338-69-2 | (2R)-2-aminopropanoic acid

Packsize	Purity	Availability	Price	Discounted Price
10g	97%	in stock	$6.00	$4.00
25g	97%	in stock	$12.00	$9.00
100g	97%	in stock	$36.00	$25.00
500g	97%	in stock	$43.00	$30.00

Description

• Catalog Number: AB45837
• Chemical Name: (2R)-2-aminopropanoic acid
• CAS Number: 338-69-2
• Molecular Formula: C3H7NO2
• Molecular Weight: 89.0932
• MDL Number: MFCD00008077
• SMILES: C[C@H](C(=O)O)N

Computed Properties

• Complexity: 61.8
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: -3

Literature

• Rebamipide suppresses 5-fluorouracil-induced cell death via the activation of Akt/mTOR pathway and regulates the expression of Bcl-2 family proteins.

  Toxicology in vitro : an international journal published in association with BIBRA 20180201

• Cytotoxicity and immunomodulatory effects of sol-gel combustion based titanium dioxide (TiO(2)) particles of large surface area on RAW 264.7 macrophages.

  Toxicology in vitro : an international journal published in association with BIBRA 20170901

• Characterization of two peptides isolated from the venom of social wasp Chartergellus communis (Hymenoptera: Vespidae): Influence of multiple alanine residues and C-terminal amidation on biological effects.

  Peptides 20170901

• Alanine to valine substitutions in the pore helix IIIP1 and linker-helix IIIL45 confer cockroach sodium channel resistance to DDT and pyrethroids.

  Neurotoxicology 20170501

• Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20161001

• Naturally Inspired Peptide Leads: Alanine Scanning Reveals an Actin-Targeting Thiazole Analogue of Bisebromoamide.

  Chembiochem : a European journal of chemical biology 20160902

• Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining.

  Oncotarget 20150929

• Multiple biomarkers of the cytotoxicity induced by BDE-47 in human embryonic kidney cells.

  Chemosphere 20150501

• The influence of amino acid sequence on structure and morphology of polydiacetylene containing peptide fibres.

  Soft matter 20150204

• Identification of a unique radical S-adenosylmethionine methylase likely involved in methanopterin biosynthesis in Methanocaldococcus jannaschii.

  Journal of bacteriology 20140901

• The peptide Z-Aib-Aib-Aib-L-Ala-OtBu.

  Acta crystallographica. Section C, Structural chemistry 20140401

• A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20140301

• Conformational study of N-methylated alanine peptides and design of Abeta inhibitor.

  Indian journal of biochemistry & biophysics 20140201

• Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain.

  Journal of medicinal chemistry 20131024

• A phase 3 trial of semagacestat for treatment of Alzheimer's disease.

  The New England journal of medicine 20130725

• Exposure to 2,4-dichlorophenoxyacetic acid alters glucose metabolism in immature rat Sertoli cells.

  Reproductive toxicology (Elmsford, N.Y.) 20130701

• Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE).

  British journal of pharmacology 20130601

• Harmful effects of usnic acid on hepatic metabolism.

  Chemico-biological interactions 20130425

• Copper(II) complexes of neurokinin A with point mutation (S5A) and products of copper-catalyzed oxidation; role of serine residue in peptides containing neurokinin A sequence.

  Journal of inorganic biochemistry 20130401

• Synthesis and evaluation against hepatitis C virus of 7-deaza analogues of 2'-C-methyl-6-O-methyl guanosine nucleoside and L-Alanine ester phosphoramidates.

  Bioorganic & medicinal chemistry letters 20130401

• Fc receptor-γ subunits with both polar or non-polar amino acids at position of T22 are capable of restoring surface expression of the high-affinity IgE receptor and degranulation in γ subunit-deficient rat basophilic leukemia cells.

  Molecular immunology 20130301

• Action and timing of BacC and BacD in the late stages of biosynthesis of the dipeptide antibiotic bacilysin.

  Biochemistry 20130205

• Synthesis of peptide-cellulose conjugate mediated by a soluble cellulose derivative having β-Ala esters.

  International journal of biological macromolecules 20130201

• Disposition and metabolism of safinamide, a novel drug for Parkinson's disease, in healthy male volunteers.

  Pharmacology 20130101

• Influence of alanine uptake on Staphylococcus aureus surface charge and its susceptibility to two cationic antibacterial agents, nisin and low molecular weight chitosan.

  Food chemistry 20121215

• Increase in antioxidant effect of ginsenoside Re-alanine mixture by Maillard reaction.

  Food chemistry 20121215

• PPARγ2 Pro12Ala polymorphism is associated with improved lipoprotein lipase functioning in adipose tissue of insulin resistant obese women.

  Gene 20121215

• The enzymology of alanine aminotransferase (AlaAT) isoforms from Hordeum vulgare and other organisms, and the HvAlaAT crystal structure.

  Archives of biochemistry and biophysics 20121201

• Biochemical characterization of two Azotobacter vinelandii FKBPs and analysis of their interaction with the small subunit of carbamoyl phosphate synthetase.

  Molecular biology reports 20121201

• D-amino acid-induced expression of D-amino acid oxidase in the yeast Schizosaccharomyces pombe.

  Current microbiology 20121201

• Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin.

  The Journal of biological chemistry 20121130

• Electrospray ionization tandem mass spectrometry of protonated and alkali-cationized Boc-N-protected hybrid peptides containing repeats of D-Ala-APyC and APyC-D-Ala: formation of [b(n-1) + OCH3 + Na]+ and [b(n-1) + OH + Na]+ ions.

  Rapid communications in mass spectrometry : RCM 20121130

• Solubility and solution stability studies of different amino acid prodrugs of bromhexine.

  Drug development and industrial pharmacy 20121101

• Investigating the parameters affecting the adsorption of amino acids onto AgCl nanoparticles with different surface charges.

  Amino acids 20121101

• Cyclic enediyne-amino acid chimeras as new aminopeptidase N inhibitors.

  Amino acids 20121101

• Functional screening of antibiotic resistance genes from human gut microbiota reveals a novel gene fusion.

  FEMS microbiology letters 20121101

• Rebamipide attenuates pain severity and cartilage degeneration in a rat model of osteoarthritis by downregulating oxidative damage and catabolic activity in chondrocytes.

  Osteoarthritis and cartilage 20121101

• Proconvertase proteolytic processing of an enzymatically active myeloperoxidase precursor.

  Archives of biochemistry and biophysics 20121101

• Effects of supplementation on food intake, body weight and hepatic metabolites in the citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mouse model of human citrin deficiency.

  Molecular genetics and metabolism 20121101

• Comparison of the structures and stabilities of coiled-coil proteins containing hexafluoroleucine and t-butylalanine provides insight into the stabilizing effects of highly fluorinated amino acid side-chains.

  Protein science : a publication of the Protein Society 20121101

• Identification of the critical amino acid residues of immunoglobulin E and immunoglobulin G epitopes in β-lactoglobulin by alanine scanning analysis.

  Journal of dairy science 20121101

• A detailed biochemical characterization of phosphopantothenate synthetase, a novel enzyme involved in coenzyme A biosynthesis in the Archaea.

  Extremophiles : life under extreme conditions 20121101

• Androgen-responsive and nonresponsive prostate cancer cells present a distinct glycolytic metabolism profile.

  The international journal of biochemistry & cell biology 20121101

• Characterization and identification of alanine to serine sequence variants in an IgG4 monoclonal antibody produced in mammalian cell lines.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121101

• Synthesis of β-C-galactosyl D- and L-alanines.

  Organic & biomolecular chemistry 20121028

• Structural evolution of amino acid crystals under stress from a non-empirical density functional.

  Journal of physics. Condensed matter : an Institute of Physics journal 20121024

• Serum stability of selected decapeptide agonists of KISS1R using pseudopeptides.

  Bioorganic & medicinal chemistry letters 20121015

• Altered allosteric regulation of muscle 6-phosphofructokinase causes Tarui disease.

  Biochemical and biophysical research communications 20121012

• Cyclization of peptides by using selenolanthionine bridges.

  Angewandte Chemie (International ed. in English) 20121008

• High yielding synthesis of N-ethyl dehydroamino acids.

  Amino acids 20121001

• Lipid metabolism in pigs fed supplemental conjugated linoleic acid and/or dietary arginine.

  Amino acids 20121001

• Novel emissive bio-inspired non-proteinogenic coumarin-alanine amino acid: fluorescent probe for polyfunctional systems.

  Amino acids 20121001

• Synthesis and evaluation of 18F labeled alanine derivatives as potential tumor imaging agents.

  Nuclear medicine and biology 20121001

• Crystal structure of the O intermediate of the Leu93→Ala mutant of bacteriorhodopsin.

  Proteins 20121001

• Binding mechanism between Hsp90 and Sgt1 explored by homology modeling and molecular dynamics simulations in rice.

  Journal of molecular modeling 20121001

• Inflammatory cytokines in vitro production are associated with Ala16Val superoxide dismutase gene polymorphism of peripheral blood mononuclear cells.

  Cytokine 20121001

• Rescue of a pathogenic mutant human glucagon receptor by pharmacological chaperones.

  Journal of molecular endocrinology 20121001

• Bacterial responses to a simulated colon tumor microenvironment.

  Molecular & cellular proteomics : MCP 20121001

• Ser(262) determines the chloride-dependent colour tuning of a new halorhodopsin from Haloquadratum walsbyi.

  Bioscience reports 20121001

• Alanine scanning mutagenesis of a high-affinity nitrate transporter highlights the requirement for glycine and asparagine residues in the two nitrate signature motifs.

  The Biochemical journal 20121001

• The effects on metabolic clearance when administering a potent CYP3A autoinducer with the prototypic CYP3A inhibitor, ketoconazole.

  Drug metabolism and disposition: the biological fate of chemicals 20121001

• Water interaction differences determine the relative energetic stability of the polyproline II conformation of the alanine dipeptide in aqueous environments.

  Biopolymers 20121001

• MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma.

  Oncology reports 20121001

• A series of amino acid functionalized tripodal hexaamide anion receptors: ion-pair-assisted capped-cleft formation by a pentafluorophenyl-functionalized amide.

  Chemistry, an Asian journal 20121001

• Design of protein congeners containing β-cyclopropylalanine.

  Molecular bioSystems 20121001

• Growth and characterization of L-alanine cadmium bromide a semiorganic nonlinear optical crystals.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001

• Identification of key residues for the binding of glucagon to the N-terminal domain of its receptor: an alanine scan and modeling study.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20121001

• Behavior of mixed formulation of metalaxyl and dimethomorph in grape and soil under field conditions.

  Ecotoxicology and environmental safety 20121001

• Synthesis of pentasaccharides corresponding to the glycoform II of the outer core region of the Pseudomonas aeruginosa lipopolysaccharide.

  Carbohydrate research 20121001

• Molecular dynamics of glycine ions in alanine doped TGS single crystal as probed by polarized laser Raman spectroscopy.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001

• The effect of safinamide, a novel drug for Parkinson's disease, on pressor response to oral tyramine: a randomized, double-blind, clinical trial.

  Clinical pharmacology and therapeutics 20121001

• Small organic solutes in sticky droplets from orb webs of the spider Zygiella atrica (Araneae; Araneidae): β-alaninamide is a novel and abundant component.

  Chemistry & biodiversity 20121001

• Localization of inhibitory antibodies to the biotin domain of human pyruvate carboxylase.

  Hybridoma (2005) 20121001

• Presynaptic facilitation of glutamate release in the basolateral amygdala: a mechanism for the anxiogenic and seizurogenic function of GluK1 receptors.

  Neuroscience 20120927

• Curvopeptin: a new lanthionine-containing class III lantibiotic and its co-substrate promiscuous synthetase.

  Chembiochem : a European journal of chemical biology 20120924

• Biosynthesis of the class III lantipeptide catenulipeptin.

  ACS chemical biology 20120921

• The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor.

  The Journal of biological chemistry 20120914

• Self-assembly of folic acid: a chiral-aligning medium for enantiodiscrimination of organic molecules in an aqueous environment.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20120910

• Native state conformational heterogeneity of HP35 revealed by time-resolved FRET.

  The journal of physical chemistry. B 20120906

• The Red clover necrotic mosaic virus capsid protein N-terminal lysine-rich motif is a determinant of symptomatology and virion accumulation.

  Molecular plant pathology 20120901

• Alanine or aspartic acid substitutions at serine23/24 of cardiac troponin I decrease thin filament activation, with no effect on crossbridge detachment kinetics.

  Archives of biochemistry and biophysics 20120901

• Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.

  Neurochemical research 20120901

• Reversible generalized dystonia and encephalopathy from thiamine transporter 2 deficiency.

  Movement disorders : official journal of the Movement Disorder Society 20120901

• D-alanylation of lipoteichoic acids confers resistance to cationic peptides in group B streptococcus by increasing the cell wall density.

  PLoS pathogens 20120901

• Defining TNF-α and IL-1β induced nascent proteins: combining bio-orthogonal non-canonical amino acid tagging and proteomics.

  Journal of immunological methods 20120831

• Type 6 secretion dynamics within and between bacterial cells.

  Science (New York, N.Y.) 20120817

• Function of the D-alanine:D-alanine ligase lid loop: a molecular modeling and bioactivity study.

  Journal of medicinal chemistry 20120809

• Total synthesis of dendrobate alkaloid (+)-241D, isosolenopsin and isosolenopsin A: application of a gold-catalyzed cyclization.

  Organic & biomolecular chemistry 20120807

• Discriminating D-amino acid-containing peptide epimers by radical-directed dissociation mass spectrometry.

  Analytical chemistry 20120807

• Synthesis of protected 2-pyrrolylalanine for peptide chemistry and examination of its influence on prolyl amide isomer equilibrium.

  The Journal of organic chemistry 20120803

• Stable triazolylphosphonate analogues of phosphohistidine.

  Amino acids 20120801

• Fast volumetric imaging of ethanol metabolism in rat liver with hyperpolarized [1-(13) C]pyruvate.

  NMR in biomedicine 20120801

• Urine metabolomics analysis for biomarker discovery and detection of jaundice syndrome in patients with liver disease.

  Molecular & cellular proteomics : MCP 20120801

• Circulating metabolite predictors of glycemia in middle-aged men and women.

  Diabetes care 20120801

• Mutations in MexB that affect the efflux of antibiotics with cytoplasmic targets.

  FEMS microbiology letters 20120801

• Ring substituents on substituted benzamide ligands indirectly mediate interactions with position 7.39 of transmembrane helix 7 of the D4 dopamine receptor.

  The Journal of pharmacology and experimental therapeutics 20120801

• Limited effect on NS3-NS4A protein cleavage after alanine substitutions within the immunodominant HLA-A2-restricted epitope of the hepatitis C virus genotype 3a non-structural 3/4A protease.

  The Journal of general virology 20120801

• Constitutively active mutant gives novel insights into the mechanism of bitter taste receptor activation.

  Journal of neurochemistry 20120801

• Metabolite profiles of rice cultivars containing bacterial blight-resistant genes are distinctive from susceptible rice.

  Acta biochimica et biophysica Sinica 20120801

• Dynamic nuclear polarization-enhanced ¹H-¹³C double resonance NMR in static samples below 20 K.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20120801

• X-ray diffraction and Raman study of DL-alanine at high pressure: revision of phase transitions.

  Acta crystallographica. Section B, Structural science 20120801

• Nicotine exposure during adolescence leads to short- and long-term changes in spike timing-dependent plasticity in rat prefrontal cortex.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120801

• Continuous β-turn fold of an alternating alanyl/homoalanyl peptide nucleic acid.

  Acta crystallographica. Section D, Biological crystallography 20120801

• Binding of the unreactive substrate analog L-2-amino-3-guanidinopropionic acid (dinor-L-arginine) to human arginase I.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20120801

• Gender-dependent metabolic remodeling during heart preservation in cardioplegic celsior and histidine buffer solution.

  Journal of cardiovascular pharmacology 20120801

• On the output factor measurements of the CyberKnife iris collimator small fields: Experimental determination of the k(Q(clin),Q(msr) ) (f(clin),f(msr) ) correction factors for microchamber and diode detectors.

  Medical physics 20120801

• Metabolomic analyses of blood plasma after oral administration of D-glucosamine hydrochloride to dogs.

  Marine drugs 20120801

• X-ray spectroscopy of blocked alanine in water solution from supermolecular and supermolecular-continuum solvation models: a first-principles study.

  Physical chemistry chemical physics : PCCP 20120721

• Rebamipide induces dendritic cell recruitment to N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-exposed rat gastric mucosa based on IL-1β upregulation.

  Biochemical and biophysical research communications 20120720

• Functional significance of conserved cysteines in the human organic cation transporter 2.

  American journal of physiology. Renal physiology 20120715

• The three-dimensional structural basis of type II hyperprolinemia.

  Journal of molecular biology 20120713

• The roles of tryptophans in primer synthesis by the DNA primase of bacteriophage T7.

  The Journal of biological chemistry 20120706

• Theoretical and experimental study of valence photoelectron spectrum of D,L-alanine amino acid.

  The journal of physical chemistry. A 20120705

• The role of the second and third extracellular loops of the adenosine A1 receptor in activation and allosteric modulation.

  Biochemical pharmacology 20120701

• A cis-acting five-amino-acid motif controls targeting of ABCC2 to the apical plasma membrane domain.

  Journal of cell science 20120701

• Effects of nucleotide analogs at the P2X3 receptor and its mutants identify the agonist binding pouch.

  Molecular pharmacology 20120701

• Effect of multiple cysteine substitutions on the functionality of human multidrug resistance protein 1 expressed in human embryonic kidney 293 cells: identification of residues essential for function.

  Drug metabolism and disposition: the biological fate of chemicals 20120701

• Identification of beta-amyloid-binding sites on transthyretin.

  Protein engineering, design & selection : PEDS 20120701

• Polyalanine-independent conformational conversion of nuclear poly(A)-binding protein 1 (PABPN1).

  The Journal of biological chemistry 20120629

• Plasma sarcosine does not distinguish early and advanced stages of prostate cancer.

  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20120628

• On the molecular mechanism of stabilization of proteins by cosolvents: role of Lifshitz electrodynamic forces.

  Langmuir : the ACS journal of surfaces and colloids 20120626

• Total synthesis of (-)-dysiherbaine.

  Chemical communications (Cambridge, England) 20120625

• Functional determinants of human enteric α-defensin HD5: crucial role for hydrophobicity at dimer interface.

  The Journal of biological chemistry 20120622

• Prenylation at the indole ring leads to a significant increase of cytotoxicity of tryptophan-containing cyclic dipeptides.

  Bioorganic & medicinal chemistry letters 20120615

• Phosphorylation and activation of nuclear Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP-N/PPM1E) by Ca2+/calmodulin-dependent protein kinase I (CaMKI).

  Biochemical and biophysical research communications 20120615

• Chain-length and mode-delocalization dependent amide-I anharmonicity in peptide oligomers.

  The Journal of chemical physics 20120607

• Gadolinium modulates gentamicin uptake via an endocytosis-independent pathway in HK-2 human renal proximal tubular cell line.

  European journal of pharmacology 20120605

• Loop residues and catalysis in OMP synthase.

  Biochemistry 20120605

• Lack of effect of brivanib on the pharmacokinetics of midazolam, a CYP3A4 substrate, administered intravenously and orally in healthy participants.

  Journal of clinical pharmacology 20120601

• Dietary L-arginine supplementation enhances placental growth and reproductive performance in sows.

  Amino acids 20120601

• Semagacestat pharmacokinetics are not significantly affected by formulation, food, or time of dosing in healthy participants.

  Journal of clinical pharmacology 20120601

• Cross-linking of wheat gluten proteins during production of hard pretzels.

  Amino acids 20120601

• A convenient route to optically pure α-alkyl-β-(sec-amino)alanines.

  Amino acids 20120601

• Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells.

  Amino acids 20120601

• N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development.

  Biological psychiatry 20120601

• Combining flagelliform and dragline spider silk motifs to produce tunable synthetic biopolymer fibers.

  Biopolymers 20120601

• Effects of alanine aminotransferase inhibition on the intermediary metabolism in Sparus aurata through dietary amino-oxyacetate supplementation.

  The British journal of nutrition 20120601

• Rebamipide increases mucin-like substance contents and periodic acid Schiff reagent-positive cells density in normal rabbits.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20120601

• Highly potent antidiuretic antagonists: conformational studies of vasopressin analogues modified with 1-naphthylalanine enantiomers at position 2.

  Chemical biology & drug design 20120601

• Differential regulation of alanine aminotransferase homologues by abiotic stresses in wheat (Triticum aestivum L.) seedlings.

  Plant cell reports 20120601

• Rebamipide increases the mucin-like glycoprotein production in corneal epithelial cells.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20120601

• Stereoselective degradation of metalaxyl and its enantiomers in rat and rabbit hepatic microsomes in vitro.

  Xenobiotica; the fate of foreign compounds in biological systems 20120601

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  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120601

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  Chemosphere 20120601

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  The FEBS journal 20120601

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  Chembiochem : a European journal of chemical biology 20120529

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  Physical chemistry chemical physics : PCCP 20120528

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  Biochemistry 20120515

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  Developmental cell 20120515

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  Gene 20120510

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  Nature protocols 20120510

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  Biochemistry 20120508

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  Dalton transactions (Cambridge, England : 2003) 20120507

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  The Journal of biological chemistry 20120504

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  Amino acids 20120501

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  Bulletin of environmental contamination and toxicology 20120501

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  Gene 20120501

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  Langmuir : the ACS journal of surfaces and colloids 20120417

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  Physical chemistry chemical physics : PCCP 20120407

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  The Journal of biological chemistry 20120406

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  Journal of computational chemistry 20120405

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  The journal of physical chemistry. B 20120405

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  Langmuir : the ACS journal of surfaces and colloids 20120403

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  Journal of molecular modeling 20120401

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  Journal of the American Society for Mass Spectrometry 20120401

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  Journal of neurochemistry 20120401

• Like-charged residues at the ends of oligoalanine sequences might induce a chain reversal.

  Biopolymers 20120401

• A proximal pair of positive charges provides the dominant ligand-binding contribution to complement-like domains from the LRP (low-density lipoprotein receptor-related protein).

  The Biochemical journal 20120401

• Cochlear kainate receptors.

  Journal of the Association for Research in Otolaryngology : JARO 20120401

• Phase II, open-label study of brivanib as second-line therapy in patients with advanced hepatocellular carcinoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20120401

• Can rebamipide and proton pump inhibitor combination therapy promote the healing of endoscopic submucosal dissection-induced ulcers? A randomized, prospective, multicenter study.

  Gastrointestinal endoscopy 20120401

• NINJURIN1 single nucleotide polymorphism and nerve damage in leprosy.

  Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20120401

• Gly or Ala substitutions for Pro(210)Thr(211)Asn(212) at the β8-β9 turn of subtilisin Carlsberg increase the catalytic rate and decrease thermostability.

  Biochimica et biophysica acta 20120401

• Second-line therapies in hepatocellular carcinoma: emergence of resistance to sorafenib.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20120401

• Influence of Val16Ala SOD2 polymorphism on the in-vitro effect of clomiphene citrate in oxidative metabolism.

  Reproductive biomedicine online 20120401

• Reversible and pH-dependent weak drug-excipient binding does not affect oral bioavailability of high dose drugs.

  The Journal of pharmacy and pharmacology 20120401

• QT effect of semagacestat at therapeutic and supratherapeutic doses.

  International journal of clinical pharmacology and therapeutics 20120401

• Rebamipide attenuates nonsteroidal anti-inflammatory drugs (NSAID) induced lipid peroxidation by the manganese superoxide dismutase (MnSOD) overexpression in gastrointestinal epithelial cells.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20120401

• Identification of isomeric 5-hydroxytryptophan- and oxindolylalanine-containing peptides by mass spectrometry.

  Journal of mass spectrometry : JMS 20120401

• Toxic role of K+ channel oxidation in mammalian brain.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120321

• Method for the sequential online analysis of enzyme reactions based on capillary electrophoresis.

  Analytical chemistry 20120320

• Discovery and development of the χ-conopeptide class of analgesic peptides.

  Toxicon : official journal of the International Society on Toxinology 20120315

• Reduced expression of the μ opioid receptor in some, but not all, brain regions in mice with OPRM1 A112G.

  Neuroscience 20120315

• The conformers of 3-fluoroalanine. A theoretical study.

  Organic & biomolecular chemistry 20120314

• Effects of the selective kainate receptor antagonist ACET on altered sensorimotor gating in a genetic model of reduced NMDA receptor function.

  Brain research 20120314

• Rebamipide suppresses diclofenac-induced intestinal permeability via mitochondrial protection in mice.

  World journal of gastroenterology 20120314

• Effect of polymer containing a naphthyl-alanine derivative on the separation selectivity for aromatic compounds in temperature-responsive chromatography.

  Journal of chromatography. A 20120309

• Immobilization of chitosan in sol-gel phases for chiral open-tubular capillary electrochromatography.

  Analytica chimica acta 20120309

• Biophysical characterisation of the nucleocapsid protein from a highly pathogenic porcine reproductive and respiratory syndrome virus strain.

  Biochemical and biophysical research communications 20120309

• Relative response of alanine dosemeters for high-energy electrons determined using a Fricke primary standard.

  Physics in medicine and biology 20120307

• Influence of pine or oak wood on the degradation of alachlor and metalaxyl in soil.

  Journal of environmental management 20120301

• Population pharmacokinetic model for a novel oral hypoglycemic formed in vivo: comparing the use of active metabolite data alone versus using data of upstream and downstream metabolites.

  Journal of clinical pharmacology 20120301

• The role of Ala231 and Trp227 in the substrate specificities of fungal 17β-hydroxysteroid dehydrogenase and trihydroxynaphthalene reductase: Steroids versus smaller substrates.

  The Journal of steroid biochemistry and molecular biology 20120301

• Mutant SOD1 forms ion channel: implications for ALS pathophysiology.

  Neurobiology of disease 20120301

• Phenotypic variation within a clonal lineage of Phytophthora infestans infecting both tomato and potato in Nicaragua.

  Phytopathology 20120301

• Superoxide dismutase 2 Val16Ala polymorphism is a risk factor for the valproic acid-related elevation of serum aminotransferases.

  Epilepsy research 20120301

• Dual task abilities as a possible preclinical marker of Alzheimer's disease in carriers of the E280A presenilin-1 mutation.

  Journal of the International Neuropsychological Society : JINS 20120301

• Effect of fungicides on plant growth promoting activities of phosphate solubilizing Pseudomonasputida isolated from mustard (Brassica compestris) rhizosphere.

  Chemosphere 20120301

• Differential contribution of TM6 and TM12 to the pore of CFTR identified by three sulfonylurea-based blockers.

  Pflugers Archiv : European journal of physiology 20120301

• Enantioselective toxic effects and biodegradation of benalaxyl in Scenedesmus obliquus.

  Chemosphere 20120301

• Prediction of hot spots in protein interfaces using a random forest model with hybrid features.

  Protein engineering, design & selection : PEDS 20120301

• Effect of amino acids on red pigments and citrinin production in Monascus ruber.

  Journal of food science 20120301

• Hydrophobic residues in small ankyrin 1 participate in binding to obscurin.

  Molecular membrane biology 20120301

• Does the aromatic L-amino acid decarboxylase contribute to thyronamine biosynthesis?

  Molecular and cellular endocrinology 20120226

• High-yield cell-free protein synthesis for site-specific incorporation of unnatural amino acids at two sites.

  Biochemical and biophysical research communications 20120224

• Development and validation of a bioanalytical LC-MS method for the quantification of GHRP-6 in human plasma.

  Journal of pharmaceutical and biomedical analysis 20120223

• Amino acid tissue levels and GABAA receptor binding in the developing rat cerebellum following status epilepticus.

  Brain research 20120223

• Mitochondrial ATP synthase catalytic mechanism: a novel visual comparative structural approach emphasizes pivotal roles for Mg²⁺ and P-loop residues in making ATP.

  Biochemistry 20120221

• Fine-tuning the π-π aromatic interactions in peptides: somatostatin analogues containing mesityl alanine.

  Angewandte Chemie (International ed. in English) 20120220

• Conversion of cysteine into dehydroalanine enables access to synthetic histones bearing diverse post-translational modifications.

  Angewandte Chemie (International ed. in English) 20120220

• Facile double-functionalization of designed ankyrin repeat proteins using click and thiol chemistries.

  Bioconjugate chemistry 20120215

• Discovery of a new class of potent prolylcarboxypeptidase inhibitors derived from alanine.

  Bioorganic & medicinal chemistry letters 20120215

• Regulation of mitochondrial transport and inter-microtubule spacing by tau phosphorylation at the sites hyperphosphorylated in Alzheimer's disease.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120215

• Synthesis, characterization and application of enrofloxacin complexes as thermal stabilizers for rigid poly(vinyl chloride).

  Dalton transactions (Cambridge, England : 2003) 20120214

• Differential effects between γ-secretase inhibitors and modulators on cognitive function in amyloid precursor protein-transgenic and nontransgenic mice.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120208

• Direct affinity screening chromatography-mass spectrometry assay for identification of antibacterial agents from natural product sources.

  Analytica chimica acta 20120203

• Comparative studies on IR, Raman, and surface enhanced Raman scattering spectroscopy of dipeptides containing ΔAla and ΔPhe.

  The journal of physical chemistry. B 20120202

• Beneficial effect of pyruvate therapy on Leigh syndrome due to a novel mutation in PDH E1α gene.

  Brain & development 20120201

• Noncovalent and covalent functionalization of a (5, 0) single-walled carbon nanotube with alanine and alanine radicals.

  Journal of molecular modeling 20120201

• Metabolic modulation induced by oestradiol and DHT in immature rat Sertoli cells cultured in vitro.

  Bioscience reports 20120201

• Analysis of vibrational spectra and nonlinear optical properties of organic molecule L-alaninium formate.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120201

• Growth, spectroscopic, dielectric and nonlinear optical studies of semi organic nonlinear optical crystal--L-alanine lithium chloride.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120201

• Alanine racemase mutants of Mycobacterium tuberculosis require D-alanine for growth and are defective for survival in macrophages and mice.

  Microbiology (Reading, England) 20120201

• Cell-selective labeling of bacterial proteomes with an orthogonal phenylalanine amino acid reporter.

  Chemical communications (Cambridge, England) 20120201

• Estimation of the rotamerization constants of different conformations of N-acetylalanine: a theoretical and matrix-isolation FT-IR study.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120201

• Testing a portable Raman instrument: the detection of biomarkers in gypsum powdered matrix under gypsum crystals.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120201

• Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses.

  Nature neuroscience 20120201

• Metabolomic biomarkers of impaired glucose tolerance and type 2 diabetes mellitus with a potential for risk stratification in women with polycystic ovary syndrome.

  European journal of obstetrics, gynecology, and reproductive biology 20120201

• Are thrombophilia more multifactorial than we thought: report of mosaicism for FII G20210A and novel FII T20061C gene variants.

  Journal of thrombosis and haemostasis : JTH 20120201

• Effect of insulin deprivation on metabolism and metabolism-associated gene transcript levels of in vitro cultured human Sertoli cells.

  Biochimica et biophysica acta 20120201

• Oligomerization of glycine and alanine catalyzed by iron oxides: implications for prebiotic chemistry.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20120201

• Structural consensus among antibodies defines the antigen binding site.

  PLoS computational biology 20120201

• [UV spectroscopy coupled with partial least squares to determine the enantiomeric composition in chiral drugs].

  Guang pu xue yu guang pu fen xi = Guang pu 20120201

• Generalized essential energy space random walks to more effectively accelerate solute sampling in aqueous environment.

  The Journal of chemical physics 20120128

• Two different packing arrangements of antiparallel polyalanine.

  Angewandte Chemie (International ed. in English) 20120127

• Conformation-dependent ˙OH/H2O2 hydrogen abstraction reaction cycles of Gly and Ala residues: a comparative theoretical study.

  The journal of physical chemistry. B 20120126

• Accessing structure and dynamics of mobile phase in organic solids by real-time T1C filter PISEMA NMR spectroscopy.

  The journal of physical chemistry. A 20120126

• Active site substitution A82W improves the regioselectivity of steroid hydroxylation by cytochrome P450 BM3 mutants as rationalized by spin relaxation nuclear magnetic resonance studies.

  Biochemistry 20120124

• Dominant-negative control of cAMP-dependent IKs upregulation in human long-QT syndrome type 1.

  Circulation research 20120120

• A site-directed mutagenesis method particularly useful for creating otherwise difficult-to-make mutants and alanine scanning.

  Analytical biochemistry 20120115

• Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline.

  Free radical biology & medicine 20120115

• Structural basis for recognition of H3T3ph and Smac/DIABLO N-terminal peptides by human Survivin.

  Structure (London, England : 1993) 20120111

• Alanine scanning of all cysteines and construction of a functional cysteine-less Cdr1p, a multidrug ABC transporter of Candida albicans.

  Biochemical and biophysical research communications 20120106

• A biomimetic approach to lanthionines.

  Organic letters 20120106

• An in vitro model of glucose and lipid metabolism in a multicompartmental bioreactor.

  Biotechnology journal 20120101

• Effects of pyruvate dose on in vivo metabolism and quantification of hyperpolarized ¹³C spectra.

  NMR in biomedicine 20120101

• Contributing factors to gastric ulcer healing after endoscopic submucosal dissection including the promoting effect of rebamipide.

  Digestive diseases and sciences 20120101

• A randomized, double-blind, placebo-controlled trial of safinamide as add-on therapy in early Parkinson's disease patients.

  Movement disorders : official journal of the Movement Disorder Society 20120101

• Genetic diversity of Phytophthora capsici isolates from pepper and pumpkin in Argentina.

  Mycologia 20120101

• Caveolin-1 hydrophobic segment peptides insertion into membrane mimetic systems: role of proline residue.

  Biochimica et biophysica acta 20120101

• The application of an alanine-substituted mutant of the C-terminal fragment of Clostridium perfringens enterotoxin as a mucosal vaccine in mice.

  Biomaterials 20120101

• Synthesis of analogues of ochratoxin A.

  Natural product research 20120101

• Identification of the oxidative and conjugative enzymes involved in the biotransformation of brivanib.

  Drug metabolism and disposition: the biological fate of chemicals 20120101

• Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G.

  Journal of leukocyte biology 20120101

• Enzymatic properties of the glycine D-alanine [corrected] aminopeptidase of Aspergillus oryzae and its activity profiles in liquid-cultured mycelia and solid-state rice culture (rice koji).

  Applied microbiology and biotechnology 20120101

• Conformation specificity and arene binding in a peptide composed only of Lys, Ile, Ala and Gly.

  European biophysics journal : EBJ 20120101

• Enhancement of the inhibitory effect of an IL-15 antagonist peptide by alanine scanning.

  Journal of peptide science : an official publication of the European Peptide Society 20120101

• The structure and assembly model of the third transmembrane domain of Slc11a1 in SDS micelles revealed by NMR study of the Leu-substituted peptide.

  Journal of peptide science : an official publication of the European Peptide Society 20120101

• A canine model to evaluate efficacy and safety of γ-secretase inhibitors and modulators.

  Journal of Alzheimer's disease : JAD 20120101

• A universal HPLC-MS method to determine the stereochemistry of common and unusual amino acids.

  Methods in molecular biology (Clifton, N.J.) 20120101

• The ATP-sensitive K(+) channel ABCC8 S1369A type 2 diabetes risk variant increases MgATPase activity.

  Diabetes 20120101

• Effect of P to A mutation of the N-terminal residue adjacent to the Rgd motif on rhodostomin: importance of dynamics in integrin recognition.

  PloS one 20120101

• Cdc5-dependent asymmetric localization of bfa1 fine-tunes timely mitotic exit.

  PLoS genetics 20120101

• Site-directed mutations and the polymorphic variant Ala160Thr in the human thromboxane receptor uncover a structural role for transmembrane helix 4.

  PloS one 20120101

• Functional characterization of MODY2 mutations highlights the importance of the fine-tuning of glucokinase and its role in glucose sensing.

  PloS one 20120101

• Suppressive regulation of KSHV RTA with O-GlcNAcylation.

  Journal of biomedical science 20120101

• Evaluation of the performance of novel Aβ isoforms as theragnostic markers in Alzheimer's disease: from the cell to the patient.

  Neuro-degenerative diseases 20120101

• Photostability of Iiovaline and its precursor 5-Ethyl-5- methylhydantoin exposed to simulated space radiations.

  International journal of molecular sciences 20120101

• Effect of D-alanine in teichoic acid from the Streptococcus thermophilus cell wall on the barrier-protection of intestinal epithelial cells.

  Bioscience, biotechnology, and biochemistry 20120101

• Assessment of real-time myocardial uptake and enzymatic conversion of hyperpolarized [1-¹³C]pyruvate in pigs using slice selective magnetic resonance spectroscopy.

  Contrast media & molecular imaging 20120101

• Effect of Acinetobacter sp on metalaxyl degradation and metabolite profile of potato seedlings (Solanum tuberosum L.) alpha variety.

  PloS one 20120101

• Genetic reporter system for positioning of proteins at the bacterial pole.

  mBio 20120101

• Role of the gerA operon in L-alanine germination of Bacillus licheniformis spores.

  BMC microbiology 20120101

• Toxicity of metalaxyl, azoxystrobin, dimethomorph, cymoxanil, zoxamide and mancozeb to Phytophthora infestans isolates from Serbia.

  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20120101

• Advances in the identification of γ-secretase inhibitors for the treatment of Alzheimer's disease.

  Expert opinion on drug discovery 20120101

• Modulation of γ-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's disease.

  PloS one 20120101

• Detection and characterization of a thermophilic biotin biosynthetic enzyme, 7-keto-8-aminopelargonic acid synthase, from various thermophiles.

  Bioscience, biotechnology, and biochemistry 20120101

• Role of tryptophan residues in a class V chitinase from Nicotiana tabacum.

  Bioscience, biotechnology, and biochemistry 20120101

• Molecular modeling of the M3 acetylcholine muscarinic receptor and its binding site.

  Journal of biomedicine & biotechnology 20120101

• Evaluation of systemic redox states in patients carrying the MELAS A3243G mutation in mitochondrial DNA.

  European neurology 20120101

• Persistence of metalaxyl and mancozeb on potato leaves and their residues in tubers.

  Pakistan journal of biological sciences : PJBS 20120101

• Amyloid-β(1-15/16) as a marker for γ-secretase inhibition in Alzheimer's disease.

  Journal of Alzheimer's disease : JAD 20120101

• Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1.

  PloS one 20120101

• An optical overview of poly[μ(2)-L-alanine-μ(3)-nitrato-sodium(I)] crystals.

  TheScientificWorldJournal 20120101

• [The study of molecular mechanisms of action of natural amino acids and serotonin on adenylyl and guanylyl cyclases of the ciliates].

  Tsitologiia 20120101

• Effect of L-arginine supplement on liver regeneration after partial hepatectomy in rats.

  World journal of surgical oncology 20120101

• Identification of Sare0718 as an alanine-activating adenylation domain in marine actinomycete Salinispora arenicola CNS-205.

  PloS one 20120101

• Phosphatidylcholine formation by LPCAT1 is regulated by Ca(2+) and the redox status of the cell.

  BMC biochemistry 20120101

• The extracellular subunit interface of the 5-HT3 receptors: a computational alanine scanning mutagenesis study.

  Journal of biomolecular structure & dynamics 20120101

• γ-Secretase modulator in Alzheimer's disease: shifting the end.

  Journal of Alzheimer's disease : JAD 20120101

• Enhancing the affinity of SEB-binding peptides by repeating their sequence.

  Biopolymers 20120101

• Monitoring structural transitions in IDPs by vibrational spectroscopy of cyanylated cysteine.

  Methods in molecular biology (Clifton, N.J.) 20120101

• A single residue determines the cooperative binding property of a primosomal DNA replication protein, PriB, to single-stranded DNA.

  Bioscience, biotechnology, and biochemistry 20120101

• Role of the myristoylation site in expressing exogenous functional proteins in coxsackieviral vector.

  Bioscience, biotechnology, and biochemistry 20120101

• Protein N-myristoylation is required for cellular morphological changes induced by two formin family proteins, FMNL2 and FMNL3.

  Bioscience, biotechnology, and biochemistry 20120101

• pPKCα-mediated effect on in vitro Aβ production in response to gamma secretase inhibitor LY411575 in rat CTXTNA2 astrocytes.

  Journal of biological regulators and homeostatic agents 20120101

• 6-Arylpyrido[2,3-d]pyrimidines as novel ATP-competitive inhibitors of bacterial D-alanine:D-alanine ligase.

  PloS one 20120101

• Terminal-restriction fragment length polymorphism (T-RFLP) analysis for changes in the gut microbiota profiles of indomethacin- and rebamipide-treated mice.

  Digestion 20120101

• Paralogous ALT1 and ALT2 retention and diversification have generated catalytically active and inactive aminotransferases in Saccharomyces cerevisiae.

  PloS one 20120101

• Conjugation of proteins by installing BIO-orthogonally reactive groups at their N-termini.

  PloS one 20120101

• Amino acid substitutions of MagA in Klebsiella pneumoniae affect the biosynthesis of the capsular polysaccharide.

  PloS one 20120101

• Detection of farnesyltransferase interface hot spots through computational alanine scanning mutagenesis.

  The journal of physical chemistry. B 20111229

• Using infrared spectroscopy of cyanylated cysteine to map the membrane binding structure and orientation of the hybrid antimicrobial peptide CM15.

  Biochemistry 20111227

• Osteogenesis imperfecta missense mutations in collagen: structural consequences of a glycine to alanine replacement at a highly charged site.

  Biochemistry 20111220

• Actions of juglone on energy metabolism in the rat liver.

  Toxicology and applied pharmacology 20111215

• Host-guest chemistry in the gas phase: complex formation with 18-crown-6 enhances helicity of alanine-based peptides.

  The journal of physical chemistry. A 20111215

• Aspirin-induced small bowel injuries and the preventive effect of rebamipide.

  World journal of gastroenterology 20111214

• The steroid interaction site in transmembrane domain 2 of the large conductance, voltage- and calcium-gated potassium (BK) channel accessory β1 subunit.

  Proceedings of the National Academy of Sciences of the United States of America 20111213

• Transdermal and transbuccal drug delivery systems: enhancement using iontophoretic and chemical approaches.

  International journal of pharmaceutics 20111212

• Enzymatically degradable mussel-inspired adhesive hydrogel.

  Biomacromolecules 20111212

• γ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1.

  The Journal of biological chemistry 20111209

• Structure-activity relationship of T-cell receptors based on alanine scanning.

  Biochemical and biophysical research communications 20111202

• Lack of food effect on single-dose pharmacokinetics of brivanib, and safety and efficacy following multiple doses in subjects with advanced or metastatic solid tumors.

  Cancer chemotherapy and pharmacology 20111201

• 13C high-resolution-magic angle spinning MRS reveals differences in glucose metabolism between two breast cancer xenograft models with different gene expression patterns.

  NMR in biomedicine 20111201

• The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport.

  British journal of pharmacology 20111201

• L-cysteine-enhanced renaturation of bioactive soluble tumor necrosis factor ligand family member LIGHT from inclusion bodies in Escherichia coli.

  Protein expression and purification 20111201

• Sensitivity of alanine dosimeters with gadolinium exposed to 6 MV photons at clinical doses.

  Radiation research 20111201

• Pressor response to oral tyramine during co-administration with safinamide in healthy volunteers.

  Naunyn-Schmiedeberg's archives of pharmacology 20111201

• Randomized tree construction algorithm to explore energy landscapes.

  Journal of computational chemistry 20111201

• Severe dysfunction of respiratory chain and cholesterol metabolism in Atp7b(-/-) mice as a model for Wilson disease.

  Biochimica et biophysica acta 20111201

• Investigation of biomolecules trapped in fluid inclusions inside halite crystals by Raman spectroscopy.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111201

• Quantitative pharmacokinetic/pharmacodynamic analyses suggest that the 129/SVE mouse is a suitable preclinical pharmacology model for identifying small-molecule γ-secretase inhibitors.

  The Journal of pharmacology and experimental therapeutics 20111201

• The phosphorylation status of the chloroplast protein kinase STN7 of Arabidopsis affects its turnover.

  Plant physiology 20111201

• Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1.

  The Journal of clinical investigation 20111201

• Formulation of solid dispersion of rebamipide evaluated in a rat model for improved bioavailability and efficacy.

  The Journal of pharmacy and pharmacology 20111201

• PGC-1α protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model.

  Muscle & nerve 20111201

• Rotational-echo double-resonance NMR. 1989.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20111201

• [The effects of Rebamipide and Polaprezinc mouthwash and uptake on mucositis induced by chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20111201

• Preliminary studies on the effect of rebamipide against the trypsin and egg-albumin induced experimental model of asthma.

  Acta pharmaceutica (Zagreb, Croatia) 20111201

• [Gamma-secretase inhibitors and modulators].

  Nihon rinsho. Japanese journal of clinical medicine 20111201

• A8344G mutation of the mitochondrial DNA with typical mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome.

  Ideggyogyaszati szemle 20111130

• Revisitation of the βCl-elimination reaction of D-amino acid oxidase: new interpretation of the reaction that sparked flavoprotein dehydrogenation mechanisms.

  The Journal of biological chemistry 20111125

• (S)-Styryl-α-alanine used to probe the intermolecular mechanism of an intramolecular MIO-aminomutase.

  Biochemistry 20111122

• Study on the conformational equilibrium of the alanine dipeptide in water solution by using the averaged solvent electrostatic potential from molecular dynamics methodology.

  The Journal of chemical physics 20111121

• Random-coil:α-helix equilibria as a reporter for the Lewis(X)-Lewis(X) interaction.

  Angewandte Chemie (International ed. in English) 20111118

• Specific interactions of sodium salts with alanine dipeptide and tetrapeptide in water: insights from molecular dynamics.

  The journal of physical chemistry. B 20111117

• Dopamine-depletion and increased α-synuclein load induce degeneration of cortical cholinergic fibers in mice.

  Journal of the neurological sciences 20111115

• Allosteric interaction of nucleotides and tRNA(ala) with E. coli alanyl-tRNA synthetase.

  Biochemistry 20111115

• Solid-phase synthesis of smac peptidomimetics incorporating triazoloprolines and biarylalanines.

  ACS combinatorial science 20111114

• Isotope labeling studies on the formation of multiple addition products of alanine in the pyrolysis residue of glucose/alanine mixtures by high-resolution ESI-TOF-MS.

  Journal of agricultural and food chemistry 20111109

• Hippocampal GluA1-containing AMPA receptors mediate context-dependent sensitization to morphine.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20111109

• Structure of a monomeric mutant of the HIV-1 capsid protein.

  Biochemistry 20111108

• Simultaneous two-dimensional HPLC determination of free D-serine and D-alanine in the brain and periphery of mutant rats lacking D-amino-acid oxidase.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101

• Chemical form of selenium affects its uptake, transport, and glutathione peroxidase activity in the human intestinal Caco-2 cell model.

  Biological trace element research 20111101

• HPLC determination of the distribution of D-amino acids and effects of ecdysis on alanine racemase activity in kuruma prawn Marsupenaeus japonicus.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101

• Use of Marfey's reagent and analogs for chiral amino acid analysis: assessment and applications to natural products and biological systems.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101

• Two cases of oculopharyngeal muscular dystrophy (OPMD) with the rare PABPN1 c.35G>C; p.Gly12Ala point mutation.

  Neuromuscular disorders : NMD 20111101

• Characterization of d-boroAla as a novel broad-spectrum antibacterial agent targeting d-Ala-d-Ala ligase.

  Chemical biology & drug design 20111101

• A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes.

  Human molecular genetics 20111101

• Synthesis, structural characterization and antimicrobial activity evaluation of metal complexes of sparfloxacin.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111101

• Highly conserved tyrosine 37 stabilizes desensitized states and restricts calcium permeability of ATP-gated P2X3 receptor.

  Journal of neurochemistry 20111101

• Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin.

  Nature structural & molecular biology 20111101

• Binding and selectivity of the marine toxin neodysiherbaine A and its synthetic analogues to GluK1 and GluK2 kainate receptors.

  Journal of molecular biology 20111028

• Directed evolution of a gatekeeper domain in nonribosomal peptide synthesis.

  Chemistry & biology 20111028

• Reversible hydrogen transfer reactions of cysteine thiyl radicals in peptides: the conversion of cysteine into dehydroalanine and alanine, and of alanine into dehydroalanine.

  The journal of physical chemistry. B 20111027

• The challenge of the lantibiotics: synthetic approaches to thioether-bridged peptides.

  Organic & biomolecular chemistry 20111026

• Adaptations to in situ feeding: novel nutrient acquisition pathways in an ancient vertebrate.

  Proceedings. Biological sciences 20111022

• Synthesis of an NDPK phosphocarrier domain peptide containing a novel triazolylalanine analogue of phosphohistidine using click chemistry.

  Organic letters 20111021

• Experimental determination of the energy response of alanine pellets in the high dose rate 192Ir spectrum.

  Physics in medicine and biology 20111021

• Control of carbon nanotube handedness using a supramolecular chiral surface.

  The Journal of chemical physics 20111021

• Effects of the Ala379Val polymorphism of lipoprotein-associated phospholipase A2 on thrombosis and inflammation in hypertensive patients.

  International journal of cardiology 20111020

• Variations in protein-flavin hydrogen bonding in a light, oxygen, voltage domain produce non-Arrhenius kinetics of adduct decay.

  Biochemistry 20111018

• Growth, structural, spectral, mechanical, thermal and dielectric characterization of phosphoric acid admixtured L-alanine (PLA) single crystals.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111015

• Single crystal nuclear magnetic resonance in spinning powders.

  The Journal of chemical physics 20111014

• Structural insight into the Mycobacterium tuberculosis Rv0020c protein and its interaction with the PknB kinase.

  Structure (London, England : 1993) 20111012

• Probing the structural and energetic basis of kinesin-microtubule binding using computational alanine-scanning mutagenesis.

  Biochemistry 20111011

• Different clinical and neuropathologic phenotypes of familial ALS with A315E TARDBP mutation.

  Neurology 20111011

• Selective enzymatic degradation of self-assembled particles from amphiphilic block copolymers obtained by the combination of N-carboxyanhydride and nitroxide-mediated polymerization.

  Biomacromolecules 20111010

• Substrate tRNA recognition mechanism of a multisite-specific tRNA methyltransferase, Aquifex aeolicus Trm1, based on the X-ray crystal structure.

  The Journal of biological chemistry 20111007

• A single active-site mutation of P450BM-3 dramatically enhances substrate binding and rate of product formation.

  Biochemistry 20111004

• An autolytic process for recovery of antioxidant activity rich carotenoprotein from shrimp heads.

  Marine biotechnology (New York, N.Y.) 20111001

• Sequence analysis of PAX9, MSX1 and AXIN2 genes in a Chinese oligodontia family.

  Archives of oral biology 20111001

• Three novel CYP17A1 gene mutations (A82D, R125X, and C442R) found in combined 17α-hydroxylase/17,20-lyase deficiency.

  Metabolism: clinical and experimental 20111001

• Frequency of uridine monophosphate synthase Gly(213)Ala polymorphism in Caucasian gastrointestinal cancer patients and healthy subjects, investigated by means of new, rapid genotyping assays.

  Genetic testing and molecular biomarkers 20111001

• Pro12Ala polymorphism in human peroxisome proliferator activated receptor gamma is associated with hyperlipidaemia in obstructive sleep apnoea hypopnoea syndrome.

  The Journal of laryngology and otology 20111001

• Residues 248-252 and 300-304 of the cardiac Na+/Ca2+ exchanger are involved in its regulation by phospholemman.

  American journal of physiology. Cell physiology 20111001

• Solanum nigrum L. weed plants as a remediation tool for metalaxyl-polluted effluents and soils.

  Chemosphere 20111001

• First-trimester prediction of preeclampsia using metabolomic biomarkers: a discovery phase study.

  Prenatal diagnosis 20111001

• Role of the C-terminal domain of PCSK9 in degradation of the LDL receptors.

  Journal of lipid research 20111001

• Influence of substituents on the nitrogen atom of 3-[2-(4-aminophenyl)benzoxazol-5-yl]alanine derivatives on their photophysical properties--solvatochromic studies.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111001

• Identification of octopine dehydrogenase from Mytilus galloprovincialis.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20111001

• Genome-enabled determination of amino acid biosynthesis in Xanthomonas campestris pv. campestris and identification of biosynthetic pathways for alanine, glycine, and isoleucine by 13C-isotopologue profiling.

  Molecular genetics and genomics : MGG 20111001

• In vivo measurement of normal rat intracellular pyruvate and lactate levels after injection of hyperpolarized [1-(13)C]alanine.

  Magnetic resonance imaging 20111001

• Site-specific ϕ- and ψ-torsion angle determination in a uniformly/extensively 13C- and 15N-labeled peptide.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20111001

• Malignant peripheral nerve sheath tumour presenting as a pneumothorax.

  The British journal of radiology 20111001

• Combining modelling and mutagenesis studies of synaptic vesicle protein 2A to identify a series of residues involved in racetam binding.

  Biochemical Society transactions 20111001

• Stability of amino acids and their oligomerization under high-pressure conditions: implications for prebiotic chemistry.

  Astrobiology 20111001

• Metabolic changes during a field experiment in a world-class windsurfing athlete: a trial with multivariate analyses.

  Omics : a journal of integrative biology 20111001

• [Investigation of how to prevent mucositis induced by chemoradiotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20111001

• Association of serum lipid/lipoprotein with Pro12Ala polymorphism in PPAR-γ2 among Chinese nonagenarians/centenarians.

  Archives of medical research 20111001

• Mass spectrometric characterization of peptides containing different oxidized tryptophan residues.

  Journal of mass spectrometry : JMS 20111001

• The critical main-chain length for helix formation in water: determined in a peptide series with alternating Aib and Ala residues exclusively and detected with ECD spectroscopy.

  Chirality 20111001

• [Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].

  Guang pu xue yu guang pu fen xi = Guang pu 20111001

• Analgesic tolerance to high-efficacy agonists but not to morphine is diminished in phosphorylation-deficient S375A μ-opioid receptor knock-in mice.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20110928

• Low energy (0-10 eV) electron driven reactions in the halogenated organic acids CCl3COOH, CClF2COOH, and CF3CHNH2COOH (trifluoroalanine).

  The Journal of chemical physics 20110928

• A 'tag-and-modify' approach to site-selective protein modification.

  Accounts of chemical research 20110920

• Metabolic flux analysis gives an insight on verapamil induced changes in central metabolism of HL-1 cells.

  Journal of biotechnology 20110920

• Formation of dehydroalanine from mimosine and cysteine: artifacts in gas chromatography/mass spectrometry based metabolomics.

  Rapid communications in mass spectrometry : RCM 20110915

• Temperature dependences of piezoelectric, elastic and dielectric constants of L-alanine crystal.

  Journal of physics. Condensed matter : an Institute of Physics journal 20110907

• Rebamipide promotes healing of colonic ulceration through enhanced epithelial restitution.

  World journal of gastroenterology 20110907

• Response of GWALP transmembrane peptides to changes in the tryptophan anchor positions.

  Biochemistry 20110906

• Unexpected opioid activity profiles of analogues of the novel peptide kappa opioid receptor ligand CJ-15,208.

  ChemMedChem 20110905

• Occludin localizes to centrosomes and modifies mitotic entry.

  The Journal of biological chemistry 20110902

• The auto-ubiquitylation of E3 ubiquitin-protein ligase Chfr at G2 phase is required for accumulation of polo-like kinase 1 and mitotic entry in mammalian cells.

  The Journal of biological chemistry 20110902

• Comparison of post-mortem metabolic changes in sheep brain tissue in isolated heads and whole animals using 1H-MR spectroscopy--preliminary results.

  International journal of legal medicine 20110901

• Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons.

  Neurochemistry international 20110901

• Investigating the genetic structure of Phytophthora capsici populations.

  Phytopathology 20110901

• Ruminococcin C, a new anti-Clostridium perfringens bacteriocin produced in the gut by the commensal bacterium Ruminococcus gnavus E1.

  Biochimie 20110901

• Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice model.

  Neurobiology of disease 20110901

• Hind limb muscle atrophy precedes cerebral neuronal degeneration in G93A-SOD1 mouse model of amyotrophic lateral sclerosis: a longitudinal MRI study.

  Experimental neurology 20110901

• Q8IYL2 is a candidate gene for the familial epilepsy syndrome of Partial Epilepsy with Pericentral Spikes (PEPS).

  Epilepsy research 20110901

• A Single phenylalanine residue in the main intracellular loop of α1 γ-aminobutyric acid type A and glycine receptors influences their sensitivity to propofol.

  Anesthesiology 20110901

• Electrostatic exploration of the C3d-FH4 interaction using a computational alanine scan.

  Molecular immunology 20110901

• Growth, structural, vibrational, optical, laser and dielectric aspects of L-alanine alaninium nitrate single crystal.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901

• Molecular dynamics study of small molecule inhibitors of the Bcl-2 family.

  Proteins 20110901

• Role of the omega loop in specificity determination in subsite 2 of the D-alanine:D-alanine (D-lactate) ligase from Leuconostoc mesenteroides: a molecular docking study.

  Journal of molecular graphics & modelling 20110901

• Investigating the effect of a single glycine to alanine substitution on interactions of antimicrobial peptide latarcin 2a with a lipid membrane.

  European biophysics journal : EBJ 20110901

• Glutamine and α-ketoglutarate as glutamate sources for glutathione synthesis in human erythrocytes.

  The FEBS journal 20110901

• Structural effects of N-aromatic acyl-amino acid conjugates on their deconjugation in the cecal contents of rats: implication in design of a colon-specific prodrug with controlled conversion rate at the target site.

  Biopharmaceutics & drug disposition 20110901

• Functionalized polystyrene supports for solid-phase synthesis of glycyl-, alanyl-, and isoleucyl-RNA conjugates as hydrolysis-resistant mimics of peptidyl-tRNAs.

  Bioorganic & medicinal chemistry 20110901

• Ellipticines and 9-acridinylamines as inhibitors of D-alanine:D-alanine ligase.

  Bioorganic & medicinal chemistry 20110901

• Effects of alkyl side chains on properties of aliphatic amino acids probed using quantum chemical calculations.

  Journal of synchrotron radiation 20110901

• Fragmentation characteristics of b(n) (n=2-15) ions from protonated peptides.

  Rapid communications in mass spectrometry : RCM 20110830

• Temperature-dependent intensity anomalies in amino acid esters: weak hydrogen bonds in protected glycine, alanine and valine.

  Physical chemistry chemical physics : PCCP 20110821

• Substrate specificity of the aspartate:alanine antiporter (AspT) of Tetragenococcus halophilus in reconstituted liposomes.

  The Journal of biological chemistry 20110819

• Synthesis of peptides containing overlapping lanthionine bridges on the solid phase: an analogue of rings D and E of the lantibiotic nisin.

  Organic letters 20110819

• The influence of the stereochemistry of alanine residue on the solid state conformation and crystal packing of opioid peptides containing D-Ala or L-Ala in message domain--XRD and NMR study.

  The journal of physical chemistry. B 20110818

• Conformational changes of trialanine induced by direct interactions between alanine residues and alcohols in binary mixtures of water with glycerol and ethanol.

  Journal of the American Chemical Society 20110817

• Crystal and molecular structure of N-(4-nitrophenyl)-β-alanine--its vibrational spectra and theoretical calculations.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110815

• Clinical, electrophysiological and pathological findings of a patient with CMT2 due to the p.Ala738Val mitofusin 2 mutation.

  Journal of the neurological sciences 20110815

• Brivanib, a dual FGF/VEGF inhibitor, is active both first and second line against mouse pancreatic neuroendocrine tumors developing adaptive/evasive resistance to VEGF inhibition.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110815

• Overcoming antiangiogenic resistance.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110815

• DFT characterization of key intermediates in thiols oxidation catalyzed by amavadin.

  Dalton transactions (Cambridge, England : 2003) 20110814

• Different roles of the two components of human protein O-mannosyltransferase, POMT1 and POMT2.

  Biochemical and biophysical research communications 20110812

• Exploring and characterizing the folding processes of Lys- and Arg-containing Ala-based peptides: a molecular dynamics study.

  Computational biology and chemistry 20110810

• Identification and physicochemical characterization of BldR2 from Sulfolobus solfataricus, a novel archaeal member of the MarR transcription factor family.

  Biochemistry 20110809

• A short and efficient synthesis of neodysiherbaine A by using catalytic oxidative cyclization.

  Angewandte Chemie (International ed. in English) 20110808

• Synthesis of alanine-based colorimetric sensors and enantioselective recognition of aspartate and malate anions.

  Organic & biomolecular chemistry 20110807

• A study of mass transfer kinetics of alanyl-alanine on a chiral crown ether stationary phase.

  Journal of chromatography. A 20110805

• Structure and mechanism of the trans-acting acyltransferase from the disorazole synthase.

  Biochemistry 20110802

• Metabolic profiles in serum of mouse after chronic exposure to drinking water.

  Human & experimental toxicology 20110801

• Investigation of interferon-α response by a single amino acid substitution of nonstructural protein 5A in hepatitis C virus-infected patients.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20110801

• Characterisation of L-alanine and glycine absorption across the gut of an ancient vertebrate.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20110801

• Biochemical characterization of evasion from peptidoglycan recognition by Staphylococcus aureus D-alanylated wall teichoic acid in insect innate immunity.

  Developmental and comparative immunology 20110801

• Quantum yields of decomposition and homo-dimerization of solid L-alanine induced by 7.2 eV Vacuum ultraviolet light irradiation: an estimate of the half-life of L-alanine on the surface of space objects.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20110801

• Alanine substitutions within a linker region of the influenza A virus non-structural protein 1 alter its subcellular localization and attenuate virus replication.

  The Journal of general virology 20110801

• Anxiolytic-like activity of pregabalin in the Vogel conflict test in α2δ-1 (R217A) and α2δ-2 (R279A) mouse mutants.

  The Journal of pharmacology and experimental therapeutics 20110801

• Multi-band frequency encoding method for metabolic imaging with hyperpolarized [1-(13)C]pyruvate.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20110801

• Regulation of D-alanylation of lipoteichoic acid in Streptococcus gordonii.

  Microbiology (Reading, England) 20110801

• Time-dependent changes in the plasma amino acid concentration in diabetes mellitus.

  Molecular genetics and metabolism 20110801

• Broadening the phenotype of TARDBP mutations: the TARDBP Ala382Thr mutation and Parkinson's disease in Sardinia.

  Neurogenetics 20110801

• Genetically encoding unnatural amino acids in neural stem cells and optically reporting voltage-sensitive domain changes in differentiated neurons.

  Stem cells (Dayton, Ohio) 20110801

• Experimental aspects in acquisition of wide bandwidth solid-state MAS NMR spectra of low-γ nuclei with different opportunities on two commercial NMR spectrometers.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20110801

• Azepanone-based inhibitors of human cathepsin S: optimization of selectivity via the P2 substituent.

  Bioorganic & medicinal chemistry letters 20110801

• Dose determination using alanine detectors in a mixed neutron and gamma field for boron neutron capture therapy of liver malignancies.

  Acta oncologica (Stockholm, Sweden) 20110801

• [Field resistance of Phytophthora melonis to metalaxyl in South China].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20110801

• Chiral separation of metalaxyl and benalaxyl fungicides by electrokinetic chromatography and determination of enantiomeric impurities.

  Journal of chromatography. A 20110729

• Monitoring selected hydrogen bonds in crystal hydrates of amino acid salts: combining variable-temperature single-crystal X-ray diffraction and polarized Raman spectroscopy.

  Physical chemistry chemical physics : PCCP 20110728

• Structure and assembly mechanism for heteromeric kainate receptors.

  Neuron 20110728

• Analytic energy gradient for second-order Møller-Plesset perturbation theory based on the fragment molecular orbital method.

  The Journal of chemical physics 20110728

• A new perspective on transition states: χ1 separatrix.

  The Journal of chemical physics 20110728

• Defining the role of the tension sensor in the mechanosensitive channel of small conductance.

  Biophysical journal 20110720

• A switch I mutant of Cdc42 exhibits less conformational freedom.

  Biochemistry 20110719

• A novel codon4 mutation (A4F) in the SOD1gene in familial amyotrophic lateral sclerosis.

  Journal of the neurological sciences 20110715

• Screening of protein-protein interaction modulators via sulfo-click kinetic target-guided synthesis.

  ACS chemical biology 20110715

• A reproducible and high-throughput HPLC/MS method to separate sarcosine from α- and β-alanine and to quantify sarcosine in human serum and urine.

  Analytical chemistry 20110715

• Adsorption and desorption behavior of metalaxyl in intensively cultivated acid soils.

  Journal of agricultural and food chemistry 20110713

• Drugs: a tangled web of targets.

  Nature 20110713

• Effect of the chirality of residues and γ-turns on the electronic excitation spectra, excited-state reaction paths and conical intersections of capped phenylalanine-alanine dipeptides.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20110711

• Three-dimensional mapping of microenvironmental control of methyl rotational barriers.

  The journal of physical chemistry. B 20110707

• 13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression.

  Cell metabolism 20110706

• Successful management of gastrointestinal pythiosis in a dog using itraconazole, terbinafine, and mefenoxam.

  Medical mycology 20110701

• Role of complement factor H I62V and age-related maculopathy susceptibility 2 A69S variants in the clinical expression of polypoidal choroidal vasculopathy.

  Ophthalmology 20110701

• Knockout of SOD1 promotes conversion of selenocysteine to dehydroalanine in murine hepatic GPX1 protein.

  Free radical biology & medicine 20110701

• Viral envelope protein folding and membrane hemifusion are enhanced by the conserved loop region of HIV-1 gp41.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110701

• Application of L-proline derivatives as chiral shift reagents for enantiomeric recognition of carboxylic acids.

  Chirality 20110701

• Alanine 32 in PilA is important for PilA stability and type IV pili function in Myxococcus xanthus.

  Microbiology (Reading, England) 20110701

• The role of Cys271 in conformational changes of arginine kinase.

  International journal of biological macromolecules 20110701

• Impact of site-specific N-glycosylation on cellular secretion, activity and specific activity of the plasma phospholipid transfer protein.

  Biochimica et biophysica acta 20110701

• Conformational, receptor interaction and alanine scan studies of glucose-dependent insulinotropic polypeptide.

  Biochimica et biophysica acta 20110701

• 1H assisted 13C/15N heteronuclear correlation spectroscopy in oriented sample solid-state NMR of single crystal and magnetically aligned samples.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20110701

• Reversible and irreversible protein glutathionylation: biological and clinical aspects.

  Expert opinion on drug metabolism & toxicology 20110701

• Silver nanoparticles disrupt olfaction in Crucian carp (Carassius carassius) and Eurasian perch (Perca fluviatilis).

  Aquatic toxicology (Amsterdam, Netherlands) 20110701

• Functional mapping of factor VIII C2 domain.

  Thrombosis and haemostasis 20110701

• Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir.

  Bioorganic & medicinal chemistry letters 20110701

• Evidence of a structural defect in Ice VII and the side-chain-dependent response of small model peptides to increased pressure.

  Applied spectroscopy 20110701

• [Pilot study on clinical effects of rebamipide gargle against oral mucositis induced by fluoropyrimidines].

  Gan to kagaku ryoho. Cancer & chemotherapy 20110701

• Prevalence of asymptomatic vasogenic edema in pretreatment Alzheimer's disease study cohorts from phase 3 trials of semagacestat and solanezumab.

  Alzheimer's & dementia : the journal of the Alzheimer's Association 20110701

• Domain motion of individual F1-ATPase β-subunits during unbiased molecular dynamics simulations.

  The journal of physical chemistry. A 20110630

• Unraveling terminal C-domain-mediated condensation in fungal biosynthesis of imidazoindolone metabolites.

  Biochemistry 20110628

• Elucidation of the protonation states of the catalytic residues in mtKasA: implications for inhibitor design.

  Biochemistry 20110628

• Phase I dose-escalation study to determine the safety, pharmacokinetics and pharmacodynamics of brivanib alaninate in combination with full-dose cetuximab in patients with advanced gastrointestinal malignancies who have failed prior therapy.

  British journal of cancer 20110628

• Dynamical reweighting: improved estimates of dynamical properties from simulations at multiple temperatures.

  The Journal of chemical physics 20110628

• Optimal use of data in parallel tempering simulations for the construction of discrete-state Markov models of biomolecular dynamics.

  The Journal of chemical physics 20110628

• Inhibition of alanine aminotransferase in silico and in vivo promotes mitochondrial metabolism to impair malignant growth.

  The Journal of biological chemistry 20110624

• Solid-state NMR ensemble dynamics as a mediator between experiment and simulation.

  Biophysical journal 20110622

• Covalent structural changes in unfolded GroES that lead to amyloid fibril formation detected by NMR: insight into intrinsically disordered proteins.

  The Journal of biological chemistry 20110617

• Btk regulation in human and mouse B cells via protein kinase C phosphorylation of IBtkγ.

  Blood 20110616

• A theoretical study of the XP and NEXAFS spectra of alanine: gas phase molecule, crystal, and adsorbate at the ZnO(10 ̅10) surface.

  Physical chemistry chemical physics : PCCP 20110614

• Conformational and aggregation properties of a PEGylated alanine-rich polypeptide.

  Biomacromolecules 20110613

• Direct assessment of the α-helix nucleation time.

  The journal of physical chemistry. B 20110609

• Pleiotropic impact of a single lysine mutation on biosynthesis of and catalysis by N-methyltryptophan oxidase.

  Biochemistry 20110607

• Artificial lantipeptides from in vitro translations.

  Chemical communications (Cambridge, England) 20110607

• Connected cavity structure enables prenyl elongation across the dimer interface in mutated geranylfarnesyl diphosphate synthase from Methanosarcina mazei.

  Biochemical and biophysical research communications 20110603

• Indirect reversed-phase high-performance liquid chromatographic and direct thin-layer chromatographic enantioresolution of (R,S)-Cinacalcet.

  Biomedical chromatography : BMC 20110601

• How many hydrogen-bonded α-turns are possible?

  Journal of molecular modeling 20110601

• Towards a structural understanding of the smallest known oncoprotein: investigation of the bovine papillomavirus E5 protein using solution-state NMR.

  Biochimica et biophysica acta 20110601

• A phase I study to determine the safety, pharmacokinetics and pharmacodynamics of a dual VEGFR and FGFR inhibitor, brivanib, in patients with advanced or metastatic solid tumors.

  Annals of oncology : official journal of the European Society for Medical Oncology 20110601

• Alanine-scanning mutagenesis of selected residues in the N-terminal region alters the functionality of LuxO: lessons from a natural variant LuxOPL91.

  Journal of medical microbiology 20110601

• Water permeation dynamics of AqpZ: a tale of two states.

  Biochimica et biophysica acta 20110601

• Design of Deinococcus radiodurans thioredoxin reductase with altered thioredoxin specificity using computational alanine mutagenesis.

  Protein science : a publication of the Protein Society 20110601

• Invariant natural killer T-cell-deficient mice display increased CCl₄ -induced hepatitis associated with CXCL1 over-expression and neutrophil infiltration.

  European journal of immunology 20110601

• Synthesis and evaluation of heteroarylalanine diacids as potent and selective neutral endopeptidase inhibitors.

  Bioorganic & medicinal chemistry letters 20110601

• Adsorption of amino acids (ALA, CYS, HIS, MET) on zeolites: fourier transform infrared and Raman spectroscopy investigations.

  Astrobiology 20110601

• In vivo MRSI of hyperpolarized [1-(13)C]pyruvate metabolism in rat hepatocellular carcinoma.

  NMR in biomedicine 20110601

• Amyloid neuropathy with transthyretin mutations: overview and unique Ala97Ser in Taiwan.

  Acta neurologica Taiwanica 20110601

• First report of a novel extended-spectrum beta-lactamase KOXY-2 producing Klebsiella oxytoca that hydrolyses cefotaxime and ceftazidime.

  Journal of chemotherapy (Florence, Italy) 20110601

• The Thr- and Ala-rich hyperactive antifreeze protein from inchworm folds as a flat silk-like β-helix.

  Biochemistry 20110531

• Casein kinase-2α1 induces hypertrophic response by phosphorylation of histone deacetylase 2 S394 and its activation in the heart.

  Circulation 20110531

• Original predictive approach to the compressibility of pharmaceutical powder mixtures based on the Kawakita equation.

  International journal of pharmaceutics 20110530

• Aspartate 102 in the heme domain of soluble guanylyl cyclase has a key role in NO activation.

  Biochemistry 20110524

• Positions of polar amino acids alter interactions between transmembrane segments and detergents.

  Biochemistry 20110517

• Mutations that replace aromatic side chains promote aggregation of the Alzheimer's Aβ peptide.

  Biochemistry 20110517

• Reduction of plasma membrane glutamate transport potentiates insulin but not glucagon secretion in pancreatic islet cells.

  Molecular and cellular endocrinology 20110516

• Clinical and histopathological features of familial amyloidotic polyneuropathy with transthyretin Val30Ala in a Chinese family.

  Journal of the neurological sciences 20110515

• Cys-X scanning for expansion of active-site residues and modulation of catalytic functions in a glutathione transferase.

  The Journal of biological chemistry 20110513

• Structure-function analysis of the bacterial expansin EXLX1.

  The Journal of biological chemistry 20110513

• Ala-9Val polymorphism of Mn-SOD gene in sickle cell anemia.

  Genetics and molecular research : GMR 20110510

• Insights on the mechanism of proton transfer reactions in amino acids.

  Physical chemistry chemical physics : PCCP 20110507

• A step toward the wet surface chemistry of glycine and alanine on Cu{110}: destabilization and decomposition in the presence of near-ambient water vapor.

  Journal of the American Chemical Society 20110504

• Dietary L-arginine supplementation differentially regulates expression of lipid-metabolic genes in porcine adipose tissue and skeletal muscle.

  The Journal of nutritional biochemistry 20110501

• Molecular dynamics simulations of the minor ampullate spidroin modular amino acid sequence from Parawixia bistriatra: insights into silk tertiary structure and fibre formation.

  Journal of molecular modeling 20110501

• Resveratrol and genistein as adenosine triphosphate-depleting agents in fat cells.

  Metabolism: clinical and experimental 20110501

• Intravenous arginine and human skin graft donor site healing: a randomized controlled trial.

  Burns : journal of the International Society for Burn Injuries 20110501

• Synthesis of 'clickable' acylhomoserine lactone quorum sensing probes: unanticipated effects on mammalian cell activation.

  Bioorganic & medicinal chemistry letters 20110501

• Large proportion of amyotrophic lateral sclerosis cases in Sardinia due to a single founder mutation of the TARDBP gene.

  Archives of neurology 20110501

• Metabolism and disposition of [14C]brivanib alaninate after oral administration to rats, monkeys, and humans.

  Drug metabolism and disposition: the biological fate of chemicals 20110501

• Removal of L-alanine from the production of L-2-aminobutyric acid by introduction of alanine racemase and D-amino acid oxidase.

  Applied microbiology and biotechnology 20110501

• Enantioselective bioaccumulation and toxic effects of metalaxyl in earthworm Eisenia foetida.

  Chemosphere 20110501

• A randomized controlled trial of rebamipide plus rabeprazole for the healing of artificial ulcers after endoscopic submucosal dissection.

  Journal of gastroenterology 20110501

• Multienzyme-modified biosensing surface for the electrochemical analysis of aspartate transaminase and alanine transaminase in human plasma.

  Analytical and bioanalytical chemistry 20110501

• Structure and behaviour of the free radicals generated in gamma irradiated amino acid and iminodiacetic acid derivatives.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110501

• On easy implementation of a variant of the replica exchange with solute tempering in GROMACS.

  Journal of computational chemistry 20110501

• Global analysis for functional residues of histone variant Htz1 using the comprehensive point mutant library.

  Genes to cells : devoted to molecular & cellular mechanisms 20110501

• A national dosimetric audit of IMRT.

  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110501

• Novel SCN1A mutation in a proband with malignant migrating partial seizures of infancy.

  Archives of neurology 20110501

• The temperature intervals with global exchange of replicas empirical accelerated sampling method: parameter sensitivity and extension to a complex molecular system.

  Journal of computational chemistry 20110430

• A validated chiral liquid chromatographic method for the enantiomeric separation of safinamide mesilate, a new anti-Parkinson drug.

  Journal of pharmaceutical and biomedical analysis 20110428

• Water-mediated conformations of the alanine dipeptide as revealed by distributed umbrella sampling simulations, quantum mechanics based calculations, and experimental data.

  The journal of physical chemistry. B 20110428

• Activity map of the Escherichia coli RNA polymerase bridge helix.

  The Journal of biological chemistry 20110422

• A specific two-pore domain potassium channel blocker defines the structure of the TASK-1 open pore.

  The Journal of biological chemistry 20110422

• Functional and structural roles of residues in the third extramembrane segment of adrenal cytochrome b561.

  Biochemistry 20110419

• Importance of each residue within secretin for receptor binding and biological activity.

  Biochemistry 20110412

• Regulation of the incorporation of tissue factor into microparticles by serine phosphorylation of the cytoplasmic domain of tissue factor.

  The Journal of biological chemistry 20110408

• Water-induced physical gelation of organic solvents by N-(n-alkylcarbamoyl)-L-alanine amphiphiles.

  Langmuir : the ACS journal of surfaces and colloids 20110405

• Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine.

  Neurotoxicity research 20110401

• Manganese superoxide dismutase dimorphism relationship with severity and prognosis in cardiogenic shock due to dilated cardiomyopathy.

  Free radical research 20110401

• Ala16Val SOD2 polymorphism is associated with higher pregnancy rates in in vitro fertilization cycles.

  Fertility and sterility 20110401

• Electrostatic clustering and free energy calculations provide a foundation for protein design and optimization.

  Annals of biomedical engineering 20110401

• Genetic evidence for a novel interaction between transcriptional activator SoxS and region 4 of the σ(70) subunit of RNA polymerase at class II SoxS-dependent promoters in Escherichia coli.

  Journal of molecular biology 20110401

• Phenotypic, proteomic, and genomic characterization of a putative ABC-transporter permease involved in Listeria monocytogenes biofilm formation.

  Foodborne pathogens and disease 20110401

• Identification of the roles of conserved charged residues in the extracellular domain of an epithelial sodium channel (ENaC) subunit by alanine mutagenesis.

  American journal of physiology. Renal physiology 20110401

• Why does the inner-helix mutation A413C double the stoichiometry of Kv1.3 channel block by emopamil but not by verapamil?

  Molecular pharmacology 20110401

• Helix 8 of the M1 muscarinic acetylcholine receptor: scanning mutagenesis delineates a G protein recognition site.

  Molecular pharmacology 20110401

• Synthesis of peptides containing 5-hydroxytryptophan, oxindolylalanine, N-formylkynurenine and kynurenine.

  Journal of peptide science : an official publication of the European Peptide Society 20110401

• Application of double spin echo spiral chemical shift imaging to rapid metabolic mapping of hyperpolarized [1-¹³C]-pyruvate.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20110401

• Phase II, open-label study of brivanib as first-line therapy in patients with advanced hepatocellular carcinoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110401

• Effect of pesticides on plant growth promoting traits of greengram-symbiont, Bradyrhizobium sp. strain MRM6.

  Bulletin of environmental contamination and toxicology 20110401

• Study of stereoselective interactions of carbamoylated quinine and quinidine with 3,5-dinitrobenzoyl α-amino acids using VCD spectroscopy in the region of C−H stretching vibrations.

  Chirality 20110401

• Brivanib alaninate for cancer.

  Expert opinion on investigational drugs 20110401

• Implementation of alanine/EPR as transfer dosimetry system in a radiotherapy audit programme in Belgium.

  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110401

• Dose response of alanine detectors irradiated with carbon ion beams.

  Medical physics 20110401

• Fully analytic energy gradient in the fragment molecular orbital method.

  The Journal of chemical physics 20110328

• Strong water-mediated friction asymmetry and surface dynamics of zwitterionic solids at ambient conditions: L-alanine as a case study.

  The Journal of chemical physics 20110328

• Mutations in the transmembrane domain M3 generate spontaneously open orphan glutamate δ1 receptor.

  Brain research 20110325

• An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity.

  Biochemistry 20110322

• Practical syntheses of a CXCR3 antagonist.

  The Journal of organic chemistry 20110318

• Asymmetric synthesis of α-methyl-α-amino acids via diastereoselective alkylation of (1S)-(+)-3-carene derived tricyclic iminolactone.

  The Journal of organic chemistry 20110318

• Solomonamides A and B, new anti-inflammatory peptides from Theonella swinhoei.

  Organic letters 20110318

• Surface functionalization of virus-like particles by direct conjugation using azide-alkyne click chemistry.

  Bioconjugate chemistry 20110316

• Increased bioavailability of tricin-amino acid derivatives via a prodrug approach.

  Journal of medicinal chemistry 20110310

• Dinuclear Zn(II) complex catalyzed phosphodiester cleavage proceeds via a concerted mechanism: a density functional theory study.

  Journal of the American Chemical Society 20110309

• Heat maps for intramolecular communication in an RNP enzyme encoding glutamine.

  Structure (London, England : 1993) 20110309

• Structure, adsorption and magnetic properties of chiral metal-organic frameworks bearing linear trinuclear secondary building blocks.

  Dalton transactions (Cambridge, England : 2003) 20110307

• SSTR1- and SSTR3-selective somatostatin analogues.

  Chembiochem : a European journal of chemical biology 20110307

• Dose uncertainty in radiotherapy of patients with head and neck cancer measured by in vivo ESR/alanine dosimetry using a mouthpiece.

  Physics in medicine and biology 20110307

• Indirect enantioresolution of (R,S)-mexiletine by reversed-phase high-performance liquid chromatography via diastereomerization with [(S,S)-O,O'-di-p-toluoyl tartaric acid anhydride], (S)-naproxen and nine chiral reagents synthesized as variants of Marfey's reagent.

  Biomedical chromatography : BMC 20110301

• Effect of environmental factors on the biosynthesis of the neuro-excitatory amino acid β-ODAP (β-N-oxalyl-L-α,β-diaminopropionic acid) in callus tissue of Lathyrus sativus.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110301

• Evaluation of Bacillus strains as model systems for the work on Bacillus anthracis spores.

  International journal of food microbiology 20110301

• Different Staphylococcus aureus whole bacteria mutated in putative pro-inflammatory membrane components have similar cytokine inducing activity.

  Immunobiology 20110301

• LAT1 overexpression and function compensates downregulation of ASCT2 in an in vitro model of renal proximal tubule cell ageing.

  Molecular and cellular biochemistry 20110301

• Novel oxidative modifications in redox-active cysteine residues.

  Molecular & cellular proteomics : MCP 20110301

• Molecular characterization of tissue-nonspecific alkaline phosphatase with an Ala to Thr substitution at position 116 associated with dominantly inherited hypophosphatasia.

