321661-62-5 | Cytosporone B

Packsize	Purity	Availability	Price	Discounted Price
2mg	98%	in stock	$15.00	$11.00
5mg	98%	in stock	$26.00	$18.00
25mg	98%	in stock	$65.00	$46.00
50mg	98%	in stock	$108.00	$76.00
250mg	98%	in stock	$465.00	$325.00
1g	98%	in stock	$1,086.00	$760.00

Description

• Catalog Number: AV18354
• Chemical Name: Cytosporone B
• CAS Number: 321661-62-5
• Molecular Formula: C18H26O5
• Molecular Weight: 322.3960
• MDL Number: MFCD12912406
• SMILES: CCCCCCCC(=O)c1c(O)cc(cc1CC(=O)OCC)O

Computed Properties

• Complexity: 368
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 23
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 11
• XLogP3: 4.6

Literature

• Epigenetic tailoring for the production of anti-infective cytosporones from the marine fungus Leucostoma persoonii.

  Marine drugs 20120401

• Targeting NR4A1 (TR3) in cancer cells and tumors.

  Expert opinion on therapeutic targets 20110201

• A unique pharmacophore for activation of the nuclear orphan receptor Nur77 in vivo and in vitro.

  Cancer research 20100501

• Cytosporone B is an agonist for nuclear orphan receptor Nur77.

  Nature chemical biology 20080901

• Structural basis for the cell-specific activities of the NGFI-B and the Nurr1 ligand-binding domain.

  The Journal of biological chemistry 20050513

• The Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathway.

  Cell 20030613

• Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors.

  Nature 20030529