31252-42-3 | 4-Benzylpiperidine

Packsize	Purity	Availability	Price	Discounted Price
5g	99%	in stock	$14.00	$10.00
25g	99%	in stock	$39.00	$28.00
100g	99%	in stock	$98.00	$69.00

Description

• Catalog Number: AB66768
• Chemical Name: 4-Benzylpiperidine
• CAS Number: 31252-42-3
• Molecular Formula: C12H17N
• Molecular Weight: 175.27008000000004
• MDL Number: MFCD00006006
• SMILES: N1CCC(CC1)Cc1ccccc1
• NSC Number: 30346

Computed Properties

• Complexity: 132
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 2.5

Literature

• Structural, vibrational and DSC investigations of the bis-4-benzyl piperidinium tetraoxoselenate monohydrate crystal.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201

• Cocaine self-administration produces pharmacodynamic tolerance: differential effects on the potency of dopamine transporter blockers, releasers, and methylphenidate.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120601

• Selective suppression of cocaine- versus food-maintained responding by monoamine releasers in rhesus monkeys: benzylpiperazine, (+)phenmetrazine, and 4-benzylpiperidine.

  The Journal of pharmacology and experimental therapeutics 20090401

• Synthesis and pharmacological properties of new derivatives of 4-alkoxy-6-methyl-1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones.

  Acta poloniae pharmaceutica 20090101

• Novel sigma receptor ligands: synthesis and biological profile.

  Journal of medicinal chemistry 20070308

• JX401, A p38alpha inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast.

  Molecular pharmacology 20061001

• Discovery of a piperidine-4-carboxamide CCR5 antagonist (TAK-220) with highly potent Anti-HIV-1 activity.

  Journal of medicinal chemistry 20060504

• A novel class of sodium/calcium exchanger inhibitor: design, synthesis, and structure-activity relationships of 3,4-dihydro-2(1H)-quinazolinone derivatives.

  Bioorganic & medicinal chemistry 20050601

• Discovery of CC chemokine receptor-3 (CCR3) antagonists with picomolar potency.

  Journal of medicinal chemistry 20050324

• Synthesis and structure-activity relationships of 1-aralkyl-4-benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent sigma ligands.

  Journal of medicinal chemistry 20050113

• CCR5 antagonists as anti-HIV-1 agents. Part 2: Synthesis and biological evaluation of N-[3-(4-benzylpiperidin-1-yl)propyl]-N,N'-diphenylureas.

  Bioorganic & medicinal chemistry 20040501