviral therapy in resource-limited countries.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070201

• Malawi's contribution to '3 by 5': achievements and challenges.

  Bulletin of the World Health Organization 20070201

• Preparation and in vitro evaluation of ethyl cellulose microspheres containing stavudine by the double emulsion method.

  Die Pharmazie 20070201

• Update in HIV care.

  Journal of general internal medicine 20070201

• [Severe thrombocytopenia and human immunodeficiency virus infection. Report of two cases and review].

  Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia 20070201

• Efficacy of a generic fixed-dose combination of stavudine, lamivudine and nevirapine (GPO-VIR) in Thai HIV-infected patients.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20070201

• Plasma nevirapine levels and 24-week efficacy of a fixed-dose combination of stavudine, lamivudine and nevirapine (GPO-VIR) among Thai HIV-infected patients.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20070201

• The value of highly active antiretroviral therapy in the prevention of mother-to-child transmission of HIV.

  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20070201

• Effect of system variables involved in packed column supercritical fluid chromatography of stavudine taken as model analyte using response surface methodology along with study of thermodynamic parameters.

  Journal of pharmaceutical and biomedical analysis 20070117

• Weight and body shape changes in a treatment-naive population after 6 months of nevirapine-based generic highly active antiretroviral therapy in South India.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070115

• Pharmacokinetic comparison of generic and trade formulations of lamivudine, stavudine and nevirapine in HIV-infected Malawian adults.

  AIDS (London, England) 20070102

• Transplacentally exposed human and monkey newborn infants show similar evidence of nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity.

  Environmental and molecular mutagenesis 20070101

• Unrecognized near-fatal hyperlactatemia in an HIV-infected infant exposed to nucleoside reverse transcriptase inhibitors.

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20070101

• Prevalence of lipodystrophy in HIV-infected children: a cross-sectional study.

  European journal of pediatrics 20070101

• Pharmacokinetics of two generic fixed-dose combinations for HIV-infected children (Pedimune Baby & Pedimune Junior) are similar to the branded products in healthy adults.

  The Journal of antimicrobial chemotherapy 20070101

• Relation of stavudine discontinuation to anthropometric changes among HIV-infected women.

  Journal of acquired immune deficiency syndromes (1999) 20070101

• A novel substrate-based HIV-1 protease inhibitor drug resistance mechanism.

  PLoS medicine 20070101

• Changes in the peripheral blood mtDNA levels in naive patients treated by different nucleoside reverse transcriptase inhibitor combinations and their association with subsequent lipodystrophy.

  AIDS research and human retroviruses 20070101

• Lack of indinavir-associated nephrological complications in HIV-infected adults (predominantly women) with high indinavir plasma concentration in Abidjan, Côte d'Ivoire.

  AIDS research and human retroviruses 20070101

• Computational models of antiviral toxicity.

  Current opinion in drug discovery & development 20070101

• Closing the access gap for health innovations: an open licensing proposal for universities.

  Globalization and health 20070101

• Baseline resistance to nucleoside reverse transcriptase inhibitors fails to predict virologic response to combination therapy in children (PACTG 338).

  AIDS research and therapy 20070101

• Experience with the use of a first-line regimen of stavudine, lamivudine and nevirapine in patients in the TREAT Asia HIV Observational Database.

  HIV medicine 20070101

• Cervical lipomatosis in HIV-infected patients: a case-control study.

  HIV medicine 20070101

• No association between HIV disease and its treatment and thyroid function.

  HIV medicine 20070101

• Mitochondrial DNA assessment in adipocytes and peripheral blood mononuclear cells of HIV-infected patients with lipodystrophy according to a validated case definition.

  HIV medicine 20070101

• Public health the leading force of the Indonesian response to the HIV/AIDS crisis among people who inject drugs.

  Harm reduction journal 20070101

• Retroviral rebound syndrome after treatment discontinuation in a 15 year old girl with HIV attracted through mother-to-child transmission: case report.

  AIDS research and therapy 20070101

• Methodological standards in non-inferiority AIDS trials: moving from adherence to compliance: response.

  BMC medical research methodology 20070101

• Plasma nevirapine levels, adverse events and efficacy of antiretroviral therapy among HIV-infected patients concurrently receiving nevirapine-based antiretroviral therapy and fluconazole.

  BMC infectious diseases 20070101

• Safety and efficacy of a generic fixed-dose combination of stavudine, lamivudine and nevirapine antiretroviral therapy between HIV-infected patients with baseline CD4 <50 versus CD4 > or = 50 cells/mm3.

  AIDS research and therapy 20070101

• Relative mutagenic potencies of several nucleoside analogs, alone or in drug pairs, at the HPRT and TK loci of human TK6 lymphoblastoid cells.

  Environmental and molecular mutagenesis 20070101

• Preliminary outcomes of a paediatric highly active antiretroviral therapy cohort from KwaZulu-Natal, South Africa.

  BMC pediatrics 20070101

• HIV/AIDS drugs for Sub-Saharan Africa: how do brand and generic supply compare?

  PloS one 20070101

• Anti-retroviral activity of GMP-grade stampidine against genotypically and phenotypically nucleoside reverse transcriptase inhibitor resistant recombinant human immunodeficiency virus. An in vitro study.

  Arzneimittel-Forschung 20070101

• Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection.

  Retrovirology 20070101

• Immunologic, virologic, and neuropsychologic responses in human immunodeficiency virus-infected children receiving their first highly active antiretroviral therapy regimen.

  Viral immunology 20070101

• Evaluation of human immunodeficiency virus type 1-infected Chinese patients treated with highly active antiretroviral therapy for two years.

  Viral immunology 20070101

• Resistance costs and future drug options of antiretroviral therapies: analysis of the role of NRTIs, NNRTIs, and PIs in a large clinical cohort.

  HIV clinical trials 20070101

• How labour intensive is a doctor-based delivery model for antiretroviral treatment (ART)? Evidence from an observational study in Siem Reap, Cambodia.

  Human resources for health 20070101

• Interpreting cerebrospinal fluid pleocytosis in HIV in the era of potent antiretroviral therapy.

  BMC infectious diseases 20070101

• Dideoxynucleoside HIV reverse transcriptase inhibitors and drug-related hepatotoxicity: a case report.

  Journal of medical case reports 20070101

• Low CD4 count plus coma predicts cryptococcal meningitis in Tanzania.

  BMC infectious diseases 20070101

• Relationship of mitochondrial DNA depletion and respiratory chain activity in preadipocytes treated with nucleoside reverse transcriptase inhibitors.

  Antiviral therapy 20070101

• Nevirapine concentrations in HIV-infected children treated with divided fixed-dose combination antiretroviral tablets in Malawi and Zambia.

  Antiviral therapy 20070101

• A virological benefit from an induction/maintenance strategy: the Forte trial.

  Antiviral therapy 20070101

• Plasma levels of soluble urokinase-type plasminogen activator receptor (suPAR) and early mortality risk among patients enrolling for antiretroviral treatment in South Africa.

  BMC infectious diseases 20070101

• Infections and immunosuppression as specific problems in a HIV + patient transplanted for end-stage alcoholic cirrhosis.

  Acta chirurgica Belgica 20070101

• AIDS in the Third World: how to stop the HIV infection?

  Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie 20070101

• Anti-HIV drugs.

  Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie 20070101

• Injection drug use and patterns of highly active antiretroviral therapy use: an analysis of ALIVE, WIHS, and MACS cohorts.

  AIDS research and therapy 20070101

• Healthcare utilization of patients accessing an African national treatment program.

  BMC health services research 20070101

• Normalization of fat accrual in lipoatrophic, HIV-infected children switched from stavudine to tenofovir and from protease inhibitor to efavirenz.

  Antiviral therapy 20070101

• High doses of stavudine induce fat wasting and mild liver damage without impairing mitochondrial respiration in mice.

  Antiviral therapy 20070101

• The impact of reducing stavudine dose versus switching to tenofovir on plasma lipids, body composition and mitochondrial function in HIV-infected patients.

  Antiviral therapy 20070101

• HIV-associated adipose redistribution syndrome (HARS): etiology and pathophysiological mechanisms.

  AIDS research and therapy 20070101

• Polymorphisms and drug resistance analysis of HIV-1 CRF01_AE strains circulating in Fujian Province, China.

  Archives of virology 20070101

• Protease inhibitor associated mutations compromise the efficacy of therapy in human immunodeficiency virus-1 (HIV-1) infected pediatric patients: a cross-sectional study.

  AIDS research and therapy 20070101

• The safety and efficacy of tenofovir DF in combination with lamivudine and efavirenz through 6 years in antiretroviral-naïve HIV-1-infected patients.

  HIV clinical trials 20070101

• Phenotype and envelope gene diversity of nef-deleted HIV-1 isolated from long-term survivors infected from a single source.

  Virology journal 20070101

• A national survey of teachers on antiretroviral therapy in Malawi: access, retention in therapy and survival.

  PloS one 20070101

• Nucleoside and nucleotide reverse transcriptase inhibitors in children.

  Clinical drug investigation 20070101

• Electrospray tandem mass spectroscopic characterisation of 18 antiretroviral drugs and simultaneous quantification of 12 antiretrovirals in plasma.

  Rapid communications in mass spectrometry : RCM 20070101

• Evaluation of the prevalence and economic burden of adverse drug reactions presenting to the medical emergency department of a tertiary referral centre: a prospective study.

  BMC clinical pharmacology 20070101

• Some HIV antiretrovirals increase oxidative stress and alter chemokine, cytokine or adiponectin production in human adipocytes and macrophages.

  Antiviral therapy 20070101

• Nevirapine-based antiretroviral therapy started early in the course of tuberculosis treatment in adult Malawians.

  Antiviral therapy 20070101

• Three-year immune reconstitution in PI-sparing and PI-containing antiretroviral regimens in advanced HIV-1 disease.

  Antiviral therapy 20070101

• Update on the treatment of chronic hepatitis C in HIV-infected patients.

  AIDS reviews 20070101

• Substitutions due to antiretroviral toxicity or contraindication in the first 3 years of antiretroviral therapy in a large South African cohort.

  Antiviral therapy 20070101

• Changes in facial fat in HIV-related lipoatrophy, wasting, and weight gain measured by magnetic resonance imaging.

  HIV clinical trials 20070101

• Impact of drug classes and treatment availability on the rate of antiretroviral treatment change in the TREAT Asia HIV Observational Database (TAHOD).

  AIDS research and therapy 20070101

• Assessment of quality of life in HAART-treated HIV-positive subjects with body fat redistribution in Rwanda.

  AIDS research and therapy 20070101

• Pulmonary cystic disease in HIV positive individuals in the Democratic Republic of Congo: three case reports.

  Journal of medical case reports 20070101

• Immune restoration syndrome with disseminated Penicillium marneffei and cytomegalovirus co-infections in an AIDS patient.

  AIDS research and therapy 20070101

• Mitochondrial toxicity of indinavir, stavudine and zidovudine involves multiple cellular targets in white and brown adipocytes.

  Antiviral therapy 20070101

• Intracellular nucleoside triphosphate concentrations in HIV-infected patients on dual nucleoside reverse transcriptase inhibitor therapy.

  Antiviral therapy 20070101

• Stavudine but not didanosine as part of HAART contributes to peripheral lipoatrophy: a substudy from the Antiretroviral Regimen Evaluation Study (ARES).

  HIV clinical trials 20070101

• Poor follow-up rates at a self-pay northern Indian tertiary AIDS clinic.

  International journal for equity in health 20070101

• Decreasing CD4+ T-cell count during suppressed or low-level viraemia in patients with HIV infection.

  Antiviral therapy 20070101

• Mitochondrial toxicity of tenofovir, emtricitabine and abacavir alone and in combination with additional nucleoside reverse transcriptase inhibitors.

  Antiviral therapy 20070101

• Rapid CD4 decline after interruption of non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy in a resource-limited setting.

  AIDS research and therapy 20070101

• Cost-effectiveness of tipranavir versus comparator protease inhibitor regimens in HIV infected patients previously exposed to antiretroviral therapy in the Netherlands.

  Cost effectiveness and resource allocation : C/E 20070101

• The safety and efficacy of switching stavudine to tenofovir df in combination with lamivudine and efavirenz in hiv-1-infected patients: three-year follow-up after switching therapy.

  HIV clinical trials 20070101

• [Isosteric triphosphonate analogues of dNTP: synthesis and substrate properties toward various DNA polymerases].

  Bioorganicheskaia khimiia 20070101

• Validation of high-performance liquid chromatography methods for determination of zidovudine, stavudine, lamivudine and indinavir in human plasma.

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20070101

• New developments of the 'lock-in' modified cycloSal-d4TMPs.

  Nucleosides, nucleotides & nucleic acids 20070101

• Synthetic use of epoxy-sugar nucleosides.

  Nucleosides, nucleotides & nucleic acids 20070101

• An alternative synthetic method for 4'-C-ethynylstavudine by means of nucleophilic substitution of 4'-benzoyloxythymine nucleoside.

  Nucleosides, nucleotides & nucleic acids 20070101

• 5-diacetoxymethyl-cycloSal-d4TMP - A prototype of enzymatically activated cycloSal-pronucleotides.

  Nucleosides, nucleotides & nucleic acids 20070101

• Lipodystrophy and metabolic changes in HIV-infected children on non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy.

  Antiviral therapy 20070101

• A 6-month interruption of antiretroviral therapy improves adipose tissue function in HIV-infected patients: the ANRS EP29 Lipostop Study.

  Antiviral therapy 20070101

• Poor efficacy and tolerability of stavudine, didanosine, and efavirenz-based regimen in treatment-naive patients in Senegal.

  MedGenMed : Medscape general medicine 20070101

• The balance between NRTI discrimination and excision drives the susceptibility of HIV-1 RT mutants K65R, M184V and K65r+M184V.

  Antiviral chemistry & chemotherapy 20070101

• A cluster-randomised trial to compare home-based with health facility-based antiretroviral treatment in Uganda: study design and baseline findings.

  The open AIDS journal 20070101

• [The clinical and biological tolerance of nevirapine among patients with AIDS under treatment at the Hospital of the Point G].

  Le Mali medical 20070101

• Clinical implications of mutations at reverse transcriptase codon 135 on response to NNRTI-based therapy.

  The open virology journal 20070101

• [Cutaneous side effects of antiretroviral drugs].

  Le Mali medical 20070101

• [Factors associated with antiretroviaral treatment observance at Point 'G' hospital].

  Le Mali medical 20070101

• Poor Efficacy and Tolerability of Stavudine, Didanosine, and Efavirenz-based Regimen in Treatment-Naive Patients in Senegal.

  Journal of the International AIDS Society 20070101

• Insights on resistance to reverse transcriptase: the different patterns of interaction of the nucleoside reverse transcriptase inhibitors in the deoxyribonucleotide triphosphate binding site relative to the normal substrate.

  Journal of medicinal chemistry 20061228

• Synthesis, in vitro antiviral evaluation, and stability studies of novel alpha-borano-nucleotide analogues of 9-[2-(phosphonomethoxy)ethyl]adenine and (R)-9-[2-(phosphonomethoxy)propyl]adenine.

  Journal of medicinal chemistry 20061228

• Synthesis and anti-human immunodeficiency virus activity of 4'-branched (+/-)-4'-thiostavudines.

  Journal of medicinal chemistry 20061228

• Severity of the toxicity associated with combinations that include didanosine plus stavudine in HIV-infected experienced patients.

  Journal of acquired immune deficiency syndromes (1999) 20061215

• Protective effect of acetyl-L-carnitine against oxidative stress induced by antiretroviral drugs.

  FEBS letters 20061211

• Induction of thymidine phosphorylase expression by AZT contributes to enhancement of 5'-DFUR cytotoxicity.

  Cancer letters 20061208

• Nucleoside reverse transcriptase inhibitors prevent HIV protease inhibitor-induced atherosclerosis by ubiquitination and degradation of protein kinase C.

  American journal of physiology. Cell physiology 20061201

• In vitro human immunodeficiency virus type 1 resistance selections with combinations of tenofovir and emtricitabine or abacavir and lamivudine.

  Antimicrobial agents and chemotherapy 20061201

• Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection.

  PLoS medicine 20061201

• Five-year data out on Viread.

  AIDS patient care and STDs 20061201

• The effects of highly active antiretroviral therapy (HAART) of stavudine, lamivudine and nevirapine on the CD4 lymphocyte count of HIV-infected Africans: the Nigerian experience.

  Nigerian journal of clinical practice 20061201

• Nanomedicines in the treatment of patients with hepatitis C co-infected with HIV--focus on pegylated interferon-alpha.

  International journal of nanomedicine 20061201

• Enantioseparation of cis and trans nucleosides, aromatic analogues of stavudine, by capillary electrophoresis and high-performance liquid chromatography.

  Journal of chromatography. A 20061103

• Long-term results of initial therapy with abacavir and Lamivudine combined with Efavirenz, Amprenavir/Ritonavir, or Stavudine.

  Journal of acquired immune deficiency syndromes (1999) 20061101

• Criteria for drugs used in pre-exposure prophylaxis trials against HIV infection.

  PLoS medicine 20061101

• A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy.

  AIDS (London, England) 20061024

• Long-term assessment of nevirapine-containing highly active antiretroviral therapy in antiretroviral-naive HIV-infected patients: 3-year follow-up of the VIRGO study.

  HIV medicine 20061001

• Resistance development over 144 weeks in treatment-naive patients receiving tenofovir disoproxil fumarate or stavudine with lamivudine and efavirenz in Study 903.

  HIV medicine 20061001

• Clinical and economic outcomes of nonadherence to highly active antiretroviral therapy in patients with human immunodeficiency virus.

  Medical care 20061001

• Effect of alkyl groups on the cellular hydrolysis of stavudine phosphoramidates.

  Bioorganic & medicinal chemistry 20060915

• Application of the cycloSal-prodrug approach for improving the biological potential of phosphorylated biomolecules.

  Antiviral research 20060901

• Monitoring the toxicity of antiretroviral therapy in resource limited settings: a prospective clinical trial cohort in Thailand.

  The Journal of antimicrobial chemotherapy 20060901

• Rates of disease progression according to initial highly active antiretroviral therapy regimen: a collaborative analysis of 12 prospective cohort studies.

  The Journal of infectious diseases 20060901

• Changes in body composition and mitochondrial nucleic acid content in patients switched from failed nucleoside analogue therapy to ritonavir-boosted indinavir and efavirenz.

  The Journal of infectious diseases 20060901

• Plasma lipid concentrations after 1.5 years of exposure to nevirapine or efavirenz together with stavudine and lamivudine.

  HIV medicine 20060901

• The value of serum albumin in pretreatment assessment and monitoring of therapy in HIV/AIDS patients.

  HIV medicine 20060901

• Lessons learned from a paying antiretroviral therapy service in the public health sector at Kamuzu Central Hospital, Malawi: 1-year experience.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20060901

• Discontinuation of highly active antiretroviral therapy leads to cryptococcal meningitis/choroiditis in an AIDS patient.

  Optometry (St. Louis, Mo.) 20060901

• Virological and immunological responses of efavirenz-based HAART regimen initiated in HIV-infected patients at CD4 < 100 versus CD4 > or = 100 cells/mm3.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20060901

• Efficacy and safety of generic fixed-dose combination of stavudine, lamivudine and nevirapine (GPO-vir) in advanced HIV infection.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20060901

• Microarray analysis during adipogenesis identifies new genes altered by antiretroviral drugs.

  AIDS (London, England) 20060822

• Fat distribution in women with HIV infection.

  Journal of acquired immune deficiency syndromes (1999) 20060815

• Micronutrient supplementation increases CD4 count in HIV-infected individuals on highly active antiretroviral therapy: a prospective, double-blinded, placebo-controlled trial.

  Journal of acquired immune deficiency syndromes (1999) 20060815

• Adverse effects of antiretroviral therapy in HIV-1 infected children.

  Journal of tropical pediatrics 20060801

• Synthesis and metabolism of naphthyl substituted phosphoramidate derivatives of stavudine.

  Bioorganic & medicinal chemistry 20060801

• Hepatic steatosis is associated with fibrosis, nucleoside analogue use, and hepatitis C virus genotype 3 infection in HIV-seropositive patients.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060801

• [Central nervous system HIV-associated polyarteritis nodosa: long-term outcome].

  La Revue de medecine interne 20060801

• Novel nonnucleoside inhibitors that select nucleoside inhibitor resistance mutations in human immunodeficiency virus type 1 reverse transcriptase.

  Antimicrobial agents and chemotherapy 20060801

• How do intellectual property law and international trade agreements affect access to antiretroviral therapy?

  PLoS medicine 20060801

• A high incidence of nucleoside reverse transcriptase inhibitor (NRTI)-induced lactic acidosis in HIV-infected patients in a South African context.

  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20060801

• Characteristics of HIV infected patients cared for at 'academic model for the prevention and treatment of HIV/AIDS' clinics in western Kenya.

  East African medical journal 20060801

• Structured treatment interruptions following immediate initiation of HAART in eight patients with acute HIV-1 seroconversion.

  European journal of medical research 20060731

• National adult antiretroviral therapy guidelines in resource-limited countries: concordance with 2003 WHO guidelines?

  AIDS (London, England) 20060713

• Hemochromatosis (HFE) gene mutations and peripheral neuropathy during antiretroviral therapy.

  AIDS (London, England) 20060713

• High serum urate in HIV-infected persons: the choice of the antiretroviral drug matters.