  Biochimica et biophysica acta 20110301

• Enhanced retention of linuron, alachlor and metalaxyl in sandy soil columns intercalated with wood barriers.

  Chemosphere 20110301

• Delayed biochemical changes induced by mercury intoxication are prevented by zinc pre-exposure.

  Ecotoxicology and environmental safety 20110301

• PDZK1 binding and serine phosphorylation regulate subcellular trafficking of organic anion transport protein 1a1.

  American journal of physiology. Gastrointestinal and liver physiology 20110301

• Identification of an L-alanine export system in Escherichia coli and isolation and characterization of export-deficient mutants.

  FEMS microbiology letters 20110301

• Functional epitopes for site 1 of human prolactin.

  Biochemistry 20110301

• Specificity of the volume-activated amino acid efflux pathway in cultured human breast cancer cells.

  General physiology and biophysics 20110301

• Calibration of helical tomotherapy machine using EPR/alanine dosimetry.

  Medical physics 20110301

• Histidine and carnosine alleviated hepatic steatosis in mice consumed high saturated fat diet.

  European journal of pharmacology 20110225

• Simultaneous quantification and identification of individual chemicals in metabolite mixtures by two-dimensional extrapolated time-zero (1)H-(13)C HSQC (HSQC(0)).

  Journal of the American Chemical Society 20110216

• Peptide conformational preferences in osmolyte solutions: transfer free energies of decaalanine.

  Journal of the American Chemical Society 20110216

• Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis.

  Biophysical journal 20110216

• A novel, simple method to simulate gelling process of injectable biodegradable in situ forming drug delivery system based on determination of electrical conductivity.

  International journal of pharmaceutics 20110214

• Enhanced in vitro transbuccal drug delivery of ondansetron HCl.

  International journal of pharmaceutics 20110214

• Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy.

  Journal of medicinal chemistry 20110210

• Bond dissociation of the dipeptide dialanine and its derivative alanine anhydride induced by low energy electrons.

  The Journal of chemical physics 20110207

• Protein folding in a reverse micelle environment: the role of confinement and dehydration.

  The Journal of chemical physics 20110207

• Aβ40(L17A/F19A) mutant diminishes the aggregation and neurotoxicity of Aβ40.

  Biochemical and biophysical research communications 20110204

• Progressive neuropathology and cognitive decline in a single Arctic APP transgenic mouse model.

  Neurobiology of aging 20110201

• Stereoselective metabolism of benalaxyl in liver microsomes from rat and rabbit.

  Chirality 20110201

• Protective effect of rebamipide against Helicobacter pylori-CagA-induced effects on gastric epithelial cells.

  Digestive diseases and sciences 20110201

• Quality of random number generators significantly affects results of Monte Carlo simulations for organic and biological systems.

  Journal of computational chemistry 20110201

• Intramolecular interactions of L-phenylalanine: Valence ionization spectra and orbital momentum distributions of its fragment molecules.

  Journal of computational chemistry 20110201

• Necessary and sufficient conditions for the asymmetric synthesis of chiral amines using ω-aminotransferases.

  Biotechnology and bioengineering 20110201

• Delineation of substrate selection and anaplerosis in tricarboxylic acid cycle of the heart by 13C NMR spectroscopy and mass spectrometry.

  NMR in biomedicine 20110201

• Energy substrate utilization in the common brushtailed possum (Trichosurus vulpecula) using intravenous tolerance tests.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20110201

• The essential role of the Cu(II) state of Sco in the maturation of the Cu(A) center of cytochrome oxidase: evidence from H135Met and H135SeM variants of the Bacillus subtilis Sco.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20110201

• Salting-out phenomenon and 1-octanol/water partition coefficient of metalaxyl pesticide.

  Chemosphere 20110201

• Direct and indirect control of orexin/hypocretin neurons by glycine receptors.

  The Journal of physiology 20110201

• Interaction between CK2α and CK2β, the subunits of protein kinase CK2: thermodynamic contributions of key residues on the CK2α surface.

  Biochemistry 20110201

• Molecular and structural insight into the role of key residues of thrombospondin-1 and calreticulin in thrombospondin-1-calreticulin binding.

  Biochemistry 20110201

• Relationship between neuropathology and disease progression in the SOD1(G93A) ALS mouse.

  Experimental neurology 20110201

• Multiple endocrine neoplasia type 2B with a RET proto-oncogene A883F mutation displays a more indolent form of medullary thyroid carcinoma compared with a RET M918T mutation.

  Thyroid : official journal of the American Thyroid Association 20110201

• Exploring the conformational changes of the ATP binding site of gyrase B from Escherichia coli complexed with different established inhibitors by using molecular dynamics simulation: protein-ligand interactions in the light of the alanine scanning and free energy decomposition methods.

  Journal of molecular graphics & modelling 20110201

• Utilization of IR spectral detailed analysis for coordination mode determination in novel Zn-cyclen-aminoacid complexes.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110201

• Evidence for the presence of a critical disulfide bond in the mouse EP3γ receptor.

  Prostaglandins & other lipid mediators 20110201

• DL-alaninium semi-oxalate monohydrate.

  Acta crystallographica. Section C, Crystal structure communications 20110201

• Global energy minimization of alanine dipeptide via barrier function methods.

  Computational biology and chemistry 20110201

• What the halted phase III γ-secretase inhibitor trial may (or may not) be telling us.

  Annals of neurology 20110201

• Molecular modeling of human lanosterol 14α-demethylase complexes with substrates and their derivatives.

  Biochemistry. Biokhimiia 20110201

• Thermal development of latent fingermarks on porous surfaces--further observations and refinements.

  Forensic science international 20110130

• Fmoc-chemistry of a stable phosphohistidine analogue.

  Chemical communications (Cambridge, England) 20110128

• Kinetics of reactions of the Actinomadura R39 DD-peptidase with specific substrates.

  Biochemistry 20110125

• Selective adsorption and chiral amplification of amino acids in vermiculite clay-implications for the origin of biochirality.

  Physical chemistry chemical physics : PCCP 20110121

• Asymmetric synthesis of sterically and electronically demanding linear ω-trifluoromethyl containing amino acids via alkylation of chiral equivalents of nucleophilic glycine and alanine.

  The Journal of organic chemistry 20110121

• Spatial decomposition of solvation free energy based on the 3D integral equation theory of molecular liquid: application to miniproteins.

  The journal of physical chemistry. B 20110120

• Protein thiocarboxylate-dependent methionine biosynthesis in Wolinella succinogenes.

  Journal of the American Chemical Society 20110119

• Generation of pseudocontact shifts in protein NMR spectra with a genetically encoded cobalt(II)-binding amino acid.

  Angewandte Chemie (International ed. in English) 20110117

• Gender differences in the effects of peroxisome proliferator-activated receptor γ2 gene polymorphisms on metabolic adversity in patients with schizophrenia or schizoaffective disorder.

  Progress in neuro-psychopharmacology & biological psychiatry 20110115

• Evaluation of small bowel blood flow in healthy subjects receiving low-dose aspirin.

  World journal of gastroenterology 20110114

• Discovery of a series of phosphonic acid-containing thiazoles and orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase.

  Journal of medicinal chemistry 20110113

• Optimization of partial multicanonical molecular dynamics simulations applied to an alanine dipeptide in explicit water solvent.

  Physical chemistry chemical physics : PCCP 20110107

• 3-Phosphono-L-alanine as pyrophosphate mimic for DNA synthesis using HIV-1 reverse transcriptase.

  Organic & biomolecular chemistry 20110107

• A moment invariant for evaluating the chirality of three-dimensional objects.

  Journal of the Royal Society, Interface 20110106

• Effects of amyloid-β peptides on the serotoninergic 5-HT1A receptors in the rat hippocampus.

  Neurobiology of aging 20110101

• Study on the interaction between human serum albumin and a novel bioactive acridine derivative using optical spectroscopy.

  Luminescence : the journal of biological and chemical luminescence 20110101

• Fusarium verticillioides: evaluation of fumonisin production and effect of fungicides on in vitro inhibition of mycelial growth.

  Mycopathologia 20110101

• Biological hydrogen production by the algal biomass Chlorella vulgaris MSU 01 strain isolated from pond sediment.

  Bioresource technology 20110101

• Comparing experimental and computational alanine scanning techniques for probing a prototypical protein-protein interaction.

  Protein engineering, design & selection : PEDS 20110101

• Brain glutamine synthesis requires neuronal-born aspartate as amino donor for glial glutamate formation.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110101

• The role of aromatic side-chains in amyloid growth and membrane interaction of the islet amyloid polypeptide fragment LANFLVH.

  European biophysics journal : EBJ 20110101

• A novel ACTA1 mutation resulting in a severe congenital myopathy with nemaline bodies, intranuclear rods and type I fibre predominance.

  Neuromuscular disorders : NMD 20110101

• The role of alanine 163 in solute permeability of Leishmania major aquaglyceroporin LmAQP1.

  Molecular and biochemical parasitology 20110101

• Rebamipide has the potential to reduce the intensity of NSAID-induced small intestinal injury: a double-blind, randomized, controlled trial evaluated by capsule endoscopy.

  Journal of gastroenterology 20110101

• Oligomeric structure of a cathelicidin antimicrobial peptide in dodecylphosphocholine micelle determined by NMR spectroscopy.

  Biochimica et biophysica acta 20110101

• The transmembrane domain 6 of vacuolar H(+)-pyrophosphatase mediates protein targeting and proton transport.

  Biochimica et biophysica acta 20110101

• Receptor-mediated ER export of human MHC class I molecules is regulated by the C-terminal single amino acid.

  Traffic (Copenhagen, Denmark) 20110101

• Mapping the folding pathway of the transmembrane protein DsbB by protein engineering.

  Protein engineering, design & selection : PEDS 20110101

• Very fast magic angle spinning (1)H-(14)N 2D solid-state NMR: sub-micro-liter sample data collection in a few minutes.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20110101

• Effects of insulin-like growth factor-I administration on in vivo regulation of urea synthesis in normal subjects and patients with cirrhosis.

  Liver international : official journal of the International Association for the Study of the Liver 20110101

• Uncertainty attributed to signal averaging in a single averaged alanine EPR spectrum for low-dose applications.

  Radiation protection dosimetry 20110101

• Involvement of glutamine-238 in the substrate specificity of human laeverin/aminopeptidase Q.

  Biological & pharmaceutical bulletin 20110101

• Characterization of a novel mutation in the CRYBB2 gene associated with autosomal dominant congenital posterior subcapsular cataract in a Chinese family.

  Molecular vision 20110101

• Hb Nebraska [β86(F2)Ala→Ile (HBB:c.259G>A;260C>T)]: a unique high oxygen affinity hemoglobin variant with a double nucleotide substitution within the same codon.

  Hemoglobin 20110101

• Induction kinetics of the Staphylococcus aureus cell wall stress stimulon in response to different cell wall active antibiotics.

  BMC microbiology 20110101

• Oligonucleotide analogs with peptide internucleotide linkages.

  Nucleosides, nucleotides & nucleic acids 20110101

• Three hydrophobic amino acids in Escherichia coli HscB make the greatest contribution to the stability of the HscB-IscU complex.

  BMC biochemistry 20110101

• New pathway links γ-secretase to inflammation and memory while sparing notch.

  Annals of neurology 20110101

• Nascent proteomes of ischemic-injured and ischemic-tolerant neuronal cells.

  International journal of computational biology and drug design 20110101

• Alanine zipper-like coiled-coil domains are necessary for homotypic dimerization of plant GAGA-factors in the nucleus and nucleolus.

  PloS one 20110101

• Contributions of hepatic gluconeogenesis suppression and compensative glycogenolysis on the glucose-lowering effect of CS-917, a fructose 1,6-bisphosphatase inhibitor, in non-obese type 2 diabetes Goto-Kakizaki rats.

  Journal of pharmacological sciences 20110101

• [Analysis of the FABP2 gene Ala54Thr polymorphism in non-obese and obese Chinese].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20110101

• The role of the disulfide bridge in the stability and structural integrity of ovalbumin evaluated by site-directed mutagenesis.

  Bioscience, biotechnology, and biochemistry 20110101

• BCL-2 (-938C > A) polymorphism is associated with breast cancer susceptibility.

  BMC medical genetics 20110101

• Fructose-1, 6-bisphosphatase inhibitors for reducing excessive endogenous glucose production in type 2 diabetes.

  Handbook of experimental pharmacology 20110101

• Assembly of collagen fibril meshes using gold nanoparticles functionalized with tris(hydroxymethyl)phosphine-alanine as multivalent cross-linking agents.

  Journal of molecular recognition : JMR 20110101

• Kinetic resolution of 3-fluoroalanine using a fusion protein of D-amino acid oxidase with Vitroscilla hemoglobin.

  Bioscience, biotechnology, and biochemistry 20110101

• Structure-based modification of D-alanine-D-alanine ligase from Thermotoga maritima ATCC 43589 for depsipeptide synthesis.

  Bioscience, biotechnology, and biochemistry 20110101

• Effect of the quality of dietary amino acids composition on the urea synthesis in rats.

  Journal of nutritional science and vitaminology 20110101

• PPAR-gamma2 pro12Ala polymorphism is associated with post-challenge abnormalities of glucose homeostasis in children and adolescents with obesity.

  Journal of pediatric endocrinology & metabolism : JPEM 20110101

• Experimental and theoretical studies of vacuum-ultraviolet electronic circular dichroism of hydroxy acids in aqueous solution.

  Chirality 20110101

• Gastric ulcerogenic and healing impairment actions of alendronate, a nitrogen-containing bisphosphonate - prophylactic effects of rebamipide.

  Current pharmaceutical design 20110101

• Isolation of a mutant auxotrophic for L-alanine and identification of three major aminotransferases that synthesize L-alanine in Escherichia coli.

  Bioscience, biotechnology, and biochemistry 20110101

• Quantitation of newly synthesized proteins by pulse labeling with azidohomoalanine.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Application of XANES profiles to X-ray spectromicroscopy for biomedical specimens: Part I. Discrimination of macromolecules with sulfur atoms.

  Journal of X-ray science and technology 20110101

• Fibrous architectures and organogels of tris(phenylethynylphenyl)adamantane molecules with amino acid moieties: their solvato-controlled helicity induction.

  Chirality 20110101

• The C-terminal domain of the novel essential protein Gcp is critical for interaction with another essential protein YeaZ of Staphylococcus aureus.

  PloS one 20110101

• Renin-angiotensin-aldosterone system genes and nonarteritic anterior ischemic optic neuropathy.

  Molecular vision 20110101

• Effects of the Crotalus durissus terrificus snake venom on hepatic metabolism and oxidative stress.

  Journal of biochemical and molecular toxicology 20110101

• Chemoselective modification of viral proteins bearing metabolically introduced 'clickable' amino acids and sugars.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Validation of ELISA methods for quantification of total tau and phosporylated-tau181 in human cerebrospinal fluid with measurement in specimens from two Alzheimer's disease studies.

  Journal of Alzheimer's disease : JAD 20110101

• Global regulatory systems operating in Bacilysin biosynthesis in Bacillus subtilis.

  Journal of molecular microbiology and biotechnology 20110101

• Use of industrial byproducts to filter phosphorus and pesticides in golf green drainage water.

  Journal of environmental quality 20110101

• Alanine racemase mutants of Burkholderia pseudomallei and Burkholderia mallei and use of alanine racemase as a non-antibiotic-based selectable marker.

  PloS one 20110101

• The adsorption and degradation of chlorpyriphos-methyl, pendimethalin and metalaxyl in solid urban waste compost.

  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20110101

• E. coli histidine triad nucleotide binding protein 1 (ecHinT) is a catalytic regulator of D-alanine dehydrogenase (DadA) activity in vivo.

  PloS one 20110101

• Healing effects of rebamipide and omeprazole in Helicobacter pylori-positive gastric ulcer patients after eradication therapy: a randomized double-blind, multinational, multi-institutional comparative study.

  Digestion 20110101

• [Critical amino acids of ornitin decarboxylase degron: the presence and C-terminal arrangement is insufficient for alfa-fetoprotein degradation].

  Molekuliarnaia biologiia 20110101

• Cellular immune responses to nine Mycobacterium tuberculosis vaccine candidates following intranasal vaccination.

  PloS one 20110101

• Genetic characterization of conserved charged residues in the bacterial flagellar type III export protein FlhA.

  PloS one 20110101

• Future treatment option for hepatocellular carcinoma: a focus on brivanib.

  Digestive diseases (Basel, Switzerland) 20110101

• An inserted α/β subdomain shapes the catalytic pocket of Lactobacillus johnsonii cinnamoyl esterase.

  PloS one 20110101

• Altered tryptophan and alanine transport in fibroblasts from boys with attention-deficit/hyperactivity disorder (ADHD): an in vitro study.

  Behavioral and brain functions : BBF 20110101

• Mechanism of the interaction between the intrinsically disordered C-terminus of the pro-apoptotic ARTS protein and the Bir3 domain of XIAP.

  PloS one 20110101

• Improving a natural CaMKII inhibitor by random and rational design.

  PloS one 20110101

• BACE-1 inhibition prevents the γ-secretase inhibitor evoked Aβ rise in human neuroblastoma SH-SY5Y cells.

  Journal of biomedical science 20110101

• Glucose metabolism in Trypanosoma cruzi.

  Essays in biochemistry 20110101

• Digestion under duress: nutrient acquisition and metabolism during hypoxia in the Pacific hagfish.

  Physiological and biochemical zoology : PBZ 20110101

• A multi-tissue type genome-scale metabolic network for analysis of whole-body systems physiology.

  BMC systems biology 20110101

• The improvement of an anti-CD22 immunotoxin: conversion to single-chain and disulfide stabilized form and affinity maturation by alanine scan.

  mAbs 20110101

• Gene cloning and characterization of α-amino acid ester acyl transferase in Empedobacter brevis ATCC14234 and Sphingobacterium siyangensis AJ2458.

  Bioscience, biotechnology, and biochemistry 20110101

• Interacting with γ-secretase for treating Alzheimer's disease: from inhibition to modulation.

  Current medicinal chemistry 20110101

• A human monoclonal antibody with neutralizing activity against highly divergent influenza subtypes.

  PloS one 20110101

• Comparative effects of short-term and long-term insulin-induced hypoglycemia on glucose production in the perfused livers of weaned rats.

  Pharmacological reports : PR 20110101

• PPARγ2 gene Pro12Ala and PPARα gene Leu162Val single nucleotide polymorphisms interact with dietary intake of fat in determination of plasma lipid concentrations.

  Journal of nutrigenetics and nutrigenomics 20110101

• Probing the active site of the deoxynucleotide N-hydrolase Rcl encoded by the rat gene c6orf108.

  The Journal of biological chemistry 20101231

• Alanine methyl groups as NMR probes of molecular structure and dynamics in high-molecular-weight proteins.

  Journal of the American Chemical Society 20101229

• Multi-chelation approach towards natural product-like skeletons: one-pot access to a nitrogen-containing tetracyclic framework from AlaAla dipeptide.

  Chemical communications (Cambridge, England) 20101228

• Understanding free-energy perturbation calculations through a model of harmonic oscillators: theory and implications to improve the sampling efficiency by molecular simulation.

  The Journal of chemical physics 20101228

• The effect of active-site isoleucine to alanine mutation on the DHFR catalyzed hydride-transfer.

  Chemical communications (Cambridge, England) 20101221

• Terahertz and far infrared spectroscopy of alanine-rich peptides having variable ellipticity.

  Optics express 20101220

• Experimental and computational thermochemical study of α-alanine (DL) and β-alanine.

  The journal of physical chemistry. B 20101216

• Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 in patients with fatty liver diseases.

  World journal of gastroenterology 20101214

• Combinatorial alanine substitution enables rapid optimization of cytochrome P450BM3 for selective hydroxylation of large substrates.

  Chembiochem : a European journal of chemical biology 20101210

• Molecular dynamics simulations of structure and dynamics of organic molecular crystals.

  Physical chemistry chemical physics : PCCP 20101207

• (1)H NMR-based metabonomic investigation of the effect of two different exercise sessions on the metabolic fingerprint of human urine.

  Journal of proteome research 20101203

• Ultrabright and bioorthogonal labeling of cellular targets using semiconducting polymer dots and click chemistry.

  Angewandte Chemie (International ed. in English) 20101203

• Selective noradrenergic vulnerability in α-synuclein transgenic mice.

  Neurobiology of aging 20101201

• Antitumor effect of mSurvivinThr34→Ala in murine colon carcinoma when administered intravenously.

  Medical oncology (Northwood, London, England) 20101201

• Management of recurrence of symptoms of gastroesophageal reflux disease: synergistic effect of rebamipide with 15 mg lansoprazole.

  Digestive diseases and sciences 20101201

• Rebamipide inhibits tumor necrosis factor-α-induced interleukin-8 expression by suppressing the NF-κB signal pathway in human umbilical vein endothelial cells.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20101201

• Alanine-scanning mutations of the BMP-binding domain of recombinant secretory bovine spp24 affect cytokine binding.

  Connective tissue research 20101201

• Purification and biochemical characterization of Mur ligases from Staphylococcus aureus.

  Biochimie 20101201

• Conformation dependence of the DαDα stretch mode in peptides: Side-chain influence in dipeptide structures.

  Biopolymers 20101201

• Antibiotic-induced psychosis: a link to D-alanine?

  Medical hypotheses 20101201

• Mapping the ligand binding sites of kainate receptors: molecular determinants of subunit-selective binding of the antagonist [3H]UBP310.

  Molecular pharmacology 20101201

• Neuropathology of the recessive A673V APP mutation: Alzheimer disease with distinctive features.

  Acta neuropathologica 20101201

• Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20101201

• The design and synthesis of alanine-based indolicidin derivatives with identical physicochemical properties and their separation using capillary electrophoresis.

  Analytical and bioanalytical chemistry 20101201

• Comparison of aromatic NH···π, OH···π, and CH···π interactions of alanine using MP2, CCSD, and DFT methods.

  Journal of computational chemistry 20101201

• Identification of an intracellular microdomain of the P2X7 receptor that is crucial in basolateral membrane targeting in epithelial cells.

  FEBS letters 20101201

• Click synthesis and biologic evaluation of (R)- and (S)-2-amino-3-[1-(2-[18F]fluoroethyl)-1H-[1,2,3]triazol-4-yl]propanoic acid for brain tumor imaging with positron emission tomography.

  Molecular imaging 20101201

• A concise and scalable route to L-azidohomoalanine.

  Nature protocols 20101201

• Carbon utilization profiles of Fusarium virguliforme isolates.

  Canadian journal of microbiology 20101201

• Alanine/EPR dosimetry applied to the verification of a total body irradiation protocol and treatment planning dose calculation using a humanoid phantom.

  Medical physics 20101201

• Wavelet analysis used for spectral background removal in the determination of glucose from near-infrared single-beam spectra.

  Analytica chimica acta 20101129

• Genetics. Gamma-secretase and human disease.

  Science (New York, N.Y.) 20101119

• Quantification of cystatin C in cerebrospinal fluid from various neurological disorders and correlation with G73A polymorphism in CST3.

  Brain research 20101118

• What can be inferred from the interruption of the semagacestat trial for treatment of Alzheimer's disease?

  Biological psychiatry 20101115

• Green synthesis of α,β- and β,β-dipeptides under solvent-free conditions.

  The Journal of organic chemistry 20101105

• Pyridylalanine (Pal)-peptide catalyzed enantioselective allenoate additions to N-acyl imines proceed via an atypical 'aza-Morita-Baylis-Hillman' mechanism.

  Organic letters 20101105

• The molecular recognition mechanism for superoxide dismutase presequence binding to the mitochondrial protein import receptor Tom20 from Oryza sativa involves an LRTLA motif.

  The journal of physical chemistry. B 20101104

• Esterification of an unnatural amino acid structurally deviating from canonical amino acids promotes its uptake and incorporation into proteins in mammalian cells.

  Chembiochem : a European journal of chemical biology 20101102

• Positional effects on helical Ala-based peptides.

  Biochemistry 20101102

• Whole body protein kinetics measured with a non-invasive method in severely burned children.

  Burns : journal of the International Society for Burn Injuries 20101101

• Palmitoylation of CD36/FAT regulates the rate of its post-transcriptional processing in the endoplasmic reticulum.

  Biochimica et biophysica acta 20101101

• Metabolism, excretion, and pharmacokinetics of oral brivanib in patients with advanced or metastatic solid tumors.

  Drug metabolism and disposition: the biological fate of chemicals 20101101

• The relative charge ratio between C and N atoms in amide bond acts as a key factor to determine peptide fragment efficiency in different charge states.

  Journal of the American Society for Mass Spectrometry 20101101

• Proteome-wide alterations in Escherichia coli translation rates upon anaerobiosis.

  Molecular & cellular proteomics : MCP 20101101

• Amino acid substitutions in the FXYD motif enhance phospholemman-induced modulation of cardiac L-type calcium channels.

  American journal of physiology. Cell physiology 20101101

• Effects of amino acid transport limitations on cultured hepatocytes.

  Biophysical chemistry 20101101

• An aminotransferase branch point connects purine catabolism to amino acid recycling.

  Nature chemical biology 20101101

• Taste genes associated with dental caries.

  Journal of dental research 20101101

• Brivanib, a novel dual VEGF-R2/bFGF-R inhibitor.

  Anticancer research 20101101

• [Association of PPARgamma2 Pro12Ala polymorphism and cognitive dysfunction in hypertension patients].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20101101

• A dual interface determines the recognition of RNA polymerase II by RNA capping enzyme.

  The Journal of biological chemistry 20101029

• Effect of bioengineering lacticin 3147 lanthionine bridges on specific activity and resistance to heat and proteases.

  Chemistry & biology 20101029

• Identification of metastable states in peptide's dynamics.

  The Journal of chemical physics 20101028

• Cardiac transplantation followed by dose-intensive melphalan and autologous stem-cell transplantation for light chain amyloidosis and heart failure.

  Transplantation 20101027

• Monocationic gold(III) Gly-L-His and L-Ala-L-His dipeptide complexes: crystal structures arising from solvent free and solvent-containing crystal formation and structural modifications tuned by counter-anions.

  Dalton transactions (Cambridge, England : 2003) 20101014

• Azido gauche effect on the backbone conformation of β-azidoalanine peptides.

  The journal of physical chemistry. B 20101014

• The kinetics of β-elimination of cystine and the formation of lanthionine in gliadin.

  Journal of agricultural and food chemistry 20101013

• Kinetic analysis of the bisubstrate cysteine desulfurase SufS from Bacillus subtilis.

  Biochemistry 20101012

• Proliferative and protective effects of SurR9-C84A on differentiated neural cells.

  Journal of neuroimmunology 20101008

• Solution NMR structure of the V27A drug resistant mutant of influenza A M2 channel.

  Biochemical and biophysical research communications 20101008

• Azidohomoalanine: a conformationally sensitive IR probe of protein folding, protein structure, and electrostatics.

  Angewandte Chemie (International ed. in English) 20101004

• Arthrobacter antarcticus sp. nov., isolated from an Antarctic marine sediment.

  International journal of systematic and evolutionary microbiology 20101001

• Angustibacter luteus gen. nov., sp. nov., isolated from subarctic forest soil.

  International journal of systematic and evolutionary microbiology 20101001

• Amplification of fibroblast growth factor receptor-1 in breast cancer and the effects of brivanib alaninate.

  Breast cancer research and treatment 20101001

• Analysis of alanine aminotransferase in various organs of soybean (Glycine max) and in dependence of different nitrogen fertilisers during hypoxic stress.

  Amino acids 20101001

• Hydrogen sulfide is an endogenous inhibitor of phosphodiesterase activity.

  Arteriosclerosis, thrombosis, and vascular biology 20101001

• Transport and degradation of pesticides in a biopurification system under variable flux Part II: A macrocosm study.

  Environmental pollution (Barking, Essex : 1987) 20101001

• Transport and degradation of pesticides in a biopurification system under variable flux, Part I: a microcosm study.

  Environmental pollution (Barking, Essex : 1987) 20101001

• The role of glucagon- and somatostatin-secreting cells in the regulation of insulin release and beta-cell function in heterotypic pseudoislets.

  Diabetes/metabolism research and reviews 20101001

• Fructose-1,6-bisphosphatase regulates glucose-stimulated insulin secretion of mouse pancreatic beta-cells.

  Endocrinology 20101001

• Tuning the serum persistence of human serum albumin domain III:diabody fusion proteins.

  Protein engineering, design & selection : PEDS 20101001

• Alzheimer's failure raises questions about disease-modifying strategies.

  Nature reviews. Drug discovery 20101001

• Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells.

  Cell cycle (Georgetown, Tex.) 20101001

• NerveCenter: Phase III Alzheimer trial halted: Search for therapeutic biomarkers continues.

  Annals of neurology 20101001

• Nuclear export and import of human hepatitis B virus capsid protein and particles.

  PLoS pathogens 20101001

• Alanine-glutamine dipeptide pretreatment protects rat renal function from small intestine ischemia-reperfusion injury.

  Minerva chirurgica 20101001

• Internal symmetry of basic elements in symmetry-based recoupling sequences under magic-angle spinning.

  The Journal of chemical physics 20100921

• Traceless ligation of cysteine peptides using selective deselenization.

  Angewandte Chemie (International ed. in English) 20100917

• Substituent effects on the reaction of beta-benzoylalanines with Pseudomonas fluorescens kynureninase.

  Biochemistry 20100914

• Nonpeptidic and potent small-molecule inhibitors of cIAP-1/2 and XIAP proteins.

  Journal of medicinal chemistry 20100909

• Photophysical properties of dipeptides containing substituted 3-(quinoxalin-6-yl) alanine. Spectroscopic studies and theoretical calculations.

  The journal of physical chemistry. A 20100909

• Alanine-to-threonine substitutions and amyloid diseases: butyrylcholinesterase as a case study.

  Chemico-biological interactions 20100906

• Congenital central hypoventilation syndrome: genotype-phenotype correlation in parents of affected children carrying a PHOX2B expansion mutation.

  Clinical genetics 20100901

• Altered sensitivity to excitotoxic cell death and glutamate receptor expression between two commonly studied mouse strains.

  Journal of neuroscience research 20100901

• Activation of a peroxisomal Pichia pastoris D-amino acid oxidase, which uses d-alanine as a preferred substrate, depends on pyruvate carboxylase.

  FEMS yeast research 20100901

• The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A.

  The Journal of clinical endocrinology and metabolism 20100901

• Association of the type 2 deiodinase Thr92Ala polymorphism with type 2 diabetes: case-control study and meta-analysis.

  European journal of endocrinology 20100901

• Expression and function of CD300 in NK cells.

  Journal of immunology (Baltimore, Md. : 1950) 20100901

• Field trial for evaluating the effects on honeybees of corn sown using Cruiser and Celest xl treated seeds.

  Bulletin of environmental contamination and toxicology 20100901

• Catching a glimpse of nucleosome dynamics.

  Cell cycle (Georgetown, Tex.) 20100901

• Safinamide in the treatment of Parkinson's disease.

  Expert opinion on pharmacotherapy 20100901

• Comparing position and force control for interactive molecular simulators with haptic feedback.

  Journal of molecular graphics & modelling 20100901

• Insulin sensitivity and liver glucose production in the rat are influenced by lifetime food restriction.

  Nutrition research (New York, N.Y.) 20100901

• Rebamipide-induced downregulation of phospholipase D inhibits inflammation and proliferation in gastric cancer cells.

  Experimental & molecular medicine 20100831

• Analysis of two polymorphisms of the manganese superoxide dismutase gene (Ile-58Thr and Ala-9Val) in patients with recurrent depressive disorder.

  Psychiatry research 20100830

• Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin.

  Molecular cell 20100827

• Structural analysis of WbpE from Pseudomonas aeruginosa PAO1: a nucleotide sugar aminotransferase involved in O-antigen assembly.

  Biochemistry 20100824

• On the identity of the radiation-induced stable alanine radical.

  Physical chemistry chemical physics : PCCP 20100821

• Self-assembly of a designed amyloid peptide containing the functional thienylalanine unit.

  The journal of physical chemistry. B 20100819

• ACS chemical neuroscience molecule spotlight on semagacestat (LY450139).

  ACS chemical neuroscience 20100818

• Polar groups in membrane channels: consequences of replacing alanines with serines in membrane-spanning gramicidin channels.

  Biochemistry 20100817

• Inhibitory role for D-alanylation of wall teichoic acid in activation of insect Toll pathway by peptidoglycan of Staphylococcus aureus.

  Journal of immunology (Baltimore, Md. : 1950) 20100815

• Emerging biological importance of central nervous system lanthionines.

  Molecules (Basel, Switzerland) 20100813

• Clinical presentations and skin denervation in amyloid neuropathy due to transthyretin Ala97Ser.

  Neurology 20100810

• Sonication-triggered instantaneous gel-to-gel transformation.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100809

• Structural and biochemical characterization of free methionine-R-sulfoxide reductase from Neisseria meningitidis.

  The Journal of biological chemistry 20100806

• K65R and K65A substitutions in HIV-1 reverse transcriptase enhance polymerase fidelity by decreasing both dNTP misinsertion and mispaired primer extension efficiencies.

  Journal of molecular biology 20100806

• Aza-1,2,3-triazole-3-alanine synthesis via copper-catalyzed 1,3-dipolar cycloaddition on aza-progargylglycine.

  The Journal of organic chemistry 20100806

• Protein-protein interactions between sigma(70) region 4 of RNA polymerase and Escherichia coli SoxS, a transcription activator that functions by the prerecruitment mechanism: evidence for 'off-DNA' and 'on-DNA' interactions.

  Journal of molecular biology 20100806

• Identification of surface residues on Niemann-Pick C2 essential for hydrophobic handoff of cholesterol to NPC1 in lysosomes.

  Cell metabolism 20100804

• Group III metabotropic glutamate receptors inhibit startle-mediating giant neurons in the caudal pontine reticular nucleus but do not mediate synaptic depression/short-term habituation of startle.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100804

• Vibrational and chiroptical spectroscopic characterization of gamma-turn model cyclic tetrapeptides containing two beta-Ala residues.

  Chirality 20100801

• A novel mutation of 5alpha-steroid reductase 2 deficiency (CD 65 ALA-PRO) with severe virilization defect in a Turkish family and difficulty in gender assignment.

  European journal of pediatrics 20100801

• The influences of water solvent on the structures and stabilities of Na+-AD conformers.

  Amino acids 20100801

• Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1beta secretion.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100801

• A chimera of green fluorescent protein with gelatinase binding and tumor targeting peptide.

  Protein expression and purification 20100801

• Obesity and type 2 diabetes in rats are associated with altered brain glycogen and amino-acid homeostasis.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100801

• Personalized cancer medicine: from molecular diagnostics to targeted therapy with natural products.

  Planta medica 20100801

• High-resolution nuclear magnetic resonance spectroscopic study of metabolites in the cerebrospinal fluid of patients with cervical myelopathy and lumbar radiculopathy.

  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20100801

• Crystal structure of the Apo form of D-Alanine:D-Alanine ligase (DDl) from Streptococcus mutans.

  Protein and peptide letters 20100801

• Mechanism of verapamil action on wild-type and slow-channel mutant human muscle acetylcholine receptor.

  Journal of neurochemistry 20100801

• Differential effects of Phe19 and Phe20 on fibril formation by amyloidogenic peptide A beta 16-22 (Ac-KLVFFAE-NH2).

  Proteins 20100801

• Computational alanine scanning with linear scaling semiempirical quantum mechanical methods.

  Proteins 20100801

• Alternatives to amino acid analysis for the purity control of pharmaceutical grade L-alanine.

  Journal of separation science 20100801

• Improved antimicrobial activity of h-lysozyme (107-115) by rational Ala substitution.

  Journal of peptide science : an official publication of the European Peptide Society 20100801

• TOMOCOMD-CAMPS and protein bilinear indices--novel bio-macromolecular descriptors for protein research: I. Predicting protein stability effects of a complete set of alanine substitutions in the Arc repressor.

  The FEBS journal 20100801

• RP-HPLC method with fluorescence detection for amino acids D/L ratio determination in fossil bones as a marker of DNA preservation.

  Journal of separation science 20100801

• Pressure-induced phase transitions in L-alanine, revisited.

  Acta crystallographica. Section B, Structural science 20100801

• A consecutive three alanine residue insertion mutant of human CAR: a novel CAR ligand screening system in HepG2 cells.

  The Journal of toxicological sciences 20100801

• Amyotrophic lateral sclerosis-frontotemporal lobar dementia in 3 families with p.Ala382Thr TARDBP mutations.

  Archives of neurology 20100801

• [A study of vibrational spectra of L-, D-, DL-alanine in terahertz Domain].

  Guang pu xue yu guang pu fen xi = Guang pu 20100801

• Involvement of non-NMDA receptors in central mediation of chemoreflexes in the shorthorn sculpin, Myoxocephalus scorpius.

  Respiratory physiology & neurobiology 20100731

• Role of H(2)O(2) on the kinetics of low-affinity high-capacity Na(+)-dependent alanine transport in SHR proximal tubular epithelial cells.

  Biochemical and biophysical research communications 20100730

• Hummer and Szabo-like potential of mean force estimator for bidirectional nonequilibrium pulling experiments/simulations.

  The journal of physical chemistry. B 20100729

• Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100728

• Merlin inhibits neurite outgrowth in the CNS.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100728

• Modulation of p-cyanophenylalanine fluorescence by amino acid side chains and rational design of fluorescence probes of alpha-helix formation.

  Biochemistry 20100727

• A disease-causing mutation in the active site of serine palmitoyltransferase causes catalytic promiscuity.

  The Journal of biological chemistry 20100723

• Residue-specific, real-time characterization of lag-phase species and fibril growth during amyloid formation: a combined fluorescence and IR study of p-cyanophenylalanine analogs of islet amyloid polypeptide.

  Journal of molecular biology 20100723

• Structure and conformational stability of protonated dialanine.

  The journal of physical chemistry. A 20100722

• ENDOR study on the dynamic properties of the first stable paramagnetic center in gamma-irradiated L-alanine crystals.

  The journal of physical chemistry. A 20100722

• A new tool for photoaffinity labeling studies: a partially constrained, benzophenone based, alpha-amino acid.

  Organic & biomolecular chemistry 20100721

• Modelling the influence of hydrogen bond network on chemical shielding tensors description. GIAO-DFT study of WALP23 transmembrane alpha-helix as a test case.

  Physical chemistry chemical physics : PCCP 20100714

• Efficient asymmetric organocatalytic formation of erythrose and threose under aqueous conditions.

  Chemical communications (Cambridge, England) 20100714

• Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site.

  Molecular cell 20100709

• Determination of equilibrium free energy from nonequilibrium work measurements.

  Physical chemistry chemical physics : PCCP 20100707

• Intramembranous valine linked to schizophrenia is required for neuregulin 1 regulation of the morphological development of cortical neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100707

• A pore residue of the KCNQ3 potassium M-channel subunit controls surface expression.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100707

• Force-induced lysozyme--HyHEL5 antibody dissociation and its analysis by means of a cooperative binding model.

  Biophysical journal 20100707

• Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts.

  The Journal of biological chemistry 20100702

• Generation and characterization of thymidine/D-alanine auxotrophic recombinant Lactococcus lactis subsp. lactis IL1403 expressing BmpB.

  Current microbiology 20100701

• Residue N84 of yeast cystathionine beta-synthase is a determinant of reaction specificity.

  Biochimica et biophysica acta 20100701

• Synthesis and electrochemical behaviour of beta-halodehydroamino acid derivatives.

  Amino acids 20100701

• Interactions between 1alpha,25(OH)2D3 and residues in the ligand-binding pocket of the vitamin D receptor: a correlated fragment molecular orbital study.

  The Journal of steroid biochemistry and molecular biology 20100701

• Separation of isomers L-alanine and sarcosine in urine by electrospray ionization and tandem differential mobility analysis-mass spectrometry.

  Journal of the American Society for Mass Spectrometry 20100701

• Production of hydrogen sulfide by two enzymes associated with biosynthesis of homocysteine and lanthionine in Fusobacterium nucleatum subsp. nucleatum ATCC 25586.

  Microbiology (Reading, England) 20100701

• Computational modelling of amino acid transfer interactions in the placenta.

  Experimental physiology 20100701

• UPLC-MS, HPLC-radiometric, and NMR-spectroscopic studies on the metabolic fate of 3-fluoro-[U-14C]-aniline in the bile-cannulated rat.

  Xenobiotica; the fate of foreign compounds in biological systems 20100701

• Vibrational and electronic characterisation of Staphylococcus aureus wall teichoic acids and relevant components in thin films.

  Analytical and bioanalytical chemistry 20100701

• In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons.

  Nature neuroscience 20100701

• Enantiodifferent proton exchange in alanine and asparagine in the presence of H(2)(17)O.

  Journal of molecular evolution 20100701

• [Progress in the development of anti-amyloid drugs for treatment of Alzheimer's disease.].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100701

• The energy dependence of lithium formate and alanine EPR dosimeters for medium energy x rays.

  Medical physics 20100701

• The pattern of human tau phosphorylation is the result of priming and feedback events in primary hippocampal neurons.

  Neuroscience 20100630

• Changes in extracellular pH affect glycine receptor channels expressed in HEK 293 cells.

  European journal of pharmacology 20100625

• Catalytic mechanism of heparinase II investigated by site-directed mutagenesis and the crystal structure with its substrate.

  The Journal of biological chemistry 20100625

• A molecular mechanism for Toll-IL-1 receptor domain-containing adaptor molecule-1-mediated IRF-3 activation.

  The Journal of biological chemistry 20100625

• Alanine scanning mutagenesis of HIV-1 gp41 heptad repeat 1: insight into the gp120-gp41 interaction.

  Biochemistry 20100622

• The identification of the two missing conformers of gas-phase alanine: a jet-cooled Raman spectroscopy study.

  Physical chemistry chemical physics : PCCP 20100621

• Engineering thrombin for selective specificity toward protein C and PAR1.

  The Journal of biological chemistry 20100618

• Purine substrate recognition by the nucleobase-ascorbate transporter signature motif in the YgfO xanthine permease: ASN-325 binds and ALA-323 senses substrate.

  The Journal of biological chemistry 20100618

• Severe familial ALS with a novel exon 4 mutation (L106F) in the SOD1 gene.

  Journal of the neurological sciences 20100615

• Dihydropyrimidinone positive modulation of delta-subunit-containing gamma-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant.

  Biochemistry 20100615

• DNA binding by the ETS protein TEL (ETV6) is regulated by autoinhibition and self-association.

  The Journal of biological chemistry 20100611

• Neutral penta- and hexacoordinate silicon(IV) complexes containing two bidentate ligands derived from the alpha-amino acids (S)-alanine, (S)-phenylalanine, and (S)-tert-leucine.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100611

• Role of juxtamembrane and transmembrane domains in the mechanism of natriuretic peptide receptor A activation.

  Biochemistry 20100608

• Study of 962 patients indicates progressive muscular atrophy is a form of ALS.

  Neurology 20100608

• Synthesis and biological characterization of argyrin F.

  ChemMedChem 20100607

• Electron attachment to amino acid clusters in helium nanodroplets: glycine, alanine, and serine.

  The Journal of chemical physics 20100607

• Characterization of the chemokine CXCL11-heparin interaction suggests two different affinities for glycosaminoglycans.

  The Journal of biological chemistry 20100604

• Manipulation of thiocillin variants by prepeptide gene replacement: structure, conformation, and activity of heterocycle substitution mutants.

  Journal of the American Chemical Society 20100602

• Cell-produced alpha-synuclein oligomers are targeted to, and impair, the 26S proteasome.

  Neurobiology of aging 20100601

• Georgenia halophila sp. nov., a halophilic actinobacterium isolated from a salt lake.

  International journal of systematic and evolutionary microbiology 20100601

• Chiral configuration of the hydration layers of D- and L-alanine in water implied from dilution calorimetry.

  Chirality 20100601

• Partitioning of acidic, basic and neutral amino acids into imidazolium-based ionic liquids.

  Amino acids 20100601

• Mechanical properties and osteocompatibility of novel biodegradable alanine based polyphosphazenes: Side group effects.

  Acta biomaterialia 20100601

• Ala54Thr polymorphism of fatty acid-binding protein 2 gene and fasting blood lipids: a meta-analysis.

  Atherosclerosis 20100601

• Irreversible inactivation of glutathione peroxidase 1 and reversible inactivation of peroxiredoxin II by H2O2 in red blood cells.

  Antioxidants & redox signaling 20100601

• Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus.

  Protein expression and purification 20100601

• Mice expressing the A53T mutant form of human alpha-synuclein exhibit hyperactivity and reduced anxiety-like behavior.

  Journal of neuroscience research 20100601

• Inter-individual variation in DNA damage and base excision repair in young, healthy non-smokers: effects of dietary supplementation and genotype.

  The British journal of nutrition 20100601

• Model peptide-based system used for the investigation of metal ions binding to histidine-containing polypeptides.

  Biopolymers 20100601

• Functional analysis of the missense APOC3 mutation Ala23Thr associated with human hypotriglyceridemia.

  Journal of lipid research 20100601

• Protective effect of rebamipide against celecoxib-induced gastric mucosal cell apoptosis.

  Biochemical pharmacology 20100601

• Role of Arg301 in substrate orientation and catalysis in subsite 2 of D-alanine:D-alanine (D-lactate) ligase from Leuconostoc mesenteroides: a molecular docking study.

  Journal of molecular graphics & modelling 20100601

• The type 2 deiodinase Thr92Ala polymorphism is associated with increased bone turnover and decreased femoral neck bone mineral density.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100601

• Engineering of sugar metabolism of Corynebacterium glutamicum for production of amino acid L-alanine under oxygen deprivation.

  Applied microbiology and biotechnology 20100601

• CD24 Ala57Val gene polymorphism and the risk of systemic lupus erythematosus.

  Tissue antigens 20100601

• Extracellular signal-regulated kinase and GEF-H1 mediate depolarization-induced Rho activation and paracellular permeability increase.

  American journal of physiology. Cell physiology 20100601

• Experimental treatment of oestrogen receptor (ER) positive breast cancer with tamoxifen and brivanib alaninate, a VEGFR-2/FGFR-1 kinase inhibitor: a potential clinical application of angiogenesis inhibitors.

  European journal of cancer (Oxford, England : 1990) 20100601

• Hydrogen-bonding induced cooperative effect on the energy transfer in helical polynorbornenes appended with porphyrin-containing amidic alanine linkers.

  Chemistry, an Asian journal 20100601

• A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity.

  Pharmacogenetics and genomics 20100601

• Peroxisome proliferator-activated receptor gamma polymorphism and periodontitis in pregnant Japanese women.

  Journal of periodontology 20100601

• The application of an aryl hydrazine linker prevents beta-elimination side products in the SPPS of C-terminal cysteine peptides.

  Journal of peptide science : an official publication of the European Peptide Society 20100601

• Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms.

  Genes & development 20100601

• Structure of the D-alanylgriseoluteic acid biosynthetic protein EhpF, an atypical member of the ANL superfamily of adenylating enzymes.

  Acta crystallographica. Section D, Biological crystallography 20100601

• Two polymorphs of safinamide, a selective and reversible inhibitor of monoamine oxidase B.

  Acta crystallographica. Section C, Crystal structure communications 20100601

• Rebamipide: a gastrointestinal protective drug with pleiotropic activities.

  Expert review of gastroenterology & hepatology 20100601

• Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones.

  Science (New York, N.Y.) 20100528

• Molecular dynamics simulations of Zn(2+) coordination in protein binding sites.

  The Journal of chemical physics 20100528

• Reversible hydrogen transfer between cysteine thiyl radical and glycine and alanine in model peptides: covalent H/D exchange, radical-radical reactions, and L- to D-Ala conversion.

  The journal of physical chemistry. B 20100520

• UV resonance Raman investigation of the conformations and lowest energy allowed electronic excited states of tri- and tetraalanine: charge transfer transitions.

  The journal of physical chemistry. B 20100520

• Plasma alanine levels increase in patients with schizophrenia as their clinical symptoms improve-Results from the Juntendo University Schizophrenia Projects (JUSP).

  Psychiatry research 20100515

• Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities.

  Journal of medicinal chemistry 20100513

• Molecular level characterization of the inorganic-bioorganic interface by solid state NMR: alanine on a silica surface, a case study.

  The journal of physical chemistry. B 20100513

• Single-molecule dynamics of gating in a neurotransmitter transporter homologue.

  Nature 20100513

• Structure and mechanism of receptor sharing by the IL-10R2 common chain.

  Structure (London, England : 1993) 20100512

• Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5'-monophosphates bearing a biodegradable protecting group.

  Organic & biomolecular chemistry 20100507

• Effects of L-alanine and inosine germinants on the elasticity of Bacillus anthracis spores.

  Langmuir : the ACS journal of surfaces and colloids 20100504

• Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras.

  Amino acids 20100501

• In vivo biosynthesis of an Ala-scan library based on the cyclic peptide SFTI-1.

  Amino acids 20100501

• Accurate free energy calculation along optimized paths.

  Journal of computational chemistry 20100501

• Curvature variation along the tropomyosin molecule.

  Journal of structural biology 20100501

• Co-inheritance of Hb Hershey [beta70(E14) Ala-->Gly] and Hb La Pommeraie [beta133(H11)Val-->Met] in a Sicilian subject.

  European journal of haematology 20100501

• Analysis of HmsH and its role in plague biofilm formation.

  Microbiology (Reading, England) 20100501

• G-protein beta3 subunit polymorphism and bleeding in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction 16 trial.

  Journal of thrombosis and haemostasis : JTH 20100501

• Phosphorylation of phosducin-like protein BDM-1 by protein kinase 2 (CK2) is required for virulence and G beta subunit stability in the fungal plant pathogen Cryphonectria parasitica.

  Molecular microbiology 20100501

• Microbial engineering of dehydro-amino acids and lanthionines in non-lantibiotic peptides.

  Antonie van Leeuwenhoek 20100501

• T(2) relaxation times of (13)C metabolites in a rat hepatocellular carcinoma model measured in vivo using (13)C-MRS of hyperpolarized [1-(13)C]pyruvate.

  NMR in biomedicine 20100501

• Separation of alpha- from beta-arylalanines by nickel nitrilotriacetate chromatography.

  Journal of separation science 20100501

• Age estimation by racemization method in teeth: application of aspartic acid, glutamate, and alanine.

  Journal of forensic sciences 20100501

• Correction/completion of the yeast actin, alanine scan alleles.

  Genetics 20100501

• Key proteolytic cleavage site and full-length form of DSPP.

  Journal of dental research 20100501

• A prodrug approach towards the development of tricyclic-based FBPase inhibitors.

  Bioorganic & medicinal chemistry letters 20100501

• Highly specific substrates of proteinase 3 containing 3-(2-benzoxazol-5-yl)-l-alanine and their application for detection of this enzyme in human serum.

  Analytical chemistry 20100501

• Characterization of bacterial spore germination using integrated phase contrast microscopy, Raman spectroscopy, and optical tweezers.

  Analytical chemistry 20100501

• First appraisal of brain pathology owing to A30P mutant alpha-synuclein.

  Annals of neurology 20100501

• Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans: insights into sulfidotrophic respiration and detoxification.

  Journal of molecular biology 20100430

• Metadynamics as a tool for mapping the conformational and free-energy space of peptides--the alanine dipeptide case study.

  The journal of physical chemistry. B 20100429

• Understanding microscopic binding of human microsomal prostaglandin E synthase-1 (mPGES-1) trimer with substrate PGH2 and cofactor GSH: insights from computational alanine scanning and site-directed mutagenesis.

  The journal of physical chemistry. B 20100429

• Direct chiral resolution of metalaxyl and metabolite metalaxyl acid in aged mobile phases: the role of trace water.

  Journal of agricultural and food chemistry 20100428

• Cysteine as a modulator residue in the active site of xenobiotic reductase A: a structural, thermodynamic and kinetic study.

  Journal of molecular biology 20100423

• Evidence that transcript cleavage is essential for RNA polymerase II transcription and cell viability.

  Molecular cell 20100423

• Relaxing the coenzyme specificity of 1,3-propanediol oxidoreductase from Klebsiella pneumoniae by rational design.

  Journal of biotechnology 20100415

• Anatomy of a red copper center: spectroscopic identification and reactivity of the copper centers of Bacillus subtilis Sco and its Cys-to-Ala variants.

  Journal of the American Chemical Society 20100414

• Towards peptide formation inside the channels of a new divinylaniline-bridged periodic mesoporous organosilica.

  Chemical communications (Cambridge, England) 20100414

• Replica exchange simulation method using temperature and solvent viscosity.

  The Journal of chemical physics 20100414

• Monopeptide versus monopeptoid: insights on structure and hydration of aqueous alanine and sarcosine via X-ray absorption spectroscopy.

  The journal of physical chemistry. B 20100408

• Liquid chromatography-tandem mass spectrometry for the determination of paclitaxel in rat plasma after intravenous administration of poly(L-glutamic acid)-alanine-paclitaxel conjugate.

  Journal of pharmaceutical and biomedical analysis 20100406

• The prevalence and clinical significance of inherited thrombophilic risk factors in patients with antiphospholipid syndrome.

  Journal of thrombosis and thrombolysis 20100401

• Microwave-assisted synthesis and characterization of optically active poly (ester-imide)s incorporating L-alanine.

  Amino acids 20100401

• Fluorescent analogues of the insect neuropeptide helicokinin I: synthesis, photophysical characterization and biological activity.

  Protein and peptide letters 20100401

• Helix propensities calculations for amino acids in alanine based peptides using Jarzynski's equality.

  Proteins 20100401

• Rescue of postcompaction-stage mouse embryo development from hypertonicity by amino acid transporter substrates that may function as organic osmolytes.

  Biology of reproduction 20100401

• Dissecting interactions between nucleosides and germination receptors in Bacillus cereus 569 spores.

  Microbiology (Reading, England) 20100401

• A single amino acid residue, Ala 105, confers 16alpha-hydroxylase activity to human cytochrome P450 17alpha-hydroxylase/17,20 lyase.

  The Journal of steroid biochemistry and molecular biology 20100401

• Disposition and metabolism of semagacestat, a {gamma}-secretase inhibitor, in humans.

  Drug metabolism and disposition: the biological fate of chemicals 20100401

• Birefringent physical gels of N-(4-n-alkyloxybenzoyl)-L-alanine amphiphiles in organic solvents: the role of hydrogen-bonding.

  Journal of colloid and interface science 20100401

• Major differences in the proportion of amino acid fiber types transmitting taste information from oral and extraoral regions in the channel catfish.

  Journal of neurophysiology 20100401

• AMPA receptors serum-dependently mediate GABAA receptor alpha1 and alpha6 subunit down-regulation in cultured mouse cerebellar granule cells.

  Neurochemistry international 20100401

• Anaerobic sulfatase-maturating enzyme--a mechanistic link with glycyl radical-activating enzymes?

  The FEBS journal 20100401

• Manganese superoxide dismutase (MnSOD) gene (Ala-9Val, Ile58Thr) polymorphism in patients with age-related macular degeneration (AMD).

  Medical science monitor : international medical journal of experimental and clinical research 20100401

• Rebamipide may be comparable to H2 receptor antagonist in healing iatrogenic gastric ulcers created by endoscopic mucosal resection: a prospective randomized pilot study.

  Journal of Korean medical science 20100401

• Poor outcome after liver transplantation for transthyretin amyloid neuropathy in a family with an Ala36Pro transthyretin mutation: case report.

  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20100401

• Structures and ice-binding faces of the alanine-rich type I antifreeze proteins.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20100401

• Total synthesis of the large non-ribosomal peptide polytheonamide B.

  Nature chemistry 20100401

• Molecular identification of carnosine synthase as ATP-grasp domain-containing protein 1 (ATPGD1).

  The Journal of biological chemistry 20100326

• Block effect of capsaicin on hERG potassium currents is enhanced by S6 mutation at Y652.

  European journal of pharmacology 20100325

• Importance of alanine at position 178 in proteorhodopsin for absorption of prevalent ambient light in the marine environment.

  Biochemistry 20100323

• Replacement of Ala by Aib improves structuration and biological stability in thymine-based alpha-nucleopeptides.

  Organic & biomolecular chemistry 20100321

• Binding and orientation of tricyclic antidepressants within the central substrate site of the human serotonin transporter.

  The Journal of biological chemistry 20100312

• Intra- and interdomain effects due to mutation of calcium-binding sites in calmodulin.

  The Journal of biological chemistry 20100312

• The p40/ARPC1 subunit of Arp2/3 complex performs multiple essential roles in WASp-regulated actin nucleation.

  The Journal of biological chemistry 20100312

• Comprehensive and cost-effective NMR spectroscopy of methyl groups in large proteins.

  Journal of the American Chemical Society 20100310

• Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Ralpha2.

  Structure (London, England : 1993) 20100310

• A residue in loop 9 of the beta2-subunit stabilizes the closed state of the GABAA receptor.

  The Journal of biological chemistry 20100305

• Current status of the AMOEBA polarizable force field.

  The journal of physical chemistry. B 20100304

• (S)-alpha-methyl,alpha-amino acids: a new stereocontrolled synthesis.

  Amino acids 20100301

• The intestinal absorption of a prodrug of the mGlu2/3 receptor agonist LY354740 is mediated by PEPT1: in situ rat intestinal perfusion studies.

  Journal of pharmaceutical sciences 20100301

• Effects of transgenic Pit-1 overexpression on calcium phosphate and bone metabolism.

  Journal of bone and mineral metabolism 20100301

• A new beta-chain haemoglobin variant with increased oxygen affinity: Hb Roma [beta115(g17)Ala-->Val].

  Biochimica et biophysica acta 20100301

• Clinical trial: rebamipide promotes gastric ulcer healing by proton pump inhibitor after endoscopic submucosal dissection--a randomized controlled study.

  Journal of gastroenterology 20100301

• Pharmacological activity of C10-substituted analogs of the high-affinity kainate receptor agonist dysiherbaine.

  Neuropharmacology 20100301

• Analysing overexpression of L-valine biosynthesis genes in pyruvate-dehydrogenase-deficient Corynebacterium glutamicum.

  Journal of industrial microbiology & biotechnology 20100301

• ATP13A2 G2236A variant is rare in patients with early-onset Parkinson's disease and familial Parkinson's disease from Mainland China.

  Parkinsonism & related disorders 20100301

• Role of loop 9 on the function of neuronal nicotinic receptors.

  Biochimica et biophysica acta 20100301

• The endogenous cannabinoid, anandamide, inhibits dopamine transporter function by a receptor-independent mechanism.

  Journal of neurochemistry 20100301

• Glycolysis and the tricarboxylic acid cycle are linked by alanine aminotransferase during hypoxia induced by waterlogging of Lotus japonicus.

  Plant physiology 20100301

• An improved procedure for the synthesis of dehydroamino acids and dehydropeptides from the carbonate derivatives of serine and threonine using tetrabutylammonium fluoride.

  Journal of peptide science : an official publication of the European Peptide Society 20100301

• Population description and its role in the interpretation of genetic association.

  Human genetics 20100301

• Commentary: healthy hair and protein loss.

  Journal of the American Academy of Dermatology 20100301

• Design, synthesis, hydrolysis kinetics and phamacodynamic profiles of histidine and alanine conjugates of aceclofenac.

  Acta pharmaceutica (Zagreb, Croatia) 20100301

• Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights.

  PLoS biology 20100301

• Antitumour response of a double mutant of staphylococcal enterotoxin C2 with the decreased affinity for MHC class II molecule.

  Scandinavian journal of immunology 20100301

• Structural characterization of teichoic acids from Lactobacillus brevis.

  Carbohydrate research 20100226

• Transport of the advanced glycation end products alanylpyrraline and pyrralylalanine by the human proton-coupled peptide transporter hPEPT1.

  Journal of agricultural and food chemistry 20100224

• Helix propensities of conformationally restricted amino acids. Non-natural substitutes for helix breaking proline and helix forming alanine.

  Organic & biomolecular chemistry 20100221

• Formal synthesis of belactosin A and hormaomycin via a diastereoselective intramolecular cyclopropanation of an alpha-nitro diazoester.

  Organic letters 20100219

• N-terminal acetylation of cellular proteins creates specific degradation signals.

  Science (New York, N.Y.) 20100219

• Acute in vivo genetic rescue demonstrates that phosphorylation of RIM1alpha serine 413 is not required for mossy fiber long-term potentiation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100217

• Molecular orientation and intermolecular interaction in alanine on Cu(001).

  Langmuir : the ACS journal of surfaces and colloids 20100216

• Effects of interdomain tether length and flexibility on the kinetics of intramolecular electron transfer in human sulfite oxidase.

  Biochemistry 20100216

• Behaviour of metalaxyl as copper oxychloride-metalaxyl commercial formulation vs. technical grade-metalaxyl in vineyards-devoted soils.

  Journal of hazardous materials 20100215

• Multiple novel classes of APRIL-specific receptor-blocking peptides isolated by phage display.

  Journal of molecular biology 20100212

• A series of alpha-amino acid ester prodrugs of camptothecin: in vitro hydrolysis and A549 human lung carcinoma cell cytotoxicity.

  Journal of medicinal chemistry 20100211

• Modification of loop 1 affects the nucleotide binding properties of Myo1c, the adaptation motor in the inner ear.

  Biochemistry 20100209

• Differential phospholipid binding of alpha-synuclein variants implicated in Parkinson's disease revealed by solution NMR spectroscopy.

  Biochemistry 20100209

• Activation of R235A mutant orotidine 5'-monophosphate decarboxylase by the guanidinium cation: effective molarity of the cationic side chain of Arg-235.

  Biochemistry 20100209

• Investigation of anticapsin biosynthesis reveals a four-enzyme pathway to tetrahydrotyrosine in Bacillus subtilis.

  Biochemistry 20100209

• Crystal structure of plant ferritin reveals a novel metal binding site that functions as a transit site for metal transfer in ferritin.

  The Journal of biological chemistry 20100205

• The preparation, germination properties and stability of superdormant spores of Bacillus cereus.

  Journal of applied microbiology 20100201

• Two new lipoaminoacids with complementary modes of action: new prospects to fight out against skin aging.

  International journal of cosmetic science 20100201

• Exploring kainate receptor pharmacology using molecular dynamics simulations.

  Neuropharmacology 20100201

• Manganese superoxide dismutase: effect of the ala16val polymorphism on protein, activity, and mRNA levels in human breast cancer cell lines and stably transfected mouse embryonic fibroblasts.

  Molecular and cellular biochemistry 20100201

• Dissipation of mefenoxam residue in watermelon and soil under field conditions.

  Bulletin of environmental contamination and toxicology 20100201

• Cytotoxic T lymphocyte antigen-4 Ala17 polymorphism is a genetic marker of autoimmune adrenal insufficiency: Italian association study and meta-analysis of European studies.

  European journal of endocrinology 20100201

• (1)H-(13)C Hetero-nuclear dipole-dipole couplings of methyl groups in stationary and magic angle spinning solid-state NMR experiments of peptides and proteins.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20100201

• (13)C Solid-state NMR chromatography by magic angle spinning (1)H T(1) relaxation ordered spectroscopy.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20100201

• 13C isotope effects on 1H chemical shifts: NMR spectral analysis of 13C-labelled D-glucose and some 13C-labelled amino acids.

  Magnetic resonance in chemistry : MRC 20100201

• Requirement for small side chain residues within the GxGD-motif of presenilin for gamma-secretase substrate cleavage.

  Journal of neurochemistry 20100201

• Interaction of maternal peroxisome proliferator-activated receptor gamma2 Pro12Ala polymorphism with fetal sex affects maternal glycemic control during pregnancy.

  Pharmacogenetics and genomics 20100201

• Desulfurization of cysteine-containing peptides resulting from sample preparation for protein characterization by mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20100201

• Sensitivity comparison of two L-alanine doped blends to different photon energies.

  Health physics 20100201

• Response of alanine and barium dithionate EPR dosimeters.

  Health physics 20100201

• Relevance of conserved lysine and arginine residues in transmembrane helices for the transport activity of organic anion transporting polypeptide 1B3.

  British journal of pharmacology 20100201

• The antiangiogenic activity in xenograft models of brivanib, a dual inhibitor of vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 kinases.

  Molecular cancer therapeutics 20100201

• A novel HLA-B allele, B*5535, was identified by sequence-based typing in a Chinese individual.

  Tissue antigens 20100201

• The TGL2 gene of Saccharomyces cerevisiae encodes an active acylglycerol lipase located in the mitochondria.

  The Journal of biological chemistry 20100129

• Sodium perchlorate effects on the helical stability of a mainly alanine peptide.

  Biophysical journal 20100120

• Control of impurities in L-aspartic acid and L-alanine by high-performance liquid chromatography coupled with a corona charged aerosol detector.

  Journal of chromatography. A 20100115

• Polymorphism (ALA16VAL) correlates with regional lymph node status in breast cancer.

  Cancer genetics and cytogenetics 20100115

• Purification and properties of cysteine protease from rhizomes of Curcuma longa (Linn.).

  Journal of the science of food and agriculture 20100115

• In-capillary derivatization and stacking electrophoretic analysis of gamma-aminobutyric acid and alanine in tea samples to redeem the detection after dilution to decrease matrix interference.

  Journal of agricultural and food chemistry 20100113

• Changeability of individual domains of an aminoacyl-tRNA in polymerization by the ribosome.

  FEBS letters 20100104

• Synthesis of orthogonally protected azahistidine: application to the synthesis of a GHK analogue.

  Amino acids 20100101

• Association of LT-alpha Ala252Gly gene polymorphism and the genetic predisposition of coronary heart disease in Chinese.

  Molecular biology reports 20100101

• IGFBP3 polymorphisms and risk of cancer: a meta-analysis.

  Molecular biology reports 20100101

• A liquid chromatography-tandem mass spectrometry assay for Marfey's derivatives of L-Ala, D-Ala, and D-Ala-D-Ala: application to the in vivo confirmation of alanine racemase as the target of cycloserine in Escherichia coli.

  Analytical biochemistry 20100101

• Methyl groups as probes of supra-molecular structure, dynamics and function.

  Journal of biomolecular NMR 20100101

• The PPAR-gamma Pro12Ala polymorphism associates with weight gain during GH-treatment in short children born small for gestational age.

  European journal of endocrinology 20100101

• A single amino acid controls the functional switch of human constitutive androstane receptor (CAR) 1 to the xenobiotic-sensitive splicing variant CAR3.

  The Journal of pharmacology and experimental therapeutics 20100101

• Snf1p regulates Gcn5p transcriptional activity by antagonizing Spt3p.

  Genetics 20100101

• The interferon-induced helicase IFIH1 Ala946Thr polymorphism is associated with type 1 diabetes in both the high-incidence Finnish and the medium-incidence Hungarian populations.

  Diabetologia 20100101

• Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.

  American journal of hypertension 20100101

• Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20100101

• Effects of supplementation with free glutamine and the dipeptide alanyl-glutamine on parameters of muscle damage and inflammation in rats submitted to prolonged exercise.

  Cell biochemistry and function 20100101

• Transport and degradation of metalaxyl and isoproturon in biopurification columns inoculated with pesticide-primed material.

  Chemosphere 20100101

• Treadmill gait analysis characterizes gait alterations in Parkinson's disease and amyotrophic lateral sclerosis mouse models.

  Journal of motor behavior 20100101

• Identification of a novel antitumor peptide based on the screening of an Ala-library derived from the LALF(32-51) region.

  Journal of peptide science : an official publication of the European Peptide Society 20100101

• Genetics of the glutamate-mediated methylamine utilization pathway in the facultative methylotrophic beta-proteobacterium Methyloversatilis universalis FAM5.

  Molecular microbiology 20100101

• The role of Bacillus anthracis germinant receptors in germination and virulence.

  Molecular microbiology 20100101

• Clonal expansion of the Belgian Phytophthora ramorum populations based on new microsatellite markers.

  Molecular ecology 20100101

• Double gaps along Shaker S4 demonstrate omega currents at three different closed states.

  Channels (Austin, Tex.) 20100101

• Using ex vivo proton magnetic resonance spectroscopy to reveal associations between biochemical and biological features of meningiomas.

  Neurosurgical focus 20100101

• Selective reduction of C=C double bonds in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of microcystins.

  European journal of mass spectrometry (Chichester, England) 20100101

• Troubleshooting in animal models of colitis: The use of a novel electrocautery model.

  Journal of pharmacological and toxicological methods 20100101

• Gamma/neutron dose evaluation using Fricke gel and alanine gel dosimeters to be applied in boron neutron capture therapy.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20100101

• Role of the gerP operon in germination and outgrowth of Bacillus anthracis spores.

  PloS one 20100101

• In response to 'a gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system'.

  Annals of neurology 20100101

• Mutagenesis analysis of the zinc-finger antiviral protein.

  Retrovirology 20100101

• Evaluation of the X-linked modifier loci for Leber hereditary optic neuropathy with the G11778A mutation in Chinese.

  Molecular vision 20100101

• Principles and determinants of G-protein coupling by the rhodopsin-like thyrotropin receptor.

  PloS one 20100101

• [A triple system water-urea-L-alpha-alanine. Thermodynamic properties and intermolecular interactions].

  Biofizika 20100101

• Synthesis of phospholipids containing polyunsaturated fatty acids by phospholipase A(2)-mediated esterification with food-compatible reagents.

  Journal of oleo science 20100101

• Blot-based detection of dehydroalanine-containing glutathione peroxidase with the use of biotin-conjugated cysteamine.

  Methods in enzymology 20100101

• Acute effect on the Aβ isoform pattern in CSF in response to γ-secretase modulator and inhibitor treatment in dogs.

  Journal of Alzheimer's disease : JAD 20100101

• Genetic structure and distribution of pythium aphanidermatum populations in Pennsylvania greenhouses based on analysis of AFLP and SSR markers.

  Mycologia 20100101

• Deoxysphingoid bases as plasma markers in diabetes mellitus.

  Lipids in health and disease 20100101

• [Oligonucleotides with peptide internucleotide linkage. A novel class of modified oligonucleotides].

  Bioorganicheskaia khimiia 20100101

• Selenocysteine, pyrrolysine, and the unique energy metabolism of methanogenic archaea.

  Archaea (Vancouver, B.C.) 20100101

• Proteomic characterization of vanA-containing Enterococcus recovered from Seagulls at the Berlengas Natural Reserve, W Portugal.

  Proteome science 20100101

• Polyelectrolyte multilayer films: A sponge for insulin?

  Bio-medical materials and engineering 20100101

• Fluorescence polarization analysis for revealing molecular mechanism of nucleotide-dependent phospholipid membrane binding of MinD adenosine 5'-triphosphate, adenosine triphosphatase.

  Biological & pharmaceutical bulletin 20100101

• Molecular characterization of glycopeptide-resistant enterococci from hospitals of the picardy region (france).

  International journal of microbiology 20100101

• Polymorphism Ala54Thr of fatty acid-binding protein 2: Allelic frequencies and influence on cardiovascular risk factors in a multicenter study of Castilla y Leon.

  Annals of nutrition & metabolism 20100101

• Metabolomic profiling of cellular responses to carvedilol enantiomers in vascular smooth muscle cells.

  PloS one 20100101

• Influence of the stability of a fused protein and its distance to the amyloidogenic segment on fibril formation.

  PloS one 20100101

• Content of free D-Ala and D-Glu in traditional Asian fermented seasonings.

  Journal of nutritional science and vitaminology 20100101

• Salt-specific stability of short and charged alanine-based alpha-helices.

  The journal of physical chemistry. B 20091231

• Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.

  Neuron 20091224

• Kinetic analysis of cysteine desulfurase CD0387 from Synechocystis sp. PCC 6803: formation of the persulfide intermediate.

  Biochemistry 20091222

• Raman and neutron scattering study of partially deuterated L-alanine: evidence of a solid-solid phase transition.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20091221

• Conformational effects of the non-natural alpha-methylserine on small peptides and glycopeptides.

  The Journal of organic chemistry 20091218

• Amphiphillic organic crystals.

  Journal of the American Chemical Society 20091216

• The heparin binding motif of endostatin mediates its interaction with receptor nucleolin.

  Biochemistry 20091215

• Dietary carotenoid-rich pequi oil reduces plasma lipid peroxidation and DNA damage in runners and evidence for an association with MnSOD genetic variant -Val9Ala.

  Genetics and molecular research : GMR 20091215

• Copper(II) and zinc(II) complexes with C-glycoside-pendant dipicolylamine (DPA)-amino acid conjugates.

  Dalton transactions (Cambridge, England : 2003) 20091214

• Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.

  Nature 20091210

• Thermodynamic aspects of coupled binding and folding of an intrinsically disordered protein: a computational alanine scanning study.

  Biochemistry 20091208

• Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death.

  Circulation research 20091204

• Isopeptide bonds in bacterial pili and their characterization by X-ray crystallography and mass spectrometry.

  Biopolymers 20091201

• Preclinical pharmacokinetics and in vitro metabolism of brivanib (BMS-540215), a potent VEGFR2 inhibitor and its alanine ester prodrug brivanib alaninate.

  Cancer chemotherapy and pharmacology 20091201

• GoLoco motif proteins binding to Galpha(i1): insights from molecular simulations.

  Journal of molecular modeling 20091201

• Ala54Thr polymorphism of fatty acid binding protein 2, role on insulin resistance and cardiovascular risk factors in presurgical morbid obesity patients.

  Obesity surgery 20091201

• An exonic insertion encodes an alanine stretch in porcine synapsin I.

  Biochemical genetics 20091201

• Impact of the PPAR-gamma2 Pro12Ala polymorphism and ACE inhibitor therapy on new-onset microalbuminuria in type 2 diabetes: evidence from BENEDICT.

  Diabetes 20091201

• Quantitative metabolic profiles of 2nd and 3rd trimester human amniotic fluid using (1)H HR-MAS spectroscopy.

  Magma (New York, N.Y.) 20091201

• Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A.

  Archives of biochemistry and biophysics 20091201

• Oligomeric interactions provide alternatives to direct steric modes of control of sugar kinase/actin/hsp70 superfamily functions by heterotropic allosteric effectors: inhibition of E. coli glycerol kinase.

  Archives of biochemistry and biophysics 20091201

• MYH9 related disease: a novel missense Ala95Asp mutation of the MYH9 gene.

  Platelets 20091201

• The contribution of key hydrophobic residues in ecotin to enzyme-inhibitor complex stability.

  Journal of enzyme inhibition and medicinal chemistry 20091201

• Physiological role of carbon dioxide in spore germination of Clostridium perfringens S40.

  Journal of bioscience and bioengineering 20091201

• HslVU ATP-dependent protease utilizes maximally six among twelve threonine active sites during proteolysis.

  The Journal of biological chemistry 20091127

• Metformin primarily decreases plasma glucose not by gluconeogenesis suppression but by activating glucose utilization in a non-obese type 2 diabetes Goto-Kakizaki rats.

  European journal of pharmacology 20091125

• Two lysine residues in the bacterial luciferase mobile loop stabilize reaction intermediates.

  The Journal of biological chemistry 20091120

• Identification of residues in the 558-loop of factor VIIIa A2 subunit that interact with factor IXa.

  The Journal of biological chemistry 20091120

• Identification of a new exosite involved in catalytic turnover by the streptokinase-plasmin activator complex during human plasminogen activation.

  The Journal of biological chemistry 20091120

• Role of Bacillus subtilis BacB in the synthesis of bacilysin.

  The Journal of biological chemistry 20091113

• Homochiral, helical metal-organic framework structures organized by strong, non-covalent pi-pi stacking interactions.

  Chemical communications (Cambridge, England) 20091107

• Inelastic neutron scattering and Raman spectroscopic investigation of L-alanine alaninium nitrate, a homologue of a ferroelectric material.

  Physical chemistry chemical physics : PCCP 20091107

• Chemical labeling strategy with (R)- and (S)-trifluoromethylalanine for solid state 19F NMR analysis of peptaibols in membranes.

  Journal of the American Chemical Society 20091104

• Reticulon-4A (Nogo-A) redistributes protein disulfide isomerase to protect mice from SOD1-dependent amyotrophic lateral sclerosis.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20091104

• Coverage dependence of the adsorption structure of alanine on Ge(100).

  Langmuir : the ACS journal of surfaces and colloids 20091103

• In vivo carbon-13 dynamic MRS and MRSI of normal and fasted rat liver with hyperpolarized 13C-pyruvate.

  Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20091101

• Mutational analysis of the GTP-binding motif of FlhF which regulates the number and placement of the polar flagellum in Vibrio alginolyticus.

  Journal of biochemistry 20091101

• SOD1 (A4V)-mediated ALS presenting with lower motor neuron facial diplegia and unilateral vocal cord paralysis.

  Muscle & nerve 20091101

• Cyclin D2 protein stability is regulated in pancreatic beta-cells.

  Molecular endocrinology (Baltimore, Md.) 20091101

• Imidazole-based erythrocyte markers of oxidative stress in preeclampsia--an NMR investigation.

  Reproductive sciences (Thousand Oaks, Calif.) 20091101

• Fragile X mental retardation protein is required for chemically-induced long-term potentiation of the hippocampus in adult mice.

  Journal of neurochemistry 20091101

• Metabolic fingerprinting of fresh lymphoma samples used to discriminate between follicular and diffuse large B-cell lymphomas.

  Experimental hematology 20091101

• Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma-2 gene on obesity risk and leptin levels in a Tunisian population.

  Clinical biochemistry 20091101

• The metabolic role of the legume endosperm: a noninvasive imaging study.

  Plant physiology 20091101

• Kinetic characterization and quaternary structure of glutamate racemase from the periodontal anaerobe Fusobacterium nucleatum.

  Archives of biochemistry and biophysics 20091101

• Rippling muscle disease and cardiomyopathy associated with a mutation in the CAV3 gene.

  Neuromuscular disorders : NMD 20091101

• Formation of chloroform during chlorination of alanine in drinking water.

  Chemosphere 20091101

• Effects of serotonergic agents on survival and hemolymph composition of the larval mosquito Aedes aegypti (Diptera: Culicidae, L.) in vivo: does serotonin regulate hemolymph acid-base homeostasis?

  The Journal of experimental biology 20091101

• Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster.

  PLoS biology 20091101

• Pharmacokinetics and bioequivalence of two formulations of rebamipide 100-mg tablets: a randomized, single-dose, two-period, two-sequence crossover study in healthy Korean male volunteers.

  Clinical therapeutics 20091101

• Toxicity of fungicides with different modes of action to Cladobotryum dendroides and Agaricus bisporus.

  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20091101

• Water and alanine: from puddles(32) to ponds(49).

  The journal of physical chemistry. B 20091029

• Isotope labeling studies on the origin of 3,4-hexanedione and 1,2-butanedione in an alanine/glucose model system.

  Journal of agricultural and food chemistry 20091028

• Effect of spent mushroom substrate amendment of vineyard soils on the behavior of fungicides: 2. Mobility of penconazole and metalaxyl in undisturbed soil cores.

  Journal of agricultural and food chemistry 20091028

• Through the looking glass, mechanistic insights from enantiomeric human defensins.

  The Journal of biological chemistry 20091016

• ATP-induced FliI hexamerization facilitates bacterial flagellar protein export.

  Biochemical and biophysical research communications 20091016

• Molecular consequences of genetic variations in the glutathione peroxidase 1 selenoenzyme.

  Cancer research 20091015

• Aza-beta3-cyclopeptides: a new way of controlling nitrogen chirality.

  Journal of the American Chemical Society 20091014

• Characterization of hydrophobic residue requirements for alpha-synuclein fibrillization.

  Biochemistry 20091013

• N-(1-carboxyethyl)alanine (alanopine), a new non-sugar component of lipopolysaccharides of Providencia and Proteus.

  Carbohydrate research 20091012

• Effects of phospholamban transmembrane mutants on the calcium affinity, maximal activity, and cooperativity of the sarcoplasmic reticulum calcium pump.

  Biochemistry 20091006

• Conformation of the phosphate D-alanine zwitterion in bacterial teichoic acid from nuclear magnetic resonance spectroscopy.

  Biochemistry 20091006

• [Occurrence of GRB10 (+11275G > A) polymorphism in Hungarian population and its relationship to glucose metabolism].

  Orvosi hetilap 20091004

• Magnitude of a conformational change in the glycine receptor beta1-beta2 loop is correlated with agonist efficacy.

  The Journal of biological chemistry 20091002

• The effects of alanine ingestion on metabolic responses to exercise in cyclists.

  Amino acids 20091001

• The importance of myocardial amino acids during ischemia and reperfusion in dilated left ventricle of patients with degenerative mitral valve disease.

  Molecular and cellular biochemistry 20091001

• The human G93A-superoxide dismutase-1 mutation, mitochondrial glutathione and apoptotic cell death.

  Neurochemical research 20091001

• +331G/A variant in the progesterone receptor gene, postmenopausal hormone use and risk of breast cancer.

  International journal of cancer 20091001

• The proline 12 alanine substitution in the PPARgamma2 gene is associated with increased extent of coronary artery disease in men.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20091001

• Effect of blood lactate-guided conditioning of horses with exercises of differing durations and intensities on heart rate and biochemical blood variables.

  Journal of animal science 20091001

• Polymorphism of Pro12Ala in the peroxisome proliferator-activated receptor gamma2 gene in Iranian diabetic and obese subjects.

  Metabolic syndrome and related disorders 20091001

• A novel approach for assessing protein synthesis in channel catfish, Ictalurus punctatus.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20091001

• The CDH1-160C>A polymorphism is a risk factor for colorectal cancer.

  International journal of cancer 20091001

• Probing the interaction of the amino acid alanine with the surface of ZnO(1010).

  Journal of colloid and interface science 20091001

• Mutant 5-hydroxytryptamine 1A receptor D116A is a receptor activated solely by synthetic ligands with a rich pharmacology.

  The Journal of pharmacology and experimental therapeutics 20091001

• Computation of energy interaction parameters as well as electric dipole intensity parameters for the absorption spectral study of the interaction of Pr(III) with l-phenylalanine, l-glycine, l-alanine and l-aspartic acid in the presence and absence of Ca2+ in organic solvents.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20091001

• The association of olanzapine-induced weight gain with peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism in patients with schizophrenia.

  DNA and cell biology 20091001

• Fundamental efforts toward the development of a therapeutic cocktail with a manifold ameliorative effect on hepatic ischemia/reperfusion injury.

  Microcirculation (New York, N.Y. : 1994) 20091001

• An extended AE-rich N-terminal trunk in secreted pineapple cystatin enhances inhibition of fruit bromelain and is posttranslationally removed during ripening.

  Plant physiology 20091001

• Charge-separation reactions of doubly-protonated peptides: effect of peptide chain length.

  Journal of the American Society for Mass Spectrometry 20091001

• On the charge partitioning between c and z fragments formed after electron-capture induced dissociation of charge-tagged Lys-Lys and Ala-Lys dipeptide dications.

