31519-22-9 | 1,4-Dihydroxy-2-naphthoic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	98%(HPLC)	in stock	$24.00	$17.00
5g	95%	in stock	$50.00	$35.00
25g	98%	in stock	$126.00	$88.00
100g	95%	in stock	$449.00	$315.00

Description

• Catalog Number: AB57498
• Chemical Name: 1,4-Dihydroxy-2-naphthoic acid
• CAS Number: 31519-22-9
• Molecular Formula: C11H8O4
• Molecular Weight: 204.1788
• MDL Number: MFCD00010370
• SMILES: OC(=O)c1cc(O)c2c(c1O)cccc2

Computed Properties

• Complexity: 253
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 1
• XLogP3: 2.5

Literature

• Editor's Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure-Activity Relationships and Receptor Modeling.

  Toxicological sciences : an official journal of the Society of Toxicology 20170201

• Vitamins A & D inhibit the growth of mycobacteria in radiometric culture.

  PloS one 20120101

• Safety of high doses of Propionibacterium freudenreichii ET-3 culture in healthy adult subjects.

  Regulatory toxicology and pharmacology : RTP 20110701

• Safety evaluation of Propionibacterium freudenreichii ET-3 culture.

  Regulatory toxicology and pharmacology : RTP 20110701

• Cultivation of E. coli carrying a plasmid-based Measles vaccine construct (4.2 kbp pcDNA3F) employing medium optimisation and pH-temperature induction techniques.

  Microbial cell factories 20110101

• Evolutionary relationships of microbial aromatic prenyltransferases.

  PloS one 20110101

• Substituted naphthoquinones as novel amino acid sensitive reagents for the detection of latent fingermarks on paper surfaces.

  Talanta 20101015

• Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity.

  Molecular pharmacology 20101001

• The bifidogenic growth stimulator inhibits the growth and respiration of Helicobacter pylori.

  Helicobacter 20101001

• Graph-based analysis of the metabolic exchanges between two co-resident intracellular symbionts, Baumannia cicadellinicola and Sulcia muelleri, with their insect host, Homalodisca coagulata.

  PLoS computational biology 20100901

• Suppressive effects of 1,4-dihydroxy-2-naphthoic acid administration on bone resorption.

  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20100801

• UBIAD1 mutation alters a mitochondrial prenyltransferase to cause Schnyder corneal dystrophy.

  PloS one 20100101

• The complete genome of Propionibacterium freudenreichii CIRM-BIA1, a hardy actinobacterium with food and probiotic applications.

  PloS one 20100101

• Biosynthetic origin of 2,3-epoxysesamone in a Sesamum indicum hairy root culture.

  Bioscience, biotechnology, and biochemistry 20091101

• Role of menaquinone biosynthesis genes in selenate reduction by Enterobacter cloacae SLD1a-1 and Escherichia coli K12.

  Environmental microbiology 20090101

• Electrochemical regulation of the end-product profile in Propionibacterium freudenreichii ET-3 with an endogenous mediator.

  Biotechnology and bioengineering 20081015

• Structure-based discovery of a novel non-peptidic small molecular inhibitor of caspase-3.

  Bioorganic & medicinal chemistry 20080501

• The AAE14 gene encodes the Arabidopsis o-succinylbenzoyl-CoA ligase that is essential for phylloquinone synthesis and photosystem-I function.

  The Plant journal : for cell and molecular biology 20080401

• 2,5-dihydroxybenzyl and (1,4-dihydroxy-2-naphthyl)methyl, novel reductively armed photocages for the hydroxyl moiety.

  The Journal of organic chemistry 20071123

• Discovery of 1,4-dihydroxy-2-naphthoate [corrected] prenyltransferase inhibitors: new drug leads for multidrug-resistant gram-positive pathogens.

  Journal of medicinal chemistry 20070823

• Characteristic of milk whey culture with Propionibacterium freudenreichii ET-3 and its application to the inflammatory bowel disease therapy.

  Inflammopharmacology 20070601

• Production of extracellular bifidogenic growth stimulator by anaerobic and aerobic cultivations of several propionibacterial strains.

  Journal of bioscience and bioengineering 20070501

• Cloning, expression, purification, crystallization and preliminary X-ray crystallographic study of DHNA synthetase from Geobacillus kaustophilus.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20070201

• Mutations in the UBIAD1 gene, encoding a potential prenyltransferase, are causal for Schnyder crystalline corneal dystrophy.

  PloS one 20070101

• Optimal aerobic cultivation method for 1,4-dihydroxy-2-naphthoic acid production by Propionibacterium freudenreichii ET-3.

  Journal of bioscience and bioengineering 20060901

• Aerobic culture of Propionibacterium freudenreichii ET-3 can increase production ratio of 1,4-dihydroxy-2-naphthoic acid to menaquinone.

  Journal of bioscience and bioengineering 20060601

• Propionibacterium freudenreichii component 1.4-dihydroxy-2-naphthoic acid (DHNA) attenuates dextran sodium sulphate induced colitis by modulation of bacterial flora and lymphocyte homing.

  Gut 20060501

• The secondary electron acceptor of photosystem I in Gloeobacter violaceus PCC 7421 is menaquinone-4 that is synthesized by a unique but unknown pathway.

  FEBS letters 20050704

• A derivative of the menaquinone precursor 1,4-dihydroxy-2-naphthoate is involved in the reductive transformation of carbon tetrachloride by aerobically grown Shewanella oneidensis MR-1.

  Applied microbiology and biotechnology 20040201

• Isolation and identification of a new bifidogenic growth stimulator produced by Propionibacterium freudenreichii ET-3.

  Bioscience, biotechnology, and biochemistry 20020301