  AIDS (London, England) 20060713

• Age and sex modulate metabolic and cardiovascular risk markers of patients after 1 year of highly active antiretroviral therapy (HAART).

  Atherosclerosis 20060701

• Distal sensory polyneuropathy in HIV-positive patients in the HAART era: an entity underestimated by clinical examination.

  International journal of STD & AIDS 20060701

• A randomised trial comparing genotypic and virtual phenotypic interpretation of HIV drug resistance: the CREST study.

  PLoS clinical trials 20060701

• Hepatic steatosis and ddI, d4T use.

  IAPAC monthly 20060701

• Sustained improvement of dyslipidaemia in HAART-treated patients replacing stavudine with tenofovir.

  AIDS (London, England) 20060626

• Nucleophilic substitution at the 4'-position of nucleosides: new access to a promising anti-HIV agent 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine.

  The Journal of organic chemistry 20060609

• Simultaneous determination of lamivudine and stavudine in antiretroviral fixed dose combinations by first derivative spectrophotometry and high performance liquid chromatography.

  Journal of pharmaceutical and biomedical analysis 20060607

• Real-time nucleic acid sequence-based amplification assay to quantify changes in mitochondrial DNA concentrations in cell cultures and blood cells from HIV-infected patients receiving antiviral therapy.

  Clinical chemistry 20060601

• Improving access to medicines in poor countries: the role of universities.

  PLoS medicine 20060601

• Antiviral activity of nucleoside analogues during short-course monotherapy or dual therapy: its role in preventing HIV infection in infants.

  Journal of acquired immune deficiency syndromes (1999) 20060601

• The role of hydroxyurea in enhancing the virologic control achieved through structured treatment interruption in primary HIV infection: final results from a randomized clinical trial (Pulse).

  Journal of acquired immune deficiency syndromes (1999) 20060601

• Severe liver disease associated with prolonged exposure to antiretroviral drugs.

  Journal of acquired immune deficiency syndromes (1999) 20060601

• Antiretroviral drug resistance and routine therapy, Cameroon.

  Emerging infectious diseases 20060601

• Prenatal developmental toxicity evaluation of 2',3'-dideoxyinosine (ddI) and 2',3'-didehydro-3'-deoxythymidine (d4T) co-administered to Swiss Albino (CD-1) mice.

  Birth defects research. Part B, Developmental and reproductive toxicology 20060601

• Analysis and validation of the phosphorylated metabolites of two anti-human immunodeficiency virus nucleotides (stavudine and didanosine) by pressure-assisted CE-ESI-MS/MS in cell extracts: sensitivity enhancement by the use of perfluorinated acids and alcohols as coaxial sheath-liquid make-up constituents.

  Electrophoresis 20060601

• Nevirapine/lamivudine/stavudine as a combined-formulation tablet: bioequivalence study compared with each component administered concurrently under fasting condition.

  International journal of clinical pharmacology and therapeutics 20060601

• [Hypothyroidisms induced by drugs].

  Nihon rinsho. Japanese journal of clinical medicine 20060528

• Generic fixed-dose combination antiretroviral treatment in resource-poor settings: multicentric observational cohort.

  AIDS (London, England) 20060512

• Natural polymorphism in protease and reverse transcriptase genes and in vitro antiretroviral drug susceptibilities of non-B HIV-1 strains from treatment-naive patients.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20060501

• Improvement of dyslipidemia during different HAART regimens: tenofovir- versus stavudine-containing antiretroviral combinations.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Adverse effects of antiretroviral drugs on HIV-1-infected and -uninfected human monocyte-derived macrophages.

  Journal of acquired immune deficiency syndromes (1999) 20060501

• Stavudine-loaded mannosylated liposomes: in-vitro anti-HIV-I activity, tissue distribution and pharmacokinetics.

  The Journal of pharmacy and pharmacology 20060501

• Detection of lipoatrophy in human immunodeficiency virus-1-infected children treated with highly active antiretroviral therapy.

  The Pediatric infectious disease journal 20060501

• Stavudine, lamivudine and nevirapine combination therapy for treatment of HIV infection and AIDS in adults.

  The Cochrane database of systematic reviews 20060419

• Effect of co-trimoxazole prophylaxis, antiretroviral therapy, and insecticide-treated bednets on the frequency of malaria in HIV-1-infected adults in Uganda: a prospective cohort study.

  Lancet (London, England) 20060415

• Mixed patterns of changes in central and peripheral fat following initiation of antiretroviral therapy in a randomized trial.

  Journal of acquired immune deficiency syndromes (1999) 20060415

• Thermodynamic modeling of activity coefficient and prediction of solubility: Part 2. Semipredictive or semiempirical models.

  Journal of pharmaceutical sciences 20060401

• Thyroid function in human immunodeficiency virus patients treated with highly active antiretroviral therapy (HAART): a longitudinal study.

  Clinical endocrinology 20060401

• Successful miltefosine treatment of post-kala-azar dermal leishmaniasis occurring during antiretroviral therapy.

  Annals of tropical medicine and parasitology 20060401

• The 118I reverse transcriptase mutation is the only independent genotypic predictor of virologic failure to a stavudine-containing salvage therapy in HIV-1-infected patients.

  Journal of acquired immune deficiency syndromes (1999) 20060401

• Antiretroviral use and other risks for HIV-associated neuropathies in an international cohort.

  Neurology 20060328

• Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis.

  AIDS (London, England) 20060321

• Associations among race/ethnicity, ApoC-III genotypes, and lipids in HIV-1-infected individuals on antiretroviral therapy.

  PLoS medicine 20060301

• A prospective, 96-week study of the impact of Trizivir, Combivir/nelfinavir, and lamivudine/stavudine/nelfinavir on lipids, metabolic parameters and efficacy in antiretroviral-naive patients: effect of sex and ethnicity.

  HIV medicine 20060301

• Long-term experience with combination antiretroviral therapy that contains nelfinavir for up to 7 years in a pediatric cohort.

  Pediatrics 20060301

• Pharmacokinetic parameters of nevirapine and efavirenz in relation to antiretroviral efficacy.

  AIDS research and human retroviruses 20060301

• How to Take HIV antiretroviral medications on time without a watch in rural Uganda.

  PLoS medicine 20060301

• Simultaneous determination of 16 anti-HIV drugs in human plasma by high-performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060202

• Synthesis and conformational analysis of new cyclobutane-fused nucleosides.

  Organic letters 20060202

• Optimization of diarylamines as non-nucleoside inhibitors of HIV-1 reverse transcriptase.

  Bioorganic & medicinal chemistry letters 20060201

• Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it.

  Mitochondrion 20060201

• In vitro antiretroviral activity and in vitro toxicity profile of SPD754, a new deoxycytidine nucleoside reverse transcriptase inhibitor for treatment of human immunodeficiency virus infection.

  Antimicrobial agents and chemotherapy 20060201

• Effects of discontinuing stavudine or protease inhibitor therapy on human immunodeficiency virus-related fat redistribution evaluated by dual-energy x-ray absorptiometry.

  Pharmacotherapy 20060201

• [Clinical trial comparing efficacy and safety of four highly active antiretroviral therapy (HAART) in antiretroviral-naive treatment with advanced HIV infection].

  Revista clinica espanola 20060201

• FDA notifications. FDA grants tentative approval to generic stavudine.

  AIDS alert 20060201

• Unmet challenges in HIV therapy and potential of stampidine.

  Arzneimittel-Forschung 20060201

• Stampidine as a novel nucleoside reverse transcriptase inhibit with potent anti-HIV activity.

  Arzneimittel-Forschung 20060201

• Large-scale synthesis and formulation of GMP-grade stampidine, a new anti-HIV agent.

  Arzneimittel-Forschung 20060201

• Synthesis, separation and anti-HIV activity of distereoisomers of N-[p-(4-bromophenyl) -2',3'-didehydro-3'-deoxy-5'-thymidylyl]-L-alanine methyl ester (stampidine).

  Arzneimittel-Forschung 20060201

• Developmental safety profile of the anti-HIV agent stampidine in rabbits.

  Arzneimittel-Forschung 20060201

• Site-specific enzymatic activation of the anti-HIV agent stampidine.

  Arzneimittel-Forschung 20060201

• In vivo pharmacokinetics and toxicity profile of the anti-HIV agent stampidine in dogs and feline immunodeficiency virus-infected cats.

  Arzneimittel-Forschung 20060201

• Potency of stampidine against multi-nucleoside reverse transcriptase inhibitor resistant human immunodeficiency viruses.

  Arzneimittel-Forschung 20060201

• Development and validation of RP-HPLC and ultraviolet spectrophotometric methods of analysis for the quantitative estimation of antiretroviral drugs in pharmaceutical dosage forms.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060118

• Suspected drug-induced liver fatalities reported to the WHO database.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20060101

• Impact of unreported HIV-1 reverse transcriptase mutations on phenotypic resistance to nucleoside and non-nucleoside inhibitors.

  Journal of medical virology 20060101

• Emtricitabine, a new antiretroviral agent with activity against HIV and hepatitis B virus.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060101

• Improved lipid profiles and maintenance of virologic control in heavily pretreated HIV-infected patients who switched from stavudine to tenofovir treatment.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060101

• Reasons for modification of generic highly active antiretroviral therapeutic regimens among patients in southern India.

  Journal of acquired immune deficiency syndromes (1999) 20060101

• Patients experiencing early virologic failure on a protease inhibitor- or nonnucleoside reverse transcriptase inhibitor-based initial regimen containing a thymidine analogue and Lamivudine can be successfully treated with a quadruple-nucleoside regimen.

  Journal of acquired immune deficiency syndromes (1999) 20060101

• Antiviral hepatitis and antiretroviral drug interactions.

  Journal of hepatology 20060101

• The distribution of the anti-HIV drug, tenofovir (PMPA), into the brain, CSF and choroid plexuses.

  Cerebrospinal fluid research 20060101

• [Mitochondrial cytopathies associated with HIV infection].

  Revue neurologique 20060101

• A prospective study of hearing changes after beginning zidovudine or didanosine in HIV-1 treatment-naïve people.

  BMC infectious diseases 20060101

• Adhesive capsulitis of the shoulder in human immunodeficiency virus-positive patients during highly active antiretroviral therapy.

  Journal of shoulder and elbow surgery 20060101

• Uridine abrogates the adverse effects of antiretroviral pyrimidine analogues on adipose cell functions.

  Antiviral therapy 20060101

• DR_SEQAN: a PC/Windows-based software to evaluate drug resistance using human immunodeficiency virus type 1 genotypes.

  BMC infectious diseases 20060101

• Effects of chronic stavudine exposure on liver, pancreas and kidneys of pregnant rats and their fetuses: morphological and biochemical aspects.

  European journal of obstetrics, gynecology, and reproductive biology 20060101

• Assessing the effect of HAART on change in quality of life among HIV-infected women.

  AIDS research and therapy 20060101

• CD4 cell count recovery among HIV-infected patients with very advanced immunodeficiency commencing antiretroviral treatment in sub-Saharan Africa.

  BMC infectious diseases 20060101

• Antiretroviral treatment of HIV infection: Swedish recommendations 2005.

  Scandinavian journal of infectious diseases 20060101

• Cerebrospinal fluid HIV-1 RNA, intrathecal immunoactivation, and drug concentrations after treatment with a combination of saquinavir, nelfinavir, and two nucleoside analogues: the M61022 study.

  BMC infectious diseases 20060101

• Antiretroviral therapy at a district hospital in Ethiopia prevents death and tuberculosis in a cohort of HIV patients.

  AIDS research and therapy 20060101

• Clinically stable treatment-experienced adults receiving tenofovir and didanosine.

  HIV clinical trials 20060101

• The K65R reverse transcriptase mutation in HIV-1 reverses the excision phenotype of zidovudine resistance mutations.

  Antiviral therapy 20060101

• Evaluation of the HIV lipodystrophy case definition in a placebo-controlled, 144-week study in antiretroviral-naive adults.

  Antiviral therapy 20060101

• Antiviral efficacy and genotypic resistance patterns of combination therapy with stavudine/tenofovir in highly active antiretroviral therapy experienced patients.

  Antiviral therapy 20060101

• Subclinical hypothyroidism in HIV-infected patients is not an autoimmune disease.

  Hormone research 20060101

• Insertions and deletions in HIV-1 reverse transcriptase: consequences for drug resistance and viral fitness.

  Current pharmaceutical design 20060101

• A placebo-controlled pilot study of intensification of antiretroviral therapy with mycophenolate mofetil.

  AIDS research and therapy 20060101

• Treating HIV during pregnancy: an update on safety issues.

  Drug safety 20060101

• Determination of didanosine in maternal plasma, amniotic fluid, fetal and placental tissues by high-performance liquid chromatography-tandem mass spectrometry.

  Biomedical chromatography : BMC 20060101

• 2'-deoxy-4'-C-ethynyl-2-fluoroadenosine, a nucleoside reverse transcriptase inhibitor, is highly potent against all human immunodeficiency viruses type 1 and has low toxicity.

  Chemical record (New York, N.Y.) 20060101

• Concentration of circulating oxidized LDL in HIV-infected patients treated with antiretroviral agents: relation to HIV-related lipodystrophy.

  HIV clinical trials 20060101

• Bioavailability study of two oral formulations of didanosine in healthy volunteers.

  Arzneimittel-Forschung 20060101

• Effects of highly active antiretroviral therapy with nelfinavir in vertically HIV-1 infected children: 3 years of follow-up. Long-term response to nelfinavir in children.

  BMC infectious diseases 20060101

• Influence of hepatitis C genotypes on lipid levels in HIV-positive patients during highly active antiretroviral therapy.

  Antiviral therapy 20060101

• Mild to moderate symptoms do not correlate with lactate levels in HIV-positive patients on nucleoside reverse transcriptase inhibitors.

  HIV clinical trials 20060101

• Affordable flow cytometry for enumeration of absolute CD4+ T-lymphocytes to identify subtype C HIV-1 infected adults requiring antiretroviral therapy (ART) and monitoring response to ART in a resource-limited setting.

  Journal of translational medicine 20060101

• Oral manifestations of HIV infection in children and adults receiving highly active anti-retroviral therapy [HAART] in Dar es Salaam, Tanzania.

  BMC oral health 20060101

• Predictors of early death in a cohort of Ethiopian patients treated with HAART.

  BMC infectious diseases 20060101

• Is oxygen a key factor in the lipodystrophy phenotype?

  Lipids in health and disease 20060101

• Lipid profile during pregnancy in HIV-infected women.

  HIV clinical trials 20060101

• Rapid propagation of low-fitness drug-resistant mutants of human immunodeficiency virus type 1 by a streptococcal metabolite sparsomycin.

  Antiviral chemistry & chemotherapy 20060101

• Tenofovir plus didanosine as Nrti backbone in HIV-infected subjects.

  Current medicinal chemistry 20060101

• Morphologic and immunophenotypic evidence of in-situ Kaposi's sarcoma.

  BMC clinical pathology 20060101

• Therapeutic challenges in hepatitis C-infected injection drug using patients.

  Harm reduction journal 20060101

• The cost-effectiveness of antiretroviral treatment in Khayelitsha, South Africa--a primary data analysis.

  Cost effectiveness and resource allocation : C/E 20060101

• Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal.

  PloS one 20060101

• Clinical outcome of HIV-infected patients with sustained virologic response to antiretroviral therapy: long-term follow-up of a multicenter cohort.

  PloS one 20060101

• Use of taste-masking product, FLAVORx, to assist Thai children to ingest generic antiretrovirals.

  AIDS research and therapy 20060101

• Acceptance of anti-retroviral therapy among patients infected with HIV and tuberculosis in rural Malawi is low and associated with cost of transport.

  PloS one 20060101

• Switching strategies to improve lipid profile and morphologic changes.

  AIDS reviews 20060101

• Antiretroviral therapy based on protease inhibitors as a protective factor against liver fibrosis progression in patients with chronic hepatitis C.

  Antiviral therapy 20060101

• Antiretroviral therapy at conception in pregnant women with HIV in Italy: wide range of variability and frequent exposure to contraindicated drugs.

  Antiviral therapy 20060101

• HIV-1 transmission cluster with M41L 'singleton' mutation and decreased transmission of resistance in newly diagnosed Swedish homosexual men.

  Antiviral therapy 20060101

• Disease Management - Constructing Optimal NRTI-Based Combinations: Past, Present, and Future.

  Journal of the International AIDS Society 20060101

• Synthesis and in vitro anti-mycobacterial activity of 5-substituted pyrimidine nucleosides.

  Bioorganic & medicinal chemistry 20051215

• Assessment of adipokine expression and mitochondrial toxicity in HIV patients with lipoatrophy on stavudine- and zidovudine-containing regimens.

  Journal of acquired immune deficiency syndromes (1999) 20051215

• Efficacy of cerebrospinal fluid (CSF)-penetrating antiretroviral drugs against HIV in the neurological compartment: different patterns of phenotypic resistance in CSF and plasma.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051215

• Spontaneous hepatic decompensation in patients coinfected with HIV and hepatitis C virus during interferon-ribavirin combination treatment.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051215

• A 12-month treatment with tenofovir does not impair bone mineral accrual in HIV-infected children.

  Journal of acquired immune deficiency syndromes (1999) 20051201

• Chronic hepatitis C in patients with HIV/AIDS: a new challenge in antiviral therapy.

  The Journal of antimicrobial chemotherapy 20051201

• Tumour necrosis factor alpha in fat redistribution syndromes associated with combination antiretroviral therapy in HIV-1-infected patients: potential role in subcutaneous adipocyte apoptosis.

  European journal of clinical investigation 20051201

• Stavudine.

  Acta crystallographica. Section C, Crystal structure communications 20051201

• Allosteric modulation of anti-HIV drug and ferric heme binding to human serum albumin.

  The FEBS journal 20051201

• Are all non-thymidine analogue backbones appropriate for treating antiretroviral-naïve patients?

  International journal of clinical practice 20051201

• T-cell response of advanced aids patients after highly active antiretroviral therapy.

  Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20051201

• Side effects and complications. Does switching therapy away from d4T help the face?

  TreatmentUpdate 20051201

• Mitochondrial DNA and RNA increase in peripheral blood mononuclear cells from HIV-1-infected patients randomized to receive stavudine-containing or stavudine-sparing combination therapy.

  The Journal of infectious diseases 20051115

• A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT.

  AIDS (London, England) 20051104

• Glucose metabolism, lipid, and body fat changes in antiretroviral-naive subjects randomized to nelfinavir or efavirenz plus dual nucleosides.

  AIDS (London, England) 20051104

• Initial response to highly active antiretroviral therapy in HIV-1C-infected adults in a public sector treatment program in Botswana.

  Journal of acquired immune deficiency syndromes (1999) 20051101

• Impact of antiretroviral choice on hypercholesterolaemia events: the role of the nucleoside reverse transcriptase inhibitor backbone.

  HIV medicine 20051101

• Antiretroviral treatment in the Northern Cape.

  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20051101

• Determination of antiretroviral agents in human serum by capillary electrophoresis.

  Journal of chromatography. A 20051014

• Fat distribution in men with HIV infection.

  Journal of acquired immune deficiency syndromes (1999) 20051001

• Oxadiazols: a new class of rationally designed anti-human immunodeficiency virus compounds targeting the nuclear localization signal of the viral matrix protein.

  Journal of virology 20051001

• Efficacy, tolerability and pharmacokinetics of two nelfinavir-based regimens in human immunodeficiency virus-infected children and adolescents: pediatric AIDS clinical trials group protocol 403.

  The Pediatric infectious disease journal 20051001

• Self-perception of body changes in persons living with HIV/AIDS: prevalence and associated factors.

  AIDS (London, England) 20051001

• Lactic acidosis in HIV infected children due to antiretroviral therapy.

  Indian pediatrics 20051001

• When do children convert from liquid antiretroviral to solid formulations?

  Pharmacy world & science : PWS 20051001

• Efavirenz levels and 24-week efficacy in HIV-infected patients with tuberculosis receiving highly active antiretroviral therapy and rifampicin.

  AIDS (London, England) 20050923

• Pharmacokinetics of nevirapine in HIV-infected children receiving an adult fixed-dose combination of stavudine, lamivudine and nevirapine.

  AIDS (London, England) 20050923

• Simultaneous quantification of stavudine, lamivudine and nevirapine by UV spectroscopy, reverse phase HPLC and HPTLC in tablets.

  Journal of pharmaceutical and biomedical analysis 20050915

• Effect of change in nucleoside structure on the activation and antiviral activity of phosphoramidate derivatives.

  Bioorganic & medicinal chemistry 20050915

• Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: an adult AIDS clinical trials group study.

  AIDS (London, England) 20050902

• Cumulative exposure to nucleoside analogue reverse transcriptase inhibitors is associated with insulin resistance markers in the Multicenter AIDS Cohort Study.

  AIDS (London, England) 20050902

• Genotypic and phenotypic resistance patterns at virological failure in a simplification trial with nevirapine, efavirenz or abacavir.

  AIDS (London, England) 20050902

• Hepatic steatosis with stavudine in HIV/hepatitis C virus co-infection.

  AIDS (London, England) 20050902

• Depleted skeletal muscle mitochondrial DNA, hyperlactatemia, and decreased oxidative capacity in HIV-infected patients on highly active antiretroviral therapy.