  Journal of the American Society for Mass Spectrometry 20091001

• Cell-selective metabolic labeling of proteins.

  Nature chemical biology 20091001

• Interactions across the interface contribute the stability of homodimeric 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase.

  Archives of biochemistry and biophysics 20091001

• The proinflammatory action of microglial P2 receptors is enhanced in SOD1 models for amyotrophic lateral sclerosis.

  Journal of immunology (Baltimore, Md. : 1950) 20091001

• Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin.

  Nature cell biology 20091001

• Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation.

  Nature structural & molecular biology 20091001

• MyosinV controls PTEN function and neuronal cell size.

  Nature cell biology 20091001

• Structure of D-alanine-D-alanine ligase from Thermus thermophilus HB8: cumulative conformational change and enzyme-ligand interactions.

  Acta crystallographica. Section D, Biological crystallography 20091001

• A motor driving PTEN.

  Nature cell biology 20091001

• Assay of alanine:glyoxylate aminotransferase in human liver by its serine: glyoxylate aminotransferase activity.

  Biomedical research (Tokyo, Japan) 20091001

• Interpretation of p-cyanophenylalanine fluorescence in proteins in terms of solvent exposure and contribution of side-chain quenchers: a combined fluorescence, IR and molecular dynamics study.

  Biochemistry 20090929

• Towards enzyme-like enantioselectivity in the gas phase: conformational control of selectivity in chiral macrocyclic dimers.

  Chemical communications (Cambridge, England) 20090928

• Structural and molecular mechanism for autoprocessing of MARTX toxin of Vibrio cholerae at multiple sites.

  The Journal of biological chemistry 20090925

• Enantioselective acute toxicity and bioaccumulation of benalaxyl in earthworm (Eisenia fedtia).

  Journal of agricultural and food chemistry 20090923

• Facile formation of dehydroalanine from S-nitrosocysteines.

  Journal of the American Chemical Society 20090923

• The ALS-associated mutation G93A in human copper-zinc superoxide dismutase selectively destabilizes the remote metal binding region.

  Biochemistry 20090922

• Solvent-induced chirality inversion involving supramolecular helix transformation and color-tunable fluorescence of a C(6)-symmetric hexakis(phenylethynyl)benzene derivative.

  Organic & biomolecular chemistry 20090921

• Directionality and coordination of dehydration and ring formation during biosynthesis of the lantibiotic nisin.

  The Journal of biological chemistry 20090918

• Enhanced conversion of racemic alpha-arylalanines to (R)-beta-arylalanines by coupled racemase/aminomutase catalysis.

  The Journal of organic chemistry 20090918

• D-amino acids govern stationary phase cell wall remodeling in bacteria.

  Science (New York, N.Y.) 20090918

• Enantiospecific adsorption of amino acids on hydroxylated quartz (0001).

  Langmuir : the ACS journal of surfaces and colloids 20090915

• N-terminal aliphatic residues dictate the structure, stability, assembly, and small molecule binding of the coiled-coil region of cartilage oligomeric matrix protein.

  Biochemistry 20090915

• Preparation of hollow silica spheres with holes on the shells.

  Chemical communications (Cambridge, England) 20090914

• Mechanistic analysis of the blood group antigen-cleaving endo-beta-galactosidase from Clostridium perfringens.

  Biochemistry 20090908

• Theoretical and experimental studies on alpha/epsilon-hybrid peptides: design of a 14/12-helix from peptides with alternating (S)-C-linked carbo-epsilon-amino acid [(S)-epsilon-Caa((x))] and L-ala.

  The Journal of organic chemistry 20090904

• Post-translational modification and stability of low molecular weight cyclin E.

  Oncogene 20090903

• Effect of rebamipide on quality of peptic ulcer healing in rat.

  Digestive diseases and sciences 20090901

• Influence of ionization on the conformational preferences of peptide models. Ramachandran surfaces of N-formyl-glycine amide and N-formyl-alanine amide radical cations.

  Journal of computational chemistry 20090901

• Ab initio studies of receptor interactions with AMPA ((S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl) propionic acid) and kainic acid (2S-(2 alpha, 3 beta, 4 beta))-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid.

  Journal of molecular modeling 20090901

• Homology modeling of human alpha 1 beta 2 gamma 2 and house fly beta 3 GABA receptor channels and Surflex-docking of fipronil.

  Journal of molecular modeling 20090901

• Utilization of synthetic peptides to evaluate the importance of substrate interaction at the proteolytic site of Escherichia coli Lon protease.

  Biochimica et biophysica acta 20090901

• Fructose and glucose mediates enterotoxin production and anaerobic metabolism of Bacillus cereus ATCC14579(T).

  Journal of applied microbiology 20090901

• Release of endogenous amino acids from the hippocampus and brain stem from developing and adult mice in ischemia.

  Neurochemical research 20090901

• Overexpression of the malate-aspartate NADH shuttle member Aralar1 in the clonal beta-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism.

  Clinical science (London, England : 1979) 20090901

• Conformation dependence of the C(alpha)D(alpha) stretch mode in peptides. II. explicitly hydrated alanine peptide structures.

  Biopolymers 20090901

• Ala54Thr polymorphism of the fatty acid binding protein 2 gene and saturated fat intake in relation to lipid levels and insulin resistance: the Coronary Artery Risk Development in Young Adults (CARDIA) study.

  Metabolism: clinical and experimental 20090901

• Empirical estimation of the energetic contribution of individual interface residues in structures of protein-protein complexes.

  Journal of computer-aided molecular design 20090901

• Identification of a novel HLA-Cw*08 variant allele, Cw*0821.

  Tissue antigens 20090901

• Differential effects of gamma-secretase and BACE1 inhibition on brain Abeta levels in vitro and in vivo.

  Journal of neurochemistry 20090901

• The uterine placental bed Renin-Angiotensin system in normal and preeclamptic pregnancy.

  Endocrinology 20090901

• Toll-like receptor agonist induced changes in clonal rat BRIN-BD11 beta-cell insulin secretion and signal transduction.

  The Journal of endocrinology 20090901

• Probing the urea dependence of residual structure in denatured human alpha-lactalbumin.

  Journal of biomolecular NMR 20090901

• Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-beta (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators.

  Journal of neurochemistry 20090901

• Monitoring conformational dynamics with solid-state R 1rho experiments.

  Journal of biomolecular NMR 20090901

• Incorporating receptor flexibility in the molecular design of protein interfaces.

  Protein engineering, design & selection : PEDS 20090901

• Kinetic basis of partial agonism at NMDA receptors.

  Nature neuroscience 20090901

• Enhancing the utility of unnatural amino acid synthetases by manipulating broad substrate specificity.

  Molecular bioSystems 20090901

• Optimization of D-amino acid oxidase for low substrate concentrations--towards a cancer enzyme therapy.

  The FEBS journal 20090901

• ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271).

  Arthritis and rheumatism 20090901

• Mmp-20 and Klk4 cleavage site preferences for amelogenin sequences.

  Journal of dental research 20090901

• Effect of rebamipide on gastric ulcer healing caused by Helicobacter pylori and/or NSAIDs or non NSAIDs-non H. pylori.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20090901

• Self-assembling peptide nanofiber scaffolds, platelet-rich plasma, and mesenchymal stem cells for injectable bone regeneration with tissue engineering.

  The Journal of craniofacial surgery 20090901

• Antral ulcers induced by alendronate, a nitrogen-containing biphophonate, in rat stomachs - prophylactic effect of rebamipide.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20090901

• Drug design, in vitro pharmacology, and structure-activity relationships of 3-acylamino-2-aminopropionic acid derivatives, a novel class of partial agonists at the glycine site on the N-methyl-D-aspartate (NMDA) receptor complex.

  Journal of medicinal chemistry 20090827

• PACS-1 mediates phosphorylation-dependent ciliary trafficking of the cyclic-nucleotide-gated channel in olfactory sensory neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090826

• Synthesis of thiourea-tethered C-glycosyl amino acids via isothiocyanate-amine coupling.

  Organic & biomolecular chemistry 20090821

• Self-trapped vibrational states in synthetic beta-sheet helices.

  Chemical communications (Cambridge, England) 20090821

• Multiple roles of the active site lysine of Dopa decarboxylase.

  Archives of biochemistry and biophysics 20090815

• Determination of D-serine and D-alanine in the tissues and physiological fluids of mice with various D-amino-acid oxidase activities using two-dimensional high-performance liquid chromatography with fluorescence detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090815

• Type 2 deiodinase Thr92Ala polymorphism impact on clinical course and myocardial remodeling in patients with Graves' disease.

  Cell cycle (Georgetown, Tex.) 20090815

• Relative contributions of cystathionine beta-synthase and gamma-cystathionase to H2S biogenesis via alternative trans-sulfuration reactions.

  The Journal of biological chemistry 20090814

• The elucidation of the structure of Thermotoga maritima peptidoglycan reveals two novel types of cross-link.

  The Journal of biological chemistry 20090814

• The effect of the NH2 substituent on NH3: hydrazine as an alternative for ammonia in hydrogen release in the presence of boranes and alanes.

  Physical chemistry chemical physics : PCCP 20090814

• Site-specific N- and C-terminal labeling of a single polypeptide using sortases of different specificity.

  Journal of the American Chemical Society 20090812

• Modeling an electronic conductor based on natural peptide sequences.

  Biomacromolecules 20090810

• Phosphorylation-dependent autoinhibition of myosin light chain phosphatase accounts for Ca2+ sensitization force of smooth muscle contraction.

  The Journal of biological chemistry 20090807

• Selective arginines are important for the antibacterial activity and host cell interaction of human alpha-defensin 5.

  FEBS letters 20090806

• QTAIM study of an alpha-helix hydrogen bond network.

  The journal of physical chemistry. B 20090806

• Biochemical analysis of oligomerization of expanded polyalanine repeat proteins.

  Journal of neuroscience research 20090801

• Involvement of histidines 11, 15 and 19 in the binding of zinc to the fusogenic H5WYG peptide.

  Journal of mass spectrometry : JMS 20090801

• Functional importance of a structurally distinct homodimeric complex of the family B G protein-coupled secretin receptor.

  Molecular pharmacology 20090801

• Five amino acids in the innermost cavity of the substrate binding cleft of organic cation transporter 1 interact with extracellular and intracellular corticosterone.

  Molecular pharmacology 20090801

• Evaluation of toxic and interactive toxic effects of three agrochemicals and copper using a battery of microbiotests.

  The Science of the total environment 20090801

• Continued development of an empirical function for predicting and rationalizing protein-protein binding affinities.

  Biophysical chemistry 20090801

• Chemical analysis of late stages of pheomelanogenesis: conversion of dihydrobenzothiazine to a benzothiazole structure.

  Pigment cell & melanoma research 20090801

• Seeing red: pheomelanin synthesis uncovered.

  Pigment cell & melanoma research 20090801

• Amino acids in the rat intestinal lumen regulate their own absorption from a distant intestinal site.

  American journal of physiology. Gastrointestinal and liver physiology 20090801

• Aplysia cys-loop glutamate-gated chloride channels reveal convergent evolution of ligand specificity.

  Journal of molecular evolution 20090801

• Comparative effect of N-substituted dehydroamino acids and alpha-tocopherol on rat liver lipid peroxidation activities.

  Journal of enzyme inhibition and medicinal chemistry 20090801

• Synthesis and evaluation of new endomorphin analogues modified at the Pro(2) residue.

  Bioorganic & medicinal chemistry letters 20090801

• Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli.

  Nature chemical biology 20090801

• Transferability and reproducibility in electron-density studies--bond-topological and atomic properties of tripeptides of the type L-alanyl-X-L-alanine.

  Acta crystallographica. Section B, Structural science 20090801

• Oral administration of Excitin-1 (beta-alanyl-L-leucine) alters behavior and brain monoamine and amino acid concentrations in rats.

  Nutritional neuroscience 20090801

• Nutrient uptake by marine invertebrates: cloning and functional analysis of amino acid transporter genes in developing sea urchins (Strongylocentrotus purpuratus).

  The Biological bulletin 20090801

• Disinfection byproduct formation and fractionation behavior of natural organic matter surrogates.

  Environmental science & technology 20090801

• Adsorption of chlorpyrifos, penconazole and metalaxyl from aqueous solution by modified clays.

  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20090801

• The biological activity of the prototypic cyclotide kalata b1 is modulated by the formation of multimeric pores.

  The Journal of biological chemistry 20090731

• Enterocin C, a class IIb bacteriocin produced by E. faecalis C901, a strain isolated from human colostrum.

  International journal of food microbiology 20090731

• Unravelling the conformational dynamics of the aqueous alanine dipeptide with first-principle molecular dynamics.

  The journal of physical chemistry. B 20090730

• The effects of group III mGluR ligands on pentylenetetrazol-induced kindling of seizures and hippocampal amino acids concentration.

  Brain research 20090728

• Ala scanning of the inhibitory region of cardiac troponin I.

  The Journal of biological chemistry 20090724

• Calculation of free-energy differences by confinement simulations. Application to peptide conformers.

  The journal of physical chemistry. B 20090723

• Intra- and intermolecular effects on 1H chemical shifts in a silk model Peptide determined by high-field solid state 1H NMR and empirical calculations.

  The journal of physical chemistry. B 20090723

• Transport of free and peptide-bound pyrraline at intestinal and renal epithelial cells.

  Journal of agricultural and food chemistry 20090722

• Network of hydrogen bonds in Pro-Ala-Pro and Pro-Phe-Pro diamides: a first principles study of Ala-->Phe point mutation in proline environment.

  The Journal of chemical physics 20090721

• Inoculation of sugarcane with Pantoea sp. increases amino acid contents in shoot tissues; serine, alanine, glutamine and asparagine permit concomitantly ammonium excretion and nitrogenase activity of the bacterium.

  Journal of plant physiology 20090715

• Elucidation of the disulfide bridge pattern of the recombinant human growth and differentiation factor 5 dimer and the interchain Cys/Ala mutant monomer.

  Analytical biochemistry 20090715

• Solvation and hydrogen bonding in alanine- and glycine-containing dipeptides probed using solution- and solid-state NMR spectroscopy.

  Journal of the American Chemical Society 20090715

• Amidation of bioactive peptides: the structure of the lyase domain of the amidating enzyme.

  Structure (London, England : 1993) 20090715

• Primary steps in the reaction of OH radicals with amino acids at low temperatures in Laval nozzle expansions: perspectives from experiment and theory.

  The journal of physical chemistry. A 20090702

• Rebamipide, a cytoprotective drug, increases gastric mucus secretion in human: evaluations with endoscopic gastrin test.

  Digestive diseases and sciences 20090701

• Conformational preferences of a short Aib/Ala-based water-soluble peptide as a function of temperature.

  Proteins 20090701

• Determination of metalaxyl and identification of adjuvants in wettable powder pesticide technical formulas.

  Analytical and bioanalytical chemistry 20090701

• Toxicity of triclosan, penconazole and metalaxyl on Caulobacter crescentus and a freshwater microbial community as assessed by flow cytometry.

  Environmental microbiology 20090701

• Effects of streptozotocin-induced diabetes in domestic pigs with focus on the amino acid metabolism.

  Laboratory animals 20090701

• Functional characterization of the thylakoid Ndh complex phosphorylation by site-directed mutations in the ndhF gene.

  Biochimica et biophysica acta 20090701

• Reversed-phase liquid chromatographic determination of enantiomers of atenolol in rat plasma using derivatization with Marfey's reagent.

  Biomedical chromatography : BMC 20090701

• Identification and quantitation of newly synthesized proteins in Escherichia coli by enrichment of azidohomoalanine-labeled peptides with diagonal chromatography.

  Molecular & cellular proteomics : MCP 20090701

• A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system.

  Annals of neurology 20090701

• Monte Carlo simulation of the response of ESR dosimeters added with gadolinium exposed to thermal, epithermal and fast neutrons.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20090701

• Selective enrichment of azide-containing peptides from complex mixtures.

  Journal of proteome research 20090701

• Alanine screening of the intracellular loops of the human bradykinin B receptor--effects on receptor maintenance, G protein activation and internalization.

  The FEBS journal 20090701

• Construction and functional analyses of a comprehensive sigma54 site-directed mutant library using alanine-cysteine mutagenesis.

  Nucleic acids research 20090701

• Alanine-2 carbonyl is an oxygen ligand in Cu2+ coordination of Alzheimer's disease amyloid-beta peptide--relevance to N-terminally truncated forms.

  Journal of the American Chemical Society 20090701

• Phosphorylation of ATXN1 at Ser776 in the cerebellum.

  Journal of neurochemistry 20090701

• Development of semagacestat (LY450139), a functional gamma-secretase inhibitor, for the treatment of Alzheimer's disease.

  Expert opinion on pharmacotherapy 20090701

• Alanine substitutions of noncysteine residues in the cysteine-stabilized alphabeta motif.

  Protein science : a publication of the Protein Society 20090701

• First observation of natural circular dichroism spectra in the extreme ultraviolet region using a polarizing undulator-based optical system and its polarization characteristics.

  Journal of synchrotron radiation 20090701

• Semagacestat, a gamma-secretase inhibitor for the potential treatment of Alzheimer's disease.

  Current opinion in investigational drugs (London, England : 2000) 20090701

• [Study on the relationship between FABP2 Ala54Thr polymorphism and the risk of non-alcoholic fatty liver diseases].

  Wei sheng yan jiu = Journal of hygiene research 20090701

• Pro12Ala polymorphism in PPARgamma2 associated with depression in Chinese nonagenarians/centenarians.

  Archives of medical research 20090701

• Interplay of sequence, conformation, and binding at the Peptide-titania interface as mediated by water.

  ACS applied materials & interfaces 20090701

• Alanine: then there was water.

  The journal of physical chemistry. B 20090625

• Mechanistic investigations of anaerobic sulfatase-maturating enzyme: direct Cbeta H-atom abstraction catalyzed by a radical AdoMet enzyme.

  Journal of the American Chemical Society 20090624

• Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides.

  Chemical communications (Cambridge, England) 20090621

• Simultaneous escaping of explicit and hidden free energy barriers: application of the orthogonal space random walk strategy in generalized ensemble based conformational sampling.

  The Journal of chemical physics 20090621

• Car-Parrinello density matrix search with a first principles fictitious electron mass method for electronic wave function optimization.

  The Journal of chemical physics 20090621

• Amino acid-based synthesis of trifluoromethylalkene dipeptide isosteres by alcohol-assisted nucleophilic trifluoromethylation and organozinc-copper-mediated S(N)2' alkylation.

  The Journal of organic chemistry 20090619

• Adrenaline and reactive oxygen species elicit proteome and energetic metabolism modifications in freshly isolated rat cardiomyocytes.

  Toxicology 20090616

• Identification of computational hot spots in protein interfaces: combining solvent accessibility and inter-residue potentials improves the accuracy.

  Bioinformatics (Oxford, England) 20090615

• Enantioselective recognition of alanine in solution with modified gold electrodes using chiral PAMAM dendrimers G4.0.

  Talanta 20090615

• Kinetics and reaction coordinate for the isomerization of alanine dipeptide by a forward flux sampling protocol.

  The Journal of chemical physics 20090614

• Alanine scanning of the S6 segment reveals a unique and cAMP-sensitive association between the pore and voltage-dependent opening in HCN channels.

  The Journal of biological chemistry 20090605

• Multifunctional role of His159in the catalytic reaction of serine palmitoyltransferase.

  The Journal of biological chemistry 20090605

• Regulation of microtubule dynamic instability in vitro by differentially phosphorylated stathmin.

  The Journal of biological chemistry 20090605

• Fine mapping of the sequence requirements for binding of beta-lactamase inhibitory protein (BLIP) to TEM-1 beta-lactamase using a genetic screen for BLIP function.

  Journal of molecular biology 20090605

• Novel amino-acid-based polymer/multi-walled carbon nanotube bio-nanocomposites: highly water dispersible carbon nanotubes decorated with gold nanoparticles.

  Nanotechnology 20090603

• A novel mutation Ala57Val of the ELA2 gene in a Korean boy with severe congenital neutropenia.

  Annals of hematology 20090601

• Lincomycin, rational selection of high producing strain and improved fermentation by amino acids supplementation.

  Bioprocess and biosystems engineering 20090601

• Estimation on the intramolecular 10-membered ring N-H...O=C hydrogen-bonding energies in glycine and alanine peptides.

  Journal of computational chemistry 20090601

• Quantitative structure activity relationship of IA3-like peptides as aspartic proteinase inhibitors.

  Proteins 20090601

• Effect of pressure on helix-coil transition of an alanine-based peptide: an FTIR study.

  Proteins 20090601

• G protein inactive and active forms investigated by simulation methods.

  Proteins 20090601

• Functional study of cytoplasmic loops of human skeletal muscle chloride channel, hClC-1.

  The international journal of biochemistry & cell biology 20090601

• Detachment of sprayed colloidal copper oxychloride-metalaxyl fungicides by a shallow water flow.

  Pest management science 20090601

• Rationally designed dehydroalanine (DeltaAla)-containing peptides inhibit amyloid-beta (Abeta) peptide aggregation.

  Biopolymers 20090601

• Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser.

  Drug metabolism and disposition: the biological fate of chemicals 20090601

• Higher order multipole moments for molecular dynamics simulations.

  Journal of molecular modeling 20090601

• The effect of pre-coating human bone marrow stromal cells with hydroxyapatite/amino acid nanoconjugates on osteogenesis.

  Biomaterials 20090601

• Disruption of D-alanyl esterification of Staphylococcus aureus cell wall teichoic acid by the {beta}-lactam resistance modifier (-)-epicatechin gallate.

  The Journal of antimicrobial chemotherapy 20090601

• Activation of iGluR5 kainate receptors inhibits neurogenic dural vasodilatation in an animal model of trigeminovascular activation.

  British journal of pharmacology 20090601

• MQ-PGSTE: a new multi-quantum STE-based PGSE NMR sequence.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20090601

• 4'-Epidoxorubicin to re-explore anthracycline degradation in cardiomyocytes.

  Chemical research in toxicology 20090601

• The evolutionarily conserved residue A653 plays a key role in HERG channel closing.

  The Journal of physiology 20090601

• The T-lock: automated compensation of radio-frequency induced sample heating.

  Journal of biomolecular NMR 20090601

• Targeting DNA repair in chronic lymphocytic leukemia cells with a novel acyclic nucleotide analogue, GS-9219.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090601

• Mutagenic analysis of putative domain II and surface residues in mosquitocidal Bacillus thuringiensis Cry19Aa toxin.

  FEMS microbiology letters 20090601

• Effective synthesis of optically active trifluoromethyldiazirinyl homophenylalanine and aroylalanine derivatives with the Friedel-Crafts reaction in triflic acid.

  Bioscience, biotechnology, and biochemistry 20090601

• Circadian variations of gastrointestinal mucosal damage detected with transnasal endoscopy in apparently healthy subjects treated with low-dose aspirin (ASA) for a short period.

  Journal of atherosclerosis and thrombosis 20090601

• Effect of foliar feeding on nitrogen assimilation in alfalfa plants at insufficient molybdenum supply.

  Acta biologica Hungarica 20090601

• Dynamics of hydration water in proteins.

  General physiology and biophysics 20090601

• Electrophysiological characterization of electrolyte and nutrient transport across the small intestine in horses.

  Journal of animal physiology and animal nutrition 20090601

• The membrane-binding motif of the chloroplast signal recognition particle receptor (cpFtsY) regulates GTPase activity.

  The Journal of biological chemistry 20090529

• gamma-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice.

  Biochemical and biophysical research communications 20090529

• The structure of the ankyrin-binding site of beta-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties.

  Blood 20090528

• Structure and orientation of small molecules dissolved in the liquid crystalline phases of CsPFO/water system by multinuclear NMR.

  Physical chemistry chemical physics : PCCP 20090528

• Free energies and forces in helix-coil transition of homopolypeptides under stretching.

  Physical chemistry chemical physics : PCCP 20090528

• Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C.

  Neuron 20090528

• Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527

• Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine.

  The Journal of biological chemistry 20090522

• Mechanism of interaction between the general anesthetic halothane and a model ion channel protein, II: Fluorescence and vibrational spectroscopy using a cyanophenylalanine probe.

  Biophysical journal 20090520

• Mechanism of interaction between the general anesthetic halothane and a model ion channel protein, III: Molecular dynamics simulation incorporating a cyanophenylalanine spectroscopic probe.

  Biophysical journal 20090520

• Reaction mechanism of glutamate carboxypeptidase II revealed by mutagenesis, X-ray crystallography, and computational methods.

  Biochemistry 20090519

• Mutational analysis of Mycobacterium UvrD1 identifies functional groups required for ATP hydrolysis, DNA unwinding, and chemomechanical coupling.

  Biochemistry 20090519

• A stable and selective electrochemical biosensor for the liver enzyme alanine aminotransferase (ALT).

  Biosensors & bioelectronics 20090515

• Elastic and inelastic light scattering from single bacterial spores in an optical trap allows the monitoring of spore germination dynamics.

  Analytical chemistry 20090515

• Assessment of GS-9219 in a pet dog model of non-Hodgkin's lymphoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090515

• Amide I bands of terminally blocked alanine in solutions investigated by infrared spectroscopy and density functional theory calculation: hydrogen-bonding interactions and solvent effects.

  The journal of physical chemistry. B 20090514

• Mechanisms of antagonism of the GluR2 AMPA receptor: structure and dynamics of the complex of two willardiine antagonists with the glutamate binding domain.

  Biochemistry 20090512

• A conserved hydrogen-bond network stabilizes the structure of Beta class glutathione S-transferases.

  Biochemical and biophysical research communications 20090508

• A dynamic magic angle spinning NMR study of the local mobility of alanine in an aqueous environment at the inner surface of mesoporous materials.

  The journal of physical chemistry. B 20090507

• In vivo dosimetry in the urethra using alanine/ESR during (192)Ir HDR brachytherapy of prostate cancer--a phantom study.

  Physics in medicine and biology 20090507

• (51)V solid-state NMR and density functional theory studies of eight-coordinate non-oxo vanadium complexes: oxidized amavadin.

  Dalton transactions (Cambridge, England : 2003) 20090507

• TIGER2: an improved algorithm for temperature intervals with global exchange of replicas.

  The Journal of chemical physics 20090507

• Pyridylalanine (pal)-peptide catalyzed enantioselective allenoate additions to N-acyl imines.

  Journal of the American Chemical Society 20090506

• Peptide derivation of poorly absorbable drug allows intestinal absorption via peptide transporter.

  Journal of pharmaceutical sciences 20090501

• Impact of 789Ala/Ala genotype on quantitative type of von Willebrand disease.

  Annals of hematology 20090501

• The Val762Ala polymorphism in the poly(ADP-ribose) polymerase-1 gene is not associated with susceptibility in Turkish rheumatoid arthritis patients.

  Rheumatology international 20090501

• Growth and spectroscopic characterization of a new organic nonlinear optical crystal: L-alaninium succinate.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090501

• Characterization of alkali induced formation of lanthionine, trisulfides, and tetrasulfides from peptide disulfides using negative ion mass spectrometry.

  Journal of the American Society for Mass Spectrometry 20090501

• Intramolecular electron transfer processes in Cu(B)-deficient cytochrome bo studied by pulse radiolysis.

  Journal of biochemistry 20090501

• PPAR gamma variant influences angiographic outcome and 10-year cardiovascular risk in male symptomatic coronary artery disease patients.

  Diabetes care 20090501

• The effect of hyperpolarized tracer concentration on myocardial uptake and metabolism.

  Magnetic resonance in medicine 20090501

• Identification of serine/threonine kinase substrates in the human pathogen group B streptococcus.

  Journal of proteome research 20090501

• Non-operative management of right side thoracoabdominal penetrating injuries--the value of testing chest tube effluent for bile.

  Injury 20090501

• Impairment of D-alanine biosynthesis in Mycobacterium smegmatis determines decreased intracellular survival in human macrophages.

  Microbiology (Reading, England) 20090501

• The Ala54Thr polymorphism in the fatty acid-binding protein 2 gene leads to higher food intake in Japanese women.

  Molecular psychiatry 20090501

• Contribution of individual histidines to the global stability of human prolactin.

  Protein science : a publication of the Protein Society 20090501

• Synthesis of some new spiropyranoquinolines and evaluation of their free radical scavenging activity.

  Chemical & pharmaceutical bulletin 20090501

• A novel limb in the osmoregulatory network of Methanosarcina mazei Gö1: N(epsilon)-acetyl-beta-lysine can be substituted by glutamate and alanine.

  Environmental microbiology 20090501

• Do N-terminal nucleophile hydrolases indeed have a single amino acid catalytic center?

  The FEBS journal 20090501

• [Rebamipide inhibited expression of TLR4 and TNF-alpha release in pulmonary epithelial cell line A549 induced by lipopolysaccharide].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20090501

• Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease.

  Journal of neuropathology and experimental neurology 20090501

• [The role of NO resulted from neuronal nitric oxide synthase in the metabotropic glutamate receptor2/3 mediated-brain ischemic tolerance].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20090501

• Energy landscapes associated with the self-aggregation of an alanine-based oligopeptide (AAKA)4.

  The journal of physical chemistry. B 20090430

• H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia.

  The Journal of biological chemistry 20090424

• CASK point mutation regulates protein-protein interactions and NR2b promoter activity.

  Biochemical and biophysical research communications 20090424

• Mimicking Ndc80 phosphorylation triggers spindle assembly checkpoint signalling.

  The EMBO journal 20090422

• Toward homogeneous erythropoietin: chemical synthesis of the Ala1-Gly28 glycopeptide domain by 'alanine' ligation.

  Journal of the American Chemical Society 20090422

• Crystal structures of intermediates in the nitroalkane oxidase reaction.

  Biochemistry 20090421

• New fluorinated peptidomimetics through tandem aza-michael addition to alpha-trifluoromethyl acrylamide acceptors: synthesis and conformational study in solid state and solution.

  The Journal of organic chemistry 20090417

• Effect of a carboxyl group on the chemiluminescent reaction of tris(2,2'-bipyridine)ruthenium(III) with aliphatic amines.

  Talanta 20090415

• A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration.

  Cell cycle (Georgetown, Tex.) 20090415

• NMR resonance assignments of sparsely labeled proteins: amide proton exchange correlations in native and denatured states.

  Journal of the American Chemical Society 20090415

• Chiral induction, memory, and amplification in porphyrin homoaggregates based on electrostatic interactions.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20090414

• Gaussian-mixture umbrella sampling.

  The journal of physical chemistry. B 20090409

• Is there an influence of the surrounding material on the response of the alanine dosimetry system?

  Physics in medicine and biology 20090407

• Comparison of R-metalaxyl and rac-metalaxyl in acute, chronic, and sublethal effect on aquatic organisms: Daphnia magna, Scenedesmus quadricanda, and Danio rerio.

  Environmental toxicology 20090401

• Dimethylamino acid esters as biodegradable and reversible transdermal permeation enhancers: effects of linking chain length, chirality and polyfluorination.

  Pharmaceutical research 20090401

• Changing the recognition site of a conjugative relaxase by rational design.

  Biotechnology journal 20090401

• Effects of oral supplementation with glutamine and alanyl-glutamine on glutamine, glutamate, and glutathione status in trained rats and subjected to long-duration exercise.

  Nutrition (Burbank, Los Angeles County, Calif.) 20090401

• Alanine scanning mutagenesis of the second extracellular loop of type 1 corticotropin-releasing factor receptor revealed residues critical for peptide binding.

  Molecular pharmacology 20090401

• Characterizing pesticide sorption and degradation in macro scale biopurification systems using column displacement experiments.

  Environmental pollution (Barking, Essex : 1987) 20090401

• Ab initio investigation of the hydration of deprotonated amino acids.

  Journal of the American Society for Mass Spectrometry 20090401

• Breast-feeding modifies the association of PPARgamma2 polymorphism Pro12Ala with growth in early life: the Generation R Study.

  Diabetes 20090401

• Metabolic abnormalities in fronto-striatal-thalamic white matter tracts in schizophrenia.

  Schizophrenia research 20090401

• Methyl-detected 'out-and-back' NMR experiments for simultaneous assignments of Alabeta and Ilegamma2 methyl groups in large proteins.

  Journal of biomolecular NMR 20090401

• The Pro12Ala polymorphism of the PPARgamma2 gene is associated with hepatic glucose uptake during hyperinsulinemia in subjects with type 2 diabetes mellitus.

  Metabolism: clinical and experimental 20090401

• A sequence element that tunes Escherichia coli tRNA(Ala)(GGC) to ensure accurate decoding.

  Nature structural & molecular biology 20090401

• Bases in the anticodon loop of tRNA(Ala)(GGC) prevent misreading.

  Nature structural & molecular biology 20090401

• Qualitative analysis of collective mode frequency shifts in L-alanine using terahertz spectroscopy.

  Analytical chemistry 20090401

• Novel type of Streptococcus pneumoniae causing multidrug-resistant acute otitis media in children.

  Emerging infectious diseases 20090401

• [Information needed to specify a protein structure: structure and thermodynamics of a highly simplified bovine pancreatic trypsin inhibitor].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20090401

• Oligomeric amyloid beta-protein as a therapeutic target in Alzheimer's disease: its significance based on its distinct localization and the occurrence of a familial variant form.

  Current Alzheimer research 20090401

• ALT1-encoded alanine aminotransferase plays a central role in the metabolism of alanine in Saccharomyces cerevisiae.

  Canadian journal of microbiology 20090401

• Pure and doped triglycine sulfate crystals: growth and characterization.

  Annals of the New York Academy of Sciences 20090401

• The pH dependence of the allosteric response of human liver pyruvate kinase to fructose-1,6-bisphosphate, ATP, and alanine.

  Archives of biochemistry and biophysics 20090401

• Pseudo-replication of [GADV]-proteins and origin of life.

  International journal of molecular sciences 20090401

• Ala147Thr substitution in translocator protein is associated with adult separation anxiety in patients with depression.

  Psychiatric genetics 20090401

• Inhibition of protein 4.1 R and NuMA interaction by mutagenization of their binding-sites abrogates nuclear localization of 4.1 R.

  Clinical and translational science 20090401

• A thorough study on the use of quantitative 1H NMR in Rioja red wine fermentation processes.

  Journal of agricultural and food chemistry 20090325

• Enantioselectivity of amino acids using chiral sensors based on nanotubes.

  The Journal of chemical physics 20090321

• Reversed-phase high performance liquid chromatographic separation of diastereomers of beta-amino alcohols and microwave assisted synthesis of Marfey's reagent, its chiral variants and diastereomers.

  Journal of chromatography. A 20090320

• Polyol-specific long-chain dehydrogenases/reductases of mannitol metabolism in Aspergillus fumigatus: biochemical characterization and pH studies of mannitol 2-dehydrogenase and mannitol-1-phosphate 5-dehydrogenase.

  Chemico-biological interactions 20090316

• Improved design for high resolution electrospray ionization ion mobility spectrometry.

  Talanta 20090315

• Vibrational analysis of amino acids and short peptides in hydrated media. IV. Amino acids with hydrophobic side chains: L-alanine, L-valine, and L-isoleucine.

  The journal of physical chemistry. B 20090312

• Distribution of conformations sampled by the central amino acid residue in tripeptides inferred from amide I band profiles and NMR scalar coupling constants.

  The journal of physical chemistry. B 20090305

• Soman induces ictogenesis in the amygdala and interictal activity in the hippocampus that are blocked by a GluR5 kainate receptor antagonist in vitro.

  Neuroscience 20090303

• 'Naked-eye' enantioselective chemosensors for N-protected amino acid anions bearing thiourea units.

  Chirality 20090301

• Chromatographic separation of enantiomers of non-protein alpha-amino acids after derivatization with Marfey's reagent and its four variants.

  Amino acids 20090301

• Enantioselective degradation of metalaxyl in anaerobic activated sewage sludge.

  Bulletin of environmental contamination and toxicology 20090301

• A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation.

  Molecular pharmacology 20090301

• Heteronuclear dipolar recoupling in multiple-spin system under fast magic-angle spinning.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20090301

• Protein kinase A regulates production of virulence determinants by the entomopathogenic fungus, Metarhizium anisopliae.

  Fungal genetics and biology : FG & B 20090301

• Metabolic fate of plasma glucose during hyperglycemia in impaired glucose tolerance: evidence for further early defects in the pathogenesis of type 2 diabetes.

  American journal of physiology. Endocrinology and metabolism 20090301

• Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux.

  Journal of neurochemistry 20090301

• Expression of the phosphonoalanine-degradative gene cluster from Variovorax sp. Pal2 is induced by growth on phosphonoalanine and phosphonopyruvate.

  FEMS microbiology letters 20090301

• A single U/C nucleotide substitution changing alanine to valine in the beet necrotic yellow vein virus P25 protein promotes increased virus accumulation in roots of mechanically inoculated, partially resistant sugar beet seedlings.

  The Journal of general virology 20090301

• Contribution of each amino acid residue in polymyxin B(3) to antimicrobial and lipopolysaccharide binding activity.

  Chemical & pharmaceutical bulletin 20090301

• Characterization of endogenous pyridoxal 5'-phosphate-dependent alanine racemase from Bacillus pseudofirmus OF4.

  Journal of bioscience and bioengineering 20090301

• Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein.

  The European journal of neuroscience 20090301

• Excitotoxicity-induced endocytosis confers drug targeting in cerebral ischemia.

  Annals of neurology 20090301

• A potential of mean force estimator based on nonequilibrium work exponential averages.

  Physical chemistry chemical physics : PCCP 20090227

• Intramolecular hydrogen transfer in the ionization process of alpha-alanine.

  Physical chemistry chemical physics : PCCP 20090227

• Resampling improves the efficiency of a 'fast-switch' equilibrium sampling protocol.

  The Journal of chemical physics 20090227

• Noncooperative Formation of the off-pathway molten globule during folding of the alpha-beta parallel protein apoflavodoxin.

  Journal of the American Chemical Society 20090225

• Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe.

  Journal of the American Chemical Society 20090225

• D-serine induces lipid and protein oxidative damage and decreases glutathione levels in brain cortex of rats.

  Brain research 20090223

• Structurally sensitive anharmonic Calpha-D stretch vibration in deuterated peptides.

  The journal of physical chemistry. B 20090219

• Vancomycin resistance: modeling backbone variants with D-Ala-D-Ala and D-Ala-D-Lac peptides.

  Bioorganic & medicinal chemistry letters 20090215

• Design, synthesis, and evaluation of potent, nonpeptidic mimetics of second mitochondria-derived activator of caspases.

  Journal of medicinal chemistry 20090212

• Novel oral absorption system containing polyamines and bile salts enhances drug transport via both transcellular and paracellular pathways across Caco-2 cell monolayers.

  International journal of pharmaceutics 20090209

• Kinetic and thermodynamic control in the stereoselective formation of trans- and cis-2-ferrocenyl-3-pivaloyl-4-alkyl-1,3-oxazolidin-5-ones.

  Organic & biomolecular chemistry 20090207

• Sequence specificity of the PHSRN peptide from fibronectin on corneal epithelial migration.

  Biochemical and biophysical research communications 20090206

• Mutation of critical serine residues in HIV-1 matrix result in an envelope incorporation defect which can be rescued by truncation of the gp41 cytoplasmic tail.

  Virology 20090205

• Imidazolium-functionalized BINOL as a multifunctional receptor for chromogenic and chiral anion recognition.

  Organic letters 20090205

• 4D 1H-13C NMR spectroscopy for assignments of alanine methyls in large and complex protein structures.

  Journal of the American Chemical Society 20090204

• A germline mutation (A339V) in thyroid transcription factor-1 (TITF-1/NKX2.1) in patients with multinodular goiter and papillary thyroid carcinoma.

  Journal of the National Cancer Institute 20090204

• Tensile mechanics of alanine-based helical polypeptide: force spectroscopy versus computer simulations.

  Biophysical journal 20090204

• Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growth.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090204

• ATP competitive inhibitors of D-alanine-D-alanine ligase based on protein kinase inhibitor scaffolds.

  Bioorganic & medicinal chemistry 20090201

• Solid phase synthesis of peptides containing novel amino acids, substituted 3-benzimidazolealanines.

  Amino acids 20090201

• A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer.

  Investigational new drugs 20090201

• Prolonged L-alanine exposure induces changes in metabolism, Ca(2+) handling and desensitization of insulin secretion in clonal pancreatic beta-cells.

  Clinical science (London, England : 1979) 20090201

• Responses to acute and chronic desiccation stress in Enchytraeus (Oligochaeta: Enchytraeidae).

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20090201

• A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP.

  American journal of physiology. Cell physiology 20090201

• Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.

  Neuropharmacology 20090201

• Engineering of the alpha-amylase from Geobacillus stearothermophilus US100 for detergent incorporation.

  Biotechnology and bioengineering 20090201

• Characterizing pesticide sorption and degradation in microscale biopurification systems using column displacement experiments.

  Environmental pollution (Barking, Essex : 1987) 20090201

• The manganese superoxide dismutase Val16Ala polymorphism is associated with decreased risk of diabetic nephropathy in Chinese patients with type 2 diabetes.

  Molecular and cellular biochemistry 20090201

• Functional evaluation of serine 252 of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase.

  Biochimie 20090201

• A disulfide linked model of the complement protein C8gamma complexed with C8alpha indel peptide.

  Journal of molecular modeling 20090201

• Pyridylalanine-containing hydroxamic acids as selective HDAC6 inhibitors.

  ChemMedChem 20090201

• An efficient protocol for the complete incorporation of methyl-protonated alanine in perdeuterated protein.

  Journal of biomolecular NMR 20090201

• Ribosome hijacking: a role for small protein B during trans-translation.

  EMBO reports 20090201

• An approach to characterizing single-subunit mutations in multimeric prepores and pores of anthrax protective antigen.

  Protein science : a publication of the Protein Society 20090201

• Selection and structural analysis of de novo proteins from an alpha3beta3 genetic library.

  Protein science : a publication of the Protein Society 20090201

• A long, naturally presented immunodominant epitope from NY-ESO-1 tumor antigen: implications for cancer vaccine design.

  Cancer research 20090201

• Both sides now: multiple interactions of ATP with pannexin-1 hemichannels. Focus on 'A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP'.

  American journal of physiology. Cell physiology 20090201

• Oral glutamine dipeptide prevents against prolonged hypoglycemia induced by Detemir insulin in rats.

  Biological & pharmaceutical bulletin 20090201

• Chronic ethanol and withdrawal effects on kainate receptor-mediated excitatory neurotransmission in the rat basolateral amygdala.

  Alcohol (Fayetteville, N.Y.) 20090201

• Helix 3 is necessary and sufficient for prion protein's anti-Bax function.

  Journal of neurochemistry 20090201

• Two novel bovine somatotropin species generated from a common dehydroalanine intermediate.

  The protein journal 20090201

• Committed neuronal precursors confer astrocytic potential on residual neural precursor cells.

  Developmental cell 20090201

• Fate and distribution of pyrimethanil, metalaxyl, dichlofluanid and penconazol fungicides from treated grapes intended for winemaking.

  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090201

• Effects of amino acids on microcystin production of the Microcystis aeruginosa.

  Journal of hazardous materials 20090130

• New urea-based surfactants derived from alpha,omega-amino acids.

  The journal of physical chemistry. B 20090129

• Phosphorylation of DeltaFosB mediates its stability in vivo.

  Neuroscience 20090123

• The C-terminal of CysM from Mycobacterium tuberculosis protects the aminoacrylate intermediate and is involved in sulfur donor selectivity.

  FEBS letters 20090122

• Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090121

• Multidimensional Langevin modeling of biomolecular dynamics.

  The Journal of chemical physics 20090121

• The partially folded homodimeric intermediate of Escherichia coli aspartate aminotransferase contains a 'molten interface' structure.

  Biochemistry 20090120

• Competition between reversible aggregation and loop formation in denatured iso-1-cytochrome c.

  Biochemistry 20090120

• Concise preparation of tetra-orthogonally protected (2S,6R)-lanthionines.

  The Journal of organic chemistry 20090116

• Subunit-dependent postsynaptic expression of kainate receptors on hippocampal interneurons in area CA1.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090114

• Structure-function analysis of RAMP1 by alanine mutagenesis.

  Biochemistry 20090113

• Polo-like kinase 1 phosphorylates and regulates Bcl-x(L) during pironetin-induced apoptosis.

  Oncogene 20090108

• Ramachandran revisited. DFT energy surfaces of diastereomeric trialanine peptides in the gas phase and aqueous solution.

  The journal of physical chemistry. B 20090108

• The site for the allosteric activator GTP of Escherichia coli UMP kinase.

  FEBS letters 20090105

• Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of multiple sclerosis.

  Neuroscience letters 20090102

• Characterization of a histidine- and alanine-rich protein showing interaction with calreticulin in rice.

  Amino acids 20090101

• Central L-alanine reduces energy expenditure with a hypnotic effect under an acute stressful condition in neonatal chicks.

  Amino acids 20090101

• Determination of the efficacy of terbinafine hydrochloride nail solution in the topical treatment of dermatophytosis in a guinea pig model.

  Mycoses 20090101

• Radical scavengers for elderly patients with age-related hearing loss.

  Acta oto-laryngologica 20090101

• Subtype selective kainic acid receptor agonists: discovery and approaches to rational design.

  Medicinal research reviews 20090101

• Interaction between PPARG Pro12Ala and ADIPOQ G276T concerning cholesterol levels in childhood obesity.

  International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity 20090101

• Medical reference dosimetry using EPR measurements of alanine: development of an improved method for clinical dose levels.

  Acta oncologica (Stockholm, Sweden) 20090101

• Antagonism of recombinant and native GluK3-containing kainate receptors.

  Neuropharmacology 20090101

• A conserved mechanism for nitrile metabolism in bacteria and plants.

  The Plant journal : for cell and molecular biology 20090101

• ACET is a highly potent and specific kainate receptor antagonist: characterisation and effects on hippocampal mossy fibre function.

  Neuropharmacology 20090101

• Transepithelial transport of the group II metabotropic glutamate 2/3 receptor agonist (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate (LY354740) and its prodrug (1S,2S,5R,6S)-2-[(2'S)-(2'-amino)propionyl]aminobicyclo[3.1.0]hexane-2,6-dicarboxylate (LY544344).

  Drug metabolism and disposition: the biological fate of chemicals 20090101

• Enantioselective visualization of D-alanine in rat anterior pituitary gland: localization to ACTH-secreting cells.

  Analytical and bioanalytical chemistry 20090101

• Sjogren's syndrome: promising, new treatment options besides nizatidine.

  Modern rheumatology 20090101

• Structural basis of NR2B-selective antagonist recognition by N-methyl-D-aspartate receptors.

  Molecular pharmacology 20090101

• A preliminary report on the effect of dimeric rhGDF-5 and its monomeric form rhGDF-5C465A on bone healing of rat cranial defects.

  Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 20090101

• Mutation of H63 and its catalytic affect on the methionine aminopeptidase from Escherichia coli.

  Biochimica et biophysica acta 20090101

• Aging and alpha-synuclein affect synaptic plasticity in the dentate gyrus.

  Journal of neural transmission (Vienna, Austria : 1996) 20090101

• Epidermodysplasia verruciformis in a HIV-positive patient homozygous for the c917A-->T polymorphism in the TMC8/EVER2 gene.

  Dermatology (Basel, Switzerland) 20090101

• Muscarinic receptor regulation of osmosensitive taurine transport in human SH-SY5Y neuroblastoma cells.

  Journal of neurochemistry 20090101

• Requirement of Notch activation during regeneration of the intestinal epithelia.

  American journal of physiology. Gastrointestinal and liver physiology 20090101

• Mutation in a D-alanine-D-alanine ligase of Azospirillum brasilense Cd results in an overproduction of exopolysaccharides and a decreased tolerance to saline stress.

  FEMS microbiology letters 20090101

• Design, synthesis and biological evaluation of novel bicyclo[1.1.1]pentane-based omega-acidic amino acids as glutamate receptors ligands.

  Bioorganic & medicinal chemistry 20090101

• Compound-specific nitrogen isotope analysis of D-alanine, L-alanine, and valine: application of diastereomer separation to delta15N and microbial peptidoglycan studies.

  Analytical chemistry 20090101

• Mitochondrial tRNALeu/Lys and ATPase 6/8 gene variations in spinocerebellar ataxias.

  Neuro-degenerative diseases 20090101

• Efficacy and safety of rebamipide for the treatment of dry mouth symptoms in patients with Sjögren's syndrome: a double-blind placebo-controlled multicenter trial.

  Modern rheumatology 20090101

• Simultaneous detection of mitochondrial DNA depletion and single-exon deletion in the deoxyguanosine gene using array-based comparative genomic hybridisation.

  Archives of disease in childhood 20090101

• Evidence that L-glutamine is better than L-alanine as gluconeogenic substrate in perfused liver of weaned fasted rats submitted to short-term insulin-induced hypoglycaemia.

  Cell biochemistry and function 20090101

• Structure-function relationships of the non-lanthionine-containing peptide (class II) bacteriocins produced by gram-positive bacteria.

  Current pharmaceutical biotechnology 20090101

• The oligomerization of OxyR in Escherichia coli.

  Protein science : a publication of the Protein Society 20090101

• Enterococcal surface protein Esp is not essential for cell adhesion and intestinal colonization of Enterococcus faecium in mice.

  BMC microbiology 20090101

• Ligands for ionotropic glutamate receptors.

  Progress in molecular and subcellular biology 20090101

• Comparative genomic analyses of nickel, cobalt and vitamin B12 utilization.

  BMC genomics 20090101

• Effect of a dominant-negative form of ADAM10 in a mouse model of Alzheimer's disease.

  Journal of Alzheimer's disease : JAD 20090101

• The terahertz dance of water with the proteins: the effect of protein flexibility on the dynamical hydration shell of ubiquitin.

  Faraday discussions 20090101

• Taurine depletion by beta-alanine inhibits induction of hepatotoxicity in mice treated acutely with carbon tetrachloride.

  Advances in experimental medicine and biology 20090101

• Physicochemical study of the sorption of pesticides by wood components.

  Journal of environmental quality 20090101

• Atomic force microscopy study of germination and killing of Bacillus atrophaeus spores.

  Journal of molecular recognition : JMR 20090101

• Glycerol: an unexpected major metabolite of energy metabolism by the human malaria parasite.

  Malaria journal 20090101

• A small molecule inhibitor of signal peptide peptidase inhibits Plasmodium development in the liver and decreases malaria severity.

  PloS one 20090101

• Chapter 21. In vitro studies of lantibiotic biosynthesis.

  Methods in enzymology 20090101

• Synthesis and peptide coupling of protected pyrrolylalanine.

  Advances in experimental medicine and biology 20090101

• Synthesis & biological evaluation of PYY(3-36) analogs substituted with alanine.

  Advances in experimental medicine and biology 20090101

• Rebamipide-promoted restoration of gastric mucosal sonic hedgehog expression after early Helicobacter pylori eradication.

  Digestion 20090101

• Cu(II)-catalyzed reactions in ternary [Cu(AA)(AA - H)]+ complexes (AA = Gly, Ala, Val, Leu, Ile, t-Leu, Phe).

  European journal of mass spectrometry (Chichester, England) 20090101

• Study of pyruvate kinase activity in human astrocytomas - alanine-inhibition test revisted.

  Neurology India 20090101

• Conserved threonine residues within the A-loop of the receptor NIK differentially regulate the kinase function required for antiviral signaling.

  PloS one 20090101

• PPARgamma Pro12Ala polymorphism and risk of acute coronary syndrome in a prospective study of Danes.

  BMC medical genetics 20090101

• [Autoimmune response in HIV-infected patients is directed against CD4 domain 4].

  Voprosy virusologii 20090101

• The GxxxG motif in the transmembrane domain of AbetaPP plays an essential role in the interaction of CTF beta with the gamma-secretase complex and the formation of amyloid-beta.

  Journal of Alzheimer's disease : JAD 20090101

• Neurochemical changes after acute binge toluene inhalation in adolescent and adult rats: a high-resolution magnetic resonance spectroscopy study.

  Neurotoxicology and teratology 20090101

• Protein phosphorylation by semisynthesis: from paper to practice.

  Methods in enzymology 20090101

• Bacillus cereus spores release alanine that synergizes with inosine to promote germination.

  PloS one 20090101

• A second case of Hb Fontainebleau [alpha21(B2)Ala-->Pro] in an individual with microcytosis.

  Hemoglobin 20090101

• Mutagenesis of the fusion peptide-like domain of hepatitis C virus E1 glycoprotein: involvement in cell fusion and virus entry.

  Journal of biomedical science 20090101

• Reactions of Cre with methylphosphonate DNA: similarities and contrasts with Flp and vaccinia topoisomerase.

  PloS one 20090101

• L-Alanine augments rhizobacteria-induced systemic resistance in cucumber.

  Folia microbiologica 20090101

• Prediction of hot spot residues at protein-protein interfaces by combining machine learning and energy-based methods.

  BMC bioinformatics 20090101

• Development of freeze-dried biosynthetic Factor VIII: I. A case study in the optimization of formulation.

  Pharmaceutical development and technology 20090101

• Stringency of the 2-His-1-Asp active-site motif in prolyl 4-hydroxylase.

  PloS one 20090101

• Deprotonation of the Asp1-Ala2 peptide bond induces modification of the dynamic copper(II) environment in the amyloid-beta peptide near physiological pH.

  Angewandte Chemie (International ed. in English) 20090101

• BMAA neurotoxicity in Drosophila.

  Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20090101

• [Dissolution enthalpies of DL-alpha-alanine and dipeptides of aliphatic series in aqueous solutions of KCl].

  Biofizika 20090101

• Genome subtraction for novel target definition in Salmonella typhi.

  Bioinformation 20090101

• Development and use of the incremental twitch subtraction MUNE method in mice.

  Supplements to Clinical neurophysiology 20090101

• The natriuretic peptide neurohormonal system modulation by vasopeptidase inhibitors--the novel therapeutical approach of hypertension treatment.

  Folia medica Cracoviensia 20090101

• Terahertz spectra and normal mode analysis of the crystalline VA class dipeptide nanotubes.

  Journal of the American Chemical Society 20081231

• Sequence-specific unusual (1-->2)-type helical turns in alpha/beta-hybrid peptides.

  Journal of the American Chemical Society 20081231

• The effect of rod domain A148V mutation of neurofilament light chain on filament formation.

  BMB reports 20081231

• CS-917, a fructose 1,6-bisphosphatase inhibitor, improves postprandial hyperglycemia after meal loading in non-obese type 2 diabetic Goto-Kakizaki rats.

  European journal of pharmacology 20081228

• The CP2 domain of leucyl-tRNA synthetase is crucial for amino acid activation and post-transfer editing.

  The Journal of biological chemistry 20081226

• DNA repair and free radicals, new insights into the mechanism of spore photoproduct lyase revealed by single amino acid substitution.

  The Journal of biological chemistry 20081226

• The MurC ligase essential for peptidoglycan biosynthesis is regulated by the serine/threonine protein kinase PknA in Corynebacterium glutamicum.

  The Journal of biological chemistry 20081226

• Alanine polypeptide structural fingerprints at room temperature: what can be gained from non-harmonic Car-Parrinello molecular dynamics simulations.

  The journal of physical chemistry. A 20081225

• An investigation of protonation sites and conformations of protonated amino acids by IRMPD spectroscopy.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20081222

• Intrinsic volumetric properties of trialanine isomers in aqueous solution.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20081222

• Identification and characterization of a novel fibril forming peptide in fungal starch binding domain.

  Biochemical and biophysical research communications 20081219

• Phosphorylation of CAP-G is required for its chromosomal DNA localization during mitosis.

  Biochemical and biophysical research communications 20081219

• Significance of the long-chain organic cation structure in the sorption of the penconazole and metalaxyl fungicides by organo clays.

  Journal of hazardous materials 20081215

• Synthesis of a novel fluorescent probe and investigation on its interaction with nucleic acid and analytical application.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081215

• Spectral characterization, cyclic voltammetry, morphology, biological activities and DNA cleaving studies of amino acid Schiff base metal(II) complexes.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081215

• Loop B is a major structural component of the 5-HT3 receptor.

  Biophysical journal 20081215

• Regulated movement of CD4 in and out of the immunological synapse.

  Journal of immunology (Baltimore, Md. : 1950) 20081215

• A novel synthetic approach to C-glycosyl-D- and L-alanines.

  Molecules (Basel, Switzerland) 20081215

• Manganese superoxide dismutase gene Ala-9Val polymorphism might be related to the severity of abnormal involuntary movements in Korean schizophrenic patients.

  Progress in neuro-psychopharmacology & biological psychiatry 20081212

• Unchanged beta-adrenergic stimulation of cardiac L-type calcium channels in Ca v 1.2 phosphorylation site S1928A mutant mice.

  The Journal of biological chemistry 20081212

• Kinetic characterization of lipid II-Ala:alanyl-tRNA ligase (MurN) from Streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates.

  The Journal of biological chemistry 20081212

• Constitutive activity of JNK2 alpha2 is dependent on a unique mechanism of MAPK activation.

  The Journal of biological chemistry 20081212

• Role of intermonomer ionic bridges in the stabilization of the actin filament.

  The Journal of biological chemistry 20081212

• A novel protein domain induces high affinity selenocysteine insertion sequence binding and elongation factor recruitment.

  The Journal of biological chemistry 20081212

• Discovery of new inhibitors of D-alanine:D-alanine ligase by structure-based virtual screening.

  Journal of medicinal chemistry 20081211

• Tyr-51 is the proton donor-acceptor for NAD(H)-dependent interconversion of xylose and xylitol by Candida tenuis xylose reductase (AKR2B5).

  FEBS letters 20081210

• Early interrogation and recognition of DNA sequence by indirect readout.

  Structure (London, England : 1993) 20081210

• Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops.

  Structure (London, England : 1993) 20081210

• Selenocysteine positional variants reveal contributions to copper binding from cysteine residues in domains 2 and 3 of human copper chaperone for superoxide dismutase.

  Biochemistry 20081209

• Novel toxic shock syndrome toxin-1 amino acids required for biological activity.

  Biochemistry 20081209

• Hyperstable miniproteins: additive effects of D- and L-Ala mutations.

  Organic & biomolecular chemistry 20081207

• Enzymes containing porous polymersomes as nano reaction vessels for cascade reactions.

  Organic & biomolecular chemistry 20081207

• On the pH regulation of plant aquaporins.

  The Journal of biological chemistry 20081205

• Identifying key components of the PrPC-PrPSc replicative interface.

  The Journal of biological chemistry 20081205

• An Arf1 GTPase mutant with different responses to GEF inhibitors.

  Biochemical and biophysical research communications 20081205

• Dual assay for MCLV3 activity reveals structure-activity relationship of CLE peptides.

  Biochemical and biophysical research communications 20081205

• High-affinity insulin binding: insulin interacts with two receptor ligand binding sites.

  Biochemistry 20081202

• The Pro12Ala polymorphism of the PPAR-gamma2 gene affects associations of fish intake and marine n-3 fatty acids with glucose metabolism.

  European journal of clinical nutrition 20081201

• The catalytic effect of L- and D-histidine on alanine and lysine peptide formation.

  Journal of inorganic biochemistry 20081201

• The orphan transporter Rxt1/NTT4 (SLC6A17) functions as a synaptic vesicle amino acid transporter selective for proline, glycine, leucine, and alanine.

  Molecular pharmacology 20081201

• Dehydroalanine analog of glutathione: an electrophilic busulfan metabolite that binds to human glutathione S-transferase A1-1.

  The Journal of pharmacology and experimental therapeutics 20081201

• Alanine-dependent reactions of 5'-deoxypyridoxal in water.

  Bioorganic chemistry 20081201

• Effect of endothelium-specific insulin resistance on endothelial function in vivo.

  Diabetes 20081201

• Purinergic activation of anion conductance and osmolyte efflux in cultured rat hippocampal neurons.

  American journal of physiology. Cell physiology 20081201

• Toxicity of chiral pesticide Rac-metalaxyl and R-metalaxyl to Daphnia magna.

  Bulletin of environmental contamination and toxicology 20081201

• Studies of peptide a- and b-type fragment ions using stable isotope labeling and integrated ion mobility/tandem mass spectrometry.

  Journal of the American Society for Mass Spectrometry 20081201

• Can alpha- and beta-alanine containing peptides be distinguished based on the CID spectra of their protonated ions?

  Journal of the American Society for Mass Spectrometry 20081201

• Analyzing the catalytic role of Asp97 in the methionine aminopeptidase from Escherichia coli.

  The FEBS journal 20081201

• Expression, crystallization and preliminary X-ray crystallographic analysis of Xoo0352, D-alanine-D-alanine ligase A, from Xanthomonas oryzae pv. oryzae.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20081201

• Target sequence polymorphism of human manganese superoxide dismutase gene and its association with cancer risk: a review.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20081201

• Detection of a novel silent deletion, a missense mutation and a nonsense mutation in TCOF1.

  Pediatrics international : official journal of the Japan Pediatric Society 20081201

• Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (PPARgamma) gene in inflammatory bowel disease.

  Journal of gastrointestinal and liver diseases : JGLD 20081201

• Identification and determination of the intra- and extracellular aminopeptidase activity by synthetic L-Ala-, L-Tyr-, and L-Phe-beta-napthylamide.

  Die Pharmazie 20081201

• Reversible intramolecular hydrogen transfer between cysteine thiyl radicals and glycine and alanine in model peptides: absolute rate constants derived from pulse radiolysis and laser flash photolysis.

  The journal of physical chemistry. B 20081127

• Crystal structure of Tk-subtilisin folded without propeptide: requirement of propeptide for acceleration of folding.

  FEBS letters 20081126

• Neutralizing activity of antibodies to the V3 loop region of HIV-1 gp120 relative to their epitope fine specificity.

  Virology 20081125

• Asymmetry in the lipid affinity of bihelical amphipathic peptides. A structural determinant for the specificity of ABCA1-dependent cholesterol efflux by peptides.

  The Journal of biological chemistry 20081121

• Role of the HIV gp120 conserved domain 1 in processing and viral entry.

  The Journal of biological chemistry 20081121

• [2,3]-Sigmatropic rearrangements of 3-sulfinyl dihydropyrans: application to the syntheses of the cores of ent-dysiherbaine and deoxymalayamicin A.

  The Journal of organic chemistry 20081121

• Quantifying the fraction of glycine and alanine in beta-sheet and helical conformations in spider dragline silk using solid-state NMR.

  Chemical communications (Cambridge, England) 20081121

• Rebamipide affects the efficiency of colchicine for the herpes simplex virus-induced inflammation in a Behcet's disease mouse model.

  European journal of pharmacology 20081119

• Novel ATP13A2 variant associated with Parkinson disease in Taiwan and Singapore.

  Neurology 20081118

• A comparative study on the growth and characterization of nonlinear optical amino acid crystals: L-alanine (LA) and L-alanine alaninium nitrate (LAAN).

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081115

• Synthesis and structural study of cyclic 5-aminovaleric acid-linked beta-Ala-beta-Ala dipeptides.

  Bioorganic & medicinal chemistry letters 20081115

• Synthesis of beta-hydroxy-alpha-amino acids with a reengineered alanine racemase.

  Bioorganic & medicinal chemistry letters 20081115

• A promiscuous aminoacyl-tRNA synthetase that incorporates cysteine, methionine, and alanine homologs into proteins.

  Bioorganic & medicinal chemistry letters 20081115

• Synaptotagmin C2B domain regulates Ca2+-triggered fusion in vitro: critical residues revealed by scanning alanine mutagenesis.

  The Journal of biological chemistry 20081114

• De novo design of a bolaamphiphilic peptide with only natural amino acids.

  Macromolecular bioscience 20081110

• Effects of monocrotaline on energy metabolism in the rat liver.

  Toxicology letters 20081110

• Oxidative stress induces gastric epithelial permeability through claudin-3.

  Biochemical and biophysical research communications 20081107

• Structure of N,N'-bis(amino acids) in the solid state and in solution. A 13C and 15N CPMAS NMR study.

  The Journal of organic chemistry 20081107

• Azido-derivatized compounds as IR probes of local electrostatic environment: Theoretical studies.

  The Journal of chemical physics 20081107

• Oligo(p-phenylenevinylene)-peptide conjugates: synthesis and self-assembly in solution and at the solid-liquid interface.

  Journal of the American Chemical Society 20081105

• Crystal structure and enantiomer selection by D-alanyl carrier protein ligase DltA from Bacillus cereus.

  Biochemistry 20081104

• Anti-inflammatory effects of rebamipide according to Helicobacter pylori status in patients with chronic erosive gastritis: a randomized sucralfate-controlled multicenter trial in China-STARS study.

  Digestive diseases and sciences 20081101

• Circadian changes of D-alanine and related compounds in rats and the effect of restricted feeding on their amounts.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081101

• An open-labeled study of rebamipide treatment in chronic gastritis patients with dyspeptic symptoms refractory to proton pump inhibitors.

  Digestive diseases and sciences 20081101

• The varitint-waddler mouse phenotypes and the TRPML3 ion channel mutation: cause and consequence.

  Pflugers Archiv : European journal of physiology 20081101

• Introduction into Ca(v)2.1 of the homologous mutation of Ca(v)1.2 causing the Timothy syndrome questions the role of V421 in the phenotypic definition of P-type Ca(2+) channel.

  Pflugers Archiv : European journal of physiology 20081101

• The herbicide flamprop-M-methyl has a new antimicrotubule mechanism of action.

  Pest management science 20081101

• Site directed mutagenesis studies of FAD-dependent glucose dehydrogenase catalytic subunit of Burkholderia cepacia.

  Biotechnology letters 20081101

• Continuous metadynamics in essential coordinates as a tool for free energy modelling of conformational changes.

  Journal of molecular modeling 20081101

• Fragmentation of intra-peptide and inter-peptide disulfide bonds of proteolytic peptides by nanoESI collision-induced dissociation.

  Analytical and bioanalytical chemistry 20081101

• Functionally important residues of the Tet repressor inducing peptide TIP determined by a complete mutational analysis.

  Gene 20081101

• Dynamics of Abeta turnover and deposition in different beta-amyloid precursor protein transgenic mouse models following gamma-secretase inhibition.

  The Journal of pharmacology and experimental therapeutics 20081101

• Structural analysis of the adenovirus type 2 E3/19K protein using mutagenesis and a panel of conformation-sensitive monoclonal antibodies.

  Molecular immunology 20081101

• The manganese superoxide dismutase Ala16Val dimorphism modulates iron accumulation in human hepatoma cells.

  Free radical biology & medicine 20081101

• D-Alanine:D-alanine ligase as a new target for the flavonoids quercetin and apigenin.

  International journal of antimicrobial agents 20081101

• Significance of ERK nitration in portal hypertensive gastropathy and its therapeutic implications.

  American journal of physiology. Gastrointestinal and liver physiology 20081101

• Investigation of substrate binding and product stereochemistry issues in two linoleate 9-lipoxygenases.

  Lipids 20081101

• Mutational analysis of vaccinia virus mRNA cap (guanine-N7) methyltransferase reveals essential contributions of the N-terminal peptide that closes over the active site.

  RNA (New York, N.Y.) 20081101

• Direct and indirect separations of five isomers of Brivanib Alaninate using chiral high-performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081101

• An unlikely silk: the composite material of green lacewing cocoons.

  Biomacromolecules 20081101

• Crucial role of aspartic acid at position 265 in the CH2 domain for murine IgG2a and IgG2b Fc-associated effector functions.

  Journal of immunology (Baltimore, Md. : 1950) 20081101

• Novel 95G>A (R32K) somatic mosaic connexin 32 mutation.

  Muscle & nerve 20081101

• In vitro susceptibility of Pythium insidiosum and a Lagenidium sp to itraconazole, posaconazole, voriconazole, terbinafine, caspofungin, and mefenoxam.

  American journal of veterinary research 20081101

• Simultaneous LIF and retro-reflected beam interference detection for CE.

  Electrophoresis 20081101

• Disordering of the [NbOF5]2- complex anions in bis(glycinium) pentafluoridooxidoniobate(V) and bis(beta-alaninium) pentafluoridooxidoniobate(V) dihydrate.

  Acta crystallographica. Section C, Crystal structure communications 20081101

• Calculating free-energy profiles in biomolecular systems from fast nonequilibrium processes.

  Physical review. E, Statistical, nonlinear, and soft matter physics 20081101

• Natural homolog of tRNA synthetase editing domain rescues conditional lethality caused by mistranslation.

  The Journal of biological chemistry 20081031

• Gly-Ala repeats induce position- and substrate-specific regulation of 26 S proteasome-dependent partial processing.

  The Journal of biological chemistry 20081031

• Effect of Hfq on RprA-rpoS mRNA pairing: Hfq-RNA binding and the influence of the 5' rpoS mRNA leader region.

  Biochemistry 20081028

• Preserving the Boltzmann ensemble in replica-exchange molecular dynamics.

  The Journal of chemical physics 20081028

• Insights into the catalytic mechanism of tyrosine phenol-lyase from X-ray structures of quinonoid intermediates.

  The Journal of biological chemistry 20081024

• Charged amino acid residues 997-1000 of human apolipoprotein B100 are critical for the initiation of lipoprotein assembly and the formation of a stable lipidated primordial particle in McA-RH7777 cells.

  The Journal of biological chemistry 20081024

• NaV1.7 gain-of-function mutations as a continuum: A1632E displays physiological changes associated with erythromelalgia and paroxysmal extreme pain disorder mutations and produces symptoms of both disorders.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20081022

• Lysine and arginine residues do not increase the helicity of alanine-rich peptide helices.

  Chemical communications (Cambridge, England) 20081021

• Domain mapping of the polycystin-2 C-terminal tail using de novo molecular modeling and biophysical analysis.

  The Journal of biological chemistry 20081017

• Phosphorylation of MyoGEF on Thr-574 by Plk1 promotes MyoGEF localization to the central spindle.

  The Journal of biological chemistry 20081017

• Vibrational spectra of alpha-amino acids in the zwitterionic state in aqueous solution and the solid state: DFT calculations and the influence of hydrogen bonding.

  The journal of physical chemistry. A 20081016

• Suppression of autophagy enhances the cytotoxicity of the DNA-damaging aromatic amine p-anilinoaniline.

  Toxicology and applied pharmacology 20081015

• The role of a conserved histidine residue in a pyruvate-specific Class II aldolase.

  FEBS letters 20081015

• Misacylation of pyrrolysine tRNA in vitro and in vivo.

  FEBS letters 20081015

• Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.

  Cancer research 20081015

• Simulated digestion and antioxidant activity of red wine fractions separated by high speed countercurrent chromatography.

  Journal of agricultural and food chemistry 20081008

• Mechanism of partial agonism at the GluR2 AMPA receptor: Measurements of lobe orientation in solution.

  Biochemistry 20081007

• Computing conformational free energy by deactivated morphing.

  The Journal of chemical physics 20081007

• Pex10p functions as an E3 ligase for the Ubc4p-dependent ubiquitination of Pex5p.

  Biochemical and biophysical research communications 20081003

• Luminescence resonance energy transfer investigation of conformational changes in the ligand binding domain of a kainate receptor.

  The Journal of biological chemistry 20081003

• Diversity of spore germination in response to inosine and L-alanine and its interaction with NaCl and pH in the Bacillus cereus group.

  Journal of applied microbiology 20081001

• N-chloroamino acids cause oxidative protein modifications in the erythrocyte membrane.

  Mechanisms of ageing and development 20081001

• Functional role of arginine 375 in transmembrane helix 6 of multidrug resistance protein 4 (MRP4/ABCC4).

  Molecular pharmacology 20081001

• Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist.

  Molecular pharmacology 20081001

• Muscle-specific IRS-1 Ser->Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle.

  Diabetes 20081001

• Dopamine transporter endocytic determinants: carboxy terminal residues critical for basal and PKC-stimulated internalization.

  Molecular and cellular neurosciences 20081001

• Structural determination of large molecules through the reassembly of optimized fragments.

  Journal of molecular graphics & modelling 20081001

• Electrospray ionization-ion trap mass spectrometry study of PQAAPro and PQProAA mimetic derivatives of the antimalarial primaquine.

  Journal of the American Society for Mass Spectrometry 20081001

• Mutations to the kainate receptor subunit GluR6 binding pocket that selectively affect domoate binding.

  Molecular pharmacology 20081001

• Impact of Tyr to Ala mutations on alpha-synuclein fibrillation and structural properties.

  Biochimica et biophysica acta 20081001

• Control of acute, chronic, and constitutive hyperammonemia by wild-type and genetically engineered Lactobacillus plantarum in rodents.

  Hepatology (Baltimore, Md.) 20081001

• Glutamine supplementation increases Th1-cytokine responses in murine intestinal intraepithelial lymphocytes.

  Cytokine 20081001

• Spectroscopic labeling of A, S/T in the 1H-15N HSQC spectrum of uniformly (15N-13C) labeled proteins.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20081001

• Anomalous J-modulation effects on amino acids in clinical 3T MR spectroscopy.

  AJNR. American journal of neuroradiology 20081001

• FMRFamide neuropeptides and acetylcholine synergistically inhibit egg-laying by C. elegans.

  Nature neuroscience 20081001

• Novel mutations in the IRF6 gene in Brazilian families with Van der Woude syndrome.

  International journal of molecular medicine 20081001

• Brivanib alaninate, a dual inhibitor of vascular endothelial growth factor receptor and fibroblast growth factor receptor tyrosine kinases, induces growth inhibition in mouse models of human hepatocellular carcinoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20081001

• Glucose kinetics during fasting in young children with severe and non-severe malaria in Suriname.

  The American journal of tropical medicine and hygiene 20081001

• Partial multicanonical algorithm for molecular dynamics and Monte Carlo simulations.

  The Journal of chemical physics 20080928

• Analysis of Saccharomyces cerevisiae histone H3 mutants reveals the role of the alphaN helix in nucleosome function.

  Biochemical and biophysical research communications 20080926

• Temperature and pressure dependence of alanine dipeptide studied by multibaric-multithermal molecular dynamics simulations.

  The journal of physical chemistry. B 20080925

• Comparison of 'Polarization inversion with spin exchange at magic angle' and 'geometric analysis of labeled alanines' methods for transmembrane helix alignment.

  Journal of the American Chemical Society 20080924

• Reconstructing atomistic detail for coarse-grained models with resolution exchange.

  The Journal of chemical physics 20080921

• The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cullin5 ubiquitin ligase.

  Journal of molecular biology 20080912

• Interaction studies and alanine scanning analysis of a semi-synthetic split intein reveal thiazoline ring formation from an intermediate of the protein splicing reaction.

  The Journal of biological chemistry 20080912

• The infrared spectrum of solid L-alanine: influence of pH-induced structural changes.

  The journal of physical chemistry. A 20080911

• Use of multidimensional fluorescence resonance energy transfer to establish the orientation of cholecystokinin docked at the type A cholecystokinin receptor.

  Biochemistry 20080909

• Alanine is the main second amino acid in vertebrate proteins and its coding entails increased use of the rare codon GCG.

  Biochemical and biophysical research communications 20080905

• Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1.

  FEBS letters 20080903

• Dispensable residues in the active site of the cytochrome c biogenesis protein CcmH.

  FEBS letters 20080903

• Investigation of the mechanisms of tissue factor-mediated evasion of tumour cells from cellular cytotoxicity.

  Cancer immunology, immunotherapy : CII 20080901

• Enzymatic characterization and crystal structure analysis of the D-alanine-D-alanine ligase from Helicobacter pylori.

  Proteins 20080901

• Lack of association between uncoupling protein-2 Ala55Val polymorphism and incident diabetes in the atherosclerosis risk in communities study.

  Acta diabetologica 20080901

• Aging-resistant organophosphate bioscavenger based on polyethylene glycol-conjugated F338A human acetylcholinesterase.

  Molecular pharmacology 20080901

• Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells.

  Blood 20080901

• Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir.

  Protein science : a publication of the Protein Society 20080901

• Effects of a selective serotonin reuptake inhibitor, fluoxetine, on counterregulatory responses to hypoglycemia in healthy individuals.

  Diabetes 20080901

• Alternative splicing of the Ca2+ channel beta4 subunit confers specificity for gabapentin inhibition of Cav2.1 trafficking.

  Molecular pharmacology 20080901

• Dehydroalanine and lysinoalanine in thermolyzed casein do not promote colon cancer in the rat.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080901

• Identification and characterization of CaApe2--a neutral arginine/alanine/leucine-specific metallo-aminopeptidase from Candida albicans.

  FEMS yeast research 20080901

• Equilibrated diet restores the effects of early age choline-deficient feeding on rat brain antioxidant status and enzyme activities: the role of homocysteine, L-phenylalanine and L-alanine.

  Metabolic brain disease 20080901

• Manganese superoxide dismutase Ala16Val polymorphism is associated with the development of type 2 diabetes in Japanese-Americans.

  Diabetes research and clinical practice 20080901

• Evaluation of lactate and alanine as metabolic biomarkers of prostate cancer using 1H HR-MAS spectroscopy of biopsy tissues.

  Magnetic resonance in medicine 20080901

• Inflammatory cytokines induce phosphorylation and ubiquitination of prostate suppressor protein NKX3.1.

  Cancer research 20080901

• Rebamipide as an important adjunctive tool in the management of rheumatologic disorders: comment on the article by Kohashi et al.

  Arthritis and rheumatism 20080901

• Modulation of cystathionine beta-synthase activity by the Arg-51 and Arg-224 mutations.

  Bioscience, biotechnology, and biochemistry 20080901

• The A98V single nucleotide polymorphism (SNP) in hepatic nuclear factor 1 alpha (HNF-1alpha) is associated with insulin sensitivity and beta-cell function.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20080901

• Kv1.5 open channel block by the antiarrhythmic drug disopyramide: molecular determinants of block.

  Journal of pharmacological sciences 20080901

• Genetic changes induced by the pesticide Ridomol in the soybeans sprouted from the seeds of different ages.

  Georgian medical news 20080901

• Molecule of the month. Semagacestat.

  Drug news & perspectives 20080901

• The phosphatidylinositol 3-kinase inhibitor LY 294002 inhibits GlyT1-mediated glycine uptake.

  Brain research 20080828

• Core level study of alanine and threonine.

  The journal of physical chemistry. A 20080828

• Effect of different wood pretreatments on the sorption-desorption of linuron and metalaxyl by woods.

  Journal of agricultural and food chemistry 20080827

• Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.

  Biochemistry 20080826

• Long-term prevention of Alzheimer's disease-like behavioral deficits in PDAPP mice carrying a mutation in Asp664.

  Behavioural brain research 20080822

• Beta-azidoalanine as an IR probe: application to amyloid Abeta(16-22) aggregation.

  The journal of physical chemistry. B 20080821

• Permeabilities of rebamipide via rat intestinal membranes and its colon specific delivery using chitosan capsule as a carrier.

  World journal of gastroenterology 20080821

• Probing structure-activity relationships in bactericidal peptide betapep-25.

  The Biochemical journal 20080815

• Organocatalytic asymmetric addition of alcohols and thiols to activated electrophiles: efficient dynamic kinetic resolution and desymmetrization protocols.

  The Journal of organic chemistry 20080815

• An intact connexin N-terminus is required for function but not gap junction formation.

  Journal of cell science 20080815

• Modeling the microhydration of protonated alanine.

  The journal of physical chemistry. B 20080814

• Stable supramolecular helical structure of C6-symmetric hydrogen-bonded hexakis(phenylethynyl)benzene derivatives with amino acid pendant groups and their unique fluorescence properties.

  Chemical communications (Cambridge, England) 20080807

• Metabolic changes during successful medical therapy for brain hydatid cyst: case report.

  Surgical neurology 20080801

• Characterisation of electrogenic nutrient absorption in the Cftr TgH(neoim)Hgu mouse model.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20080801

• Saturation transfer difference NMR studies on substrates and inhibitors of succinic semialdehyde dehydrogenases.

  Biochemical and biophysical research communications 20080801

• Electrochemical analysis of the alanine phenylthiohydantoin derivative by cathodic stripping voltammetry.

  Analytical biochemistry 20080801

• Indirect resolution of baclofen enantiomers from pharmaceutical dosage form by reversed-phase liquid chromatography after derivatization with Marfey's reagent and its structural variants.

  Biomedical chromatography : BMC 20080801

• Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles.

  Journal of virology 20080801

• Cooperative DNA binding and communication across the dimer interface in the TREX2 3' --> 5'-exonuclease.

  The Journal of biological chemistry 20080801

• The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma2 gene is associated with plasma levels of soluble RAGE (Receptor for Advanced Glycation Endproducts) and the presence of peripheral arterial disease.

  Clinical biochemistry 20080801

• The effect of initial concentration, co-application and repeated applications on pesticide degradation in a biobed mixture.

  Chemosphere 20080801

• Sugar-driven prebiotic synthesis of 3,5(6)-dimethylpyrazin-2-one: a possible nucleobase of a primitive replication process.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20080801

• Molecular interactions of alanine-rich and proline-rich regions of cell surface protein antigen c in Streptococcus mutans.

  Oral microbiology and immunology 20080801

• Synthesis and antitumor activity of cyclodepsipeptide zygosporamide and its analogues.

  Bioorganic & medicinal chemistry letters 20080801

• Synthesis and biological evaluation of a focused library of beauveriolides.

  Bioorganic & medicinal chemistry letters 20080801

• Transfection of the DAAO gene and subsequent induction of cytotoxic oxidative stress by D-alanine in 9L cells.

  Oncology reports 20080801

• Analysis of ethylenethiourea as a biomarker in human urine using liquid chromatography/triple quadrupole mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20080801

• Development of a temperature gradient focusing method for in situ extraterrestrial biomarker analysis.

  Electrophoresis 20080801

• Myocardial perfusion characteristics during machine perfusion for heart transplantation.

  Surgery 20080801

• Getting resourceful.

  Nature structural & molecular biology 20080801

• [Association of the Pro12Ala and C1431T polymorphism of the PPAR gamma2 gene and their haplotypes with obesity and type 2 diabetes].

  Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20080801

• Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease.

  Archives of neurology 20080801

• Cooperative transition between open and closed conformations in potassium channels.

  PLoS computational biology 20080801

• Over-expression of the potassium channel Kir2.3 using the dopamine-1 receptor promoter selectively inhibits striatal neurons.

  Neuroscience 20080731

• Helix forming tendency of valine substituted poly-alanine: a molecular dynamics investigation.

  The journal of physical chemistry. B 20080731

• Two novel alleles of tottering with distinct Ca(v)2.1 calcium channel neuropathologies.

  Neuroscience 20080731

• Conformational preferences and cis-trans isomerization of L-lactic acid residue.

  The journal of physical chemistry. B 20080731

• Disruption of agonist and ligand activity in an AMPA glutamate receptor splice-variable domain deletion mutant.

  Brain research 20080730

• A double role for a strictly conserved serine: further insights into the dUTPase catalytic mechanism.

