-
A novel carbohydrate derived compound FCP5 causes DNA strand breaks and oxidative modifications of DNA bases in cancer cells.
Chemico-biological interactions 20150205
-
Pyrrolo[2,3-b]quinoxalines as inhibitors of firefly luciferase: their Cu-mediated synthesis and evaluation as false positives in a reporter gene assay.
Bioorganic & medicinal chemistry letters 20121015
-
Amide derivatives of benzene-sulfonanilide, pharmaceutical composition thereof and method for cancer treatment using the same (US20120095092).
Expert opinion on therapeutic patents 20121001
-
RCAI-84, 91, and 105-108, ureido and thioureido analogs of KRN7000: their synthesis and bioactivity for mouse lymphocytes to produce Th1-biased cytokines.
Bioorganic & medicinal chemistry 20120715
-
Conformational analysis, vibrational and NMR spectroscopic study of the methanesulfonamide-N,N'-1,2-ethanediylbis.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120601
-
Total synthesis of a marine alkaloid--rigidin E.
Marine drugs 20120601
-
Synthesis, evaluation and docking studies on 3-alkoxy-4-methanesulfonamido acetophenone derivatives as non ulcerogenic anti-inflammatory agents.
European journal of medicinal chemistry 20120301
-
Rosuvastatin blocks hERG current and prolongs cardiac repolarization.
Journal of pharmaceutical sciences 20120201
-
Managing atrial fibrillation in the elderly: critical appraisal of dronedarone.
Clinical interventions in aging 20120101
-
Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease.
Clinical Medicine Insights. Cardiology 20120101
-
N-[4-(4-Fluoro-phen-yl)-5-hy-droxy-methyl-6-isopropyl-pyrimidin-2-yl]-N-methyl-methane-sulfonamide.
Acta crystallographica. Section E, Structure reports online 20111201
-
The structure of NS-398 bound to cyclooxygenase-2.
Journal of structural biology 20111101
-
Methanesulfonamido-cyclohexylamine derivatives of 2,4-diaminopyrimidine as potent ALK inhibitors.
Bioorganic & medicinal chemistry letters 20110701
-
Synthesis and antibacterial activity of pentacyclines: a novel class of tetracycline analogs.
Journal of medicinal chemistry 20110609
-
Discovery of new chromone containing sulfonamides as potent inhibitors of bovine cytosolic carbonic anhydrase.
Bioorganic & medicinal chemistry 20110601
-
N,N'-Dibenzyl-N,N'-dimethyl-N''-(methyl-sulfon-yl)phospho-ric triamide.
Acta crystallographica. Section E, Structure reports online 20110601
-
Mild Pd-catalyzed N-arylation of methanesulfonamide and related nucleophiles: avoiding potentially genotoxic reagents and byproducts.
Organic letters 20110520
-
2-(N-Phenyl-methane-sulfonamido)-ethyl 1H-pyrrole-2-carboxyl-ate.
Acta crystallographica. Section E, Structure reports online 20110501
-
Clinical utility of rosuvastatin and other statins for cardiovascular risk reduction among the elderly.
Clinical interventions in aging 20110101
-
Application of molecular topology for the prediction of reaction yields and anti-inflammatory activity of heterocyclic amidine derivatives.
International journal of molecular sciences 20110101
-
Optimization of Benzoisothiazole dioxide inhibitory activity of the NS5B polymerase of HCV genotype 4 using ligand-steered homological modeling, reaction-driven scaffold-hopping and Enovo workflow.
Bioinformation 20110101
-
A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.
Journal of medicinal chemistry 20101111
-
Expanding the diversity of allosteric bcr-abl inhibitors.
Journal of medicinal chemistry 20101014
-
Impact of dronedarone in atrial fibrillation and flutter on stroke reduction.
Clinical interventions in aging 20100101
-
Studies of benzothiadiazine derivatives as hepatitis C virus NS5B polymerase inhibitors using 3D-QSAR, molecular docking and molecular dynamics.
Current medicinal chemistry 20100101
-
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides.
Bioorganic & medicinal chemistry letters 20091001
-
Bis(tetra-phenyl-phospho-nium) tris-[N-(methyl-sulfon-yl)dithio-carbimato(2-)-κS,S']stannate(IV).
Acta crystallographica. Section E, Structure reports online 20091001
-
Synthesis, antiviral and anticancer activity of some novel thioureas derived from N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide.
European journal of medicinal chemistry 20090901
-
Novel indoline-based acyl-CoA: cholesterol acyltransferase inhibitor: Effects of introducing a methanesulfonamide group on physicochemical properties and biological activities.
Bioorganic & medicinal chemistry 20090815
-
Regulation of the apoptosis-inducing kinase DRAK2 by cyclooxygenase-2 in colorectal cancer.
British journal of cancer 20090804
-
Synthesis, anticancer, and anti-inflammatory activity evaluation of methanesulfonamide and amidine derivatives of 3,4-diaryl-2-imino-4-thiazolines.