  Journal of medical virology 20050901

• Risk factors for and outcome of hyperlactatemia in HIV-infected persons: is there a need for routine lactate monitoring?

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050901

• Risk factors for symptomatic mitochondrial toxicity in HIV/hepatitis C virus-coinfected patients during interferon plus ribavirin-based therapy.

  Journal of acquired immune deficiency syndromes (1999) 20050901

• Management of HIV-1 infection with a combination of nevirapine, stavudine, and lamivudine: a preliminary report on the Nigerian antiretroviral program.

  Journal of acquired immune deficiency syndromes (1999) 20050901

• Epidural spinal lipomatosis with acute onset of paraplegia in an HIV-positive patient treated with corticosteroids and protease inhibitor: case report.

  Spine 20050901

• The ICH guidance in practice: stress degradation studies on stavudine and development of a validated specific stability-indicating HPTLC assay method.

  Journal of chromatographic science 20050901

• Long-term complete remission of laryngeal Kaposi's sarcoma after palliative radiotherapy.

  Nature clinical practice. Oncology 20050901

• [Use of thymidine-sparing regimens in first-line therapy and in switches from thymidine analogues].

  Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20050901

• Transgenic expression of the deoxynucleotide carrier causes mitochondrial damage that is enhanced by NRTIs for AIDS.

  Laboratory investigation; a journal of technical methods and pathology 20050801

• Anti-human immunodeficiency virus type 1 activity and resistance profile of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine in vitro.

  Antimicrobial agents and chemotherapy 20050801

• Acanthosis nigricans as an adverse effect of highly active antiretroviral therapy in an adolescent girl with human immunodeficiency virus infection.

  The Pediatric infectious disease journal 20050801

• Nucleoside/nucleotide backbones for the treatment of HIV infection.

  Current opinion in investigational drugs (London, England : 2000) 20050801

• Brain mitochondrial injury in human immunodeficiency virus-seropositive (HIV+) individuals taking nucleoside reverse transcriptase inhibitors.

  Journal of neurovirology 20050801

• Simultaneous analysis of several antiretroviral nucleosides in rat-plasma by high-performance liquid chromatography with UV using acetic acid/hydroxylamine buffer Test of this new volatile medium-pH for HPLC-ESI-MS/MS.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050725

• Optimal suppression of HIV replication by low-dose hydroxyurea through the combination of antiviral and cytostatic ('virostatic') mechanisms.

  AIDS (London, England) 20050722

• Antiviral activity of lamivudine in salvage therapy for multidrug-resistant HIV-1 infection.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050715

• Isocratic, simultaneous normal-phase LC separation of four impurities for a stavudine synthesis control.

  Talanta 20050715

• KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis.

  Antiviral research 20050701

• Stampidine: a selective oculo-genital microbicide.

  The Journal of antimicrobial chemotherapy 20050701

• Microdialysis evaluation of the brain distribution of stavudine following intranasal and intravenous administration to rats.

  Journal of pharmaceutical sciences 20050701

• No pharmacokinetic drug-drug interaction between nevirapine and paclitaxel.

  Anti-cancer drugs 20050701

• Efficacy of highly active antiretroviral therapy in HIV-infected children participating in Thailand's National Access to Antiretroviral Program.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050701

• HIV leucoencephalopathy and TNFalpha expression in neurones.

  Journal of neurology, neurosurgery, and psychiatry 20050701

• Lipoatrophic men 44 months after the diagnosis of lipoatrophy are less lipoatrophic but more hypertensive.

  HIV medicine 20050701

• Lactic acidosis caused by nucleoside analogues.

  The American journal of emergency medicine 20050701

• Relationship between adherence and the development of resistance in antiretroviral-naive, HIV-1-infected patients receiving lopinavir/ritonavir or nelfinavir.

  The Journal of infectious diseases 20050615

• Prevalence of, evolution of, and risk factors for fat atrophy and fat deposition in a cohort of HIV-infected men and women.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050615

• Determination of lamivudine in human plasma by HPLC and its use in bioequivalence studies.

  International journal of pharmaceutics 20050613

• Suppression of multidrug-resistant HIV-1 reverse transcriptase primer unblocking activity by alpha-phosphate-modified thymidine analogues.

  Journal of molecular biology 20050610

• Switch strategies in patients on effective HAART.

  The Journal of antimicrobial chemotherapy 20050601

• Estimating HIV evolutionary pathways and the genetic barrier to drug resistance.

  The Journal of infectious diseases 20050601

• Effects of HIV Q151M-associated multi-drug resistance mutations on the activities of (-)-beta-D-1',3'-dioxolan guanine.

  Antiviral research 20050601

• Incidence of pancreatitis in HIV-1-infected individuals enrolled in 20 adult AIDS clinical trials group studies: lessons learned.

  Journal of acquired immune deficiency syndromes (1999) 20050601

• Lipodystrophy and dyslipidemia among patients taking first-line, World Health Organization-recommended highly active antiretroviral therapy regimens in Western India.

  Journal of acquired immune deficiency syndromes (1999) 20050601

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• Incidence of acute pancreatitis and nucleoside reverse transcriptase inhibitors usage.

  International journal of STD & AIDS 20050601

• Oxygen consumption by cultured human cells is impaired by a nucleoside analogue cocktail that inhibits mitochondrial DNA synthesis.

  Mitochondrion 20050601

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20050601

• Mitochondrial DNA depletion in adipose tissue of HIV-infected patients with peripheral lipoatrophy.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20050501

• Safety of stavudine during pregnancy.

  The Journal of infectious diseases 20050501

• Evaluation of antiretroviral therapy results in a resource-poor setting in Blantyre, Malawi.

  Tropical medicine & international health : TM & IH 20050501

• Better maintained adherence on switching from twice-daily to once-daily therapy for HIV: a 24-week randomized trial of treatment simplification using stavudine prolonged-release capsules.

  HIV medicine 20050501

• The use of a triple nucleoside-nucleotide regimen for nonoccupational HIV post-exposure prophylaxis.

  HIV medicine 20050501

• Protease-mediated enzymatic hydrolysis and activation of aryl phosphoramidate derivatives of stavudine.

  European journal of medicinal chemistry 20050501

• Emerging anti-HIV drugs.

  Expert opinion on emerging drugs 20050501

• Establishment of inherent stability of stavudine and development of a validated stability-indicating HPLC assay method.

  Journal of pharmaceutical and biomedical analysis 20050429

• Switch from ritonavir to indinavir in combination therapy for HIV-1-infected children.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050415

• A one-year clinical trial using didanosine, stavudine and nevirapine for highly active antiretroviral therapy.

  Chinese medical journal 20050405

• Long-term renal safety of tenofovir disoproxil fumarate in antiretroviral-naive HIV-1-infected patients. Data from a double-blind randomized active-controlled multicentre study.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050401

• Predictors of residual viremia in HIV-infected patients successfully treated with efavirenz and lamivudine plus either tenofovir or stavudine.

  The Journal of infectious diseases 20050401

• Enzymatic hydrolysis of stampidine and other stavudine phosphoramidates in the presence of mammalian proteases.

  Bioorganic & medicinal chemistry 20050401

• Comparison of the precision and sensitivity of the Antivirogram and PhenoSense HIV drug susceptibility assays.

  Journal of acquired immune deficiency syndromes (1999) 20050401

• Successful projection of the time course of drug concentration in plasma during a 1-year period from electronically compiled dosing-time data used as input to individually parameterized pharmacokinetic models.

  Journal of clinical pharmacology 20050401

• [Toxic epidermal necrolysis associated with abacavir].

  Enfermedades infecciosas y microbiologia clinica 20050401

• Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: results of a global collaboration.

  PLoS medicine 20050401

• Aplastic anemia in an HIV infected child.

  Indian journal of pediatrics 20050401

• Lowering the dose of hydroxyurea minimizes toxicity and maximizes anti-HIV potency.

  AIDS research and human retroviruses 20050401

• Emtricitabine: a novel nucleoside reverse transcriptase inhibitor.

  Drugs of today (Barcelona, Spain : 1998) 20050401

• The effect of baseline CD4 cell count and HIV-1 viral load on the efficacy and safety of nevirapine or efavirenz-based first-line HAART.

  AIDS (London, England) 20050325

• Hepatic steatosis and antiretroviral drug use among adults coinfected with HIV and hepatitis C virus.

  AIDS (London, England) 20050324

• [Efficacy of anti-HIV treatment and drug-resistance mutations in some parts of China].

  Zhonghua yi xue za zhi 20050323

• Severe hepatotoxicity associated with nevirapine use in HIV-infected subjects.

  The Journal of infectious diseases 20050315

• Stereochemical influence on lipase-mediated hydrolysis and biological activity of stampidine and other stavudine phosphoramidates.

  Bioorganic & medicinal chemistry 20050301

• A combined-formulation tablet of lamivudine/nevirapine/stavudine: bioequivalence compared with concurrent administration of lamivudine, nevirapine, and stavudine in healthy Indian subjects.

  Journal of clinical pharmacology 20050301

• Impact of dyslipidemia associated with Highly Active Antiretroviral Therapy (HAART) on cardiovascular risk and life expectancy.

  The American journal of cardiology 20050301

• Selection of a rare resistance profile in an HIV-1-infected patient exhibiting a failure to an antiretroviral regimen including tenofovir DF.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20050301

• In vitro activity of structurally diverse nucleoside analogs against human immunodeficiency virus type 1 with the K65R mutation in reverse transcriptase.

  Antimicrobial agents and chemotherapy 20050301

• Increased adipocyte apoptosis in lipoatrophy improves within 48 weeks of switching patient therapy from Stavudine to abacavir or zidovudine.

  Journal of acquired immune deficiency syndromes (1999) 20050301

• Contribution of cellular HIV-1 DNA quantification to the efficacy analysis of antiretroviral therapy: a randomized comparison of 2 regimens, including 3 drugs from 2 or 3 classes (TRIANON, ANRS 081).

  Journal of acquired immune deficiency syndromes (1999) 20050301

• Plasma HIV-1 RNA decline within the first two weeks of treatment is comparable for nevirapine, efavirenz, or both drugs combined and is not predictive of long-term virologic efficacy: A 2NN substudy.

  Journal of acquired immune deficiency syndromes (1999) 20050301

• Can we get more HIV-positive tuberculosis patients on antiretroviral treatment in a rural district of Malawi?

  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20050301

• Gender differences in health-related quality of life in patients with HIV/AIDS.

  Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20050301

• The efficacy and adverse effects of GPO-VIR (stavudine+lamivudine+nevirapine) in treatment-naïve adult HIV patients.

  The Southeast Asian journal of tropical medicine and public health 20050301

• Simultaneous determination of the HIV nucleoside analogue reverse transcriptase inhibitors lamivudine, didanosine, stavudine, zidovudine and abacavir in human plasma by reversed phase high performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225

• Sculptra facial treatment: new physician locator.

  AIDS treatment news 20050225

• Synthesis and evaluation of double-prodrugs against HIV. Conjugation of D4T with 6-benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach.

  Journal of medicinal chemistry 20050224

• Loading efficiency of stavudine on polybutylcyanoacrylate and methylmethacrylate-sulfopropylmethacrylate copolymer nanoparticles.

  International journal of pharmaceutics 20050216

• Therapeutic response of HIV-1 subtype C in African patients coinfected with either Mycobacterium tuberculosis or human herpesvirus-8.

  The Journal of infectious diseases 20050201

• Interventions for managing antiretroviral therapy-associated lipoatrophy.

  Current opinion in infectious diseases 20050201

• Body composition and metabolic changes in antiretroviral-naive patients randomized to didanosine and stavudine vs. abacavir and lamivudine.

  Journal of acquired immune deficiency syndromes (1999) 20050201

• Non-paracetamol drug-induced fulminant hepatic failure among adults in Scotland.

  European journal of gastroenterology & hepatology 20050201

• Hyperlactataemia and lactic acidosis in HIV-infected patients receiving antiretroviral therapy.

  Clinical nutrition (Edinburgh, Scotland) 20050201

• Treatment of chronic hepatitis C in human immunodeficiency virus/hepatitis C virus-coinfected patients in the era of pegylated interferon and ribavirin.

  Seminars in liver disease 20050201

• Mycotic brain abscess caused by opportunistic reptile pathogen.

  Emerging infectious diseases 20050201

• Resistance to dual nucleoside reverse-transcriptase inhibitors in children infected with HIV clade A/E.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050115

• Improvements in lipoatrophy, mitochondrial DNA levels and fat apoptosis after replacing stavudine with abacavir or zidovudine.

  AIDS (London, England) 20050103

• Lipoatrophy and mitochondrial DNA assays: see all, know all?

  AIDS (London, England) 20050103

• Modification of the incidence of drug-associated symmetrical peripheral neuropathy by host and disease factors in the HIV outpatient study cohort.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050101

• Metabolic syndrome among HIV-infected patients: prevalence, characteristics, and related factors.

  Diabetes care 20050101

• Drug resistance mutations in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase differentially affect the phosphorolysis-dependent primer unblocking activity in the presence of stavudine and zidovudine and its inhibition by efavirenz.

  Antimicrobial agents and chemotherapy 20050101

• Development and validation of a liquid chromatographic/tandem mass spectrometric assay for the quantitation of nucleoside HIV reverse transcriptase inhibitors in biological matrices.

  Journal of mass spectrometry : JMS 20050101

• Substituting abacavir for hyperlipidemia-associated protease inhibitors in HAART regimens improves fasting lipid profiles, maintains virologic suppression, and simplifies treatment.

  BMC infectious diseases 20050101

• Changes in lipids over twelve months after initiating protease inhibitor therapy among persons treated for HIV/AIDS.

  Lipids in health and disease 20050101

• Molecular strategies to inhibit HIV-1 replication.

  Retrovirology 20050101

• Risk factors for hyperlactataemia in HIV-infected patients, Aquitaine Cohort, 1999--2003.

  Antiviral chemistry & chemotherapy 20050101

• Body fat changes among antiretroviral-naive patients on PI- and NNRTI-based HAART in the Swiss HIV cohort study.

  Antiviral therapy 20050101

• Nevirapine and efavirenz pharmacokinetics and covariate analysis in the 2NN study.

  Antiviral therapy 20050101

• Changes in mitochondrial RNA production in cells treated with nucleoside analogues.

  Antiviral therapy 20050101

• Stavudine entry into cerebrospinal fluid after single and multiple doses in patients infected with human immunodeficiency virus.

  Pharmacotherapy 20050101

• Abacavir, efavirenz, didanosine, with or without hydroxyurea, in HIV-infected adults failing initial nucleoside/protease inhibitor-containing regimens.

  BMC infectious diseases 20050101

• Synthesis of (+/-)-4'-ethynyl and 4'-cyano carbocyclic analogues of stavudine (d4T).

  Nucleosides, nucleotides & nucleic acids 20050101

• Altered adipokine response in murine 3T3-F442A adipocytes treated with protease inhibitors and nucleoside reverse transcriptase inhibitors.

  Antiviral therapy 20050101

• The HIV protease inhibitors nelfinavir and saquinavir, but not a variety of HIV reverse transcriptase inhibitors, adversely affect human proteasome function.

  Antiviral therapy 20050101

• Pharmacokinetics of reduced-dose indinavir/ritonavir 400/100 mg twice daily in HIV-1-infected Thai patients.

  Antiviral therapy 20050101

• Mitochondrial toxicity of nucleoside analogues in primary human lymphocytes.

  Antiviral therapy 20050101

• Field assessment of generic antiretroviral drugs: a prospective cohort study in Cameroon.

  Antiviral therapy 20050101

• In vitro combination studies of tenofovir and other nucleoside analogues with ribavirin against HIV-1.

  Antiviral therapy 20050101

• In vitro anti-HIV potency of stampidine alone and in combination with standard anti-HIV drugs.

  Arzneimittel-Forschung 20050101

• Incidence and risk factors for mitochondrial toxicity in treated HIV/HCV-coinfected patients.

  Antiviral therapy 20050101

• Evaluation of multiple failure time analyses of observational data in patients treated for HIV.

  HIV clinical trials 20050101

• Incidence and risk factors for liver enzyme elevation during highly active antiretroviral therapy in HIV-HCV co-infected patients: results from the Italian EPOKA-MASTER Cohort.

  BMC infectious diseases 20050101

• Cost-effectiveness of models for prevention of vertical HIV transmission - voluntary counseling and testing and choices of drug regimen.

  Cost effectiveness and resource allocation : C/E 20050101

• Are adverse events of nevirapine and efavirenz related to plasma concentrations?

  Antiviral therapy 20050101

• Reverse transcriptase inhibitors alter uncoupling protein-1 and mitochondrial biogenesis in brown adipocytes.

  Antiviral therapy 20050101

• Muscle and liver lactate metabolism in HAART-treated and naive HIV-infected patients: the MITOVIR study.

  Antiviral therapy 20050101

• Total body composition by DXA of 241 HIV-negative men and 162 HIV-infected men: proposal of reference values for defining lipodystrophy.

  Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry 20050101

• [Ester derivatives of nucleoside inhibitors of reverse transcriptase: I. Molecular transport systems for 3'-azido-3'-deoxythymidine and 2',3'-didehydro-3'-deoxythymidine].

  Bioorganicheskaia khimiia 20050101

• Safety and tolerability of nevirapine-based antiretroviral therapy in HIV-infected patients receiving fluconazole for cryptococcal prophylaxis: a retrospective cohort study.

  BMC infectious diseases 20050101

• 4'-Ethynylstavudine (4'-Ed4T) has potent anti-HIV-1 activity with reduced toxicity and shows a unique activity profile against drug-resistant mutants.

  Antiviral chemistry & chemotherapy 20050101

• Nucleoside reverse transcriptase inhibitors, mitochondrial DNA and AIDS therapy.

  Antiviral therapy 20050101

• Mitochondrial studies in HAART-related lipodystrophy: from experimental hypothesis to clinical findings.

  Antiviral therapy 20050101

• Uridine in the prevention and treatment of NRTI-related mitochondrial toxicity.

  Antiviral therapy 20050101

• The effect of long-term storage on measured plasma lactate concentrations and prospective lactate results from a multicenter trial of antiretroviral therapy.

  Clinical chemistry and laboratory medicine 20050101

• Mycobacterial immune reconstitution inflammatory syndrome in HIV-1 infection after antiretroviral therapy is associated with deregulated specific T-cell responses: beneficial effect of IL-2 and GM-CSF immunotherapy.

  Journal of immune based therapies and vaccines 20050101

• Persistence of lipoatrophy after a four-year long interruption of antiretroviral therapy for HIV1 infection: case report.

  BMC infectious diseases 20050101

• Reductions in stavudine dose might ameliorate mitochondrial-associated complications without compromising antiviral activity.

  HIV clinical trials 20050101

• Human immunodeficiency virus type-1 episomal cDNA in semen.

  AIDS research and therapy 20050101

• Cardiac mitochondrial compromise in 1-yr-old Erythrocebus patas monkeys perinatally-exposed to nucleoside reverse transcriptase inhibitors.

  Cardiovascular toxicology 20050101

• [Ester derivatives of nucleoside inhibitors of reverse transcriptase: II. Molecular systems for combined therapy with 3'-azido-3'-deoxythymidine and 2',3'-didehydro-3'-deoxythymidine].

  Bioorganicheskaia khimiia 20050101

• A new approach to the synthesis of 4'-carbon-substituted nucleosides: development of a highly active anti-HIV agent 2', 3'-didehydro-3'-deoxy-4'-ethynylthymidine.

  Nucleosides, nucleotides & nucleic acids 20050101

• Homo and heterodimers of ddI, d4T and AZT: influence of (5'-5') thiolcabonate-carbamate linkage on anti-HIV activity.

  Nucleosides, nucleotides & nucleic acids 20050101

• 'Lock-in' modified cyclosal nucleotides--the second generation of cyclosal prodrugs.

  Nucleosides, nucleotides & nucleic acids 20050101

• Cerebrospinal fluid HIV infection and pleocytosis: relation to systemic infection and antiretroviral treatment.

  BMC infectious diseases 20050101

• First-line antiretroviral therapy in Africa--how evidence-base are our recommendations?

  AIDS reviews 20050101

• Comparison of two once-daily regimens with a regimen consisting of nelfinavir, didanosine, and stavudine in antiretroviral therapy-naïve adults: 48-week results from the Antiretroviral Regimen Evaluation Study (ARES).

  HIV clinical trials 20050101

• Pharmacokinetics of nevirapine: once-daily versus twice-daily dosing in the 2NN study.

  HIV clinical trials 20050101

• Thymidine analogue mutation profiles: factors associated with acquiring specific profiles and their impact on the virological response to therapy.

  Antiviral therapy 20050101

• Letter. In vitro phenotypic susceptibility to nucleoside reverse transcriptase inhibitors of HIV-2 isolates with the Q151M mutation in the reverse transcriptase gene.

  Antiviral therapy 20050101

• Do non-nucleoside reverse transcriptase inhibitors contribute to lipodystrophy?

  Drug safety 20050101

• Sex differences in antiretroviral therapy-associated intolerance and adverse events.

  Drug safety 20050101

• Antiretroviral-therapy-associated lipoatrophy: current status and future directions.

  Sexual health 20050101

• [A study of initial antiretroviral therapy effectiveness, survival and safety in HIV+ patients].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20050101

• Scutellaria baicalensis decreases ritonavir-induced nausea.

  AIDS research and therapy 20050101

• Triple-nucleoside analog antiretroviral therapy: is there still a role in clinical practice? A review.