  Biochemistry 20080729

• Mapping of the factor Xa binding site on factor Va by site-directed mutagenesis.

  The Journal of biological chemistry 20080725

• Alanine scanning of a putative receptor binding surface of insulin-like growth factor-I.

  The Journal of biological chemistry 20080725

• Substrate recognition of VAMP-2 by botulinum neurotoxin B and tetanus neurotoxin.

  The Journal of biological chemistry 20080725

• A novel photoactive GAF domain of cyanobacteriochrome AnPixJ that shows reversible green/red photoconversion.

  Journal of molecular biology 20080725

• Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1.

  Journal of molecular biology 20080725

• Molecular mechanism of Zn2+ agonism in the extracellular domain of GPR39.

  FEBS letters 20080723

• Protein kinase a mediates activity-dependent Kv4.2 channel trafficking.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080723

• Selective detection of uric acid in the presence of ascorbic acid at physiological pH by using a beta-cyclodextrin modified copolymer of sulfanilic acid and N-acetylaniline.

  Biosensors & bioelectronics 20080715

• Mutagenesis of the cysteine-rich clip domain in the Drosophila patterning protease, Snake.

  Archives of biochemistry and biophysics 20080715

• The importance of the leader sequence for directing lanthionine formation in lacticin 481.

  Biochemistry 20080715

• Sequence determinants of bacterial amyloid formation.

  Journal of molecular biology 20080711

• Anomalous dopamine release associated with a human dopamine transporter coding variant.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080709

• Rebamipide enema therapy for left-sided ischemic colitis patients accompanied by ulcers: open label study.

  World journal of gastroenterology 20080707

• New functional single nucleotide polymorphism (Ala72Ser) in the COMT gene is associated with aggressive behavior in male schizophrenia.

  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20080705

• Stereoselective synthesis of triply isotope-labeled Ser, Cys, and Ala: amino acids for stereoarray isotope labeling technology.

  Organic letters 20080703

• Non-agonist-binding subunit interfaces confer distinct functional signatures to the alternate stoichiometries of the alpha4beta2 nicotinic receptor: an alpha4-alpha4 interface is required for Zn2+ potentiation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080702

• Computational active site analysis of molecular pathways to improve functional classification of enzymes.

  Proteins 20080701

• The D-alanine content of lipoteichoic acid is crucial for Lactobacillus plantarum-mediated protection from visceral pain perception in a rat colorectal distension model.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080701

• Estrogen receptor-alpha hinge-region lysines 302 and 303 regulate receptor degradation by the proteasome.

  Molecular endocrinology (Baltimore, Md.) 20080701

• TNF-alpha-inducing protein, a carcinogenic factor secreted from H. pylori, enters gastric cancer cells.

  International journal of cancer 20080701

• In vivo alanine/electron spin resonance (ESR) dosimetry in radiotherapy of prostate cancer: a feasibility study.

  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20080701

• Requirement of Ala residues at g position in heptad sequence of alpha-helix-forming peptide for formation of fibrous structure.

  Journal of biochemistry 20080701

• Various routes of administration of (99m)Tc-labeled synthetic lactoferrin antimicrobial peptide hLF 1-11 enables monitoring and effective killing of multidrug-resistant Staphylococcus aureus infections in mice.

  Peptides 20080701

• Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein-protein recognition: application to the Bim BH3 domain.

  Protein science : a publication of the Protein Society 20080701

• Feasibility of using hyperpolarized [1-13C]lactate as a substrate for in vivo metabolic 13C MRSI studies.

  Magnetic resonance imaging 20080701

• Structural mobility of the monomeric C-terminal domain of the HIV-1 capsid protein.

  The FEBS journal 20080701

• Detection and identification of novel metabolomic biomarkers in preeclampsia.

  Reproductive sciences (Thousand Oaks, Calif.) 20080701

• The antiviral drug selected hepatitis B virus rtA181T/sW172* mutant has a dominant negative secretion defect and alters the typical profile of viral rebound.

  Hepatology (Baltimore, Md.) 20080701

• Critical molecular regions for elicitation of the sweetness of the sweet-tasting protein, thaumatin I.

  The FEBS journal 20080701

• An expert opinion on safinamide in Parkinson's disease.

  Expert opinion on investigational drugs 20080701

• Estimated H-atom anisotropic displacement parameters: a comparison between different methods and with neutron diffraction results.

  Acta crystallographica. Section A, Foundations of crystallography 20080701

• Complete covalent structure of nisin Q, new natural nisin variant, containing post-translationally modified amino acids.

  Bioscience, biotechnology, and biochemistry 20080701

• [A pilot study of rebamipide-gargle for chemoradiotherapy-induced mucositis in oral cancer patients].

  Gan to kagaku ryoho. Cancer & chemotherapy 20080701

• Crystalline degradation products of vancomycin as chiral stationary phase in microcolumn liquid chromatography.

  Journal of separation science 20080701

• K469E polymorphism of the intracellular adhesion molecule 1 gene is associated with proliferative diabetic retinopathy in Caucasians with type 2 diabetes.

  Clinical & experimental ophthalmology 20080701

• Construction of the free energy landscape of biomolecules via dihedral angle principal component analysis.

  The Journal of chemical physics 20080628

• Extended hormone binding site of the human thyroid stimulating hormone receptor: distinctive acidic residues in the hinge region are involved in bovine thyroid stimulating hormone binding and receptor activation.

  The Journal of biological chemistry 20080627

• Study on physicochemical properties of ionic liquids based on alanine [Cnmim][Ala] (N=2,3,4,5,6).

  The journal of physical chemistry. B 20080626

• Phosphorylation and dephosphorylation of tyrosine 141 regulate stability and degradation of INrf2: a novel mechanism in Nrf2 activation.

  The Journal of biological chemistry 20080620

• The fluorescent amino acid p-cyanophenylalanine provides an intrinsic probe of amyloid formation.

  Chembiochem : a European journal of chemical biology 20080616

• Ribosomal synthesis of bicyclic peptides via two orthogonal inter-side-chain reactions.

  Journal of the American Chemical Society 20080611

• Structural and dynamical characterization of fibrils from a disease-associated alanine expansion domain using proteolysis and solid-state NMR spectroscopy.

  Journal of the American Chemical Society 20080611

• Alpha-Ca2+/calmodulin-dependent protein kinase II contributes to the developmental programming of anxiety in serotonin receptor 1A knock-out mice.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080611

• Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation.

  The Journal of biological chemistry 20080606

• Efficacy and tolerability of an mGlu2/3 agonist in the treatment of generalized anxiety disorder.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080601

• The polymorphisms Asn130Asp and Val174Ala in OATP1B1 and the CYP2C9 allele *3 independently affect torsemide pharmacokinetics and pharmacodynamics.

  Clinical pharmacology and therapeutics 20080601

• Formation of Fmoc-beta-alanine during Fmoc-protections with Fmoc-OSu.

  Journal of peptide science : an official publication of the European Peptide Society 20080601

• Proteasomes remain intact, but show early focal alteration in their composition in a mouse model of amyotrophic lateral sclerosis.

  Journal of neurochemistry 20080601

• Insights into homonuclear decoupling from efficient numerical simulation: techniques and examples.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20080601

• Rebampide enema therapy as a treatment for patients with chronic radiation proctitis: initial treatment or when other methods of conservative management have failed.

  International journal of colorectal disease 20080601

• Definition of a conserved immunodominant domain on hepatitis C virus E2 glycoprotein by neutralizing human monoclonal antibodies.

  Journal of virology 20080601

• Molecular basis of perinatal hypophosphatasia with tissue-nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406. Structural importance of the crown domain.

  The FEBS journal 20080601

• Role of disulfide bonds in goose-type lysozyme.

  The FEBS journal 20080601

• Effect of potassium citrate salts on the vapor-liquid equilibrium properties of aqueous solutions of alanine at different temperatures.

  Biophysical chemistry 20080601

• Modulation of self-association and subsequent fibril formation in an alanine-rich helical polypeptide.

  Biomacromolecules 20080601

• Early and sustained alterations in cerebral metabolism after traumatic brain injury in immature rats.

  Journal of neurotrauma 20080601

• Verification of the C-terminal intramolecular beta-sheet in Abeta42 aggregates using solid-state NMR: implications for potent neurotoxicity through the formation of radicals.

  Bioorganic & medicinal chemistry letters 20080601

• Quantitation with QUEST of brain HRMAS-NMR signals: application to metabolic disorders in experimental epileptic seizures.

  Magnetic resonance in medicine 20080601

• Concerted modulation of alanine and glutamate metabolism in young Medicago truncatula seedlings under hypoxic stress.

  Journal of experimental botany 20080601

• Slow desiccation improves dehydration tolerance and accumulation of compatible osmolytes in earthworm cocoons (Dendrobaena octaedra Savigny).

  The Journal of experimental biology 20080601

• Increased D-alanylation of lipoteichoic acid and a thickened septum are main determinants in the nisin resistance mechanism of Lactococcus lactis.

  Microbiology (Reading, England) 20080601

• Fusion of Epstein-Barr virus nuclear antigen-1-derived glycine-alanine repeat to trans-dominant HIV-1 Gag increases inhibitory activities and survival of transduced cells in vivo.

  Human gene therapy 20080601

• High-throughput nuclear magnetic resonance metabolomic footprinting for tissue engineering.

  Tissue engineering. Part C, Methods 20080601

• Mitochondrial diseases mimicking neurotransmitter defects.

  Mitochondrion 20080601

• Biochemical alterations from normal mucosa to gastric cancer by ex vivo magnetic resonance spectroscopy.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080601

• Investigating compensation and recovery of fathead minnow (Pimephales promelas) exposed to 17alpha-ethynylestradiol with metabolite profiling.

  Environmental science & technology 20080601

• Neurometabolic effects of ACTH on free amino compounds in opsoclonus-myoclonus syndrome.

  Neuropediatrics 20080601

• Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy.

  Circulation. Arrhythmia and electrophysiology 20080601

• Synthesis of a novel fluorescent probe based on acridine skeleton used for sensitive determination of DNA.

  Talanta 20080530

• Copper(II) 12-metallacrown-4 complexes of alpha-, beta- and gamma-aminohydroxamic acids: a comparative thermodynamic study in aqueous solution.

  Dalton transactions (Cambridge, England : 2003) 20080528

• The role of the conserved switch II glutamate in guanine nucleotide exchange factor-mediated nucleotide exchange of GTP-binding proteins.

  Journal of molecular biology 20080523

• Response of the alanine/ESR dosimetry system to MV X-rays relative to (60)Co radiation.

  Physics in medicine and biology 20080521

• Expansion of substrate specificity and catalytic mechanism of azoreductase by X-ray crystallography and site-directed mutagenesis.

  The Journal of biological chemistry 20080516

• Neurochemical effects of the monoamine oxidase inhibitor phenelzine on brain GABA and alanine: A comparison with vigabatrin.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20080516

• The point mutation A34F causes dimerization of GB1.

  Proteins 20080515

• Atypical early-onset Alzheimer's disease caused by the Iranian APP mutation.

  Journal of the neurological sciences 20080515

• Mutational analysis of conserved glycine residues 142, 143 and 146 reveals Gly(142) is critical for tetramerization of CTP synthase from Escherichia coli.

  The Biochemical journal 20080515

• A differential fluctuation theorem.

  The journal of physical chemistry. B 20080515

• Human metabolic phenotype diversity and its association with diet and blood pressure.

  Nature 20080515

• Monitoring fibril formation of the N-terminal domain of PABPN1 carrying an alanine repeat by tryptophan fluorescence and real-time NMR.

  FEBS letters 20080514

• Single-sweep methods for free energy calculations.

  The Journal of chemical physics 20080514

• Molecular dynamics simulation study on stabilities and reactivities of NADH cytochrome B5 reductase.

  The journal of physical chemistry. B 20080508

• Preparation and comprehensive characterization of [Hg6(alanine)4(NO3)4].H2O.

  Inorganic chemistry 20080505

• Highly conserved asparagine 82 controls the interaction of Na+ with the sodium-coupled neutral amino acid transporter SNAT2.

  The Journal of biological chemistry 20080502

• Isolated cytochrome c oxidase deficiency in G93A SOD1 mice overexpressing CCS protein.

  The Journal of biological chemistry 20080502

• NMR spectroscopy of the ligand-binding core of ionotropic glutamate receptor 2 bound to 5-substituted willardiine partial agonists.

  Journal of molecular biology 20080502

• Structure-activity relationships of urotensin II and URP.

  Peptides 20080501

• Sucrose radical-production cross-section regarding heavy-ion irradiation.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080501

• The effect of dose on light-sensitivity of radicals in alanine EPR dosimeters.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080501

• EPR spectra of gamma-irradiated DL-alpha-alanine supported on molecular sieves.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080501

• Functional and structural roles of conserved cysteine residues in the carboxyl-terminal domain of the follicle-stimulating hormone receptor in human embryonic kidney 293 cells.

  Biology of reproduction 20080501

• Clinical features and mutational survey of NPHS2 (podocin) in Japanese children with focal segmental glomerulosclerosis who underwent renal transplantation.

  Pediatric transplantation 20080501

• Diverse roles of glycine residues conserved in photoactive yellow proteins.

  Biophysical journal 20080501

• A new method for ligand docking to flexible receptors by dual alanine scanning and refinement (SCARE).

  Journal of computer-aided molecular design 20080501

• Tissue inhibitor of metalloproteinases-3 (TIMP-3) expression is increased during serum deprivation-induced neuronal apoptosis in vitro and in the G93A mouse model of amyotrophic lateral sclerosis: a potential modulator of Fas-mediated apoptosis.

  Neurobiology of disease 20080501

• Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda.

  EMBO reports 20080501

• TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis.

  The Lancet. Neurology 20080501

• Photomodulated chiral induction in helical azobenzene oligomers.

  Organic letters 20080501

• Physicochemical properties and microstructure formation of the surfactant mixtures of sodium N-(2-(n-dodecylamino)ethanoyl)-L-alaninate and SDS in aqueous solutions.

  The journal of physical chemistry. B 20080501

• Homozygous mutation of the PHOX2B gene in congenital central hypoventilation syndrome (Ondine's Curse).

  Human mutation 20080501

• Dentin phosphophoryn promotes cellular migration of human dental pulp cells.

  Journal of endodontics 20080501

• GS-9219--a novel acyclic nucleotide analogue with potent antineoplastic activity in dogs with spontaneous non-Hodgkin's lymphoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080501

• Determination of the orientations for the 17O NMR tensors in a polycrystalline l-alanine hydrochloride.

  Solid state nuclear magnetic resonance 20080501

• Rerouting the folding pathway of the Notch ankyrin domain by reshaping the energy landscape.

  Journal of the American Chemical Society 20080430

• Identification of residues contributing to A2 domain-dependent structural stability in factor VIII and factor VIIIa.

  The Journal of biological chemistry 20080425

• Physical gelation of binary mixtures of hydrocarbons mediated by n-lauroyl-L-alanine and characterization of their thermal and mechanical properties.

  The journal of physical chemistry. B 20080424

• Identification of critical residues for G-1 addition and substrate recognition by tRNA(His) guanylyltransferase.

  Biochemistry 20080422

• Characterization of ligand-binding properties of the human BMP type II receptor extracellular domain.

  Journal of molecular biology 20080418

• Facile conversion of cysteine and alkyl cysteines to dehydroalanine on protein surfaces: versatile and switchable access to functionalized proteins.

  Journal of the American Chemical Society 20080416

• Transthyretin Ala97Ser in Chinese-Taiwanese patients with familial amyloid polyneuropathy: genetic studies and phenotype expression.

  Journal of the neurological sciences 20080415

• A glia-neuron alanine/ammonium shuttle is central to energy metabolism in bee retina.

  The Journal of physiology 20080415

• Alanine scanning mutagenesis of anti-TRAP (AT) reveals residues involved in binding to TRAP.

  Journal of molecular biology 20080411

• Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta3-hPhe-beta3-hAla-NHMe and Ac-beta3-hAla-beta3-hPhe-NHMe.

  Journal of the American Chemical Society 20080409

• Role of helix B residues in interfacial activation of a bacterial phosphatidylinositol-specific phospholipase C.

  Biochemistry 20080408

• Formation of molecular glasses and the aggregation in solutions for lanthanum(III), calcium(II), and yttrium(III) complexes of octanoyl-DL-alaninate.

  Dalton transactions (Cambridge, England : 2003) 20080407

• A new type of soft vesicle-forming molecule: an amino acid derived guanidiniocarbonyl pyrrole carboxylate zwitterion.

  Organic letters 20080403

• The LOC387715 polymorphism, inflammatory markers, smoking, and age-related macular degeneration. A population-based case-control study.

  Ophthalmology 20080401

• Glutamine protects against increases in blood ammonia in football players in an exercise intensity-dependent way.

  British journal of sports medicine 20080401

• The interaction of arginine- and tryptophan-rich cyclic hexapeptides with Escherichia coli membranes.

  Journal of peptide science : an official publication of the European Peptide Society 20080401

• Cysteine 10 is critical for the activity of Ochrobactrum anthropi glutathione transferase and its mutation to alanine causes the preferential binding of glutathione to the H-site.

  Proteins 20080401

• Alanine variant of the Pro12Ala polymorphism of the PPARgamma gene might be associated with decreased risk of diabetic retinopathy in type 2 diabetes.

  Diabetes research and clinical practice 20080401

• The aroma side of the Maillard reaction.

  Annals of the New York Academy of Sciences 20080401

• The effect of single and repeated UVB radiation on rabbit lens.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20080401

• Intraportal administration of neuropeptide Y and hepatic glucose metabolism.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080401

• Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity.

  The FEBS journal 20080401

• TDP-43 A315T mutation in familial motor neuron disease.

  Annals of neurology 20080401

• New dicholesteryl-based gelators: chirality and spacer length effect.

  Langmuir : the ACS journal of surfaces and colloids 20080401

• Effect of OPC-12759 on EGF receptor activation, p44/p42 MAPK activity, and secretion in conjunctival goblet cells.

  Experimental eye research 20080401

• Increasing permeability of phospholipid bilayer membranes to alanine with synthetic alpha-aminophosphonate carriers.

  Bioorganic & medicinal chemistry letters 20080401

• Natural occurrence of microcystin synthetase deletion mutants capable of producing microcystins in strains of the genus Anabaena (Cyanobacteria).

  Microbiology (Reading, England) 20080401

• Vulnerability of gastric mucosa to prednisolone in rats chronically exposed to cigarette smoke.

  Journal of pharmacological sciences 20080401

• Parental obesity and offspring serum alanine and aspartate aminotransferase levels: the Framingham heart study.

  Gastroenterology 20080401

• Crystal structure of the CaV2 IQ domain in complex with Ca2+/calmodulin: high-resolution mechanistic implications for channel regulation by Ca2+.

  Structure (London, England : 1993) 20080401

• [Distribution of free D-amino acids and their biosyntheses and physiological roles in aquatic animals].

  Seikagaku. The Journal of Japanese Biochemical Society 20080401

• Discovery of brivanib alaninate ((S)-((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-yl)2-aminopropanoate), a novel prodrug of dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 kinase inhibitor (BMS-540215).

  Journal of medicinal chemistry 20080327

• Functional characterization of tyrosine transport in fibroblast cells from healthy controls.

  Neuroscience letters 20080321

• Finding transition pathways using the string method with swarms of trajectories.

  The journal of physical chemistry. B 20080320

• Kinetic and mechanistic analysis of Trypanosoma cruzi trans-sialidase reveals a classical ping-pong mechanism with acid/base catalysis.

  Biochemistry 20080318

• Adsorption of alpha amino acids at the water/goethite interface.

  Journal of colloid and interface science 20080315

• Transfer RNA modulates the editing mechanism used by class II prolyl-tRNA synthetase.

  The Journal of biological chemistry 20080314

• Analysis of the thermodynamics of binding of an SH3 domain to proline-rich peptides using a chimeric fusion protein.

  Journal of molecular biology 20080314

• RecA-dependent cleavage of LexA dimers.

  Journal of molecular biology 20080314

• Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency.

  Journal of medicinal chemistry 20080313

• Antibody recognition and conformational flexibility of a plaque-specific beta-amyloid epitope modulated by non-native peptide flanking regions.

  Journal of medicinal chemistry 20080313

• Postirradiation effects in alanine dosimeter probes of two different suppliers.

  Physics in medicine and biology 20080307

• Cellular origin of dysiherbaine, an excitatory amino acid derived from a marine sponge.

  Chembiochem : a European journal of chemical biology 20080303

• Advances in solid alanine radiolysis understanding.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080301

• Lack of association between the Pro12Ala polymorphism of the PPAR-gamma 2 gene and type 2 diabetes mellitus in the Qatari consanguineous population.

  Acta diabetologica 20080301

• Conformational studies of alanine-rich peptide using CD and FTIR spectroscopy.

  Journal of peptide science : an official publication of the European Peptide Society 20080301

• Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors.

  Molecular pharmacology 20080301

• Molecular cloning and functional characterization of porcine nucleotide-binding oligomerization domain-1 (NOD1) recognizing minimum agonists, meso-diaminopimelic acid and meso-lanthionine.

  Molecular immunology 20080301

• F413C and A531V but not R894X myotonia congenita mutations cause defective endoplasmic reticulum export of the muscle-specific chloride channel CLC-1.

  Muscle & nerve 20080301

• Combined effect of the DeltaPhe or DeltaAla residue and the p-nitroanilide group on a didehydropeptides conformation.

  Biopolymers 20080301

• Identification and characterization of two amino acids critical for the substrate inhibition of human dehydroepiandrosterone sulfotransferase (SULT2A1).

  Molecular pharmacology 20080301

• Homozygosity for mutation G212A of the gene for aspartoacylase is associated with atypical form of Canavan's disease.

  Clinical genetics 20080301

• Requirement of beta-alanine components in sequence-specific DNA alkylation by pyrrole-imidazole conjugates with seven-base pair recognition.

  Bioorganic & medicinal chemistry 20080301

• Different brain responses to hypoglycemia induced by equipotent doses of the long-acting insulin analog detemir and human regular insulin in humans.

  Diabetes 20080301

• Staphylococcus aureus MurC participates in L-alanine recognition via histidine 343, a conserved motif in the shallow hydrophobic pocket.

  Journal of biochemistry 20080301

• Genome-scale analysis of anti-metabolite directed strain engineering.

  Metabolic engineering 20080301

• Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol.

  Archives of biochemistry and biophysics 20080301

• Fjord-region benzo[g]chrysene-11,12-dihydrodiol and benzo[c]phenanthrene-3,4-dihydrodiol as substrates for rat liver dihydrodiol dehydrogenase (AKR1C9): structural basis for stereochemical preference.

  Chemical research in toxicology 20080301

• Low micromolar concentrations of cadmium and mercury ions activate peritubular membrane K+ conductance in proximal tubular cells of frog kidney.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20080301

• Characterization of gastrin-cholecystokinin 2 receptor interaction in relation to c-fos induction.

  Endocrine-related cancer 20080301

• Substitution of only two residues of human Hsp90alpha causes impeded dimerization of Hsp90beta.

  Cell stress & chaperones 20080301

• Prophylactic effect of rebamipide on aspirin-induced gastric lesions and disruption of tight junctional protein zonula occludens-1 distribution.

  Journal of pharmacological sciences 20080301

• Elevated gluconeogenesis and lack of suppression by insulin contribute to cystic fibrosis-related diabetes.

  Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20080301

• [The gerA operon is required for spore germination in Bacillus thuringiensis].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20080301

• [Permeabilities of rebamipide via different intestinal mucosa in the diffusion chamber in vitro].

  Yao xue xue bao = Acta pharmaceutica Sinica 20080301

• Separation of racemate from excess enantiomer of chiral nonracemic compounds via density gradient ultracentrifugation.

  Journal of the American Chemical Society 20080227

• Age-dependent dichotomous effect of superoxide dismutase Ala16Val polymorphism on oxidized LDL levels.

  Experimental & molecular medicine 20080227

• Congenital hypersensitivity to vitamin K antagonists due to FIX propeptide mutation at locus -10: a (not so) rare cause of bleeding under oral anticoagulant therapy in Switzerland.

  Swiss medical weekly 20080223

• Investigating alanine-silica interaction by means of first-principles molecular-dynamics simulations.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20080222

• Synthesis and testing of chromogenic phenoxazinone substrates for beta-alanyl aminopeptidase.

  Organic & biomolecular chemistry 20080221

• Fragmentation of alpha- and beta-alanine molecules by ions at Bragg-peak energies.

  The Journal of chemical physics 20080221

• Hofmeister salts and potential therapeutic compounds accelerate in vitro fibril formation of the N-terminal domain of PABPN1 containing a disease-causing alanine extension.

  Biochemistry 20080219

• Mutagenesis study of rice nonspecific lipid transfer protein 2 reveals residues that contribute to structure and ligand binding.

  Proteins 20080215

• Residual structure in disordered peptides and unfolded proteins from multivariate analysis and ab initio simulation of Raman optical activity data.

  Proteins 20080215

• Trapping of an acyl-enzyme intermediate in a penicillin-binding protein (PBP)-catalyzed reaction.

  Journal of molecular biology 20080215

• Molecular basis for the unique deubiquitinating activity of the NF-kappaB inhibitor A20.

  Journal of molecular biology 20080215

• mRNA decapping is promoted by an RNA-binding channel in Dcp2.

  Molecular cell 20080215

• Structural basis of dcp2 recognition and activation by dcp1.

  Molecular cell 20080215

• Volumetric properties of the glycyl group of proteins in aqueous solution at high pressures.

  Physical chemistry chemical physics : PCCP 20080214

• Comprehensive analysis of the factors contributing to the stability and solubility of autonomous human VH domains.

  The Journal of biological chemistry 20080208

• Simulating temperature jumps for protein folding.

  The journal of physical chemistry. B 20080207

• Electron transfer and electrocatalytic properties of the immobilized methionine80alanine cytochrome c variant.

  The journal of physical chemistry. B 20080207

• When is a molecule properly solvated by a continuum model or in a cluster ansatz? A first-principles simulation of alanine hydration.

  The journal of physical chemistry. B 20080207

• Potentiation of the NMDA receptor in the treatment of schizophrenia: focused on the glycine site.

  European archives of psychiatry and clinical neuroscience 20080201

• Rebamipide, anti-gastric ulcer drug, up-regulates the induction of iNOS in proinflammatory cytokine-stimulated hepatocytes.

  Nitric oxide : biology and chemistry 20080201

• Interactions between loop 5 and beta-strand beta6' are involved in alpha7 nicotinic acetylcholine receptors channel gating.

  Journal of neurochemistry 20080201

• Influence of the sporulation temperature on the impact of the nutrients inosine and l-alanine on Bacillus cereus spore germination.

  Food microbiology 20080201

• A mutagenesis strategy combining systematic alanine scanning with larger mutations to study protein interactions.

  Analytical biochemistry 20080201

• Novel analogs and stereoisomers of the marine toxin neodysiherbaine with specificity for kainate receptors.

  The Journal of pharmacology and experimental therapeutics 20080201

• In vitro antimicrobial and in vivo antioomycete activities of the novel antibiotic thiobutacin.

  Pest management science 20080201

• The interaction domains of the plant Myc-like bHLH transcription factors can regulate the transactivation strength.

  Planta 20080201

• Stereoselective degradation of benalaxyl in tomato, tobacco, sugar beet, capsicum, and soil.

  Chirality 20080201

• 1H NMR-based metabolomic analysis of liver, serum, and brain following ethanol administration in rats.

  Chemical research in toxicology 20080201

• Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1.

  Journal of molecular biology 20080201

• A new twist in TCR diversity revealed by a forbidden alphabeta TCR.

  Journal of molecular biology 20080201

• Improvement of the cold storage of blood vessels with a vascular preservation solution. Study in porcine aortic segments.

  Journal of vascular surgery 20080201

• 3-Aminopyrrolidines from alpha-aminoacids: total synthesis of (+)-nemonapride from D-alanine.

  The Journal of organic chemistry 20080201

• Peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism, cod liver oil and risk of type 1 diabetes.

  Pediatric diabetes 20080201

• The Effect of gadolinium on the ESR response of alanine and ammonium tartrate exposed to thermal neutrons.

  Radiation research 20080201

• Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets.

  Journal of pediatric gastroenterology and nutrition 20080201

• Properties of serine:glyoxylate aminotransferase purified from Arabidopsis thaliana leaves.

  Acta biochimica et biophysica Sinica 20080201

• Effective treatment with oral administration of rebamipide in a mouse model of Sjögren's syndrome.

  Arthritis and rheumatism 20080201

• Alanine-scanning mutagenesis defines a conserved energetic hotspot in the CaValpha1 AID-CaVbeta interaction site that is critical for channel modulation.

  Structure (London, England : 1993) 20080201

• A review of telavancin in the treatment of complicated skin and skin structure infections (cSSSI).

  Therapeutics and clinical risk management 20080201

• Quasiplanarity of the peptide bond.

  The journal of physical chemistry. A 20080131

• Identifying the presence of a disulfide linkage in peptides by the selective elimination of hydrogen disulfide from collisionally activated alkali and alkaline earth metal complexes.

  Journal of the American Chemical Society 20080130

• Measures to reduce pesticide spray drift in a small aquatic ecosystem in vineyard estate.

  The Science of the total environment 20080125

• Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins.

  Journal of molecular biology 20080125

• Processing of N-terminal unnatural amino acids in recombinant human interferon-beta in Escherichia coli.

  Chembiochem : a European journal of chemical biology 20080125

• The role of the conserved threonine in P450 BM3 oxygen activation: substrate-determined hydroxylation activity of the Thr268Ala mutant.

  Chembiochem : a European journal of chemical biology 20080125

• Mechanism of IS200/IS605 family DNA transposases: activation and transposon-directed target site selection.

  Cell 20080125

• Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185.

  Cell 20080125

• Functional activity of a large neutral amino acid transporter (LAT) in rabbit retina: a study involving the in vivo retinal uptake and vitreal pharmacokinetics of L-phenyl alanine.

  International journal of pharmaceutics 20080122

• The Escherichia coli TatABC system and a Bacillus subtilis TatAC-type system recognise three distinct targeting determinants in twin-arginine signal peptides.

  Journal of molecular biology 20080118

• Structural insight into the specific interaction between murine SHPS-1/SIRP alpha and its ligand CD47.

  Journal of molecular biology 20080118

• Predicting the effect of a point mutation on a protein fold: the villin and advillin headpieces and their Pro62Ala mutants.

  Journal of molecular biology 20080111

• Two- and three-dimensional smectic ordering of single-handed helical polymers.

  Journal of the American Chemical Society 20080109

• Genetic polymorphism in the manganese superoxide dismutase gene is associated with an increased risk for hepatocellular carcinoma in HCV-infected Moroccan patients.

  Mutation research 20080108

• Chemical interplay in the mechanism of partial agonist activation in alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.

  Biochemistry 20080108

• Positively charged microemulsions for topical application.

  International journal of pharmaceutics 20080104

• Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism.

  The Journal of biological chemistry 20080104

• Structural basis for catalysis by onconase.

  Journal of molecular biology 20080104

• XylS-Pm promoter interactions through two helix-turn-helix motifs: identifying XylS residues important for DNA binding and activation.

  Journal of molecular biology 20080104

• Rapid and efficient synthesis of dysiherbaine and analogues to explore structure-activity relationships.

  The Journal of organic chemistry 20080104

• Density functional theory guided design of exo-selective dehydroalanine dienophiles for application toward the synthesis of palau'amine.

  The Journal of organic chemistry 20080104

• PPAR-gamma Pro12Ala genotype and risk of cognitive decline in elders.

  Neurobiology of aging 20080101

• Computational alanine scanning and free energy decomposition for E. coli type I signal peptidase with lipopeptide inhibitor complex.

  Journal of molecular graphics & modelling 20080101

• The m.5650G>A mitochondrial tRNAAla mutation is pathogenic and causes a phenotype of pure myopathy.

  Neuromuscular disorders : NMD 20080101

• Formation of diacetyl and acetoin by Lactococcus lactis via aspartate catabolism.

  Journal of applied microbiology 20080101

• The N-terminal region of ABC50 interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2.

  The Biochemical journal 20080101

• Mutational analysis of the FXNPXY motif within LDL receptor-related protein 1 (LRP1) reveals the functional importance of the tyrosine residues in cell growth regulation and signal transduction.

  The Biochemical journal 20080101

• Multiple superoxide dismutase 1/splicing factor serine alanine 15 variants are associated with the development and progression of diabetic nephropathy: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Genetics study.

  Diabetes 20080101

• Coherence transfer between spy nuclei and nitrogen-14 in solids.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20080101

• The M129V polymorphism of codon 129 in the prion gene (PRNP) in the Danish population.

  European journal of epidemiology 20080101

• Proposed cycles for functional glutamate trafficking in synaptic neurotransmission.

  Neurochemistry international 20080101

• Experimental determination of orientations for the 17 O electric-field-gradient and chemical shielding tensors in L-alanine.

  Solid state nuclear magnetic resonance 20080101

• Amavadin and other vanadium complexes as remarkably efficient catalysts for one-pot conversion of ethane to propionic and acetic acids.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Contribution of the GABA shunt to hypoxia-induced alanine accumulation in roots of Arabidopsis thaliana.

  Plant & cell physiology 20080101

• Comparative properties of insulin-like growth factor 1 (IGF-1) and [Gly7D-Ala]IGF-1 prepared by total chemical synthesis.

  Angewandte Chemie (International ed. in English) 20080101

• Na+-dependent neutral amino acid transporter ASCT2 is downregulated in seriously traumatized human intestinal epithelial cells.

  Journal of pediatric gastroenterology and nutrition 20080101

• Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1.

  The European journal of neuroscience 20080101

• Using peptides to study the interaction between the p53 tetramerization domain and HIV-1 Tat.

  Biopolymers 20080101

• An unstable targeted allele of the mouse Mitf gene with a high somatic and germline reversion rate.

  Genetics 20080101

• Dehydroalanine derived from cysteine is a common post-translational modification in human serum albumin.

  Rapid communications in mass spectrometry : RCM 20080101

• Alanine in HI: a silent mutation cries out!

  Advances in experimental medicine and biology 20080101

• Effect of N-chloroamino acids on the erythrocyte.

  Free radical research 20080101

• Stabilization of beta-propeller phytase by introducing Xaa-->Pro and Gly-->Ala substitutions at consensus positions.

  Protein and peptide letters 20080101

• Dynamics change of phoborhodopsin and transducer by activation: study using D75N mutant of the receptor by site-directed solid-state 13C NMR.

  Photochemistry and photobiology 20080101

• Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged-to-alanine-scanning mutagenesis.

  International journal of hematology 20080101

• Low-temperature spectroscopy of Met100Ala mutant of photoactive yellow protein.

  Photochemistry and photobiology 20080101

• Mutation detection using ENDO1: application to disease diagnostics in humans and TILLING and Eco-TILLING in plants.

  BMC molecular biology 20080101

• Separation and measurement of plant alkaloid enantiomers by RP-HPLC analysis of their Fmoc-Alanine analogs.

  Phytochemical analysis : PCA 20080101

• Biophysical characterization of the recombinant merozoite surface protein-3 of Plasmodium vivax.

  Biochimica et biophysica acta 20080101

• Efficacy of rebamipide for diclofenac-induced small-intestinal mucosal injuries in healthy subjects: a prospective, randomized, double-blinded, placebo-controlled, cross-over study.

  Journal of gastroenterology 20080101

• Synthesis of two peptide mimetics as markers for chemical changes of wool's keratin during skin unhairing process.

  Protein and peptide letters 20080101

• The GraRS regulatory system controls Staphylococcus aureus susceptibility to antimicrobial host defenses.

  BMC microbiology 20080101

• Enhanced transdermal delivery of a dipeptide by dermaportation.

  Biopolymers 20080101

• Preclinical studies of steroid-linked nitrosoureas in murine pancreatic adenocarcinoma PANO2.

  Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20080101

• Microbial detoxification of metalaxyl in aquatic system.

  Journal of environmental sciences (China) 20080101

• Acidic-basic properties of three alanine-based peptides containing acidic and basic side chains: comparison between theory and experiment.

  Biopolymers 20080101

• Triazole-linked host compounds for chiral-discrimination toward amino acid ester guests.

  Journal of oleo science 20080101

• Influence of charge and size of terminal amino-acid residues on local conformational states and shape of alanine-based peptides.

  Biopolymers 20080101

• Mechanism of chiral-selective tRNA aminoacylation and the origin of amino acid homochirality.

  Nucleic acids symposium series (2004) 20080101

• Staphylococcus epidermidis: a differential trait of the fecal microbiota of breast-fed infants.

  BMC microbiology 20080101

• Efficient inhibition of murine breast cancer growth and metastasis by gene transferred mouse survivin Thr34-->Ala mutant.

  Journal of experimental & clinical cancer research : CR 20080101

• Specific JNK inhibition by D-JNKI1 protects Purkinje cells from cell death in Lurcher mutant mouse.

  Cerebellum (London, England) 20080101

• A new mutation in BFSP2 (G1091A) causes autosomal dominant congenital lamellar cataracts.

  Molecular vision 20080101

• [Acyclic nucleoside phosphonates as potential antineoplastic agents].

  Casopis lekaru ceskych 20080101

• Compstatin: a complement inhibitor on its way to clinical application.

  Advances in experimental medicine and biology 20080101

• Two new hemoglobin variants: Hb Sinai-Greenspring [beta34(B16)Val-->Ile, GTC > ATC] and Hb Sinai-Bel Air [beta53(D4)Ala-->Asp, GCT > GAT].

  Hemoglobin 20080101

• A highly conserved alanine in the S6 domain of the hERG1 K+ channel is required for normal gating.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

• [Scaffolds based on collagen and chitosan for post-burn tissue engineering].

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20080101

• The association of Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma gene with serum osteoprotegerin levels in healthy Korean women.

  Experimental & molecular medicine 20071231

• Role of the epsilon subunit of thermophilic F1-ATPase as a sensor for ATP.

  The Journal of biological chemistry 20071228

• Helix formation inside a nanotube: possible influence of backbone-water hydrogen bonding by the confining surface through modulation of water activity.

  The Journal of chemical physics 20071228

• Facile stereospecific synthesis and biological evaluation of (S)- and (R)-2-amino-2-methyl-4-[123I]iodo-3-(E)-butenoic acid for brain tumor imaging with single photon emission computerized tomography.

  Journal of medicinal chemistry 20071227

• Expression and purification of a Plasmodium vivax antigen - PvTARAg55 tryptophan- and alanine-rich antigen and its immunological responses in human subjects.

  Vaccine 20071221

• A new labeling method for methyl transverse relaxation-optimized spectroscopy NMR spectra of alanine residues.

  Journal of the American Chemical Society 20071219

• Early onset progressive ataxia associated with the first CACNA1A mutation identified within the I-II loop.

  Journal of the neurological sciences 20071215

• Brain metabolite abnormalities in the white matter of elderly schizophrenic subjects: implication for glial dysfunction.

  Biological psychiatry 20071215

• Intrathecal injection of glutamate receptor antagonists/agonist selectively attenuated rat pain-related behaviors induced by the venom of scorpion Buthus martensi Karsch.

  Toxicon : official journal of the International Society on Toxinology 20071215

• Rod1, an arrestin-related protein, is phosphorylated by Snf1-kinase in Saccharomyces cerevisiae.

  Biochemical and biophysical research communications 20071214

• Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression.

  Science (New York, N.Y.) 20071214

• Competition between the ATPase Prp5 and branch region-U2 snRNA pairing modulates the fidelity of spliceosome assembly.

  Molecular cell 20071214

• Role of the amino acid invariants in the active site of MurG as evaluated by site-directed mutagenesis.

  Biochimie 20071201

• Myristic acid increases the activity of dihydroceramide Delta4-desaturase 1 through its N-terminal myristoylation.

  Biochimie 20071201

• Evaluation of thyroid hormone action in a case of generalized resistance to thyroid hormone with chronic thyroiditis: discovery of a novel heterozygous missense mutation (G347A).

  Endocrine journal 20071201

• The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obesity-related traits in the Diabetes Prevention Program.

  Diabetologia 20071201

• Quantitative measurements of vancomycin binding to self-assembled peptide monolayers on chips by quartz crystal microbalance.

  Analytical biochemistry 20071201

• Interaction between murine spf-ash mutation and genetic background yields different metabolic phenotypes.

  American journal of physiology. Endocrinology and metabolism 20071201

• Oxindolealanine in age-related human cataracts.

  Experimental eye research 20071201

• The MnSOD Val9Ala polymorphism, dietary antioxidant intake, risk and survival in ovarian cancer (Australia).

  Gynecologic oncology 20071201

• Assessment of the genotoxicity of imidacloprid and metalaxyl in cultured human lymphocytes and rat bone-marrow.

  Mutation research 20071201

• Transthyretin valine-94-alanine, a novel variant associated with late-onset systemic amyloidosis with cardiac involvement.

  Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20071201

• Use of NMR metabolomics to analyze the targets of D-cycloserine in mycobacteria: role of D-alanine racemase.

  Journal of proteome research 20071201

• Haemostatic genetic variants, ABO blood group and bleeding risk during oral anticoagulant treatment after cerebral ischaemia of arterial origin.

  Journal of neurology 20071201

• Disruption of dopamine homeostasis underlies selective neurodegeneration mediated by alpha-synuclein.

  The European journal of neuroscience 20071201

• Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor gamma. Chief and corroborative hydrogen bonds of the bisphenol A phenol-hydroxyl group with Arg316 and Glu275 residues.

  The FEBS journal 20071201

• Biogenesis of yeast dicarboxylate carrier: the carrier signature facilitates translocation across the mitochondrial outer membrane.

  Journal of cell science 20071201

• Monoamine oxidase-B inhibition in the treatment of Parkinson's disease.

  Pharmacotherapy 20071201

• Micromonospora lupini sp. nov. and Micromonospora saelicesensis sp. nov., isolated from root nodules of Lupinus angustifolius.

  International journal of systematic and evolutionary microbiology 20071201

• Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with peak bone mass in non-sedentary men: results from the Odense androgen study.

  Calcified tissue international 20071201

• [Metabonomic study of blood plasma in the assessment of liver graft function].

  Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20071201

• Identification of biomolecular conformations from incomplete torsion angle observations by hidden Markov models.

  Journal of computational chemistry 20071130

• The mitotic regulator Survivin binds as a monomer to its functional interactor Borealin.

  The Journal of biological chemistry 20071130

• Clostridium difficile glucosyltransferase toxin B-essential amino acids for substrate binding.

  The Journal of biological chemistry 20071130

• RNAi of 14-3-3eta protein increases intracellular stability of tyrosine hydroxylase.

  Biochemical and biophysical research communications 20071123

• The natural product avrainvillamide binds to the oncoprotein nucleophosmin.

  Journal of the American Chemical Society 20071121

• Elongation factor Tu mutants expand amino acid tolerance of protein biosynthesis system.

  Journal of the American Chemical Society 20071121

• Two SCA (stigma/style cysteine-rich adhesin) isoforms show structural differences that correlate with their levels of in vitro pollen tube adhesion activity.

  The Journal of biological chemistry 20071116

• Specific sites in the cytoplasmic N terminus modulate conformational transitions of the Na,K-ATPase.

  The Journal of biological chemistry 20071116

• Proton transport behavior through the influenza A M2 channel: insights from molecular simulation.

  Biophysical journal 20071115

• Human wild-type alanine:glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications.

  The Biochemical journal 20071115

• Exact low-force kinetics from high-force single-molecule unfolding events.

  Biophysical journal 20071115

• A multigram chemical synthesis of the gamma-secretase inhibitor LY411575 and its diastereoisomers.

  Bioorganic & medicinal chemistry letters 20071115

• Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs.

  Journal of medicinal chemistry 20071115

• Mapping of a region of Ebola virus VP40 that is important in the production of virus-like particles.

  The Journal of infectious diseases 20071115

• Probing molecular interactions within class II MHC Aq/glycopeptide/T-cell receptor complexes associated with collagen-induced arthritis.

  Journal of medicinal chemistry 20071115

• Nanoporous magnets of chiral and racemic [{Mn(HL)}2Mn{Mo(CN)7}2] with switchable ordering temperatures (TC = 85 K <--> 106 K) driven by H2O sorption (L = N,N-dimethylalaninol).

  Journal of the American Chemical Society 20071114

• The pestivirus glycoprotein Erns is anchored in plane in the membrane via an amphipathic helix.

  The Journal of biological chemistry 20071109

• AdoMet-dependent methyl-transfer: Glu119 is essential for DNA C5-cytosine methyltransferase M.HhaI.

  Journal of molecular biology 20071109

• Estimating kinetic rates from accelerated molecular dynamics simulations: alanine dipeptide in explicit solvent as a case study.

  The Journal of chemical physics 20071107

• Stochastic dipolar recoupling in nuclear magnetic resonance of solids.

  Physical review letters 20071102

• Uranyl binary and ternary chelates of tenoxicam Synthesis, spectroscopic and thermal characterization of ternary chelates of tenoxicam and alanine with transition metals.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20071101

• An analysis of peroxisome proliferator-activated receptor gamma (PPAR-gamma 2) Pro12Ala polymorphism distribution and prevalence of type 2 diabetes mellitus (T2DM) in world populations in relation to dietary habits.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20071101

• Analyses of GDF9 mutation in 100 Chinese women with premature ovarian failure.

  Fertility and sterility 20071101

• Freezing and anoxia tolerance of slugs: a metabolic perspective.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20071101

• Effect of the Ala12 allele in the PPARgamma-2 gene on the relationship between birth weight and body composition in adolescents: the AVENA study.

  Pediatric research 20071101

• 4-arylcyclohexylalanine analogs as potent, selective, and orally active inhibitors of dipeptidyl peptidase IV.

  Bioorganic & medicinal chemistry letters 20071101

• Novel orally active, dibenzazepinone-based gamma-secretase inhibitors.

  Bioorganic & medicinal chemistry letters 20071101

• Absence of KCNQ1-dependent K+ fluxes in proximal tubular cells of frog kidney.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20071101

• Production of L -alanine by metabolically engineered Escherichia coli.

  Applied microbiology and biotechnology 20071101

• Testing beta-helix terminal coils stability by targeted substitutions with non-proteogenic amino acids: a molecular dynamics study.

  Journal of structural biology 20071101

• Action of celecoxib on hepatic metabolic changes induced by the Walker-256 tumour in rats.

  Basic & clinical pharmacology & toxicology 20071101

• A translocation signal for delivery of oomycete effector proteins into host plant cells.

  Nature 20071101

• Identification of four major hornet silk genes with a complex of alanine-rich and serine-rich sequences in Vespa simillima xanthoptera Cameron.

  Bioscience, biotechnology, and biochemistry 20071101

• Conformational manifold of alpha-aminoisobutyric acid (Aib) containing alanine-based tripeptides in aqueous solution explored by vibrational spectroscopy, electronic circular dichroism spectroscopy, and molecular dynamics simulations.

  Journal of the American Chemical Society 20071031

• Differential colchicine-binding across eukaryotic families: the role of highly conserved Pro268beta and Ala248beta residues in animal tubulin.

  FEBS letters 20071030

• A highly stereocontrolled total synthesis of dysiherbaine.

  Chemical communications (Cambridge, England) 20071028

• Near-edge x-ray absorption and natural circular dichroism spectra of L-alanine: a theoretical study based on the complex polarization propagator approach.

  The Journal of chemical physics 20071028

• [Side effects of gastric muco-protective agents].

  Nihon rinsho. Japanese journal of clinical medicine 20071028

• Bis-methionine ligation to heme iron in the streptococcal cell surface protein Shp facilitates rapid hemin transfer to HtsA of the HtsABC transporter.

  The Journal of biological chemistry 20071026

• Tetraspanin CD151 promotes cell migration by regulating integrin trafficking.

  The Journal of biological chemistry 20071026

• Molecular mechanism of oxidative stress perception by the Orp1 protein.

  The Journal of biological chemistry 20071026

• Factors affecting guanine nucleotide binding to rat AMPA receptors.

  Brain research 20071026

• A multinuclear copper(I) cluster forms the dimerization interface in copper-loaded human copper chaperone for superoxide dismutase.

  Biochemistry 20071023

• Role of the N-terminal helix in the metal ion-induced activation of the diphtheria toxin repressor DtxR.

  Biochemistry 20071023

• Kinetic and stereochemical analysis of YwhB, a 4-oxalocrotonate tautomerase homologue in Bacillus subtilis: mechanistic implications for the YwhB- and 4-oxalocrotonate tautomerase-catalyzed reactions.

  Biochemistry 20071023

• Conformation-specific infrared and ultraviolet spectroscopy of tyrosine-based protonated dipeptides.

  The Journal of chemical physics 20071021

• Structure of the antiviral assembly inhibitor CAP-1 complex with the HIV-1 CA protein.

  Journal of molecular biology 20071019

• Conformation, dynamics, and insertion of a noncysteine-containing protegrin-1 analogue in lipid membranes from solid-state NMR spectroscopy.

  Chembiochem : a European journal of chemical biology 20071015

• Metabolic impact of overexpression of liver glycogen synthase with serine-to-alanine substitutions in rat primary hepatocytes.

  Archives of biochemistry and biophysics 20071015

• Stereoselective syntheses of 4-oxa diaminopimelic acid and its protected derivatives via aziridine ring opening.

  Organic letters 20071011

• In vitro effect of PPAR-gamma2 Pro12Ala polymorphism on the deposition of Alzheimer's amyloid-beta peptides.

  Brain research 20071010

• Positional assignment of differentially substituted bisaminoacylated pdCpAs.

  Organic & biomolecular chemistry 20071007

• Solid-phase synthesis and insights into structure-activity relationships of safinamide analogues as potent and selective inhibitors of type B monoamine oxidase.

  Journal of medicinal chemistry 20071004

• Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha-synuclein: Implication for alpha-synucleinopathies.

  FEBS letters 20071002

• Indirect resolution of enantiomers of penicillamine by TLC and HPLC using Marfey's reagent and its variants.

  Biomedical chromatography : BMC 20071001

• Characterization of new L,D-endopeptidase gene product CwlK (previous YcdD) that hydrolyzes peptidoglycan in Bacillus subtilis.

  Molecular genetics and genomics : MGG 20071001

• Pharmacokinetics, metabolism, and excretion of the intestinal peptide transporter 1 (SLC15A1)-targeted prodrug (1S,2S,5R,6S)-2-[(2'S)-(2-amino)propionyl]aminobicyclo[3.1.0.]hexen-2,6-dicarboxylic acid (LY544344) in rats and dogs: assessment of first-pass bioactivation and dose linearity.

  Drug metabolism and disposition: the biological fate of chemicals 20071001

• Flexibility of the hepatic zonation of carbon and nitrogen fluxes linked to lactate and pyruvate transformations in the presence of ammonia.

  American journal of physiology. Gastrointestinal and liver physiology 20071001

• A Thr94Ala mutation in human liver fatty acid-binding protein contributes to reduced hepatic glycogenolysis and blunted elevation of plasma glucose levels in lipid-exposed subjects.

  American journal of physiology. Endocrinology and metabolism 20071001

• Determination of NMR interaction parameters from double rotation NMR.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20071001

• Efficient cross polarization with simultaneous adiabatic frequency sweep on the source and target channels.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20071001

• Clinical application of C-reactive protein across the spectrum of acute coronary syndromes.

  Clinical chemistry 20071001

• Loop propensity of the sequence YKGQP from staphylococcal nuclease: implications for the folding of nuclease.

  Journal of peptide science : an official publication of the European Peptide Society 20071001

• Ninjurin 1 asp110ala single nucleotide polymorphism is associated with protection in leprosy nerve damage.

  Journal of neuroimmunology 20071001

• Molecular modeling of conformational properties of oligodepsipeptides.

  Biomacromolecules 20071001

• Antithrombin Cambridge II (A384S): prevalence in patients of the Paris Thrombosis Study (PATHROS).

  Blood 20071001

• Structural studies on Vibrio cholerae ToxR periplasmic and cytoplasmic domains.

  Biochimica et biophysica acta 20071001

• Generation of quinoneimine intermediates in the bioactivation of 3-(N-phenylamino)alanine (PAA) by human liver microsomes: a potential link between eosinophilia-myalgia syndrome and toxic oil syndrome.

  Chemical research in toxicology 20071001

• Least-squares chemical shift separation for (13)C metabolic imaging.

  Journal of magnetic resonance imaging : JMRI 20071001

• Managlinat dialanetil, a fructose-1,6-bisphosphatase inhibitor for the treatment of type 2 diabetes.

  Current opinion in investigational drugs (London, England : 2000) 20071001

• Pro-inflammatory cytokines increase glucose, alanine and triacylglycerol utilization but inhibit insulin secretion in a clonal pancreatic beta-cell line.

  The Journal of endocrinology 20071001

• Asp125 and Thr130 in transmembrane domain 3 are major sites of alpha1b-adrenergic receptor antagonist binding.

  Biological & pharmaceutical bulletin 20071001

• Implementation of a k/k(0) method to identify long-range structure in transition states during conformational folding/unfolding of proteins.

  Structure (London, England : 1993) 20071001

• Fibrinogen Leipzig II (gamma351Gly-->Ser and gamma82Ala-->Gly): hypodysfibrinogenaemia due to two independent amino acid substitutions within the same polypeptide chain.

  Thrombosis and haemostasis 20071001

• Prophylactic effect of rebamipide against the irritative and healing impairment actions of alendronate in rat stomachs.

  Inflammopharmacology 20071001

• Synthesis and anti-HIV evaluation of hybrid-type prodrugs conjugating HIV integrase inhibitors with d4t by self-cleavable spacers containing an amino acid residue.

  Journal of enzyme inhibition and medicinal chemistry 20071001

• Manganese superoxide dismutase (MnSOD: Ala-9Val) gene polymorphism may not be associated with schizophrenia and tardive dyskinesia.

  Psychiatry research 20070930

• Alteration of the quaternary structure of human UDP-glucose dehydrogenase by a double mutation.

  Journal of biochemistry and molecular biology 20070930

• Hantzsch-type three-component approach to a new family of carbon-linked glycosyl amino acids. Synthesis of C-glycosylmethyl pyridylalanines.

  The Journal of organic chemistry 20070928

• Interactions of L-alanine with alumina as studied by vibrational spectroscopy.

  Langmuir : the ACS journal of surfaces and colloids 20070925

• A C-terminal dimerization motif is required for focal adhesion targeting of Talin1 and the interaction of the Talin1 I/LWEQ module with F-actin.

  Biochemistry 20070925

• The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR.

  The Journal of biological chemistry 20070921

• Entrapped energy in chiral solutions: quantification and information capacity.

  The journal of physical chemistry. B 20070920

• Molecular recognition and screening using a 15N group selective STD NMR method.

  Journal of the American Chemical Society 20070919

• The TGFBI A546D mutation causes an atypical type of lattice corneal dystrophy.

  Molecular vision 20070917

• The conserved glycine/alanine residue of the active-site loop containing the putative acetylCoA-binding motif is essential for the overall structural integrity of Mesorhizobium loti arylamine N-acetyltransferase 1.

  Biochemical and biophysical research communications 20070914

• Conversion of nocathiacin I to nocathiacin acid by a mild and selective cleavage of dehydroalanine.

  The Journal of organic chemistry 20070914

• Binding of TPX2 to Aurora A alters substrate and inhibitor interactions.

  Biochemistry 20070911

• A matrix isolation study on Ac-Gly-NHMe and Ac-l-Ala-NHMe, the simplest chiral and achiral building blocks of peptides and proteins.

  Physical chemistry chemical physics : PCCP 20070907

• Intrinsic primary and secondary hydrogen kinetic isotope effects for alanine racemase from global analysis of progress curves.

  Journal of the American Chemical Society 20070905

• Enantioselective screen-printed amperometric biosensor for the determination of D-amino acids.

  Bioelectrochemistry (Amsterdam, Netherlands) 20070901

• Elimination of racemic and enantioenriched metalaxyl based fungicides under tropical conditions in the field.

  Chemosphere 20070901

• Major Cdk5-dependent phosphorylation sites of amphiphysin 1 are implicated in the regulation of the membrane binding and endocytosis.

  Journal of neurochemistry 20070901

• D-glucose stimulation of L-arginine transport and nitric oxide synthesis results from activation of mitogen-activated protein kinases p42/44 and Smad2 requiring functional type II TGF-beta receptors in human umbilical vein endothelium.

  Journal of cellular physiology 20070901

• Solution conformation of the His-47 to Ala-47 mutant of Pseudomonas stutzeri ZoBell ferrocytochrome c-551.

  Biophysical journal 20070901

• Alanine metabolism, transport, and cycling in the brain.

  Journal of neurochemistry 20070901

• Characterization of transport systems for cysteine, lysine, alanine, and leucine in wool follicles of sheep.

  Journal of animal science 20070901

• Antifreeze proteins at the ice/water interface: three calculated discriminating properties for orientation of type I proteins.

  Biophysical journal 20070901

• Molecular characterization of cold adaptation based on ortholog protein sequences from Vibrionaceae species.

  Extremophiles : life under extreme conditions 20070901

• Alanine production in an H+-ATPase- and lactate dehydrogenase-defective mutant of Escherichia coli expressing alanine dehydrogenase.

  Applied microbiology and biotechnology 20070901

• The lack of effect of specific overexpression of IGF-1 in the central nervous system or skeletal muscle on pathophysiology in the G93A SOD-1 mouse model of ALS.

  Experimental neurology 20070901

• Optimization of solid-phase synthesis of difficult peptide sequences via comparison between different improved approaches.

  Amino acids 20070901

• Activation of the Nrf2-ARE pathway in muscle and spinal cord during ALS-like pathology in mice expressing mutant SOD1.

  Experimental neurology 20070901

• Bioavailability of the amino acid-attached prodrug as a new anti-HIV agent in rats.

  Journal of veterinary science 20070901

• Understanding the chemistry of the development of latent fingerprints by superglue fuming.

  Journal of forensic sciences 20070901

• [Soluble CD40 ligand: a potential marker of cardiovascular risk].

  Revista clinica espanola 20070901

• Combinations of two amino acids (Ala40 and Phe75 or Ser40 and Tyr75) in the coat protein of apple chlorotic leaf spot virus are crucial for infectivity.

  The Journal of general virology 20070901

• Thermal stability effects of removing the type-2 copper ligand His306 at the interface of nitrite reductase subunits.

  European biophysics journal : EBJ 20070901

• Classification of 'Sarraceniospora aurea' Furihata et al. 1989 as Actinocorallia aurea sp. nov.

  International journal of systematic and evolutionary microbiology 20070901

• Crystallization and preliminary crystallographic analysis of D-alanine-D-alanine ligase from Streptococcus mutans.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20070901

• Association between migraine and the G1246A polymorphism in the hypocretin receptor 2 gene.

  Headache 20070901

• Trierixin, a novel Inhibitor of ER stress-induced XBP1 activation from Streptomyces sp. 1. Taxonomy, fermentation, isolation and biological activities.

  The Journal of antibiotics 20070901

• Antiaggregant effects of biogenic chloramines.

  Bulletin of experimental biology and medicine 20070901

• Effects of mutational (Lys to Ala) surface charge changes on the redox properties of electrode-immobilized cytochrome c.

  The journal of physical chemistry. B 20070830

• On the oligomeric state of DJ-1 protein and its mutants associated with Parkinson Disease. A combined computational and in vitro study.

  The Journal of biological chemistry 20070824

• Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction.

  The Journal of biological chemistry 20070824

• Role of non-phosphorylated activation loop residues in determining ERK2 dephosphorylation, activity, and subcellular localization.

  The Journal of biological chemistry 20070824

• Carboxy-terminus recruitment induced by substrate binding in eukaryotic fructose bis-phosphate aldolases.

  Biochemistry 20070821

• Metal-mediated peptide assembly: use of metal coordination to change the oligomerization state of an alpha-helical coiled-coil.

  Inorganic chemistry 20070820

• H bonding at the helix-bundle crossing controls gating in Kir potassium channels.

  Neuron 20070816

• Spectrophotometric determination of peptide transport with chromogenic peptide mimetics.

  Analytical biochemistry 20070815

• Rate-limiting steps and role of active site Lys443 in the mechanism of carbapenam synthetase.

  Biochemistry 20070814

• Annealed importance sampling of peptides.

  The Journal of chemical physics 20070814

• Functional links between the fusion peptide-proximal polar segment and membrane-proximal region of human immunodeficiency virus gp41 in distinct phases of membrane fusion.

  The Journal of biological chemistry 20070810

• Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis. Crystal structures of the enzyme alpha-aminoacrylate intermediate and an enzyme-inhibitor complex.

  The Journal of biological chemistry 20070810

• Rigid conformation of an immunoglobulin domain tandem repeat in the A-band of the elastic muscle protein titin.

  Journal of molecular biology 20070810

• Domain organization and polarity of tail needle GP26 in the portal vertex structure of bacteriophage P22.

  Journal of molecular biology 20070810

• WNK4 phosphorylates ser(206) of claudin-7 and promotes paracellular Cl(-) permeability.

  FEBS letters 20070807

• Dissecting differential binding of fructose and phosphate as leaving group/nucleophile of glucosyl transfer catalyzed by sucrose phosphorylase.

  FEBS letters 20070807

• Complexation of Al(III) by aromatic amino acids in the gas phase.

  Inorganic chemistry 20070806

• Molecular insight into the interaction between IFABP and PA by using MM-PBSA and alanine scanning methods.

  The journal of physical chemistry. B 20070802

• High-field 1H MAS and 15N CP-MAS NMR studies of alanine tripeptides and oligomers: distinction of antiparallel and parallel beta-sheet structures and two crystallographically independent molecules.

  The journal of physical chemistry. B 20070802

• Changes in plasma metabolites and muscle glycogen are correlated to bovine spongiform encephalopathy in infected dairy cattle.

  Research in veterinary science 20070801

• Effects of adenosine monophosphate-activated kinase activators on bovine oocyte nuclear maturation in vitro.

  Molecular reproduction and development 20070801

• FABP2 Ala54Thr polymorphism and diabetes in Chilean elders.

  Diabetes research and clinical practice 20070801

• The metabolic changes caused by dexamethasone in the adjuvant-induced arthritic rat.

  Molecular and cellular biochemistry 20070801

• DFT studies using supercells and projector-augmented waves for structure, energetics, and dynamics of glycine, alanine, and cysteine.

  Journal of computational chemistry 20070801

• Preventive effects of rebamipide on NSAID-induced gastric mucosal injury and reduction of gastric mucosal blood flow in healthy volunteers.

  Digestive diseases and sciences 20070801

• A study of local effect and global effect on the microthermal bio-flows by molecular dynamics.

  International journal of biological macromolecules 20070801

• Effect of an Asp80Ala substitution on the binding of dUTP and dUMP to Trypanosoma cruzi dUTPase.

  Biochimie 20070801

• Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits.

  The Journal of pharmacology and experimental therapeutics 20070801

• An N-terminal nucleotide-binding site in VDAC1: involvement in regulating mitochondrial function.

  Journal of cellular physiology 20070801

• Differential inhibition of CYP17A1 and CYP21A2 activities by the P450 oxidoreductase mutant A287P.

  Molecular endocrinology (Baltimore, Md.) 20070801

• Determination of chemical shift anisotropies of unresolved carbonyl sites by C-alpha detection under magic-angle spinning.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20070801

• Solvent-mediated proton transfer in catalysis by carbonic anhydrase.

  Accounts of chemical research 20070801

• Empirical isotropic chemical shift surfaces.

  Journal of biomolecular NMR 20070801

• A new method for the extracellular production of recombinant thermolysin by co-expressing the mature sequence and pro-sequence in Escherichia coli.

  Protein engineering, design & selection : PEDS 20070801

• Familial haemophagocytic lymphohistiocytosis in patients who are heterozygous for the A91V perforin variation is often associated with other genetic defects.

  International journal of immunogenetics 20070801

• Accurate charge density of the tripeptide Ala-Pro-Ala with the maximum entropy method (MEM): influence of data resolution.

  Acta crystallographica. Section B, Structural science 20070801

• Functional variant of manganese superoxide dismutase (SOD2 V16A) polymorphism is associated with prostate cancer risk in the prostate, lung, colorectal, and ovarian cancer study.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070801

• Optimization of fast spiral chemical shift imaging using least squares reconstruction: application for hyperpolarized (13)C metabolic imaging.

  Magnetic resonance in medicine 20070801

• Structural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domain.

  Protein science : a publication of the Protein Society 20070801

• Structure-function studies of peptides for cell adhesion inhibition: identification of key residues by alanine mutation and peptide-truncation approach.

  Peptides 20070801

• Effects of Ala substitution for conserved Cys residues in mouse ileal and hepatic Na+-dependent bile acid transporters.

  Bioscience, biotechnology, and biochemistry 20070801

• Rebamipide, a gastro-protective and anti-inflammatory drug, promotes gastric ulcer healing following eradication therapy for Helicobacter pylori in a Japanese population: a randomized, double-blind, placebo-controlled trial.

  Journal of gastroenterology 20070801

• Determination of pesticide residues in soil by modified matrix solid-phase dispersion and gas chromatography.

  Annali di chimica 20070801

• Rapid single-step methods for detection of two immune defence gene polymorphisms: the myeloperoxidase (MPO) G-129A and the Fc gamma receptor 2A (FCGR2A) H/R131.

  Journal of immunological methods 20070731

• Single A326G mutation converts human CYP24A1 from 25-OH-D3-24-hydroxylase into -23-hydroxylase, generating 1alpha,25-(OH)2D3-26,23-lactone.

  Proceedings of the National Academy of Sciences of the United States of America 20070731

• Expansion of the first PolyA tract of ARX causes infantile spasms and status dystonicus.

  Neurology 20070731

• Interaction of thrombin with PAR1 and PAR4 at the thrombin cleavage site.

  Biochemistry 20070724

• Measurement of solvation responses at multiple sites in a globular protein.

  The journal of physical chemistry. B 20070719

• Alanine scan of [L-Dap(2)]ramoplanin A2 aglycon: assessment of the importance of each residue.

  Journal of the American Chemical Society 20070718

• Nonconserved residues Ala287 and Ser290 of the Cryptosporidium hominis thymidylate synthase domain facilitate its rapid rate of catalysis.

  Biochemistry 20070717

• Discovery of (S)-2-((S)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S,Z)-3-methyl-4-oxo-4,5-dihydro-3H-benzo[d][1,2]diazepin-5-yl)propanamide (BMS-433796): a gamma-secretase inhibitor with Abeta lowering activity in a transgenic mouse model of Alzheimer's disease.

  Bioorganic & medicinal chemistry letters 20070715

• Discovery and validation of biomarkers that respond to treatment with brivanib alaninate, a small-molecule VEGFR-2/FGFR-1 antagonist.

  Cancer research 20070715

• Chain initiation in the leinamycin-producing hybrid nonribosomal peptide/polyketide synthetase from Streptomyces atroolivaceus S-140. Discrete, monofunctional adenylation enzyme and peptidyl carrier protein that directly load D-alanine.

  The Journal of biological chemistry 20070713

• Contribution of the putative inner-pore region to the gating of the transient receptor potential vanilloid subtype 1 channel (TRPV1).

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070711

• Numerical integration techniques for curved-element discretizations of molecule-solvent interfaces.

  The Journal of chemical physics 20070707

• On use of the Amber potential with the Langevin dipole method.

  The journal of physical chemistry. B 20070705

• The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo.

  The Journal of clinical investigation 20070702

• Blood amino acids concentration during insulin induced hypoglycemia in rats: the role of alanine and glutamine in glucose recovery.

  Amino acids 20070701

• Polymorphisms of CD3epsilon in cynomolgus and rhesus monkeys and their relevance to anti-CD3 antibodies and immunotoxins.

  Immunology and cell biology 20070701

• Alanine peak in central neurocytomas on proton MR spectroscopy.

  Neuroradiology 20070701

• Underexpression of the Na+-dependent neutral amino acid transporter ASCT2 in the spontaneously hypertensive rat kidney.

  American journal of physiology. Regulatory, integrative and comparative physiology 20070701

• Agonist-dependent consequences of proline to alanine substitution in the transmembrane helices of the calcitonin receptor.

  British journal of pharmacology 20070701

• Synthesis of bisaminoacylated pdCpAs and tandemly activated transfer RNAs.

  Bioorganic & medicinal chemistry 20070701

• Selective oxidative stress in cell nuclei by nuclear-targeted D-amino acid oxidase.

  Antioxidants & redox signaling 20070701

• Direct correlation between ischemic injury and extracellular glycine concentration in mice with genetically altered activities of the glycine cleavage multienzyme system.

  Stroke 20070701

• The role of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma in diabetes risk.

  Current opinion in clinical nutrition and metabolic care 20070701

• Polymorphism in the manganese superoxide dismutase gene.

  Free radical research 20070701

• Identification of a novel lipid raft-targeting motif in Src homology 2-containing phosphatase 1.

  Journal of immunology (Baltimore, Md. : 1950) 20070701

• Hair is the news.

  Molecular bioSystems 20070701

• Development of polymeric gene delivery carriers: PEGylated copolymers of L-lysine and L-phenylalanine.

  Journal of drug targeting 20070701

• Rubritalea squalenifaciens sp. nov., a squalene-producing marine bacterium belonging to subdivision 1 of the phylum 'Verrucomicrobia'.

  International journal of systematic and evolutionary microbiology 20070701

• Mutation of a key residue in the type II secretion system ATPase uncouples ATP hydrolysis from protein translocation.

  Molecular microbiology 20070701

• Up-to-date information on gastric mucosal lesions from long-term NSAID therapy in orthopedic outpatients: a study using logistic regression analysis.

  Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20070701

• Safinamide for the treatment of Parkinson's disease, epilepsy and restless legs syndrome.

  Current opinion in investigational drugs (London, England : 2000) 20070701

• Calculation of the distribution of eigenvalues and eigenvectors in Markovian state models for molecular dynamics.

  The Journal of chemical physics 20070628

• Dihedral angle principal component analysis of molecular dynamics simulations.

  The Journal of chemical physics 20070628

• Rational design, structural and thermodynamic characterization of a hyperstable variant of the villin headpiece helical subdomain.

  Biochemistry 20070626

• Calcicludine binding to the outer pore of L-type calcium channels is allosterically coupled to dihydropyridine binding.

  Biochemistry 20070626

• Probing electrostatic interactions along the reaction pathway of a glycoside hydrolase: histidine characterization by NMR spectroscopy.

  Biochemistry 20070626

• Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4.

  The Journal of biological chemistry 20070622

• Mode of membrane interaction and fusogenic properties of a de novo transmembrane model peptide depend on the length of the hydrophobic core.

  The Journal of biological chemistry 20070622

• Conformation dependence of the CalphaDalpha stretch mode in peptides. 1. Isolated alanine peptide structures.

  The journal of physical chemistry. A 20070621

• C-terminal modification is required for GABARAP-mediated GABA(A) receptor trafficking.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070620

• Thermodynamic investigation of the role of contact residues of beta-lactamase-inhibitory protein for binding to TEM-1 beta-lactamase.

  The Journal of biological chemistry 20070615

• Structural determinants for ligand-receptor conformational selection in a peptide G protein-coupled receptor.

  The Journal of biological chemistry 20070615

• Metabolomic alterations in elicitor treated Silybum marianum suspension cultures monitored by nuclear magnetic resonance spectroscopy.

  Journal of biotechnology 20070615

• A novel mutation in human ether-a-go-go-related gene, alanine to proline at position 490, found in a large family with autosomal dominant long QT syndrome.

  The American journal of cardiology 20070615

• Anharmonic effects in IR, Raman, and Raman optical activity spectra of alanine and proline zwitterions.

  The Journal of chemical physics 20070614

• Stereoselective iodocyclization of (S)-allylalanine derivatives: gamma-lactone vs cyclic carbamate formation.

  Organic letters 20070607

• High-resolution, high-sensitivity NMR of nanolitre anisotropic samples by coil spinning.

  Nature 20070607

• Beta-styryl- and beta-aryl-beta-alanine products of phenylalanine aminomutase catalysis.

  Journal of the American Chemical Society 20070606

• MECP2 coding sequence and 3'UTR variation in 172 unrelated autistic patients.

  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20070605

• Mutagenesis of lysine 62, asparagine 64, and conserved region 1 reduces the activity of human ecto-ATPase (NTPDase 2).

  Biochemistry 20070605

• Effects of a mutation in the TM2-TM3 linker region of the glycine receptor alpha1 subunit on gating and allosteric modulation.

  Brain research 20070604

• Cleavage after residue Ala352 in the C-terminal extension is an early step in the maturation of the D1 subunit of Photosystem II in Synechocystis PCC 6803.

  Biochimica et biophysica acta 20070601

• Regulator of G-protein signalling 3 redirects prototypical Gi-coupled receptors from Rac1 to RhoA activation.

  Cellular signalling 20070601

• The role of Tyr605 and Ala607 of thimet oligopeptidase and Tyr606 and Gly608 of neurolysin in substrate hydrolysis and inhibitor binding.

  The Biochemical journal 20070601

• Inhibition of melanoma cell motility by the snake venom disintegrin eristostatin.

  Toxicon : official journal of the International Society on Toxinology 20070601

• Amino acid and codon use: in two influenza viruses and three hosts.

  Medecine et maladies infectieuses 20070601

• Mutations of Cys-17 and Ala-271 in the human histamine H2 receptor determine the species selectivity of guanidine-type agonists and increase constitutive activity.

  The Journal of pharmacology and experimental therapeutics 20070601

• Local inhibitory reflexes excited by mucosal application of nutrient amino acids in guinea pig jejunum.

  American journal of physiology. Gastrointestinal and liver physiology 20070601

• Measurement of liver collagen synthesis by heavy water labeling: effects of profibrotic toxicants and antifibrotic interventions.

  American journal of physiology. Gastrointestinal and liver physiology 20070601

• Leisure-time physical activity is associated with the metabolic syndrome in type 1 diabetes: effect of the PPARgamma Pro12Ala polymorphism: the FinnDiane Study.

  Diabetes care 20070601

• Alanine to serine polymorphism at position 986 of the calcium-sensing receptor associated with coronary heart disease, myocardial infarction, all-cause, and cardiovascular mortality.

  The Journal of clinical endocrinology and metabolism 20070601

• Comparison between computational alanine scanning and per-residue binding free energy decomposition for protein-protein association using MM-GBSA: application to the TCR-p-MHC complex.

  Proteins 20070601

• Type 2 deiodinase Thr92Ala polymorphism is not associated with arterial hypertension in type 2 diabetes mellitus patients.

  Hypertension (Dallas, Tex. : 1979) 20070601

• Study on the isomerism in meso-amavadin and an amavadin analogue.

  Journal of inorganic biochemistry 20070601

• The Pro12Ala polymorphism in PPARG2 increases the effectiveness of primary prevention of cardiovascular disease by a lifestyle intervention.

  Diabetologia 20070601

• Introducing genetically encoded aldehydes into proteins.

  Nature chemical biology 20070601

• Complementation of an E. coli cysteine auxotrophic mutant for the structural modification study of 3'(2'),5'-bisphosphate nucleotidase.

  Biotechnology letters 20070601

• Structural modelling and mutation analysis of a nociceptin receptor and its ligand complexes.

  Journal of biochemistry 20070601

• Efficacy of anticoagulants and platelet inhibitors in cancer-induced thrombosis.

  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20070601

• Effect of selected Ser/Ala and Xaa/Pro mutations on the stability and catalytic properties of a cold adapted subtilisin-like serine proteinase.

  Biochimica et biophysica acta 20070601

• Exploring and designing protein function with restricted diversity.

  Current opinion in chemical biology 20070601

• Intragenic Cis and Trans modification of genetic susceptibility in DYT1 torsion dystonia.

  American journal of human genetics 20070601

• Mutation of cysteine residue 455 to alanine in human topoisomerase IIalpha confers hypersensitivity to quinones: enhancing DNA scission by closing the N-terminal protein gate.

  Chemical research in toxicology 20070601

• Effect of dipeptide of glutamine and alanine on severe traumatic brain injury.

  Chinese journal of traumatology = Zhonghua chuang shang za zhi 20070601

• Effect of rectal administration of rebamipide on dextran sulfate sodium-induced colitis: role of hepatocyte growth factor.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20070601

• Purine nucleoside phosphorylase deficiency in a patient with spastic paraplegia and recurrent infections.

  Journal of child neurology 20070601

• Novel mutations in exon 6 of the GFAP gene affect a highly conserved if motif in the rod domain 2B and are associated with early onset infantile Alexander disease.

  Neuropediatrics 20070601

• Germination of Bacillus cereus spores adhered to stainless steel.

  International journal of food microbiology 20070530

• Development of an electrolytic system for non-Kolbe electrolysis based on the acid-base reaction between carboxylic acids as a substrate and solid-supported bases.

  Journal of the American Chemical Society 20070530

• Infrared spectroscopy and structure of photochemically protonated biomolecules in the gas phase: a noradrenaline analogue, lysine and alanyl alanine.

  Physical chemistry chemical physics : PCCP 20070528

• On the helix-coil transition in alanine based polypeptides in gas phase.

  The Journal of chemical physics 20070528

• Retention of pesticides in soil columns modified in situ and ex situ with a cationic surfactant.

  The Science of the total environment 20070525

• Alanine scanning and Fe-BABE probing of the bacteriophage ø29 prohead RNA-connector interaction.

  Journal of molecular biology 20070525

• Electron transfer to protonated beta-alanine N-methylamide in the gas phase: an experimental and computational study of dissociation energetics and mechanisms.

  The journal of physical chemistry. A 20070524

• Electronic excitations of glycine, alanine, and cysteine conformers from first-principles calculations.

  The journal of physical chemistry. A 20070524

• Laser photoexcitation of NAD(P)H induces reduction of P450 BM3 heme domain on the microsecond time scale.

  Journal of the American Chemical Society 20070523

• Bioflavonoids as poisons of human topoisomerase II alpha and II beta.

  Biochemistry 20070522

• Histidine 282 in 5-aminolevulinate synthase affects substrate binding and catalysis.

  Biochemistry 20070522

• Synthesis of libraries of thiazole, oxazole and imidazole-based cyclic peptides from azole-based amino acids. A new synthetic approach to bistratamides and didmolamides.

  Organic & biomolecular chemistry 20070521

• Structural isotopic effects in the smallest chiral amino acid: observation of a structural phase transition in fully deuterated alanine.

  The journal of physical chemistry. B 20070517

• Time-domain calculations of the infrared and polarized Raman spectra of tetraalanine in aqueous solution.

  The journal of physical chemistry. B 20070517

• Synthesis and characterization of constrained peptidomimetic dipeptidyl peptidase IV inhibitors: amino-lactam boroalanines.

  Journal of medicinal chemistry 20070517

• Spectroscopic and computational evaluation of the structure of the high-spin Fe(IV)-oxo intermediates in taurine: alpha-ketoglutarate dioxygenase from Escherichia coli and its His99Ala ligand variant.

  Journal of the American Chemical Society 20070516

• Antithrombin Cambridge II (A384S): an underestimated genetic risk factor for venous thrombosis.

  Blood 20070515

• 4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV.

  Bioorganic & medicinal chemistry letters 20070515

• Potential anti-inflammatory actions of the elmiric (lipoamino) acids.

  Bioorganic & medicinal chemistry 20070515

• Metabolic profiling of serum from gadolinium chloride-treated rats by 1H NMR spectroscopy.

  Analytical biochemistry 20070515

• Magnetic resonance spectroscopy reveals an impaired brain metabolic profile in mice resistant to cerebral malaria infected with Plasmodium berghei ANKA.

  The Journal of biological chemistry 20070511

• Aberrant amino acid transport in fibroblasts from children with autism.

  Neuroscience letters 20070511

• A highly stereoselective synthesis of (-)-(ent)-julifloridine from the cyclization of an alanine-derived chloroamine with an acetylenic sulfone.

  The Journal of organic chemistry 20070511

• A unified kinetic mechanism applicable to multiple DNA polymerases.

  Biochemistry 20070508

• Periodic orbits in biological molecules: phase space structures and selectivity in alanine dipeptide.

  The Journal of chemical physics 20070507

• Stereoselective degradation of fungicide benalaxyl in soils and cucumber plants.

  Chirality 20070505

• Behavioral phenotypes of Disc1 missense mutations in mice.

  Neuron 20070503

• Tunable-alignment chiral system based on gelatin for NMR spectroscopy.

  Journal of the American Chemical Society 20070502

• A large German kindred with cold-aggravated myotonia and a heterozygous A1481D mutation in the SCN4A gene.

  Muscle & nerve 20070501

• Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps.

  Cellular microbiology 20070501

• Determination of protein replacement rates by deuterated water: validation of underlying assumptions.

  American journal of physiology. Endocrinology and metabolism 20070501

• Pro12Ala polymorphism of the PPARgamma2 locus modulates the relationship between energy intake and body weight in type 2 diabetic patients.

  Diabetes care 20070501

• Solute-inhibitor interactions in the plasmodial surface anion channel reveal complexities in the transport process.

  Molecular pharmacology 20070501

• Site-directed mutagenesis of two aromatic residues lining the active site pocket of the yeast Ltp1.

  Biochimica et biophysica acta 20070501

• Quantitative evaluation of human delta opioid receptor desensitization using the operational model of drug action.

  Molecular pharmacology 20070501

• S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila.

  Journal of neuroscience research 20070501

• Mapping of the structural determinants of artificial and biological membrane damaging activities of a Lys49 phospholipase A2 by scanning alanine mutagenesis.

  Biochimica et biophysica acta 20070501

• Matrix metalloproteinase-9 regulates TNF-alpha and FasL expression in neuronal, glial cells and its absence extends life in a transgenic mouse model of amyotrophic lateral sclerosis.

  Experimental neurology 20070501

• Solid-state nuclear magnetic resonance measurements of HIV fusion peptide to lipid distances reveal the intimate contact of beta strand peptide with membranes and the proximity of the Ala-14-Gly-16 region with lipid headgroups.

  Biochemistry 20070501

• Probing the oxygen-binding site of the human formylglycine-generating enzyme using halide ions.

  Acta crystallographica. Section D, Biological crystallography 20070501

• RF refocused echoes of J-coupled spin systems: effects on RARE-based spectroscopic imaging.

  Magnetic resonance in medicine 20070501

• Structure of cymbidine A, a monomeric peptidoglycan-related compound with hypotensive and diuretic activities, isolated from a higher plant, Cymbidium goeringii (Orchidaceae).

  Chemical & pharmaceutical bulletin 20070501

• ALK-mediated Na+/H+ exchanger-dependent intracellular alkalinization: does it matter for oncogenesis?

  Haematologica 20070501

• The Ala53Thr mutation in the alpha-synuclein gene in a Korean family with Parkinson disease.

  Clinical genetics 20070501

• Relative output factor and beam profile measurements of small radiation fields with an L-alanine/K-band EPR minidosimeter.

