32791-84-7 | Panaxatriol

Packsize	Purity	Availability	Price	Discounted Price
25mg	≥95%	in stock	$79.00	$55.00
50mg	≥95%	in stock	$130.00	$91.00
100mg	≥95%	in stock	$197.00	$138.00

Description

• Catalog Number: AF56922
• Chemical Name: Panaxatriol
• CAS Number: 32791-84-7
• Molecular Formula: C30H52O4
• Molecular Weight: 476.7315
• MDL Number: MFCD00210541
• SMILES: OC1CC2(C)C(C3(C1C(C)(C)C(O)CC3)C)CC(C1C2(C)CCC1C1(C)CCCC(O1)(C)C)O

Computed Properties

• Complexity: 823
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 11
• Heavy Atom Count: 34
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 1
• XLogP3: 5.5

Literature

• Ginsenoside Re: Its chemistry, metabolism and pharmacokinetics.

  Chinese medicine 20120101

• Ginsenosides as Anticancer Agents: In vitro and in vivo Activities, Structure-Activity Relationships, and Molecular Mechanisms of Action.

  Frontiers in pharmacology 20120101

• Protective effect of panaxatriol saponins extracted from Panax notoginseng against MPTP-induced neurotoxicity in vivo.

  Journal of ethnopharmacology 20110127

• Panax notoginseng Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Pharmacokinetics study of bio-adhesive tablet of Panax notoginseng saponins.

  International archives of medicine 20110101

• Stuck at the bench: Potential natural neuroprotective compounds for concussion.

  Surgical neurology international 20110101

• Effects of American ginseng (Panax quinquefolius) on neurocognitive function: an acute, randomised, double-blind, placebo-controlled, crossover study.

  Psychopharmacology 20101001

• The effects of ginseng total saponin, panaxadiol and panaxatriol on ischemia/reperfusion injury in isolated rat heart.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100601

• Progression from chronic atrophic gastritis to gastric cancer; tangle, toggle, tackle with Korea red ginseng.

  Journal of clinical biochemistry and nutrition 20100501

• Panaxatriol saponins extracted from Panax notoginseng induces thioredoxin-1 and prevents 1-methyl-4-phenylpyridinium ion-induced neurotoxicity.

  Journal of ethnopharmacology 20100203

• Simultaneous determination of three major bioactive saponins of Panax notoginseng using liquid chromatography-tandem mass spectrometry and a pharmacokinetic study.

  Chinese medicine 20100101

• Pharmacology of ginsenosides: a literature review.

  Chinese medicine 20100101

• Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines.

  Chinese medicine 20100101

• Determination of 20(S)-ginsenoside Rh1 and its aglycone 20(S)-protopanaxatriol in rat plasma by sensitive LC-APCI-MS method and its application to pharmacokinetic study.

  European journal of mass spectrometry (Chichester, England) 20090101

• Bioactivity-guided identification and cell signaling technology to delineate the immunomodulatory effects of Panax ginseng on human promonocytic U937 cells.

  Journal of translational medicine 20090101

• Influence of ginsenoside Rg1, a panaxatriol saponin from Panax notoginseng, on renal fibrosis in rats with unilateral ureteral obstruction.

  Journal of Zhejiang University. Science. B 20081101

• Sanchi for acute ischaemic stroke.

  The Cochrane database of systematic reviews 20081008

• Effect of panaxatriol on hematogenesis and granulocyte-macrophage colony stimulating factor in radiation injured mice.

  Saudi medical journal 20071201

• In Vivo radioprotective effect of Panax ginseng C.A. Meyer and identification of active ginsenosides.

  Phytotherapy research : PTR 20060501

• Modulating effect of ginseng saponins on heterologously expressed HERG currents in Xenopus oocytes.

  Acta pharmacologica Sinica 20050501

• [Effect of panaxadiol saponin and panaxtrol saponin on proliferation of human bone marrow hemopoietic progenitor cells].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040201

• Effect of ginseng saponins on the recombinant serotonin type 3A receptor expressed in xenopus oocytes: implication of possible application as an antiemetic.

  Journal of alternative and complementary medicine (New York, N.Y.) 20030801

• Modification of radiation response in mice by ginsenosides, active components of Panax ginseng.

  In vivo (Athens, Greece) 20030101

• [Study on antiradiation effect of panaxatriol].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20021101

• [Protective effects and its mechanism of panaxatriol saponins isolated from Panax notoginseng on cerebral ischemia].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20020501

• Absolute structure of panaxytriol.

  Chemical & pharmaceutical bulletin 20020101

• Effects of ginsenosides from Panax ginseng on cell-to-cell communication function mediated by gap junctions.

  Planta medica 20010701