  MedGenMed : Medscape general medicine 20050101

• Efficacy and safety of indinavir/ritonavir 400/100 mg twice daily plus two nucleoside analogues in treatment-naive HIV-1-infected patients with CD4+ T-cell counts <200 cells/mm3: 96-week outcomes.

  Antiviral therapy 20050101

• Improvement in dyslipidaemia after switching stavudine to tenofovir and replacing protease inhibitors with efavirenz in HIV-infected children.

  Antiviral therapy 20050101

• Synthesis and anti-HIV activity of beta-D-3'-azido-2',3'-unsaturated nucleosides and beta-D-3'-azido-3'-deoxyribofuranosylnucleosides.

  Nucleosides, nucleotides & nucleic acids 20050101

• Changes in body fat measured by DEXA in patients taking different formulations of stavudine.

  HIV clinical trials 20050101

• [In vitro selection and phenotyping of HIV-1 mutants resistant to azidothymidine and didanosine].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20050101

• HPLC analysis of generic antiretroviral drugs purchased in Rwanda.

  Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg 20050101

• Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs.

  Journal of the International AIDS Society 20050101

• Triple-nucleoside analog antiretroviral therapy: is there still a role in clinical practice? A review.

  Journal of the International AIDS Society 20050101

• Cytokine profiles in human immunodeficiency virus-infected children treated with highly active antiretroviral therapy.

  Journal of the International AIDS Society 20050101

• Hypertriglyceridemia in antiretroviral therapy.

  Journal of the International AIDS Society 20050101

• Initiating antiretrovirals in a resource-constrained setting: does one size fit all?

  Journal of the International AIDS Society 20050101

• Frequency of Drug-Resistant Variants of HIV-1 Coexistent With Wild-Type in Treatment-Naive Patients of India.

  Journal of the International AIDS Society 20050101

• Genetic barriers to resistance and impact on clinical response.

  Journal of the International AIDS Society 20050101

• A case-control study of HIV-associated pancreatic abnormalities during HAART era. Focus on emerging risk factors and specific management.

  European journal of medical research 20041222

• Pharmacokinetics and safety of stavudine in HIV-infected pregnant women and their infants: Pediatric AIDS Clinical Trials Group protocol 332.

  The Journal of infectious diseases 20041215

• Upregulatory mechanisms compensate for mitochondrial DNA depletion in asymptomatic individuals receiving stavudine plus didanosine.

  Journal of acquired immune deficiency syndromes (1999) 20041215

• Drug-induced increased mitochondrial biogenesis in a liver biopsy.

  Experimental and molecular pathology 20041201

• Hepatic steatosis and pancreatitis associated with the use of stavudine in a patient with HIV infection.

  AJR. American journal of roentgenology 20041201

• Randomized, controlled trial of therapy interruption in chronic HIV-1 infection.

  PLoS medicine 20041201

• Short communication: benefits in the lipid profile after substitution of abacavir for Stavudine: a 48-week prospective study.

  AIDS research and human retroviruses 20041201

• Antiretroviral drugs with adverse effects on adipocyte lipid metabolism and survival alter the expression and secretion of proinflammatory cytokines and adiponectin in vitro.

  Antiviral therapy 20041201

• Mitochondrial effects of a 24-week course of pegylated-interferon plus ribavirin in asymptomatic HCV/HIV co-infected patients on long-term treatment with didanosine, stavudine or both.

  Antiviral therapy 20041201

• Interaction of nucleoside inhibitors of HIV-1 reverse transcriptase with the concentrative nucleoside transporter-1 (SLC28A1).

  Antiviral therapy 20041201

• Synthesis of 5-alkynylated d4T analogues as potential HIV-1 reverse transcriptase inhibitors.

  Journal of enzyme inhibition and medicinal chemistry 20041201

• Prevalence of genotypic resistance to nucleoside analogues and protease inhibitors in antiretroviral-naive HIV patients in Campania, Italy.

  Journal of chemotherapy (Florence, Italy) 20041201

• A randomized study of emtricitabine and lamivudine in stably suppressed patients with HIV.

  AIDS (London, England) 20041119

• Gynecomastia among HIV-infected patients is associated with hypogonadism: a case-control study.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041115

• CADA, a novel CD4-targeted HIV inhibitor, is synergistic with various anti-HIV drugs in vitro.

  AIDS (London, England) 20041105

• The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro.

  AIDS (London, England) 20041105

• Broad specificity of human phosphoglycerate kinase for antiviral nucleoside analogs.

  Biochemical pharmacology 20041101

• Bioequivalence evaluation of two marketed brands of stavudine 40 mg capsules in healthy human South African volunteers.

  Pharmacological research 20041101

• Neurological complications in AIDS patients: the 1-year retrospective study in Chiang Mai University, Thailand.

  European journal of neurology 20041101

• Acute onset of pancreatitis with concomitant use of tenofovir and didanosine.

  The Annals of pharmacotherapy 20041001

• Tenofovir: new indication. For first-line antiretroviral therapy: wait and see.

  Prescrire international 20041001

• Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1.

  PLoS medicine 20041001

• Quality of life in patients treated with first-line antiretroviral therapy containing nevirapine and/or efavirenz.

  Antiviral therapy 20041001

• Effects of zidovudine, stavudine and beta-aminoisobutyric acid on lipid homeostasis in mice: possible role in human fat wasting.

  Antiviral therapy 20041001

• Binding of anti-HIV drugs to human serum albumin.

  IUBMB life 20041001

• Primer unblocking by HIV-1 reverse transcriptase and resistance to nucleoside RT inhibitors (NRTIs).

  The international journal of biochemistry & cell biology 20040901

• Mitochondrial dysfunction: patient monitoring and toxicity management.

  Journal of acquired immune deficiency syndromes (1999) 20040901

• Safety and antiretroviral effectiveness of concomitant use of rifampicin and efavirenz for antiretroviral-naive patients in India who are coinfected with tuberculosis and HIV-1.

  Journal of acquired immune deficiency syndromes (1999) 20040901

• Assessing the risk of birth defects associated with antiretroviral exposure during pregnancy.

  American journal of obstetrics and gynecology 20040901

• Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance.

  AIDS (London, England) 20040820

• Relative replication fitness of multi-nucleoside analogue-resistant HIV-1 strains bearing a dipeptide insertion in the fingers subdomain of the reverse transcriptase and mutations at codons 67 and 215.

  Virology 20040815

• Nucleoside analogue use before and during highly active antiretroviral therapy and virus load rebound.

  The Journal of infectious diseases 20040815

• Mitochondrial oxidative stress in human hepatoma cells exposed to stavudine.

  Toxicology and applied pharmacology 20040815

• HIV-1 drug resistance in subjects with advanced HIV-1 infection in whom antiretroviral combination therapy is failing: a substudy of AIDS Clinical Trials Group Protocol 388.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040815

• Lack of recurrence of hyperlactatemia in HIV-infected patients switched from stavudine to abacavir or zidovudine.

  Journal of acquired immune deficiency syndromes (1999) 20040801

• A comparative study of the hydrolysis pathways of substituted aryl phosphoramidate versus aryl thiophosphoramidate derivatives of stavudine.

  European journal of medicinal chemistry 20040801

• Occurrence of intracerebral aneurysm in an HIV-infected child: a case report.

  Pediatric neurology 20040801

• Impact of indinavir on the quality of life in patients with advanced HIV infection treated with zidovudine and lamivudine.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040801

• Antiretroviral treatment. HIV infection in adults: better-defined first-line treatment.

  Prescrire international 20040801

• Baseline HIV-1 RNA level and CD4 cell count predict time to loss of virologic response to nelfinavir, but not lopinavir/ritonavir, in antiretroviral therapy-naive patients.

  The Journal of infectious diseases 20040715

• Efficacy and safety of emtricitabine vs stavudine in combination therapy in antiretroviral-naive patients: a randomized trial.

  JAMA 20040714

• Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: a 3-year randomized trial.

  JAMA 20040714

• HIV-associated neuromuscular weakness syndrome.

  AIDS (London, England) 20040702

• Antiretroviral therapy, fat redistribution and hyperlipidaemia in HIV-infected children in Europe.

  AIDS (London, England) 20040702

• Improvement of dyslipidemia in patients switching from stavudine to tenofovir: preliminary results.

  AIDS (London, England) 20040702

• Uncharged AZT and D4T derivatives of phosphonoformic and phosphonoacetic acids as anti-HIV pronucleosides.

  Journal of medicinal chemistry 20040701

• Preparation and pharmacokinetics of 11C labeled stavudine (d4T).

  Nuclear medicine and biology 20040701

• Acquired and inherited lipodystrophies.

  The New England journal of medicine 20040701

• Generic antiretroviral drugs--will they be the answer to HIV in the developing world?

  Lancet (London, England) 20040701

• Effectiveness and safety of a generic fixed-dose combination of nevirapine, stavudine, and lamivudine in HIV-1-infected adults in Cameroon: open-label multicentre trial.

  Lancet (London, England) 20040701

• First-line and second-line antiretroviral therapy.

  Lancet (London, England) 20040701

• Novel benzyl rearrangements in electrospray ionization multistage tandem mass spectra of benzyl 2',3'- didehydro-2',3'-dideoxythymidin-5'-yl H-phosphonate.

  Journal of mass spectrometry : JMS 20040701

• Lack of reduction of thymidine kinase activity in stavudine-treated HIV-infected patients.

  AIDS research and human retroviruses 20040701

• Prognostic factors in lactic acidosis syndrome caused by nucleoside reverse transcriptase inhibitors: report of eight cases and review of the literature.

  AIDS patient care and STDs 20040701

• Mutations and polymorphisms associated with antiretroviral drugs in HIV-1C-infected African patients.

  Antiviral chemistry & chemotherapy 20040701

• Safety and efficacy of a simplified fixed-dose combination of stavudine, lamivudine and nevirapine (GPO-VIR) for the treatment of advanced HIV-infected patients: a 24-week study.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20040701

• Role of mitochondria in HIV lipoatrophy: insight into pathogenesis and potential therapies.

  Mitochondrion 20040701

• Mitochondrial membrane potential and nucleosidic inhibitors of HIV reverse transcriptase: a cytometric approach.

  Mitochondrion 20040701

• Mechanistic explanation to the variable degradation behaviour of stavudine and zidovudine under hydrolytic, oxidative and photolytic conditions.

  Journal of pharmaceutical and biomedical analysis 20040629

• MIV-310 reduces HIV viral load in patients failing multiple antiretroviral therapy: results from a 4-week phase II study.

  AIDS (London, England) 20040618

• Gynecomastia and potent antiretroviral therapy.

  AIDS (London, England) 20040618

• Lipase-mediated stereoselective hydrolysis of stampidine and other phosphoramidate derivatives of stavudine.

  Bioorganic & medicinal chemistry 20040615

• A trial of three antiretroviral regimens in HIV-1-infected children.

  The New England journal of medicine 20040610

• Molecular determinants of multi-nucleoside analogue resistance in HIV-1 reverse transcriptases containing a dipeptide insertion in the fingers subdomain: effect of mutations D67N and T215Y on removal of thymidine nucleotide analogues from blocked DNA primers.

  The Journal of biological chemistry 20040604

• Thrombotic microangiopathy: an atypical cause of acute renal failure in patients with acute pancreatitis.

  Intensive care medicine 20040601

• Emtricitabine: a once-daily nucleoside reverse transcriptase inhibitor.

  The Annals of pharmacotherapy 20040601

• Antiviral drugs in current clinical use.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20040601

• Long-term efficacy and safety of atazanavir with stavudine and lamivudine in patients previously treated with nelfinavir or atazanavir.

  Journal of acquired immune deficiency syndromes (1999) 20040601

• Three-year durability of dual-nucleoside versus triple-nucleoside therapy in a Thai population with HIV infection.

  Journal of acquired immune deficiency syndromes (1999) 20040601

• Stavudine effects on rat pregnancy outcome.

  The journal of obstetrics and gynaecology research 20040601

• Prevalence of lipoatrophy and mitochondrial DNA content of blood and subcutaneous fat in HIV-1-infected patients randomly allocated to zidovudine- or stavudine-based therapy.

  Antiviral therapy 20040601

• 2('),3(')-didehydro-2('),3(')-dideoxynucleosides are degraded to furfuryl alcohol under acidic conditions.

  Bioorganic & medicinal chemistry letters 20040503

• Identification and characterization of the conserved nucleoside-binding sites in the Epstein-Barr virus thymidine kinase.

  The Biochemical journal 20040501

• Rate of thymidine analogue resistance mutation accumulation with zidovudine- or stavudine-based regimens.

  Journal of acquired immune deficiency syndromes (1999) 20040501

• Novel 4'-substituted stavudine analog with improved anti-human immunodeficiency virus activity and decreased cytotoxicity.

  Antimicrobial agents and chemotherapy 20040501

• Stereospecific chemical and enzymatic stability of phosphoramidate triester prodrugs of d4T in vitro.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040501

• 'Lock-in'-cycloSal-pronucleotides - a new generation of chemical Trojan Horses?

  Mini reviews in medicinal chemistry 20040501

• The role of nucleoside reverse transcriptase inhibitors in the fat redistribution syndrome.

  Journal of HIV therapy 20040501

• Reversibility of lipoatrophy in HIV-infected patients 2 years after switching from a thymidine analogue to abacavir: the MITOX Extension Study.

  AIDS (London, England) 20040430

• Beneficial effects of oral uridine in mitochondrial toxicity.

  AIDS (London, England) 20040430

• [Lactic acidosis in HIV-patients--diagnosis and treatment].

  MMW Fortschritte der Medizin 20040426

• Enantioseparation of four cis and trans diastereomers of 2',3'-didehydro-2',3'-dideoxythymidine analogs, by high-performance liquid chromatography and capillary electrophoresis.

  Journal of chromatography. A 20040423

• Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN Study.

  Lancet (London, England) 20040417

• Nucleoside analogues and mitochondrial toxicity.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040415

• Fatal lactic acidosis associated with highly active antiretroviral therapy in patients with advanced human immunodeficiency virus infection in Taiwan.

  International journal of STD & AIDS 20040401

• Pharmacokinetic evaluation and short-term activity of stavudine, nevirapine, and nelfinavir therapy in HIV-1-infected adults.

  Journal of acquired immune deficiency syndromes (1999) 20040401

• Pharmacokinetic characteristics of ritonavir, zidovudine, lamivudine, and stavudine in children with human immunodeficiency virus infection.

  Pharmacotherapy 20040401

• Asymptomatic hyperlactataemia: predictive value, natural history and correlates.

  Antiviral therapy 20040401

• Lamivudine 300 mg in HIV infection: dose change. Once-a-day dosing.

  Prescrire international 20040401

• Suppression of human immunodeficiency virus replication in human brain tissue by nucleoside reverse transcriptase inhibitors.

  Journal of neurovirology 20040401

• Long-term safety and durable antiretroviral activity of lopinavir/ritonavir in treatment-naive patients: 4 year follow-up study.

  AIDS (London, England) 20040326

• The longer the better? Four years of durable, initially boosted protease treatment.

  AIDS (London, England) 20040326

• Efavirenz induces a striking and generalized increase of HDL-cholesterol in HIV-infected patients.

  AIDS (London, England) 20040326

• 'African medicine' and Reye's syndrome.

  Lancet (London, England) 20040313

• Synthesis of stavudine amino acid ester prodrugs with broad-spectrum chemotherapeutic properties for the effective treatment of HIV/AIDS.

  Bioorganic & medicinal chemistry letters 20040308

• Development and validation of a reversed-phase liquid chromatographic method for analysis of D4T (Stavudine) in rat plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040305

• A randomized trial to investigate the recycling of stavudine and didanosine with and without hydroxyurea in salvage therapy (RESTART).

  The Journal of antimicrobial chemotherapy 20040301

• Stampidine is a potential nonspermicidal broad-spectrum anti-human immunodeficiency virus microbicide.

  Fertility and sterility 20040301

• Tenofovir-related nephrotoxicity: case report and review of the literature.

  Pharmacotherapy 20040301

• Phenyl phosphoramidate derivatives of stavudine as anti-HIV agents with potent and selective in-vitro antiviral activity against adenovirus.

  European journal of medicinal chemistry 20040301

• A case of lactic acidosis caused by stavudine in an AIDS patient.

  The Korean journal of internal medicine 20040301

• Q fever endocarditis in HIV-infected patient.

  Emerging infectious diseases 20040301

• Changes in mitochondrial DNA copy number in blood cells from HIV-infected patients undergoing antiretroviral therapy.

  AIDS research and human retroviruses 20040301

• Report from San Francisco: The 11th Conference on Retroviruses and Opportunistic Infections (CROI). Lipodystrophy and metabolic complications.

  The Hopkins HIV report : a bimonthly newsletter for healthcare providers 20040301

• Another emerging event occurring during HIV infection treated with any antiretroviral therapy: frequency and role of gynecomastia.

  Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20040301

• Detection of stavudine concentrations in plasma of HIV-infected patients taking zidovudine.

  AIDS (London, England) 20040220

• Managing HIV lipoatrophy.

  Lancet (London, England) 20040207

• Mitochondrial expression of the human equilibrative nucleoside transporter 1 (hENT1) results in enhanced mitochondrial toxicity of antiviral drugs.

  The Journal of biological chemistry 20040206

• Comparative evaluation of three computerized algorithms for prediction of antiretroviral susceptibility from HIV type 1 genotype.

  The Journal of antimicrobial chemotherapy 20040201

• Low plasma level of adiponectin is associated with stavudine treatment and lipodystrophy in HIV-infected patients.

  Clinical and experimental immunology 20040201

• Newer treatments for HIV in children.

  Current opinion in pediatrics 20040201

• Enantioseparation of new nucleoside analogs, related to d4T and acyclovir, by chiral capillary electrophoresis using highly sulfated beta-cyclodextrins.

  Electrophoresis 20040201

• Depletion of mitochondrial DNA in liver under antiretroviral therapy with didanosine, stavudine, or zalcitabine.

  Hepatology (Baltimore, Md.) 20040201

• Mitochondrial effects of antiretroviral therapies in asymptomatic patients.

  Antiviral therapy 20040201

• Susceptibility of HIV-2, SIV and SHIV to various anti-HIV-1 compounds: implications for treatment and postexposure prophylaxis.

  Antiviral therapy 20040201

• Strategies to decrease viral load rebound, and prevent loss of CD4 and onset of resistance during structured treatment interruptions.

  Antiviral therapy 20040201

• Monitoring of didanosine and stavudine intracellular trisphosphorylated anabolite concentrations in HIV-infected patients.

  AIDS (London, England) 20040123

• Highly active antiretroviral therapy started in infants under 3 months of age: 72-week follow-up for CD4 cell count, viral load and drug resistance outcome.

  AIDS (London, England) 20040123

• Peripheral oedema and high arterial blood flow as a complication of antiretroviral therapy.

  AIDS (London, England) 20040123

• Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine: the results of the TARHEEL study.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040115

• Once-daily versus twice-daily lopinavir/ritonavir in antiretroviral-naive HIV-positive patients: a 48-week randomized clinical trial.

  The Journal of infectious diseases 20040115

• Liquid chromatographic-tandem mass spectrometric assay for the simultaneous determination of didanosine and stavudine in human plasma, bronchoalveolar lavage fluid, alveolar cells, peripheral blood mononuclear cells, seminal plasma, cerebrospinal fluid and tonsil tissue.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040105

• Thymidine analogue reverse transcriptase inhibitors resistance mutations profiles and association to other nucleoside reverse transcriptase inhibitors resistance mutations observed in the context of virological failure.

  Journal of medical virology 20040101

• Thymidine analogue mutations in antiretroviral-naive HIV-1 patients on triple therapy including either zidovudine or stavudine.

  The Journal of antimicrobial chemotherapy 20040101

• Serum L-lactate and pyruvate in HIV-infected patients with and without presumed NRTI-related adverse events compared to healthy volunteers.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20040101

• Emtricitabine: a new nucleoside analogue for once-daily antiretroviral therapy.

  Expert opinion on investigational drugs 20040101

• Incidence of resistance in a double-blind study comparing lopinavir/ritonavir plus stavudine and lamivudine to nelfinavir plus stavudine and lamivudine.

  The Journal of infectious diseases 20040101

• Novel mechanism of enhanced nociception in a model of AIDS therapy-induced painful peripheral neuropathy in the rat.

  Pain 20040101

• Stampidine prevents mortality in an experimental mouse model of viral hemorrhagic fever caused by lassa virus.

  BMC infectious diseases 20040101

• Synthesis and electrospray ionization mass spectra of AZT/d4T boranophosphates.

  Rapid communications in mass spectrometry : RCM 20040101

• Cyclosal-pronucleotides--development of first and second generation chemical trojan horses for antiviral chemotherapy.

  Frontiers in bioscience : a journal and virtual library 20040101

• In vitro activity of stampidine against primary clinical human immunodeficiency virus isolates.

  Arzneimittel-Forschung 20040101

• Can the peripheral blood monocyte count be used as a marker of CSF resistance to antiretroviral drugs?

  Journal of neurovirology 20040101

• Changes in hematologic parameters and efficacy of thymidine analogue-based, highly active antiretroviral therapy: a meta-analysis of six prospective, randomized, comparative studies.