  Medical physics 20070501

• Long-term, repeated dose in vitro neurotoxicity of the glutamate receptor antagonist L-AP3, demonstrated in rat hippocampal slice cultures by using continuous propidium iodide incubation.

  Alternatives to laboratory animals : ATLA 20070501

• Minimum free energy pathways and free energy profiles for conformational transitions based on atomistic molecular dynamics simulations.

  The Journal of chemical physics 20070428

• Electrostatics of proteins in dielectric solvent continua. II. First applications in molecular dynamics simulations.

  The Journal of chemical physics 20070428

• L-alanine in a droplet of water: a density-functional molecular dynamics study.

  The journal of physical chemistry. B 20070426

• Aristaless-related homeobox gene, the gene responsible for West syndrome and related disorders, is a Groucho/transducin-like enhancer of split dependent transcriptional repressor.

  Neuroscience 20070425

• Identification of an in vivo inhibitor of Bacillus anthracis spore germination.

  The Journal of biological chemistry 20070420

• Novel triphosphate phosphohydrolase activity of Clostridium thermocellum TTM, a member of the triphosphate tunnel metalloenzyme superfamily.

  The Journal of biological chemistry 20070420

• Hydrophobic surface burial is the major stability determinant of a flat, single-layer beta-sheet.

  Journal of molecular biology 20070420

• Immunohistochemical localization of D-alanine to beta-cells in rat pancreas.

  Biochemical and biophysical research communications 20070420

• The cold denatured state is compact but expands at low temperatures: hydrodynamic properties of the cold denatured state of the C-terminal domain of L9.

  Journal of molecular biology 20070420

• Unveiling hidden catalytic contributions of the conserved His/Trp-III in tyrosine recombinases: assembly of a novel active site in Flp recombinase harboring alanine at this position.

  Journal of molecular biology 20070420

• Ala657 and conserved active site residues promote fibroblast activation protein endopeptidase activity via distinct mechanisms of transition state stabilization.

  Biochemistry 20070417

• Rhenium analogues of promising renal imaging agents with a [99mTc(CO)3]+ core bound to cysteine-derived dipeptides, including lanthionine.

  Inorganic chemistry 20070416

• Pathway of biogenesis of apolipoprotein E-containing HDL in vivo with the participation of ABCA1 and LCAT.

  The Biochemical journal 20070415

• An improved algorithm for analytical gradient evaluation in resolution-of-the-identity second-order Møller-Plesset perturbation theory: application to alanine tetrapeptide conformational analysis.

  Journal of computational chemistry 20070415

• An ant algorithm for the conformational analysis of flexible molecules.

  Journal of computational chemistry 20070415

• Association between the MnSOD Ala-9Val polymorphism and development of schizophrenia and abnormal involuntary movements in the Xhosa population.

  Progress in neuro-psychopharmacology & biological psychiatry 20070413

• Identification of residues critical for the function of the Vibrio cholerae virulence regulator ToxT by scanning alanine mutagenesis.

  Journal of molecular biology 20070413

• Interpretation of synchrotron radiation circular dichroism spectra of anionic, cationic, and zwitterionic dialanine forms.

  The journal of physical chemistry. A 20070412

• Role of proteolysis in caspase-8 activation and stabilization.

  Biochemistry 20070410

• A concise stereoselective synthesis of orthogonally protected lanthionine and beta-methyllanthionine.

  Organic & biomolecular chemistry 20070407

• Sequence variants within exon 1 of MECP2 occur in females with mental retardation.

  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20070405

• Synthesis and pharmacological characterization of N3-substituted willardiine derivatives: role of the substituent at the 5-position of the uracil ring in the development of highly potent and selective GLUK5 kainate receptor antagonists.

  Journal of medicinal chemistry 20070405

• Examination of the folding of a short alanine-based helical peptide with salt bridges using molecular dynamics simulation.

  The journal of physical chemistry. B 20070405

• Predominantly buried residues in the response regulator Spo0F influence specific sensor kinase recognition.

  FEBS letters 20070403

• Similarities and differences between azomethines and ketimines: synthesis, materials characterization and structure of novel imines compounds.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070401

• Ab-initio and density functional study of L- and D-forms of alanine and serine in gas phase and bulk aqueous medium.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070401

• Amino acids in the COOH-terminal region of the oxytocin receptor third intracellular domain are important for receptor function.

  American journal of physiology. Endocrinology and metabolism 20070401

• ESR response to gamma-rays of alanine pellets containing B(OH)3 or Gd2O3.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20070401

• Distinct clinical and pathological features are associated with the BRAF(T1799A(V600E)) mutation in primary melanoma.

  The Journal of investigative dermatology 20070401

• Diazenedicarboxamides as inhibitors of D-alanine-D-alanine ligase (Ddl).

  Bioorganic & medicinal chemistry letters 20070401

• Bacterial expression and characterization of molluscan IDO-like myoglobin.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20070401

• LDL resistance to oxidation: effects of lipid phenotype, autologous HDL and alanine.

  Clinica chimica acta; international journal of clinical chemistry 20070401

• In vitro trans-translation of Thermus thermophilus: ribosomal protein S1 is not required for the early stage of trans-translation.

  RNA (New York, N.Y.) 20070401

• Neonatal hypoxic preconditioning involves vascular endothelial growth factor.

  Neurobiology of disease 20070401

• Determination of the backbone torsion psi angle by tensor correlation of chemical shift anisotropy and heteronuclear dipole-dipole interaction.

  Solid state nuclear magnetic resonance 20070401

• Cold exposure and associated metabolic changes in adult tropical beetles exposed to fluctuating thermal regimes.

  The FEBS journal 20070401

• Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase.

  Journal of inherited metabolic disease 20070401

• Cloning and identification of a gene encoding spore cortex-lytic enzyme in Bacillus thuringiensis.

  Current microbiology 20070401

• Lack of association between serum adiponectin levels and the Pro12Ala polymorphism in Asian Indians.

  Diabetic medicine : a journal of the British Diabetic Association 20070401

• Rebamipide contributes to reducing adverse effects of long-term administration of omeprazole in rats.

  Digestive diseases and sciences 20070401

• Ethanol-mediated oxidative changes in blood lipids and proteins are reversed by aspirin-like drugs.

  Archives of medical research 20070401

• Formation of 5-hydroxymethyl-2-furfural (HMF) and 5-hydroxymethyl-2-furoic acid during roasting of coffee.

  Molecular nutrition & food research 20070401

• Enhanced NFATc1 nuclear occupancy causes T cell activation independent of CD28 costimulation.

  Journal of immunology (Baltimore, Md. : 1950) 20070401

• Synergistic relationship between hyperglycaemia and inflammation with respect to clinical outcomes in non-ST-elevation acute coronary syndromes: analyses from OPUS-TIMI 16 and TACTICS-TIMI 18.

  European heart journal 20070401

• Cross polarization via the non-Zeeman spin reservoirs under MAS.

  Solid state nuclear magnetic resonance 20070401

• Lack of association between pseudoexfoliation syndrome and manganese superoxide dismutase polymorphism.

  Current eye research 20070401

• [Chemical constituents from leaves of Morus multicaulis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070401

• The G1422A variant of the cannabinoid receptor gene (CNR1) is associated with abdominal adiposity in obese men.

  Endocrine 20070401

• Counteracting expression deficiencies by anticipating posttranslational modification of PaHNL5-L1Q-A111G by genetic engineering.

  Journal of biotechnology 20070330

• Metadynamics in essential coordinates: free energy simulation of conformational changes.

  The journal of physical chemistry. B 20070329

• Pre-steady-state currents in neutral amino acid transporters induced by photolysis of a new caged alanine derivative.

  Biochemistry 20070327

• Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.

  The Journal of biological chemistry 20070323

• Functional analysis of mutations in the putative binding site for cystic fibrosis transmembrane conductance regulator potentiators. Interaction between activation and inhibition.

  The Journal of biological chemistry 20070323

• Capillary electrophoretic analysis of gamma-aminobutyric acid and alanine in tea with in-capillary derivatization and fluorescence detection.

  Journal of agricultural and food chemistry 20070321

• Step-wise and pre-organization induced synthesis of a crossed alkene-bridged nisin Z DE-ring mimic by ring-closing metathesis.

  Organic & biomolecular chemistry 20070321

• Double-mutant cycle scanning of the interaction of a peptide ligand and its G protein-coupled receptor.

  Biochemistry 20070320

• Probing the molecular dynamics of the ABC multidrug transporter LmrA by deuterium solid-state nuclear magnetic resonance.

  Biochemistry 20070320

• Identification of a basic region on tissue factor that interacts with the first epidermal growth factor-like domain of factor X.

  Biochemistry 20070320

• Specificity of the deoxyhypusine hydroxylase-eukaryotic translation initiation factor (eIF5A) interaction: identification of amino acid residues of the enzyme required for binding of its substrate, deoxyhypusine-containing eIF5A.

  The Journal of biological chemistry 20070316

• Structure-activity relationship studies on quorum sensing ComX(RO-E-2) pheromone.

  Bioorganic & medicinal chemistry letters 20070315

• Hot spot occlusion from bulk water: a comprehensive study of the complex between the lysozyme HEL and the antibody FVD1.3.

  The journal of physical chemistry. B 20070315

• Covalent catalysis by pyridoxal: evaluation of the effect of the cofactor on the carbon acidity of glycine.

  Journal of the American Chemical Society 20070314

• A highly conformationally specific alpha- and beta-Ala+ decarboxylation pathway.

  Chemical communications (Cambridge, England) 20070314

• A tightly packed hydrophobic cluster directs the formation of an off-pathway sub-millisecond folding intermediate in the alpha subunit of tryptophan synthase, a TIM barrel protein.

  Journal of molecular biology 20070309

• Characterisation of the role of zinc in the hepatitis C virus NS2/3 auto-cleavage and NS3 protease activities.

  Journal of molecular biology 20070309

• Structural and thermal characterization of a semiorganic NLO material: L-alanine cadmium chloride.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070301

• Glucagon chronically impairs hepatic and muscle glucose disposal.

  American journal of physiology. Endocrinology and metabolism 20070301

• AlphaIIbbeta3 priming and clustering by orally active and intravenous integrin antagonists.

  Journal of thrombosis and haemostasis : JTH 20070301

• Increased alanine concentration is associated with exposure to fenitrothion but not carbamates in Chironomus riparius larvae.

  Ecotoxicology and environmental safety 20070301

• The putative transmembrane segment 7 of human organic anion transporter hOAT1 dictates transporter substrate binding and stability.

  The Journal of pharmacology and experimental therapeutics 20070301

• Structural and functional effects of disease-causing amino acid substitutions affecting residues Ala72 and Glu76 of the protein tyrosine phosphatase SHP-2.

  Proteins 20070301

• Aquaporin-11 containing a divergent NPA motif has normal water channel activity.

  Biochimica et biophysica acta 20070301

• Taxol induced apoptosis regulates amino acid transport in breast cancer cells.

  Apoptosis : an international journal on programmed cell death 20070301

• Application of NMR-based metabonomics in the investigation of myocardial ischemia-reperfusion, ischemic preconditioning and antioxidant intervention in rabbits.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070301

• Dominance of amyloid precursor protein sequence over host cell secretases in determining beta-amyloid profiles studies of interspecies variation and drug action by internally standardized immunoprecipitation/mass spectrometry.

  The Journal of pharmacology and experimental therapeutics 20070301

• Alanine scanning mutational analysis of the ligand binding pocket of the human Vitamin D receptor.

  The Journal of steroid biochemistry and molecular biology 20070301

• Role of aspartate 400, arginine 262, and arginine 401 in the catalytic mechanism of human coproporphyrinogen oxidase.

  Protein science : a publication of the Protein Society 20070301

• Analysis of ligand binding to a ribose biosensor using site-directed mutagenesis and fluorescence spectroscopy.

  Protein science : a publication of the Protein Society 20070301

• Evidence that late-endosomal SNARE multimerization complex is promoted by transmembrane segments.

  Biochimica et biophysica acta 20070301

• Syringopeptin SP25A-mediated killing of gram-positive bacteria and the role of teichoic acid d-alanylation.

  FEMS microbiology letters 20070301

• Synaptic plasma membrane Na(+), K (+)-ATPase activity is significantly reduced by the alpha-keto acids accumulating in maple syrup urine disease in rat cerebral cortex.

  Metabolic brain disease 20070301

• Alanine aminotransferase catalyses the breakdown of alanine after hypoxia in Arabidopsis thaliana.

  The Plant journal : for cell and molecular biology 20070301

• Radiative and non-radiative charge recombination pathways in Photosystem II studied by thermoluminescence and chlorophyll fluorescence in the cyanobacterium Synechocystis 6803.

  Biochimica et biophysica acta 20070301

• [Molecular mechanism of trans-translation].

  Seikagaku. The Journal of Japanese Biochemical Society 20070301

• Analysis of monoethanolamine by derivatization with Marfey's reagent and HPLC.

  Journal of chromatographic science 20070301

• Inhibition of kainate receptors reduces the frequency of hippocampal theta oscillations.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070227

• On the use of local diffusion models for path ensemble averaging in potential of mean force computations.

  The Journal of chemical physics 20070227

• Cryptochrome 3 from Arabidopsis thaliana: structural and functional analysis of its complex with a folate light antenna.

  Journal of molecular biology 20070223

• Acidic pH-induced conformational changes in amyloidogenic mutant transthyretin.

  Journal of molecular biology 20070223

• A molecular dynamics study of the correlations between solvent-accessible surface, molecular volume, and folding state.

  The journal of physical chemistry. B 20070222

• Conformational entropy of alanine versus glycine in protein denatured states.

  Proceedings of the National Academy of Sciences of the United States of America 20070220

• How a small change in retinal leads to G-protein activation: initial events suggested by molecular dynamics calculations.

  Proteins 20070215

• Bending elasticity of anti-parallel beta-sheets.

  Biophysical journal 20070215

• Enhanced sampling of peptide and protein conformations using replica exchange simulations with a peptide backbone biasing-potential.

  Proteins 20070215

• Secondary structures of peptides and proteins via NMR chemical-shielding anisotropy (CSA) parameters.

  Journal of the American Chemical Society 20070214

• Free energy of transition for the individual alkaline conformers of yeast iso-1-cytochrome c.

  Biochemistry 20070213

• Conformations of alanine-based peptides in water probed by FTIR, Raman, vibrational circular dichroism, electronic circular dichroism, and NMR spectroscopy.

  Biochemistry 20070213

• Concerted action of exonuclease and Gap-dependent endonuclease activities of FEN-1 contributes to the resolution of triplet repeat sequences (CTG)n- and (GAA)n-derived secondary structures formed during maturation of Okazaki fragments.

  The Journal of biological chemistry 20070209

• Structure and dynamics of the homologous series of alanine peptides: a joint molecular dynamics/NMR study.

  Journal of the American Chemical Society 20070207

• Interleukin-18 mediated inhibition of LTP in the rat dentate gyrus is attenuated in the presence of mGluR antagonists.

  Neuroscience letters 20070202

• Analysis of amino acids in the beta7-beta8 loop of human immunodeficiency virus type 1 reverse transcriptase for their role in virus replication.

  Journal of molecular biology 20070202

• Identification of mammalian mitochondrial proteins that interact with IAPs via N-terminal IAP binding motifs.

  Cell death and differentiation 20070201

• Peroxisome proliferator-activated [corrected] receptor-gamma2 [corrected] Pro12Ala, interaction with alcohol intake and NSAID use, in relation to risk of breast cancer in a prospective study of Danes.

  Carcinogenesis 20070201

• Quantification of serine enantiomers in rat brain microdialysate using Marfey's reagent and LC/MS/MS.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070201

• Determination of the gas-phase acidities of cysteine-polyalanine peptides using the extended kinetic method.

  Journal of the American Society for Mass Spectrometry 20070201

• Utilization of glutamate/creatine ratios for proton spectroscopic diagnosis of meningiomas.

  Neuroradiology 20070201

• Effect of the amino acid alanine on glucagon secretion in non-diabetic and type 1 diabetic subjects during hyperinsulinaemic euglycaemia, hypoglycaemia and post-hypoglycaemic hyperglycaemia.

  Diabetologia 20070201

• Is glycine a surrogate for a D-amino acid in the collagen triple helix?

  Protein science : a publication of the Protein Society 20070201

• Computational alanine scanning mutagenesis--an improved methodological approach.

  Journal of computational chemistry 20070201

• Involvement of alanine 103 residue in kinetic and physicochemical properties of glucose isomerases from Streptomyces species.

  Biotechnology journal 20070201

• Mutations in HOXD13 underlie syndactyly type V and a novel brachydactyly-syndactyly syndrome.

  American journal of human genetics 20070201

• Nitric oxide promotes endothelial cell survival signaling through S-nitrosylation and activation of dynamin-2.

  Journal of cell science 20070201

• Functional P2X7 receptor polymorphisms (His155Tyr, Arg307Gln, Glu496Ala) in patients with Crohn's disease.

  Scandinavian journal of immunology 20070201

• Genetic variation in thrombin-activatable fibrinolysis inhibitor (TAFI) is associated with the risk of splanchnic vein thrombosis.

  Thrombosis and haemostasis 20070201

• Ileal cancer and erosions in the small intestine revealed by capsule endoscopy.

  Endoscopy 20070201

• Neutral Na-amino acid cotransport is differentially regulated by glucocorticoids in the normal and chronically inflamed rabbit small intestine.

  American journal of physiology. Gastrointestinal and liver physiology 20070201

• Rebamipide enema therapy as a treatment for patients with active distal ulcerative colitis.

  Journal of gastroenterology and hepatology 20070201

• Inhibition of Rhizomucor miehei and Candida rugosa lipases by D-glucose in esterification between L-alanine and D-glucose.

  Journal of bioscience and bioengineering 20070201

• Alanine racemase from Helicobacter pylori NCTC 11637: purification, characterization and gene cloning.

  Life sciences 20070130

• Formation of left-handed helices in hybrid peptide oligomers with cis beta-sugar amino acid and L-Ala as building blocks.

  Chemical communications (Cambridge, England) 20070128

• Structure-activity relationships of cyclic peptide-based chemokine receptor CXCR4 antagonists: disclosing the importance of side-chain and backbone functionalities.

  Journal of medicinal chemistry 20070125

• Polypeptide motions are dominated by peptide group oscillations resulting from dihedral angle correlations between nearest neighbors.

  Biochemistry 20070123

• Binding hot spots in the TEM1-BLIP interface in light of its modular architecture.

  Journal of molecular biology 20070119

• Mechanism of intracellular block of the KcsA K+ channel by tetrabutylammonium: insights from X-ray crystallography, electrophysiology and replica-exchange molecular dynamics simulations.

  Journal of molecular biology 20070119

• Ankyrin-G and beta2-spectrin collaborate in biogenesis of lateral membrane of human bronchial epithelial cells.

  The Journal of biological chemistry 20070119

• Identification and characterization of single chain anti-cocaine catalytic antibodies.

  Journal of molecular biology 20070119

• The flexible N-terminal domain of ribosomal protein L11 from Escherichia coli is necessary for the activation of stringent factor.

  Journal of molecular biology 20070119

• Glutamine gluconeogenesis in the small intestine of 72 h-fasted adult rats is undetectable.

  The Biochemical journal 20070115

• Evaluation of the influence of protein precipitation prior to on-line SPE-LC-API/MS procedures using multivariate data analysis.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070115

• Ala394Thr polymorphism in the clock gene NPAS2: a circadian modifier for the risk of non-Hodgkin's lymphoma.

  International journal of cancer 20070115

• Regulation of the arsenic-responsive transcription factor Yap8p involves the ubiquitin-proteasome pathway.

  Journal of cell science 20070115

• Altered specificity of a AAA+ protease.

  Molecular cell 20070112

• (alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions.

  Journal of the American Chemical Society 20070110

• Site-directed mutagenesis in the fingers subdomain of HIV-1 reverse transcriptase reveals a specific role for the beta3-beta4 hairpin loop in dNTP selection.

  Journal of molecular biology 20070105

• Site-directed mutagenesis of conserved aromatic residues in rat squalene epoxidase.

  Biochemical and biophysical research communications 20070105

• Parkinson syndrome, neuropathy, and myopathy caused by the mutation A8344G (MERRF) in tRNALys.

  Neurology 20070102

• Acute effects of isolated and combined L-alanine and L-glutamine on hepatic gluconeogenesis, ureagenesis and glycaemic recovery in experimental short-term insulin induced hypoglycaemia.

  Cell biochemistry and function 20070101

• CCR5 interactions with the variable 3 loop of gp120.

  Journal of molecular modeling 20070101

• Simultaneous substitution of Gly96 to Ala and Ala183 to Thr in 5-enolpyruvylshikimate-3-phosphate synthase gene of E. coli (k12) and transformation of rapeseed (Brassica napus L.) in order to make tolerance to glyphosate.

  Plant cell reports 20070101

• Effects of metal ion and solute conformation change on hydration of small amino acid.

  Biophysical chemistry 20070101

• The alanine/threonine polymorphism of the alpha-1-antichymotrypsin (SERPINA3) gene and ruptured intracranial aneurysms in the Japanese population.

  Cerebrovascular diseases (Basel, Switzerland) 20070101

• Hepatic and muscle insulin action during late pregnancy in the dog.

  American journal of physiology. Regulatory, integrative and comparative physiology 20070101

• Complex glutamate labeling from [U-13C]glucose or [U-13C]lactate in co-cultures of cerebellar neurons and astrocytes.

  Neurochemical research 20070101

• The organic osmolytes betaine and proline are transported by a shared system in early preimplantation mouse embryos.

  Journal of cellular physiology 20070101

• Polyisocyanides derived from tripeptides of alanine.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

• Effect of pH, urea, peptide length, and neighboring amino acids on alanine alpha-proton random coil chemical shifts.

  Biopolymers 20070101

• Ethanol inhibits cold-menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4,5-bisphosphate.

  Journal of neurochemistry 20070101

• Stereoselective determination of benalaxyl in plasma by chiral high-performance liquid chromatography with diode array detector and application to pharmacokinetic study in rabbits.

  Chirality 20070101

• Defining a binding pocket for sulfonylureas in ATP-sensitive potassium channels.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070101

• Multilocus analyses of Renin-Angiotensin-aldosterone system gene variants on blood pressure at rest and during behavioral stress in young normotensive subjects.

  Hypertension (Dallas, Tex. : 1979) 20070101

• Membrane topology of aspartate:alanine antiporter AspT from Comamonas testosteroni.

  Journal of biochemistry 20070101

• Rebamipide inhibits gastric cancer cell growth.

  Digestive diseases and sciences 20070101

• Effect of rebamipide on the colonic barrier in interleukin-10-deficient mice.

  Digestive diseases and sciences 20070101

• Investigations into the in vitro antimicrobial activity and mode of action of the phenazine antibiotic D-alanylgriseoluteic acid.

  International journal of antimicrobial agents 20070101

• A functional polymorphism in the manganese superoxide dismutase gene and diabetic nephropathy.

  Diabetes 20070101

• Safinamide.

  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070101

• Alanine-glutamine dipeptide (AGD) inhibits expression of inflammation-related genes in hemorrhagic shock.

  JPEN. Journal of parenteral and enteral nutrition 20070101

• The Pro12Ala polymorphism in PPARgamma2 gene affects lipid parameters in Greek primary school children: A case of gene-to-gender interaction.

  The American journal of the medical sciences 20070101

• Effect of oculopharyngeal muscular dystrophy-associated extension of seven alanines on the fibrillation properties of the N-terminal domain of PABPN1.

  The FEBS journal 20070101

• A family of stage-specific alanine-rich proteins on the surface of epimastigote forms of Trypanosoma brucei.

  Molecular microbiology 20070101

• A synthetic gag p24 epitope chemically coupled to BSA through a decaalanine peptide enhances HIV type 1 serodiagnostic ability by several folds.

  AIDS research and human retroviruses 20070101

• The +4G site in Kozak consensus is not related to the efficiency of translation initiation.

  PloS one 20070101

• The CDKN2a common variants: 148 Ala/Thr and 500 C/G in 3' UTR, and their association with clinical course of melanoma.

  Acta biochimica Polonica 20070101

• Conserved aspartic acid 233 and alanine 231 are not required for poliovirus polymerase function in replicons.

  Virology journal 20070101

• Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism is associated with the susceptibility to ischemic stroke in Taeeumin classified by Sasang medicine.

  Neurological research 20070101

• Response of alanine and radio-photo-luminescence dosemeters to mixed high-energy radiation fields.

  Radiation protection dosimetry 20070101

• Labeling, detection and identification of newly synthesized proteomes with bioorthogonal non-canonical amino-acid tagging.

  Nature protocols 20070101

• The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: understanding the determinants of binding affinity by comparison with Abl-SH3.

  BMC structural biology 20070101

• Pesticide retention in an experimental wetland treating non-point source pollution from agriculture runoff.

  Water science and technology : a journal of the International Association on Water Pollution Research 20070101

• Flexibility in energy metabolism supports hypoxia tolerance in Drosophila flight muscle: metabolomic and computational systems analysis.

  Molecular systems biology 20070101

• Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene is associated with greater insulin sensitivity and decreased risk of type 2 diabetes in an Iranian population.

  Clinical chemistry and laboratory medicine 20070101

• Sequence, 'subtle' alternative splicing and expression of the CYYR1 (cysteine/tyrosine-rich 1) mRNA in human neuroendocrine tumors.

  BMC cancer 20070101

• Increased inhibitory capacity of an anti-C5a complementary peptide following acetylation of N-terminal alanine.

  Microbiology and immunology 20070101

• NMR-based fluxomics: quantitative 2D NMR methods for isotopomers analysis.

  Phytochemistry 20070101

• Alanine racemase from the green alga Chlamydomonas reinhardtii.

  Amino acids 20070101

• Aard is specifically up-regulated in Sertoli cells during mouse testis differentiation.

  The International journal of developmental biology 20070101

• Peroxisome proliferator-activated receptor gamma polymorphism Pro12Ala is associated with nephropathy in type 2 diabetes.

  Journal of diabetes and its complications 20070101

• Copper (II) complexes with Ac-HXH-NHMe (X=Gly, Ala and Aib) peptide motifs: influence of increasing CH(3) groups at C(alpha) of residue X on the coordination in solution.

  Protein and peptide letters 20070101

• Purification and preliminary crystallization of alanine racemase from Streptococcus pneumoniae.

  BMC microbiology 20070101

• Parallel determination of enzyme activities and in vivo fluxes in Brassica napus embryos grown on organic or inorganic nitrogen source.

  Phytochemistry 20070101

• Alanine blends for ESR measurements of thermal neutron fluence in a mixed radiation field.

  Radiation protection dosimetry 20070101

• Quantification of the effects of a ryanodine receptor channel mutation on interaction with a ryanoid.

  Molecular membrane biology 20070101

• Kv1 potassium channel C-terminus constant HRETE region: arginine substitution affects surface protein level and conductance level of subfamily members differentially.

  Molecular membrane biology 20070101

• OCA2 481Thr, a hypofunctional allele in pigmentation, is characteristic of northeastern Asian populations.

  Journal of human genetics 20070101

• Phase selection of calcium carbonate through the chirality of adsorbed amino acids.

  Angewandte Chemie (International ed. in English) 20070101

• Nuclear localization signals of the E-cadherin transcriptional repressor Snail.

  Cells, tissues, organs 20070101

• Polymorphism of the FABP2 gene: a population frequency analysis and an association study with cardiovascular risk markers in Argentina.

  BMC medical genetics 20070101

• BACE1 and mutated presenilin-1 differently modulate Abeta40 and Abeta42 levels and cerebral amyloidosis in APPDutch transgenic mice.

  Neuro-degenerative diseases 20070101

• [Carnosine--biological activity and perspectives in pharmacotherapy].

  Wiadomosci lekarskie (Warsaw, Poland : 1960) 20070101

• TonB/TolA amino-terminal domain modeling.

  Methods in enzymology 20070101

• Novel mutations in the FOXC1 gene in Japanese patients with Axenfeld-Rieger syndrome.

  Molecular vision 20070101

• Substitution of conserved cysteine residues in wheat streak mosaic virus HC-Pro abolishes virus transmission by the wheat curl mite.

  Archives of virology 20070101

• A biosynthetic route to dehydroalanine-containing proteins.

  Angewandte Chemie (International ed. in English) 20070101

• Preparation of the functionalizable methionine surrogate azidohomoalanine via copper-catalyzed diazo transfer.

  Nature protocols 20070101

• Synthesis of the functionalizable methionine surrogate azidohomoalanine using Boc-homoserine as precursor.

  Nature protocols 20070101

• Calorimetric investigation of phosphorylated and non-phosphorylated peptide ligand binding to the human Grb7-SH2 domain.

  Journal of molecular recognition : JMR 20070101

• Molecular mechanism of the sea anemone toxin ShK recognizing the Kv1.3 channel explored by docking and molecular dynamic simulations.

  Journal of chemical information and modeling 20070101

• Evidence for the 3 10-helical structure of peptides based on antAib, a fluorophoric, anthracene-fused, 1-aminocyclopentane-1-carboxylic acid.

  Biopolymers 20070101

• A genetically encoded bidentate, metal-binding amino acid.

  Angewandte Chemie (International ed. in English) 20070101

• X-ray structures of two proteins belonging to Pfam DUF178 revealed unexpected structural similarity to the DUF191 Pfam family.

  BMC structural biology 20070101

• An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides.

  PloS one 20070101

• [Equilibrium unfolding of mutant apomyoglobins with substitutions of conserved nonfunctional residues by alanine].

  Molekuliarnaia biologiia 20070101

• Spin relaxation enhancement confirms dominance of extended conformations in short alanine peptides.

  Angewandte Chemie (International ed. in English) 20070101

• Identification of TyeA residues required to interact with YopN and to regulate Yop secretion.

  Advances in experimental medicine and biology 20070101

• An RNA polymerase III-dependent heterochromatin barrier at fission yeast centromere 1.

  PloS one 20070101

• Intein-mediated peptide arrays for epitope mapping and kinase/phosphatase assays.

  Methods in molecular biology (Clifton, N.J.) 20070101

• Molecular dynamics simulation of human LOX-1 provides an explanation for the lack of OxLDL binding to the Trp150Ala mutant.

  BMC structural biology 20070101

• ABCA4 mutations and discordant ABCA4 alleles in patients and siblings with bull's-eye maculopathy.

  The British journal of ophthalmology 20070101

• Solid-phase synthesis and properties of chiral peptide nucleic acids bearing cationic side chains.

  Nucleic acids symposium series (2004) 20070101

• Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?

  Breast cancer research : BCR 20070101

• Freezing effect on chirality generation of DL-alanine-N-carboxy-anhydride oligomerization in aqueous solution.

  Protein and peptide letters 20070101

• Synpolydactyly and HOXD13 polyalanine repeat: addition of 2 alanine residues is without clinical consequences.

  BMC medical genetics 20070101

• Functional reconstruction and synthetic mimicry of a conformational epitope using CLIPS technology.

  Journal of molecular recognition : JMR 20070101

• Safety, tolerability, and effects on plasma and cerebrospinal fluid amyloid-beta after inhibition of gamma-secretase.

  Clinical neuropharmacology 20070101

• Maize nitrilases have a dual role in auxin homeostasis and beta-cyanoalanine hydrolysis.

  Journal of experimental botany 20070101

• [Frequency of the Pro 12Ala polymorphism of PPARgamma2 gene in Ukrainian population and its possible role in development of metabolic syndrome].

  TSitologiia i genetika 20070101

• Importance of novel sequence alterations in the FHIT gene on formation of breast cancer.

  Tumori 20070101

• Effect of taurine on the concentrations of glutamate, GABA, glutamine and alanine in the rat striatum and hippocampus.

  Proceedings of the Western Pharmacology Society 20070101

• Field amplified sample stacking coupled with chip-based capillary electrophoresis using negative pressure sample injection technique.

  Journal of chromatography. A 20061229

• Synthesis of low-hemolytic antimicrobial dehydropeptides based on gramicidin s.

  Journal of medicinal chemistry 20061228

• No association between Ala9Val functional polymorphism of MnSOD gene and schizophrenia in a representative Italian sample.

  Neuroscience letters 20061227

• Elucidation of hydrolysis mechanisms for fatty acid amide hydrolase and its Lys142Ala variant via QM/MM simulations.

  Journal of the American Chemical Society 20061227

• The catalytic role of the copper ligand H172 of peptidylglycine alpha-hydroxylating monooxygenase: a kinetic study of the H172A mutant.

  Biochemistry 20061226

• Functional role of the conserved active site proline of triosephosphate isomerase.

  Biochemistry 20061226

• Mechanistic studies of the flavoenzyme tryptophan 2-monooxygenase: deuterium and 15N kinetic isotope effects on alanine oxidation by an L-amino acid oxidase.

  Biochemistry 20061226

• EPR dosimetry of radiotherapy photon beams in inhomogeneous media using alanine films.

  Physics in medicine and biology 20061221

• Peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism is associated with reduced risk for ischemic stroke with type 2 diabetes.

  Neuroscience letters 20061220

• Collagen fibers as a chiral agent: A demonstration of stereochemistry effects.

  Journal of the American Chemical Society 20061220

• Methylation of Smad6 by protein arginine N-methyltransferase 1.

  FEBS letters 20061211

• Insight into heme protein redox potential control and functional aspects of six-coordinate ligand-sensing heme proteins from studies of synthetic heme peptides.

  Inorganic chemistry 20061211

• Of folding and function: understanding active-site context through metalloenzyme design.

  Inorganic chemistry 20061211

• Computational study of iron(II) and -(III) complexes with a simple model human H ferritin ferroxidase center.

  Inorganic chemistry 20061211

• Two-component polypeptides modeled with effective pair potentials.

  The journal of physical chemistry. B 20061207

• (2R)- and (2S)-3-fluoroalanine and their N-methyl derivatives: synthesis and incorporation in peptide scaffolds.

  Organic letters 20061207

• Vibrational spectroscopic characteristics of secondary structure polypeptides in liquid water: constrained MD simulation studies.

  Biopolymers 20061205

• The interplay of sequence and stereochemistry in defining conformation in proteins and polypeptides.

  Biopolymers 20061205

• N- and C-terminal hydrophobic patches are involved in fibrillation of glucagon.

  Biochemistry 20061205

• Expression, purification and characterization of factor IX derivatives using a novel vector system.

  Protein expression and purification 20061201

• Structure of the progesterone receptor-deoxyribonucleic acid complex: novel interactions required for binding to half-site response elements.

  Molecular endocrinology (Baltimore, Md.) 20061201

• Selection and characterisation of a xylitol-derepressed Aspergillus niger mutant that is apparently impaired in xylitol transport.

  Applied microbiology and biotechnology 20061201

• Studies to investigate the in vivo therapeutic window of the gamma-secretase inhibitor N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide (LY411,575) in the CRND8 mouse.

  The Journal of pharmacology and experimental therapeutics 20061201

• Structure- and property-based design of factor Xa inhibitors: pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs.

  Bioorganic & medicinal chemistry letters 20061201

• Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase.

  The Journal of biological chemistry 20061201

• Two conserved residues govern the salt and pH dependencies of the binding reaction of a PDZ domain.

  The Journal of biological chemistry 20061201

• Structure of the Escherichia coli O157:H7 heme oxygenase ChuS in complex with heme and enzymatic inactivation by mutation of the heme coordinating residue His-193.

  The Journal of biological chemistry 20061201

• Organic amendments affecting sorption, leaching and dissipation of fungicides in soils.

  Pest management science 20061201

• Structure-guided mutational analysis of T4 RNA ligase 1.

  RNA (New York, N.Y.) 20061201

• Effect of a gastro-protective agent, rebamipide, on symptom improvement in patients with functional dyspepsia: a double-blind placebo-controlled study in Japan.

  Journal of gastroenterology and hepatology 20061201

• Characterization of several amino acid transports and glutamine metabolism in MOLT4 human T4 leukemia cells.

  Clinical and laboratory haematology 20061201

• The roles of three palmitoylation sites of RPE65 in its membrane association and isomerohydrolase activity.

  Investigative ophthalmology & visual science 20061201

• [Trans-translation].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20061201

• Ser46 phosphorylation regulates p53-dependent apoptosis and replicative senescence.

  Cell cycle (Georgetown, Tex.) 20061201

• Assessing the efficacy of famotidine and rebamipide in the treatment of gastric mucosal lesions in patients receiving long-term NSAID therapy (FORCE--famotidine or rebamipide in comparison by endoscopy).

  Journal of gastroenterology 20061201

• Importance of individual side chains for the stability of a protein fold: computational alanine scanning of the insulin monomer.

  Journal of computational chemistry 20061130

• Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue.

  Journal of medicinal chemistry 20061130

• 'Click to chelate': synthesis and installation of metal chelates into biomolecules in a single step.

  Journal of the American Chemical Society 20061129

• N-methylated cyclic pentaalanine peptides as template structures.

  Journal of the American Chemical Society 20061129

• Self-exchange electron transfer in high oxidation state non-oxo metal complexes: amavadin.

  Chemical communications (Cambridge, England) 20061128

• In-situ crosslinkable thermo-responsive hydrogels for drug delivery.

  Journal of controlled release : official journal of the Controlled Release Society 20061128

• Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice.

  Circulation 20061121

• Capillary electrophoresis with electrochemiluminescence detection for measurement of aspartate aminotransferase and alanine aminotransferase activities in biofluids.

  Journal of chromatography. A 20061117

• Nonadiabatic effects in the two-dimensional infrared spectra of peptides: application to alanine dipeptide.

  The journal of physical chemistry. B 20061116

• Quantum mechanical calculation of the effects of stiff and rigid constraints in the conformational equilibrium of the alanine dipeptide.

  Journal of computational chemistry 20061115

• Design, total synthesis, and biological evaluation of neodysiherbaine A derivative as potential probes.

  Bioorganic & medicinal chemistry letters 20061115

• Comparison of multiple Amber force fields and development of improved protein backbone parameters.

  Proteins 20061115

• Molecular dynamics simulations of Hydrogenobacter thermophilus cytochrome c552: comparisons of the wild-type protein, a b-type variant, and the apo state.

  Proteins 20061115

• Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis.

  Cancer research 20061115

• The role of a conserved serine residue within hydrogen bonding distance of FAD in redox properties and the modulation of catalysis by Ca2+/calmodulin of constitutive nitric-oxide synthases.

  The Journal of biological chemistry 20061110

• Mutational analysis of sigma70 region 4 needed for appropriation by the bacteriophage T4 transcription factors AsiA and MotA.

  Journal of molecular biology 20061110

• Self-association of the transmembrane domain of RET underlies oncogenic activation by MEN2A mutations.

  Oncogene 20061109

• Uncertainties in alanine/ESR dosimetry at the Physikalisch-Technische Bundesanstalt.

  Physics in medicine and biology 20061107

• Harmonic Fourier beads method for studying rare events on rugged energy surfaces.

  The Journal of chemical physics 20061107

• A specific dileucine motif is required for the GGA-dependent entry of newly synthesized insulin-responsive aminopeptidase into the insulin-responsive compartment.

  The Journal of biological chemistry 20061103

• Regulation of FNR dimerization by subunit charge repulsion.

  The Journal of biological chemistry 20061103

• Charge transfer study through the determination of the ionization energies of tetrapeptides X3-Tyr, X = Gly, Ala, or Leu. Influence of the inclusion of one glycine in alanine and leucine containing peptides.

  The journal of physical chemistry. A 20061102

• Renin-angiotensin system gene polymorphisms: association with susceptibility to Henoch-Schonlein purpura and renal involvement.

  Clinical rheumatology 20061101

• Presynaptic inhibition by kainate receptors converges mechanistically with presynaptic inhibition by adenosine and GABAB receptors.

  Neuropharmacology 20061101

• Polarization transfer from remote protons in 13C CP/MAS.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20061101

• Concentration-dependent modulation of amyloid-beta in vivo and in vitro using the gamma-secretase inhibitor, LY-450139.

  The Journal of pharmacology and experimental therapeutics 20061101

• Structural determinants for G-protein activation and specificity in the third intracellular loop of the thyroid-stimulating hormone receptor.

  Journal of molecular medicine (Berlin, Germany) 20061101

• Clinical characteristics of paroxysmal nonkinesigenic dyskinesia in Serbian family with Myofibrillogenesis regulator 1 gene mutation.

  Movement disorders : official journal of the Movement Disorder Society 20061101

• Complete alanine scanning of the two-component lantibiotic lacticin 3147: generating a blueprint for rational drug design.

  Molecular microbiology 20061101

• Low doses of tumour necrosis factor alpha and interleukin 1beta diminish hepatic gluconeogenesis from alanine in vivo.

  Basic & clinical pharmacology & toxicology 20061101

• Re: Response of a KIT-positive extra-abdominal fibromatosis to imatinib mesylate and KIT genetic analysis.

  Journal of the National Cancer Institute 20061101

• Desulfotomaculum thermosubterraneum sp. nov., a thermophilic sulfate-reducer isolated from an underground mine located in a geothermally active area.

  International journal of systematic and evolutionary microbiology 20061101

• Substrate specificity of thermostable D-alanine-D-alanine ligase from Thermotoga maritima ATCC 43589.

  Bioscience, biotechnology, and biochemistry 20061101

• Amino acid alanine reactivity with the fingerprint reagent ninhydrin. A detailed ab initio computational study.

  Journal of forensic sciences 20061101

• General structural motifs of amyloid protofilaments.

  Proceedings of the National Academy of Sciences of the United States of America 20061031

• Role of amino acid side chains in region 17-31 of parathyroid hormone (PTH) in binding to the PTH receptor.

  The Journal of biological chemistry 20061027

• Laminin alpha1 chain LG4 module promotes cell attachment through syndecans and cell spreading through integrin alpha2beta1.

  The Journal of biological chemistry 20061027

• Role of Hcn1 and its phosphorylation in fission yeast anaphase-promoting complex/cyclosome function.

  The Journal of biological chemistry 20061027

• Conformational preferences of non-prolyl and prolyl residues.

  The journal of physical chemistry. B 20061026

• The conformation of cyclo(-D-Pro-Ala4-) as a model for cyclic pentapeptides of the DL4 type.

  Journal of the American Chemical Society 20061025

• Structure-based design of potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics.

  Biochemical and biophysical research communications 20061020

• Modeling of folding and unfolding mechanisms in alanine-based alpha-helical polypeptides.

  The journal of physical chemistry. B 20061019

• Infrared line shape of an alpha-carbon deuterium-labeled amino acid.

  Journal of the American Chemical Society 20061018

• Influence of pH and soil copper on adsorption of metalaxyl and penconazole by the surface layer of vineyard soils.

  Journal of agricultural and food chemistry 20061018

• Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma prevention.

  Journal of the National Cancer Institute 20061018

• Synthesis of DL-alanine hollow tubes and core-shell mesostructures.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20061016

• Structural analysis of the regulatory dithiol-containing domain of the chloroplast ATP synthase gamma subunit.

  The Journal of biological chemistry 20061013

• Two separate, conserved acidic amino acid domains within the Toxoplasma gondii MIC2 cytoplasmic tail are required for parasite survival.

  The Journal of biological chemistry 20061013

• Can Raman optical activity separate axial from local chirality? A theoretical study of helical deca-alanine.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20061013

• Cation-pi interaction in the polyolefin cyclization cascade uncovered by incorporating unnatural amino acids into the catalytic sites of squalene cyclase.

  Journal of the American Chemical Society 20061011

• Importance of bile acids for novel oral absorption system containing polyamines to improve intestinal absorption.

  Journal of controlled release : official journal of the Controlled Release Society 20061010

• Safinamide: from molecular targets to a new anti-Parkinson drug.

  Neurology 20061010

• Symptom relief in Parkinson disease by safinamide: Biochemical and clinical evidence of efficacy beyond MAO-B inhibition.

  Neurology 20061010

• Structural and functional characterization of transmembrane segment VII of the Na+/H+ exchanger isoform 1.

  The Journal of biological chemistry 20061006

• Archaeal N-terminal protein maturation commonly involves N-terminal acetylation: a large-scale proteomics survey.

  Journal of molecular biology 20061006

• Macular corneal dystrophy types I and II are caused by distinct mutations in the CHST6 gene in Iceland.

  Molecular vision 20061002

• Spectral investigations of amino acid picrates.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061001

• Preparation of beta-nitroalanine using the Easton three-component coupling method.

  Amino acids 20061001

• Retrovirus producer cell line metabolism: implications on viral productivity.

  Applied microbiology and biotechnology 20061001

• Expression of alr gene from Corynebacterium glutamicum ATCC 13032 in Escherichia coli and molecular characterization of the recombinant alanine racemase.

  Journal of biotechnology 20061001

• Differential changes of group II and group III mGluR function in central amygdala neurons in a model of arthritic pain.

  Journal of neurophysiology 20061001

• Ala45Thr variation in neuroD1 gene is associated with early-onset type 2 diabetes with or without diabetic pedigree in Chinese.

  Molecular and cellular biochemistry 20061001

• Considerations on the lactate consumption by CHO cells in the presence of galactose.

  Journal of biotechnology 20061001

• Arabidopsis SHORT INTEGUMENTS 2 is a mitochondrial DAR GTPase.

  Genetics 20061001

• Staphylococcus aureus adhesion via Spa, ClfA, and SdrCDE to immobilized platelets demonstrates shear-dependent behavior.

  Arteriosclerosis, thrombosis, and vascular biology 20061001

• Free amino acid composition in juveniles of Mytilus galloprovincialis: spatial variability after Prestige oil spill.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20061001

• Interleukin-6 receptor gene polymorphisms and periodontitis in a non-smoking Japanese population.

  Journal of clinical periodontology 20061001

• Fed-batch two-phase production of alanine by a metabolically engineered Escherichia coli.

  Biotechnology letters 20061001

• Manganese superoxide dismutase Ala-9Val polymorphism, environmental modifiers, and risk of breast cancer in a German population.

  Cancer causes & control : CCC 20061001

• PPAR-gamma2 Pro12Ala variant, insulin resistance and plasma long-chain polyunsaturated fatty acids in childhood obesity.

  Pediatric research 20061001

• Fast metabolic imaging of systems with sparse spectra: application for hyperpolarized 13C imaging.

  Magnetic resonance in medicine 20061001

• Novel mechanism of resistance to glycopeptide antibiotics in Enterococcus faecium.

  The Journal of biological chemistry 20061001

• The uptake of amino acids by the cyanobacterium Planktothrix rubescens is stimulated by light at low irradiances.

  FEMS microbiology ecology 20061001

• Breast cancer risk and polymorphisms in genes involved in metabolism of estrogens (CYP17, HSD17beta1, COMT and MnSOD): possible protective role of MnSOD gene polymorphism Val/Ala and Ala/Ala in women that never breast fed.

  Oncology reports 20061001

• Redesign of human carbonic anhydrase II for increased esterase activity and specificity towards esters with long acyl chains.

  Biochimica et biophysica acta 20061001

• Hypofibrinogenaemia associated with common gamma82Ala-->Gly mutation is not mediated by altered mRNA splicing.

  Thrombosis and haemostasis 20061001

• A truncated Bacillus subtilis dal gene with a 3' ssrA gene tag regulates the growth and virulence of racemase-deficient Listeria monocytogenes.

  Microbiology (Reading, England) 20061001

• Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial.

  Journal of thrombosis and thrombolysis 20061001

• Engineering dehydro amino acids and thioethers into peptides using lacticin 481 synthetase.

  Chemistry & biology 20061001

• [Case of drug-induced lung injury due to Rebamipide].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20061001

• Long-term prevention of diabetes and marked suppression of insulin autoantibodies and insulitis in mice lacking native insulin B9-23 sequence.

  Annals of the New York Academy of Sciences 20061001

• Manganese superoxide dismutase (MnSOD: Ala-9Val) gene polymorphism and mood disorders: a preliminary study.

  Progress in neuro-psychopharmacology & biological psychiatry 20060930

• Proximal influences in two-on-two globins: effect of the Ala69Ser replacement on Synechocystis sp. PCC 6803 hemoglobin.

  Biochemistry 20060926

• Aspartic acid 405 contributes to the substrate specificity of aminopeptidase B.

  Biochemistry 20060926

• Unfolding of alanine-based peptides using electron spin resonance distance measurements.

  Biochemistry 20060926

• Interaction of CTSD and A2M polymorphisms in the risk for Alzheimer's disease.

  Journal of the neurological sciences 20060925

• Ground-state structures and vertical excitations for the kindling fluorescent protein asFP595.

  The journal of physical chemistry. B 20060921

• How well does Poisson-Boltzmann implicit solvent agree with explicit solvent? A quantitative analysis.

  The journal of physical chemistry. B 20060921

• Evaluation of vascular endothelial growth factor addition in vitro on mouse inner ear progenitor cell cultures.

  Neuroreport 20060918

• Low-frequency cooperative dynamics in L-, D-, and DL-alanine crystals: a 13C and 15N cross-polarization magic-angle-spinning NMR study.

  The journal of physical chemistry. B 20060914

• The microwave spectrum of a two-top peptide mimetic: the N-acetyl alanine methyl ester molecule.

  The Journal of chemical physics 20060914

• Structures of dense glycine and alanine adlayers on chiral Cu(3,1,17) surfaces.

  Langmuir : the ACS journal of surfaces and colloids 20060912

• Increase of RNase a N-terminus polarity or C-terminus apolarity changes the two domains' propensity to swap and form the two dimeric conformers of the protein.

  Biochemistry 20060912

• DNA-repair gene polymorphisms predict favorable clinical outcome among patients with advanced squamous cell carcinoma of the head and neck treated with cisplatin-based induction chemotherapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060910

• Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration.

  Nature 20060907

• Molecular biology: sticky end in protein synthesis.

  Nature 20060907

• Determination of conformational free energies of peptides by multidimensional adaptive umbrella sampling.

  The Journal of chemical physics 20060907

• Reproducibility and transferability of topological data: experimental charge density study of two modifications of L-alanyl-L-tyrosyl-L-alanine.

  Organic & biomolecular chemistry 20060907

• Relationship between sequence determinants of stability for two natural homologous proteins with different folds.

  Biochemistry 20060905

• Receptor-type PTP-NP inhibition of Dynamin-1 GTPase activity is associated with neuronal depolarization.

  Cellular signalling 20060901

• The Gly146Ala variation in human SF-1 gene: its association with insulin resistance and type 2 diabetes in Chinese.

  Diabetes research and clinical practice 20060901

• Cortisol stimulates system A amino acid transport and SNAT2 expression in a human placental cell line (BeWo).

  American journal of physiology. Endocrinology and metabolism 20060901

• Association between the Pro12Ala variant of the peroxisome proliferator-activated receptor-gamma2 gene and increased 24-h diastolic blood pressure in obese patients with type II diabetes.

  Journal of human hypertension 20060901

• Leucine in food mediates some of the postprandial rise in plasma leptin concentrations.

  American journal of physiology. Endocrinology and metabolism 20060901

• Tricarboxylic acid cycle intermediates accumulate at the onset of intense exercise in man but are not essential for the increase in muscle oxygen uptake.

  Pflugers Archiv : European journal of physiology 20060901

• Broad substrate stereospecificity of the Mycobacterium tuberculosis 7-keto-8-aminopelargonic acid synthase: Spectroscopic and kinetic studies.

  The Journal of biological chemistry 20060901

• Requirement of reversible caldesmon phosphorylation at P21-activated kinase-responsive sites for lamellipodia extensions during cell migration.

  Cell motility and the cytoskeleton 20060901

• Domain structure and DNA binding regions of beta protein from bacteriophage lambda.

  The Journal of biological chemistry 20060901

• Access to organic and insoluble sources of phosphorus varies among soil Chytridiomycota.

  Archives of microbiology 20060901

• Involvement of Clp protease activity in modulating the Bacillus subtilissigmaw stress response.

  Molecular microbiology 20060901

• Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.

  Neuroscience research 20060901

• Cutting edge: Decreased accumulation and regulatory function of CD4+ CD25(high) T cells in human STAT5b deficiency.

  Journal of immunology (Baltimore, Md. : 1950) 20060901

• Gain of function mutants reveal sites important for the interaction of the atypical inhibitors benztropine and bupropion with monoamine transporters.

  Journal of neurochemistry 20060901

• Concise synthesis of enantiopure alpha-trifluoromethyl alanines, diamines, and amino alcohols via the Strecker-type reaction.

  The Journal of organic chemistry 20060901

• S100A8 triggers oxidation-sensitive repulsion of neutrophils.

  Journal of dental research 20060901

• Role of leucine zipper motif in apoE3 N-terminal domain lipid binding activity.

  Biochimica et biophysica acta 20060901

• Associations of a novel IL4RA polymorphism, Ala57Thr, in Greenlander Inuit.

  The Journal of allergy and clinical immunology 20060901

• Juvenile-onset Parkinsonism as a result of the first mutation in the adenosine triphosphate orientation domain of PINK1.

  Archives of neurology 20060901

• Inhibition of lethal endotoxin shock with an L-pyridylalanine containing metalloproteinase inhibitor selected by high-throughput screening of a new peptide library.

  Combinatorial chemistry & high throughput screening 20060901

• Microspheres from new biodegradable poly(ester amide)s with different ratios of L- and D-alanine for controlled drug delivery.

  Journal of microencapsulation 20060901

• Correlation between plasma levels of glutamate, alanine and serine with severity of depression.

  Progress in neuro-psychopharmacology & biological psychiatry 20060830

• Binding and stability determinants of the PPARgamma nuclear receptor-coactivator interface as revealed by shotgun alanine scanning and in vivo selection.

  Journal of the American Chemical Society 20060830

• Asymmetric total syntheses of marine cyclic depsipeptide halipeptins A-D.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060825

• Conformational equilibrium in alanine-rich peptides probed by reversible stretching simulations.

  The journal of physical chemistry. B 20060824

• Two affected siblings with nuclear cataract associated with a novel missense mutation in the CRYGD gene.

  Molecular vision 20060824

• The calcium channel alpha2delta-2 subunit partitions with CaV2.1 into lipid rafts in cerebellum: implications for localization and function.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060823

• Phosphorylation of the norepinephrine transporter at threonine 258 and serine 259 is linked to protein kinase C-mediated transporter internalization.

  The Journal of biological chemistry 20060818

• The absolute structural requirement for a proline in the P3'-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold.

  The Journal of biological chemistry 20060818

• Cooperativity between the hydrophobic and cross-linking domains of elastin.

  The Journal of biological chemistry 20060818

• Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.

  Science (New York, N.Y.) 20060818

• trans-hydroalumination/alkylation: one-pot synthesis of trisubstituted allylic alcohols.

  Organic letters 20060817

• The planar conformation of a strained proline ring: a QM/MM study.

  Proteins 20060815

• Alpha-helix stabilization by alanine relative to glycine: roles of polar and apolar solvent exposures and of backbone entropy.

  Proteins 20060815

• Drosophila nuclear receptor E75 is a thiolate hemoprotein.

  Biochemistry 20060815

• Structure of the O-polysaccharide of Proteus mirabilis CCUG 10705 (OF) containing an amide of D-galacturonic acid with L-alanine.

  Carbohydrate research 20060814

• Group II metabotropic glutamate receptor-mediated regulation of dopamine release from slices of rat nucleus accumbens.

  Neuroscience letters 20060814

• Heparin modulates the 99-loop of factor IXa: effects on reactivity with isolated Kunitz-type inhibitor domains.

  The Journal of biological chemistry 20060811

• Single crystals of L-O-serine phosphate X-irradiated at low temperatures: EPR, ENDOR, EIE, and DFT studies.

  The journal of physical chemistry. A 20060810

• Rhodopsin-interacting surface of the transducin gamma subunit.

  Biochemistry 20060808

• Prognostic utility of heart-type fatty acid binding protein in patients with acute coronary syndromes.

  Circulation 20060808

• Calmodulin isoform-specific activation of a rice calmodulin-binding kinase conferred by only three amino-acids of OsCaM61.

  FEBS letters 20060807

• Chiral mutagenesis of insulin. Contribution of the B20-B23 beta-turn to activity and stability.

  The Journal of biological chemistry 20060804

• Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning.

  The Journal of biological chemistry 20060804

• Aquaporin subfamily with unusual NPA boxes.

  Biochimica et biophysica acta 20060801

• Biocompatibility of elastin-like polymer poly(VPAVG) microparticles: in vitro and in vivo studies.

  Journal of biomedical materials research. Part A 20060801

• Multiple pathways in conformational transitions of the alanine dipeptide: an application of dynamic importance sampling.

  Journal of computational chemistry 20060801

• Time course of acylcarnitine elevation in neonatal intrahepatic cholestasis caused by citrin deficiency.

  Journal of inherited metabolic disease 20060801

• Newborn screening may fail to identify intermediate forms of maple syrup urine disease.

  Journal of inherited metabolic disease 20060801

• Meso-diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD1.

  Journal of immunology (Baltimore, Md. : 1950) 20060801

• The interaction of Fusarium solani pisi cutinase with long chain spin label esters.

  Biochemistry 20060801

• Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060801

• Determination and modeling of peptide pKa by capillary zone electrophoresis.

  Analytical chemistry 20060801

• Definition of Systematic, Approximately Separable, and Modular Internal Coordinates (SASMIC) for macromolecular simulation.

  Journal of computational chemistry 20060730

• Modulation of MthK potassium channel activity at the intracellular entrance to the pore.

  The Journal of biological chemistry 20060728

• Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin.

  Journal of medicinal chemistry 20060727

• Folding of an Ala-Ala-Ala tripeptide into a beta-turn via hydrophobic encapsulation.

  Journal of the American Chemical Society 20060726

• Synthesis of polyhydroxy amino acids based on D- and L-alanine from D-glycero-D-gulo-heptono-1,4-lactone.

  Carbohydrate research 20060724

• Mutational analysis of the p53 core domain L1 loop.

  The Journal of biological chemistry 20060721

• Metabolic changes in glucose transporter-deficient Leishmania mexicana and parasite virulence.

  The Journal of biological chemistry 20060721

• Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060720

• Ab initio molecular dynamics of protonated dialanine and comparison to infrared multiphoton dissociation experiments.

  The journal of physical chemistry. A 20060720

• Lipid solvation effects contribute to the affinity of Gly-xxx-Gly motif-mediated helix-helix interactions.

  Biochemistry 20060718

• The periplasmic domains of Escherichia coli HflKC oligomerize through right-handed coiled-coil interactions.

  Biochemistry 20060718

• Rational design of peptide inhibitors of the sarcoplasmic reticulum calcium pump.

  Biochemistry 20060718

• Radical scavenging activities of alpha-alanine C60 adduct.

  Bioorganic & medicinal chemistry letters 20060715

• Single-step enantioselective amino acid flux analysis by capillary electrophoresis using on-line sample preconcentration with chemical derivatization.

  Analytical biochemistry 20060715

• Sumoylation of Daxx regulates IFN-induced growth suppression of B lymphocytes and the hormone receptor-mediated transactivation.

  Journal of immunology (Baltimore, Md. : 1950) 20060715

• Characterization of the functional epitope on the urokinase receptor. Complete alanine scanning mutagenesis supplemented by chemical cross-linking.

  The Journal of biological chemistry 20060714

• Microcoil high-resolution magic angle spinning NMR spectroscopy.

  Journal of the American Chemical Society 20060712

• Secretin receptor oligomers form intracellularly during maturation through receptor core domains.

  Biochemistry 20060711

• Asp-196-->Ala mutant of Leuconostoc mesenteroides sucrose phosphorylase exhibits altered stereochemical course and kinetic mechanism of glucosyl transfer to and from phosphate.

  FEBS letters 20060710

• Total synthesis and biological evaluation of neodysiherbaine A and analogues.

  The Journal of organic chemistry 20060707

• Is there a folate-related gene-environment interaction in the etiology of childhood acute lymphoblastic leukemia?

  International journal of cancer 20060701

• Functional role of catalytic triad and oxyanion hole-forming residues on enzyme activity of Escherichia coli thioesterase I/protease I/phospholipase L1.

  The Biochemical journal 20060701

• Alanine check points in HNN and HN(C)N spectra.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20060701

• Long stretches of sequential and identical serine or alanine codons are compatible with an efficient full-length protein expression in Escherichia coli.

  Protein expression and purification 20060701

• Podospora anserina target of rapamycin.

  Current genetics 20060701

• 3-hydroxypyridazine 1-oxides as carboxylate bioisosteres: a new series of subtype-selective AMPA receptor agonists.

  Neuropharmacology 20060701

• Exploring the limits of polarization transfer efficiency in homonuclear three spin systems.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20060701

• Folding of Desulfovibrio desulfuricans flavodoxin is accelerated by cofactor fly-casting.

  Archives of biochemistry and biophysics 20060701

• Phosphorylation of S955 at the protein kinase A consensus promotes maturation of the alpha subunit of the colonic H+,K+ -ATPase.

  Journal of the American Society of Nephrology : JASN 20060701

• Characterization of the lipopolysaccharide and beta-glucan of the fish pathogen Francisella victoria.

  The FEBS journal 20060701

• IK682, a tight binding inhibitor of TACE.

  Archives of biochemistry and biophysics 20060701

• Phosphorylation and 14-3-3 binding of Arabidopsis trehalose-phosphate synthase 5 in response to 2-deoxyglucose.

  The Plant journal : for cell and molecular biology 20060701

• A lesson in efficient killing from two-component lantibiotics.

  Molecular microbiology 20060701

• Roles of the human Rad51 L1 and L2 loops in DNA binding.

  The FEBS journal 20060701

• Shifts in microbial community functions and nitrifying communities as a result of combined application of copper and mefenoxam.

  FEMS microbiology letters 20060701

• Aspartic acid 214 in Citrobacter freundii tyrosine phenol-lyase ensures sufficient C--H-acidity of the external aldimine intermediate and proper orientation of the cofactor at the active site.

  Biochimica et biophysica acta 20060701

• Association between Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma 2 and myocardial infarction in the Chinese Han population.

  Clinical cardiology 20060701

• Osteoporosis associated with gyrate atrophy: a case report.

  Documenta ophthalmologica. Advances in ophthalmology 20060701

• [The molecular mechanism of Notch-induced transformation and the therapeutic potential of its inhibitor].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20060701

• Antitumor and antimetastatic effects of betulonic acid amides in mice with transplantable lewis carcinoma.

  Bulletin of experimental biology and medicine 20060701

• Contributions of phenylalanine 335 to ligand recognition by human surfactant protein D: ring interactions with SP-D ligands.

  The Journal of biological chemistry 20060630

• Transition state stabilization and alpha-amino carbon acidity in alanine racemase.

  Journal of the American Chemical Society 20060628

• A genetically encoded fluorescent amino acid.

  Proceedings of the National Academy of Sciences of the United States of America 20060627

• Stereoselective synthesis of orthogonally protected alpha-methylnorlanthionine.

  Organic letters 20060622

• Mutagenesis and molecular modeling reveal the importance of the 5-HT3 receptor F-loop.

  The Journal of biological chemistry 20060616

• NMR and alanine scan studies of glucose-dependent insulinotropic polypeptide in water.

  The Journal of biological chemistry 20060616

• Characterization of a membrane protein folding motif, the Ser zipper, using designed peptides.

  Journal of molecular biology 20060616

• CDKN2A common variant and multi-organ cancer risk--a population-based study.

  International journal of cancer 20060615

• In vivo biodegradability and biocompatibility evaluation of novel alanine ester based polyphosphazenes in a rat model.

  Journal of biomedical materials research. Part A 20060615

• Protection of renal tubular cells against the cytotoxicity of cadmium by glycine.

  Toxicology 20060615

• The double lysine motif of tapasin is a retrieval signal for retention of unstable MHC class I molecules in the endoplasmic reticulum.

  Journal of immunology (Baltimore, Md. : 1950) 20060615

• Structure of a complex of Thermoactinomyces vulgaris R-47 alpha-amylase 2 with maltohexaose demonstrates the important role of aromatic residues at the reducing end of the substrate binding cleft.

  Carbohydrate research 20060612

• Unraveling the importance of protein-protein interaction: application of a computational alanine-scanning mutagenesis to the study of the IgG1 streptococcal protein G (C2 fragment) complex.

  The journal of physical chemistry. B 20060608

• Ribosomal synthesis of dehydroalanine-containing peptides.

  Journal of the American Chemical Society 20060607

• Evaluation of efficiency of reference potential spatial warping algorithm in conformational sampling of peptides.

  The Journal of chemical physics 20060607

• Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice.

  Neurobiology of aging 20060601

• Efficient spin-spin scalar coupling mediated C-13 homonuclear polarization transfer in biological solids without proton decoupling.

  Solid state nuclear magnetic resonance 20060601

• Carbohydrate metabolism during prolonged exercise and recovery: interactions between pyruvate dehydrogenase, fatty acids, and amino acids.

  Journal of applied physiology (Bethesda, Md. : 1985) 20060601

• Glucose and leucine kinetics in idiopathic ketotic hypoglycaemia.

  Archives of disease in childhood 20060601

• Impact of the gliotoxin L-serine-O-sulphate on cellular metabolism in cultured rat astrocytes.

  Neurochemistry international 20060601

• Polarised Raman and infrared spectral analysis of L-alanine oxalate (C5H9NO6)--a non-linear optical single crystal.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060601

• Orientation of TOAC amino-acid spin labels in alpha-helices and beta-strands.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20060601

• Accelerated hepatic glycerol synthesis in rainbow smelt (Osmerus mordax) is fuelled directly by glucose and alanine: a 1H and 13C nuclear magnetic resonance study.

  Journal of experimental zoology. Part A, Comparative experimental biology 20060601

• Reducing CDK4/6-p16(INK4a) interface. Computational alanine scanning of a peptide bound to CDK6 protein.

  Proteins 20060601

• ARTIST: an activated method in internal coordinate space for sampling protein energy landscapes.

  Proteins 20060601

• Effective dipolar couplings determined by dipolar dephasing of double-quantum coherences.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20060601

• Suppression and regression of choroidal neovascularization by systemic administration of an alpha5beta1 integrin antagonist.

  Molecular pharmacology 20060601

• Determination of binding site residues responsible for the subunit selectivity of novel marine-derived compounds on kainate receptors.

  Molecular pharmacology 20060601

• Detailed microscopic study of the full zipA:FtsZ interface.

  Proteins 20060601

• Comments on 'Association between Ala-9Val polymorphism of MnSOD gene and schizophrenia' by O. Akyol et al. Progress in Neuropsychopharmacology and Biological Psychiatry 29, 2005, 123-131.

  Progress in neuro-psychopharmacology & biological psychiatry 20060601

• Residues in two homology blocks on the amino side of the tRNase Z His domain contribute unexpectedly to pre-tRNA 3' end processing.

  RNA (New York, N.Y.) 20060601

• Conformational structure, dynamics, and solvation energies of small alanine peptides in water and carbon tetrachloride.

  Journal of pharmaceutical sciences 20060601

• CD24 Ala/Val polymorphism and multiple sclerosis.

  Journal of neuroimmunology 20060601

• Association study with 33 single-nucleotide polymorphisms in 11 candidate genes for hypertension in Chinese.

  Hypertension (Dallas, Tex. : 1979) 20060601

• Reaction of cytidine nucleotides with cyanoacetylene: support for the intermediacy of nucleoside-2',3'-cyclic phosphates in the prebiotic synthesis of RNA.

  Chembiochem : a European journal of chemical biology 20060601

• Syndapin I is the phosphorylation-regulated dynamin I partner in synaptic vesicle endocytosis.

  Nature neuroscience 20060601

• Glu257 in GroEL is a sensor involved in coupling polypeptide substrate binding to stimulation of ATP hydrolysis.

  Protein science : a publication of the Protein Society 20060601

• Parsing ketotic hypoglycaemia.

  Archives of disease in childhood 20060601

• Role of APP phosphorylation in FE65-dependent gene transactivation mediated by AICD.

  Genes to cells : devoted to molecular & cellular mechanisms 20060601

• Replacement of alanine with asparagic acid at position 203 in human steroidogenic acute regulatory protein impairs the ability to enhance steroidogenesis in vitro.

  Endocrine journal 20060601

• Inhibition of fructose 1,6-bisphosphatase reduces excessive endogenous glucose production and attenuates hyperglycemia in Zucker diabetic fatty rats.

  Diabetes 20060601

• Evidence for asexual genetic recombination in sunflower downy mildew, Plasmopara halstedii.

  Mycological research 20060601

• OPC-12759 increases proliferation of cultured rat conjunctival goblet cells.

  Cornea 20060601

• Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma gene in women with polycystic ovary syndrome.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20060601

• Ala-504 is a determinant of substrate binding affinity in the mouse Na(+)/dicarboxylate cotransporter.

  Biochimica et biophysica acta 20060601

• Investigation of resistance mechanisms to fipronil in diamondback moth (Lepidoptera: Plutellidae).

  Journal of economic entomology 20060601

• Ambroxol for the prevention of acute upper respiratory disease.

  Clinical and experimental medicine 20060601

• Effect of vitamin B6 deficiency on glyoxylate metabolism in rats with or without glyoxylate overload.

  Biomedical research (Tokyo, Japan) 20060601

• A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth.

  The Journal of biological chemistry 20060526

• Identification of the key residues responsible for the assembly of selenodeiodinases.

  The Journal of biological chemistry 20060526

• Substrate specificity of archaeon Sulfolobus tokodaii biotin protein ligase.

  Biochemical and biophysical research communications 20060526

• A highly stereocontrolled total synthesis of (-)-neodysiherbaine A.

  The Journal of organic chemistry 20060526

• Dopamine uptake and cocaine binding mechanisms: the involvement of charged amino acids from the transmembrane domains of the human dopamine transporter.

  European journal of pharmacology 20060524

• Mutations in PRP43 that uncouple RNA-dependent NTPase activity and pre-mRNA splicing function.

  Biochemistry 20060523

• A line integral reaction path approximation for large systems via nonlinear constrained optimization: application to alanine dipeptide and the beta hairpin of protein G.

  The Journal of chemical physics 20060521

• Orbital signatures of methyl in L-alanine.

  The journal of physical chemistry. B 20060518

• The link between sequence and conformation in protein structures appears to be stereochemically established.

  The journal of physical chemistry. B 20060511

• Differential contributions of motilin receptor extracellular domains for peptide and non-peptidyl agonist binding and activity.

  The Journal of biological chemistry 20060505

• Crystal structure and site 1 binding energetics of human placental lactogen.

  Journal of molecular biology 20060505

• RAP uses a histidine switch to regulate its interaction with LRP in the ER and Golgi.

  Molecular cell 20060505

• Differentiating a ligand's chemical requirements for allosteric interactions from those for protein binding. Phenylalanine inhibition of pyruvate kinase.

  Biochemistry 20060502

• Construction, expression, and purification of HIV-TAT-survivin (T34A) mutant: a pro-apoptosis protein in Escherichia coli.

  Protein expression and purification 20060501

• Large-scale preparation of biologically active mouse and rat leptins and their L39A/D40A/F41A muteins which act as potent antagonists.

  Protein expression and purification 20060501

• PII structure in the model peptides for unfolded proteins: studies on ubiquitin fragments and several alanine-rich peptides containing QQQ, SSS, FFF, and VVV.

  Proteins 20060501

• Posttranslational modifications of Bcl2 family members--a potential therapeutic target for human malignancy.

  Frontiers in bioscience : a journal and virtual library 20060501

• Novel application of the 'doubly labeled' water method: measuring CO2 production and the tissue-specific dynamics of lipid and protein in vivo.

  American journal of physiology. Endocrinology and metabolism 20060501

• Absence of convulsive liability of doripenem, a new carbapenem antibiotic, in comparison with beta-lactam antibiotics.

  Toxicology 20060501

• Alanine racemase of alfalfa seedlings (Medicago sativa L.): first evidence for the presence of an amino acid racemase in plants.

  Phytochemistry 20060501

• Monocyte and macrophage activation by lipoteichoic Acid is independent of alanine and is potentiated by hemoglobin.

  Journal of immunology (Baltimore, Md. : 1950) 20060501

• Structure of euhalothece-362, a novel red-shifted mycosporine-like amino acid, from a halophilic cyanobacterium (Euhalothece sp.).

  FEMS microbiology letters 20060501

• Statins are associated with lower risk of gastrointestinal bleeding in patients with unstable coronary syndromes: analysis of the Orbofiban in Patients with Unstable coronary Syndromes-Thrombolysis In Myocardial Infarction 16 (OPUS-TIMI 16) trial.

  American heart journal 20060501

• Role of genetic polymorphism peroxisome proliferator-activated receptor-gamma2 Pro12Ala on ethnic susceptibility to diabetes in South-Asian and Caucasian subjects: Evidence for heterogeneity.

  Diabetes care 20060501

• The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on glucose/insulin metabolism interact with prenatal exposure to famine.

  Diabetes care 20060501

• Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion.

  The Journal of endocrinology 20060501

• Identification of a new allele, HLA-DRB5*0113, through three different molecular biology techniques.

  Tissue antigens 20060501

• Conformation of the backbone in unfolded proteins.

  Chemical reviews 20060501

• Purification and characterization of a Cl- -activated aminopeptidase from bovine skeletal muscle.

  Bioscience, biotechnology, and biochemistry 20060501

• Hepatoprotective effects of whey protein on D-galactosamine-induced hepatitis and liver fibrosis in rats.

  Bioscience, biotechnology, and biochemistry 20060501

• Cyanide metabolism in higher plants: cyanoalanine hydratase is a NIT4 homolog.

  Plant molecular biology 20060501

• The N-terminus of Himar1 mariner transposase mediates multiple activities during transposition.

  Genetica 20060501

• Inhibition of histidine ammonia lyase by heteroaryl-alanines and acrylates.

  Chemistry & biodiversity 20060501

• In vitro and in vivo effect of parathyroid hormone analogue (1-14) containing -amino-iso-butyric acid residue (Aib)1,3.

  Yonsei medical journal 20060430

• Mutational analysis of membrane and soluble forms of human MD-2.

  The Journal of biological chemistry 20060428

• Structures of Staphylococcus aureus cell-wall complexes with vancomycin, eremomycin, and chloroeremomycin derivatives by 13C{19F} and 15N{19F} rotational-echo double resonance.

  Biochemistry 20060425

• Ggamma13 interacts with PDZ domain-containing proteins.

  The Journal of biological chemistry 20060421

• Fumarate reductase and succinate oxidase activity of Escherichia coli complex II homologs are perturbed differently by mutation of the flavin binding domain.

  The Journal of biological chemistry 20060421

• Structure-activity relationship studies on N3-substituted willardiine derivatives acting as AMPA or kainate receptor antagonists.

  Journal of medicinal chemistry 20060420

• Glycine-alanine repeats impair proper substrate unfolding by the proteasome.

  The EMBO journal 20060419

• Structural perturbations in the Ala --> Val polymorphism of methylenetetrahydrofolate reductase: how binding of folates may protect against inactivation.

  Biochemistry 20060418

• The molecular basis for differential dioxin sensitivity in birds: role of the aryl hydrocarbon receptor.

  Proceedings of the National Academy of Sciences of the United States of America 20060418

• Design, synthesis, and biological evaluation of a scaffold for iGluR ligands based on the structure of (-)-dysiherbaine.

  Bioorganic & medicinal chemistry letters 20060415

• A comparative theoretical study of dipeptide solvation in water.

  Journal of computational chemistry 20060415

• Clinical and biochemical characteristics in patients with a high mutant load of the mitochondrial T8993G/C mutations.

  American journal of medical genetics. Part A 20060415

• Effect of D-alanylation of (lipo)teichoic acids of Staphylococcus aureus on host secretory phospholipase A2 action before and after phagocytosis by human neutrophils.

  Journal of immunology (Baltimore, Md. : 1950) 20060415

• Transport of the IgE receptor alpha-chain is controlled by a multicomponent intracellular retention signal.

  The Journal of biological chemistry 20060414

• Conformational flexibility of L-alanine zwitterion determines shapes of Raman and Raman optical activity spectral bands.

  The journal of physical chemistry. A 20060413

• A non-cleavable UmuD variant that acts as a UmuD' mimic.

  The Journal of biological chemistry 20060407

• Alanine scanning mutagenesis of Abeta(1-40) amyloid fibril stability.

  Journal of molecular biology 20060407

• Comparative assessment of two indices of drug induced permeability changes in the perfused rat intestine.

  International journal of pharmaceutics 20060407

• Conformational and quantitative characterization of oritavancin-peptidoglycan complexes in whole cells of Staphylococcus aureus by in vivo 13C and 15N labeling.

  Journal of molecular biology 20060407

• Suicide inhibition of alpha-oxamine synthases: structures of the covalent adducts of 8-amino-7-oxononanoate synthase with trifluoroalanine.

  Organic & biomolecular chemistry 20060407

• Aggregation of polyalanine in a hydrophobic environment.

  The Journal of chemical physics 20060407

• Discovery and preclinical studies of (R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5- methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan- 2-ol (BMS-540215), an in vivo active potent VEGFR-2 inhibitor.

  Journal of medicinal chemistry 20060406

• Conformational analysis of XA and AX dipeptides in water by electronic circular dichroism and 1H NMR spectroscopy.

  The journal of physical chemistry. B 20060406

• Putative aggregation initiation sites in prion protein.

  FEBS letters 20060403

• Formation of peptides in the dry state.

  Peptides 20060401

• Structure-activity relationship of ETH during ecdysis in the tobacco hornworm, Manduca sexta.

  Peptides 20060401

• A novel small reporter gene and HIV-1 fitness assay.

  Journal of virological methods 20060401

• Optimization of dansyl derivatization and chromatographic conditions in the determination of neuroactive amino acids of biological samples.

  Clinica chimica acta; international journal of clinical chemistry 20060401

• Molecular dynamics studies of the archaeal translocon.

  Biophysical journal 20060401

• Molecular and biochemical characterization of a serine racemase from Arabidopsis thaliana.

  Phytochemistry 20060401

• Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagon, lactate and TNF-alpha in patients with HIV-lipodystrophy.

  HIV medicine 20060401

• Solvation of the folding-transition state in Pseudomonas aeruginosa azurin is modulated by metal: Solvation of azurin's folding nucleus.

  Protein science : a publication of the Protein Society 20060401

• Characterization and genetic distance analysis of isolates of Peronosclerospora sorghi using AFLP fingerprinting.

  Mycological research 20060401

• Trafficking in persulfides: delivering sulfur in biosynthetic pathways.

  Nature chemical biology 20060401

• Effects of amino acid on morphological development and nucleus formation of arachidonic acid-producing filamentous micro-organism, Mortierella alpina.

  Journal of applied microbiology 20060401

• Inhibition of Lon-dependent degradation of the Escherichia coli transcription activator SoxS by interaction with 'soxbox' DNA or RNA polymerase.

  Molecular microbiology 20060401

• The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: the Data From an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) study.

  Diabetes 20060401

• Syntheses of model compounds related to an antigenic epitope in pectic polysaccharides from Bupleurum falcatum L. (II).

  Chemical & pharmaceutical bulletin 20060401

• Glutamate levels in aqueous humor of patients with retinal artery occlusion.

  Retina (Philadelphia, Pa.) 20060401

• A91V perforin variation in healthy subjects and FHLH patients.

  International journal of immunogenetics 20060401

• Differential effects of alphaCaMKII mutation on hippocampal learning and changes in intrinsic neuronal excitability.

  The European journal of neuroscience 20060401

• Biochemical characterization of Drosophila gamma-glutamyl carboxylase and its role in fly development.

  Insect molecular biology 20060401

• Structural analysis of a mutant of the HIV-1 integrase zinc finger domain that forms a single conformation.

  Journal of biochemistry 20060401

• Cardiolipin enrichment in spore membranes and its involvement in germination of Bacillus subtilis Marburg.

  Genes & genetic systems 20060401

• Novel N-acyl dehydroalanine derivatives as antioxidants: studies on rat liver lipid peroxidation levels and DPPH free radical scavenging activity.

  Journal of enzyme inhibition and medicinal chemistry 20060401

• Leucine motif-dependent tyrosine autophosphorylation of type III receptor tyrosine kinases.

  The Journal of biological chemistry 20060331

• Kinetic computational alanine scanning: application to p53 oligomerization.

  Journal of molecular biology 20060331

• Scanning mutagenesis studies reveal multiple distinct regions within the human protein kinase C alpha regulatory domain important for phorbol ester-dependent activation of the enzyme.

  Journal of molecular biology 20060331

• Sequence requirements for Lon-dependent degradation of the Escherichia coli transcription activator SoxS: identification of the SoxS residues critical to proteolysis and specific inhibition of in vitro degradation by a peptide comprised of the N-terminal 21 amino acid residues.

  Journal of molecular biology 20060331

• Activity of human dihydrolipoamide dehydrogenase is largely reduced by mutation at isoleucine-51 to alanine.

  Journal of biochemistry and molecular biology 20060331

• Angiotensin converting enzyme inhibitory activity of amino acid esters of carbohydrates.

  International journal of biological macromolecules 20060330

• PAX6 missense mutations associated in patients with optic nerve malformation.

  Molecular vision 20060330

• Interactions involved in the realignment of membrane-associated helices. An investigation using oriented solid-state NMR and attenuated total reflection Fourier transform infrared spectroscopies.

  The Journal of biological chemistry 20060324

• Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation.

  The Journal of biological chemistry 20060324

• Phosphorylation of the hinge domain of the nuclear hormone receptor LRH-1 stimulates transactivation.

  The Journal of biological chemistry 20060324

• Synthesis, pharmacological evaluation, and molecular modeling studies of novel peptidic CAAX analogues as farnesyl-protein-transferase inhibitors.

  Journal of medicinal chemistry 20060323

• Time dependent density functional theory modeling of chiroptical properties of small amino acids in solution.

  The journal of physical chemistry. A 20060323

• The shape of beta-alanine.

  Journal of the American Chemical Society 20060322

• Fluorescence energy transfer studies of human deoxycytidine kinase: role of cysteine 185 in the conformational changes that occur upon substrate binding.

  Biochemistry 20060321

• The interaction of heteroaryl-acrylates and alanines with phenylalanine ammonia-lyase from parsley.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060320

• [Interactions between the MTHFR C677T and MTHFR A1298C mutations in ischaemic stroke].

  Ideggyogyaszati szemle 20060320

• Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2.

  The Journal of biological chemistry 20060317

• Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation.

  The Journal of biological chemistry 20060317

• A nuclear transport signal in mammalian target of rapamycin is critical for its cytoplasmic signaling to S6 kinase 1.

  The Journal of biological chemistry 20060317

• Modulation of chaperone function and cochaperone interaction by novobiocin in the C-terminal domain of Hsp90: evidence that coumarin antibiotics disrupt Hsp90 dimerization.

  The Journal of biological chemistry 20060317

• Targeted in vivo mutations of the AMPA receptor subunit GluR2 and its interacting protein PICK1 eliminate cerebellar long-term depression.

  Neuron 20060316

• The role of backbone stability near Ala44 in the high reduction potential class of rubredoxins.