Molecular diversity 20090801
-
Development and validation of an LC-MS/MS method for determination of methanesulfonamide in human urine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715
-
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure-activity relationships of benzothiazine-substituted quinolinediones.
Bioorganic & medicinal chemistry letters 20090701
-
Methanesulfonamide: a cosolvent and a general acid catalyst in sharpless asymmetric dihydroxylations.
The Journal of organic chemistry 20090417
-
Cytotoxic activity of platinum(II) and palladium(II) complexes of N-3-pyridinylmethanesulfonamide: the influence of electroporation.
Zeitschrift fur Naturforschung. C, Journal of biosciences 20090101
-
Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis.
PloS one 20090101
-
Long-term use of rosuvastatin: a critical risk benefit appraisal and comparison with other antihyperlipidemics.
Drug, healthcare and patient safety 20090101
-
An experimental and theoretical study of dipole moments of N-[4-(9-acridinylamino)-3-methoxyphenyl]methanesulfonamide.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080901
-
(4R)-4-[(1R)-1,2-Dihydroxy-ethyl]-1-[(1R)-1-phenyl-ethyl]pyrrolidin-2-one.
Acta crystallographica. Section E, Structure reports online 20080901
-
Clinical efficacy and safety of statins in managing cardiovascular risk.
Vascular health and risk management 20080401
-
beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 1. Design, synthesis, and lead identification.
Bioorganic & medicinal chemistry letters 20080201
-
Methyl 2-(N-ethyl-methane-sulfonamido)benzoate.
Acta crystallographica. Section E, Structure reports online 20080201
-
Synthesis and biological evaluation of novel sulfonanilide compounds as antiproliferative agents for breast cancer.
Journal of combinatorial chemistry 20080101
-
A new strategy for the synthesis of benzylic sulfonamides: palladium-catalyzed arylation and sulfonamide metathesis.
The Journal of organic chemistry 20071012
-
Discovery of a highly active ligand of human pregnane x receptor: a case study from pharmacophore modeling and virtual screening to 'in vivo' biological activity.
Molecular pharmacology 20070901
-
Optimization of triaryl bis-sulfones as cannabinoid-2 receptor ligands.
Bioorganic & medicinal chemistry letters 20070701
-
A single component ratiometric pH probe with long wavelength excitation of europium emission.
Chemical communications (Cambridge, England) 20070207
-
Synthesis and biological evaluation of methanesulfonamide analogues of rofecoxib: Replacement of methanesulfonyl by methanesulfonamido decreases cyclooxygenase-2 selectivity.
Bioorganic & medicinal chemistry 20070115
-
Inhibition of human phenol and estrogen sulfotransferase by certain non-steroidal anti-inflammatory agents.
Current drug metabolism 20061001
-
Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides.
Bioorganic & medicinal chemistry letters 20051201
-
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with N-hydroxysulfamides--a new zinc-binding function in the design of inhibitors.
Bioorganic & medicinal chemistry letters 20050502
-
Structural determinants of HERG channel block by clofilium and ibutilide.
Molecular pharmacology 20040801
-
[Synthesis and anti-inflammatory activity of N-(4-arylamidophenyl) methanesulfonamide derivatives].
Yao xue xue bao = Acta pharmaceutica Sinica 20040701
-
Methanesulfonamide group at position-4 of the C-5-phenyl ring of 1,5-diarylpyrazole affords a potent class of cyclooxygenase-2 (COX-2) inhibitors.
Bioorganic & medicinal chemistry letters 20040405
-
N-4-Substituted-benzyl-N'-tert-butylbenzyl thioureas as vanilloid receptor ligands: investigation on the role of methanesulfonamido group in antagonistic activity.
Bioorganic & medicinal chemistry letters 20040209
-
Differential recovery of action potential duration and HERG currents from the effects of two methanesulfonamide class III antiarrhythmic agents, KCB-328 and dofetilide.
Journal of cardiovascular pharmacology 20031101
-
Variations of acidic functions at position 2 and substituents at positions 4, 5 and 6 of the indole moiety and their effect on NMDA-glycine site affinity.
European journal of medicinal chemistry 20031001
-
Synthesis and prostaglandin synthase inhibitory activity of new aromatic O-alkyloxime ethers substituted with methylsulfonamido or methylsulfonyl groups on their aliphatic portion.
Farmaco (Societa chimica italiana : 1989) 20030901
-
Acetic acid-derived prostaglandin-dependent colonic adaptive cytoprotection is preserved in chronic colitis: role of cyclo-oxygenase.
International journal of colorectal disease 20030501
-
[Anti-arrhythmic action of N-(aminoalkylene) derivatives of indoline-2,3-diones and 1,2-benzene-dicarboxiamides].
Medicina (Kaunas, Lithuania) 20020101
-
Substituted indole-5-carboxamides and -acetamides as potent nonpeptide GnRH receptor antagonists.
Bioorganic & medicinal chemistry letters 20010709