  Clinical therapeutics 20040101

• Long-term efficacy of a protease inhibitor-sparing, nucleoside reverse transcriptase inhibitor-limiting antiretroviral regimen with nevirapine, lamivudine, and reduced standard stavudine dosage.

  HIV clinical trials 20040101

• Disease progression in HIV-infected patients treated with stavudine vs. zidovudine.

  Journal of clinical epidemiology 20040101

• WHO hopes 3-by-5 plan will reverse Africa's HIV/AIDS epidemic.

  Bulletin of the World Health Organization 20040101

• Bis-ketol nucleoside triesters as prodrugs of the antiviral nucleoside triphosphate analogues of 3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine.

  Nucleosides, nucleotides & nucleic acids 20040101

• Body composition changes in 308 Norwegian HIV-positive patients.

  Scandinavian journal of infectious diseases 20040101

• K65R, TAMs and tenofovir.

  AIDS reviews 20040101

• Correction: Stampidine prevents mortality in an experimental mouse model of viral hemorrhagic fever caused by lassa virus.

  BMC infectious diseases 20040101

• Synthesis and anti-HIV activity of 4'-cyano-2',3'-didehydro-3'-deoxythymidine.

  Nucleosides, nucleotides & nucleic acids 20040101

• Chemoenzymatic syntheses of homo- and heterodimers of AZT and d4T, and evaluation of their anti-HIV activity.

  Nucleosides, nucleotides & nucleic acids 20040101

• [Outcome of hyperlactatemia and lipodystrophy syndromes in patients infected with human immunodeficiency virus].

  Annales de biologie clinique 20040101

• Diagnosis and management of body morphology changes and lipid abnormalities associated with HIV Infection and its therapies.

  Topics in HIV medicine : a publication of the International AIDS Society, USA 20040101

• Hepatitis B virus variants in an HIV-HBV co-infected patient at different periods of antiretroviral treatment with and without lamivudine.

  BMC infectious diseases 20040101

• Changes in thrombolytic and inflammatory markers after initiation of indinavir- or amprenavir-based antiretroviral therapy.

  Cardiovascular toxicology 20040101

• Progression of lipodystrophy (LD) with continued thymidine analogue usage: long-term follow-up from a randomized clinical trial (the PIILR study).

  HIV clinical trials 20040101

• Antiretrovirals, Part II: focus on non-protease inhibitor antiretrovirals (NRTIs, NNRTIs, and fusion inhibitors).

  Psychosomatics 20040101

• Spectrum of clinical disease in a series of 135 hospitalised HIV-infected patients from north India.

  BMC infectious diseases 20040101

• Cost-effectiveness of lopinavir/ritonavir versus nelfinavir as the first-line highly active antiretroviral therapy regimen for HIV infection.

  HIV clinical trials 20040101

• Pharmacokinetics of antiretrovirals in pregnant women.

  Clinical pharmacokinetics 20040101

• The unmasking of Pneumocystis jiroveci pneumonia during reversal of immunosuppression: case reports and literature review.

  BMC infectious diseases 20040101

• Synthesis, in vitro anticancer evaluation, and interference with cell cycle progression of N-phosphoamino acid esters of zidovudine and stavudine.

  Nucleosides, nucleotides & nucleic acids 20040101

• Synthesis and antiviral evaluation of D4T analogues with a spacer arm between glucidic and base moieties.

  Nucleosides, nucleotides & nucleic acids 20040101

• Efficacy and safety of abacavir plus lamivudine versus didanosine plus stavudine when combined with a protease inhibitor, a nonnucleoside reverse transcriptase inhibitor, or both in HIV-1 positive antiretroviral-naive persons.

  HIV clinical trials 20040101

• [Lipodystrophy in HIV infected children].

  Medycyna wieku rozwojowego 20040101

• Synthesis of carbocyclic analogues of 4'-ethynyl- and 4'-cyano-d4T.

  Nucleic acids symposium series (2004) 20040101

• An alternative method suitable for a large scale synthesis of 4'-ethynyl-2',3'-didehydro-3'-deoxythymidine.

  Nucleic acids symposium series (2004) 20040101

• Toxicity of nucleoside analogues used to treat AIDS and the selectivity of the mitochondrial DNA polymerase.

  Biochemistry 20031223

• 1,3-dihydrobenzo[c]furan nucleoside analogues: additional studies of the thymine derivative.

  Bioorganic & medicinal chemistry letters 20031215

• Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection.

  The New England journal of medicine 20031211

• Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection.

  The New England journal of medicine 20031211

• Dose-ranging, randomized, clinical trial of atazanavir with lamivudine and stavudine in antiretroviral-naive subjects: 48-week results.

  AIDS (London, England) 20031205

• Development and evaluation of a thermoreversible ovule formulation of stampidine, a novel nonspermicidal broad-spectrum anti-human immunodeficiency virus microbicide.

  Biology of reproduction 20031201

• Stereoselective and concentration-dependent polarized epithelial permeability of a series of phosphoramidate triester prodrugs of d4T: an in vitro study in Caco-2 and Madin-Darby canine kidney cell monolayers.

  The Journal of pharmacology and experimental therapeutics 20031201

• Efficacy and safety of ritonavir/indinavir 100/400 mg twice daily in combination with two nucleoside analogues in antiretroviral treatment-naive HIV-infected individuals.

  Antiviral therapy 20031201

• Contribution of nucleoside-analogue reverse transcriptase inhibitor therapy to lipoatrophy from the population to the cellular level.

  Antiviral therapy 20031201

• The continuing evolution of HIV therapy.

  The AIDS reader 20031201

• Hair loss in an HIV-1 infected woman receiving lopinavir plus ritonavir therapy as first line HAART.

  Dermatology online journal 20031201

• Safety and efficacy of switching to alternative nucleoside analogues following symptomatic hyperlactatemia and lactic acidosis.

  AIDS (London, England) 20031121

• Synthesis of a highly active new anti-HIV agent 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine.

  Bioorganic & medicinal chemistry letters 20031103

• Mitochondrial and metabolic effects of nucleoside reverse transcriptase inhibitors (NRTIs) in mice receiving one of five single- and three dual-NRTI treatments.

  Antimicrobial agents and chemotherapy 20031101

• Molecular characterization of thymidine kinase from Ureaplasma urealyticum: nucleoside analogues as potent inhibitors of mycoplasma growth.

  Molecular microbiology 20031101

• Host factors may be more important than choice of antiretrovirals in the development of lipoatrophy.

  The AIDS reader 20031101

• Risk factors for lipodystrophy in the CISAI cohort.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20031101

• Failures of 1 week on, 1 week off antiretroviral therapies in a randomized trial.

  AIDS (London, England) 20031017

• [Interaction between methadone and antiretrovirals (stavudine, indinavir, ritonavir, nevirapine)].

  Medicina clinica 20031004

• Hydroxyurea transport across the blood-brain and blood-cerebrospinal fluid barriers of the guinea-pig.

  Journal of neurochemistry 20031001

• Tenofovir disoproxil fumarate.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20031001

• Broad nucleoside reverse-transcriptase inhibitor cross-resistance in human immunodeficiency virus type 1 clinical isolates.

  The Journal of infectious diseases 20031001

• The prevalence of reduced zidovudine susceptibility in zidovudine-naive, antiretroviral-experienced HIV-1-infected patients.

  HIV medicine 20031001

• Matched case-control study to evaluate risk factors for hyperlactataemia in HIV patients on antiretroviral therapy.

  HIV medicine 20031001

• Fatal lactic acidosis during antiretroviral therapy.

  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20031001

• The reassurance of experience.

  International journal of STD & AIDS 20031001

• Intracellular disposition and metabolic effects of zidovudine, stavudine and four protease inhibitors in cultured adipocytes.

  Antiviral therapy 20031001

• Uridine abrogates mitochondrial toxicity related to nucleoside analogue reverse transcriptase inhibitors in HepG2 cells.

  Antiviral therapy 20031001

• Evaluation of a didanosin-containing regimen including genotypic resistance testing: an open-label, multicenter study.

  European journal of medical research 20030929

• Low efficacy and high frequency of adverse events in a randomized trial of the triple nucleoside regimen abacavir, stavudine and didanosine.

  AIDS (London, England) 20030926

• Thailand's do-it-yourself therapy.

  Science (New York, N.Y.) 20030919

• Nucleoside analogue mutations and Q151M in HIV-1 subtype A/E infection treated with nucleoside reverse transcriptase inhibitors.

  AIDS (London, England) 20030905

• Stavudine or indinavir-containing regimens are associated with an increased risk of diabetes mellitus in HIV-infected individuals.

  AIDS (London, England) 20030905

• Effect of transport inhibitors and additional anti-HIV drugs on the movement of lamivudine (3TC) across the guinea pig brain barriers.

  The Journal of pharmacology and experimental therapeutics 20030901

• Factors associated with mitochondrial dysfunction in circulating peripheral blood lymphocytes from HIV-infected people.

  Journal of acquired immune deficiency syndromes (1999) 20030901

• Contraindicated antiretroviral drug combinations.

  New Jersey medicine : the journal of the Medical Society of New Jersey 20030901

• Efficacy and durability of nevirapine in antiretroviral drug näive patients.

  Journal of acquired immune deficiency syndromes (1999) 20030901

• Mitochondrial toxicity in the era of HAART: evaluating venous lactate and peripheral blood mitochondrial DNA in HIV-infected patients taking antiretroviral therapy.

  Journal of acquired immune deficiency syndromes (1999) 20030901

• Rapidly progressive human herpesvirus 8-associated solid anaplastic lymphoma in a patient with AIDS--associated Kaposi sarcoma.

  Leukemia & lymphoma 20030901

• Nucleoside reverse transcriptase inhibitor usage and the incidence of peripheral neuropathy in HIV/AIDS patients.

  Antiviral chemistry & chemotherapy 20030901

• Hope for South Africa--at last.

  Lancet (London, England) 20030816

• Increased prevalence of hypothyroidism among human immunodeficiency virus-infected patients: a need for screening.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030815

• Pancreatitis in an HIV-infected person on a tenofovir, didanosine and stavudine containing highly active antiretroviral treatment.

  The Journal of infection 20030801

• Quantitation of blood lymphocyte mitochondrial DNA for the monitoring of antiretroviral drug-induced mitochondrial DNA depletion.

  Journal of acquired immune deficiency syndromes (1999) 20030801

• Evolution of lipid abnormalities in patients switched from stavudine- to tenofovir-containing regimens.

  Journal of acquired immune deficiency syndromes (1999) 20030801

• Incidence of liver toxicity in hiv-infected patients receiving isolated dual nucleoside analogue antitretroviral therapy.

  Journal of acquired immune deficiency syndromes (1999) 20030801

• Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors.

  The Journal of infectious diseases 20030801

• Lactic acidosis related to nucleoside therapy in HIV-infected patients.

  Expert opinion on pharmacotherapy 20030801

• Lactic acidosis in HIV infected patients: a systematic review of published cases.

  Sexually transmitted infections 20030801

• A strategy for liquid chromatography/tandem mass spectrometric assays of intracellular drugs: application to the validation of the triphosphorylated anabolite of antiretrovirals in peripheral blood mononuclear cells.

  Journal of mass spectrometry : JMS 20030801

• Increased mitochondrial DNA content in peripheral blood lymphocytes from HIV-infected patients with lipodystrophy.

  Antiviral therapy 20030801

• Mitochondrial proliferation, DNA depletion and adipocyte differentiation in subcutaneous adipose tissue of HIV-positive HAART recipients.

  Antiviral therapy 20030801

• Correlates of risk of adipose tissue alterations and their modifications over time in HIV-1-infected women treated with antiretroviral therapy.

  Antiviral therapy 20030801

• [A short-term trial of Didanosine, stavudine, and nevirapine combination therapy for human immunodeficiency virus infection].

  Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20030801

• A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude.

  Journal of medicinal chemistry 20030717

• Comparison between rules-based human immunodeficiency virus type 1 genotype interpretations and real or virtual phenotype: concordance analysis and correlation with clinical outcome in heavily treated patients.

  The Journal of infectious diseases 20030715

• Alternation of antiretroviral drug regimens for HIV infection. A randomized, controlled trial.

  Annals of internal medicine 20030715

• Simultaneous determination of six HIV nucleoside analogue reverse transcriptase inhibitors and nevirapine by liquid chromatography with ultraviolet absorbance detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030705

• Use of HIV-1 reverse transcriptase recovered from human plasma for phenotypic drug susceptibility testing.

  AIDS (London, England) 20030704

• Choroid plexus controls brain availability of anti-HIV nucleoside analogs via pharmacologically inhibitable organic anion transporters.

  AIDS (London, England) 20030704

• Lactate levels in children with HIV/AIDS on highly active antiretroviral therapy.

  AIDS (London, England) 20030704

• Nevirapine-selected mutations Y181I/C of HIV-1 reverse transcriptase confer cross-resistance to stavudine.

  AIDS (London, England) 20030704

• Frequency, risk factors, and outcome of hyperlactatemia in HIV-positive persons: implications for the management of treated patients.

  Clinical chemistry 20030701

• Intermittent administration of high-dose stavudine to nucleoside-experienced individuals infected with HIV-1.

  Journal of acquired immune deficiency syndromes (1999) 20030701

• Fatal lactic acidosis and mimicking Guillain-Barré syndrome in an adolescent with human immunodeficiency virus infection.

  The Pediatric infectious disease journal 20030701

• Fatal lactic acidosis and pancreatitis associated with ribavirin and didanosine therapy.

  The AIDS reader 20030701

• Antiretroviral therapy in HIV-2-infected patients: changes in plasma viral load, CD4+ cell counts, and drug resistance profiles of patients treated in Abidjan, Côte d'Ivoire.

  AIDS (London, England) 20030701

• Deoxyribonucleoside 2'- or 3'-mixed disulfides: prodrugs to target ribonucleotide reductase and/or to inhibit HIV reverse transcription.

  Journal of medicinal chemistry 20030619

• The role of 2',3'-unsaturation on the antiviral activity of anti-HIV nucleosides against 3TC-resistant mutant (M184V).

  Bioorganic & medicinal chemistry letters 20030616

• Variable prediction of antiretroviral treatment outcome by different systems for interpreting genotypic human immunodeficiency virus type 1 drug resistance.

  The Journal of infectious diseases 20030615

• Mitochondrial:nuclear DNA ratios in peripheral blood cells from human immunodeficiency virus (HIV)-infected patients who received selected HIV antiretroviral drug regimens.

  The Journal of infectious diseases 20030615

• Serum lipids, glucose homeostasis and abdominal adipose tissue distribution in protease inhibitor-treated and naive HIV-infected children.

  AIDS (London, England) 20030613

• Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy.

  AIDS (London, England) 20030613

• Latrogenic nephrogenic diabetes insipidus.

  AIDS (London, England) 20030613

• Reversible nucleoside analogue-associated lactic acidosis despite a prolonged course.

  Intensive care medicine 20030601

• Mechanism of inhibition of T-acute lymphoblastic leukemia cells by PNP inhibitor--BCX-1777.

  International immunopharmacology 20030601

• HPLC and mass spectrometry analysis of the enzymatic hydrolysis of anti-HIV pronucleotide diastereomers.

  Bioorganic chemistry 20030601

• Fat distribution and metabolic abnormalities in HIV-infected patients on first combination antiretroviral therapy including stavudine or zidovudine: role of physical activity as a protective factor.

  Antiviral therapy 20030601

• Comparison of nine resistance interpretation systems for HIV-1 genotyping.

  Antiviral therapy 20030601

• Structural determinants in human DNA polymerase gamma account for mitochondrial toxicity from nucleoside analogs.

  Journal of molecular biology 20030523

• Interferon-ribavirin in association with stavudine has no impact on plasma human immunodeficiency virus (HIV) type 1 level in patients coinfected with HIV and hepatitis C virus: a CORIST-ANRS HC1 trial.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030515

• Risk factors for lactic acidosis in HIV-infected patients treated with nucleoside reverse-transcriptase inhibitors: a case-control study.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030515

• Miller Fisher variant of Guillain-Barré syndrome associated with lactic acidosis and stavudine therapy.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030515

• Nevirapine resistance mutation at codon 181 of the HIV-1 reverse transcriptase confers stavudine resistance by increasing nucleotide substrate discrimination and phosphorolytic activity.

  The Journal of biological chemistry 20030502

• Prospective evaluation of the effects of antiretroviral therapy on body composition in HIV-1-infected men starting therapy.

  AIDS (London, England) 20030502

• A randomized trial to study first-line combination therapy with or without a protease inhibitor in HIV-1-infected patients.

  AIDS (London, England) 20030502

• Lactate concentrations distinguish between nucleoside neuropathy and HIV neuropathy.

  AIDS (London, England) 20030502

• APHS can act synergically with clinically available HIV-1 reverse transcriptase and protease inhibitors and is active against several drug-resistant HIV-1 strains in vitro.

  The Journal of antimicrobial chemotherapy 20030501

• A novel genetic pathway of human immunodeficiency virus type 1 resistance to stavudine mediated by the K65R mutation.

  Journal of virology 20030501

• Site-specific differences in the action of NRTI drugs on adipose tissue incubated in vitro with lymphoid cells, and their interaction with dietary lipids.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030501

• Extended treatment with tenofovir disoproxil fumarate in treatment-experienced HIV-1-infected patients: genotypic, phenotypic, and rebound analyses.

  Journal of acquired immune deficiency syndromes (1999) 20030501

• A 48-week, randomized, open-label comparison of three abacavir-based substitution approaches in the management of dyslipidemia and peripheral lipoatrophy.

  Journal of acquired immune deficiency syndromes (1999) 20030501

• Randomized, controlled, 48-week study of switching stavudine and/or protease inhibitors to combivir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients.

  Journal of acquired immune deficiency syndromes (1999) 20030501

• Hydroxyurea in combination with didanosine and stavudine in antiretroviral-experienced HIV-infected subjects with a review of the literature.

  International journal of STD & AIDS 20030501

• [Observational study on the efficacy of the application of two classical regimens of triple antiretroviral therapy].

  Anales de medicina interna (Madrid, Spain : 1984) 20030501

• Nevirapine-based fixed-dose combination ARVs.

  GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies 20030501

• [Long-term tolerance. Preventing lipoatrophy].

  MMW Fortschritte der Medizin 20030428

• [Lipid profile and body fat--significant 'side effect' of antiretroviral therapy. Tenofovir: favorable profile of adverse effects].

  MMW Fortschritte der Medizin 20030428

• Replacing stavudine by abacavir reduces lactate levels and may improve lipoatrophy.

  AIDS (London, England) 20030411

• Body habitus changes related to lipodystrophy.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030401

• Interactions of 1263W94 with other antiviral agents in inhibition of human cytomegalovirus replication.

  Antimicrobial agents and chemotherapy 20030401

• Nucleotide analogue binding, catalysis and primer unblocking in the mechanisms of HIV-1 reverse transcriptase-mediated resistance to nucleoside analogues.

  Antiviral therapy 20030401

• K65R with and without S68: a new resistance profile in vivo detected in most patients failing abacavir, didanosine and stavudine.

  Antiviral therapy 20030401

• A new sensitive cartridge-RIA method for determination of stavudine (D4T) triphosphate in human cells in vivo.

  Antiviral research 20030401

• [Measuring the HIV viral load with LCx (Abbott): importance for the therapeutic follow-up of 3 patients infected by type O HIV].

  Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 20030401

• Diffuse ulcerations due to disseminated histoplasmosis in a patient with HIV.

  Journal of drugs in dermatology : JDD 20030401

• Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds.

  Biochemistry 20030311

• Significant levels of intracellular stavudine triphosphate are found in HIV-infected zidovudine-treated patients.

  AIDS (London, England) 20030307

• Accumulation of mitochondrial DNA mutations in human immunodeficiency virus-infected patients treated with nucleoside-analogue reverse-transcriptase inhibitors.

  American journal of human genetics 20030301

• Forty-eight-week evaluation of lopinavir/ritonavir, a new protease inhibitor, in human immunodeficiency virus-infected children.

  The Pediatric infectious disease journal 20030301

• It's time to face the Zerit problem.

  GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies 20030301

• Acute hepatic failure and lactate acidosis associated with antiretroviral treatment for HIV.

  Wiener klinische Wochenschrift 20030227

• Evaluating dissolution profiles of an anti-HIV agent using ANOVA and non-linear regression models in JMP software.

  International journal of pharmaceutics 20030218

• Toward the development of a virus-cell-based assay for the discovery of novel compounds against human immunodeficiency virus type 1.

  Antimicrobial agents and chemotherapy 20030201

• Mitochondrial disruption and apoptosis in lymphocytes of an HIV infected patient affected by lactic acidosis after treatment with highly active antiretroviral therapy.

  Journal of clinical pathology 20030201

• The role of observational data in monitoring trends in antiretroviral treatment and HIV disease stage: results from the Australian HIV observational database.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20030201

• [Antiretrovirals].

  Nihon rinsho. Japanese journal of clinical medicine 20030201

• AIDS-associated diarrhea and wasting in Northeast Brazil is associated with subtherapeutic plasma levels of antiretroviral medications and with both bovine and human subtypes of Cryptosporidium parvum.

  The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20030201

• Thymidine analogue-sparing highly active antiretroviral therapy (HAART).

  Journal of HIV therapy 20030201

• Case report: nucleoside analogue-induced lactic acidosis in the third trimester of pregnancy.