  Proteins 20060315

• Epitope enhancement of a CD4 HIV epitope toward the development of the next generation HIV vaccine.

  Journal of immunology (Baltimore, Md. : 1950) 20060315

• Design of a hyperstable protein by rational consideration of unfolded state interactions.

  Journal of the American Chemical Society 20060315

• Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060315

• Glycogen synthase kinase 3beta phosphorylates Alzheimer's disease-specific Ser396 of microtubule-associated protein tau by a sequential mechanism.

  Biochemistry 20060314

• Evidence for disorder in L-alanine lattice detected by Pulsed-EPR spectroscopy at cryogenic temperatures.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060313

• Analyses of the EPR responses of sucrose and L-alpha-alanine radicals induced by C, Ne, and Ar ion irradiations.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060313

• Solid state 'self-calibrated' EPR-dosimeters-advantageous and shortcomings.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060313

• Toxic actions of dinoseb in medaka (Oryzias latipes) embryos as determined by in vivo 31P NMR, HPLC-UV and 1H NMR metabolomics.

  Aquatic toxicology (Amsterdam, Netherlands) 20060310

• Phosphorylation of serine 526 is required for MEKK3 activity, and association with 14-3-3 blocks dephosphorylation.

  The Journal of biological chemistry 20060310

• Novel oral formulation safely improving intestinal absorption of poorly absorbable drugs: utilization of polyamines and bile acids.

  Journal of controlled release : official journal of the Controlled Release Society 20060310

• Disulfiram irreversibly aggregates betaine aldehyde dehydrogenase--a potential target for antimicrobial agents against Pseudomonas aeruginosa.

  Biochemical and biophysical research communications 20060310

• Lipolanthionine peptides act as inhibitors of TLR2-mediated IL-8 secretion. Synthesis and structure-activity relationships.

  Journal of medicinal chemistry 20060309

• Total synthesis and evaluation of [Psi[CH2NH]Tpg4]vancomycin aglycon: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding.

  Journal of the American Chemical Society 20060308

• Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060308

• Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators.

  Brain research 20060303

• A novel route to dipeptides via noncondensation of amino acids: 2-aminoperfluoropropene as a synthon for trifluoroalanine dipeptides.

  Organic letters 20060302

• Cell-surface targeting of alpha2-adrenergic receptors -- inhibition by a transport deficient mutant through dimerization.

  Cellular signalling 20060301

• The inhibitory effects of rebamipide on cigarette smoke-induced airway mucin production.

  Respiratory medicine 20060301

• Alanine scanning mutagenesis of the chemokine receptor CCR3 reveals distinct extracellular residues involved in recognition of the eotaxin family of chemokines.

  Molecular immunology 20060301

• Triple-quantum correlation NMR experiments in solids using J-couplings.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20060301

• Alanine substitution of conserved residues in the cytoplasmic tail of herpes simplex virus gB can enhance or abolish cell fusion activity and viral entry.

  Virology 20060301

• Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors.

  Genes & development 20060301

• The occurrence of free D-alanine and an alanine racemase activity in Leishmania amazonensis.

  FEMS microbiology letters 20060301

• Free amino acids in hearts of pediatric patients with congenital heart disease: the effects of cyanosis, age, and pathology.

  The Annals of thoracic surgery 20060301

• Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes.

  Traffic (Copenhagen, Denmark) 20060301

• Association of cryptorchidism with Gly146Ala polymorphism in the gene for steroidogenic factor-1.

  Fertility and sterility 20060301

• Monitoring the kinetics of Bacillus subtilis endospore germination via surface-enhanced Raman scattering spectroscopy.

  Analytical chemistry 20060301

• Effect of side group chemistry on the properties of biodegradable L-alanine cosubstituted polyphosphazenes.

  Biomacromolecules 20060301

• A role for transmembrane domains V and VI in ligand binding and maturation of the angiotensin II AT1 receptor.

  Biological chemistry 20060301

• A case of biopsy-proven leptomeningeal amyloidosis and intravenous Ig-responsive polyneuropathy associated with the Ala25Thr transthyretin gene mutation.

  Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20060301

• Plasma level of a 5-fluorouracil metabolite, fluoro-beta-alanine correlates with dihydropyrimidine dehydrogenase activity of peripheral blood mononuclear cells in 5-fluorouracil treated patients.

  Journal of experimental & clinical cancer research : CR 20060301

• Enzyme dynamics along the reaction coordinate: critical role of a conserved residue.

  Biochemistry 20060227

• Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease.

  Neurology 20060227

• The homotrimeric structure of HtrA2 is indispensable for executing its serine protease activity.

  Experimental & molecular medicine 20060227

• A carboxyl-terminal determinant of the neuronal glutamate transporter, EAAC1, is required for platelet-derived growth factor-dependent trafficking.

  The Journal of biological chemistry 20060224

• Alanine scanning of MS2 coat protein reveals protein-phosphate contacts involved in thermodynamic hot spots.

  Journal of molecular biology 20060224

• FGFR3 dimer stabilization due to a single amino acid pathogenic mutation.

  Journal of molecular biology 20060224

• Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides.

  Journal of medicinal chemistry 20060223

• Vitamin D receptor: ligand recognition and allosteric network.

  Journal of medicinal chemistry 20060223

• The L561A substitution in the nascent base-pair binding pocket of RB69 DNA polymerase reduces base discrimination.

  Biochemistry 20060221

• First-principles studies of chiral step reconstructions of Cu(100) by adsorbed glycine and alanine.

  The Journal of chemical physics 20060221

• The conserved Ala37 in the ERF/AP2 domain is essential for binding with the DRE element and the GCC box.

  FEBS letters 20060220

• Single-point mutations of hepatitis C virus NS3 that impair p53 interaction and anti-apoptotic activity of NS3.

  Biochemical and biophysical research communications 20060217

• Selective adsorption and reactivity of dipeptide stereoisomers in clay mineral suspension.

  Journal of colloid and interface science 20060215

• Mutation analysis of the ATM gene in two Chinese patients with ataxia telangiectasia.

  Journal of the neurological sciences 20060215

• F200A substitution in the third transmembrane helix of human cannabinoid CB1 receptor converts AM2233 from receptor agonist to inverse agonist.

  European journal of pharmacology 20060215

• Alcohol potently modulates climbing fiber-->Purkinje neuron synapses: role of metabotropic glutamate receptors.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060215

• Engineering artificially split inteins for applications in protein chemistry: biochemical characterization of the split Ssp DnaB intein and comparison to the split Sce VMA intein.

  Biochemistry 20060214

• Solution structure of the first intracellular loop of prostacyclin receptor and implication of its interaction with the C-terminal segment of G alpha s protein.

  Biochemistry 20060214

• Identification of coagulation factor VIII A2 domain residues forming the binding epitope for low-density lipoprotein receptor-related protein.

  Biochemistry 20060214

• Different residues mediate recognition of 1-O-oleyllysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor gamma.

  The Journal of biological chemistry 20060210

• Akt kinase phosphorylation of inositol 1,4,5-trisphosphate receptors.

  The Journal of biological chemistry 20060210

• The 'GyrA-box' is required for the ability of DNA gyrase to wrap DNA and catalyze the supercoiling reaction.

  The Journal of biological chemistry 20060210

• Substrate specificity of an active dinuclear Zn(II) catalyst for cleavage of RNA analogues and a dinucleoside.

  Journal of the American Chemical Society 20060208

• A preliminary study of the interaction of glass-ionomer dental cements with amino acids.

  Dental materials : official publication of the Academy of Dental Materials 20060201

• D-alanine added to antipsychotics for the treatment of schizophrenia.

  Biological psychiatry 20060201

• Improved bioavailability of the mGlu2/3 receptor agonist LY354740 using a prodrug strategy: in vivo pharmacology of LY544344.

  The Journal of pharmacology and experimental therapeutics 20060201

• EFA (9-beta-D-erythrofuranosyladenine) is an effective salvage agent for methylthioadenosine phosphorylase-selective therapy of T-cell acute lymphoblastic leukemia with L-alanosine.

  Blood 20060201

• Conversion of a porin-like peptide channel into a gramicidin-like channel by glycine to D-alanine substitutions.

  Biophysical journal 20060201

• Sensitivity and resolution in proton solid-state NMR at intermediate deuteration levels: quantitative linewidth characterization and applications to correlation spectroscopy.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20060201

• SimFold energy function for de novo protein structure prediction: consensus with Rosetta.

  Proteins 20060201

• Molecular and synaptic changes in the hippocampus underlying superior spatial abilities in pre-symptomatic G93A+/+ mice overexpressing the human Cu/Zn superoxide dismutase (Gly93 --> ALA) mutation.

  Experimental neurology 20060201

• Gln49 and Ser174 residues play critical roles in determining the catalytic efficiencies of plant glutamine synthetase.

  Plant & cell physiology 20060201

• Alanine substitution and deletion analogues of Manduca sexta allatostatin: structure-activity relationship on the spontaneous contractions of the foregut of larval Lacanobia oleracea.

  Journal of insect physiology 20060201

• Functional characterization of sequence motifs in the transit peptide of Arabidopsis small subunit of rubisco.

  Plant physiology 20060201

• Kinetic characterization and ligand binding studies of His351 mutants of Bacillus anthracis adenylate cyclase.

  Archives of biochemistry and biophysics 20060201

• Host-mediated phosphorylation of type III effector AvrPto promotes Pseudomonas virulence and avirulence in tomato.

  The Plant cell 20060201

• The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes.

  Journal of structural biology 20060201

• Intestinal adaptation to diet in the young domestic and wild turkey (Meleagris gallopavo).

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20060201

• Morphogenetic surfactants and their role in the formation of aerial hyphae in Streptomyces coelicolor.

  Molecular microbiology 20060201

• An alanine in segment 3 of domain III (IIIS3) of the cockroach sodium channel contributes to the low pyrethroid sensitivity of an alternative splice variant.

  Insect biochemistry and molecular biology 20060201

• Mild-onset presentation of Canavan's disease associated with novel G212A point mutation in aspartoacylase gene.

  Annals of neurology 20060201

• Risk factors for stroke after acute coronary syndromes in the Orbofiban in Patients with Unstable Coronary Syndromes--Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study.

  American heart journal 20060201

• Ste20-type kinases: evolutionarily conserved regulators of ion transport and cell volume.

  Physiology (Bethesda, Md.) 20060201

• Metabolic phenotyping of nude and normal (Alpk:ApfCD, C57BL10J) mice.

  Journal of proteome research 20060201

• Optimization of suppository preparation containing sodium laurate and taurine that can safely improve rectal absorption of rebamipide.

  Biological & pharmaceutical bulletin 20060201

• Circadian pharmacology of L-alanosine (SDX-102) in mice.

  Molecular cancer therapeutics 20060201

• Cellular localization and phosphorylation of Hrb1p is independent of Sky1p.

  Biochimica et biophysica acta 20060201

• Analysis of the three dimensional structure of the CXGXC motif in the CMGCC and CAGYC regions of alpha-and beta-subunits of human chorionic gonadotropin: importance of glycine residue (G) in the motif.

  Endocrine journal 20060201

• The effect of L-alanine therapy in a patient with adult onset glycogen storage disease type II.

  Journal of inherited metabolic disease 20060201

• Ab initio study of alanine polypeptide chain twisting.

  Physical review. E, Statistical, nonlinear, and soft matter physics 20060201

• [Temperature-dependent optical activity and birefringence study of D-alanine single crystal].

  Guang pu xue yu guang pu fen xi = Guang pu 20060201

• Monte Carlo simulations of biomolecules: The MC module in CHARMM.

  Journal of computational chemistry 20060130

• Successful treatment of severe pouchitis with rebamipide refractory to antibiotics and corticosteroids: a case report.

  World journal of gastroenterology 20060128

• Paratope determination of the antithrombotic antibody 82D6A3 based on the crystal structure of its complex with the von Willebrand factor A3-domain.

  The Journal of biological chemistry 20060127

• Interacting residues in an activated state of a G protein-coupled receptor.

  The Journal of biological chemistry 20060127

• Role of the solvent glycerol in the Maillard reaction of d-fructose and l-alanine.

  Journal of agricultural and food chemistry 20060125

• Helix-sense controlled polymerization of a single phenyl isocyanide enantiomer leading to diastereomeric helical polyisocyanides with opposite helix-sense and cholesteric liquid crystals with opposite twist-sense.

  Journal of the American Chemical Society 20060125

• Computational design of heterochiral peptides against a helical target.

  Journal of the American Chemical Society 20060125

• The second intracellular loop of the calcitonin gene-related peptide receptor provides molecular determinants for signal transduction and cell surface expression.

  The Journal of biological chemistry 20060120

• T-state active site of aspartate transcarbamylase: crystal structure of the carbamyl phosphate and L-alanosine ligated enzyme.

  Biochemistry 20060117

• Radical intermediates in the catalytic oxidation of hydrocarbons by bacterial and human cytochrome P450 enzymes.

  Biochemistry 20060117

• Modelling the effect of a heat shock and germinant concentration on spore germination of a wild strain of Bacillus cereus.

  International journal of food microbiology 20060115

• Binding efficiency of elongation factor Tu to tRNAs charged with nonnatural fluorescent amino acids.

  Analytical biochemistry 20060115

• Deficiency of disulfide bonds facilitating fibrillogenesis of endostatin.

  The Journal of biological chemistry 20060113

• Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine.

  Biochemistry 20060110

• Influence of secondary reactions on the synthetic efficiency of DHAP-aldolases.

  Biotechnology and bioengineering 20060105

• An alpha-formylglycine building block for fmoc-based solid-phase peptide synthesis.

  Organic letters 20060105

• Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060104

• Persistent arterial hyperammonemia increases the concentration of glutamine and alanine in the brain and correlates with intracranial pressure in patients with fulminant hepatic failure.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060101

• Mechanisms for abnormal postprandial glucose metabolism in type 2 diabetes.

  American journal of physiology. Endocrinology and metabolism 20060101

• Brain oxygen utilization is unchanged by hypoglycemia in normal humans: lactate, alanine, and leucine uptake are not sufficient to offset energy deficit.

  American journal of physiology. Endocrinology and metabolism 20060101

• Hadamard NMR spectroscopy in solids.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20060101

• Critical structure-function determinants within the N-terminal region of pulmonary surfactant protein SP-B.

  Biophysical journal 20060101

• A DOQSY approach for the elucidation of torsion angle distributions in biopolymers: application to silk.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20060101

• Synthesis, characterization, and osteocompatibility evaluation of novel alanine-based polyphosphazenes.

  Journal of biomedical materials research. Part A 20060101

• Mechanism of the phosphatase component of Clostridium thermocellum polynucleotide kinase-phosphatase.

  RNA (New York, N.Y.) 20060101

• Endogenous hydrogen sulfide contributes to the cardioprotection by metabolic inhibition preconditioning in the rat ventricular myocytes.

  Journal of molecular and cellular cardiology 20060101

• Polymorphisms of ADPRT Val762Ala and XRCC1 Arg399Glu and risk of breast cancer in Chinese women: a case control analysis.

  Oncology reports 20060101

• NMDA receptor subunit-dependent modulation by conantokin-G and Ala7-conantokin-G.

  Journal of neurochemistry 20060101

• Fixed metabolic costs for highly variable rates of protein synthesis in sea urchin embryos and larvae.

  The Journal of experimental biology 20060101

• The in vivo effects of the Pro12Ala PPARgamma2 polymorphism on adipose tissue NEFA metabolism: the first use of the Oxford Biobank.

  Diabetologia 20060101

• Active site residues governing substrate selectivity and polyketide chain length in aloesone synthase.

  The FEBS journal 20060101

• Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycosylation, expressed in human embryonic kidney 293T cells.

  The FEBS journal 20060101

• Erythrocyte membrane acetylcholinesterase activity in subjects with MTHFR 677C-->T genotype.

  Clinical chemistry and laboratory medicine 20060101

• Fatty acid alterations in liver peroxisomes from n-3-deficient mice.

  Annals of nutrition & metabolism 20060101

• Mutation of Thr466 in SHP2 abolishes its phosphatase activity, but provides a new substrate-trapping mutant.

  Biochimica et biophysica acta 20060101

• Highly expressed proteins have an increased frequency of alanine in the second amino acid position.

  BMC genomics 20060101

• Deletion and alanine mutation analyses for the formation of active homo- or hetero-dimer complexes of mouse choline kinase-alpha and -beta.

  Biochimica et biophysica acta 20060101

• Short-term fasting, seizure control and brain amino acid metabolism.

  Neurochemistry international 20060101

• Crystallization of a functionally intact Hsc70 chaperone.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060101

• Purification and characterization of l,(l/d)-aminopeptidase from Guinea pig serum.

  Preparative biochemistry & biotechnology 20060101

• High-affinity glutamate transporter GLAST/EAAT1 regulates cell surface expression of glutamine/neutral amino acid transporter ASCT2 in human fetal astrocytes.

  Neurochemistry international 20060101

• [Biological preparations with different mechanism of action for protecting potato against fungal diseases].

  Prikladnaia biokhimiia i mikrobiologiia 20060101

• Conformational properties of N-acetyl-N-methyl-alpha,beta-dehydroalanine N'-methylamide.

  Acta biochimica Polonica 20060101

• [Germination of Bacillus anthracis spores].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20060101

• A novel molecular inactivation determinant of voltage-gated CaV1.2 L-type Ca2+ channel.

  Neuroscience 20060101

• Cytoplasmic domain phosphorylation of heparin-binding EGF-like growth factor.

  Cell structure and function 20060101

• EPR/alanine dosimetry in LDR brachytherapy--a feasibility study.

  Radiation protection dosimetry 20060101

• Combined effects of high doses and temperature on radiation-induced radicals and their relative contributions to EPR signal in gamma-irradiated alanine.

  Radiation protection dosimetry 20060101

• Erythrocyte membrane Na+,K+-ATPase and Mg2+-ATPase activities in subjects with methylenetetrahydrofolate reductase (MTHFR) 677 C-->T genotype and moderate hyperhomocysteinaemia. The role of L-phenylalanine and L-alanine.

  Clinical chemistry and laboratory medicine 20060101

• Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome amongst the Taiwanese population- not correlated with insulin receptor substrate-1 Gly972Arg/Ala513Pro polymorphism.

  BMC medical genetics 20060101

• Different allele-distribution of mthfr 677 C -> T and mthfr -393 C -> a in patients classified according to subtypes of Lesch's typology.

  Alcohol and alcoholism (Oxford, Oxfordshire) 20060101

• Use of commercial alanine and TL dosemeters for dosimetry intercomparisons among Italian radiotherapy centres.

  Radiation protection dosimetry 20060101

• A study of the irradiation temperature coefficient for L-alanine and DL-alanine dosemeters.

  Radiation protection dosimetry 20060101

• The dogfish shark (Squalus acanthias) increases both hepatic and extrahepatic ornithine urea cycle enzyme activities for nitrogen conservation after feeding.

  Physiological and biochemical zoology : PBZ 20060101

• A pilot study to evaluate a new combination therapy for gastric ulcer: Helicobacter pylori eradication therapy followed by gastroprotective treatment with rebamipide.

  Journal of gastroenterology and hepatology 20060101

• [Familial well-differentiated thyroid carcinoma].

  Voprosy onkologii 20060101

• Normal serum alanine concentration differentiates transient neonatal lactic acidemia from an inborn error of energy metabolism.

  Biology of the neonate 20060101

• Peroxisome proliferator-activated receptor-gamma polymorphism, body mass and prostate cancer risk: evidence for gene-environment interaction.

  Oncology 20060101

• Mode of inhibition of HIV-1 Integrase by a C-terminal domain-specific monoclonal antibody.

  Retrovirology 20060101

• Uptake, metabolism and distribution of organic and inorganic nitrogen sources by Pinus sylvestris.

  Journal of experimental botany 20060101

• [Raman scattering study of DL-alanine].

  Guang pu xue yu guang pu fen xi = Guang pu 20060101

• Nuclear magnetic resonance spectroscopy of bovine ovarian follicular fluid at four selected times of the oestrous cycle.

  Reproduction, fertility, and development 20060101

• Ligand recognition by vitamin D receptor: total alanine scanning mutational analysis of the residues lining the ligand binding pocket of vitamin D receptor.

  Current topics in medicinal chemistry 20060101

• Population pharmacokinetic analysis of panipenem/betamipron in patients with various degrees of renal function.

  Chemotherapy 20060101

• Amino acid catabolic pathways of lactic acid bacteria.

  Critical reviews in microbiology 20060101

• Characterization of alanine aminotransferase (AlaAT) multigene family and hypoxic response in young seedlings of the model legume Medicago truncatula.

  Journal of experimental botany 20060101

• The P1812A and P25T BRCA1 and the 5164del4 BRCA2 mutations: occurrence in high-risk non-Ashkenazi Jews.

  Genetic testing 20060101

• Plasmid DNA delivery by D-alanine-deficient Listeria monocytogenes.

  Biotechnology progress 20060101

• Role of mouse hepatitis coronavirus envelope protein transmembrane domain.

  Advances in experimental medicine and biology 20060101

• Contribution of L-alanine dehydrogenase to in vivo persistence and protective efficacy of the BCG vaccine.

  Microbiology and immunology 20060101

• Flight fuel and neuropeptidergic control of fuel mobilisation in the twig wilter, Holopterna alata (Hemiptera, Coreidae).

  Journal of insect physiology 20060101

• Chiral separation of metalaxyl by capillary zone electrophoresis using cyclodextrins.

  Journal of capillary electrophoresis and microchip technology 20060101

• Properties of volume-activated taurine efflux from human breast cancer cells.

  Advances in experimental medicine and biology 20060101

• Development of physical and numerical techniques of Alanine/EPR dosimetry in radiotherapy.

  Radiation protection dosimetry 20060101

• [Seasonal variations of free amino acids the content of body flows in the fresh-water mollusk Lymnaea stagnalis].

  Izvestiia Akademii nauk. Seriia biologicheskaia 20060101

• Oxidative stress involvement and gene expression in indomethacin-induced gastropathy.

  Redox report : communications in free radical research 20060101

• Bioassay of safinamide in biological fluids of humans and various animal species.

  Arzneimittel-Forschung 20060101

• Dehydroalanine-containing peptides: preparation from phenylselenocysteine and utility in convergent ligation strategies.

  Nature protocols 20060101

• Comparison of structure and dynamics of micelle-bound human alpha-synuclein and Parkinson disease variants.

  The Journal of biological chemistry 20051230

• Role of the transmembrane domain of FXYD7 in structural and functional interactions with Na,K-ATPase.

  The Journal of biological chemistry 20051230

• Synergistic effects on escape of a ligand from the closed tryptophan synthase bienzyme complex.

  Biochemistry 20051227

• Exploring the free-energy landscape of a short peptide using an average force.

  The Journal of chemical physics 20051222

• Programming the internal structure and stability of helical pores self-assembled from dendritic dipeptides via the protective groups of the peptide.

  Journal of the American Chemical Society 20051221

• Guanidine derivatives rescue the Arg418Ala mutation of Tritrichomonas foetus IMP dehydrogenase.

  Biochemistry 20051220

• All four putative selectivity filter glycine residues in KtrB are essential for high affinity and selective K+ uptake by the KtrAB system from Vibrio alginolyticus.

  The Journal of biological chemistry 20051216

• Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity.

  The Journal of biological chemistry 20051216

• Differential contribution of troponin I phosphorylation sites to the endothelin-modulated contractile response.

  The Journal of biological chemistry 20051216

• Crystal structure of cone arrestin at 2.3A: evolution of receptor specificity.

  Journal of molecular biology 20051216

• Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity.

  Journal of molecular biology 20051216

• Genetics. Zebrafish researchers hook gene for human skin color.

  Science (New York, N.Y.) 20051216

• SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans.

  Science (New York, N.Y.) 20051216

• Essential role for Pro21 in phospholamban for optimal inhibition of the Ca-ATPase.

  Biochemistry 20051213

• Regulation of the catalytic activity of PTP1B: roles for cell adhesion, tyrosine residue 66, and proline residues 309 and 310.

  Experimental cell research 20051210

• Pseudomonas aeruginosa LD-carboxypeptidase, a serine peptidase with a Ser-His-Glu triad and a nucleophilic elbow.

  The Journal of biological chemistry 20051209

• Phosphorylation by protein kinase a inhibits nuclear import of 5-lipoxygenase.

  The Journal of biological chemistry 20051209

• Mild and chemoselective peptide-bond cleavage of peptides and proteins at azido homoalanine.

  Angewandte Chemie (International ed. in English) 20051209

• Characterization of two new variants of human catechol O-methyltransferase in vitro.

  Cancer letters 20051208

• Growth restriction and the cerebral metabolic response to acute hypoxia of chick embryos in-ovo: a proton magnetic resonance spectroscopy study.

  Brain research. Developmental brain research 20051207

• Energetic characterization of short helical polyalanine peptides in water: analysis of 13C=O chemical shift data.

  Journal of the American Chemical Society 20051207

• Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells.

  Journal of the National Cancer Institute 20051207

• Alanine 101 and alanine 110 of the alpha subunit of Pseudomonas stutzeri OX1 toluene-o-xylene monooxygenase influence the regiospecific oxidation of aromatics.

  Biotechnology and bioengineering 20051205

• Inhibition of in vitro RNA binding and replicase activity by phosphorylation of the p33 replication protein of Cucumber necrosis tombusvirus.

  Virology 20051205

• Structural and thermal characterization of ternary complexes of piroxicam and alanine with transition metals: uranyl binary and ternary complexes of piroxicam. Spectroscopic characterization and properties of metal complexes.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051201

• Topiramate prevents excitotoxic damage in the newborn rodent brain.

  Neurobiology of disease 20051201

• Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation.

  Oncogene 20051201

• A hydrophobic cluster in the center of the third extracellular loop is important for thyrotropin receptor signaling.

  Endocrinology 20051201

• Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract.

  Journal of cancer research and clinical oncology 20051201

• Heteronuclear decoupling interference during symmetry-based homonuclear recoupling in solid-state NMR.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20051201

• A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscle.

  The Journal of physiology 20051201

• Tryptophan at position 104 is involved in transforming light signal into changes of beta-sheet structure for the signaling state in the BLUF domain of AppA.

  Plant & cell physiology 20051201

• Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study.

  Clinical chemistry 20051201

• Tri-nucleotide repeats and their association with genes in rice genome.

  Bio Systems 20051201

• OsGAP1 functions as a positive regulator of OsRab11-mediated TGN to PM or vacuole trafficking.

  Plant & cell physiology 20051201

• Quantitative measurement of serotonin synthesis and sequestration in individual live neuronal cells.

  Journal of neurochemistry 20051201

• Combining in silico tools and NMR data to validate protein-ligand structural models: application to matrix metalloproteinases.

  Journal of medicinal chemistry 20051201

• Platinum-based antitumor drugs containing enantiomerically pure alpha-trifluoromethyl alanine as ligand.

  Journal of medicinal chemistry 20051201

• Synthesis and pharmacology of willardiine derivatives acting as antagonists of kainate receptors.

  Journal of medicinal chemistry 20051201

• Radical scavengers: a remedy for presbyacusis. A pilot study.

  Acta oto-laryngologica 20051201

• The role of D1-Ala344 in charge stabilization and recombination in Photosystem II.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20051201

• SapT, a lanthionine-containing peptide involved in aerial hyphae formation in the streptomycetes.

  Molecular microbiology 20051201

• Arginine-rich motifs present multiple interfaces for specific binding by RNA.

  RNA (New York, N.Y.) 20051201

• Mild congenital primary hypothyroidism in a Turkish family caused by a homozygous missense thyrotropin receptor (TSHR) gene mutation (A593 V).

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20051201

• Trypsin inhibition by macrocyclic and open-chain variants of the squash inhibitor MCoTI-II.

  Biological chemistry 20051201

• The Ala45Thr polymorphism of NEUROD1 is associated with type 1 diabetes in Brazilian women.

  Diabetes & metabolism 20051201

• Two brothers with mild congenital erythropoietic porphyria due to a novel genotype.

  Archives of dermatology 20051201

• Imatinib binding and cKIT inhibition is abrogated by the cKIT kinase domain I missense mutation Val654Ala.

  Molecular cancer therapeutics 20051201

• Examining the relationships between the Pro12Ala variant in PPARG and Type 2 diabetes-related traits in UK samples.

  Diabetic medicine : a journal of the British Diabetic Association 20051201

• Systematic replacement of lysine with glutamine and alanine in Escherichia coli malate synthase G: effect on crystallization.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20051201

• Fe3+-hydroxide ligation in the superoxide reductase from Desulfoarculus baarsii is associated with pH dependent spectral changes.

  Journal of the American Chemical Society 20051130

• First report on the efficacy of l-alanine-based in situ-forming implants for the long-term parenteral delivery of drugs.

  Journal of controlled release : official journal of the Controlled Release Society 20051128

• Novel potential neuroprotective agents with both iron chelating and amino acid-based derivatives targeting central nervous system neurons.

  Biochemical pharmacology 20051125

• The ethyl pyruvate analogues, diethyl oxaloproprionate, 2-acetamidoacrylate, and methyl-2-acetamidoacrylate, exhibit anti-inflammatory properties in vivo and/or in vitro.

  Biochemical pharmacology 20051125

• Reversed DNA strand cleavage specificity in initiation of Cre-LoxP recombination induced by the His289Ala active-site substitution.

  Journal of molecular biology 20051125

• New routes to beta-cycloalkylalanine derivatives using serine-derived organozinc reagents.

  Organic & biomolecular chemistry 20051121

• A urokinase-type plasminogen activator-inhibiting cyclic peptide with an unusual P2 residue and an extended protease binding surface demonstrates new modalities for enzyme inhibition.

  The Journal of biological chemistry 20051118

• A novel peptidoglycan cross-linking enzyme for a beta-lactam-resistant transpeptidation pathway.

  The Journal of biological chemistry 20051118

• On the relationships of substrate orientation, hydrogen abstraction, and product stereochemistry in single and double dioxygenations by soybean lipoxygenase-1 and its Ala542Gly mutant.

  The Journal of biological chemistry 20051118

• Why is quinidine an inhibitor of cytochrome P450 2D6? The role of key active-site residues in quinidine binding.

  The Journal of biological chemistry 20051118

• Glucose 6-phosphate release of wild-type and mutant human brain hexokinases from mitochondria.

  The Journal of biological chemistry 20051118

• Selective determination of gamma-aminobutyric acid, glutamate and alanine by mixed micellar electrokinetic chromatography and fluorescence detection.

  Journal of chromatography. A 20051118

• Application of hydrophilic interaction liquid chromatography/comparative taste dilution analysis for identification of a bitter inhibitor by a combinatorial approach based on Maillard reaction chemistry.

  Journal of agricultural and food chemistry 20051116

• P61A mutation in the factor for inversion stimulation results in a thermostable dimeric intermediate.

  Biochemistry 20051115

• Thermodynamics and kinetics of formation of the alkaline state of a Lys 79-->Ala/Lys 73-->His variant of iso-1-cytochrome c.

  Biochemistry 20051115

• Chirality organization of ferrocenes bearing dipeptide chains of heterochiral sequence.

  Organic letters 20051110

• Conformation and orientation of tetraalanine in a lyotropic liquid crystal studied by nuclear magnetic resonance.

  The journal of physical chemistry. B 20051110

• Spontaneously formed vesicles of sodium N-(11-acrylamidoundecanoyl)-glycinate and L-alaninate in water.

  Langmuir : the ACS journal of surfaces and colloids 20051108

• Cryoreduction EPR and 13C, 19F ENDOR study of substrate-bound substates and solvent kinetic isotope effects in the catalytic cycle of cytochrome P450cam and its T252A mutant.

  Dalton transactions (Cambridge, England : 2003) 20051107

• Inhibition of hippocampal synaptic transmission by impairment of Ral function.

  Neuroreport 20051107

• Stereoselective lipases from Burkholderia sp., cloning and their application to preparation of methyl (R)-N-(2,6-dimethylphenyl)alaninate, a key intermediate for (R)-Metalaxyl.

  Journal of biotechnology 20051104

• Sterics and solvation winnow accessible conformational space for unfolded proteins.

  Journal of molecular biology 20051104

• Characterization and biocompatibility of organogels based on L-alanine for parenteral drug delivery implants.

  Biomaterials 20051101

• Amino acid metabolism of the porcine blastocyst.

  Theriogenology 20051101

• Fabrication of hydroxyapatite sponges by dextran sulphate/amino acid templating.

  Biomaterials 20051101

• Route-dependent effect of nutritional support on liver glucose uptake.

  American journal of physiology. Regulatory, integrative and comparative physiology 20051101

• L-Alanine induces changes in metabolic and signal transduction gene expression in a clonal rat pancreatic beta-cell line and protects from pro-inflammatory cytokine-induced apoptosis.

  Clinical science (London, England : 1979) 20051101

• Homology modeling identifies C-terminal residues that contribute to the Ca2+ sensitivity of a BKCa channel.

  Biophysical journal 20051101

• Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues.

  Journal of lipid research 20051101

• Detection of intracellular lactate with localized diffusion {1H-13C}-spectroscopy in rat glioma in vivo.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20051101

• Flexible charged macromolecules on mixed fluid lipid membranes: theory and Monte Carlo simulations.

  Biophysical journal 20051101

• A potential important role of skeletal muscle in human counterregulation of hypoglycemia.

  The Journal of clinical endocrinology and metabolism 20051101

• Essential cysteine residues in Bacillus subtilis spore photoproduct lyase identified by alanine scanning mutagenesis.

  Current microbiology 20051101

• Sequence variation in the human dopamine transporter gene in children with attention deficit hyperactivity disorder.

  Neuropharmacology 20051101

• Mapping the dose-effect relationship of orbofiban from sparse data with an artificial neural network.

  Journal of pharmaceutical sciences 20051101

• Expression studies of naturally occurring human dopamine transporter variants identifies a novel state of transporter inactivation associated with Val382Ala.

  Neuropharmacology 20051101

• Metabolic fates of ammonia-N in ruminal epithelial and duodenal mucosal cells isolated from growing sheep.

  Journal of dairy science 20051101

• The preferred conformation of the tripeptide Ala-Phe-Ala in water is an inverse gamma-turn: implications for protein folding and drug design.

  Biochemistry 20051101

• Redox and spectroscopic properties of human indoleamine 2,3-dioxygenase and a His303Ala variant: implications for catalysis.

  Biochemistry 20051101

• His374 of wheat endoxylanase inhibitor TAXI-I stabilizes complex formation with glycoside hydrolase family 11 endoxylanases.

  The FEBS journal 20051101

• Identification and characterization of a Na+-dependent neutral amino acid transporter, ASCT1, in rabbit corneal epithelial cell culture and rabbit cornea.

  Current eye research 20051101

• Thymic expression of mutated B16:A preproinsulin messenger RNA does not reverse acceleration of NOD diabetes associated with insulin 2 (thymic expressed insulin) knockout.

  Journal of autoimmunity 20051101

• Chemical synthesis of proteins and circular peptides using Nalpha-(1-phenyl-2-mercaptoethyl) auxiliaries.

  Protein and peptide letters 20051101

• The mechanism of intein-mediated protein splicing: variations on a theme.

  Protein and peptide letters 20051101

• Evidence for mitochondrial gene control of mating types in Phytophthora.

  Canadian journal of microbiology 20051101

• A mutation in Wolfram syndrome type 1 gene in a Japanese family with autosomal dominant low-frequency sensorineural hearing loss.

  Acta oto-laryngologica 20051101

• [Quality of ulcer healing and rebamipide].

  Nihon rinsho. Japanese journal of clinical medicine 20051101

• [Analysis of the coding region for signal peptide-containing proteins in Pseudomonas syringae pv. tomato genome].

  Yi chuan = Hereditas 20051101

• [Influence of polymorphism pro12Ala of PPARgamma gene on endothelium destruction in patients with diabetes mellitus t. 2].

  Polskie Archiwum Medycyny Wewnetrznej 20051101

• Structural and mutational analyses of the molecular interactions between the catalytic domain of factor XIa and the Kunitz protease inhibitor domain of protease nexin 2.

  The Journal of biological chemistry 20051028

• Probing the functionalities of alphaGlu328 and alphaAla74 of Vibrio harveyi luciferase by site-directed mutagenesis and chemical rescue.

  Biochemistry 20051025

• A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study.

  The Journal of biological chemistry 20051021

• A phosphorylation-dependent export structure in ROMK (Kir 1.1) channel overrides an endoplasmic reticulum localization signal.

  The Journal of biological chemistry 20051021

• Lanthionine introduction into nukacin ISK-1 prepeptide by co-expression with modification enzyme NukM in Escherichia coli.

  Biochemical and biophysical research communications 20051021

• Characterization of T cell receptors engineered for high affinity against toxic shock syndrome toxin-1.

  Journal of molecular biology 20051021

• Selective dye-labeling of newly synthesized proteins in bacterial cells.

  Journal of the American Chemical Society 20051019

• Hepatitis C virus NS3-4A serine protease inhibitors: use of a P2-P1 cyclopropyl alanine combination for improved potency.

  Bioorganic & medicinal chemistry letters 20051015

• Tumor-suppressive maspin regulates cell response to oxidative stress by direct interaction with glutathione S-transferase.

  The Journal of biological chemistry 20051014

• Identification of residues responsible for ligand recognition and regioisomeric selectivity of lysophosphatidic acid receptors expressed in mammalian cells.

  The Journal of biological chemistry 20051014

• Identification of the cyclamate interaction site within the transmembrane domain of the human sweet taste receptor subunit T1R3.

  The Journal of biological chemistry 20051007

• Insights into the human CD59 complement binding interface toward engineering new therapeutics.

  The Journal of biological chemistry 20051007

• Two-dimensional infrared spectra of the 13C=18O isotopomers of alanine residues in an alpha-helix.

  The journal of physical chemistry. B 20051006

• Theoretical study of volume changes associated with the helix-coil transition of an alanine-rich peptide in aqueous solution.

  Biopolymers 20051005

• An implementation of the nudged elastic band algorithm and application to the reaction mechanism of HGXPRTase from Plasmodium falciparum.

  Journal of molecular graphics & modelling 20051001

• QSAR study on carbonic anhydrase inhibitors: water-soluble sulfonamides incorporating beta-alanyl moieties, possessing long lasting-intra ocular pressure lowering properties--a molecular connectivity approach.

  European journal of medicinal chemistry 20051001

• Identification of novel targets of cephaloridine in rabbit renal proximal tubules synthesizing glutamine from alanine.

  Archives of toxicology 20051001

• The melanocortin-1 receptor carboxyl terminal pentapeptide is essential for MC1R function and expression on the cell surface.

  Peptides 20051001

• Direct determination of reaction paths and stationary points on potential of mean force surfaces.

  Journal of molecular graphics & modelling 20051001

• The 5alpha-reductase type II A49T and V89L high-activity allelic variants are more common in men with prostate cancer compared with the general population.

  European urology 20051001

• Selective cytotoxicity of azatyrosinamides against ras-transformed NIH 3T3 cells.

  Bioorganic & medicinal chemistry letters 20051001

• On the Ewald artifacts in computer simulations. The test-case of the octaalanine peptide with charged termini.

  Journal of biomolecular structure & dynamics 20051001

• Structure determination of aligned systems by solid-state NMR magic angle spinning methods.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20051001

• Mutation analysis of CLPTM 1 and PVRL 1 genes in patients with non-syndromic clefts of lip, alveolus and palate.

  Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 20051001

• Late-onset mitochondrial myopathy with dystrophic changes due to a G7497A mutation in the mitochondrial tRNA(Ser(UCN)) gene.

  Acta neuropathologica 20051001

• Stability of oxymethyl-modified coumarinic acid cyclic prodrugs of diastereomeric opioid peptides in biological media from various animal species including human.

  Journal of pharmaceutical sciences 20051001

• Association of the 1438G/A and 102T/C polymorphism of the 5-HT2A receptor gene with irritable bowel syndrome 5-HT2A gene polymorphism in irritable bowel syndrome.

  Journal of clinical gastroenterology 20051001

• Chemical synthesis of the RGD-protein decorsin: Pro-->Ala replacement reduces protein thermostability.

  Protein engineering, design & selection : PEDS 20051001

• Rebamipide, a gastro-protective drug, inhibits indomethacin-induced apoptosis in cultured rat gastric mucosal cells: association with the inhibition of growth arrest and DNA damage-induced 45 alpha expression.

  Digestive diseases and sciences 20051001

• Direct autoradiographic evidence that rebamipide interacts with neutrophils in dextran sulfate sodium induced colitis in rats.

  Digestive diseases and sciences 20051001

• Rebamipide enemas-new effective treatment for patients with corticosteroid dependent or resistant ulcerative colitis.

  Digestive diseases and sciences 20051001

• Rebamipide enema is effective for treatment of experimental dextran sulfate sodium induced colitis in rats.

  Digestive diseases and sciences 20051001

• 15th anniversary of rebamipide: looking ahead to the new mechanisms and new applications.

  Digestive diseases and sciences 20051001

• Rebamipide decreases the susceptibility of gastric mucosa to acid-induced injury in rats by inhibiting neutrophil activation.

  Digestive diseases and sciences 20051001

• Rebamipide reduces delay in gastric ulcer healing in cyclooxygenase-2-deficient mice.

  Digestive diseases and sciences 20051001

• Gastro-protective agent rebamipide induces cyclooxygenease-2 (COX-2) in gastric epithelial cells.

  Digestive diseases and sciences 20051001

• Rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial RGM-1 cells.

  Digestive diseases and sciences 20051001

• Rebamipide reduces indomethacin-induced gastric injury in mice via down-regulation of ICAM-1 expression.

  Digestive diseases and sciences 20051001

• Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils.

  Digestive diseases and sciences 20051001

• Prevention by rebamipide of acute reflux esophagitis in rats.

  Digestive diseases and sciences 20051001

• Kinetics of the interaction of sulfate and hydrogen phosphate radicals with small peptides of glycine, alanine, tyrosine and tryptophan.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20051001

• Collagen morphology is not associated with the Ala549Pro polymorphism of the COL1A2 gene.

  Stroke 20051001

• Evidence from 13C solid-state NMR spectroscopy for a lamella structure in an alanine-glycine copolypeptide: a model for the crystalline domain of Bombyx mori silk fiber.

  Protein science : a publication of the Protein Society 20051001

• A non-conservative, coding single-nucleotide polymorphism in the N-terminal region of lactoferrin is associated with aggressive periodontitis in an African-American, but not a Caucasian population.

  Genes and immunity 20051001

• Transition pathways in complex systems: Application of the finite-temperature string method to the alanine dipeptide.

  The Journal of chemical physics 20051001

• Catalytic activities of [GADV]-peptides. Formation and establishment of [GADV]-protein world for the emergence of life.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20051001

• Retinoylserine and retinoylalanine, natural products of the moth Trichoplusia ni.

  Journal of natural products 20051001

• Crystallization and preliminary X-ray crystallographic study of the wild type and two mutants of the CP1 hydrolytic domain from Aquifex aeolicus leucyl-tRNA synthetase.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20051001

• Animal model of oculopharyngeal muscular dystrophy.

  Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology 20051001

• X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum.

  The Journal of biological chemistry 20050930

• LMP1 protein from the Epstein-Barr virus is a structural CD40 decoy in B lymphocytes for binding to TRAF3.

  The Journal of biological chemistry 20050930

• Dephosphorylation of Ser-226 facilitates plasma membrane retention of Ntcp.

  The Journal of biological chemistry 20050930

• Chemical rescue of I-site cleavage in living cells and in vitro discriminates between the cytomegalovirus protease, assemblin, and its precursor, pUL80a.

  The Journal of biological chemistry 20050930

• An on-pathway hidden intermediate and the early rate-limiting transition state of Rd-apocytochrome b562 characterized by protein engineering.

  Journal of molecular biology 20050930

• Dimerization of doublesex is mediated by a cryptic ubiquitin-associated domain fold: implications for sex-specific gene regulation.

  The Journal of biological chemistry 20050923

• Identification of factor Xa residues critical for interaction with protein Z-dependent protease inhibitor: both active site and exosite interactions are required for inhibition.

  The Journal of biological chemistry 20050923

• Use of microcoil probehead for determination of the structure of oriented silk fibers by solid-state NMR.

  The journal of physical chemistry. B 20050922

• Identification of determinants of ligand binding affinity and selectivity in the prostaglandin D2 receptor CRTH2.

  The Journal of biological chemistry 20050916

• Effect of multiple prolyl isomerization reactions on the stability and folding kinetics of the notch ankyrin domain: experiment and theory.

  Journal of molecular biology 20050916

• Repressor domain and nuclear localization signal of the murine Hoxa-11 protein are located in the homeodomain: no evidence for role of poly alanine stretches in transcriptional repression.

  Journal of experimental zoology. Part B, Molecular and developmental evolution 20050915

• Effects of the sequence and size of non-polar residues on self-assembly of amphiphilic peptides.

  International journal of biological macromolecules 20050915

• The heat transfer analysis of nanoparticle heat source in alanine tissue by molecular dynamics.

  International journal of biological macromolecules 20050915

• Cadherin adhesion depends on a salt bridge at the N-terminus.

  Journal of cell science 20050915

• BAD Ser128 is not phosphorylated by c-Jun NH2-terminal kinase for promoting apoptosis.

  Cancer research 20050915

• Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis.

  Genes & development 20050915

• Prediction of progression to cirrhosis by a glutathione S-transferase P1 polymorphism in subjects with hereditary hemochromatosis.

  Archives of internal medicine 20050912

• The common A467T mutation in the human mitochondrial DNA polymerase (POLG) compromises catalytic efficiency and interaction with the accessory subunit.

  The Journal of biological chemistry 20050909

• Individual subunits of the glutamate transporter EAAC1 homotrimer function independently of each other.

  Biochemistry 20050906

• Dissociation of alkaliated alanine in the gas phase: the role of the metal cation.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20050905

• Generalized hybrid-orbital method for combining density functional theory with molecular mechanicals.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20050905

• D-Serine uptake by isolated retinas is consistent with ASCT-mediated transport.

  Neuroscience letters 20050902

• Divergent pharmacological activity of novel marine-derived excitatory amino acids on glutamate receptors.

  The Journal of pharmacology and experimental therapeutics 20050901

• Hydroxide and proton migration in aquaporins.

  Biophysical journal 20050901

• The Gln4863Ala mutation within a putative, pore-lining trans-membrane helix of the cardiac ryanodine receptor channel alters both the kinetics of ryanoid interaction and the subsequent fractional conductance.

  Molecular pharmacology 20050901

• Dynamic changes in protein-protein interaction and protein phosphorylation probed with amine-reactive isotope tag.

  Molecular & cellular proteomics : MCP 20050901

• Isolation and characterization of hemolymph antifreeze proteins from larvae of the longhorn beetle Rhagium inquisitor (L.).

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050901

• Potentials of mean force for the interaction of blocked alanine dipeptide molecules in water and gas phase from MD simulations.

  Biophysical journal 20050901

• A novel homozygous Ala529Val LMNA mutation in Turkish patients with mandibuloacral dysplasia.

  The Journal of clinical endocrinology and metabolism 20050901

• Terahertz time-domain spectroscopy of amino acids and polypeptides.

  Biophysical journal 20050901

• Interleukin-15 decreases proteolysis in skeletal muscle: a direct effect.

  International journal of molecular medicine 20050901

• Novel endomorphin-2 analogs with mu-opioid receptor antagonist activity.

  The journal of peptide research : official journal of the American Peptide Society 20050901

• [Ala12]MCD peptide: a lead peptide to inhibitors of immunoglobulin E binding to mast cell receptors.

  The journal of peptide research : official journal of the American Peptide Society 20050901

• Two proline-rich peptides from pig (Sus scrofa) salivary glands generated by pre-secretory pathway underlying the action of a proteinase cleaving ProAla bonds.

  Peptides 20050901

• LY-544344. Eli Lilly.

  IDrugs : the investigational drugs journal 20050901

• A crystallographic study of Cys69Ala flavodoxin II from Azotobacter vinelandii: structural determinants of redox potential.

  Protein science : a publication of the Protein Society 20050901

• Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis.

  Protein science : a publication of the Protein Society 20050901

• An improved experimental system for determining small folding entropy changes resulting from proline to alanine substitutions.

  Protein science : a publication of the Protein Society 20050901

• Physiological function and metabolism of free D-alanine in aquatic animals.

  Biological & pharmaceutical bulletin 20050901

• Ala160 and His116 residues are involved in activity and specificity of apyrase, an ATP-hydrolysing enzyme produced by enteroinvasive Escherichia coli.

  Microbiology (Reading, England) 20050901

• Signal peptide hydrophobicity is critical for early stages in protein export by Bacillus subtilis.

  The FEBS journal 20050901

• Association study of Glutathione S-transferase P1 (GSTP1) with asthma and bronchial hyper-responsiveness in two German pediatric populations.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20050901

• [Proton magnetic resonance spectroscopy (1H-MRS) for the diagnosis of brain tumors and the evaluation of treatment].

  Neuro-Chirurgie 20050901

• [Synthesis and spectral characterization of rare earth complexes of acylpyrazolone-beta-alanine].

  Guang pu xue yu guang pu fen xi = Guang pu 20050901

• Collagen production in cardiac fibroblasts during inhibition of aminopeptidase B.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20050901

• Enhanced proliferative potential of hematopoietic cells expressing degradation-resistant c-Myb mutants.

  The Journal of biological chemistry 20050826

• Interaction of the Ty3 reverse transcriptase thumb subdomain with template-primer.

  The Journal of biological chemistry 20050826

• Evidence for a granule targeting sequence within platelet factor 4.

  The Journal of biological chemistry 20050826

• SET8 recognizes the sequence RHRK20VLRDN within the N terminus of histone H4 and mono-methylates lysine 20.

  The Journal of biological chemistry 20050826

• Protein kinase A-dependent phosphorylation of Lutheran/basal cell adhesion molecule glycoprotein regulates cell adhesion to laminin alpha5.

  The Journal of biological chemistry 20050826

• Cleavage of p21/WAF1/CIP1 by proteinase 3 modulates differentiation of a monocytic cell line. Molecular analysis of the cleavage site.

  The Journal of biological chemistry 20050826

• Sequential phosphorylation mediates receptor- and kinase-induced inhibition of TREK-1 background potassium channels.

  The Journal of biological chemistry 20050826

• Gas-phase models of gamma turns: effect of side-chain/backbone interactions investigated by IR/UV spectroscopy and quantum chemistry.

  The Journal of chemical physics 20050822

• Rebamipide inhibits gastric cancer growth by targeting survivin and Aurora-B.

  Biochemical and biophysical research communications 20050819

• Long dynamics simulations of proteins using atomistic force fields and a continuum representation of solvent effects: calculation of structural and dynamic properties.

  Proteins 20050815

• Substitution of a conserved alanine in the domain IIIS4-S5 linker of the cardiac sodium channel causes long QT syndrome.

  Cardiovascular research 20050815

• Inhibitor-assisted refolding of protease: a protease inhibitor as an intramolecular chaperone.

  FEBS letters 20050815

• The leucine 10 residue in the pleckstrin homology domain of ceramide kinase is crucial for its catalytic activity.

  FEBS letters 20050815

• The crystal structure of Mlc, a global regulator of sugar metabolism in Escherichia coli.

  The Journal of biological chemistry 20050812

• Key role of conserved histidines in recombinant mouse beta-carotene 15,15'-monooxygenase-1 activity.

  The Journal of biological chemistry 20050812

• Identification of Ser153 in ICL2 of the gonadotropin-releasing hormone (GnRH) receptor as a phosphorylation-independent site for inhibition of Gq coupling.

  The Journal of biological chemistry 20050812

• Dipeptides as effective prodrugs of the unnatural amino acid (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740), a selective group II metabotropic glutamate receptor agonist.

  Journal of medicinal chemistry 20050811

• Vacuum-ultraviolet electronic circular dichroism of L-alanine in aqueous solution investigated by time-dependent density functional theory.

  The journal of physical chemistry. A 20050811

• Mutagenesis of Ala290, which modulates substrate subsite affinity at the catalytic interface of dimeric ThMA.

  Biochimica et biophysica acta 20050810

• Transition state stabilization by six arginines clustered in the active site of creatine kinase.

  Biochimica et biophysica acta 20050810

• Parallel beta-sheets and polar zippers in amyloid fibrils formed by residues 10-39 of the yeast prion protein Ure2p.

  Biochemistry 20050809

• Functional mapping of charged residues of the 82-116 sequence in factor Xa: evidence that lysine 96 is a factor Va independent recognition site for prothrombin in the prothrombinase complex.

  Biochemistry 20050802

• Biphasic kinetics of the colchicine-tubulin interaction: role of amino acids surrounding the A ring of bound colchicine molecule.

  Biochemistry 20050802

• A Glu113Ala mutation within a factor VIII Ca2+-binding site enhances cofactor interactions in factor Xase.

  Biochemistry 20050802

• Mouse oocytes regulate metabolic cooperativity between granulosa cells and oocytes: amino acid transport.

  Biology of reproduction 20050801

• Structure and stability of beta-pleated sheets.

  Journal of computational chemistry 20050801

• Cognitive effects of dopaminergic and glutamatergic blockade in nucleus accumbens in pigeons.

  Pharmacology, biochemistry, and behavior 20050801

• The recycling of carbon in glucose, lactate and alanine in sheep.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20050801

• Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors.

  American journal of human genetics 20050801

• Zonation of alanine metabolism in the bivascularly perfused rat liver.

  Liver international : official journal of the International Association for the Study of the Liver 20050801

• Structure of the wild-type TEM-1 beta-lactamase at 1.55 A and the mutant enzyme Ser70Ala at 2.1 A suggest the mode of noncovalent catalysis for the mutant enzyme.

  Acta crystallographica. Section D, Biological crystallography 20050801

• Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance.

  Molecular and cellular biology 20050801

• Coexpression of formylglycine-generating enzyme is essential for synthesis and secretion of functional arylsulfatase A in a mouse model of metachromatic leukodystrophy.

  Human gene therapy 20050801

• Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion.

  Journal of neurochemistry 20050801

• Cephalosporin-resistant pneumococci and sickle cell disease.

  Emerging infectious diseases 20050801

• Influence of the C161T but not Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma on colorectal cancer in an Indian population.

  Cancer science 20050801

• Association of severe micropenis with Gly146Ala polymorphism in the gene for steroidogenic factor-1.

  Endocrine journal 20050801

• Alternate pathways of thyroid hormone metabolism.

  Thyroid : official journal of the American Thyroid Association 20050801

• The prevalence of C807T mutation of glycoprotein Ia gene among young male survivors of myocardial infarction: a relation with coronary angiography results.

  Kardiologia polska 20050801

• COX-1 and COX-2 conversely promote and suppress ischemia-reperfusion gastric injury in mice.

  Scandinavian journal of gastroenterology 20050801

• Population pharmacokinetic-pharmacodynamic modeling of subcutaneous and pulmonary insulin in rats.

  Journal of pharmacokinetics and pharmacodynamics 20050801

• Degradation of metalaxyl and mefenoxam and effects on the microbiological properties of tropical and temperate soils.

  International journal of environmental research and public health 20050801

• Chimeric mutations in the M2 segment of the 5-hydroxytryptamine-gated chloride channel MOD-1 define a minimal determinant of anion/cation permeability.

  The Journal of biological chemistry 20050729

• Microbiology. Translocation of anthrax toxin: lord of the rings.

  Science (New York, N.Y.) 20050729

• Acyclic amino acid-catalyzed direct asymmetric aldol reactions: alanine, the simplest stereoselective organocatalyst.

  Chemical communications (Cambridge, England) 20050728

• Neighbor effect on PPII conformation in alanine peptides.

  Journal of the American Chemical Society 20050727

• Biological, biochemical, and kinetic effects of mutations of the cardiomyopathy loop of Dictyostelium myosin II: importance of ALA400.

  The Journal of biological chemistry 20050722

• Alanine scanning mutants of the HIV gp41 loop.

  The Journal of biological chemistry 20050722

• Characterization of the restricted rotation of the dimethyl groups in chemically N-terminal 13C-labeled antifreeze glycoproteins: a temperature-dependent study in water to ice through the supercooled state.

  The Journal of chemical physics 20050722

• Stereoselective synthesis of alpha-C-glucosyl serine and alanine via a cross-metathesis/cyclization strategy.

  Organic letters 20050721

• Molecular dynamics with the united-residue model of polypeptide chains. I. Lagrange equations of motion and tests of numerical stability in the microcanonical mode.

  The journal of physical chemistry. B 20050721

• Investigation of the relationship between protein-protein interaction and catalytic activity of a heme-regulated phosphodiesterase from Escherichia coli (Ec DOS) by protein microarray.

  Biochemistry 20050719

• Functional characterization and ATP-induced dimerization of the isolated ABC-domain of the haemolysin B transporter.

  Biochemistry 20050719

• Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells.

  FEBS letters 20050718

• A novel assay method for an amino acid racemase reaction based on circular dichroism.

  The Biochemical journal 20050715

• Novel 3'-ribonuclease and 3'-phosphatase activities of the bacterial non-homologous end-joining protein, DNA ligase D.

  The Journal of biological chemistry 20050715

• Critical hydrophobic interactions between phosphorylation and actuator domains of Ca2+-ATPase for hydrolysis of phosphorylated intermediate.

  The Journal of biological chemistry 20050715

• BAD detects coincidence of G2/M phase and growth factor deprivation to regulate apoptosis.

  The Journal of biological chemistry 20050715

• Phosphorylation of the yeast choline kinase by protein kinase C. Identification of Ser25 and Ser30 as major sites of phosphorylation.

  The Journal of biological chemistry 20050715

• Functional analysis of the Ala67Thr polymorphism in agouti related protein associated with anorexia nervosa and leanness.

  Biochemical pharmacology 20050715

• Hierarchical regulation of CTLA-4 dimer-based lattice formation and its biological relevance for T cell inactivation.

  Journal of immunology (Baltimore, Md. : 1950) 20050715

• Mutational analysis of the human 2B4 (CD244)/CD48 interaction: Lys68 and Glu70 in the V domain of 2B4 are critical for CD48 binding and functional activation of NK cells.

  Journal of immunology (Baltimore, Md. : 1950) 20050715

• Mutation of the adenylylated tyrosine of glutamine synthetase alters its catalytic properties.

  Biochemistry 20050712

• Purification and biochemical characterization of a pyruvate-specific class II aldolase, HpaI.

  Biochemistry 20050712

• Shotgun alanine scanning shows that growth hormone can bind productively to its receptor through a drastically minimized interface.

  The Journal of biological chemistry 20050708

• Structure of the G60A mutant of Ras: implications for the dominant negative effect.

  The Journal of biological chemistry 20050708

• A new scheme for determining the intramolecular seven-membered ring N-H...O=C hydrogen-bonding energies of glycine and alanine peptides.

  The Journal of chemical physics 20050708

• Cell-penetrating cis-gamma-amino-l-proline-derived peptides.

  Journal of the American Chemical Society 20050706

• Preliminary crystallographic analysis of the Cks protein p13(suc1P90AP92A) from Schizosacharromyces pombe.

  European biophysics journal : EBJ 20050701

• Domain 2 of the urokinase receptor contains an integrin-interacting epitope with intrinsic signaling activity: generation of a new integrin inhibitor.

  The Journal of biological chemistry 20050701

• Cross-talk between fMLP and vitronectin receptors triggered by urokinase receptor-derived SRSRY peptide.

  The Journal of biological chemistry 20050701

• Functional characterization of the iron-regulatory transcription factor Fep1 from Schizosaccharomyces pombe.

  The Journal of biological chemistry 20050701

• Identification and structural determination of the M(3) muscarinic acetylcholine receptor basolateral sorting signal.

  The Journal of biological chemistry 20050701

• Phosphorylation-independent regulation of metabotropic glutamate receptor 1 signaling requires g protein-coupled receptor kinase 2 binding to the second intracellular loop.

  The Journal of biological chemistry 20050701

• A founder mutation in the CLCNKB gene causes Bartter syndrome type III in Spain.

  Pediatric nephrology (Berlin, Germany) 20050701

• An essential tryptophan of Escherichia coli DnaA protein functions in oligomerization at the E. coli replication origin.

  The Journal of biological chemistry 20050701

• Molecular genetics of hereditary prothrombin deficiency in Indian patients: identification of a novel Ala362 --> Thr (Prothrombin Vellore 1) mutation.

  Journal of thrombosis and haemostasis : JTH 20050701

• MRL/lpr mice have alterations in brain metabolism as shown with [1H-13C] NMR spectroscopy.

  Neurochemistry international 20050701

• Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response.

  Neurochemistry international 20050701

• Condensation properties of vesicles formed from an amphiphilic N-phosphorylamino acid.

  Journal of colloid and interface science 20050701

• Energetics and cooperativity of the hydrogen bonding and anchor interactions that bind peptides to MHC class II protein.

  Journal of molecular biology 20050701

• Fluorogenic peptide substrates containing benzoxazol-5-yl-alanine derivatives for kinetic assay of cysteine proteases.

  Analytical biochemistry 20050701

• Studies of relationships between the GLUT10 Ala206Thr polymorphism and impaired insulin secretion.

  Diabetic medicine : a journal of the British Diabetic Association 20050701

• Inverse effects of the PPAR(gamma)2 Pro12Ala polymorphism on measures of adiposity over 15 years in African Americans and whites. The CARDIA study.

  Metabolism: clinical and experimental 20050701

• L-alanylglycyl-L-alanine monohydrate at 20 K.

  Acta crystallographica. Section C, Crystal structure communications 20050701

• Catalytic residues Lys197 and Arg199 of Bacillus subtilis phosphoribosyl diphosphate synthase. Alanine-scanning mutagenesis of the flexible catalytic loop.

  The FEBS journal 20050701

• Role of GSK-3beta activity in motor neuronal cell death induced by G93A or A4V mutant hSOD1 gene.

  The European journal of neuroscience 20050701

• Plasma amino acid concentrations in patients with coronary heart disease: a comparison between U.K. Indian Asian and Caucasian men.

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20050701

• Role of aspartic acid 121 in human pancreatic ribonuclease catalysis.

  Molecular and cellular biochemistry 20050701

• Characterization of a bifunctional PutA homologue from Bradyrhizobium japonicum and identification of an active site residue that modulates proline reduction of the flavin adenine dinucleotide cofactor.

  Biochemistry 20050628

• Versatile and stereoselective syntheses of orthogonally protected beta-methylcysteine and beta-methyllanthionine.

  Organic letters 20050623

• Characterization of the conformational probability of N-acetyl-phenylalanyl-NH2 by RHF, DFT, and MP2 computation and AIM analyses, confirmed by jet-cooled infrared data.

  The journal of physical chemistry. A 20050623

• Polypeptide foldings obtained with effective pair potentials.

  The Journal of chemical physics 20050622

• Lantibiotic structures as guidelines for the design of peptides that can be modified by lantibiotic enzymes.

  Biochemistry 20050621

• The N-acetyl-D-glucosaminylphosphatidylinositol De-N-acetylase of glycosylphosphatidylinositol biosynthesis is a zinc metalloenzyme.

  The Journal of biological chemistry 20050617

• Receptor epitope usage by an interleukin-5 mimetic peptide.

  The Journal of biological chemistry 20050617

• Mutation of Cys105 inhibits dimerization of p12CDK2-AP1 and its growth suppressor effect.

  The Journal of biological chemistry 20050617

• The selectivity filter of the cation channel TRPM4.

  The Journal of biological chemistry 20050617

• Replacement of Phe6, Phe7, and Phe11 of D-Trp8-somatostatin-14 with L-pyrazinylalanine. Predicted and observed effects on binding affinities at hSST2 and hSST4. An unexpected effect of the chirality of Trp8 on NMR spectra in methanol.

  Journal of medicinal chemistry 20050616

• Selective measurement of heteronuclear 1H-13C dipolar couplings in motionally heterogeneous semicrystalline polymer systems.

  The journal of physical chemistry. A 20050616

• Pressure-tuning FT-IR spectroscopic study on the helix-coil transition of Ala-rich oligopeptide in aqueous solution.

  Biochimica et biophysica acta 20050615

• Identification of NH(2)-terminal amino acid residues essential for the biological activity of leukotactin-1.

  Immunology letters 20050615

• Substituting c-Jun N-terminal kinase-3 (JNK3) ATP-binding site amino acid residues with their p38 counterparts affects binding of JNK- and p38-selective inhibitors.

  Archives of biochemistry and biophysics 20050615

• Single amino acid substitution in the putative transmembrane helix V in KdpB of the KdpFABC complex of Escherichia coli uncouples ATPase activity and ion transport.

  Biochemistry 20050614

• Analysis of active site residues of botulinum neurotoxin E by mutational, functional, and structural studies: Glu335Gln is an apoenzyme.

  Biochemistry 20050614

• Agrobacterium phytochrome as an enzyme for the production of ZZE bilins.

  Biochemistry 20050614

• Crystal structures of the ferrous dioxygen complex of wild-type cytochrome P450eryF and its mutants, A245S and A245T: investigation of the proton transfer system in P450eryF.

  The Journal of biological chemistry 20050610

• A systematic mutagenesis study of Ile-282 in transmembrane segment M4 of the plasma membrane H+-ATPase.

  The Journal of biological chemistry 20050610

• Stereoselective syntheses of 4-hydroxy 4-substituted glutamic acids.

  The Journal of organic chemistry 20050610

• Binding of the UvrB dimer to non-damaged and damaged DNA: residues Y92 and Y93 influence the stability of both subunits.

  DNA repair 20050608

• A small-molecule-based approach to sense codon-templated natural-unnatural hybrid peptides. Selective silencing and reassignment of the sense codon by orthogonal reacylation stalling at the single-codon level.

  Journal of the American Chemical Society 20050608

• Oxidative reactivity of Cu-TESHHK- and its alanine analogues.

  Dalton transactions (Cambridge, England : 2003) 20050607

• Removal of a methyl group causes global changes in p-hydroxybenzoate hydroxylase.

  Biochemistry 20050607

• Contribution of polar residues of the J-helix in the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): Q677 regulates the removal of terminal mismatch.

  Biochemistry 20050607

• Phosphorylation of the RGS protein Sst2 by the MAP kinase Fus3 and use of Sst2 as a model to analyze determinants of substrate sequence specificity.

  Biochemistry 20050607

• Egg case protein-1. A new class of silk proteins with fibroin-like properties from the spider Latrodectus hesperus.

  The Journal of biological chemistry 20050603

• Characterization of the functional insulin binding epitopes of the full-length insulin receptor.

  The Journal of biological chemistry 20050603

• Effect of glutamine on water and sodium absorption in human jejunum at baseline and during PGE1-induced secretion.

  Journal of applied physiology (Bethesda, Md. : 1985) 20050601

• Using 2H2O to study the influence of feeding on protein synthesis: effect of isotope equilibration in vivo vs. in cell culture.

  American journal of physiology. Endocrinology and metabolism 20050601

• Contribution of L-3,4-dihydroxyphenylalanine metabolism to the inhibition of gluconeogenesis in rabbit kidney-cortex tubules.

  The international journal of biochemistry & cell biology 20050601

• The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus.

  The Journal of clinical endocrinology and metabolism 20050601

• Analysis of separate and combined effects of common variation in KCNJ11 and PPARG on risk of type 2 diabetes.

  The Journal of clinical endocrinology and metabolism 20050601

• Helix-coil transition of alanine peptides in water: force field dependence on the folded and unfolded structures.

  Proteins 20050601

• p38 Mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211.

  Molecular endocrinology (Baltimore, Md.) 20050601

• Computational analysis of molecular basis of 1:1 interactions of NRG-1beta wild-type and variants with ErbB3 and ErbB4.

  Proteins 20050601

• Type and location of fluorescent probes incorporated into the potent mu-opioid peptide [Dmt]DALDA affect potency, receptor selectivity and intrinsic efficacy.

  The journal of peptide research : official journal of the American Peptide Society 20050601

• H662 is the linchpin of ATP hydrolysis in the nucleotide-binding domain of the ABC transporter HlyB.

  The EMBO journal 20050601

• Synthesis of cyclic endiamino peptides.

  Journal of the American Chemical Society 20050601

• Analysis of a 17-amino acid residue, virus-neutralizing microantibody.

  The Journal of general virology 20050601

• Vitreous amyloidosis in alanine 71 transthyretin mutation.

  The British journal of ophthalmology 20050601

• N-terminal acetylation and protonation of individual hemoglobin subunits: position-dependent effects on tetramer strength and cooperativity.

  Protein science : a publication of the Protein Society 20050601

• The alpha helix dipole: screened out?

  Structure (London, England : 1993) 20050601

• Substrate positioning by His92 is important in catalysis by purple acid phosphatase.

  The FEBS journal 20050601

• Inhibition of the D-alanine:D-alanyl carrier protein ligase from Bacillus subtilis increases the bacterium's susceptibility to antibiotics that target the cell wall.

  The FEBS journal 20050601

• A DmpA-homologous protein from Pseudomonas sp. is a dipeptidase specific for beta-alanyl dipeptides.

  The FEBS journal 20050601

• SCN9A mutations define primary erythermalgia as a neuropathic disorder of voltage gated sodium channels.

  The Journal of investigative dermatology 20050601

• Intestinal D-glucose and L-alanine transport in Japanese quail (Coturnix coturnix).

  Poultry science 20050601

• Stereochemical heterogeneity in Verongid sponge metabolites. Absolute stereochemistry of (+)-fistularin-3 and (+)-11-epi-fistularin-3 by microscale LCMS-Marfey's analysis.

  Journal of natural products 20050601

• Antibacterial activities and bonding of MMSA/TBB resin containing amphiphilic lipids.

  Dental materials journal 20050601

• DNA-sequence determination of exon 2 of a novel HLA-DPB1 allele, HLA-DPB1*0403.

  DNA sequence : the journal of DNA sequencing and mapping 20050601

• D-Amino acid dipeptide production utilizing D-alanine-D-alanine ligases with novel substrate specificity.

  Journal of bioscience and bioengineering 20050601

• Conserved glycine residues in the cytoplasmic domain of the aspartate receptor play essential roles in kinase coupling and on-off switching.

  Biochemistry 20050531

• Study of alanine-73 and aspartate-9 of HLA-C locus in Saudi psoriasis patients, using sequence-specific primers (PCR-SSP).

  Journal of biochemistry and molecular biology 20050531

• Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme.

  Cell 20050520

• Site-directed mutagenesis of proline 94 to alanine in amicyanin converts a true electron transfer reaction into one that is kinetically coupled.

  Biochemistry 20050517

• Aggregation of a slow-folding mutant of a beta-clam protein proceeds through a monomeric nucleus.

  Biochemistry 20050517

• Calcium-binding properties of wild-type and EF-hand mutants of S100B in the presence and absence of a peptide derived from the C-terminal negative regulatory domain of p53.

  Biochemistry 20050517

• Mechanism of zinc coordination by point-mutated structures of the distal CCHC binding motif of the HIV-1 NCp7 protein.

  Biochemistry 20050517

• Mutation of surface cysteine 374 to alanine in monoamine oxidase A alters substrate turnover and inactivation by cyclopropylamines.

  Bioorganic & medicinal chemistry 20050516

• Synthesis of dehydroalanine fragments as thiostrepton side chain mimetics.

  Bioorganic & medicinal chemistry letters 20050516

• A common docking site for response regulators on the yeast phosphorelay protein YPD1.

  Biochimica et biophysica acta 20050515

• The structure of Apo R268A human aldose reductase: hinges and latches that control the kinetic mechanism.

  Biochimica et biophysica acta 20050515

• Heterologous expression, purification, crystallization, X-ray analysis and phasing of the acetyl xylan esterase from Bacillus pumilus.

  Biochimica et biophysica acta 20050515

• FAD semiquinone stability regulates single- and two-electron reduction of quinones by Anabaena PCC7119 ferredoxin:NADP+ reductase and its Glu301Ala mutant.

  Archives of biochemistry and biophysics 20050515

• Low binding capacity of murine tetramers mutated at residue 227 does not preclude the ability to efficiently activate CD8+ T lymphocytes.

  Immunology letters 20050515

• Role of lipoteichoic acid in the phagocyte response to group B streptococcus.

  Journal of immunology (Baltimore, Md. : 1950) 20050515

• Palmitoylated cysteine 192 is required for RhoB tumor-suppressive and apoptotic activities.

  The Journal of biological chemistry 20050513

• Functional dissection of an AP-2 beta2 appendage-binding sequence within the autosomal recessive hypercholesterolemia protein.

  The Journal of biological chemistry 20050513

• Identification and functional characterization of a novel low affinity aromatic-preferring amino acid transporter (arpAT). One of the few proteins silenced during primate evolution.

  The Journal of biological chemistry 20050513

• Aspartate 120 of Escherichia coli methylenetetrahydrofolate reductase: evidence for major roles in folate binding and catalysis and a minor role in flavin reactivity.

  Biochemistry 20050510

• Point mutations at the type I Cu ligands, Cys457 and Met467, and at the putative proton donor, Asp105, in Myrothecium verrucaria bilirubin oxidase and reactions with dioxygen.

  Biochemistry 20050510

• Switching pyridine nucleotide specificity in P450 BM3: mechanistic analysis of the W1046H and W1046A enzymes.

  The Journal of biological chemistry 20050506

• LINE-1 retrotransposition requires the nucleic acid chaperone activity of the ORF1 protein.

  Journal of molecular biology 20050506

• The disulfide linkage and the free sulfhydryl accessibility of acyl-coenzyme A:cholesterol acyltransferase 1 as studied by using mPEG5000-maleimide.

  Biochemistry 20050503

• Ligand-free and -bound structures of the binding protein (LivJ) of the Escherichia coli ABC leucine/isoleucine/valine transport system: trajectory and dynamics of the interdomain rotation and ligand specificity.

  Biochemistry 20050503

• Structural studies on the reaction of isopenicillin N synthase with the truncated substrate analogues delta-(L-alpha-aminoadipoyl)-L-cysteinyl-glycine and delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alanine.

  Biochemistry 20050503

• Functional characterization of N-terminal nucleotide binding domain (NBD-1) of a major ABC drug transporter Cdr1p of Candida albicans: uncommon but conserved Trp326 of Walker B is important for ATP binding.

  Biochemistry 20050503

• Identification of a membrane-localized cysteine cluster near the substrate-binding sites of the Streptococcus equisimilis hyaluronan synthase.

  Glycobiology 20050501

• Alcohol intake modulates the genetic association between HDL cholesterol and the PPARgamma2 Pro12Ala polymorphism.

  Journal of lipid research 20050501

• Measurement of estrogen effect on bone turnover by 2H2O labeling.

  Calcified tissue international 20050501

• Quantitative measurement of changes in amyloid-beta(40) in the rat brain and cerebrospinal fluid following treatment with the gamma-secretase inhibitor LY-411575 [N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide].

  The Journal of pharmacology and experimental therapeutics 20050501

• Exogenous supply of pantoyl lactone to excised leaves increases their pantothenate levels.

  Annals of botany 20050501

• A non-sequence-specific requirement for SMN protein activity: the role of aminoglycosides in inducing elevated SMN protein levels.

  Human molecular genetics 20050501

• Sauvagine analogs selective for corticotropin releasing factor 2 receptor: effect of substitutions at positions 35 and 39 on CRF2R selectivity.

  Peptides 20050501

• Genetic approaches to studying common diseases and complex traits.

  Pediatric research 20050501

• Constitutive expression of yeast phospholipid biosynthetic genes by variants of Ino2 activator defective for interaction with Opi1 repressor.

  Molecular microbiology 20050501

• Effects of KATP channel modulation on myocardial glycogen content, lactate, and amino acids in nonischemic and ischemic rat hearts.

  Journal of cardiovascular pharmacology 20050501

• The first enantioselective synthesis of the amavadin ligand and its complexation to vanadium.

  Journal of inorganic biochemistry 20050501

• Dilated cardiomyopathy may be an early sign of the C826A Fukutin-related protein mutation.

  Neuromuscular disorders : NMD 20050501

• The manganese superoxide dismutase Ala16Val dimorphism modulates both mitochondrial import and mRNA stability.

  Pharmacogenetics and genomics 20050501

• Functional analysis of recombinant Bbeta15C and Bbeta15A fibrinogens demonstrates that Bbeta15G residue plays important roles in FPB release and in lateral aggregation of protofibrils.

  Journal of thrombosis and haemostasis : JTH 20050501

• [Enema therapy for ulcerative colitis patients].

  Nihon rinsho. Japanese journal of clinical medicine 20050501

• CYP3A43 Pro(340)Ala polymorphism and prostate cancer risk in African Americans and Caucasians.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050501

• Partial redirection of transgenic human growth hormone secretion from rat salivary glands.

  Human gene therapy 20050501

• Effects of Ser2 and Tyr6 mutants of BAF53 on cell growth and p53-dependent transcription.

  Molecules and cells 20050430

• An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor.

  The Journal of biological chemistry 20050429

• Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin.

  The Journal of biological chemistry 20050429

• The A140V mutation in the MECP2 gene is not a common etiological factor among Brazilian mentally retarded males.

  Neuroscience letters 20050429

• NMR study of the adsorption-desorption kinetics of dissolved tetraalanine in MCM-41 mesoporous material.

  The journal of physical chemistry. B 20050428

• Protein kinase A mediates regulation of gap junctions containing connexin35 through a complex pathway.

  Brain research. Molecular brain research 20050427

• Functional regulation of Na+-dependent neutral amino acid transporter ASCT2 by S-nitrosothiols and nitric oxide in Caco-2 cells.

  FEBS letters 20050425

• Global transcriptional programs reveal a carbon source foraging strategy by Escherichia coli.

  The Journal of biological chemistry 20050422

• Two-dimensional infrared spectroscopy of the alanine dipeptide in aqueous solution.

  The journal of physical chemistry. B 20050421

• Residues stabilizing the heme moiety of the nitric oxide sensor soluble guanylate cyclase.

  European journal of pharmacology 20050418

• Peptidase activity of the Escherichia coli Hsp31 chaperone.

  The Journal of biological chemistry 20050415

• The human TREX2 3' -> 5'-exonuclease structure suggests a mechanism for efficient nonprocessive DNA catalysis.

  The Journal of biological chemistry 20050415

• Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste.

  The Journal of biological chemistry 20050415

• Regulation of biological activity and matrix assembly of laminin-5 by COOH-terminal, LG4-5 domain of alpha3 chain.

  The Journal of biological chemistry 20050415

• Two regions in the N-terminal domain of ionotropic glutamate receptor 3 form the subunit oligomerization interfaces that control subtype-specific receptor assembly.

  The Journal of biological chemistry 20050415

• Expression, localization, structural, and functional characterization of pFGE, the paralog of the Calpha-formylglycine-generating enzyme.

  The Journal of biological chemistry 20050415

• Mechanism of the Norrish-Yang photocyclization reaction of an alanine derivative in the singlet state: origin of the chiral-memory effect.

  Angewandte Chemie (International ed. in English) 20050415

• Protein linear indices of the 'macromolecular pseudograph alpha-carbon atom adjacency matrix' in bioinformatics. Part 1: prediction of protein stability effects of a complete set of alanine substitutions in Arc repressor.

  Bioorganic & medicinal chemistry 20050415

• The unexpected structural role of glutamate synthase [4Fe-4S](+1,+2) clusters as demonstrated by site-directed mutagenesis of conserved C residues at the N-terminus of the enzyme beta subunit.

  Archives of biochemistry and biophysics 20050415

• Synthesis of a C20-C26 segment of superstolide A by addition of a chiral allenylzinc reagent to (R)-N-boc alaninal.

  Organic letters 20050414

• Automatic method for identifying reaction coordinates in complex systems.

  The journal of physical chemistry. B 20050414

• Dynamics of amide-I modes of the alanine dipeptide in D2O.

  The journal of physical chemistry. B 20050414

• Regulation of Ca2+-dependent desensitization in the vanilloid receptor TRPV1 by calcineurin and cAMP-dependent protein kinase.

  The Journal of biological chemistry 20050408

• Optimized DNA targeting using N,N-bis(2-pyridylmethyl)-beta-alanyl 2'-amino-LNA.

  Chemical communications (Cambridge, England) 20050407

• From 1-acyl-beta-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors.

  Journal of medicinal chemistry 20050407

• Sequence-selective recognition of peptides within the single binding pocket of a self-assembled coordination cage.

  Journal of the American Chemical Society 20050406

• Entropic stabilization of isolated beta-sheets.

  Journal of the American Chemical Society 20050406

• Folding and binding integrity of variants of a prototype ligand-binding module from the LDL receptor possessing multiple alanine substitutions.

  Biochemistry 20050405

• Nucleotide specificity of HIV-1 reverse transcriptases with amino acid substitutions affecting Ala-114.

  The Biochemical journal 20050401

• Alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis. Mutational and structural characterization of the active site and the fold.

  The Journal of biological chemistry 20050401

• Energetics of proton transfer pathways in reaction centers from Rhodobacter sphaeroides. The Glu-H173 activated mutants.

  The Journal of biological chemistry 20050401

• Structural locus of the pH gate in the Kir1.1 inward rectifier channel.

  Biophysical journal 20050401

• Monte Carlo studies of folding, dynamics, and stability in alpha-helices.

  Biophysical journal 20050401

• Structure-guided mutational analysis of the nucleotidyltransferase domain of Escherichia coli NAD+-dependent DNA ligase (LigA).

  The Journal of biological chemistry 20050401

• Phosphorylation-dependent binding of 14-3-3 to Par3beta, a human Par3-related cell polarity protein.

  Biochemical and biophysical research communications 20050401

• Melatonin-induced modulation of glucose metabolism in primary cultures of rabbit kidney-cortex tubules.

  Journal of pineal research 20050401

• Solvatochromism of 3-[2-(4-diphenylaminophenyl)benzoxazol-5-yl]alanine methyl ester. A new fluorescence probe.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050401

• Delineation of the minimal encephalitogenic epitope of proteolipid protein peptide(91-110) and critical residues required for induction of EAE in HLA-DR3 transgenic mice.

  Journal of neuroimmunology 20050401

• Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein.

  Experimental neurology 20050401

• Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease.

  Neurobiology of disease 20050401

• Accumulation of human SOD1 and ubiquitinated deposits in the spinal cord of SOD1G93A mice during motor neuron disease progression correlates with a decrease of proteasome.

  Neurobiology of disease 20050401

• Effect of hyper or hypo-osmotic conditions on neutral amino acid uptake and oxidation in tissues of the crab Chasmagnathus granulata.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050401

• Triple-quantum dynamics in multiple-spin systems undergoing magic-angle spinning: application to 13C homonuclear correlation spectroscopy.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20050401

• Orthogonally protected lanthionines: synthesis and use for the solid-phase synthesis of an analogue of nisin ring C.

  The Journal of organic chemistry 20050401

• An autosomal recessive limb girdle muscular dystrophy (LGMD2) with mild mental retardation is allelic to Walker-Warburg syndrome (WWS) caused by a mutation in the POMT1 gene.