  AIDS (London, England) 20030124

• Symptomatic hyperlactatemia in an HIV-positive patient: a case report and discussion.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030121

• [Fatty liver and increased serum lactate in a woman with HIV].

  Deutsche medizinische Wochenschrift (1946) 20030117

• Results of a phase 2 clinical trial at 48 weeks (AI424-007): a dose-ranging, safety, and efficacy comparative trial of atazanavir at three doses in combination with didanosine and stavudine in antiretroviral-naive subjects.

  Journal of acquired immune deficiency syndromes (1999) 20030101

• Tenofovir: a nucleotide analog for the management of human immunodeficiency virus infection.

  Pharmacotherapy 20030101

• Prevalence, risk factors and outcome of hyperlactataemia in HIV-infected patients.

  HIV medicine 20030101

• Discrepant results in the interpretation of HIV-1 drug-resistance genotypic data among widely used algorithms.

  HIV medicine 20030101

• Pharmacokinetics of nelfinavir and its active metabolite, hydroxy-tert-butylamide, in infants perinatally infected with human immunodeficiency virus type 1.

  The Pediatric infectious disease journal 20030101

• Double 'd' drug danger.

  The AIDS reader 20030101

• First-line therapy and mitochondrial damage: different nucleosides, different findings.

  HIV clinical trials 20030101

• Multiple relapses of human cytomegalovirus retinitis during HAART in an AIDS patient with reconstitution of CD4+ T cell count in the absence of HCMV-specific CD4+ T cell response.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20030101

• Metabolic acidosis and hepatic steatosis in two HIV-infected patients on stavudine (d4T) treatment.

  Archives of medical research 20030101

• [Severe lactic acidosis in HIV-infected patients treated with nucleosidic reverse transcriptase analogs: a report of 9 cases].

  La Revue de medecine interne 20030101

• In vitro activity of potential anti-poxvirus agents.

  Antiviral research 20030101

• New questions about an old combination--ddI + d4T.

  Project Inform perspective 20030101

• New uses for tenofovir: more questions about d4T.

  Project Inform perspective 20030101

• Prevalence of genotypic HIV-1 drug resistance in Thailand, 2002.

  Annals of clinical microbiology and antimicrobials 20030101

• Variable virological outcomes according to the center providing antiretroviral therapy within the PharmAdapt clinical trial.

  HIV clinical trials 20030101

• Cytopathologic findings in breast masses in men with HIV infection.

  Acta cytologica 20030101

• Natural history of hyperlactataemia in human immunodeficiency virus-1-infected patients during highly active antiretroviral therapy.

  Scandinavian journal of infectious diseases 20030101

• Tenofovir drug interactions: ddI and d4T.

  TreatmentUpdate 20030101

• Self-reported health-related quality of life in persons with HIV infection: results from a multi-site interview project.

  Health and quality of life outcomes 20030101

• HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset).

  Antiviral chemistry & chemotherapy 20030101

• Bench-to-bedside review: severe lactic acidosis in HIV patients treated with nucleoside analogue reverse transcriptase inhibitors.

  Critical care (London, England) 20030101

• Hydroxyurea in the treatment of HIV infection: clinical efficacy and safety concerns.

  Drug safety 20030101

• Could antioxidant supplementation reduce antiretroviral therapy-induced chronic stable hyperlactatemia?

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20030101

• Determination of stavudine in human serum by on-line solid-phase extraction coupled to high-performance liquid chromatography with electrospray ionization tandem mass spectrometry: application to a bioequivalence study.

  Rapid communications in mass spectrometry : RCM 20030101

• Toxicity and pharmacokinetics of stampidine in mice and rats.

  Arzneimittel-Forschung 20030101

• Stavudine in the face of cross-resistance between HIV-1 nucleoside reverse transcriptase inhibitors: a review.

  AIDS reviews 20030101

• Tenofovir disoproxil fumarate.

  Drugs 20030101

• Indinavir did not further increase mean triglyceride levels in HIV-infected patients treated with nucleoside reverse transcriptase inhibitors: an analysis of three randomized clinical trials.

  Pharmacoepidemiology and drug safety 20030101

• Atazanavir.

  Drugs 20030101

• Hyperlactataemia during antiretroviral therapy: incidences, clinical data and treatment.

  Therapie 20030101

• An unusual presentation of Castleman's disease:a case report.

  BMC infectious diseases 20030101

• Recommendations for postexposure prophylaxis of operating room personnel and patients exposed to bloodborne diseases.

  Journal of long-term effects of medical implants 20030101

• [Decrease of HIV-1 replicative capacity after serial passage in MT-4 cells under conditions of the combined antiretroviral therapy].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

• Study of different substituted cyclic and acyclic benzylpronucleotides of d4T relative to their hydrolytic stability and antiviral activity.

  Nucleosides, nucleotides & nucleic acids 20030101

• d4TMP delivery from 7-substituted cycloSal-d4TMPs.

  Nucleosides, nucleotides & nucleic acids 20030101

• Synthesis of new homo and heterodimers of 2',3'-dideoxyinosine (ddI) using ester linkages.

  Nucleosides, nucleotides & nucleic acids 20030101

• Synthesis, stability, and biological evaluation of 1,3-dihydrobenzo[c]furan analogue of d4T and its SATE pronucleotide.

  Nucleosides, nucleotides & nucleic acids 20030101

• Phosphorodiamides as prodrugs for antiviral nucleosides.

  Nucleosides, nucleotides & nucleic acids 20030101

• New lipophilic derivatives of AZT and d4T 5'-phosphonates.

  Nucleosides, nucleotides & nucleic acids 20030101

• In vitro study of resistance-associated genotypic mutations to nucleoside analogs.

  Nucleosides, nucleotides & nucleic acids 20030101

• Three- or four- versus two-drug antiretroviral maintenance regimens for HIV infection.

  The Cochrane database of systematic reviews 20030101

• Emtricitabine: an antiretroviral agent for HIV infection.

  Drugs 20030101

• Recurrent pneumococcal meningitis in a splenectomised HIV-infected patient.

  Annals of clinical microbiology and antimicrobials 20030101

• Pharmacokinetics of stavudine by oral administration to healthy Mexican volunteers.

  Proceedings of the Western Pharmacology Society 20030101

• Body habitus changes, metabolic abnormalities, osteopenia and cardiovascular risk in patients treated for human immunodeficiency virus infection.

  Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna 20030101

• A Comparison of the Therapeutic Plan Costs in the Treatment of HIV-Positive Patients.

  Clinical drug investigation 20030101

• Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine or stavudine, each in combination with lamivudine and indinavir.

  Journal of acquired immune deficiency syndromes (1999) 20021215

• Open-label study of a twice-daily indinavir 800-mg/ritonavir 100-mg regimen in protease inhibitor-naive HIV-infected adults.

  Journal of acquired immune deficiency syndromes (1999) 20021215

• Increased risk of lipoatrophy under stavudine in HIV-1-infected patients: results of a substudy from a comparative trial.

  AIDS (London, England) 20021206

• Thymidine analogue withdrawal for lipoatrophic patients on protease-sparing therapy improves lipoatrophy but compromises antiviral control: the PIILR extension study.

  AIDS (London, England) 20021206

• Nucleoside reverse transcriptase inhibitors impair endothelium-dependent relaxation by increasing superoxide.

  American journal of physiology. Heart and circulatory physiology 20021201

• Metabolism of stavudine-5'-[p-bromophenyl methoxyalaninyl phosphate], stampidine, in mice, dogs, and cats.

  Drug metabolism and disposition: the biological fate of chemicals 20021201

• Antiviral activity of enteric-coated didanosine, stavudine, and nelfinavir versus zidovudine plus lamivudine and nelfinavir.

  Journal of acquired immune deficiency syndromes (1999) 20021201

• Random venous lactate levels among HIV-positive patients on antiretroviral therapy.

  Journal of acquired immune deficiency syndromes (1999) 20021201

• Incidence of adipose tissue alterations in first-line antiretroviral therapy: the LipoICoNa Study.

  Archives of internal medicine 20021201

• Peripheral neuropathy in patients with HIV infection: consider dual pathology.

  Sexually transmitted infections 20021201

• Genotypic and phenotypic resistance patterns in early-stage HIV-1-infected patients failing initial therapy with stavudine, didanosine and nevirapine.

  Antiviral therapy 20021201

• Venous and arterial blood lactate in HIV-infected patients.

  Antiviral therapy 20021201

• Chronic cough induced by abacavir apart from a context of hypersensitivity.

  Allergie et immunologie 20021201

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20021201

• Five new drugs enter the homestretch.

  GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies 20021201

• Switching effective antiretroviral therapy: a review.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20021115

• Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors.

  AIDS (London, England) 20021108

• New anti-HIV agents and targets.

  Medicinal research reviews 20021101

• Stampidine is a potent inhibitor of Zidovudine- and nucleoside analog reverse transcriptase inhibitor-resistant primary clinical human immunodeficiency virus type 1 isolates with thymidine analog mutations.

  Antimicrobial agents and chemotherapy 20021101

• Nevirapine or lamivudine plus stavudine and indinavir: examples of 2-class versus 3-class regimens for the treatment of human immunodeficiency virus type 1.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20021101

• Mean cell volume (MCV) changes in HIV-positive patients taking nucleoside reverse transcriptase inhibitors (NRTIs): a surrogate marker for adherence.

  International journal of STD & AIDS 20021101

• Cutaneous EBV-related lymphoproliferative disorder in a 15-year-old boy with AIDS: an unusual clinical presentation.

  Journal of pediatric hematology/oncology 20021101

• Drug treatment for HIV-1-associated dementia.

  Current opinion in investigational drugs (London, England : 2000) 20021101

• Fat wasting--AZT vs. d4T.

  TreatmentUpdate 20021101

• One-pot synthesis of hydrogen phosphonate derivatives of d4T and AZT.

  Chemical communications (Cambridge, England) 20021021

• The prevalence and determinants of the K65R mutation in HIV-1 reverse transcriptase in tenofovir-naive patients.

  AIDS (London, England) 20021018

• Determination of the enantiomeric purity of nucleoside analogs related to d4T and acyclovir, new potential antiviral agents, using liquid chromatography on cellulose chiral stationary phases.

  Journal of chromatography. A 20021004

• cycloSal-d4TMP pronucleotides structural variations, mechanistic insights and antiviral activity.

  Current topics in medicinal chemistry 20021001

• Rheumatoid arthritis after 9 years of human immunodeficiency virus infection: possible contribution of tritherapy.

  The Journal of rheumatology 20021001

• Subtle decreases in stavudine phenotypic susceptibility predict poor virologic response to stavudine monotherapy in zidovudine-experienced patients.

  Journal of acquired immune deficiency syndromes (1999) 20021001

• HIV-associated lipodystrophy syndrome: LioN-HAART cohort: (lipodystrophy in patients on nucleoside-based HAART). Highly active antiretroviral therapy.

  Journal of acquired immune deficiency syndromes (1999) 20021001

• Type B lactic acidosis: a rare complication of antiretroviral therapy after cardiac surgery.

  The Annals of thoracic surgery 20021001

• Clinical lipoatrophy in HIV-1 patients on HAART is not associated with increased abdominal girth, hyperlipidaemia or glucose intolerance.

  HIV medicine 20021001

• The case against Zerit.

  GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies 20021001

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20021001

• Increased rates of lipolysis among human immunodeficiency virus-infected men receiving highly active antiretroviral therapy.

  Metabolism: clinical and experimental 20020901

• Modulation of human immunodeficiency virus (HIV)-specific immune response by using efavirenz, nelfinavir, and stavudine in a rescue therapy regimen for HIV-infected, drug-experienced patients.

  Clinical and diagnostic laboratory immunology 20020901

• Sustained high proportion of zidovudine-resistant HIV variants despite prolonged substitution of zidovudine by other nucleoside reverse transcriptase inhibitors.

  Journal of medical virology 20020901

• [Cytomegalovirus retinitis after highly active antiretroviral therapy: a case report].

  Archivos de la Sociedad Espanola de Oftalmologia 20020901

• Determination of lamivudine/stavudine/efavirenz in human serum using liquid chromatography/electrospray tandem mass spectrometry with ionization polarity switch.

  Biomedical chromatography : BMC 20020901

• Abnormalities of body fat distribution in HIV-infected persons treated with antiretroviral drugs: The Swiss HIV Cohort Study.

  Journal of acquired immune deficiency syndromes (1999) 20020901

• Development of drug resistance in HIV-1 patients receiving a combination of stavudine, lamivudine and efavirenz.

  International journal of antimicrobial agents 20020901

• Macrocytosis as an indicator of medication (zidovudine) adherence in patients with HIV infection.

  AIDS patient care and STDs 20020901

• Antiretroviral therapy regimens for neuro-AIDS.

  Current drug targets. Infectious disorders 20020901

• Impact of stavudine phenotype and thymidine analogues mutations on viral response to stavudine plus lamivudine in ALTIS 2 ANRS trial.

  Antiviral therapy 20020901

• Synthesis and anti-HIV activity of carbamates of antiviral agent stavudine.

  Antiviral chemistry & chemotherapy 20020901

• [Tenofovir in Study 903. Also effective and tolerable in first-line therapy].

  MMW Fortschritte der Medizin 20020822

• M184V is associated with a low incidence of thymidine analogue mutations and low phenotypic resistance to zidovudine and stavudine.

  AIDS (London, England) 20020816

• Antiretroviral treatment patterns and incident HIV-associated morphologic and lipid abnormalities in a population-based chort.

  Journal of acquired immune deficiency syndromes (1999) 20020801

• The pharmacokinetics of nelfinavir in HIV-1-infected children.

  Therapeutic drug monitoring 20020801

• HIV and refractory anemia with excess blasts (RAEB).

  American journal of hematology 20020801

• Effects of interleukin-2 plus highly active antiretroviral therapy on HIV-1 replication and proviral DNA (COSMIC trial).

  AIDS (London, England) 20020726

• New developments in anti-HIV chemotherapy.

  Biochimica et biophysica acta 20020718

• Mitochondrial DNA and nucleoside toxicity.

  The New England journal of medicine 20020718

• 3'-Azido-2',3'-dideoxythymidine induced deficiency of thymidine kinases 1, 2 and deoxycytidine kinase in H9 T-lymphoid cells.

  Biochemical pharmacology 20020715

• Abacavir substitution for nucleoside analogs in patients with HIV lipoatrophy: a randomized trial.

  JAMA 20020710

• ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase.

  Antimicrobial agents and chemotherapy 20020701

• Acute neuromyopathy syndrome.

  The Hopkins HIV report : a bimonthly newsletter for healthcare providers 20020701

• Immunophenotypic analyses of CD34(+) cell subsets in bone marrow from HIV-infected patients during highly- active antiretroviral therapy.

  European journal of clinical investigation 20020701

• A phase II randomized study of the virologic and immunologic effect of zidovudine + stavudine versus stavudine alone and zidovudine + lamivudine in patients with >300 CD4 cells who were antiretroviral naive (ACTG 298).

  AIDS research and human retroviruses 20020701

• Lopinavir-ritonavir versus nelfinavir for the initial treatment of HIV infection.

  The New England journal of medicine 20020627

• A 40-year-old woman who noticed a medication error, 1 year later.

  JAMA 20020626

• Sensitive and rapid liquid chromatography-tandem mass spectrometry method for the determination of stavudine in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020625

• Genotypic and phenotypic analyses of HIV-1 in antiretroviral-experienced patients treated with tenofovir DF.

  AIDS (London, England) 20020614

• Self-reported signs of lipodystrophy by persons living with HIV infection.

  International journal of STD & AIDS 20020601

• [Mononucleosis syndrome with viro-immunologic parameters similar to those of a primary HIV-1 infection after interruption of highly effective anti-retroviral treatment].

  Anales de medicina interna (Madrid, Spain : 1984) 20020601

• Selection of a T-cell line resistant to stavudine and zidovudine by prolonged treatment with stavudine.

  Antiviral therapy 20020601

• Significant differences between plasma HIV-1 RNA assays in HIV-1 subtype E infected patients treated with antiretroviral therapy.

  Asian Pacific journal of allergy and immunology 20020601

• Simple entry to 3'-substituted analogues of anti-HIV agent stavudine based on an anionic O --> C stannyl migration.

  The Journal of organic chemistry 20020531

• Addition of cyclophosphamide to antiretroviral therapy does not diminish the cellular reservoir in HIV-infected persons.

  AIDS research and human retroviruses 20020520

• HIV-1 subtype C reverse transcriptase sequences from drug-naive pregnant women in South Africa.

  AIDS research and human retroviruses 20020520

• Factors related to lipodystrophy and metabolic alterations in patients with human immunodeficiency virus infection receiving highly active antiretroviral therapy.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020515

• Prescribing practices in a population-based HIV postexposure prophylaxis program.

  AIDS (London, England) 20020503

• Paracardial lipodystrophy versus pericardial effusion in HIV positive patients.

  Heart (British Cardiac Society) 20020501

• Concurrent analysis of nucleoside reverse transcriptase inhibitors in a pool of endogenous nucleosides by short-end injection-capillary electrochromatography on a beta-cyclodextrin-bonded stationary phase.

  Electrophoresis 20020501

• LDL-receptors expression in HIV-infected patients: relations to antiretroviral therapy, hormonal status, and presence of lipodystrophy.

  European journal of clinical investigation 20020501

• FDA notifications. FDA changes information for stavudine label.

  AIDS alert 20020501

• Change in d4T label.

  AIDS patient care and STDs 20020501

• Adefovir nephrotoxicity and mitochondrial DNA depletion.

  Human pathology 20020501

• AIDS-related primary central nervous system lymphoma: prolonged remission associated with highly active antiretroviral therapy.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20020501

• Effects of aryl substituents on the anti-HIV activity of the arylphosphoramidate derivatives of stavudine.

  Antiviral chemistry & chemotherapy 20020501

• Thailand markets low-cost, 3-in-1 antiretroviral medication.

  AIDS policy & law 20020426

• Insights into the molecular mechanism of inhibition and drug resistance for HIV-1 RT with carbovir triphosphate.

  Biochemistry 20020423

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• HIV drug stavudine (Zerit, d4T) and symptoms mimicking Guillain-Barré syndrome.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20020416

• Selection of zidovudine resistance mutations and escape of human immunodeficiency virus type 1 from antiretroviral pressure in stavudine-treated pediatric patients.

  The Journal of infectious diseases 20020415

• Rhabdomyolysis with acute renal failure probably related to the interaction of atorvastatin and delavirdine.

  The American journal of medicine 20020415

• Immunologic reconstitution after 1 year of highly active antiretroviral therapy, with or without protease inhibitors.

  Journal of acquired immune deficiency syndromes (1999) 20020415

• Dose-escalating study of the safety and pharmacokinetics of nelfinavir in HIV-exposed neonates.

  Journal of acquired immune deficiency syndromes (1999) 20020415

• Safety and tolerability of combination antiretroviral post-exposure prophylaxis in a population-based setting.

  Journal of acquired immune deficiency syndromes (1999) 20020415

• [Treatment of HIV infection from the neurologic viewpoint. Therapy must reach the brain].

  MMW Fortschritte der Medizin 20020409

• Nucleoside-analogue reverse-transcriptase inhibitors plus nevirapine, nelfinavir, or ritonavir for pretreated children infected with human immunodeficiency virus type 1.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020401

• Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors.

  Antiviral research 20020401

• Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir.

  Antimicrobial agents and chemotherapy 20020401

• Higher rate of toxicity with no increased efficacy when hydroxyurea is added to a regimen of stavudine plus didanosine and nevirapine in primary HIV infection.

  Journal of acquired immune deficiency syndromes (1999) 20020401

• Severe interaction between ritonavir and acenocoumarol.

  The Annals of pharmacotherapy 20020401

• Broad nucleoside-analogue resistance implications for human immunodeficiency virus type 1 reverse-transcriptase mutations at codons 44 and 118.

  The Journal of infectious diseases 20020401

• Reported adherence as a determinant of response to highly active antiretroviral therapy in children who have human immunodeficiency virus infection.

  Pediatrics 20020401

• Gateways to Clinical Trials.

  Methods and findings in experimental and clinical pharmacology 20020401

• [Treatment of chronic hepatitis C in patients coinfected with HIV: tolerability, drug interactions, therapeutic indications].

  Gastroenterologie clinique et biologique 20020401

• Severe HIV-associated thrombocytopenia despite effective highly active antiretroviral therapy in a vertically infected child.

  AIDS (London, England) 20020329

• Carbocyclic dinucleoside polyphosphonates: interaction with HIV reverse transcriptase and antiviral activity.

  Journal of medicinal chemistry 20020314

• d4T and lactic acidosis with neuromuscular weakness: FDA warning.

  AIDS treatment news 20020308

• Prevalence of the mutational pattern E44D/A and/or V118I in the reverse transcriptase (RT) gene of HIV-1 in relation to treatment with nucleoside analogue RT inhibitors.

  Journal of medical virology 20020301

• Role of long-term nucleoside-analogue therapy in lipodystrophy and metabolic disorders in human immunodeficiency virus-infected patients.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020301

• Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors.

  Antimicrobial agents and chemotherapy 20020301

• Novel use of a guanosine prodrug approach to convert 2',3'-didehydro-2',3'-dideoxyguanosine into a viable antiviral agent.

  Antimicrobial agents and chemotherapy 20020301

• Efavirenz-induced skin eruption and successful desensitization.

  The Annals of pharmacotherapy 20020301

• Simple rapid method for quantification of antiretrovirals by liquid chromatography-tandem mass-spectrometry.

  Clinical biochemistry 20020301

• Mutations in HIV-1 reverse transcriptase during therapy with abacavir, lamivudine and zidovudine in HIV-1-infected adults with no prior antiretroviral therapy.

  Antiviral therapy 20020301

• Comparative study of bis(benzyl)phosphate triesters of 2',3'-dideoxy-2',3'-didehydrothymidine (d4T) and cyclosal-d4TMP--hydrolysis, mechanistic insights and anti-HIV activity.

  Antiviral chemistry & chemotherapy 20020301

• Aryl-substituted and benzo-annulated cyc/osal-derivatives of 2',3'-dideoxy-2',3'-didehydrothymidine monophosphate--correlation of structure, hydrolysis properties and anti-HIV activity.

  Antiviral chemistry & chemotherapy 20020301

• Granulocyte-macrophage colony-stimulating factor enhances viral load in human brain tissue: amelioration with stavudine.

  AIDS (London, England) 20020215

• Efavirenz-induced leukocytoclastic vasculitis.

  Archives of internal medicine 20020211

• An APE that proofreads.

  Nature 20020207

• An exonucleolytic activity of human apurinic/apyrimidinic endonuclease on 3' mispaired DNA.

  Nature 20020207

• Severe ototoxicity in a health care worker who received postexposure prophylaxis with stavudine, lamivudine, and nevirapine after occupational exposure to HIV.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020201

• Azidodeoxythymidine and didehydrodeoxythymidine as inhibitors and substrates of the human herpesvirus 8 thymidine kinase.

  The Journal of antimicrobial chemotherapy 20020201

• Resistance to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries.

  Journal of acquired immune deficiency syndromes (1999) 20020201

• Stavudine, nevirapine and ritonavir in stable antiretroviral therapy-experienced children with human immunodeficiency virus infection.

  The Pediatric infectious disease journal 20020201

• Acute onset lactic acidosis and pancreatitis in the third trimester of pregnancy in HIV-1 positive women taking antiretroviral medication.

  Sexually transmitted infections 20020201

• Immune reconstitution eosinophilia due to schistosomiasis.

  Sexually transmitted infections 20020201

• Myelomeningocele in a child with intrauterine exposure to efavirenz.

  AIDS (London, England) 20020125

• Evidence of immune reconstitution in antiretroviral drug-experienced patients with advanced HIV disease.

  AIDS research and human retroviruses 20020120

• Effects of antiretroviral drug combinations on the differentiation of adipocytes.

  AIDS (London, England) 20020104

• Primary infection with a lamivudine-resistant hepatitis B virus.

  AIDS (London, England) 20020104

• Human infection with Cryptosporidium felis: case report and literature review.

  Emerging infectious diseases 20020101

• Pilot study of the effects of intermittent interleukin-2 on human immunodeficiency virus (HIV)-specific immune responses in patients treated during recently acquired HIV infection.

  The Journal of infectious diseases 20020101

• Use of highly active antiretroviral therapy in a cohort of HIV-seropositive women.

  American journal of public health 20020101

• Dioxolane guanosine, the active form of the prodrug diaminopurine dioxolane, is a potent inhibitor of drug-resistant HIV-1 isolates from patients for whom standard nucleoside therapy fails.

  Journal of acquired immune deficiency syndromes (1999) 20020101

• Body habitus changes and metabolic alterations in protease inhibitor-naive HIV-1-infected patients treated with two nucleoside reverse transcriptase inhibitors.

  Journal of acquired immune deficiency syndromes (1999) 20020101

• Antiretroviral rounds. A very discordant response.

  AIDS clinical care 20020101

• Efficacy and safety of stavudine plus didanosine in asymptomatic HIV-infected children with plasma HIV RNA below 50,000 copies per milliliter.

  HIV clinical trials 20020101

• Determination of some anti-human immunodeficiency virus nucleosides by capillary zone electrophoresis-tandem mass spectrometry.

  Electrophoresis 20020101

• Viral and immunologic follow up of 4 to 9 years of AIDS treatments by quadruple combinations of virostatics including integrase inhibitors applied in short sequences differing by drug rotation.

  Acta pharmacologica Sinica 20020101

• Improved method for the simultaneous determination of d4T, 3TC and ddl intracellular phosphorylated anabolites in human peripheral-blood mononuclear cells using high-performance liquid chromatography/tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20020101

• Stavudine-associated peripheral neuropathy in zidovudine-naïve patients: effect of stavudine exposure and antiretroviral experience.

  Advances in therapy 20020101

• Randomized, open-label, comparative trial to evaluate the efficacy and safety of three antiretroviral drug combinations including two nucleoside analogues and nevirapine for previously untreated HIV-1 Infection: the OzCombo 2 study.

  HIV clinical trials 20020101

• SENC (Spanish efavirenz vs. nevirapine comparison) trial: a randomized, open-label study in HIV-infected naive individuals.

  HIV clinical trials 20020101

• Long-term efficacy and safety of ritonavir/indinavir at 400/400 mg twice a day in combination with two nucleoside reverse transcriptase inhibitors as first line antiretroviral therapy.

  HIV medicine 20020101

• Risk factors for the HIV-associated lipodystrophy syndrome in a closed cohort of patients after 3 years of antiretroviral treatment.

  HIV medicine 20020101

• Human immunodeficiency virus genotype and hypertriglyceridemia.

  Journal of clinical laboratory analysis 20020101

• Clinical implications of CNS penetration of antiretroviral drugs.

  CNS drugs 20020101

• The HYDILE trial: efficacy and tolerance of a quadruple combination of reverse transcriptase inhibitors versus the same regimen plus hydroxyurea or hydroxyurea and interleukin-2 in HIV-infected patients failing protease inhibitor-based combinations.

  HIV clinical trials 20020101

• Immune reconstitution during intensive chemotherapy in patients with human immunodeficiency virus related non-Hodgkin lymphoma.

  The hematology journal : the official journal of the European Haematology Association 20020101

• FTC superiority over d4T in phase III trial.

  Positively aware : the monthly journal of the Test Positive Aware Network 20020101

• Antiretroviral pharmacokinetics in the paediatric population: a review.

  Clinical pharmacokinetics 20020101

• Lamivudine 300 mg QD versus continued lamivudine 150 mg BID with stavudine and a protease inhibitor in suppressed patients.

  HIV clinical trials 20020101

• Hepatic adverse events during highly active antiretroviral therapy containing nevirapine: a case report.

  Annals of clinical microbiology and antimicrobials 20020101

• Stavudine once daily.

  Drugs 20020101

• [Drug-induced acute pancreatitis: a personal contribution].

  Chirurgia italiana 20020101

• Synthesis and anti-HIV activity of [d4U]-[trovirdine analogue] and [d4T]-[trovirdine analogue] heterodimers as inhibitors of HIV-1 reverse transcriptase.

  Nucleosides, nucleotides & nucleic acids 20020101

• [Acute severe pancreatitis caused by anti-HIV drugs].

  Annali italiani di chirurgia 20020101

• Symptomatic elevations of lactic acid and their response to treatment manipulation in human immunodeficiency virus-infected persons: a case series.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20011215

• Nevirapine-containing antiretroviral therapy in HIV-1 infected patients results in an anti-atherogenic lipid profile.

  AIDS (London, England) 20011207

• Symptomatic lactic acidosis in hospitalized antiretroviral-treated patients with human immunodeficiency virus infection: a report of 12 cases.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20011201

• Hyperlactatemia and antiretroviral therapy: the Swiss HIV Cohort Study.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20011201

• Failure of stavudine-lamivudine combination therapy in antiretroviral-naive patients with AZT-like HIV-1 resistance mutations.

  Journal of medical virology 20011201

• Emerging role of riboflavin in the treatment of nucleoside analogue-induced type B lactic acidosis.

  AIDS patient care and STDs 20011201

• Regression of HIV-associated pulmonary arterial hypertension and long-term survival during antiretroviral therapy.

  Swiss medical weekly 20011201

• Possible mechanism of toxicity of zidovudine by induction of apoptosis of CD4+ and CD8+ T-cells in vivo.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20011201

• Skin eruption 8 days after a single dose of efavirenz-containing combination therapy.

  Japanese journal of infectious diseases 20011201

• HIV-1 reverse transcriptase mutations found in a drug-experienced patient confer reduced susceptibility to multiple nucleoside reverse transcriptase inhibitors.

  Antiviral therapy 20011201

• [Therapeutic aspects of HIV/AIDS infected patients and evaluation of therapeutic protocols].

  Acta pharmaceutica Hungarica 20011201

• Drugs for HIV infection.

  The Medical letter on drugs and therapeutics 20011126

• Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons.

  Proceedings of the National Academy of Sciences of the United States of America 20011120

• Inhibition of purified recombinant reverse transcriptase from wild-type and zidovudine-resistant clinical isolates of human immunodeficiency virus type 1 by zidovudine, stavudine, and lamivudine triphosphates.

  The Journal of infectious diseases 20011115

• Anti-human immunodeficiency virus drugs are ineffective against Pneumocystis carinii in vitro and in vivo.

  The Journal of infectious diseases 20011115

• New developments in anti-HIV chemotherapy.

  Current medicinal chemistry 20011101

• Resistance profile and cross-resistance of HIV-1 among patients failing a non-nucleoside reverse transcriptase inhibitor-containing regimen.

  Journal of medical virology 20011101

• Treatment of hepatitis C virus and HIV co-infections.

  Clinics in liver disease 20011101

• Decrease of elevated N,N-dimethylglycine and N-methylglycine in human immunodeficiency virus infection during short-term highly active antiretroviral therapy.

  Metabolism: clinical and experimental 20011101

• [Acute myocardial infarct in HIV-positive patients in treatment with protease inhibitors].

  Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20011101

• Prevalence of adverse events associated with potent antiretroviral treatment: Swiss HIV Cohort Study.

  Lancet (London, England) 20011020

• Long-term quality of life outcomes in three antiretroviral treatment strategies for HIV-1 infection.

  AIDS (London, England) 20011019

• Effect of therapeutic immunization with HIV type 1 recombinant glycoprotein 160 ImmunoAG vaccine in HIV-infected individuals with CD4+ T cell counts of >or=500 and 200-400/mm3 (AIDS Clinical Trials Group Study 246/946).

  AIDS research and human retroviruses 20011010

• Low frequency of severe hepatotoxicity and association with HCV coinfection in HIV-positive patients treated with HAART.

  Journal of acquired immune deficiency syndromes (1999) 20011001

• Phenotypic and genotypic resistance to nucleoside reverse transcriptase inhibitors in HIV-1 clinical isolates.

  HIV medicine 20011001

• Comparison of genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 isolates from patients treated with stavudine and didanosine or zidovudine and lamivudine.

  The Journal of infectious diseases 20010915

• Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5.

  The Journal of biological chemistry 20010914

• Mismatched double-stranded RNA (polyI-polyC(12)U) is synergistic with multiple anti-HIV drugs and is active against drug-sensitive and drug-resistant HIV-1 in vitro.

  Antiviral research 20010901

• Highly active antiretroviral therapy in human immunodeficiency virus type 1-infected children: analysis of cellular immune responses.

  Clinical and diagnostic laboratory immunology 20010901

• Liver failure after long-term nucleoside antiretroviral therapy.

  Lancet (London, England) 20010901

• Novel deletion of HIV type 1 reverse transcriptase residue 69 conferring selective high-level resistance to nevirapine.

  AIDS research and human retroviruses 20010901

• Failure of a short-term prednisone regimen to prevent nevirapine-associated rash: a double-blind placebo-controlled trial: the GESIDA 09/99 study.

  Journal of acquired immune deficiency syndromes (1999) 20010901

• Synthesis of 5-alkenylated D4T analogues via the Pd-catalyzed cross-coupling reaction.

  Nucleosides, nucleotides & nucleic acids 20010901

• Low-rate emergence of thymidine analogue mutations and multi-drug resistance mutations in the HIV-1 reverse transcriptase gene in therapy-naive patients receiving stavudine plus lamivudine combination therapy.

  Antiviral therapy 20010901

• Simultaneous quantitation of nucleoside HIV-1 reverse transcriptase inhibitors by short-end injection capillary electrochromatography on a beta-cyclodextrin-bonded silica stationary phase.

  Journal of chromatography. A 20010824

• Susceptibility of human T cell leukemia virus type 1 to reverse-transcriptase inhibitors: evidence for resistance to lamivudine.

  The Journal of infectious diseases 20010815

• Adefovir and tenofovir susceptibilities of HIV-1 after 24 to 48 weeks of adefovir dipivoxil therapy: genotypic and phenotypic analyses of study GS-96-408.

  Journal of acquired immune deficiency syndromes (1999) 20010815

• Thymidine analog and multinucleoside resistance mutations are associated with decreased phenotypic susceptibility to stavudine in HIV type 1 isolated from zidovudine-naive patients experiencing viremia on stavudine-containing regimens.

  AIDS research and human retroviruses 20010810

• Antiviral drugs: current state of the art.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20010801

• Value of patient self-report and plasma human immunodeficiency virus protease inhibitor level as markers of adherence to antiretroviral therapy: relationship to virologic response.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010801

• Genotypic correlates of a virologic response to stavudine after zidovudine monotherapy.

  Journal of acquired immune deficiency syndromes (1999) 20010801

• Disseminated histoplasmosis presenting as pyoderma gangrenosum-like lesions in a patient with acquired immunodeficiency syndrome.

  International journal of dermatology 20010801

• Pharmacokinetics of nelfinavir in human immunodeficiency virus-infected infants.

  The Pediatric infectious disease journal 20010801

• Strategies for treating HIV-related lipodystrophy.

  Expert opinion on investigational drugs 20010801

• Effects of treatment intensification with hydroxyurea in HIV-infected patients with virologic suppression.

  AIDS (London, England) 20010727

• Clinical assessment of HIV-associated lipodystrophy in an ambulatory population.

  AIDS (London, England) 20010727

• Gynaecomastia in a male patient during stavudine and didanosine treatment for HIV infection.

  International journal of STD & AIDS 20010701

• In vivo pharmacokinetics and metabolism of anti-human immunodeficiency virus agent D4T-5'-[p-bromophenyl methoxyalaninyl phosphate] (SAMPIDINE) in mice.

  Drug metabolism and disposition: the biological fate of chemicals 20010701

• Stavudine versus zidovudine and the development of lipodystrophy.

  Journal of acquired immune deficiency syndromes (1999) 20010701

• Predictors of protease inhibitor-associated adverse events.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20010701

• Adefovir nephrotoxicity: possible role of mitochondrial DNA depletion.

  Human pathology 20010701

• [Immunologic response to antiretroviral treatment with combined stavudine, didanosine and nevirapine].

  Presse medicale (Paris, France : 1983) 20010701

• Clinical manifestations and management of pediatric HIV infection.

  Indian journal of pediatrics 20010701

• The prevalence of lipodystrophy in an ambulant HIV-infected population: it all depends on the definition.

  HIV medicine 20010701

• Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma.

  The Journal of biological chemistry 20010629

• Updated U.S. Public Health Service Guidelines for the Management of Occupational Exposures to HBV, HCV, and HIV and Recommendations for Postexposure Prophylaxis.

  MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports 20010629

• Analysis of human immunodeficiency virus type 1 drug resistance in children receiving nucleoside analogue reverse-transcriptase inhibitors plus nevirapine, nelfinavir, or ritonavir (Pediatric AIDS Clinical Trials Group 377).

  The Journal of infectious diseases 20010615

• Selection by AZT and rapid replacement in the absence of drugs of HIV type 1 resistant to multiple nucleoside analogs.

  AIDS research and human retroviruses 20010610

• Severe lactic acidosis and thiamine administration in an HIV-infected patient on HAART.

  International journal of STD & AIDS 20010601

• Adherence over 48 weeks in an antiretroviral clinical trial: variable within patients, affected by toxicities and independently predictive of virological response.

  Antiviral therapy 20010601

• Nucleoside analogue-induced fatal lactic acidosis in two HIV-infected patients in Singapore.

  Singapore medical journal 20010601

• Persistence of zidovudine-resistance mutations in HIV-1 isolates from patients removed from zidovudine therapy for at least 3 years and switched to a stavudine-containing regimen.

  AIDS (London, England) 20010525

• Lactic acid levels in children perinatally treated with antiretroviral agents to prevent HIV transmission.

  AIDS (London, England) 20010525

• Fatal portal hypertension, liver failure, and mitochondrial dysfunction after HIV-1 nucleoside analogue-induced hepatitis and lactic acidaemia.

  Lancet (London, England) 20010505

• HIV in body fluids during primary HIV infection: implications for pathogenesis, treatment and public health.

  AIDS (London, England) 20010504

• Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection.

  AIDS (London, England) 20010504

• Effect of stavudine on mitochondrial genome and fatty acid oxidation in lean and obese mice.

  The Journal of pharmacology and experimental therapeutics 20010501

• An integrated system to study multiply substituted human immunodeficiency virus type 1 reverse transcriptase.

  Analytical biochemistry 20010501

• Choosing which nuke to use first.

  The AIDS reader 20010501

• Lipodystrophy in HIV-infected children is associated with high viral load and low CD4+ -lymphocyte count and CD4+ -lymphocyte percentage at baseline and use of protease inhibitors and stavudine.

  Journal of acquired immune deficiency syndromes (1999) 20010501

• [HIV-HBV coinfection and the liver].

  Gastroenterologie clinique et biologique 20010501

• Resistant to everything.

  AIDS clinical care 20010501

• Three-drug combinations of emivirine and nucleoside reverse transcriptase inhibitors in vitro: long-term culture of HIV-1-infected cells and breakthrough viruses.

  Antiviral chemistry & chemotherapy 20010501

• The valine-to-threonine 75 substitution in human immunodeficiency virus type 1 reverse transcriptase and its relation with stavudine resistance.

  The Journal of biological chemistry 20010427

• Chemotherapy for human immunodeficiency virus-associated non-Hodgkin's lymphoma in combination with highly active antiretroviral therapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010415

• R211K and L214F do not invariably confer high level phenotypic resistance to thymidine analogs in zidovudine-naive patients with M184V.

  Journal of acquired immune deficiency syndromes (1999) 20010415

• Determination of serum levels of thirteen human immunodeficiency virus-suppressing drugs by high-performance liquid chromatography.

  Journal of chromatography. A 20010413

• Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy.

  AIDS (London, England) 20010413

• Differing reverse transcriptase mutation patterns in individuals experiencing viral rebound on first-line regimens with stavudine/didanosine and stavudine/lamivudine.

  AIDS (London, England) 20010413

• Long-term safety and efficacy of nevirapine, stavudine and lamivudine in a real-world setting.

  AIDS (London, England) 20010413

• Amino acid deletion at codon 67 and Thr-to-Gly change at codon 69 of human immunodeficiency virus type 1 reverse transcriptase confer novel drug resistance profiles.

  Journal of virology 20010401

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  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010401

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  American journal of ophthalmology 20010301

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  AIDS care 20010201

• Making the most of sparse clinical data by using a predictive-model-based analysis, illustrated with a stavudine pharmacokinetic study.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010201

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  Antiviral research 20010201

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  AIDS (London, England) 20010126

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  AIDS research and human retroviruses 20010120

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  AIDS treatment news 20010112

• Changes in host cell molecules acquired by circulating HIV-1 in patients treated with highly active antiretroviral therapy and interleukin-2.

  AIDS (London, England) 20010105

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  AIDS (London, England) 20010105

• Pathological fractures in AIDS patients with osteopenia and osteoporosis induced by antiretroviral therapy.

  AIDS (London, England) 20010105

• Renal tubular acidosis and hypophosphataemia after treatment with nucleoside reverse transcriptase inhibitors.

  AIDS (London, England) 20010105

• ABT-378/ritonavir plus stavudine and lamivudine for the treatment of antiretroviral-naive adults with HIV-1 infection: 48-week results.

  AIDS (London, England) 20010105

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  Journal of acquired immune deficiency syndromes (1999) 20010101

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  Pharmacotherapy 20010101

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  Scandinavian journal of infectious diseases 20010101

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  Farmaco (Societa chimica italiana : 1989) 20010101

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  FDA consumer 20010101

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  Drug safety 20010101

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  The Annals of pharmacotherapy 20010101

• Eruptive cheilitis: a new adverse effect in reactive HIV-positive patients subjected to high activity antiretroviral therapy (HAART). Presentation of six clinical cases.

  Medicina oral : organo oficial de la Sociedad Espanola de Medicina Oral y de la Academia Iberoamericana de Patologia y Medicina Bucal 20010101

• Direct determination of phosphorylated intracellular anabolites of stavudine (d4T) by liquid chromatography/tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20010101

• Clinical and laboratory signs of mitochondrial dysfunction secondary to nucleoside analogue antiretroviral therapy are reversible.

  Scandinavian journal of infectious diseases 20010101

• Determination of pharmacokinetic parameters of stavudine in Japanese patients infected with HIV-1, using a Gaussian-like input rate function.

  European journal of drug metabolism and pharmacokinetics 20010101

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  Nucleosides, nucleotides & nucleic acids 20010101

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  Nucleosides, nucleotides & nucleic acids 20010101

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  Nucleosides, nucleotides & nucleic acids 20010101

• Tenofovir (PMPA) is less susceptible to pyrophosphorolysis and nucleotide-dependent chain-terminator removal than zidovudine or stavudine.