  Neuromuscular disorders : NMD 20050401

• A novel ANT1 gene mutation with probable germline mosaicism in autosomal dominant progressive external ophthalmoplegia.

  Neuromuscular disorders : NMD 20050401

• Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP.

  The FEBS journal 20050401

• Metabolism of amino acids by cultured rat Sertoli cells.

  Metabolism: clinical and experimental 20050401

• Structure of a pseudomerohedrally twinned monoclinic crystal form of a pyridoxal phosphate-dependent catalytic antibody.

  Acta crystallographica. Section D, Biological crystallography 20050401

• Substitution of the cysteine 438 residue in the cytoplasmic tail of the glucagon-like peptide-1 receptor alters signal transduction activity.

  The Journal of endocrinology 20050401

• Computationally designed variants of Escherichia coli chorismate mutase show altered catalytic activity.

  Protein engineering, design & selection : PEDS 20050401

• Presence of alanine-to-valine substitutions in myofibrillogenesis regulator 1 in paroxysmal nonkinesigenic dyskinesia: confirmation in 2 kindreds.

  Archives of neurology 20050401

• Alanine-scanning mutagenesis of HM-1 killer toxin and the essential residues for killing activity.

  Journal of biochemistry 20050401

• Is the Val16Ala manganese superoxide dismutase polymorphism associated with the aging process?

  The journals of gerontology. Series A, Biological sciences and medical sciences 20050401

• Glutathionylation of lens proteins through the formation of thioether bond.

  Molecular and cellular biochemistry 20050401

• Enantiomeric excess of amino acids in hydrothermal environments.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20050401

• Correlations among morphology, beta-sheet stability, and molecular structure in prion peptide aggregates.

  Biochemistry 20050329

• Effect of added nucleophilic species on the rate of primary amino acid nitrosation.

  Journal of the American Chemical Society 20050323

• ADAM33 enzyme properties and substrate specificity.

  Biochemistry 20050322

• Serine 16 phosphorylation induces an order-to-disorder transition in monomeric phospholamban.

  Biochemistry 20050322

• A mutant of eukaryotic protein synthesis initiation factor eIF4E(K119A) has an increased binding affinity for both m7G cap analogues and eIF4G peptides.

  Biochemistry 20050322

• The structure of the O-polysaccharide from the lipopolysaccharide of Providencia stuartii O57 containing an amide of D-galacturonic acid with L-alanine.

  Carbohydrate research 20050321

• Heterogeneous assembly of silver(I) and calcium(II) ions accompanying a dimer formation of cyclo(L-Ala-L-Met)3.

  Chemical communications (Cambridge, England) 20050321

• Ir-192 HDR transit dose and radial dose function determination using alanine/EPR dosimetry.

  Physics in medicine and biology 20050321

• An experimental and Monte Carlo investigation of the energy dependence of alanine/EPR dosimetry: II. Clinical electron beams.

  Physics in medicine and biology 20050321

• Interaction between the catalytic site and the A-M3 linker stabilizes E2/E2P conformational states of Na+,K+-ATPase.

  The Journal of biological chemistry 20050318

• Cellular stability of serotonin N-acetyltransferase conferred by phosphonodifluoromethylene alanine (Pfa) substitution for Ser-205.

  The Journal of biological chemistry 20050318

• Reaction of morphinone reductase with 2-cyclohexen-1-one and 1-nitrocyclohexene: proton donation, ligand binding, and the role of residues Histidine 186 and Asparagine 189.

  The Journal of biological chemistry 20050318

• DNA binding of repressor nuclear factor-kappaB p50/p50 depends on phosphorylation of Ser337 by the protein kinase A catalytic subunit.

  The Journal of biological chemistry 20050318

• MEIS C termini harbor transcriptional activation domains that respond to cell signaling.

  The Journal of biological chemistry 20050318

• Crystal structure of S-ribosylhomocysteinase (LuxS) in complex with a catalytic 2-ketone intermediate.

  Biochemistry 20050315

• P450 active site architecture and reversibility: inactivation of cytochromes P450 2B4 and 2B4 T302A by tert-butyl acetylenes.

  Biochemistry 20050315

• Probing the oligomeric state of phospholamban variants in phospholipid bilayers from solid-state NMR measurements of rotational diffusion rates.

  Biochemistry 20050315

• A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad.

  Biochemistry 20050315

• Membrane transport proteins with complete replacement of transmembrane helices with polyalanine sequences remain functional.

  The Journal of biological chemistry 20050311

• Comparative density-functional study of the electron paramagnetic resonance parameters of amavadin.

  The journal of physical chemistry. B 20050310

• A receptor domain controls the intracellular sorting of the ferrichrome transporter, ARN1.

  The EMBO journal 20050309

• Base selectivity is impaired by mutants that perturb hydrogen bonding networks in the RB69 DNA polymerase active site.

  Biochemistry 20050308

• Denaturant-assisted formation of a stabilizing disulfide bridge from engineered cysteines in nonideal conformations.

  Biochemistry 20050308

• The factor IXa heparin-binding exosite is a cofactor interactive site: mechanism for antithrombin-independent inhibition of intrinsic tenase by heparin.

  Biochemistry 20050308

• Pharmacology of GABAC receptors: responses to agonists and antagonists distinguish A- and B-subtypes of homomeric rho receptors expressed in Xenopus oocytes.

  Neuroscience letters 20050307

• Single amino acid mutations in the cadherin receptor from Heliothis virescens affect its toxin binding ability to Cry1A toxins.

  The Journal of biological chemistry 20050304

• Thrombomodulin changes the molecular surface of interaction and the rate of complex formation between thrombin and protein C.

  The Journal of biological chemistry 20050304

• The nociceptin pharmacophore site for opioid receptor binding derived from the NMR structure and bioactivity relationships.

  The Journal of biological chemistry 20050304

• Side chain orientation of residues lining the selectivity filter of epithelial Na+ channels.

  The Journal of biological chemistry 20050304

• Residues within the first subdomain of the FERM-like domain in focal adhesion kinase are important in its regulation.

  The Journal of biological chemistry 20050304

• Two heme binding sites are involved in the regulated degradation of the bacterial iron response regulator (Irr) protein.

  The Journal of biological chemistry 20050304

• The E46K mutation in alpha-synuclein increases amyloid fibril formation.

  The Journal of biological chemistry 20050304

• Glycine-induced neurotoxicity in organotypic hippocampal slice cultures.

  Experimental brain research 20050301

• Arg333 and Arg334 in the COOH terminus of the human P2Y1 receptor are crucial for Gq coupling.

  American journal of physiology. Cell physiology 20050301

• Hepatic glycogen breakdown is implicated in the maintenance of plasma mannose concentration.

  American journal of physiology. Endocrinology and metabolism 20050301

• The PPAR{gamma} Pro12Ala polymorphism and risk for incident sporadic colorectal adenomas.

  Carcinogenesis 20050301

• Association of Ala72Ser polymorphism with COMT enzyme activity and the risk of schizophrenia in Koreans.

  Human genetics 20050301

• Importance of the central region of lamprey gonadotropin-releasing hormone III in the inhibition of breast cancer cell growth.

  Peptides 20050301

• Understanding the energetics of helical peptide orientation in membranes.

  Proteins 20050301

• Catalytic and structural characteristics of carp hepatopancreas D-amino acid oxidase expressed in Escherichia coli.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050301

• Design, development and synthesis of mixed bioconjugates of piperic acid-glycine, curcumin-glycine/alanine and curcumin-glycine-piperic acid and their antibacterial and antifungal properties.

  Bioorganic & medicinal chemistry 20050301

• Endurance exercise training in orthostatic intolerance: a randomized, controlled trial.

  Hypertension (Dallas, Tex. : 1979) 20050301

• Phosphoregulation of Arp2/3-dependent actin assembly during receptor-mediated endocytosis.

  Nature cell biology 20050301

• The frequency of limb girdle muscular dystrophy 2A in northeastern Italy.

  Neuromuscular disorders : NMD 20050301

• Regulated folding of tyrosinase in the endoplasmic reticulum demonstrates that misfolded full-length proteins are efficient substrates for class I processing and presentation.

  Journal of immunology (Baltimore, Md. : 1950) 20050301

• Are plasma total homocysteine and other amino acids associated with glucose intolerance in uncomplicated pregnancies and preeclampsia?

  European journal of obstetrics, gynecology, and reproductive biology 20050301

• Abrogation of fibroblast activation protein enzymatic activity attenuates tumor growth.

  Molecular cancer therapeutics 20050301

• Functional implications of modifying RyR-activating peptides for membrane permeability.

  British journal of pharmacology 20050301

• Structure-activity relationships of arodyn, a novel acetylated kappa opioid receptor antagonist.

  The journal of peptide research : official journal of the American Peptide Society 20050301

• [Anti-oxidative effect of ribonuclease inhibitor by site-directed mutagenesis and expression in Pichia pastoris].

  Yi chuan = Hereditas 20050301

• MTAP homozygous deletion: an Achilles heel of human cancers ready for clinical use?

  Cancer biology & therapy 20050301

• [Studies on the germination of Bacillus anthracoides spores induced by nutrient germinant].

  Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20050301

• Characterization of strychnine-sensitive glycine receptor in the intact frog retina: modulation by protein kinases.

  Neurochemical research 20050301

• Synthesis of amino acid-based polymers via atom transfer radical polymerization in aqueous media at ambient temperature.

  Chemical communications (Cambridge, England) 20050227

• Regulation of the transcription factor, CTCF, by phosphorylation with protein kinase CK2.

  FEBS letters 20050227

• Pore-to-gate coupling of HCN channels revealed by a pore variant that contributes to gating but not permeation.

  Biochemical and biophysical research communications 20050225

• Theoretical study of the electronic gas-phase spectrum of glycine, alanine, and related amines and carboxylic acids.

  The journal of physical chemistry. A 20050224

• Comparative study of generalized born models: Born radii and peptide folding.

  The journal of physical chemistry. B 20050224

• Evidence for retro-translocation of pokeweed antiviral protein from endoplasmic reticulum into cytosol and separation of its activity on ribosomes from its activity on capped RNA.

  Biochemistry 20050222

• Investigation of the functional contributions of invariant serine residues in yeast mevalonate diphosphate decarboxylase.

  Biochemistry 20050222

• Contribution of transmembrane regions to ATP-gated P2X2 channel permeability dynamics.

  The Journal of biological chemistry 20050218

• Regulation of nif expression in Methanococcus maripaludis: roles of the euryarchaeal repressor NrpR, 2-oxoglutarate, and two operators.

  The Journal of biological chemistry 20050218

• Thiazolylalanine-derived catalysts for enantioselective intermolecular aldehyde-imine cross-couplings.

  Journal of the American Chemical Society 20050216

• Proteinase-activated receptors (PARs)--the PAR3 Neo-N-terminal peptide TFRGAP interacts with PAR1.

  Regulatory peptides 20050215

• Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase.

  Biochemistry 20050215

• Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: structural basis for catalytic promiscuity in wild-type and designed mutants of 3-keto-L-gulonate 6-phosphate decarboxylase.

  Biochemistry 20050215

• Understanding GFP chromophore biosynthesis: controlling backbone cyclization and modifying post-translational chemistry.

  Biochemistry 20050215

• Probing the environment of signal-anchor sequences during topogenesis in the endoplasmic reticulum.

  Biochemistry 20050215

• Membrane-bound pyrophosphatase of Thermotoga maritima requires sodium for activity.

  Biochemistry 20050215

• Induced fit of an epitope peptide to a monoclonal antibody probed with a novel parallel surface plasmon resonance assay.

  The Journal of biological chemistry 20050211

• Phosphorylation-independent beta-arrestin translocation and internalization of leukotriene B4 receptors.

  The Journal of biological chemistry 20050211

• Cysteine-scanning mutagenesis of muscle carnitine palmitoyltransferase I reveals a single cysteine residue (Cys-305) is important for catalysis.

  The Journal of biological chemistry 20050211

• A region in the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+.

  The Journal of biological chemistry 20050211

• Shape-specific nucleotide binding of single-stranded RNA by the GLD-1 STAR domain.

  Journal of molecular biology 20050211

• Detection of intermediates from the polymerization reaction catalyzed by a D302A mutant of class III polyhydroxyalkanoate (PHA) synthase.

  Biochemistry 20050208

• Augmenter of liver regeneration: a flavin-dependent sulfhydryl oxidase with cytochrome c reductase activity.

  Biochemistry 20050208

• A spider toxin that induces a typical effect of scorpion alpha-toxins but competes with beta-toxins on binding to insect sodium channels.

  Biochemistry 20050208

• Probing the communication between the regulatory and catalytic domains of a protein tyrosine kinase, Csk.

  Biochemistry 20050208

• The contribution of C alpha-H...O hydrogen bonds to membrane protein stability depends on the position of the amide.

  Biochemistry 20050208

• Characterization of the mutant (A115V) tissue-nonspecific alkaline phosphatase gene from adult-type hypophosphatasia.

  Biochemical and biophysical research communications 20050204

• Identification of amino acids important for target recognition by the DNA:m5C methyltransferase M.NgoPII by alanine-scanning mutagenesis of residues at the protein-DNA interface.

  Proteins 20050201

• In vitro analysis of partial loss-of-function ZIC2 mutations in holoprosencephaly: alanine tract expansion modulates DNA binding and transactivation.

  Human molecular genetics 20050201

• Electron spin relaxation times for the alanine radical in two dosimeters.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20050201

• Use of alanine for dosimetry intercomparisons among Italian radiotherapy centers.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20050201

• K-band EPR dosimetry: small-field beam profile determination with miniature alanine dosimeter.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20050201

• Analysis of parameters that influence the amplitude of the ESR/alanine signal after irradiation.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20050201

• Use of the entire spectrum of irradiated alanine for dosimetry.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20050201

• ESR dosimetric properties of some biomineral materials.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20050201

• bac genes for recombinant bacilysin and anticapsin production in Bacillus host strains.

  Archives of microbiology 20050201

• Bacterial lantibiotics: strategies to improve therapeutic potential.

  Current protein & peptide science 20050201

• A single nucleotide polymorphism on the promoter of eotaxin1 associates with its mRNA expression and asthma phenotypes.

  Journal of immunology (Baltimore, Md. : 1950) 20050201

• Peroxisome proliferator-activated receptor-gamma2 Pro12Ala and endothelial nitric oxide synthase-4a/b gene polymorphisms are not associated with hypertension in diabetes mellitus type 2.

  Journal of hypertension 20050201

• Pivotal role of the glycine-rich TM3 helix in gating the MscS mechanosensitive channel.

  Nature structural & molecular biology 20050201

• Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II.

  Biochemistry 20050201

• Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway.

  Biochemistry 20050201

• Tryptophan residues flanking the second transmembrane helix (TM2) set the signaling state of the Tar chemoreceptor.

  Biochemistry 20050201

• Identification of residues that contribute to receptor activation through the analysis of compensatory mutations in the G protein-coupled alpha-factor receptor.

  Biochemistry 20050201

• The effective molarity of the substrate phosphoryl group in the transition state for yeast OMP decarboxylase.

  Bioorganic chemistry 20050201

• Metabolite profile of cerebrospinal fluid in patients with spina bifida: a proton magnetic resonance spectroscopy study.

  Spine 20050201

• Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant.

  Gastroenterology 20050201

• Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting.

  Structure (London, England : 1993) 20050201

• Structural plasticity in MS channels.

  Nature structural & molecular biology 20050201

• Synthesis and biological activity of GnRH antagonists modified at position 3 with 3-(2-methoxy-5-pyridyl)-alanine.

  The journal of peptide research : official journal of the American Peptide Society 20050201

• Pharmacokinetics of panipenem/betamipron in patients with end-stage renal disease.

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20050201

• The relationship between changes in serum glycine and alanine concentrations in non-essential amino acid and milk production in the transition period in dairy cows.

  The Journal of veterinary medical science 20050201

• Association of micropenis with Pro185Ala polymorphism of the gene for aryl hydrocarbon receptor repressor involved in dioxin signaling.

  Endocrine journal 20050201

• [PPARgamma gene Pro12Ala polymorphism in diabetes mellitus].

  Nihon rinsho. Japanese journal of clinical medicine 20050201

• [Fatty acid binding protein-2 (FABP2) gene polymorphism in diabetes].

  Nihon rinsho. Japanese journal of clinical medicine 20050201

• Assessing the cellular transmembrane electrical potential difference on the hepatic uptake of palmitate.

  Molecular and cellular biochemistry 20050201

• Early cardiac catheterization is associated with lower mortality only among high-risk patients with ST- and non-ST-elevation acute coronary syndromes: observations from the OPUS-TIMI 16 trial.

  American heart journal 20050201

• Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair in yeast.

  The Journal of biological chemistry 20050128

• A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization.

  The Journal of biological chemistry 20050128

• Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131.

  Journal of medicinal chemistry 20050127

• Structural changes of D1 C-terminal alpha-carboxylate during S-state cycling in photosynthetic oxygen evolution.

  The Journal of biological chemistry 20050121

• Consecutive elongation of alanine oligopeptides at the second time range under hydrothermal conditions using a microflow reactor system.

  Journal of the American Chemical Society 20050119

• The phosphatidylserine binding site of the factor Va C2 domain accounts for membrane binding but does not contribute to the assembly or activity of a human factor Xa-factor Va complex.

  Biochemistry 20050118

• A Gly/Ala switch contributes to high affinity binding of benzoxazinone-based non-peptide oxytocin receptor antagonists.

  FEBS letters 20050117

• A charged amino acid residue in the transmembrane/cytoplasmic region of tapasin influences MHC class I assembly and maturation.

  Journal of immunology (Baltimore, Md. : 1950) 20050115

• Identification of residues important for DNA binding in the full-length human Rad52 protein.

  Journal of molecular biology 20050114

• A peptide-catalyzed asymmetric Stetter reaction.

  Chemical communications (Cambridge, England) 20050114

• Coulomb-assisted dissociative electron attachment: application to a model peptide.

  The journal of physical chemistry. A 20050113

• Appearance and disappearance of dendritic and chiral patterns in domains of Langmuir monolayers observed with Brewster angle microscopy.

  The journal of physical chemistry. B 20050113

• The C-terminal residues in the alpha-interacting domain (AID) helix anchor CaV beta subunit interaction and modulation of CaV2.3 channels.

  The Journal of biological chemistry 20050107

• A primer-dependent polymerase function of pseudomonas aeruginosa ATP-dependent DNA ligase (LigD).

  The Journal of biological chemistry 20050107

• Glutamine kinetics and protein turnover in end-stage renal disease.

  American journal of physiology. Endocrinology and metabolism 20050101

• CYP1A1 variants and smoking-related lung cancer in San Francisco Bay area Latinos and African Americans.

  International journal of cancer 20050101

• Molecular dynamics simulation of transmembrane polypeptide orientational fluctuations.

  Biophysical journal 20050101

• Structural determinants for g protein activation and selectivity in the second intracellular loop of the thyrotropin receptor.

  Endocrinology 20050101

• Change in enantioselectivity in bufuralol 1''-hydroxylation by the substitution of phenylalanine-120 by alanine in cytochrome P450 2D6.

  Chirality 20050101

• PPAR-gamma2 Pro12Ala variant is associated with greater insulin sensitivity in childhood obesity.

  Pediatric research 20050101

• Phosphorylation of Cdc25C by pp90Rsk contributes to a G2 cell cycle arrest in Xenopus cycling egg extracts.

  Cell cycle (Georgetown, Tex.) 20050101

• Comparative acute effects of leptin and insulin on gluconeogenesis and ketogenesis in perfused rat liver.

  Cell biochemistry and function 20050101

• Activity of the lactate-alanine shuttle is independent of glutamate-glutamine cycle activity in cerebellar neuronal-astrocytic cultures.

  Journal of neuroscience research 20050101

• Zinc hydrolases: the mechanisms of zinc-dependent deacetylases.

  Archives of biochemistry and biophysics 20050101

• Redox regulation and reaction mechanism of human cystathionine-beta-synthase: a PLP-dependent hemesensor protein.

  Archives of biochemistry and biophysics 20050101

• Exacerbated synucleinopathy in mice expressing A53T SNCA on a Snca null background.

  Neurobiology of aging 20050101

• Substrate-trapping techniques in the identification of cellular PTP targets.

  Methods (San Diego, Calif.) 20050101

• Reversible assembly of helical filaments by de novo designed minimalist peptides.

  Biopolymers 20050101

• [Aladan3]TIPP: a fluorescent delta-opioid antagonist with high delta-receptor binding affinity and delta selectivity.

  Biopolymers 20050101

• Fuel utilization in subjects with carnitine palmitoyltransferase 2 gene mutations.

  Annals of neurology 20050101

• EvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environments.

  BMC bioinformatics 20050101

• Pharmacological characterization of ligand-receptor interactions at the zebrafish bradykinin receptor.

  British journal of pharmacology 20050101

• Enzymatic activity characterization of SARS coronavirus 3C-like protease by fluorescence resonance energy transfer technique.

  Acta pharmacologica Sinica 20050101

• The effects of alanine-substituted conantokin-G and ifenprodil on the human spermine-activated N-methyl-D-aspartate receptor.

  Neuroscience 20050101

• Renin-angiotensin system and haemostasis gene polymorphisms and outcome after coronary artery bypass graft surgery.

  International journal of cardiology 20050101

• [Detection of amino acid neurotransmitters in cerebrospinal fluid of patients in persistent vegetative state].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050101

• Identification of Fmoc-beta-Ala-OH and Fmoc-beta-Ala-amino acid-OH as new impurities in Fmoc-protected amino acid derivatives.

  The journal of peptide research : official journal of the American Peptide Society 20050101

• A practical synthesis of Nalpha-Fmoc-L-pyrazinylalanine via Schöllkopf's chiral auxiliary.

  The journal of peptide research : official journal of the American Peptide Society 20050101

• [Angiotensin converting enzyme, NO-synthase, and endothelin-1 genes and left ventricular hypertrophy in natives of Yakutia with hypertensive disease].

  Kardiologiia 20050101

• Leptin secretion and protein kinase A activity.

  Physiological research 20050101

• A possible association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma2 gene with obesity in native Javanese in Indonesia.

  Diabetes/metabolism research and reviews 20050101

• Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic beta-cells.

  European journal of endocrinology 20050101

• [Dynamics and functions of exometabolites in the process of the growth of Escherichia coli M-17 periodical culture].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20050101

• Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-gamma coactivator-1 gene might be a risk factor for diabetic retinopathy in Slovene population (Caucasians) with type 2 diabetes and the Pro12Ala polymorphism of the PPARgamma gene is not.

  Diabetes/metabolism research and reviews 20050101

• Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population.

  BMC medical genetics 20050101

• Possible steps to the emergence of life: the [GADV]-protein world hypothesis.

  Chemical record (New York, N.Y.) 20050101

• Response properties of dorsal root reflexes in cutaneous C fibers before and after intradermal capsaicin injection in rats.

  Neuroscience 20050101

• Requirements for estrogen receptor alpha membrane localization and function.

  Steroids 20050101

• Conformational behavior of chemically reactive alanine-rich repetitive protein polymers.

  Biomacromolecules 20050101

• Fatty liver in obese children: prevalence and correlation with anthropometric measurements and hyperlipidemia.

  The Turkish journal of pediatrics 20050101

• No association between the ionotropic glutamate receptor kainate 3 gene ser310ala polymorphism and schizophrenia.

  Neuropsychobiology 20050101

• Solution structure of chi-conopeptide MrIA, a modulator of the human norepinephrine transporter.

  Biopolymers 20050101

• The African sharptooth catfish Clarias gariepinus can tolerate high levels of ammonia in its tissues and organs during four days of aerial exposure.

  Physiological and biochemical zoology : PBZ 20050101

• Safety, tolerability, and changes in amyloid beta concentrations after administration of a gamma-secretase inhibitor in volunteers.

  Clinical neuropharmacology 20050101

• Utilizing a D-amino acid as a drug carrier for antineoplastic nitrogen mustard groups.

  Drug delivery 20050101

• Gene transfer efficacies of novel cationic amphiphiles with alanine, beta-alanine, and serine headgroups: a structure-activity investigation.

  Bioconjugate chemistry 20050101

• Loop movement and catalysis in creatine kinase.

  IUBMB life 20050101

• Eutectic formation analysis of amino acid mixtures using molecular dynamics simulations.

  Biotechnology progress 20050101

• Differential roles of mGlu8 receptors in the regulation of glutamate and gamma-aminobutyric acid release at periaqueductal grey level.

  Neuropharmacology 20050101

• Substrate preference is altered by mutations in the fifth transmembrane domain of Ptr2p, the di/tri-peptide transporter of Saccharomyces cerevisiae.

  Molecular membrane biology 20050101

• Homozygosity at the C677T of the MTHFR gene is associated with increased breast cancer risk in the Turkish population.

  In vivo (Athens, Greece) 20050101

• 3-T proton magnetic resonance spectroscopy of central neurocytoma: 3 case reports and review of the literature.

  Journal of computer assisted tomography 20050101

• Effect of individual amino acids and glucose on activation and germination of Rhizopus oligosporus sporangiospores in tempe starter.

  Journal of applied microbiology 20050101

• Structure of model peptides based on Nephila clavipes dragline silk spidroin (MaSp1) studied by 13C cross polarization/magic angle spinning NMR.

  Biomacromolecules 20050101

• New aspects on the formation and analysis of acrylamide.

  Advances in experimental medicine and biology 20050101

• The influence of the Pro12Ala mutation of PPARgamma2 receptor gene on beta-cells restoration and insulin resistance in type 2 diabetes with hypertension.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101

• Scratching below the surface: wound healing and alanine mutagenesis provide unique insights into interactions between eristostatin, platelets and melanoma cells.

  Pathophysiology of haemostasis and thrombosis 20050101

• A simple approach to sense codon-templated synthesis of natural/unnatural hybrid peptides.

  Nucleic acids symposium series (2004) 20050101

• Dissection of antibacterial and toxic activity of melittin: a leucine zipper motif plays a crucial role in determining its hemolytic activity but not antibacterial activity.

  The Journal of biological chemistry 20041231

• Fas-associated protein with death domain (FADD)-independent recruitment of c-FLIPL to death receptor 5.

  The Journal of biological chemistry 20041231

• Many amino acid substitutions in a hypoxia-inducible transcription factor (HIF)-1alpha-like peptide cause only minor changes in its hydroxylation by the HIF prolyl 4-hydroxylases: substitution of 3,4-dehydroproline or azetidine-2-carboxylic acid for the proline leads to a high rate of uncoupled 2-oxoglutarate decarboxylation.

  The Journal of biological chemistry 20041231

• Nuclear localization destabilizes the stress-regulated transcription factor Msn2.

  The Journal of biological chemistry 20041231

• Protein quadratic indices of the 'macromolecular pseudograph's alpha-carbon atom adjacency matrix'. 1. Prediction of Arc repressor alanine-mutant's stability.

  Molecules (Basel, Switzerland) 20041231

• The mobile proton in polyalanine peptides.

  Journal of the American Chemical Society 20041229

• Investigations of polypeptide rotational diffusion in aligned membranes by 2H and 15N solid-state NMR spectroscopy.

  Journal of the American Chemical Society 20041222

• An application of coupled reference interaction site model/molecular dynamics to the conformational analysis of the alanine dipeptide.

  The Journal of chemical physics 20041222

• Substrate interaction at an iron-sulfur face of the FeMo-cofactor during nitrogenase catalysis.

  The Journal of biological chemistry 20041217

• Identification of negative residues in the P2X3 ATP receptor ectodomain as structural determinants for desensitization and the Ca2+-sensing modulatory sites.

  The Journal of biological chemistry 20041217

• Substrate specificity and kinetic mechanism of mammalian G9a histone H3 methyltransferase.

  The Journal of biological chemistry 20041217

• Ionic interactions near the loop L4 are important for maintaining the active-site environment and the dimer stability of (pro)caspase 3.

  The Biochemical journal 20041215

• Differential activation of ERK, p38, and JNK required for Th1 and Th2 deviation in myelin-reactive T cells induced by altered peptide ligand.

  Journal of immunology (Baltimore, Md. : 1950) 20041215

• Multivalency in supramolecular chemistry and nanofabrication.

  Organic & biomolecular chemistry 20041207

• The box VII motif of Escherichia coli DnaA protein is required for DnaA oligomerization at the E. coli replication origin.

  The Journal of biological chemistry 20041203

• A novel zinc finger structure in the large subunit of human general transcription factor TFIIE.

  The Journal of biological chemistry 20041203

• Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling.

  The Journal of biological chemistry 20041203

• Plasmodium vivax merozoite surface protein PvMSP-3 beta is radically polymorphic through mutation and large insertions and deletions.

  Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20041201

• Gliotoxins disrupt alanine metabolism and glutathione production in C6 glioma cells: a 13C NMR spectroscopic study.

  Neurochemistry international 20041201

• Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study.

  Arteriosclerosis, thrombosis, and vascular biology 20041201

• Influence of phenylalanine 120 on cytochrome P450 2D6 catalytic selectivity and regiospecificity: crucial role in 7-methoxy-4-(aminomethyl)-coumarin metabolism.

  Biochemical pharmacology 20041201

• Effect of theophylline on L-alanine absorption in the rat jejunum.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20041201

• Marfey's reagent for chiral amino acid analysis: a review.

  Amino acids 20041201

• Role of hydrogen sulphide in haemorrhagic shock in the rat: protective effect of inhibitors of hydrogen sulphide biosynthesis.

  British journal of pharmacology 20041201

• No association of the A260G and A386G DAZL single nucleotide polymorphisms with male infertility in a Caucasian population.

  Human reproduction (Oxford, England) 20041201

• Stochastic Liouville equation simulation of multidimensional vibrational line shapes of trialanine.

  The Journal of chemical physics 20041201

• A novel mechanism for TNF-alpha regulation by p38 MAPK: involvement of NF-kappa B with implications for therapy in rheumatoid arthritis.

  Journal of immunology (Baltimore, Md. : 1950) 20041201

• Variant phenotypes of incomplete achromatopsia in two cousins with GNAT2 gene mutations.

  Investigative ophthalmology & visual science 20041201

• Exercise-induced changes in insulin and glucagon are not required for enhanced hepatic glucose uptake after exercise but influence the fate of glucose within the liver.

  Diabetes 20041201

• Nuclear import of the BTB/POZ transcriptional regulator Kaiso.

  Journal of cell science 20041201

• Stability and cleavage conditions of (2-furyl)-L-alanine-containing peptides.

  Protein and peptide letters 20041201

• Testicular dysgenesis without adrenal insufficiency in a 46,XY patient with a heterozygous inactive mutation of steroidogenic factor-1.

  The Journal of clinical endocrinology and metabolism 20041201

• Hypofibrinogenaemia associated with a novel heterozygous gamma289 Ala -->Val substitution (fibrinogen Dorfen).

  Thrombosis and haemostasis 20041201

• Fragmentation of protonated oligoalanines: amide bond cleavage and beyond.

  Journal of the American Society for Mass Spectrometry 20041201

• The Ala-9Val polymorphism in the mitochondrial targeting sequence (MTS) of the manganese superoxide dismutase gene is not associated with juvenile-onset asthma.

  Clinical biochemistry 20041201

• Saccharomyces cerevisiae Aqr1 is an internal-membrane transporter involved in excretion of amino acids.

  Eukaryotic cell 20041201

• A recurrent polyalanine expansion in the transcription factor FOXL2 induces extensive nuclear and cytoplasmic protein aggregation.

  Journal of medical genetics 20041201

• Effects of long-term intravenous and intragastric L-arginine intervention on jejunal motility and visceral nitric oxide production in the hyperdynamic compensated endotoxaemic pig.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20041201

• Ethnic origin determines the impact of genetic variants in dopamine receptor gene (DRD1) concerning essential hypertension.

  American journal of hypertension 20041201

• No evidence of a role for PPARgamma Pro12Ala polymorphism in endometrial cancer susceptibility.

  Pharmacogenetics 20041201

• Nutrients released by gastric epithelial cells enhance Helicobacter pylori growth.

  Helicobacter 20041201

• The effects of amino acid replacements of glycine 20 on conformational stability and catalysis of staphylococcal nuclease.

  Biochimie 20041201

• Relative carnitine deficiency in autism.

  Journal of autism and developmental disorders 20041201

• Establishment of native insulin-negative NOD mice and the methodology to distinguish specific insulin knockout genotypes and a B:16 alanine preproinsulin transgene.

  Annals of the New York Academy of Sciences 20041201

• Light-induced structural changes of LOV domain-containing polypeptides from Arabidopsis phototropin 1 and 2 studied by small-angle X-ray scattering.

  Biochemistry 20041130

• Strength of integration of transmembrane alpha-helical peptides in lipid bilayers as determined by atomic force spectroscopy.

  Biochemistry 20041130

• Pharmacological characterization of rebamipide: its cholecystokinin CCK1 receptor binding profile and effects on Ca2+ mobilization and amylase release in rat pancreatic acinar cells.

  European journal of pharmacology 20041128

• Effect of metal ion binding on the structural stability of the hepatitis C virus RNA polymerase.

  The Journal of biological chemistry 20041126

• Dipeptides as microporous materials.

  Angewandte Chemie (International ed. in English) 20041126

• The role of Ca2+-coordinating residues of herring antifreeze protein in antifreeze activity.

  Biochemistry 20041123

• Molecular functions of conserved aspects of the GHMP kinase family.

  Biochemistry 20041123

• Treatment of cells with the angiogenic inhibitor fumagillin results in increased stability of eukaryotic initiation factor 2-associated glycoprotein, p67, and reduced phosphorylation of extracellular signal-regulated kinases.

  Biochemistry 20041123

• Enzymatic resolution for the preparation of enantiomerically enriched D-beta-heterocyclic alanine derivatives using Escherichia coli aromatic L-amino acid transaminase.

  Biotechnology and bioengineering 20041120

• Amino acids of the Sulfolobus solfataricus mini-chromosome maintenance-like DNA helicase involved in DNA binding/remodeling.

  The Journal of biological chemistry 20041119

• A cloned prokaryotic Cd2+ P-type ATPase increases yeast sensitivity to Cd2+.

  Biochemical and biophysical research communications 20041119

• Computational and biochemical identification of a nuclear pore complex binding site on the nuclear transport carrier NTF2.

  Journal of molecular biology 20041119

• Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA).

  Journal of molecular biology 20041119

• Ycf1-dependent cadmium detoxification by yeast requires phosphorylation of residues Ser908 and Thr911.

  FEBS letters 20041119

• Probing the active site of homoserine trans-succinylase.

  FEBS letters 20041119

• Structural examination of phi-value analysis in protein folding.

  Biochemistry 20041116

• Role of lysine-256 in Citrobacter freundii tyrosine phenol-lyase in monovalent cation activation.

  Biochemistry 20041116

• Evolution of glutamate dehydrogenase regulation of insulin homeostasis is an example of molecular exaptation.

  Biochemistry 20041116

• Dioxygenases without requirement for cofactors and their chemical model reaction: compulsory order ternary complex mechanism of 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase involving general base catalysis by histidine 251 and single-electron oxidation of the substrate dianion.

  Biochemistry 20041116

• Two-dimensional IR correlation spectroscopy of mutants of the beta-glycosidase from the hyperthermophilic archaeon Sulfolobus solfataricus identifies the mechanism of quaternary structure stabilization and unravels the sequence of thermal unfolding events.

  The Biochemical journal 20041115

• Mutational analysis of histidine residues in human organic anion transporter 4 (hOAT4).

  The Biochemical journal 20041115

• Studies of SpoIIAB mutant proteins elucidate the mechanisms that regulate the developmental transcription factor sigmaF in Bacillus subtilis.

  The Biochemical journal 20041115

• Solvation effects on alanine dipeptide: A MP2/cc-pVTZ//MP2/6-31G** study of (Phi, Psi) energy maps and conformers in the gas phase, ether, and water.

  Journal of computational chemistry 20041115

• The coupling of structural fluctuations to hydride transfer in dihydrofolate reductase.

  Proteins 20041115

• Linear response theory: an alternative to PB and GB methods for the analysis of molecular dynamics trajectories?

  Proteins 20041115

• Cobalamin (vitamin B12) binding, phylogeny, and synteny of human transcobalamin.

  Archives of biochemistry and biophysics 20041115

• The critical role of the 185-189-loop in the factor Xa interaction with Na+ and factor Va in the prothrombinase complex.

  The Journal of biological chemistry 20041112

• Ex vivo analysis of lactate and glucose metabolism in the rat brain under different states of depressed activity.

  The Journal of biological chemistry 20041112

• A facile and efficient synthesis of (Purin-6-yl)alanines.

  The Journal of organic chemistry 20041112

• Familial Alzheimer disease associated with A713T mutation in APP.

  Neuroscience letters 20041111

• Strand orientation by steric matching: a designed antiparallel coiled-coil trimer.

  Journal of the American Chemical Society 20041110

• Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant.

  Biochemistry 20041109

• A piezoelectric quartz crystal biosensor: the use of two single cysteine mutants of the periplasmic Escherichia coli glucose/galactose receptor as target proteins for the detection of glucose.

  Biochemistry 20041109

• Properties of P-glycoprotein with mutations in the 'catalytic carboxylate' glutamate residues.

  The Journal of biological chemistry 20041105

• C-Terminal 23 kDa polypeptide of soybean Gly m Bd 28 K is a potential allergen.

  Planta 20041101

• A common antitussive drug, clobutinol, precipitates the long QT syndrome 2.

  Molecular pharmacology 20041101

• Molecular determinants of frequency dependence and Ca2+ potentiation of verapamil block in the pore region of Cav1.2.

  Molecular pharmacology 20041101

• Photophysical processes of a fluorene derivative containing 1,3,4-oxadiazole.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20041101

• Unexpected intracellular localization of the AMD-associated cystatin C variant.

  Traffic (Copenhagen, Denmark) 20041101

• Hyperlactatemia in human immunodeficiency virus-uninfected infants who are exposed to antiretrovirals.

  Pediatrics 20041101

• Conformational restraints and flexibility of 14-meric peptides in complex with HLA-B*3501.

  Journal of immunology (Baltimore, Md. : 1950) 20041101

• Characterization of hemoglobin bassett (alpha94Asp-->Ala), a variant with very low oxygen affinity.

  American journal of hematology 20041101

• The PRC-barrel domain of the ribosome maturation protein RimM mediates binding to ribosomal protein S19 in the 30S ribosomal subunits.

  RNA (New York, N.Y.) 20041101

• Identification of a peptide binding motif for secreted frizzled-related protein-1.

  Peptides 20041101

• ACAP1 promotes endocytic recycling by recognizing recycling sorting signals.

  Developmental cell 20041101

• Gender dependent association of thrombospondin-4 A387P polymorphism with myocardial infarction.

  Arteriosclerosis, thrombosis, and vascular biology 20041101

• Lattice corneal dystrophy associated with the Ala546Asp and Pro551Gln missense changes in the TGFBI gene.

  American journal of ophthalmology 20041101

• The Arg64 allele of the beta 3-adrenoceptor gene but not the -3826G allele of the uncoupling protein 1 gene is associated with increased leptin levels in the Spanish population.

  Metabolism: clinical and experimental 20041101

• Planotetraspora silvatica sp. nov. and emended description of the genus Planotetraspora.

  International journal of systematic and evolutionary microbiology 20041101

• Alcohol increases glucagon secretion in normal man.

  Alcoholism, clinical and experimental research 20041101

• Behavioral comparisons of the tastes of L-alanine and monosodium glutamate in rats.

  Chemical senses 20041101

• Expression and cytotoxicity of EGFP-labeled D-amino acid oxidase in HeLa cells.

  Yi chuan xue bao = Acta genetica Sinica 20041101

• A male twin infant with skull deformity and elevated neonatal 17-hydroxyprogesterone: a prismatic case of P450 oxidoreductase deficiency.

  Endocrine research 20041101

• A mixed design reveals that glucose moieties facilitate extinction of a conditioned taste aversion in rats.

  Learning & behavior 20041101

• The helical alanine controversy: an (Ala)6 insertion dramatically increases helicity.

  Journal of the American Chemical Society 20041027

• The vaccinia virus B1R kinase induces p53 downregulation by an Mdm2-dependent mechanism.

  Virology 20041025

• Functional dissection and molecular characterization of calcium-sensitive actin-capping and actin-depolymerizing sites in villin.

  The Journal of biological chemistry 20041022

• The cysteine-rich region of T1R3 determines responses to intensely sweet proteins.

  The Journal of biological chemistry 20041022

• Regulating the balance between peroxisome proliferator-activated receptor gamma and beta-catenin signaling during adipogenesis. A glycogen synthase kinase 3beta phosphorylation-defective mutant of beta-catenin inhibits expression of a subset of adipogenic genes.

  The Journal of biological chemistry 20041022

• Characteristic recognition of N-acetylgalactosamine by an invertebrate C-type Lectin, CEL-I, revealed by X-ray crystallographic analysis.

  The Journal of biological chemistry 20041022

• Stabilization of alanine substituted p53 protein at Ser15, Thr18, and Ser20 in response to ionizing radiation.

  Biochemical and biophysical research communications 20041022

• Exploiting the right side of the Ramachandran plot: substitution of glycines by D-alanine can significantly increase protein stability.

  Journal of the American Chemical Society 20041020

• Mutation effects of a conserved alanine (Ala510) in type I polyhydroxyalkanoate synthase from Ralstonia eutropha on polyester biosynthesis.

  Macromolecular bioscience 20041020

• Alpha-tocopherol pro-vitamins: synthesis, hydrolysis and accumulation in rabbit ear skin.

  Journal of controlled release : official journal of the Controlled Release Society 20041019

• Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase.

  Biochemistry 20041019

• Rate-temperature relationships in lambda-repressor fragment lambda 6-85 folding.

  Biochemistry 20041019

• Mutational analysis of the nuclease domain of Escherichia coli ribonuclease III. Identification of conserved acidic residues that are important for catalytic function in vitro.

  Biochemistry 20041019

• The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1.

  The Journal of biological chemistry 20041015

• Thr(207) of claudin-5 is involved in size-selective loosening of the endothelial barrier by cyclic AMP.

  Experimental cell research 20041015

• Stereoselective synthesis of P-chiral phosphorus compounds from N-tert-butoxycarbonyl amino acids.

  The Journal of organic chemistry 20041015

• Amino acid backbone specificity of the Escherichia coli translation machinery.

  Journal of the American Chemical Society 20041013

• Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase.

  Biochemistry 20041012

• Dissecting the protein-protein interface between beta-lactamase inhibitory protein and class A beta-lactamases.

  The Journal of biological chemistry 20041008

• Molecular mapping of the thrombin-heparin cofactor II complex.

  The Journal of biological chemistry 20041008

• Monomeric analogues of halocidin.

  Organic & biomolecular chemistry 20041007

• A highly stable short alpha-helix constrained by a main-chain hydrogen-bond surrogate.

  Journal of the American Chemical Society 20041006

• Alpha-helical peptides are not protonated at the N-terminus in the gas phase.

  Journal of the American Chemical Society 20041006

• Long-range dynamic effects of point mutations propagate through side chains in the serine protease inhibitor eglin c.

  Biochemistry 20041005

• Cyanide binding to hexacoordinate cyanobacterial hemoglobins: hydrogen-bonding network and heme pocket rearrangement in ferric H117A Synechocystis hemoglobin.

  Biochemistry 20041005

• Mutation of the putative hydrogen-bond donor to P700 of photosystem I.

  Biochemistry 20041005

• Insulin secretion in lipodystrophic HIV-infected patients is associated with high levels of nonglucose secretagogues and insulin resistance of beta-cells.

  American journal of physiology. Endocrinology and metabolism 20041001

• FFAs are not involved in regulation of gluconeogenesis and glycogenolysis in adults with uncomplicated P. falciparum malaria.

  American journal of physiology. Endocrinology and metabolism 20041001

• Identification and characterization of the main beta-alanine uptake system in Escherichia coli.

  Applied microbiology and biotechnology 20041001

• Critical role of lysine 204 in switch I region of Galpha13 for regulation of p115RhoGEF and leukemia-associated RhoGEF.

  Molecular pharmacology 20041001

• Fast and accurate computation of the 13C chemical shifts for an alanine-rich peptide.

  Proteins 20041001

• Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation.

  Protein science : a publication of the Protein Society 20041001

• Antimicrobial activity of arginine- and tryptophan-rich hexapeptides: the effects of aromatic clusters, D-amino acid substitution and cyclization.

  The journal of peptide research : official journal of the American Peptide Society 20041001

• Density functional theory as a tool for the structure determination of radiation-induced bioradicals.

  Magnetic resonance in chemistry : MRC 20041001

• Dehydroalanine crosslinks in human lens.

  Experimental eye research 20041001

• Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS.

  Annals of neurology 20041001

• Comparative acute effects of l-carnitine and dl-carnitine on hepatic catabolism of l-alanine and l-glutamine in rats.

  Acta pharmacologica Sinica 20041001

• Stereoselectivity in the collision-activated reactions of gas phase salt complexes.

  Journal of the American Society for Mass Spectrometry 20041001

• New V272A presenilin 1 mutation with very early onset subcortical dementia and parkinsonism.

  European journal of neurology 20041001

• Association of male infertility with Pro185Ala polymorphism in the aryl hydrocarbon receptor repressor gene: implication for the susceptibility to dioxins.

  Fertility and sterility 20041001

• Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in alpha-tubulin.

  Molecular cancer therapeutics 20041001

• Novel peptide ligands for integrin alpha 4 beta 1 overexpressed in cancer cells.

  Molecular cancer therapeutics 20041001

• Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism.

  Seminars in oncology 20041001

• Metabolic effects of propofol in the isolated perfused rat liver.

  Basic & clinical pharmacology & toxicology 20041001

• Jak2 tyrosine kinase residues glutamic acid 1024 and arginine 1113 form a hydrogen bond interaction that is essential for Jak-STAT signal transduction.

  Molecular and cellular biochemistry 20041001

• The clinical impact of thiopurine methyltransferase polymorphisms on thiopurine treatment.

  Nucleosides, nucleotides & nucleic acids 20041001

• [Is obesity associated with a polymorphism Pro12Ala and Pro115Gln in the PPARgamma gene?].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20041001

• Changes in tissue protein synthesis are involved in regulating urea synthesis in rats given proteins of different quality.

  Journal of nutritional science and vitaminology 20041001

• Persistence and degradation of metalaxyl, mancozeb fungicides and its metabolite ethylenethiourea in soils.

  Journal of environmental science & engineering 20041001

• Interaction of a 43-kDa receptor-like protein with a 4-kDa hormone-like peptide in soybean.

  Biochemistry 20040928

• Dynamin GTPase domain mutants that differentially affect GTP binding, GTP hydrolysis, and clathrin-mediated endocytosis.

  The Journal of biological chemistry 20040924

• The fourth transmembrane domain of the Helicobacter pylori Na+/H+ antiporter NhaA faces a water-filled channel required for ion transport.

  The Journal of biological chemistry 20040924

• Serine and threonine phosphorylation of the low density lipoprotein receptor-related protein by protein kinase Calpha regulates endocytosis and association with adaptor molecules.

  The Journal of biological chemistry 20040924

• Autophosphorylation suppresses whereas kinase inhibition augments the translocation of protein kinase Calpha in response to diacylglycerol.

  The Journal of biological chemistry 20040924

• The COOH terminus of the amelogenin, LRAP, is oriented next to the hydroxyapatite surface.

  The Journal of biological chemistry 20040924

• Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents.

  Molecular cell 20040924

• The gas-phase structure of alanine.

  Journal of the American Chemical Society 20040922

• Synthesis of cinnamic acid derivatives and their inhibitory effects on LDL-oxidation, acyl-CoA:cholesterol acyltransferase-1 and -2 activity, and decrease of HDL-particle size.

  Bioorganic & medicinal chemistry letters 20040920

• The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.

  European journal of pharmacology 20040919

• Creation of a mouse expressing defective human factor IX.

  Blood 20040915

• Highly sensitive intramolecularly quenched fluorogenic substrates for renin based on the combination of L-2-amino-3-(7-methoxy-4-coumaryl)propionic acid with 2,4-dinitrophenyl groups at various positions.

  The Biochemical journal 20040915

• A91V is a polymorphism in the perforin gene not causative of an FHLH phenotype.

  Blood 20040915

• The -1438A/G polymorphism in the 5-hydroxytryptamine type 2A receptor gene affects promoter activity.

  Biological psychiatry 20040915

• Development of suppository formulation safely improving rectal absorption of rebamipide, a poorly absorbable drug, by utilizing sodium laurate and taurine.

  Journal of controlled release : official journal of the Controlled Release Society 20040914

• Expression of a nonpolymerizable actin mutant in Sf9 cells.

  Biochemistry 20040914

• Structural and functional interaction sites between Na,K-ATPase and FXYD proteins.

  The Journal of biological chemistry 20040910

• A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoid-inducible kinase consensus motif in the C terminus of the channel's alpha-subunit.

  The Journal of biological chemistry 20040910

• A functional aquaporin co-localizes with the vacuolar proton pyrophosphatase to acidocalcisomes and the contractile vacuole complex of Trypanosoma cruzi.

  The Journal of biological chemistry 20040910

• Overlapping binding sites in protein phosphatase 2A for association with regulatory A and alpha-4 (mTap42) subunits.

  The Journal of biological chemistry 20040910

• The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation.

  Journal of molecular biology 20040910

• Mycobacterium tuberculosis GroEL homologues unusually exist as lower oligomers and retain the ability to suppress aggregation of substrate proteins.

  Journal of molecular biology 20040910

• Interaction between matrix metalloproteinase 3 and the epsilon4 allele of apolipoprotein E increases the risk of Alzheimer's disease in Finns.

  Neuroscience letters 20040909

• Changes in dissolved organic carbon of soil amendments with aging: effect on pesticide adsorption behavior.

  Journal of agricultural and food chemistry 20040908

• Acetylcholine binding site in the vesicular acetylcholine transporter.

  Biochemistry 20040907

• Stereoselective synthesis and preliminary evaluation of new D-3-heteroarylcarbonylalanines as ligands of the NMDA receptor.

  Bioorganic & medicinal chemistry letters 20040906

• Solvation model induced structural changes in peptides. A quantum chemical study on Ramachandran surfaces and conformers of alanine diamide using the polarizable continuum model.

  Journal of computational chemistry 20040901

• Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040901

• Markovian Backbone Negentropies: Molecular descriptors for protein research. I. Predicting protein stability in Arc repressor mutants.

  Proteins 20040901

• A compensatory double mutation of the alanine-86 to leucine mutant located in the hinge region of the iron-sulfur protein of the yeast cytochrome bc1 complex.

  Archives of biochemistry and biophysics 20040901

• Neuronal accumulation of abnormal prion protein in sheep carrying a scrapie-resistant genotype (PrPARR/ARR).

  The Journal of general virology 20040901

• Epitope scanning reveals gain and loss of strain specific antibody binding epitopes associated with the conversion of normal cellular prion to scrapie prion.

  Journal of neurochemistry 20040901

• A BMAL1 mutant with arginine 91 substituted with alanine acts as a dominant negative inhibitor.

  Gene 20040901

• Hydrophobic core repacking in a coiled-coil dimer via phage display: insights into plasticity and specificity at a protein-protein interface.

  Journal of the American Chemical Society 20040901

• Claisen-type addition of glycine to pyridoxal in water.

  Journal of the American Chemical Society 20040901

• Presentation and detection of azide functionality in bacterial cell surface proteins.

  Journal of the American Chemical Society 20040901

• High incidence of type 2 diabetes in peroxisome proliferator-activated receptor gamma2 Pro12Ala carriers exposed to a high chronic intake of trans fatty acids and saturated fatty acids.

  Diabetes care 20040901

• PEN-2 enhances gamma-cleavage after presenilin heterodimer formation.

  Journal of neurochemistry 20040901

• In silico activation of KcsA K+ channel by lateral forces applied to the C-termini of inner helices.

  Biophysical journal 20040901

• Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri.

  Microbiology (Reading, England) 20040901

• Cell-surface alterations in class IIa bacteriocin-resistant Listeria monocytogenes strains.

  Microbiology (Reading, England) 20040901

• Ala12Ala genotype of the peroxisome proliferator-activated receptor gamma2 protects against atherosclerosis.

  The Journal of clinical endocrinology and metabolism 20040901

• The alpha-factor mating pheromone of Saccharomyces cerevisiae: a model for studying the interaction of peptide hormones and G protein-coupled receptors.

  Peptides 20040901

• Entropy considerations in kinetic method experiments.

  Journal of mass spectrometry : JMS 20040901

• Importance of the Sir3 N terminus and its acetylation for yeast transcriptional silencing.

  Genetics 20040901

• The discovery of alapyridaine, a new multimodal flavor enhancer.

  Molecular nutrition & food research 20040901

• Systematic studies of structure and physiological activity of alapyridaine. A novel food-born taste enhancer.

  Molecular nutrition & food research 20040901

• Oral absorption and pharmacokinetics of rebamipide and rebamipide lysinate in rats.

  Drug development and industrial pharmacy 20040901

• Stabilization of rasburicase and physico-chemical characterization of the resulting injectable formulation.

  Drug development and industrial pharmacy 20040901

• Mutational analysis of the helix-turn-helix region of Bacillus subtilis response regulator DegU, and identification of cis-acting sequences for DegU in the aprE and comK promoters.

  Journal of biochemistry 20040901

• Transfer of (15)N from oral lactose-ureide to lysine in normal adults.

  International journal of food sciences and nutrition 20040901

• Functional significance of the BBXXB motif reversed present in the cytoplasmic domains of the human follicle-stimulating hormone receptor.

  Molecular and cellular endocrinology 20040831

• Segregation pattern and biochemical effect of the G3460A mtDNA mutation in 27 members of LHON family.

  Journal of the neurological sciences 20040830

• HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates.

  The Journal of biological chemistry 20040827

• Inhibition of furin by polyarginine-containing peptides: nanomolar inhibition by nona-D-arginine.

  The Journal of biological chemistry 20040827

• The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK.

  The Journal of biological chemistry 20040827

• Site-directed mutagenesis provides insight into racemization and transamination of alanine catalyzed by Treponema denticola cystalysin.

  The Journal of biological chemistry 20040827

• Chiral-selective aminoacylation of an RNA minihelix.

  Science (New York, N.Y.) 20040827

• Alpha-synuclein missense and multiplication mutations in autosomal dominant Parkinson's disease.

  Neuroscience letters 20040826

• Discriminating the helical forms of peptides by NMR and molecular dynamics simulation.

  Journal of the American Chemical Society 20040825

• Improvement of motor function in early Parkinson disease by safinamide.

  Neurology 20040824

• Syntheses and characterizations of a series of novel Ln6Cu24 clusters with amino acids as ligands.

  Inorganic chemistry 20040823

• Assembling heterocycle-tethered C-glycosyl and alpha-amino acid residues via 1,3-dipolar cycloaddition reactions.

  Organic letters 20040819

• Gain and loss of channel function by alanine substitutions in the transmembrane segments of the rat ATP-gated P2X2 receptor.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040818

• Supramolecular assembly of strongly chemisorbed size- and shape-defined chiral clusters: S- and R-alanine on Cu(110).

  Langmuir : the ACS journal of surfaces and colloids 20040817

• Substitutions of glutamate 110 and 111 in the middle helix 4 of human apolipoprotein A-I (apoA-I) by alanine affect the structure and in vitro functions of apoA-I and induce severe hypertriglyceridemia in apoA-I-deficient mice.

  Biochemistry 20040817

• Tilt and rotational pitch angle of membrane-inserted polypeptides from combined 15N and 2H solid-state NMR spectroscopy.

  Biochemistry 20040817

• Mature bovine articular cartilage contains abundant aggrecan that is C-terminally truncated at Ala719-Ala720, a site which is readily cleaved by m-calpain.

  The Biochemical journal 20040815

• Comparative effects of GLP-1 and GIP on cAMP production, insulin secretion, and in vivo antidiabetic actions following substitution of Ala8/Ala2 with 2-aminobutyric acid.

  Archives of biochemistry and biophysics 20040815

• NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding.

  The Journal of biological chemistry 20040813

• Localization of a catalytic intermediate bound to the FeMo-cofactor of nitrogenase.

  The Journal of biological chemistry 20040813

• Transport of meprin subunits through the secretory pathway: role of the transmembrane and cytoplasmic domains and oligomerization.

  The Journal of biological chemistry 20040813

• Alanine-scanning mutagenesis in the signature disulfide loop of the glycine receptor alpha 1 subunit: critical residues for activation and modulation.

  Biochemistry 20040810

• Mutational analysis of protein splicing, cleavage, and self-association reactions mediated by the naturally split Ssp DnaE intein.

  Biochemistry 20040810

• A structural requirement for processing the cardiac K+ channel KCNQ1.

  The Journal of biological chemistry 20040806

• Modulation of FcgammaRI (CD64) ligand binding by blocking peptides of periplakin.

  The Journal of biological chemistry 20040806

• Mechanisms of interactions of factor X and factor Xa with the acidic region in the factor VIII A1 domain.

  The Journal of biological chemistry 20040806

• Specific residues in plasmatocyte-spreading peptide are required for receptor binding and functional antagonism of insect immune cells.

  The Journal of biological chemistry 20040806

• How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor.

  Journal of molecular biology 20040806

• Structural basis for catalytic differences between alpha class human glutathione transferases hGSTA1-1 and hGSTA2-2 for glutathione conjugation of environmental carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide.

  Biochemistry 20040803

• The stereospecificity and catalytic efficiency of the tryptophan synthase-catalysed exchange of the alpha-protons of amino acids.

  The Biochemical journal 20040801

• Kinetic and structural analysis of the increased affinity of enoyl-ACP (acyl-carrier protein) reductase for triclosan in the presence of NAD+.

  The Biochemical journal 20040801

• Functional analysis of Chinese hamster phosphatidylserine synthase 1 through systematic alanine mutagenesis.

  The Biochemical journal 20040801

• The protein kinase C signaling pathway regulates a molecular switch between transactivation and transrepression activity of the peroxisome proliferator-activated receptor alpha.

  Molecular endocrinology (Baltimore, Md.) 20040801

• A simple, inexpensive, and precise magic angle spinning speed controller.

  Solid state nuclear magnetic resonance 20040801

• Assessing the reliability of density functional methods in the conformational study of polypeptides: the treatment of intraresidue nonbonding interactions.

  Journal of computational chemistry 20040801

• Increased risk of bladder cancer associated with a glutathione peroxidase 1 codon 198 variant.

  The Journal of urology 20040801

• Rebamipide increases the amount of mucin-like substances on the conjunctiva and cornea in the N-acetylcysteine-treated in vivo model.

  Cornea 20040801

• alpha-Synuclein-synaptosomal membrane interactions: implications for fibrillogenesis.

  European journal of biochemistry 20040801

• Mechanism of dichloroacetate-induced hypolactatemia in humans with or without cirrhosis.

  Metabolism: clinical and experimental 20040801

• NMR and molecular dynamics studies of an autoimmune myelin basic protein peptide and its antagonist: structural implications for the MHC II (I-Au)-peptide complex from docking calculations.

  European journal of biochemistry 20040801

• The factor V G1691A mutation is a risk for porencephaly: A case-control study.

  Annals of neurology 20040801

• Pregnenolone sulfate potentiates the effects of NMDA on hippocampal alanine and dopamine.

  Pharmacology, biochemistry, and behavior 20040801

• Comparison of thrombin-catalyzed fibrin polymerization and factor XIIIa-catalyzed cross-linking of fibrin among three recombinant variant fibrinogens, gamma 275C, gamma 275H, and gamma 275A.

  Journal of thrombosis and haemostasis : JTH 20040801

• The effect of sugar, amino acid, metal ion, and NaCl on model Maillard reaction under pH control.

  Amino acids 20040801

• Genetic variation in apolipoprotein D and Alzheimer's disease.

  Journal of neurology 20040801

• Effects of chard (Beta vulgaris L. var cicla) on the liver of the diabetic rats: a morphological and biochemical study.

  Bioscience, biotechnology, and biochemistry 20040801

• Association of estrogen receptor alpha polymorphisms with susceptibility to chronic hepatitis B virus infection.

  Hepatology (Baltimore, Md.) 20040801

• Glucose isomerase of the Streptomyces sp. SK strain: purification, sequence analysis and implication of alanine 103 residue in the enzyme thermostability and acidotolerance.

  Biochimie 20040801

• The host cell MAP kinase ERK-2 regulates viral assembly and release by phosphorylating the p6gag protein of HIV-1.

  The Journal of biological chemistry 20040730

• A feedback loop in the polo-like kinase activation pathway.

  The Journal of biological chemistry 20040730

• [Significance of serum calcium levels in colorectal cancer].

  Orvosi hetilap 20040725

• Synthesis of 3 10-helix-inducing constrained analogues of L-proline.

  The Journal of organic chemistry 20040723

• Alanine-scanning mutagenesis reveals a cytosine deaminase mutant with altered substrate preference.

  Biochemistry 20040720

• Characterization of structural determinants of granzyme B reveals potent mediators of extended substrate specificity.

  The Journal of biological chemistry 20040716

• A conserved motif for the transport of G protein-coupled receptors from the endoplasmic reticulum to the cell surface.

  The Journal of biological chemistry 20040716

• Tryptophan 621 and serine 667 residues of Daxx regulate its nuclear export during glucose deprivation.

  The Journal of biological chemistry 20040716

• Multiple molecular determinants in the carboxyl terminus regulate dopamine transporter export from endoplasmic reticulum.

  The Journal of biological chemistry 20040716

• Lysine beta311 of protein geranylgeranyltransferase type I partially replaces magnesium.

  The Journal of biological chemistry 20040716

• A molecular handoff between bacteriophage T7 DNA primase and T7 DNA polymerase initiates DNA synthesis.

  The Journal of biological chemistry 20040716

• Hepatitis C virus glycoprotein E2 contains a membrane-proximal heptad repeat sequence that is essential for E1E2 glycoprotein heterodimerization and viral entry.

  The Journal of biological chemistry 20040716

• Calcium/calmodulin-dependent protein kinase I inhibits neuronal nitric-oxide synthase activity through serine 741 phosphorylation.

  FEBS letters 20040716

• First principles investigation of vancomycin and teicoplanin binding to bacterial cell wall termini.

  Journal of the American Chemical Society 20040714

• Water molecule adsorption on short alanine peptides: how short is the shortest gas-phase alanine-based helix?

  Journal of the American Chemical Society 20040714

• Impact of replacement of D1 C-terminal alanine with glycine on structure and function of photosynthetic oxygen-evolving complex.

  The Journal of biological chemistry 20040709

• Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1.

  The EMBO journal 20040707

• The newly discovered Q motif of DEAD-box RNA helicases regulates RNA-binding and helicase activity.

  The EMBO journal 20040707

• Site-specific insertion of spin-labeled L-amino acids in Xenopus oocytes.

  Biochemistry 20040706

• Cysteine-scanning mutagenesis of the fifth external loop of serotonin transporter.

  Biochemistry 20040706

• Specific residues of the GDP/GTP exchange factor Bud5p are involved in establishment of the cell type-specific budding pattern in yeast.

  The Journal of biological chemistry 20040702

• Signals mediating cleavage of intercellular adhesion molecule-1.

  American journal of physiology. Cell physiology 20040701

• Novel reversible inactivation of cytochrome P450 2E1 T303A by tert-butyl acetylene: the role of threonine 303 in proton delivery to the active site of cytochrome P450 2E1.

  The Journal of pharmacology and experimental therapeutics 20040701

• Pyruvate shuttling during rest and exercise before and after endurance training in men.

  Journal of applied physiology (Bethesda, Md. : 1985) 20040701

• Forkhead l2 is expressed in the ovary and represses the promoter activity of the steroidogenic acute regulatory gene.

  Endocrinology 20040701

• Pharmacokinetics and pharmacodynamics of safinamide, a neuroprotectant with antiparkinsonian and anticonvulsant activity.

  Pharmacological research 20040701

• Receptor internalization-independent activation of Smad2 in activin signaling.

  Molecular endocrinology (Baltimore, Md.) 20040701

• Time-correlation between membrane depolarization and intracellular calcium in insulin secreting BRIN-BD11 cells: studies using FLIPR.

  Cell calcium 20040701

• Allele-specific loss of heterozygosity at the DAL-1/4.1B (EPB41L3) tumor-suppressor gene locus in the absence of mutation.

  Genes, chromosomes & cancer 20040701

• Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist.

  Neuropharmacology 20040701

• Kainate receptor agonists and antagonists mediate tolerance to kainic acid and reduce high-affinity GTPase activity in young, but not aged, rat hippocampus.

  Journal of neurochemistry 20040701

• Lack of major involvement of human uroplakin genes in vesicoureteral reflux: implications for disease heterogeneity.

  Kidney international 20040701

• Use of 2-azido-3-[125I]iodo-7,8-dibromodibenzo-p-dioxin as a probe to determine the relative ligand affinity of human versus mouse aryl hydrocarbon receptor in cultured cells.

  Molecular pharmacology 20040701

• Ionic strength reducers: an efficient approach to protein purification and crystallization. Application to two Rop variants.

  Acta crystallographica. Section D, Biological crystallography 20040701

• Correlation times and adiabatic barriers for methyl rotation in SNase.

  Journal of biomolecular NMR 20040701

• The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes.

  Diabetes 20040701

• Aerobic production of alanine by Escherichia coli aceF ldhA mutants expressing the Bacillus sphaericus alaD gene.

  Applied microbiology and biotechnology 20040701

• Substitution of conserved glycine residue by alanine in natural and synthetic neuropeptide ligands causes partial agonism at the stomoxytachykinin receptor.

  Journal of neurochemistry 20040701

• Binding energies of water to lithiated valine: formation of solution-phase structure in vacuo.

  Journal of the American Society for Mass Spectrometry 20040701

• Ex vivo proton MR spectroscopy (1H-MRS) for evaluation of human gastric carcinoma.

  Magnetic resonance imaging 20040701

• Nosocomial infection with vancomycin-dependent enterococci.

  Emerging infectious diseases 20040701

• Helical polymer carrying helical grafts from peptide-based acetylene macromonomers: synthesis.

  Macromolecular bioscience 20040625

• Extreme stability of an unsolvated alpha-helix.

  Journal of the American Chemical Society 20040623

• Alanine racemase free energy profiles from global analyses of progress curves.

  Journal of the American Chemical Society 20040623

• Structure of the His44 --> Ala single point mutant of the distal finger motif of HIV-1 nucleocapsid protein: a combined NMR, molecular dynamics simulation, and fluorescence study.

  Biochemistry 20040622

• Role of cysteine residues in the NCKX2 Na+/Ca(2+)-K+ Exchanger: generation of a functional cysteine-free exchanger.

  Biochemistry 20040622

• Interleukin-3 binding to the murine betaIL-3 and human betac receptors involves functional epitopes formed by domains 1 and 4 of different protein chains.

  The Journal of biological chemistry 20040618

• 14-3-3 binds to and mediates phosphorylation of microtubule-associated tau protein by Ser9-phosphorylated glycogen synthase kinase 3beta in the brain.

  The Journal of biological chemistry 20040618

• Allelic variation at the A218C tryptophan hydroxylase polymorphism influences agitation and aggression in Alzheimer's disease.

  Neuroscience letters 20040617

• Escherichia coli methionine aminopeptidase with Tyr168 to alanine substitution can improve the N-terminal processing of recombinant proteins with valine at the penultimate position.

  Analytical biochemistry 20040615

• Foldability, enzymatic activity, and interacting ability of barnase mutants obtained by permutation of secondary structure units.

  Biochemistry 20040608

• Functional domains in presenilin 1: the Tyr-288 residue controls gamma-secretase activity and endoproteolysis.

  The Journal of biological chemistry 20040604

• Mechanistic insights from a refined three-dimensional model of integrin alphaIIbbeta3.

  The Journal of biological chemistry 20040604

• Kinetic study of the H103A mutant yeast transketolase.

  FEBS letters 20040604

• Liquid chromatographic-mass spectrometric separation of oligoalanine peptide stereoisomers: influence of absolute configuration on enantioselectivity and two-dimensional separation of diastereomers and enantiomers.

  Journal of chromatography. A 20040604

• Lack of association between Alzheimer's disease and the promoter region polymorphisms of the nicastrin gene.

  Neuroscience letters 20040603

• Calcium-switch technique and junctional permeability in native rabbit esophageal epithelium.

  American journal of physiology. Gastrointestinal and liver physiology 20040601

• Insulin action during late pregnancy in the conscious dog.

  American journal of physiology. Endocrinology and metabolism 20040601

• Novel activating and inactivating mutations in the integrin beta1 subunit A domain.

  The Biochemical journal 20040601

• A coding mutation within the first exon of the human MD-2 gene results in decreased lipopolysaccharide-induced signaling.

  Genes and immunity 20040601

• Stability issues of covalently and noncovalently bonded peptide subunits.

  Journal of computational chemistry 20040601

• NLS-dependent nuclear localization of p120ctn is necessary to relieve Kaiso-mediated transcriptional repression.

  Journal of cell science 20040601

• Measurements of motionally averaged heteronuclear dipolar couplings in MAS NMR using R-type recoupling.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20040601

• Relationships between amino acid sequence and backbone torsion angle preferences.

  Proteins 20040601

• Mutation of the surface-exposed amino acid Trp to Ala in the FVIII C2 domain results in defective secretion of the otherwise functional protein.

  British journal of haematology 20040601

• A metabonomic investigation of the biochemical effects of mercuric chloride in the rat using 1H NMR and HPLC-TOF/MS: time dependent changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity.

  The Analyst 20040601

• Identification of functionally important residues in the pyridoxal-5'-phosphate-dependent catalytic antibody 15A9.

  Biochemistry 20040601

• Effect of chronic renal failure with metabolic acidosis on alanine metabolism in isolated liver cells.

  Clinical nutrition (Edinburgh, Scotland) 20040601

• Effect of reactive site loop elongation on the inhibitory activity of C1-inhibitor.

  Biochimica et biophysica acta 20040601

• Temperature-induced structural changes in putidaredoxin: a circular dichroism and UV-VIS absorption study.

  Biochimica et biophysica acta 20040601

• Changes in insulin sensitivity in response to troglitazone do not differ between subjects with and without the common, functional Pro12Ala peroxisome proliferator-activated receptor-gamma2 gene variant: results from the Troglitazone in Prevention of Diabetes (TRIPOD) study.

  Diabetes care 20040601

• Reduced reactivation rate in mutant CuZnSOD and progression rate of amyotrophic lateral sclerosis.

  European journal of neurology 20040601

• Adult-onset ataxia telangiectasia due to ATM 5762ins137 mutation homozygosity.

  Annals of neurology 20040601

• Manganese superoxide dismutase polymorphism, plasma antioxidants, cigarette smoking, and risk of breast cancer.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040601

• A structural model of EmrE, a multi-drug transporter from Escherichia coli.

  Biophysical journal 20040601

• Tilt angles of transmembrane model peptides in oriented and non-oriented lipid bilayers as determined by 2H solid-state NMR.

  Biophysical journal 20040601

• Dynein light chain 1, a p21-activated kinase 1-interacting substrate, promotes cancerous phenotypes.

  Cancer cell 20040601

• Ala-scan of ghrelin (1-14): interaction with the recombinant human ghrelin receptor.

  Peptides 20040601

• Allosteric modulation of glycine receptors is more efficacious for partial rather than full agonists.

  Neurochemistry international 20040601

• Decreased activity and expression of intestinal oligopeptide transporter PEPT1 in rats with hyperthyroidism in vivo.

  Pharmaceutical research 20040601

• Partial alanine scan of mast cell degranulating peptide (MCD): importance of the histidine- and arginine residues.

  Journal of peptide science : an official publication of the European Peptide Society 20040601

• A study of a Calpha,beta-didehydroalanine homo-oligopeptide series in the solid-state by 13C cross-polarization magic angle spinning NMR.

  Journal of peptide science : an official publication of the European Peptide Society 20040601

• Protein-protein interactions; coupling of structurally conserved residues and of hot spots across interfaces. Implications for docking.

  Structure (London, England : 1993) 20040601

• Modulating D-amino acid oxidase substrate specificity: production of an enzyme for analytical determination of all D-amino acids by directed evolution.

  Protein engineering, design & selection : PEDS 20040601

• Identification of a G protein-coupled receptor specifically responsive to beta-alanine.

  The Journal of biological chemistry 20040528

• A novel 3-step enantioselective synthesis of pyrenylalanine with subsequent incorporation into opioid, CCK, and melanotropin ligands.

  Biochemical and biophysical research communications 20040528

• Mutational analysis of the energetics of the GrpE.DnaK binding interface: equilibrium association constants by sedimentation velocity analytical ultracentrifugation.

  Journal of molecular biology 20040528

• A tyrosine-based sorting signal regulates intracellular trafficking of protease-activated receptor-1: multiple regulatory mechanisms for agonist-induced G protein-coupled receptor internalization.

  The Journal of biological chemistry 20040521

• Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo.

  The Journal of biological chemistry 20040521

• Peptide mapping of a novel discontinuous epitope of the major surface adhesin from Streptococcus mutans.

  The Journal of biological chemistry 20040521

• On the rational design of substrate mimetics: The function of docking approaches for the prediction of protease specificities.

  Organic & biomolecular chemistry 20040521

• Effect of the addition of wine distillery wastes to vineyard soils on the adsorption and mobility of fungicides.

  Journal of agricultural and food chemistry 20040519

• Role of the Rab11-associated intracellular pool of receptors formed by constitutive endocytosis of the beta isoform of the thromboxane A2 receptor (TP beta).

  Biochemistry 20040518

• Evidence for a proton transfer network and a required persulfide-bond-forming cysteine residue in Ni-containing carbon monoxide dehydrogenases.

  Biochemistry 20040518

• Role of the conserved arginine pair in proton and electron transfer in cytochrome C oxidase.

  Biochemistry 20040518

• NMR and mutagenesis studies on the phosphorylation region of human cardiac troponin I.

  Biochemistry 20040518

• Alanine scanning mutagenesis of the testosterone binding site of rat 3 alpha-hydroxysteroid dehydrogenase demonstrates contact residues influence the rate-determining step.

  Biochemistry 20040518

• Electron paramagnetic resonance reveals a large-scale conformational change in the cytoplasmic domain of phospholamban upon binding to the sarcoplasmic reticulum Ca-ATPase.

  Biochemistry 20040518

• Short sequences of non-proline residues can adopt the polyproline II helical conformation.

  Biochemistry 20040518

• Single-site mutation and secondary structure stability: an isodesmic reaction approach. The case of unnatural amino acid mutagenesis Ala-->Lac.

  The Journal of organic chemistry 20040514

• Positively charged side chains in protein farnesyltransferase enhance catalysis by stabilizing the formation of the diphosphate leaving group.

  Biochemistry 20040511

• Perforation of the tunnel wall in carbamoyl phosphate synthetase derails the passage of ammonia between sequential active sites.

  Biochemistry 20040511

• Influence of electric charge variation at residues 209 and 159 on the interaction of eIF4E with the mRNA 5' terminus.

  Biochemistry 20040511

• Aeromonas proteolytica aminopeptidase: an investigation of the mode of action using a quantum mechanical/molecular mechanical approach.

  Biochemistry 20040511

• Signal transduction mechanism of a peptide mimetic of interferon-gamma.

  Biochemistry 20040511

• Substitutions in an active site loop of Escherichia coli IscS result in specific defects in Fe-S cluster and thionucleoside biosynthesis in vivo.

  The Journal of biological chemistry 20040507

• The C-terminal domain is the primary determinant of histone H1 binding to chromatin in vivo.

  The Journal of biological chemistry 20040507

• Photoreactive bicyclic amino acids as substrates for mutant Escherichia coli phenylalanyl-tRNA synthetases.

  The Journal of biological chemistry 20040507

• Selective inactivation of adrenomedullin over calcitonin gene-related peptide receptor function by the deletion of amino acids 14-20 of the mouse calcitonin-like receptor.

  The Journal of biological chemistry 20040507

• Mapping of the insulin-like growth factor II binding site of the Type I insulin-like growth factor receptor by alanine scanning mutagenesis.

  FEBS letters 20040507

• Cleavage of the peptide bond of beta-alanyl-L-histidine (carnosine) induced by a Co(III)-amine complexes: reaction, structure and mechanism.

  Dalton transactions (Cambridge, England : 2003) 20040507

• Studies of the enzymic mechanism of Candida tenuis xylose reductase (AKR 2B5): X-ray structure and catalytic reaction profile for the H113A mutant.

  Biochemistry 20040504

• Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily.

  Biochemistry 20040504

• Crystal structures of artificial metalloproteins: tight binding of FeIII(Schiff-Base) by mutation of Ala71 to Gly in apo-myoglobin.

  Inorganic chemistry 20040503

• Mutation of cysteine 214 in Gi1 alpha subunit abolishes its endogenous GTPase activity.

  The Biochemical journal 20040501

• Glutamine synthesis in the developing porcine placenta.

  Biology of reproduction 20040501

• The anti-Müllerian hormone type II receptor: insights into the binding domains recognized by a monoclonal antibody and the natural ligand.

  The Biochemical journal 20040501

• Metabolic and mitogenic effects of IGF-I and insulin on muscle cells of rainbow trout.

  American journal of physiology. Regulatory, integrative and comparative physiology 20040501

• Aspartate transporter expression and activity in hypertrophic rat heart and ischaemia-reperfusion injury.

  The Journal of physiology 20040501

• Ultrastructural study of mitochondria in the spinal cord of transgenic mice with a G93A mutant SOD1 gene.

  Acta neuropathologica 20040501

• Slow component of axonal transport is impaired in the proximal axon of transgenic mice with a G93A mutant SOD1 gene.

  Acta neuropathologica 20040501

• Two histidines of the coat protein of turnip yellow mosaic virus at the capsid interior are crucial for viability.

  Proteins 20040501

• Metabolism of 13C-enriched D-fructose in hepatocytes from Goto-Kakizaki rats.

  International journal of molecular medicine 20040501

• Possible association of interleukin 1 gene locus polymorphisms with low back pain.

  Pain 20040501

• Rotational resonance in uniformly 13C-labeled solids: effects on high-resolution magic-angle spinning NMR spectra and applications in structural studies of biomolecular systems.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20040501

• Enteral glutamine but not alanine maintains small bowel barrier function after ischemia/reperfusion injury in rats.

  Shock (Augusta, Ga.) 20040501

• Alanine infusion during hypoglycaemia partly supports cognitive performance in healthy human subjects.

  Diabetic medicine : a journal of the British Diabetic Association 20040501

• The role of glycine residues in the function of human organic anion transporter 4.

  Molecular pharmacology 20040501

• Conformation and dynamics of the [3-(13)C]Ala, [1-(13)C]Val-labeled truncated pharaonis transducer, pHtrII(1-159), as revealed by site-directed (13)C solid-state NMR: changes due to association with phoborhodopsin (sensory rhodopsin II).

  Biophysical journal 20040501

• Effects of high-intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis.

  Muscle & nerve 20040501

• Transport of the phosphonodipeptide alafosfalin by the H+/peptide cotransporters PEPT1 and PEPT2 in intestinal and renal epithelial cells.

  European journal of biochemistry 20040501

• Mitochondrial and sarcoplasmic proteins, but not myosin heavy chain, are sensitive to leucine supplementation in old rat skeletal muscle.

  Experimental gerontology 20040501

• Compounds of 6Li and natural Li for EPR dosimetry in photon/neutron mixed radiation fields.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040501

• EPR study of light illumination effects on radicals in gamma-irradiated L-alanine.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040501

• EPR study of gamma induced radicals in amino acid powders.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040501

• Ptr ToxA requires multiple motifs for complete activity.

  Molecular plant-microbe interactions : MPMI 20040501

• Dogmas and controversies in the handling of nitrogenous wastes: ammonia tolerance in the oriental weatherloach Misgurnus anguillicaudatus.

  The Journal of experimental biology 20040501

• Genetic interactions with C-terminal domain (CTD) kinases and the CTD of RNA Pol II suggest a role for ESS1 in transcription initiation and elongation in Saccharomyces cerevisiae.

  Genetics 20040501

• Comparison of age estimated from degree of racemization of aspartic acid, glutamic acid and alanine in the femur.

  Journal of forensic sciences 20040501

• Hb Cardarelli [beta86(F2)Ala-->Pro]: a new unstable and hyperaffine variant in association with beta(+)-thalassemia.

  Hemoglobin 20040501

• [Association of Pro12Ala mutation in peroxisome proliferator-activated receptor gamma 2 with obesity and diabetes in Chinese population].

  Wei sheng yan jiu = Journal of hygiene research 20040501

• Two-dimensional alanine scanning mutational analysis of the interaction between the vitamin D receptor and its ligands: studies of A-ring modified 19-norvitamin D analogs.

  The Journal of steroid biochemistry and molecular biology 20040501

• Mechanism of hydroxyl radical scavenging by rebamipide: identification of mono-hydroxylated rebamipide as a major reaction product.

  Free radical research 20040501

• [Is obesity associated with a polymorphism Pro12Ala and Pro115Gln in PPARgamma gene?].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20040501

• Intramolecular interaction energies in model alanine and glycine tetrapeptides. Evaluation of anisotropy, polarization, and correlation effects. A parallel ab initio HF/MP2, DFT, and polarizable molecular mechanics study.

  Journal of computational chemistry 20040430

• Indiscriminate glycosylation of procarboxypeptidase Y expressed in Pichia pastoris.

  Carbohydrate research 20040428

• Formation of a semiquinone at the QB site by A- or B-branch electron transfer in the reaction center from Rhodobacter sphaeroides.

  Biochemistry 20040427

• Effects of Parkinson's disease-linked mutations on the structure of lipid-associated alpha-synuclein.

  Biochemistry 20040427

• Determination of derivatized l-alanosine in plasma by liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040425

• Clathrin-mediated endocytosis of Na+,K+-ATPase in response to parathyroid hormone requires ERK-dependent phosphorylation of Ser-11 within the alpha1-subunit.

  The Journal of biological chemistry 20040423

• Conformational flexibility of PEP mutase.

  Biochemistry 20040420

• Substitution of the conserved Arg-Tyr dyad selectively disrupts the hydrolysis phase of the IMP dehydrogenase reaction.

  Biochemistry 20040420

• 3C-like proteinase from SARS coronavirus catalyzes substrate hydrolysis by a general base mechanism.

  Biochemistry 20040420

• Identification of the amino acid residues of the platelet glycoprotein Ib (GPIb) essential for the von Willebrand factor binding by clustered charged-to-alanine scanning mutagenesis.

  The Journal of biological chemistry 20040416

• Synthesis of gramicidin S and its analogues via an on-resin macrolactamization assisted by a predisposed conformation of the linear precursors.

  The Journal of organic chemistry 20040416

• Essential Amino Acid Residues Controlling the Unique Regioselectivity of Heme Oxygenase in Pseudomonas aeruginosa.