  Nucleosides, nucleotides & nucleic acids 20010101

• Anti-HIV activity of novel phosphonate derivatives of AZT, d4T, and ddA.

  Nucleosides, nucleotides & nucleic acids 20010101

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  Nucleosides, nucleotides & nucleic acids 20010101

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  Nucleosides, nucleotides & nucleic acids 20010101

• Differential human immunodeficiency virus-suppressive activity of reverse transcription inhibitors in resting and activated peripheral blood lymphocytes: implications for therapy.

  Journal of human virology 20010101

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  HIV clinical trials 20010101

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  HIV clinical trials 20010101

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  Antiviral chemistry & chemotherapy 20010101

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  Antiviral chemistry & chemotherapy 20010101

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  Antiviral therapy 20010101

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  Antiviral therapy 20010101

• Disseminated manifestation of Kaposi's Sarcoma in newly diagnosed AIDS in an african female.

  Medical science monitor : international medical journal of experimental and clinical research 20010101

• Thymidine-analog and multi-nucleoside resistance mutations are observed in both zidovudine-naive and zidovudine-experienced subjects with viremia after treatment with stavudine-containing regimens.

  Journal of human virology 20010101

• MIKADO: a multicentre, open-label pilot study to evaluate the antiretroviral activity and safety of saquinavir with stavudine and zalcitabine.

  HIV medicine 20010101

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  HIV medicine 20010101

• Continuing HIV therapy in the ICU.

  Critical care (London, England) 20010101

• Baseline antiretroviral drug susceptibility influences treatment response in patients receiving saquinavir-enhancing therapy.

  HIV clinical trials 20010101

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  HIV clinical trials 20010101

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  HIV clinician 20010101

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  GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies 20010101

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  Przeglad epidemiologiczny 20010101

• Chronic stavudine exposure induces hepatic mitochondrial toxicity in adult Erythrocebus patas monkeys.

  Journal of human virology 20010101

• Side effects. FDA issues warning about d4T and ddI during pregnancy.

  TreatmentUpdate 20010101

• Increasing cerebrospinal fluid chemokine concentrations despite undetectable cerebrospinal fluid HIV RNA in HIV-1-infected patients receiving antiretroviral therapy.

  Journal of acquired immune deficiency syndromes (1999) 20001215

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  Biological & pharmaceutical bulletin 20001201

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  Antiviral chemistry & chemotherapy 20001101

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  AIDS (London, England) 20000929

• A QSAR study investigating the effect of L-alanine ester variation on the anti-HIV activity of some phosphoramidate derivatives of d4T.

  Bioorganic & medicinal chemistry letters 20000918

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  Bioorganic & medicinal chemistry letters 20000918

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  Nucleosides, nucleotides & nucleic acids 20000901

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  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20000901

• Prevalence and characteristics of multinucleoside-resistant human immunodeficiency virus type 1 among European patients receiving combinations of nucleoside analogues.

  Antimicrobial agents and chemotherapy 20000801

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  Annals of internal medicine 20000801

• Didanosine-induced hepatitis.

  The American journal of gastroenterology 20000801

• Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase.

  The EMBO journal 20000717

• In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-beta-D-dioxolane-guanosine and suppress resistance to 3'-azido-3'-deoxythymidine.

  Antimicrobial agents and chemotherapy 20000701

• Drug resistance and drug combination features of the human immunodeficiency virus inhibitor, BCH-10652 [(+/-)-2'-deoxy-3'-oxa-4'-thiocytidine, dOTC].

  Antiviral chemistry & chemotherapy 20000701

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  AIDS (London, England) 20000616

• Selection and characterization of human immunodeficiency virus type 1 variants resistant to the (+) and (-) enantiomers of 2'-deoxy-3'-oxa-4'-thio-5-fluorocytidine.

  Antimicrobial agents and chemotherapy 20000501

• Increased incidence of peripheral neuropathy with co-administration of stavudine and isoniazid in HIV-infected individuals.

  AIDS (London, England) 20000331

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  Antiviral chemistry & chemotherapy 20000301

• Incidence of neuropathy in HIV-infected patients on monotherapy versus those on combination therapy with didanosine, stavudine and hydroxyurea.

  AIDS (London, England) 20000218

• Excess peripheral neuropathy in patients treated with hydroxyurea plus didanosine and stavudine for HIV infection.

  AIDS (London, England) 20000218

• A randomized, comparative study of lamivudine plus stavudine, with indinavir or nelfinavir, in treatment-experienced HIV-infected patients.

  AIDS (London, England) 20000128

• Activities of masked 2',3'-dideoxynucleoside monophosphate derivatives against human immunodeficiency virus in resting macrophages.

  Antimicrobial agents and chemotherapy 20000101

• Decreased methadone effect after ritonavir initiation.

  Pharmacotherapy 20000101

• Synthesis and antiviral activity of C-5 substituted analogues of d4T bearing methylamino- or methyldiamino-linker arms.

  Nucleosides, nucleotides & nucleic acids 20000101

• Potential multifunctional inhibitors of HIV-1 reverse transcriptase. Novel [AZT]-[TSAO-T] and [d4T]-[TSAO-T] heterodimers modified in the linker and in the dideoxynucleoside region.

  Journal of medicinal chemistry 19991216

• Design and synthesis of lipophilic phosphoramidate d4T-MP prodrugs expressing high potency against HIV in cell culture: structural determinants for in vitro activity and QSAR.

  Journal of medicinal chemistry 19991007

• Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.

  Molecular pharmacology 19991001

• A novel genotype encoding a single amino acid insertion and five other substitutions between residues 64 and 74 of the HIV-1 reverse transcriptase confers high-level cross-resistance to nucleoside reverse transcriptase inhibitors. Abacavir CNA2007 International Study Group.

  Journal of acquired immune deficiency syndromes (1999) 19991001

• Safety and antiretroviral effects of combined didanosine and stavudine therapy in HIV-infected individuals with CD4 counts of 200 to 500 cells/mm3.

  Journal of acquired immune deficiency syndromes (1999) 19990901

• Once-daily administration of didanosine in combination with stavudine in antiretroviral-naive patients. The STADI Group.

  Journal of acquired immune deficiency syndromes (1999) 19990901

• Stavudine-induced macrocytosis during therapy for human immunodeficiency virus infection.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 19990801

• Synthesis and anti-HIV activity of some novel arylphosphate and H-phosphonate derivatives of 3'-azido-2',3'-dideoxythymidine and 2',3'-didehydro-2',3'-dideoxythymidine.

  Antiviral research 19990701

• [Conjugates of 2',3'-didehydro-3'-deoxythymidine with thymogen. Synthesis and anti-HIV activity].

  Bioorganicheskaia khimiia 19990701

• cycloSal-Pronucleotides of 2',3'-dideoxyadenosine and 2', 3'-dideoxy-2',3'-didehydroadenosine: synthesis and antiviral evaluation of a highly efficient nucleotide delivery system.

  Journal of medicinal chemistry 19990506

• cycloSal-Pronucleotides of 2'-fluoro-ara- and 2'-fluoro-ribo-2',3'- dideoxyadenosine as a strategy to bypass a metabolic blockade.

  Journal of medicinal chemistry 19990506

• Suppression of replication of multidrug-resistant HIV type 1 variants by combinations of thymidylate synthase inhibitors with zidovudine or stavudine.

  Molecular pharmacology 19990301

• The presence of substituents on the aryl moiety of the aryl phosphoramidate derivative of d4T enhances anti-HIV efficacy in cell culture: A structure-activity relationship.

  Journal of medicinal chemistry 19990211

• Human immunodeficiency virus type 1 expressing the lamivudine-associated M184V mutation in reverse transcriptase shows increased susceptibility to adefovir and decreased replication capability in vitro.

  The Journal of infectious diseases 19990101

• Hypertensive crisis secondary to phenylpropanolamine interacting with triple-drug therapy for HIV prophylaxis.

  The American journal of medicine 19990101

• Synthesis of a nucleoside bioconjugate system as a potential anti-HIV agent.

  Nucleosides & nucleotides 19990101

• Synthesis of novel C-5 substituted d4T analogues bearing linker arms as potential anti-HIV agents.

  Nucleosides & nucleotides 19990101

• New series of mixed pronucleotides. Synthesis and anti-HIV activities of mononucleoside phenyl SATE phosphotriesters.

  Nucleosides & nucleotides 19990101

• [Clinical case of the month. Apropos of pancytopenia in a seropositive patient].

  Revue medicale de Liege 19981201

• Enhancing effects of a mono-bromo substitution at the para position of the phenyl moiety on the metabolism and anti-HIV activity of d4T-phenyl methoxyalaninyl phosphate derivatives.

  Bioorganic & medicinal chemistry letters 19981117

• Lactate cannot substitute for alanine in d4T-based anti-HIV nucleotide prodrugs--despite efficient esterase-mediated hydrolysis.

  Bioorganic & medicinal chemistry letters 19981103

• Synthesis, anti-human immunodeficiency virus activity and esterase lability of some novel carboxylic ester-modified phosphoramidate derivatives of stavudine (d4T).

  Antiviral chemistry & chemotherapy 19981101

• Multiple dideoxynucleoside analogue-resistant (MddNR) HIV-1 strains isolated from patients from different European countries.

  AIDS (London, England) 19981022

• Aryl phosphate derivatives of 3'-deoxythymidine are not potent anti-human immunodeficiency virus agents.

  Antiviral chemistry & chemotherapy 19980901

• D4T-5'-[p-bromophenyl methoxyalaninyl phosphate] as a potent and non-toxic anti-human immunodeficiency virus agent.

  Antiviral chemistry & chemotherapy 19980901

• Metabolism of 2',3'-dideoxy-2',3'-didehydro-beta-L(-)-5-fluorocytidine and its activity in combination with clinically approved anti-human immunodeficiency virus beta-D(+) nucleoside analogs in vitro.

  Antimicrobial agents and chemotherapy 19980701

• 3'-Azido-3'-deoxythymidine (AZT) mediates cross-resistance to nucleoside analogs in the case of AZT-resistant human immunodeficiency virus type 1 variants.

  Journal of virology 19980601

• Tri-N-Boc-tetraazamacrocycle-nucleoside conjugates: synthesis and anti-HIV activities.

  Nucleosides & nucleotides 19980501

• Imidazo[1,5-b]pyridazine-d4T conjugates: synthesis and anti-human immunodeficiency virus evaluation.

  Antiviral chemistry & chemotherapy 19980501

• cycloSal-2',3'-dideoxy-2',3'-didehydrothymidine monophosphate (cycloSal-d4TMP): synthesis and antiviral evaluation of a new d4TMP delivery system.

  Journal of medicinal chemistry 19980423

• Synergistic inhibition of HIV-1 by an antisense oligonucleotide and nucleoside analog reverse transcriptase inhibitors.

  Antiviral research 19980401

• Indinavir-induced renal failure.

  AIDS (London, England) 19980305

• Synthesis and anti-HIV activity of some novel chain-extended phosphoramidate derivatives of d4T (stavudine): esterase hydrolysis as a rapid predictive test for antiviral potency.

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  Nederlands tijdschrift voor geneeskunde 19980221

• TXU (anti-CD7)-pokeweed antiviral protein as a potent inhibitor of human immunodeficiency virus.

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• Metabolism and anti-HIV activity of phosphoramidate derivatives of D4T-MP with variations in the amino acid moiety.

  Advances in experimental medicine and biology 19980101

• Mutations in the human immunodeficiency virus type 1 reverse transcriptase gene observed in stavudine and didanosine strains obtained by in vitro passages.

  Research in virology 19980101

• Anti-HIV antiviral activity of stavudine in a thymidine kinase-deficient cellular line.

  Antiviral therapy 19980101

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• Lamivudine-stavudine-induced liver failure in hepatitis B cirrhosis.

  The American journal of gastroenterology 19970901

• Phosphoramidate derivatives of d4T as inhibitors of HIV: the effect of amino acid variation.

  Antiviral research 19970801

• Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus.

  Antimicrobial agents and chemotherapy 19970701

• Inhibition of replication of HIV in primary monocyte/macrophages by different antiviral drugs and comparative efficacy in lymphocytes.

  Journal of leukocyte biology 19970701

• Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89.

  Antimicrobial agents and chemotherapy 19970501

• Clinical efficacy of monotherapy with stavudine compared with zidovudine in HIV-infected, zidovudine-experienced patients. A randomized, double-blind, controlled trial. Bristol-Myers Squibb Stavudine/019 Study Group.

  Annals of internal medicine 19970301

• Acetyl-carnitine deficiency in AIDS patients with neurotoxicity on treatment with antiretroviral nucleoside analogues.

  AIDS (London, England) 19970201

• Stavudine selectively induces apoptosis in HIV type 1-infected cells.

  AIDS research and human retroviruses 19970120

• Antiretrovirus specificity and intracellular metabolism of 2',3' -didehydro-2',3'-dideoxythymidine (stavudine) and its 5'-monophosphate triester prodrug So324.

  Molecular pharmacology 19961101

• Novel mutation (K70E) in human immunodeficiency virus type 1 reverse transcriptase confers decreased susceptibility to 9-[2-(phosphonomethoxy)ethyl]adenine in vitro.

  Antimicrobial agents and chemotherapy 19960901

• Anti-HIV and anti-HBV activity and resistance profile of 2',3'-dideoxy-3'-thiacytidine (3TC) and its arylphosphoramidate derivative CF 1109.

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• Mechanism of anti-HIV action of masked alaninyl d4T-MP derivatives.

  Proceedings of the National Academy of Sciences of the United States of America 19960709

• 2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis.

  Molecular pharmacology 19960701

• Evaluation of reverse transcriptase and protease inhibitors in two-drug combinations against human immunodeficiency virus replication.

  Antimicrobial agents and chemotherapy 19960601

• Potentiation of the stavudine anti-human immunodeficiency virus activity by 5-fluorouracil.

  Antimicrobial agents and chemotherapy 19960501

• Aryl phosphoramidate derivatives of d4T have improved anti-HIV efficacy in tissue culture and may act by the generation of a novel intracellular metabolite.

  Journal of medicinal chemistry 19960412

• Favorable interaction of beta-L(-) nucleoside analogues with clinically approved anti-HIV nucleoside analogues for the treatment of human immunodeficiency virus.

  Biochemical pharmacology 19960322

• Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy.

  Journal of virology 19960201

• Selective pressure of a quinoxaline nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-1 replication results in the emergence of nucleoside RT-inhibitor-specific (RT Leu-74-->Val or Ile and Val-75-->Leu or Ile) HIV-1 mutants.

  Proceedings of the National Academy of Sciences of the United States of America 19960109

• Comparative analysis of anti-human immunodeficiency virus type 1 activities of dideoxynucleoside analogs in resting and activated peripheral blood mononuclear cells.

  Antimicrobial agents and chemotherapy 19951101

• Novel mutations in reverse transcriptase of human immunodeficiency virus type 1 reduce susceptibility to foscarnet in laboratory and clinical isolates.

  Antimicrobial agents and chemotherapy 19950501

• Biologic effects and safety of stavudine: overview of phase I and II clinical trials.

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• Stavudine in patients with AIDS and AIDS-related complex: AIDS clinical trials group 089.

  The Journal of infectious diseases 19950301

• Dose-related activity of stavudine in patients infected with human immunodeficiency virus.

  The Journal of infectious diseases 19950301

• Genotypic and phenotypic analysis of human immunodeficiency virus type 1 isolates from patients on prolonged stavudine therapy.

  The Journal of infectious diseases 19941101

• Novel mutation (V75T) in human immunodeficiency virus type 1 reverse transcriptase confers resistance to 2',3'-didehydro-2',3'-dideoxythymidine in cell culture.

  Antimicrobial agents and chemotherapy 19940601

• Identification of novel mutations that confer drug resistance in the human immunodeficiency virus polymerase gene.

  Leukemia 19940401

• Prodrugs of 2',3'-didehydro-3'-deoxythymidine (D4T): synthesis, antiviral activity, and rapid pharmacokinetic evaluation.

  Journal of pharmaceutical sciences 19940301

• Synthesis and anti-HIV evaluation of D4T and D4T 5'-monophosphate prodrugs.

  Journal of medicinal chemistry 19930402

• A single conservative amino acid substitution in the reverse transcriptase of human immunodeficiency virus-1 confers resistance to (+)-(5S)-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)imidazo[4,5, 1- jk][1,4]benzodiazepin-2(1H)-thione (TIBO R82150).

  Molecular pharmacology 19930101

• Evaluation of the combination effect of different antiviral compounds against HIV in vitro.

  Scandinavian journal of infectious diseases 19930101

• Suppression of murine retroviral disease by 2',3'-didehydro-2',3'-dideoxythymidine (D4T).

  Antiviral research 19921001

• Synthesis of pyranoid analogues of the anti-HIV active 3'-deoxy-2',3'-didehydrothymidine (D4T).

  Archiv der Pharmazie 19920801

• In vitro selection and molecular characterization of human immunodeficiency virus-1 resistant to non-nucleoside inhibitors of reverse transcriptase.

  Molecular pharmacology 19920301

• Substrate specificity of human deoxycytidine kinase toward antiviral 2',3'-dideoxynucleoside analogs.

  Biochemical pharmacology 19920122

• New synthesis of 2',3'-didehydro-2',3'-dideoxynucleosides.

  Acta chemica Scandinavica (Copenhagen, Denmark : 1989) 19911101

• Highly potent and selective inhibition of human immunodeficiency virus type 1 by a novel series of 6-substituted acyclouridine derivatives.

  Molecular pharmacology 19910601

• Biological comparison of wild-type and zidovudine-resistant isolates of human immunodeficiency virus type 1 from the same subjects: susceptibility and resistance to other drugs.

  Antimicrobial agents and chemotherapy 19910501

• Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.

  Molecular pharmacology 19910501

• Inhibitory effects of selected antiviral compounds on human hepatitis B virus DNA synthesis.

  Antimicrobial agents and chemotherapy 19910201

• Comparative activities of several nucleoside analogs against duck hepatitis B virus in vitro.

  Antimicrobial agents and chemotherapy 19900701

• Synthesis and anti-HIV evaluation of 2',3'-dideoxyribo-5-chloropyrimidine analogues: reduced toxicity of 5-chlorinated 2',3'-dideoxynucleosides.

  Journal of medicinal chemistry 19900601

• Susceptibility to nucleoside analogues of zidovudine-resistant isolates of human immunodeficiency virus.

  The American journal of medicine 19900521

• American Society for Biochemistry and Molecular Biology, the American Association of Immunologists, joint meeting. New Orleans, Louisiana, June 4-7, 1990. Abstracts 1-3659, TU1-TU35, indexes.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19900426

• Comparison of in vitro biological properties and mouse toxicities of three thymidine analogs active against human immunodeficiency virus.

  Antimicrobial agents and chemotherapy 19900401

• Comparative studies of 2',3'-didehydro-2',3'-dideoxythymidine (D4T) with other pyrimidine nucleoside analogues.

  Annals of the New York Academy of Sciences 19900101

• Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders.

  Journal of medicinal chemistry 19900101

• Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds.

  The Journal of biological chemistry 19890415

• HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy.

  Science (New York, N.Y.) 19890331

• 5-Chloro-substituted derivatives of 2', 3'-didehydro-2',3'-dideoxyuridine, 3'-fluoro-2',3'-dideoxyuridine and 3'-azido-2',3'-dideoxyuridine as anti-HIV agents.

  Biochemical pharmacology 19890315

• Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine.

  The Journal of experimental medicine 19890301

• Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells.

  Journal of medicinal chemistry 19890301

• 1-(3-cyano-2,3-dideoxy-beta-D-erythro-pentofuranosyl)thymine (cyanothymidine): synthesis and antiviral evaluation against human immunodeficiency virus.

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• 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent.

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• Antiviral agents with activity against human retroviruses.

  Journal of acquired immune deficiency syndromes 19890101

• Enhanced in vitro inhibition of HIV-1 replication by 3'-fluoro-3'-deoxythymidine compared to several other nucleoside analogs.

  AIDS research and human retroviruses 19881201

• Comparative activity of 2',3'-saturated and unsaturated pyrimidine and purine nucleosides against human immunodeficiency virus type 1 in peripheral blood mononuclear cells.

  Biochemical pharmacology 19881001

• The in vitro and in vivo anti-retrovirus activity, and intracellular metabolism of 3'-azido-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly dependent on the cell species.

  Biochemical pharmacology 19880301

• Ribavirin antagonizes inhibitory effects of pyrimidine 2',3'-dideoxynucleosides but enhances inhibitory effects of purine 2',3'-dideoxynucleosides on replication of human immunodeficiency virus in vitro.

  Antimicrobial agents and chemotherapy 19871001

• Potent and selective in vitro activity of 3'-deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus.

  Biochemical pharmacology 19870901

• 3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.

  Journal of medicinal chemistry 19870801

• The anti-HTLV-III (anti-HIV) and cytotoxic activity of 2',3'-didehydro-2',3'-dideoxyribonucleosides: a comparison with their parental 2',3'-dideoxyribonucleosides.

  Molecular pharmacology 19870701

• Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus.

  Antimicrobial agents and chemotherapy 19870601

• Potential anti-AIDS drugs. 2',3'-Dideoxycytidine analogues.

  Journal of medicinal chemistry 19870501

• Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses.

  Journal of medicinal chemistry 19870201

• Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.

  Biochemical and biophysical research communications 19870115