  Journal of the American Chemical Society 20040414

• The putative 'nucleation site' in human H-chain ferritin is not required for mineralization of the iron core.

  Biochemistry 20040413

• Trp2063 and Trp2064 in the factor Va C2 domain are required for high-affinity binding to phospholipid membranes but not for assembly of the prothrombinase complex.

  Biochemistry 20040413

• Roles of the proline-rich domain in SLP-76 subcellular localization and T cell function.

  The Journal of biological chemistry 20040409

• NMR analysis shows that a b-type variant of Hydrogenobacter thermophilus cytochrome c552 retains its native structure.

  The Journal of biological chemistry 20040409

• Specificity of the endonuclease activity of the baculovirus alkaline nuclease for single-stranded DNA.

  The Journal of biological chemistry 20040409

• Hydrogen bonding in a model bacteriochlorophyll-binding site drives assembly of light harvesting complex.

  The Journal of biological chemistry 20040409

• Post-translational formylglycine modification of bacterial sulfatases by the radical S-adenosylmethionine protein AtsB.

  The Journal of biological chemistry 20040409

• S-palmitoylation modulates human estrogen receptor-alpha functions.

  Biochemical and biophysical research communications 20040409

• The active site of the Escherichia coli glycogen synthase is similar to the active site of retaining GT-B glycosyltransferases.

  Biochemical and biophysical research communications 20040409

• Heat capacity and electron spin echo evidence for low frequency vibrational modes and lattice disorder in L-alanine at cryogenic temperatures.

  The Journal of chemical physics 20040408

• Kinetic role of helix caps in protein folding is context-dependent.

  Biochemistry 20040406

• Reversal of negative charges on the surface of Escherichia coli thioredoxin: pockets versus protrusions.

  Biochemistry 20040406

• Pre-steady-state kinetics of RB69 DNA polymerase and its exo domain mutants: effect of pH and thiophosphoryl linkages on 3'-5' exonuclease activity.

  Biochemistry 20040406

• Conformational changes within the cytosolic portion of phospholamban upon release of Ca-ATPase inhibition.

  Biochemistry 20040406

• An appraisal of multiple NADPH binding-site models proposed for cytochrome P450 reductase, NO synthase, and related diflavin reductase systems.

  Biochemistry 20040406

• Characterization of the interaction between the N-terminal extension of human cardiac troponin I and troponin C.

  Biochemistry 20040406

• The urea cycle and related pathways in the liver of Walker-256 tumor-bearing rats.

  Biochimica et biophysica acta 20040405

• Inactivation and recovery in Kv1.4 K+ channels: lipophilic interactions at the intracellular mouth of the pore.

  The Journal of physiology 20040401

• Quantifying rates of protein synthesis in humans by use of 2H2O: application to patients with end-stage renal disease.

  American journal of physiology. Endocrinology and metabolism 20040401

• Studies of Abeta pharmacodynamics in the brain, cerebrospinal fluid, and plasma in young (plaque-free) Tg2576 mice using the gamma-secretase inhibitor N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide (LY-411575).

  The Journal of pharmacology and experimental therapeutics 20040401

• Potentiometric investigation of the effect of the pH on the ionic transfer of some amino acids at the interface between two immiscible electrolyte solutions.

  Bioelectrochemistry (Amsterdam, Netherlands) 20040401

• Characterization of recombinant mannan-binding lectin-associated serine protease (MASP)-3 suggests an activation mechanism different from that of MASP-1 and MASP-2.

  Journal of immunology (Baltimore, Md. : 1950) 20040401

• Mutational analyses of the recombinant globular regions of human C1q A, B, and C chains suggest an essential role for arginine and histidine residues in the C1q-IgG interaction.

  Journal of immunology (Baltimore, Md. : 1950) 20040401

• Loss of the mRNA-like region in mitochondrial tmRNAs of jakobids.

  RNA (New York, N.Y.) 20040401

• Ammonium formate, a compound for sensitive EPR dosimetry.

  Radiation research 20040401

• Semisynthesis of an analogue of antitumor bicyclic hexapeptide RA-VII by fixing the Ala-2/Tyr-3 bond to Cis by incorporating a triazole cis-amide bond surrogate.

  Organic letters 20040401

• Knockout of the alanine racemase gene in Lactobacillus plantarum results in septation defects and cell wall perforation.

  FEMS microbiology letters 20040401

• Rescue of protein splicing activity from a Magnetospirillum magnetotacticum intein-like element.

  Biochemical Society transactions 20040401

• Protein kinase B-alpha inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors.

  Diabetes 20040401

• Prevalence of thrombophilia in women with severe ovarian hyperstimulation syndrome and cost-effectiveness of screening.

  Fertility and sterility 20040401

• Repositioning of charged I-II loop amino acid residues within the electric field by beta subunit as a novel working hypothesis for the control of fast P/Q calcium channel inactivation.

  The European journal of neuroscience 20040401

• A conditional marker gene allowing both positive and negative selection in plants.

  Nature biotechnology 20040401

• Identification of amino acid residues responsible for agonist-induced down-regulation of histamine H(1) receptors.

  Journal of pharmacological sciences 20040401

• A gel electrophoresis method for detection of mitochondrial DNA mutation (3243 tRNA(Leu (UUR))) applied to a Norwegian family with diabetes mellitus and hearing loss.

  Scandinavian journal of clinical and laboratory investigation 20040401

• Protective effects of selected medicinal plants against protein degradation, lipid peroxidation and deformability loss of oxidatively stressed human erythrocytes.

  Phytotherapy research : PTR 20040401

• Barrier-free intermolecular proton transfer induced by excess electron attachment to the complex of alanine with uracil.

  The Journal of chemical physics 20040401

• The folding pathway of barnase: the rate-limiting transition state and a hidden intermediate under native conditions.

  Biochemistry 20040330

• Mutational, NMR, and NH exchange studies of the tight and selective binding of 8-oxo-dGMP by the MutT pyrophosphohydrolase.

  Biochemistry 20040330

• Residues in the hydrophilic face of putative helix 8 of oxytocin receptor are important for receptor function.

  Biochemistry 20040330

• Determinants of high-affinity binding and receptor activation in the N-terminus of CCL-19 (MIP-3 beta).

  Biochemistry 20040330

• Phosphorylated p40PHOX as a negative regulator of NADPH oxidase.

  Biochemistry 20040330

• Evidence that C promoter-binding factor 1 binding is required for Notch-1-mediated repression of activator protein-1.

  The Journal of biological chemistry 20040326

• Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions.

  The Journal of biological chemistry 20040326

• Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis.

  The Journal of biological chemistry 20040326

• Ubiquitin recognition by the human TSG101 protein.

  Molecular cell 20040326

• Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression.

  Molecular cell 20040326

• Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity.

  Biochemistry 20040323

• Is aromaticity essential for trapping the catalytic histidine 447 in human acetylcholinesterase?

  Biochemistry 20040323

• Evidence that the C-terminus of the D1 polypeptide of photosystem II is ligated to the manganese ion that undergoes oxidation during the S1 to S2 transition: an isotope-edited FTIR study.

  Biochemistry 20040323

• Mutant cholinesterases possessing enhanced capacity for reactivation of their phosphonylated conjugates.

  Biochemistry 20040323

• Reaction of Pseudomonas fluorescens kynureninase with beta-benzoyl-L-alanine: detection of a new reaction intermediate and a change in rate-determining step.

  Biochemistry 20040323

• Molecular simulation of the reversible mechanical unfolding of proteins.

  The Journal of chemical physics 20040322

• Enantioselective molecular recognition between beta-sheets.

  Journal of the American Chemical Society 20040317

• Determinants of potency on alpha-conotoxin MII, a peptide antagonist of neuronal nicotinic receptors.

  Biochemistry 20040316

• Microtubule-kinesin interface mutants reveal a site critical for communication.

  Biochemistry 20040316

• Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif.

  The Biochemical journal 20040315

• Hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome with evidence of mitochondrial dysfunction due to a novel SLC25A15 (ORNT1) gene mutation in a Palestinian family.

  Journal of the neurological sciences 20040315

• Glu496 to Ala polymorphism in the P2X7 receptor impairs ATP-induced IL-1 beta release from human monocytes.

  Journal of immunology (Baltimore, Md. : 1950) 20040315

• Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing.

  The Journal of biological chemistry 20040312

• Catalytic activity of human ADAM33.

  The Journal of biological chemistry 20040312

• Residue Asp-189 controls both substrate binding and the monovalent cation specificity of thrombin.

  The Journal of biological chemistry 20040312

• The C-terminal nonapeptide of mature chemerin activates the chemerin receptor with low nanomolar potency.

  The Journal of biological chemistry 20040312

• The conformation of tetraalanine in water determined by polarized Raman, FT-IR, and VCD spectroscopy.

  Journal of the American Chemical Society 20040310

• Pi-helix preference in unsolvated peptides.

  Journal of the American Chemical Society 20040310

• Contributions of amino acid side chains to the kinetics and thermodynamics of the bivalent binding of protein L to Ig kappa light chain.

  Biochemistry 20040309

• B beta Glu397 and B beta Asp398 but not B beta Asp432 are required for 'B:b' interactions.

  Biochemistry 20040309

• Calcium-binding site beta 2, adjacent to the 'b' polymerization site, modulates lateral aggregation of protofibrils during fibrin polymerization.

  Biochemistry 20040309

• Structure-activity studies on the cleavage of an RNA analogue by a potent dinuclear metal ion catalyst: effect of changing the metal ion.

  Inorganic chemistry 20040308

• A single amino acid residue defines the difference in ovalicin sensitivity between type I and II methionine aminopeptidases.

  The Journal of biological chemistry 20040305

• Empirical relationships between isotope-edited IR spectra and helix geometry in model peptides.

  Journal of the American Chemical Society 20040303

• Nature of vibrational coupling in helical peptides: an isotopic labeling study.

  Journal of the American Chemical Society 20040303

• Chemical rescue of a site-specific mutant of bacterial copper amine oxidase for generation of the topa quinone cofactor.

  Biochemistry 20040302

• The raised midpoint potential of the [2Fe2S] cluster of cytochrome bc1 is mediated by both the Qo site occupants and the head domain position of the Fe-S protein subunit.

  Biochemistry 20040302

• Resonance Raman spectroscopy reveals the origin of an intermediate wavelength form in photoactive yellow protein.

  Biochemistry 20040302

• Alanine-stimulated exocytosis in Aplysia enterocytes: effect of Na+ transport and requirement for actin filaments.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20040301

• Differences in recurrent COL7A1 mutations in dystrophic epidermolysis bullosa: ethnic-specific and worldwide recurrent mutations.

  Archives of dermatological research 20040301

• Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands.

  Journal of structural biology 20040301

• A peptide that antagonizes TCR-mediated reactions with both syngeneic and allogeneic agonists: functional and structural aspects.

  Journal of immunology (Baltimore, Md. : 1950) 20040301

• Distinct domains of the mu-opioid receptor control uncoupling and internalization.

  Molecular pharmacology 20040301

• Defining the minimum size of a hydrophobic cluster in two-stranded alpha-helical coiled-coils: effects on protein stability.

  Protein science : a publication of the Protein Society 20040301

• Transcription activation at the Escherichia coli melAB promoter: interactions of MelR with its DNA target site and with domain 4 of the RNA polymerase sigma subunit.

  Molecular microbiology 20040301

• Levodopa-responsive aromatic L-amino acid decarboxylase deficiency.

  Annals of neurology 20040301

• (1E)-2-(Diacetylamino)-1-methylprop-1-enyl acetate.

  Acta crystallographica. Section C, Crystal structure communications 20040301

• Cu/Zn-superoxide dismutase (GLY93-->ALA) mutation alters AMPA receptor subunit expression and function and potentiates kainate-mediated toxicity in motor neurons in culture.

  Neurobiology of disease 20040301

• Peptide sequence and amyloid formation; molecular simulations and experimental study of a human islet amyloid polypeptide fragment and its analogs.

  Structure (London, England : 1993) 20040301

• Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun by mobile genetic elements.

  PLoS biology 20040301

• A novel mutation, Thr65Ala, in the MPZ gene in a patient with Charcot-Marie-Tooth type 1B disease with focally folded myelin.

  Neuromuscular disorders : NMD 20040301

• Effect of adding and removing N-glycosylation recognition sites on the thermostability of barley alpha-glucosidase.

  Protein engineering, design & selection : PEDS 20040301

• In situ-forming pharmaceutical organogels based on the self-assembly of L-alanine derivatives.

  Pharmaceutical research 20040301

• Neurological proteins are not enriched for repetitive sequences.

  Genetics 20040301

• Cysteine repeat domains and adjacent sequences determine distinct bone morphogenetic protein modulatory activities of the Drosophila Sog protein.

  Genetics 20040301

• A novel mechanism of intragenic complementation between Phe to Ala calmodulin mutations.

  Journal of biochemistry 20040301

• Cluster analysis of water molecules in alanine racemase and their putative structural role.

  Protein engineering, design & selection : PEDS 20040301

• The interaction of the penetration enhancer DDAIP with a phospholipid model membrane.

  International journal of pharmaceutics 20040301

• Preventive effect of the flavonoid, wogonin, against ethanol-induced gastric mucosal damage in rats.

  Digestive diseases and sciences 20040301

• Changes in soil chemical properties and microbial activities in response to the fungicide Ridomil Gold plus copper.

  International journal of environmental research and public health 20040301

• Functional characterization of Caenorhabditis elegans heteromeric amino acid transporters.

  The Journal of biological chemistry 20040227

• The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization.

  Molecular cell 20040227

• Role of active-site residues Thr81, Ser82, Thr85, Gln157, and Tyr158 in yeast cystathionine beta-synthase catalysis and reaction specificity.

  Biochemistry 20040224

• Modulating calcitonin fibrillogenesis: an antiparallel alpha-helical dimer inhibits fibrillation of salmon calcitonin.

  The Journal of biological chemistry 20040220

• p120 catenin associates with microtubules: inverse relationship between microtubule binding and Rho GTPase regulation.

  The Journal of biological chemistry 20040220

• Phosphorylation and stabilization of ATP binding cassette transporter A1 by synthetic amphiphilic helical peptides.

  The Journal of biological chemistry 20040220

• Prebiotic amino acids as asymmetric catalysts.

  Science (New York, N.Y.) 20040220

• The disassembly and reassembly of mutants of Escherichia coli heat-labile enterotoxin: replacement of proline 93 does not abolish the reassembly-competent and reassembly-incompetent states.

  Biochemistry 20040217

• The Q267E mutation in the sodium/iodide symporter (NIS) causes congenital iodide transport defect (ITD) by decreasing the NIS turnover number.

  Journal of cell science 20040215

• Association between the HOXA1 A218G polymorphism and increased head circumference in patients with autism.

  Biological psychiatry 20040215

• A molecular dynamics study of the dielectric properties of aqueous solutions of alanine and alanine dipeptide.

  The Journal of chemical physics 20040215

• A novel CRM1-mediated nuclear export signal governs nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase following genotoxic stress.

  The Journal of biological chemistry 20040213

• Enzymatic and molecular characteristics of the efficiency and specificity of exfoliative toxin cleavage of desmoglein 1.

  The Journal of biological chemistry 20040213

• Synergy between conserved ABC signature Ser residues in P-glycoprotein catalysis.

  The Journal of biological chemistry 20040213

• Two arginines in the cytoplasmic C-terminal domain are essential for voltage-dependent regulation of A-type K+ current in the Kv4 channel subfamily.

  The Journal of biological chemistry 20040213

• Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding.

  The Journal of biological chemistry 20040213

• Crystal structure of a cAMP-dependent protein kinase mutant at 1.26A: new insights into the catalytic mechanism.

  Journal of molecular biology 20040213

• JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD.

  Molecular cell 20040213

• Catalytic mechanism of the cyclohydrolase activity of human aminoimidazole carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase.

  Biochemistry 20040210

• Three-dimensional structure of kynureninase from Pseudomonas fluorescens.

  Biochemistry 20040210

• Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.

  Biochemistry 20040210

• Crystallographic studies on structural features that determine the enzymatic specificity and potency of human angiogenin: Thr44, Thr80, and residues 38-41.

  Biochemistry 20040210

• Trypsin disrupts the trafficking of the human dopamine transporter by alpha-synuclein and its A30P mutant.

  Biochemistry 20040210

• Enzymatic mechanism of low-activity mouse alcohol dehydrogenase 2.

  Biochemistry 20040210

• The side chain of aspartic acid 69 dictates the folding mechanism of Bacillus subtilis HPr.

  Biochemistry 20040210

• Antioxidant action of L-alanine: heme oxygenase-1 and ferritin as possible mediators.

  Biochemical and biophysical research communications 20040206

• Mutation S363A in the human delta-opioid receptor selectively reduces down-regulation by a peptide agonist.

  European journal of pharmacology 20040206

• New tools for mass isotopomer data evaluation in (13)C flux analysis: mass isotope correction, data consistency checking, and precursor relationships.

  Biotechnology and bioengineering 20040205

• Temperature and pressure effects on conformational equilibria of alanine dipeptide in aqueous solution.

  Biopolymers 20040205

• Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25.

  Neuron 20040205

• Tazobactam forms a stoichiometric trans-enamine intermediate in the E166A variant of SHV-1 beta-lactamase: 1.63 A crystal structure.

  Biochemistry 20040203

• Investigating the importance of the flexible hinge in caerin 1.1: solution structures and activity of two synthetically modified caerin peptides.

  Biochemistry 20040203

• Discrimination between different methylation states of chemotaxis receptor Tar by receptor methyltransferase CheR.

  Biochemistry 20040203

• G-1:C73 recognition by an arginine cluster in the active site of Escherichia coli histidyl-tRNA synthetase.

  Biochemistry 20040203

• Role of the active site cysteine of DpgA, a bacterial type III polyketide synthase.

  Biochemistry 20040203

• A two-module region of the low-density lipoprotein receptor sufficient for formation of complexes with apolipoprotein E ligands.

  Biochemistry 20040203

• Kinetic characterization of yeast pyruvate carboxylase isozyme Pyc1 and the Pyc1 mutant, C249A.

  Biochemistry 20040203

• Computational alanine scanning of protein-protein interfaces.

  Science's STKE : signal transduction knowledge environment 20040203

• Arachidonic acid, palmitic acid and glucose are important for the modulation of clonal pancreatic beta-cell insulin secretion, growth and functional integrity.

  Clinical science (London, England : 1979) 20040201

• Functional characterization and cold sensitivity of T1313A, a new mutation of the skeletal muscle sodium channel causing paramyotonia congenita in humans.

  The Journal of physiology 20040201

• Catechol-o-methyltransferase (COMT) and proline dehydrogenase (PRODH) mRNAs in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and major depression.

  Synapse (New York, N.Y.) 20040201

• Receptor-controlled phosphorylation of alpha 1 soluble guanylyl cyclase enhances nitric oxide-dependent cyclic guanosine 5'-monophosphate production in pituitary cells.

  Molecular endocrinology (Baltimore, Md.) 20040201

• Structure-based method for analyzing protein-protein interfaces.

  Journal of molecular modeling 20040201

• Variation in the FABP2 promoter affects gene expression: implications for prior association studies.

  Diabetologia 20040201

• A microtiter fluorometric assay to detect the germination of Bacillus anthracis spores and the germination inhibitory effects of antibodies.

  Journal of microbiological methods 20040201

• Retinal function loss after monocarboxylate transport inhibition.

  Investigative ophthalmology & visual science 20040201

• Influence of the polymorphisms Tpr64Arg in the beta 3-adrenergic receptor gene and Pro12Ala in the PPAR gamma 2 gene on metabolic syndrome-related phenotypes in an indigenous population of the Brazilian Amazon.

  Diabetes care 20040201

• Nitrogen metabolism in the African lungfish (Protopterus dolloi) aestivating in a mucus cocoon on land.

  The Journal of experimental biology 20040201

• The impact of Lys-->Arg surface mutations on the crystallization of the globular domain of RhoGDI.

  Acta crystallographica. Section D, Biological crystallography 20040201

• An ALS mouse model with a permeable blood-brain barrier benefits from systemic cyclosporine A treatment.

  Journal of neurochemistry 20040201

• L-alanyl-L-glutamine-supplemented parenteral nutrition improves infectious morbidity in secondary peritonitis.

  Clinical nutrition (Edinburgh, Scotland) 20040201

• ADAM family protein Mde10 is essential for development of spore envelopes in the fission yeast Schizosaccharomyces pombe.

  Eukaryotic cell 20040201

• A covalently linked recombinant albumin dimer is more rapidly cleared in vivo than are wild-type and mutant C34A albumin.

  The Journal of laboratory and clinical medicine 20040201

• Does initial and delayed heart rate predict mortality in patients with acute coronary syndromes?

  Clinical cardiology 20040201

• Intestinal FABP2 A54T polymorphism: association with insulin resistance and obesity in women.

  Obesity research 20040201

• Combination of cyclodextrins and polymeric surfactants for chiral separations.

  Electrophoresis 20040201

• Activated p38MAPK is a novel component of the intracellular inclusions found in human amyotrophic lateral sclerosis and mutant SOD1 transgenic mice.

  Journal of neuropathology and experimental neurology 20040201

• Identification of a new mouse Cd1d2 allele.

  European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 20040201

• In vivo properties of thiol inhibitors of the three vasopeptidases NEP, ACE and ECE are improved by introduction of a 7-azatryptophan in P2' position.

  The journal of peptide research : official journal of the American Peptide Society 20040201

• Probing essential residues for cellular uptake with a cationic nuclear localization signal sequence.

  The journal of peptide research : official journal of the American Peptide Society 20040201

• New tools for the control of peptide conformation: the helicogenic Calpha-methyl, Calpha-cyclohexylglycine.

  The journal of peptide research : official journal of the American Peptide Society 20040201

• Isotopic discrimination between D-[1-(13)C]fructose and D-[2-(13)C]fructose in rat liver cells.

  Biochimie 20040201

• Ala226 to Gly and Ser189 to Asp mutations convert rat chymotrypsin B to a trypsin-like protease.

  Protein engineering, design & selection : PEDS 20040201

• Cartilage link protein interacts with neurocan, which shows hyaluronan binding characteristics different from CD44 and TSG-6.

  Matrix biology : journal of the International Society for Matrix Biology 20040201

• Identification and characterization of a nitrate transporter gene in Neurospora crassa.

  Biochemical genetics 20040201

• Degradation, receptor binding, insulin secreting and antihyperglycaemic actions of palmitate-derivatised native and Ala8-substituted GLP-1 analogues.

  Biological chemistry 20040201

• Dial tm for rescue: tmRNA engages ribosomes stalled on defective mRNAs.

  Current opinion in structural biology 20040201

• Rebamipide activates genes encoding angiogenic growth factors and Cox2 and stimulates angiogenesis: a key to its ulcer healing action?

  Digestive diseases and sciences 20040201

• Hepatopancreas gluconeogenesis and glycogen content during fasting in crabs previously maintained on a high-protein or carbohydrate-rich diet.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20040201

• The contribution of the exosite residues of plasminogen activator inhibitor-1 to proteinase inhibition.

  The Journal of biological chemistry 20040130

• Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding.

  The Journal of biological chemistry 20040130

• The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5.

  The Journal of biological chemistry 20040130

• The interface between self-assembling erythropoietin receptor transmembrane segments corresponds to a membrane-spanning leucine zipper.

  The Journal of biological chemistry 20040130

• Activated eIF4E-binding protein slows G1 progression and blocks transformation by c-myc without inhibiting cell growth.

  The Journal of biological chemistry 20040130

• Role of His-16 in turnover of T4 pyrimidine dimer glycosylase.

  The Journal of biological chemistry 20040130

• A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2.

  The Journal of biological chemistry 20040130

• A structure-activity relationship study on N-arachidonoyl-amino acids as possible endogenous inhibitors of fatty acid amide hydrolase.

  Biochemical and biophysical research communications 20040130

• Mutational analysis of GstI protein, a glutamine synthetase translational inhibitor of Rhizobium leguminosarum.

  FEBS letters 20040130

• A residue in MutY important for catalysis identified by photocross-linking and mass spectrometry.

  Biochemistry 20040127

• Roles of N-terminal region residues Lys11, Arg13, and Arg24 of antithrombin in heparin recognition and in promotion and stabilization of the heparin-induced conformational change.

  Biochemistry 20040127

• Effects of backbone contacts 3' to the abasic site on the cleavage and the product binding by human apurinic/apyrimidinic endonuclease (APE1).

  Biochemistry 20040127

• Superoxide reductase from Desulfoarculus baarsii: identification of protonation steps in the enzymatic mechanism.

  Biochemistry 20040127

• Inhibitory actions of serotonin on glutamate release in dorsal medulla suppress systemic arterial pressure of cats.

  Neuroscience letters 20040123

• Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate.

  Journal of the National Cancer Institute 20040121

• An experimental and Monte Carlo investigation of the energy dependence of alanine/EPR dosimetry: I. Clinical x-ray beams.

  Physics in medicine and biology 20040121

• Phospholamban binds in a compact and ordered conformation to the Ca-ATPase.

  Biochemistry 20040120

• Disentangling the web of allosteric communication in a homotetramer: heterotropic inhibition of phosphofructokinase from Bacillus stearothermophilus.

  Biochemistry 20040120

• Structure and mechanism of mRNA cap (guanine-N7) methyltransferase.

  Molecular cell 20040116

• A mechanism for Wnt coreceptor activation.

  Molecular cell 20040116

• Surprisingly stable helical conformations in alpha/beta-peptides by incorporation of cis-beta-aminocyclopropane carboxylic acids.

  Angewandte Chemie (International ed. in English) 20040116

• PKA phosphorylation and 14-3-3 interaction regulate the function of neurofibromatosis type I tumor suppressor, neurofibromin.

  FEBS letters 20040116

• Expression and functional properties of group I metabotropic glutamate receptors in bovine chromaffin cells.

  Journal of neuroscience research 20040115

• An altered self-peptide with superagonist activity blocks a CD8-mediated mouse model of type 1 diabetes.

  Journal of immunology (Baltimore, Md. : 1950) 20040115

• Support for RGS4 as a susceptibility gene for schizophrenia.

  Biological psychiatry 20040115

• An Msh2 point mutation uncouples DNA mismatch repair and apoptosis.

  Cancer research 20040115

• Alanine : glyoxylate aminotransferase of Saccharomyces cerevisiae-encoding gene AGX1 and metabolic significance.

  Yeast (Chichester, England) 20040115

• Structural bases for CRMP function in plexin-dependent semaphorin3A signaling.

  The EMBO journal 20040114

• Nonhepatic glucose production in humans.

  American journal of physiology. Endocrinology and metabolism 20040101

• Deletion of alanine 2201 in the FVIII C2 domain results in mild hemophilia A by impairing FVIII binding to VWF and phospholipids and destroys a major FVIII antigenic determinant involved in inhibitor development.

  Blood 20040101

• Troglitazone acts by PPARgamma and PPARgamma-independent pathways on LLC-PK1-F+ acid-base metabolism.

  American journal of physiology. Renal physiology 20040101

• Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice.

  Journal of neurophysiology 20040101

• Evidence for dynamic clustering of carboxy-terminal aromatic amino acids in TonB-dependent energy transduction.

  Molecular microbiology 20040101

• FT-Raman and FTIR spectroscopic studies of N-octadecanoyl-L-alanine amphiphiles.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040101

• 2H[19F] REDOR for distance measurements in biological solids using a double resonance spectrometer.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20040101

• Does peroxisome proliferator-activated receptor gamma genotype (Pro12ala) modify the association of physical activity and dietary fat with fasting insulin level?

  Metabolism: clinical and experimental 20040101

• N-linked glycosylation of dipeptidyl peptidase IV (CD26): effects on enzyme activity, homodimer formation, and adenosine deaminase binding.

  Protein science : a publication of the Protein Society 20040101

• Helix formation and the unfolded state of a 52-residue helical protein.

  Protein science : a publication of the Protein Society 20040101

• The factor V C1 domain is involved in membrane binding: identification of functionally important amino acid residues within the C1 domain of factor V using alanine scanning mutagenesis.

  Thrombosis and haemostasis 20040101

• Critical residues for ligand binding in blade 2 of the propeller domain of the integrin alphaIIb subunit.

  Thrombosis and haemostasis 20040101

• Free amino acids mimic the anabolic but not the proliferative effect of albumin in OK proximal tubular cells.

  Cell biochemistry and function 20040101

• Arg-16 and Arg-21 in the N-terminal region of the triple-gene-block protein 1 of Bamboo mosaic virus are essential for virus movement.

  The Journal of general virology 20040101

• Association study of onset age, attempted suicide, aggressive behavior, and schizophrenia with a serotonin 1B receptor (A-161T) genetic polymorphism.

  Neuropsychobiology 20040101

• A window into cellular metabolism: hepatic metabolism of (15)N-labelled substrates.

  Metabolic engineering 20040101

• High-level production of hyperthermophilic cellulase in the Bacillus brevis expression and secretion system.

  Bioscience, biotechnology, and biochemistry 20040101

• Increased manganese concentration in the liver after oral intake.

  Academic radiology 20040101

• Effects of the hydroxyl radical and hydrogen peroxide on tooth bleaching.

  Journal of endodontics 20040101

• Potent bradykinin antagonists containing N-benzylglycine or N-benzyl-l-alanine in position 8.

  The journal of peptide research : official journal of the American Peptide Society 20040101

• Spinal phenotype of cerebrotendinous xanthomatosis--a pitfall in the diagnosis of multiple sclerosis.

  Journal of neurology 20040101

• Ammonium exposure and pyruvate affect the amino acid metabolism of bovine blastocysts in vitro.

  Reproduction (Cambridge, England) 20040101

• Conformational properties of N-acetyl-L-alanine N',N'-dimethylamide.

  Acta biochimica Polonica 20040101

• African sharptooth catfish Clarias gariepinus does not detoxify ammonia to urea or amino acids but actively excretes ammonia during exposure to environmental ammonia.

  Physiological and biochemical zoology : PBZ 20040101

• rBPI(10-193) is secreted by CHO cells and retains the activity of rBPI21.

  Journal of endotoxin research 20040101

• Glycoprotein IIb/IIIa inhibition enhances platelet nitric oxide release.

  Thrombosis research 20040101

• Congenital insensitivity to pain with anhidrosis in Taiwan: a morphometric and genetic study.

  European neurology 20040101

• Comparison of bioenergetic activity of primary porcine hepatocytes cultured in four different media.

  Cell transplantation 20040101

• Manganese superoxide dismutase Ala-9Val polymorphism and risk of breast cancer in a population-based case-control study of African Americans and whites.

  Breast cancer research : BCR 20040101

• A study of promoter and intronic markers of ApoI/Fas gene and the interaction with Fas ligand in relapsing multiple sclerosis.

  European neurology 20040101

• Role of diffusion-weighted imaging and in vivo proton magnetic resonance spectroscopy in the differential diagnosis of ring-enhancing intracranial cystic mass lesions.

  Journal of computer assisted tomography 20040101

• Two dialkoxynaphthalene aldehydes as backbone amide linkers for solid-phase synthesis.

  Journal of combinatorial chemistry 20040101

• Influence of environmental cues on transcriptional regulation of foo and clp coding for F165(1) and CS31A adhesins in Escherichia coli.

  Research in microbiology 20040101

• Status of methylthioadenosine phosphorylase and its impact on cellular response to L-alanosine and methylmercaptopurine riboside in human soft tissue sarcoma cells.

  Oncology research 20040101

• Alanine and TLD coupled detectors for fast neutron dose measurements in neutron capture therapy (NCT).

  Radiation protection dosimetry 20040101

• Identification of the 15FRFG domain in HIV-1 Gag p6 essential for Vpr packaging into the virion.

  Retrovirology 20040101

• Long-term follow-up of spontaneous development in a boy with familial male precocious puberty.

  Hormone research 20040101

• Novel troponin T mutation in familial dilated cardiomyopathy with gender-dependant severity.

  Molecular genetics and metabolism 20040101

• Involvement of proteases in glycosyltransferase secretion: Alzheimer's beta-secretase-dependent cleavage and a following processing by an aminopeptidase.

  Glycoconjugate journal 20040101

• Design, synthesis, and evaluation of peptides with estrogen-like activity.

  Biopolymers 20040101

• Genetic polymorphism in the manganese superoxide dismutase gene, antioxidant intake, and breast cancer risk: results from the Shanghai Breast Cancer Study.

  Breast cancer research : BCR 20040101

• Fas gene mutations in mycosis fungoides: analysis of laser capture-microdissected specimens from cutaneous lesions.

  Oncology 20040101

• [Stabilization of G x C-containing DNA duplexes by polyamides with parallel orientation in the minor groove].

  Bioorganicheskaia khimiia 20040101

• Safinamide: FCE 26743, NW 1015, PNU 151774, PNU 151774E.

  Drugs in R&D 20040101

• The frequency of alleles of the Pro12Ala polymorphism in PPARgamma2 is different between healthy controls and patients with type 2 diabetes.

  Folia biologica 20040101

• The alanine-rich heptad repeats are intact in the processed form of Plasmodium falciparum MSP3.

  Experimental parasitology 20040101

• [Synthesis and antiaggregative activity of a new RGDF mimetic].

  Bioorganicheskaia khimiia 20040101

• [Chemiluminescence of the polymorphonuclear leukocytes-luminol system in the presence of biogenic chloramines].

  Biofizika 20040101

• Factors affecting antimicrobial activity of Synechococcus leopoliensis.

  Microbiological research 20040101

• The sensitivity of yeast and yeast-like cells to new lysosomotropic agents.

  Cellular & molecular biology letters 20040101

• The aminoesters as inhibitors of plasma membrane H+-ATPase in the yeast Saccharomyces cerevisiae.

  Cellular & molecular biology letters 20040101

• Molecular characterization and diagnosis of Hb Crete [beta129(H7)Ala-->Pro].

  Hemoglobin 20040101

• Protective effect of intra-rectal administration of rebamipide on dextran sulfate sodium-induced rat colitis.

  Digestion 20040101

• Betulonic acid and derivatives, a new group of agents reducing side effects of cytostatics.

  Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20040101

• Development of a D-alanine sensor for the monitoring of a fermentation using the improved selectivity by the combination of D-amino acid oxidase and pyruvate oxidase.

  Biosensors & bioelectronics 20031230

• Secondary mutations M36I and A71V in the human immunodeficiency virus type 1 protease can provide an advantage for the emergence of the primary mutation D30N.

  Biochemistry 20031230

• Limited set of amino acid residues in a class Ia aminoacyl-tRNA synthetase is crucial for tRNA binding.

  Biochemistry 20031230

• Residue 219 impacts on the dynamics of the C-terminal region in glutathione transferase A1-1: implications for stability and catalytic and ligandin functions.

  Biochemistry 20031230

• Modification of activity and specificity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26 by engineering of its entrance tunnel.

  The Journal of biological chemistry 20031226

• An isolated class II aminoacyl-tRNA synthetase insertion domain is functional in amino acid editing.

  The Journal of biological chemistry 20031226

• Dynamic features of a heme delivery system for cytochrome C maturation.

  The Journal of biological chemistry 20031226

• Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol.

  The Journal of biological chemistry 20031226

• Michael addition of amines and thiols to dehydroalanine amides: a remarkable rate acceleration in water.

  The Journal of organic chemistry 20031226

• Effect of pH on the oxidation-reduction properties of thioredoxins.

  Biochemistry 20031223

• Novel sst(4)-selective somatostatin (SRIF) agonists. 2. Analogues with beta-methyl-3-(2-naphthyl)alanine substitutions at position 8.

  Journal of medicinal chemistry 20031218

• Investigation of neuraminidase-substrate recognition using molecular dynamics and free energy calculations.

  Journal of medicinal chemistry 20031218

• Characterization of a gamma-adaptin ear-binding motif in enthoprotin.

  FEBS letters 20031218

• Increased rigidity of domain structures enhances the stability of a mutant enzyme created by directed evolution.

  Biochemistry 20031216

• Thermodynamic cycle analysis and inhibitor design against beta-lactamase.

  Biochemistry 20031216

• Arg-14 loop of site 3 anemone toxins: effects of glycine replacement on toxin affinity.

  Biochemistry 20031216

• Induction of substrate specificity shifts by placement of alanine insertions within the consensus amphipathic region of the Escherichia coli GABA (gamma-aminobutyric acid) transporter encoded by gabP.

  The Biochemical journal 20031215

• Analysis of genetic variations of protein tyrosine kinase fyn and their association with alcohol dependence in two independent cohorts.

  Biological psychiatry 20031215

• Oligosaccharide-peptide ligation of glycosyl thiolates with dehydropeptides: synthesis of S-linked mucin-related glycopeptide conjugates.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20031215

• Gating of shaker-type channels requires the flexibility of S6 caused by prolines.

  The Journal of biological chemistry 20031212

• Human RNase H1 uses one tryptophan and two lysines to position the enzyme at the 3'-DNA/5'-RNA terminus of the heteroduplex substrate.

  The Journal of biological chemistry 20031212

• Group I metabotropic glutamate receptors bind to protein phosphatase 1C. Mapping and modeling of interacting sequences.

  The Journal of biological chemistry 20031212

• Role of disulfide bonds in Acrp30/adiponectin structure and signaling specificity. Different oligomers activate different signal transduction pathways.

  The Journal of biological chemistry 20031212

• pH-induced conformational changes of AcrA, the membrane fusion protein of Escherichia coli multidrug efflux system.

  The Journal of biological chemistry 20031212

• Fibronectin protects prostate cancer cells from tumor necrosis factor-alpha-induced apoptosis via the AKT/survivin pathway.

  The Journal of biological chemistry 20031212

• Beta-deuterium isotope effects on amine basicity, 'inductive' and stereochemical.

  Journal of the American Chemical Society 20031210

• Local destabilization of the tropomyosin coiled coil gives the molecular flexibility required for actin binding.

  Biochemistry 20031209

• Hydrogen bonding alteration of Thr-204 in the complex between pharaonis phoborhodopsin and its transducer protein.

  Biochemistry 20031209

• Inhibition of ubiquitin/proteasome-dependent proteolysis in Saccharomyces cerevisiae by a Gly-Ala repeat.

  FEBS letters 20031204

• Prediction of the binding site on E1 in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus.

  FEBS letters 20031204

• Identification of Tyr413 as an active site residue in the flavoprotein tryptophan 2-monooxygenase and analysis of its contribution to catalysis.

  Biochemistry 20031202

• Negative charge at amino acid 149 is the molecular determinant for substrate specificity of lecithin: cholesterol acyltransferase for phosphatidylcholine containing 20-carbon sn-2 fatty acyl chains.

  Biochemistry 20031202

• Core formation in Escherichia coli bacterioferritin requires a functional ferroxidase center.

  Biochemistry 20031202

• Amplification of diverse catalytic properties of evolving molecules in a simulated hydrothermal environment.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20031201

• Low-temperature Fourier transform infrared spectra and hydrogen bonding in polycrystalline L-alanine.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20031201

• MDR1 Ala893 polymorphism is associated with inflammatory bowel disease.

  American journal of human genetics 20031201

• NMR conformational studies of micelle-bound orexin-B: a neuropeptide involved in the sleep/awake cycle and feeding regulation.

  Journal of biomolecular structure & dynamics 20031201

• Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues.

  Analytical biochemistry 20031201

• Molecular characterization of D-amino acid oxidase from common carp Cyprinus carpio and its induction with exogenous free D-alanine.

  Archives of biochemistry and biophysics 20031201

• Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility.

  Nature immunology 20031201

• Outcome of liver transplantation for familial amyloidotic polyneuropathy.

  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20031201

• Double-stranded DNA-induced localized unfolding of HCV NS3 helicase subdomain 2.

  Protein science : a publication of the Protein Society 20031201

• The human peroxisome proliferator-activated receptor gamma2 (PPARgamma2) Pro12Ala polymorphism is associated with decreased risk of diabetic nephropathy in patients with type 2 diabetes.

  Diabetes 20031201

• Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase.

  The EMBO journal 20031201

• Effect of alanine energy response and phantom material on depth dose measurements in ocular proton beams.

  Technology in cancer research & treatment 20031201

• Identification of protein kinases responsible for phosphorylation of Epstein-Barr virus nuclear antigen leader protein at serine-35, which regulates its coactivator function.

  The Journal of general virology 20031201

• A comparative study of amino acid consumption by rat islet cells and the clonal beta-cell line BRIN-BD11 - the functional significance of L-alanine.

  The Journal of endocrinology 20031201

• Association of the (TAAAA)n repeat polymorphism in the sex hormone-binding globulin (SHBG) gene with polycystic ovary syndrome and relation to SHBG serum levels.

  The Journal of clinical endocrinology and metabolism 20031201

• Water polymers in L-alanyl-L-methionine hemihydrate.

  Acta crystallographica. Section C, Crystal structure communications 20031201

• Diadenosine tetraphosphate (Ap4A) induces a diabetogenic situation: its impact on blood glucose, plasma insulin, gluconeogenesis, glucose uptake and GLUT-4 transporters.

  Die Pharmazie 20031201

• Modulation of the positive inotropic effect of pyruvate by energetic substrate availability.

  Acta cardiologica 20031201

• Alcoholism-related phenotypes and genetic variants of the CB1 receptor.

  European archives of psychiatry and clinical neuroscience 20031201

• Glucose-deprivation-induced [3H]D-aspartate release from isolated bovine and human retinae.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20031201

• Identification of the catalytic nucleophile of the family 29 alpha-L-fucosidase from Thermotoga maritima through trapping of a covalent glycosyl-enzyme intermediate and mutagenesis.

  The Journal of biological chemistry 20031128

• Ser-64 and Ser-111 in PHAS-I are dispensable for insulin-stimulated dissociation from eIF4E.

  The Journal of biological chemistry 20031128

• Derivatized amino acids relevant to native peptide synthesis by chemical ligation and acyl transfer.

  The Journal of organic chemistry 20031128

• Synthesis of beta-cyclopropylalanines by photolysis of diacyl peroxides.

  Organic letters 20031127

• Presence of D-alanine in an endopeptidase from Streptococcus pyogenes.

  The Journal of biological chemistry 20031121

• DNA-PK phosphorylation sites in XRCC4 are not required for survival after radiation or for V(D)J recombination.

  DNA repair 20031121

• Hydrogen-bond cooperativity, vibrational coupling, and dependence of helix stability on changes in amino acid sequence in small 3 10-helical peptides. A density functional theory study.

  Journal of the American Chemical Society 20031119

• Histidine 61: an important heme ligand in the soluble fumarate reductase from Shewanella frigidimarina.

  Biochemistry 20031118

• Structural characterization of the peroxodiiron(III) intermediate generated during oxygen activation by the W48A/D84E variant of ribonucleotide reductase protein R2 from Escherichia coli.

  Biochemistry 20031118

• Glycosynthase activity of Bacillus licheniformis 1,3-1,4-beta-glucanase mutants: specificity, kinetics, and mechanism.

  Biochemistry 20031118

• N-terminal modifications increase the neutral-pH stability of pepsin.

  Biochemistry 20031118

• Functional analysis of a phosphatidic acid binding domain in human Raf-1 kinase: mutations in the phosphatidate binding domain lead to tail and trunk abnormalities in developing zebrafish embryos.

  The Journal of biological chemistry 20031114

• Determinants of binding affinity and specificity for the interaction of TEM-1 and SME-1 beta-lactamase with beta-lactamase inhibitory protein.

  The Journal of biological chemistry 20031114

• Identification of a novel TATA element-binding protein binding region at the N terminus of the Saccharomyces cerevisiae TAF1 protein.

  The Journal of biological chemistry 20031114

• Concerted motions of the integrin-binding loop and the C-terminal tail of the non-RGD disintegrin obtustatin.

  The Journal of biological chemistry 20031114

• Design of a partial peptide mimetic of anginex with antiangiogenic and anticancer activity.

  The Journal of biological chemistry 20031114

• Essential glycine in the proton channel of Escherichia coli transhydrogenase.

  The Journal of biological chemistry 20031114

• Exploration of the P6/P7 region of the peptide-binding site of the human class II major histocompatability complex protein HLA-DR1.

  The Journal of biological chemistry 20031107

• Mars-like soils in the Atacama Desert, Chile, and the dry limit of microbial life.

  Science (New York, N.Y.) 20031107

• Chemical and enzymatic synthesis of fluorinated-dehydroalanine-containing peptides.

  Chembiochem : a European journal of chemical biology 20031107

• Identification of the taste enhancer alapyridaine in beef broth and evaluation of its sensory impact by taste reconstitution experiments.

  Journal of agricultural and food chemistry 20031105

• Steroidogenic factor-1 and the gonadotrope-specific element enhance basal and pituitary adenylate cyclase-activating polypeptide-stimulated transcription of the human glycoprotein hormone alpha-subunit gene in gonadotropes.

  Molecular endocrinology (Baltimore, Md.) 20031101

• Protein kinase C and A sites on troponin I regulate myofilament Ca2+ sensitivity and ATPase activity in the mouse myocardium.

  The Journal of physiology 20031101

• Computational detection of the binding-site hot spot at the remodeled human growth hormone-receptor interface.

  Proteins 20031101

• Synthesis, structure analysis, solution chemistry, and in vitro insulinomimetic activity of novel oxovanadium(IV) complexes with tripodal ligands containing an imidazole group derived from amino acids.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20031101

• Isolation and anti-oomycete activity of nyasol from Anemarrhena asphodeloides rhizomes.

  Phytochemistry 20031101

• Oral glutamine attenuates surgical manipulation-induced alterations in the intestinal brush border membrane.

  The Journal of surgical research 20031101

• The Pro12Ala polymorphism of PPARgamma2 gene and susceptibility to type 2 diabetes mellitus in a Polish population.

  Diabetes research and clinical practice 20031101

• Role of backbone hydration and salt-bridge formation in stability of alpha-helix in solution.

  Biophysical journal 20031101

• Immunofocusing: antigen engineering to promote the induction of HIV-neutralizing antibodies.

  Trends in molecular medicine 20031101

• Bezafibrate induces a mitochondrial derangement in human cell lines: a PPAR-independent mechanism for a peroxisome proliferator.

  Chemical research in toxicology 20031101

• Mapping the binding domains on meningococcal Opa proteins for CEACAM1 and CEA receptors.

  Molecular microbiology 20031101

• A six amino acid deletion, partially overlapping the VanSB G2 ATP-binding motif, leads to constitutive glycopeptide resistance in VanB-type Enterococcus faecium.

  Molecular microbiology 20031101

• A decrease in glucose production is associated with an increase in plasma citrulline response to oral arginine in normal volunteers.

  Metabolism: clinical and experimental 20031101

• Stabilization of a chitinase from Serratia marcescens by Gly-->Ala and Xxx-->Pro mutations.

  Protein engineering 20031101

• Nitrogen starvation-induced changes in amino acid and free ammonium pools in Schizophyllum commune colonies.

  Current microbiology 20031101

• A novel missense mutation of the MEN1 gene in a multiple endocrine neoplasia type 1 patient associated with carcinoid syndrome.

  Internal medicine (Tokyo, Japan) 20031101

• [Studies on chemical constituents of the mycelia from fermented culture of Flammulina velutipes].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20031101

• Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I.

  The Journal of biological chemistry 20031031

• Molecular determinants of the balance between co-repressor and co-activator recruitment to the retinoic acid receptor.

  The Journal of biological chemistry 20031031

• Requirement of a Tha4-conserved transmembrane glutamate in thylakoid Tat translocase assembly revealed by biochemical complementation.

  The Journal of biological chemistry 20031031

• 2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding.

  Journal of molecular biology 20031031

• Chiral recognition of peptide enantiomers by cinchona alkaloid derived chiral selectors: mechanistic investigations by liquid chromatography, NMR spectroscopy, and molecular modeling.

  The Journal of organic chemistry 20031031

• Sequential and specific exchange of multiple coiled-coil components.

  Journal of the American Chemical Society 20031029

• Amersham Prize winner. Expanding the genetic code.

  Science (New York, N.Y.) 20031024

• Aqueous self-assembly of unsymmetric Peptide bolaamphiphiles into nanofibers with hydrophilic cores and surfaces.

  Journal of the American Chemical Society 20031022

• Presence of ferric hydroxide clusters in mutants of Haemophilus influenzae ferric ion-binding protein A.

  Biochemistry 20031021

• The association of cyclin A and cyclin kinase inhibitor p21 in response to gamma-irradiation requires the CDK2 binding region, but not the Cy motif.

  Biochimica et biophysica acta 20031021

• Complete alanine scanning of intersubunit interfaces in a foot-and-mouth disease virus capsid reveals critical contributions of many side chains to particle stability and viral function.

  The Journal of biological chemistry 20031017

• A novel gamma-hydroxybutyrate dehydrogenase: identification and expression of an Arabidopsis cDNA and potential role under oxygen deficiency.

  The Journal of biological chemistry 20031017

• Ligand-independent CXCR2 dimerization.

  The Journal of biological chemistry 20031017

• Targeting and assembly of mitochondrial tail-anchored protein Tom5 to the TOM complex depend on a signal distinct from that of tail-anchored proteins dispersed in the membrane.

  The Journal of biological chemistry 20031017

• Ebony, a novel nonribosomal peptide synthetase for beta-alanine conjugation with biogenic amines in Drosophila.

  The Journal of biological chemistry 20031017

• Protein-tyrosine phosphatase 1B mediates the effects of insulin on the actin cytoskeleton in immortalized fibroblasts.

  The Journal of biological chemistry 20031017

• The region between transmembrane domains 1 and 2 of the reduced folate carrier forms part of the substrate-binding pocket.

  The Journal of biological chemistry 20031017

• Synthesis of orthogonally protected lanthionines.

  The Journal of organic chemistry 20031017

• Synthesis of a cyclic peptide containing norlanthionine: effect of the thioether bridge on peptide conformation.

  The Journal of organic chemistry 20031017

• A 'dock, lock, and latch' structural model for a staphylococcal adhesin binding to fibrinogen.

  Cell 20031017

• Bcl-2 expression using retrograde transport of adenoviral vectors inhibits cytochrome c-release and caspase-1 activation in motor neurons of mutant superoxide dismutase 1 (G93A) transgenic mice.

  Neuroscience letters 20031016

• Apolipoprotein E -491 promoter polymorphism is an independent risk factor for Alzheimer's disease in the Chinese population.

  Neuroscience letters 20031016

• Tumour necrosis factor-alpha gene polymorphisms and Alzheimer's disease.

  Neuroscience letters 20031016

• The human SUMF1 gene, required for posttranslational sulfatase modification, defines a new gene family which is conserved from pro- to eukaryotes.

  Gene 20031016

• Two alanines juxtaposed to aggrecan's G1 domain alter its intracellular localization.

  Journal of cellular biochemistry 20031015

• Analysis of proton-proton transfer dynamics in rotating solids and their use for 3D structure determination.

  Journal of the American Chemical Society 20031015

• Energetics of sequence-specific protein-DNA association: computational analysis of integrase Tn916 binding to its target DNA.

  Biochemistry 20031014

• Relaxing the nicotinamide cofactor specificity of phosphite dehydrogenase by rational design.

  Biochemistry 20031014

• Patients with severe muscle wasting are prone to develop hypoglycemia during fasting.

  Neurology 20031014

• Biomimetic studies on the mechanism of stereoselective lanthionine formation.

  Organic & biomolecular chemistry 20031007

• The three-dimensional structure of the liver X receptor beta reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligands.

  The Journal of biological chemistry 20031003

• Rim, a component of the presynaptic active zone and modulator of exocytosis, binds 14-3-3 through its N terminus.

  The Journal of biological chemistry 20031003

• Inhibition of glutamine synthetase in the mouse kidney: a novel mechanism of adaptation to metabolic acidosis.

  The Journal of biological chemistry 20031003

• Biogenesis of Fe-S cluster by the bacterial Suf system: SufS and SufE form a new type of cysteine desulfurase.

  The Journal of biological chemistry 20031003

• Inhibition of willardiine-induced currents through rat GluR6/KA-2 kainate receptor channels by Zinc and other divalent cations.

  Neuroscience letters 20031002

• Post-translational incorporation of the antiproliferative agent azatyrosine into the C-terminus of alpha-tubulin.

  The Biochemical journal 20031001

• Effect of carbohydrate moieties on the folate hydrolysis activity of the prostate specific membrane antigen.

  The Prostate 20031001

• Identification of two novel mutations of IRF6 in Korean families affected with Van der Woude syndrome.

  International journal of molecular medicine 20031001

• Enteral alanyl-glutamine supplement promotes intestinal adaptation in rats.

  International journal of molecular medicine 20031001

• Glutamine efflux from astrocytes is mediated by multiple pathways.

  Journal of neurochemistry 20031001

• The A54T polymorphism of fatty acid-binding protein 2 may entail a reduction in fat-stimulated secretion of GIP that potentiates the adverse impact of fatty diets on insulin sensitivity.

  Medical hypotheses 20031001

• Contribution of wild-type transthyretin to hereditary peripheral nerve amyloid.

  Muscle & nerve 20031001

• Improvement of resolution in solid state NMR spectra with J-decoupling: an analysis of lineshape contributions in uniformly 13C-enriched amino acids and proteins.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20031001

• Prospective study of the association between the proline to alanine codon 12 polymorphism in the PPARgamma gene and type 2 diabetes.

  Diabetes care 20031001

• Molecular dynamics studies of alanine racemase: a structural model for drug design.

  Biopolymers 20031001

• L-methionyl-L-alanine: a dipeptide with hexagonal symmetry and Z' = 7.

  Acta crystallographica. Section C, Crystal structure communications 20031001

• Genetic modulation of PPARgamma phosphorylation regulates insulin sensitivity.

  Developmental cell 20031001

• Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: a meta-analysis.

  Journal of medical genetics 20031001

• Effects of phosphodiesterase 3,4,5 inhibitors on hepatocyte cAMP levels, glycogenolysis, gluconeogenesis and susceptibility to a mitochondrial toxin.

  Molecular and cellular biochemistry 20031001

• The association of Pro12Ala polymorphism in PPARgamma2 with lower carotid artery IMT in Japanese.

  Diabetes research and clinical practice 20031001

• Investigation of diffraction line broadening due to compositional fluctuations in L-alanine-doped triglycine sulfate.

  Acta crystallographica. Section B, Structural science 20031001

• Mutagenesis of the dimer interface region of Corynebacterium callunae starch phosphorylase perturbs the phosphate-dependent conformational relay that enhances oligomeric stability of the enzyme.

  Journal of biochemistry 20031001

• Distribution and pharmacology of alanine-serine-cysteine transporter 1 (asc-1) in rodent brain.

  The European journal of neuroscience 20031001

• Effect of four-alpha-helix bundle cavity size on volatile anesthetic binding energetics.

  Biochemistry 20030930

• Effect of proline to alanine mutation on the thermal stability of the all-beta-sheet protein tendamistat.

  Biochimica et biophysica acta 20030923

• Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1.

  The Journal of biological chemistry 20030919

• Contributions of CDR3 to V H H domain stability and the design of monobody scaffolds for naive antibody libraries.

  Journal of molecular biology 20030919

• Cell surface labeling of Escherichia coli via copper(I)-catalyzed [3+2] cycloaddition.

  Journal of the American Chemical Society 20030917

• Investigation of an LDLR gene polymorphism (19p13.2) in susceptibility to migraine without aura.

  Journal of the neurological sciences 20030915

• Experimental evidence for lack of homodimerization of the G protein-coupled human N-formyl peptide receptor.

  Journal of immunology (Baltimore, Md. : 1950) 20030915

• Stimulation by surangin B of endogenous amino acid release from synaptosomes.

  Toxicon : official journal of the International Society on Toxinology 20030915

• Kennedy's disease. Phosphorylation of the polyglutamine-expanded form of androgen receptor regulates its cleavage by caspase-3 and enhances cell death.

  The Journal of biological chemistry 20030912

• Effects of the substitution of Phe4 in the opioid peptide [D-Ala8]dynorphin A-(1-11)NH2.

  Journal of medicinal chemistry 20030911

• 2-D array formation of genetically engineered viral cages on au surfaces and imaging by atomic force microscopy.

  Journal of the American Chemical Society 20030910

• MnSOD polymorphism and breast cancer in a population-based case-control study.

  Cancer letters 20030910

• Methylenetetrahydrofolate reductase gene polymorphisms in patients with schizophrenia.

  Brain research. Molecular brain research 20030910

• Structural study of melanocortin peptides by fluorescence spectroscopy: identification of beta-(2-naphthyl)-D-alanine as a fluorescent probe.

  Biochimica et biophysica acta 20030908

• Mutational, structural, and kinetic studies of the ATP-binding site of Methanobacterium thermoautotrophicum nicotinamide mononucleotide adenylyltransferase.

  The Journal of biological chemistry 20030905

• Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA.

  The Journal of biological chemistry 20030905

• Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61).

  The Journal of biological chemistry 20030905

• A single amino acid change (substitution of the conserved Glu-590 with alanine) in the C-terminal domain of rat liver carnitine palmitoyltransferase I increases its malonyl-CoA sensitivity close to that observed with the muscle isoform of the enzyme.

  The Journal of biological chemistry 20030905

• Atypical recognition consensus of CIN85/SETA/Ruk SH3 domains revealed by target-assisted iterative screening.

  The Journal of biological chemistry 20030905

• Brief total synthesis of the cell cycle inhibitor tryprostatin B and related preparation of its alanine analogue.

  The Journal of organic chemistry 20030905

• On the structural and functional importance of the highly conserved Glu56 of Thermus thermophilus L4 ribosomal protein.

  Journal of molecular biology 20030905

• The functional binding epitope of a high affinity variant of human growth hormone mapped by shotgun alanine-scanning mutagenesis: insights into the mechanisms responsible for improved affinity.

  Journal of molecular biology 20030905

• High tumorigenic potential of a constitutively active mutant of the cholecystokinin 2 receptor.

  Oncogene 20030904

• Probing helix formation in unsolvated peptides.

  Journal of the American Chemical Society 20030903

• Structural and functional study of the apelin-13 peptide, an endogenous ligand of the HIV-1 coreceptor, APJ.

  Biochemistry 20030902

• Mutation of proline residues in the NH(2)-terminal region of the multidrug resistance protein, MRP1 (ABCC1): effects on protein expression, membrane localization, and transport function.

  Biochimica et biophysica acta 20030902

• MICA association with presumed ocular histoplasmosis syndrome (POHS).

  Molecular vision 20030902

• Novel Cu(II)-quinoline carboxamide complexes: structural characterization, cytotoxicity and reactivity towards 5'-GMP.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20030901

• Glucagon's actions are modified by the combination of epinephrine and gluconeogenic precursor infusion.

  American journal of physiology. Endocrinology and metabolism 20030901

• Short-term training attenuates muscle TCA cycle expansion during exercise in women.

  Journal of applied physiology (Bethesda, Md. : 1985) 20030901

• The role of two novel regulatory sites in the activation of the cGMP-dependent protein kinase from Plasmodium falciparum.

  The Biochemical journal 20030901

• The mouse Chrna4 A529T polymorphism alters the ratio of high to low affinity alpha 4 beta 2 nAChRs.

  Neuropharmacology 20030901

• MELAS: clinical phenotype and morphological brain abnormalities.

  Acta neuropathologica 20030901

• MHC recognition by hapten-specific HLA-A2-restricted CD8+ CTL.

  Journal of immunology (Baltimore, Md. : 1950) 20030901

• Epitope-enhanced conserved HIV-1 peptide protects HLA-A2-transgenic mice against virus expressing HIV-1 antigen.

  Journal of immunology (Baltimore, Md. : 1950) 20030901

• Site2 binding energetics of the regulatory step of growth hormone-induced receptor homodimerization.

  Protein science : a publication of the Protein Society 20030901

• Heteronuclear dipolar recoupling in liquid crystals and solids by PISEMA-type pulse sequences.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20030901

• Spin-state selection in solid-state NMR.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20030901

• Free radical scavenger effect of rebamipide in sperm processing and cryopreservation.

  Asian journal of andrology 20030901

• Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating.

  The Journal of general physiology 20030901

• Apocalmodulin and Ca2+ calmodulin-binding sites on the CaV1.2 channel.

  Biophysical journal 20030901

• The distribution of lipid attached spin probes in bilayers: application to membrane protein topology.

  Biophysical journal 20030901

• Low-frequency modes of peptides and globular proteins in solution observed by ultrafast OHD-RIKES spectroscopy.

  Biophysical journal 20030901

• Effects of hypothermia on brain glucose metabolism in acute liver failure: a H/C-nuclear magnetic resonance study.

  Gastroenterology 20030901

• Inhibition of tumor cell-induced platelet aggregation and lung metastasis by the oral GpIIb/IIIa antagonist XV454.

  Thrombosis and haemostasis 20030901

• A reduced extracellular serotonin level increases the 5-HT1A PET ligand 18F-MPPF binding in the rat hippocampus.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030901

• Regulation of D-amino acid oxidase expression in the yeast Rhodotorula gracilis.

  Yeast (Chichester, England) 20030901

• Correlation of structure and vibrational spectra of the zwitterion L-alanine in the presence of water: an experimental and density functional analysis.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030901

• A rare Cu/Zn superoxide dismutase mutation causing familial amyotrophic lateral sclerosis with variable age of onset, incomplete penetrance and a sensory neuropathy.

  Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20030901

• Gas-phase investigation of Pd(II)-alanine complexes with small native and derivatized peptides containing histidine.

  Journal of mass spectrometry : JMS 20030901

• The serotonin precursor 5-hydroxytryptophan delays neuromuscular disease in murine familial amyotrophic lateral sclerosis.

  Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20030901

• Fasidotril Eli Lilly.

  Current opinion in investigational drugs (London, England : 2000) 20030901

• Effect on T cell recognition and immunogenicity of alanine-substituted peptides corresponding to 97-116 sequence of the rat AChR alpha-subunit.

  Annals of the New York Academy of Sciences 20030901

• Multinuclear NMR investigations on the metabolic recovery of the isolated perfused mouse liver after cold preservation.

  Biochimie 20030901

• Human rhinovirus 2 2Apro recognition of eukaryotic initiation factor 4GI. Involvement of an exosite.

  The Journal of biological chemistry 20030829

• Energetic contribution of residues in the Runx1 Runt domain to DNA binding.

  The Journal of biological chemistry 20030829

• Mutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunit.

  The Journal of biological chemistry 20030829

• Modification of CCAAT/enhancer-binding protein-beta by the small ubiquitin-like modifier (SUMO) family members, SUMO-2 and SUMO-3.

  The Journal of biological chemistry 20030829

• Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2.

  The Journal of biological chemistry 20030829

• Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function.

  The Journal of biological chemistry 20030829

• Fluorescent caged phosphoserine peptides as probes to investigate phosphorylation-dependent protein associations.

  Journal of the American Chemical Society 20030827

• Structures of phage-display peptides that bind to the malarial surface protein, apical membrane antigen 1, and block erythrocyte invasion.

  Biochemistry 20030826

• Effect of diet on exercise tolerance in carnitine palmitoyltransferase II deficiency.

  Neurology 20030826

• Nature of the reactants and influence of water on the supramolecular assembly.

  Inorganic chemistry 20030825

• Structure, stability, and function of hDim1 investigated by NMR, circular dichroism, and mutational analysis.

  Biochemistry 20030819

• Alanine-scanning mutations in domain 4 of anthrax toxin protective antigen reveal residues important for binding to the cellular receptor and to a neutralizing monoclonal antibody.

  The Journal of biological chemistry 20030815

• Novel inhibitor for prolyl aminopeptidase from Serratia marcescens and studies on the mechanism of substrate recognition of the enzyme using the inhibitor.

  Archives of biochemistry and biophysics 20030815

• Identification of gene expression profiles predicting tumor cell response to L-alanosine.

  Biochemical pharmacology 20030815

• Sequential recognition of two distinct sites in sigma(S) by the proteolytic targeting factor RssB and ClpX.

  The EMBO journal 20030815

• Complexation of several fungicides with beta-cyclodextrin: determination of the association constants and isolation of the solid complexes.

  Journal of agricultural and food chemistry 20030813

• Glycine facilitates transmitter release at developing synapses: a patch clamp study from Purkinje neurons of the newborn rat.

  Brain research. Developmental brain research 20030812

• Complex with a phage display-derived peptide provides insight into the function of insulin-like growth factor I.

  Biochemistry 20030812

• Sequence gamma 377-395(P2), but not gamma 190-202(P1), is the binding site for the alpha MI-domain of integrin alpha M beta 2 in the gamma C-domain of fibrinogen.

  Biochemistry 20030812

• Phosphorylation at serine 75 is required for UV-mediated degradation of human Cdc25A phosphatase at the S-phase checkpoint.

  The Journal of biological chemistry 20030808

• How hydrophobic is alanine?

  The Journal of biological chemistry 20030808

• Mutational analysis of bacteriophage T4 RNA ligase 1. Different functional groups are required for the nucleotidyl transfer and phosphodiester bond formation steps of the ligation reaction.

  The Journal of biological chemistry 20030808

• Asp274 and his346 are essential for heme binding and catalytic function of human indoleamine 2,3-dioxygenase.

  The Journal of biological chemistry 20030808

• Structural basis of Synercid (quinupristin-dalfopristin) resistance in Gram-positive bacterial pathogens.

  The Journal of biological chemistry 20030808

• Negative charge at the consensus sequence for the serum- and glucocorticoid-inducible kinase, SGK1, determines pH sensitivity of the renal outer medullary K+ channel, ROMK1.

  Biochemical and biophysical research communications 20030808

• The tRNA-like domains of E coli and A.aeolicus transfer-messenger RNA: structural and functional studies.

  Journal of molecular biology 20030808

• Localization of a substrate binding site on the FeMo-cofactor in nitrogenase: trapping propargyl alcohol with an alpha-70-substituted MoFe protein.

  Biochemistry 20030805

• Peristalsis regulation by tachykinin NK1 receptors in the rabbit isolated distal colon.

  American journal of physiology. Gastrointestinal and liver physiology 20030801

• Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1.

  The Journal of biological chemistry 20030801

• Determination of D- and L-alanine concentrations using a pyruvic acid sensor.

  Biosensors & bioelectronics 20030801

• Dietary protein reduction in sheep and goats: different effects on L-alanine and L-leucine transport across the brush-border membrane of jejunal enterocytes.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20030801

• Mutational analysis of the human FATE gene in 144 infertile men.

  Human genetics 20030801

• Exercise and recovery metabolism in the Pacific spiny dogfish (Squalus acanthias).

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20030801

• Oncogenic mutations and packing defects in protein structure.

  Journal of biomolecular structure & dynamics 20030801

• Protein stability and plasticity of the hydrophobic cavity in wheat ns-LTP.

  Journal of biomolecular structure & dynamics 20030801

• Key roles of Phe1112 and Ser1115 in the pore-forming IIIS5-S6 linker of L-type Ca2+ channel alpha1C subunit (CaV 1.2) in binding of dihydropyridines and action of Ca2+ channel agonists.

  Molecular pharmacology 20030801

• Structural basis for partial agonist action at ionotropic glutamate receptors.

  Nature neuroscience 20030801

• Evaluation of the AccuTnI cardiac troponin I assay for risk assessment in acute coronary syndromes.

  Clinical chemistry 20030801

• Interaction of insulin and prior exercise in control of hepatic metabolism of a glucose load.

  Diabetes 20030801

• Effects of chronic lithium and sodium valproate on concentrations of brain amino acids.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20030801

• Development and characterization of a highly selective neuropeptide Y Y5 receptor agonist radioligand: [125I][hPP1-17, Ala31, Aib32]NPY.

  British journal of pharmacology 20030801

• Alanine administration does not stimulate gluconeogenesis in preterm infants.

  Metabolism: clinical and experimental 20030801

• L-Serine, D- and L-proline and alanine as respiratory substrates of Helicobacter pylori: correlation between in vitro and in vivo amino acid levels.

  Microbiology (Reading, England) 20030801

• The synthesis of isoquinoline alkaloid and its related compounds using alanine derivatives as chiral auxiliaries.

  Chemical & pharmaceutical bulletin 20030801

• Identification of novel histone post-translational modifications by peptide mass fingerprinting.

  Chromosoma 20030801

• The Ala45Thr polymorphism of BETA2/NeuroD1 gene and susceptibility to type 1 diabetes mellitus in caucasians.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20030801

• Radical scavengers for Ménière's disease after failure of conventional therapy: a pilot study.

  Acta oto-laryngologica 20030801

• Carbendazim and metalaxyl residues in post-harvest treated apples.

  Food additives and contaminants 20030801

• The SAAP force field. A simple approach to a new all-atom protein force field by using single amino acid potential (SAAP) functions in various solvents.

  Journal of computational chemistry 20030730

• Direct probing of zwitterion formation in unsolvated peptides.

  Journal of the American Chemical Society 20030730

• NMR and CD spectroscopy show that imino acid restriction of the unfolded state leads to efficient folding.

  Biochemistry 20030729

• Surface salt bridges modulate DNA wrapping by the type II DNA-binding protein TF1.

  Biochemistry 20030729

• A peptide motif consisting of glycine, alanine, and valine is required for the fibrillization and cytotoxicity of human alpha-synuclein.

  Biochemistry 20030729

• Natural disulfide bond-disrupted mutants of AVR4 of the tomato pathogen Cladosporium fulvum are sensitive to proteolysis, circumvent Cf-4-mediated resistance, but retain their chitin binding ability.

  The Journal of biological chemistry 20030725

• Central role of a serine phosphorylation site within duck hepatitis B virus core protein for capsid trafficking and genome release.

  The Journal of biological chemistry 20030725

• Thermodynamic dissection of a low affinity protein-protein interface involved in human immunodeficiency virus assembly.

  The Journal of biological chemistry 20030725

• NMR-spectroscopic mapping of an engineered cavity in the I14A mutant of HPr from Staphylococcus carnosus using xenon.

  Journal of the American Chemical Society 20030723

• D-Ala-D-lac binding is not required for the high activity of vancomycin dimers against vancomycin resistant enterococci.

  Journal of the American Chemical Society 20030723

• Methionine synthase polymorphism is a risk factor for Alzheimer disease.

  Neuroreport 20030718

• A quantitative structure-activity relationship study on Clostridium histolyticum collagenase inhibitors: roles of electrotopological state indices.

  Bioorganic & medicinal chemistry 20030717

• Activity-dependent remodeling of presynaptic inputs by postsynaptic expression of activated CaMKII.

  Neuron 20030717

• Peptide models. XXXIII. Extrapolation of low-level Hartree-Fock data of peptide conformation to large basis set SCF, MP2, DFT, and CCSD(T) results. The Ramachandran surface of alanine dipeptide computed at various levels of theory.

  Journal of computational chemistry 20030715

• Protein and gene analyses of dysferlinopathy in a large group of Japanese muscular dystrophy patients.

  Journal of the neurological sciences 20030715

• First case of a single heterozygote of an abnormal hemoglobin, Hb Stanmore, [beta111(G13)Val-->Ala].

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030715

• Ras-induced serine phosphorylation of the focal adhesion protein paxillin is mediated by the Raf-->MEK-->ERK pathway.

  Experimental cell research 20030715

• Stalk region of beta-chain enhances the coreceptor function of CD8.

  Journal of immunology (Baltimore, Md. : 1950) 20030715

• Identification and characterization of a novel p300-mediated p53 acetylation site, lysine 305.

  The Journal of biological chemistry 20030711

• Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications.

  Journal of molecular biology 20030711

• The pentapeptide GGAGG has PII conformation.

  Journal of the American Chemical Society 20030709

• Histamine-releasing activity and binding to the FcepsilonRI alpha human mast cell receptor subunit of mast cell degranulating peptide analogues with alanine substitutions.

  Journal of medicinal chemistry 20030703

• Racemic and enantiopure synthesis and physicochemical characterization of the novel taste enhancer N-(1-carboxyethyl)-6-(hydroxymethyl)pyridinium-3-ol inner salt.

  Journal of agricultural and food chemistry 20030702

• Sub-cellular pathology of scrapie: coated pits are increased in PrP codon 136 alanine homozygous scrapie-affected sheep.

  Acta neuropathologica 20030701

• ABCA1 gene polymorphisms and their associations with coronary artery disease and plasma lipids in males from three ethnic populations in Singapore.

  Human genetics 20030701

• In vivo alanine/EPR dosimetry in daily clinical practice: a feasibility study.

  International journal of radiation oncology, biology, physics 20030701

• Differential modulation of glucose, lactate, and pyruvate oxidation by insulin and dichloroacetate in the rat heart.

  American journal of physiology. Heart and circulatory physiology 20030701

• Neurexin mediates the assembly of presynaptic terminals.

  Nature neuroscience 20030701

• Embolisation of intracranial meningiomas without subsequent surgery.

  Neuroradiology 20030701

• Determination of radical yields in solid-state drugs as one technique to identify drugs that will withstand radiosterilization: radioresistance of beta blockers.

  Radiation research 20030701

• Cytoprotective effects of rebamipide and carteolol hydrochloride against ultraviolet B-induced corneal damage in mice.

  Investigative ophthalmology & visual science 20030701

• Group I mGluR ligands fail to affect 6-hydroxydopamine- induced death and glutamate release of PC12 cells.

  Acta pharmacologica Sinica 20030701

• Experimental aspects of proton NMR spectroscopy in solids using phase-modulated homonuclear dipolar decoupling.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20030701

• Effects of pH and molecular charge on dipolar coupling interactions of solutes in skeletal muscle observed by DQF, 1H NMR spectroscopy.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20030701

• REDOR with a relative full-echo reference.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20030701

• Rotational-echo double resonance of uniformly labeled 13C clusters.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20030701

• Autoinhibition of Bcr-Abl through its SH3 domain.

  Molecular cell 20030701

• Conversion of the cleavage specificity of subtilisin YaB on oxidized insulin chains to an elastase-like specificity by replacement of Gly124 with Ala.

  Bioscience, biotechnology, and biochemistry 20030701

• Comparison of the effects of rebamipide with those of cimetidine on chronic gastritis associated with Helicobacter pylori in Mongolian gerbils.

  Alimentary pharmacology & therapeutics 20030701

• Review article: the role of rebamipide in the management of inflammatory disease of the gastrointestinal tract.

  Alimentary pharmacology & therapeutics 20030701

• Effect of long-term administration of rebamipide on Helicobacter pylori infection in mice.

  Alimentary pharmacology & therapeutics 20030701

• The effect of rebamipide on the expression of proinflammatory mediators and apoptosis in human neutrophils by Helicobacter pylori water-soluble surface proteins.

  Alimentary pharmacology & therapeutics 20030701

• Review article: rebamipide and the digestive epithelial barrier.

  Alimentary pharmacology & therapeutics 20030701

• The effect of rebamipide on Helicobacter pylori extract-mediated changes of gene expression in gastric epithelial cells.

  Alimentary pharmacology & therapeutics 20030701

• Rebamipide binds to iNOS-positive cells in acetic acid-treated but not in ethanol-treated rat gastric mucosa.

  Alimentary pharmacology & therapeutics 20030701

• The specific expression of hypoxia inducible factor-1alpha in human gastric mucosa induced by nonsteroidal anti-inflammatory drugs.

  Alimentary pharmacology & therapeutics 20030701

• Interaction of leptin with gastric myofibroblast transdifferentiation in Helicobacter pylori-infected Mongolian gerbils: the effect of rebamipide.

  Alimentary pharmacology & therapeutics 20030701

• Expression of midkine and receptor-like protein tyrosine phosphatase (RPTP)-beta genes in the rat stomach and the influence of rebamipide.

  Alimentary pharmacology & therapeutics 20030701

• Effect of rebamipide on prostaglandin receptors-mediated increase of inflammatory cytokine production by macrophages.

  Alimentary pharmacology & therapeutics 20030701

• Gastric restitution is inhibited by dexamethasone, which is reversed by hepatocyte growth factor and rebamipide.

  Alimentary pharmacology & therapeutics 20030701

• The protective effect of rebamipide on paracellular permeability of rat gastric epithelial cells.

  Alimentary pharmacology & therapeutics 20030701

• Effects of antioxidative agents on apoptosis induced by ischaemia-reperfusion in rat intestinal mucosa.

  Alimentary pharmacology & therapeutics 20030701

• Effects of rebamipide, a gastro-protective drug on the Helicobacter pylori status and inflammation in the gastric mucosa of patients with gastric ulcer: a randomized double-blind placebo-controlled multicentre trial.

  Alimentary pharmacology & therapeutics 20030701

• Review article: clinical significance of mucosal-protective agents: acid, inflammation, carcinogenesis and rebamipide.

  Alimentary pharmacology & therapeutics 20030701

• Effective pair potentials between protein amino acids.

  Physical review. E, Statistical, nonlinear, and soft matter physics 20030701

• Indole can act as an extracellular signal to regulate biofilm formation of Escherichia coli and other indole-producing bacteria.

  Canadian journal of microbiology 20030701

• Stereocontrolled synthesis of 3-(trans-2-aminocyclopropyl)alanine, a key component of belactosin A.

  Organic letters 20030626

• [Effects of alpha-methyl-(4-tetrazolyl-phenyl) glycine on the induction of hippocampal ischemic tolerance in the rat].

  Sheng li xue bao : [Acta physiologica Sinica] 20030625

• Conversion of cyclodextrin glycosyltransferase into a starch hydrolase by directed evolution: the role of alanine 230 in acceptor subsite +1.

  Biochemistry 20030624

• Structure of the O-polysaccharide of Proteus vulgaris O44: a new O-antigen that contains an amide of D-glucuronic acid with L-alanine.

  Carbohydrate research 20030623

• An investigation of the photon energy dependence of the EPR alanine dosimetry system.

  Physics in medicine and biology 20030621

• Analysis of the role of the EnvZ linker region in signal transduction using a chimeric Tar/EnvZ receptor protein, Tez1.

  The Journal of biological chemistry 20030620

• Identification of the nuclear localization signal of human immunodeficiency virus type 2 Vpx.

  Virology 20030620

• Evidence linking the Pseudomonas oleovorans alkane omega-hydroxylase, an integral membrane diiron enzyme, and the fatty acid desaturase family.

  FEBS letters 20030619

• Synthesis of [L-Ala-1]RA-VII, [D-Ala-2]RA-VII, and [D-Ala-4]RA-VII by epimerization of RA-VII, an antitumor bicyclic hexapeptide from Rubia plants, through oxazoles.

  Journal of the American Chemical Society 20030618

• A study of homonuclear dipolar recoupling pulse sequences in solid-state nuclear magnetic resonance.

  Journal of the American Chemical Society 20030618

• Electron transfer through a prenucleated bimetalated alanine-based peptide helix.

  Inorganic chemistry 20030616

• Apolipoprotein E, angiotensin-converting enzyme and alpha-1-antichymotrypsin genotypes are not associated with post-stroke dementia.

  Journal of the neurological sciences 20030615

• Open space swimming test to index antidepressant activity.

  Journal of neuroscience methods 20030615

• Exploring the effects of methylenetetrahydrofolate reductase gene variants C677T and A1298C on the risk of orofacial clefts in 261 Norwegian case-parent triads.

  American journal of epidemiology 20030615

• Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium.

  Cancer research 20030615

• Enantioselective degradation of metalaxyl in soils: chiral preference changes with soil pH.

  Environmental science & technology 20030615

• Binding of peptides with basic and aromatic residues to bilayer membranes: phenylalanine in the myristoylated alanine-rich C kinase substrate effector domain penetrates into the hydrophobic core of the bilayer.

  The Journal of biological chemistry 20030613

• Experimental tests of villin subdomain folding simulations.

  Journal of molecular biology 20030613

• Characterization of supramolecular (H2O)18 water morphology and water-methanol (H2O)15(CH3OH)3 clusters in a novel phosphorus functionalized trimeric amino acid host.

  Journal of the American Chemical Society 20030611

• The crystal structure, mutagenesis, and activity studies reveal that patatin is a lipid acyl hydrolase with a Ser-Asp catalytic dyad.

  Biochemistry 20030610

• The AMPA receptor antagonist NBQX prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis.

  Neuroscience letters 20030605

• Benzoylalanine-derived ketoamides carrying vinylbenzyl amino residues: discovery of potent water-soluble calpain inhibitors with oral bioavailability.

  Journal of medicinal chemistry 20030605

• Conserved hydrophobicity in the SH2-kinase linker is required for catalytic activity of Csk and CHK.

  FEBS letters 20030605

• Substitutions in the Escherichia coli RNA polymerase sigma70 factor that affect recognition of extended -10 elements at promoters.

  FEBS letters 20030605

• ELAC2/HPC2 polymorphisms, prostate-specific antigen levels, and prostate cancer.

  Journal of the National Cancer Institute 20030604

• Autophosphorylation of threonine 485 in the activation loop is essential for attaining eIF2alpha kinase activity of HRI.

  Biochemistry 20030603

• Kinetic mechanism of the GCN5-related chromosomal aminoglycoside acetyltransferase AAC(6')-Ii from Enterococcus faecium: evidence of dimer subunit cooperativity.

  Biochemistry 20030603

• Antifungal activity of a Candida albicans GGTase I inhibitor-alanine conjugate. Inhibition of Rho1p prenylation in C. albicans.

  Bioorganic & medicinal chemistry letters 20030602

• Ligand-selective activation of mu-oid receptor: demonstrated with deletion and single amino acid mutations of third intracellular loop domain.

  The Journal of pharmacology and experimental therapeutics 20030601

• Calculated gas-phase infrared spectra of imidazo[1,2-a]pyrazinediones derived from alanine.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030601

• Substitution of cysteine for selenocysteine in the catalytic center of type III iodothyronine deiodinase reduces catalytic efficiency and alters substrate preference.

  Endocrinology 20030601

• Nutritional benefits of enteral alanyl-glutamine supplementation on rat small intestinal damage induced by cyclophosphamide.

  Journal of gastroenterology and hepatology 20030601

• Genetics of familial amyloidotic polyneuropathy in a Hong Kong Chinese kindred.

  Acta neurologica Scandinavica 20030601

• MG2 and lactoferrin form a heterotypic complex in salivary secretions.

  Journal of dental research 20030601

• Dual phosphorylation controls Cdc25 phosphatases and mitotic entry.

  Nature cell biology 20030601

• Expression of Pseudomonas stutzeri Zobell cytochrome c-551 and its H47A variant in Escherichia coli.

  Protein expression and purification 20030601

• Loss of selenium from selenoproteins: conversion of selenocysteine to dehydroalanine in vitro.

  Journal of the American Society for Mass Spectrometry 20030601

• Polymorphisms in thyroid hormone pathway genes are associated with plasma TSH and iodothyronine levels in healthy subjects.

  The Journal of clinical endocrinology and metabolism 20030601

• Degradation, cyclic adenosine monophosphate production, insulin secretion, and glycemic effects of two novel N-terminal Ala2-substituted analogs of glucose-dependent insulinotropic polypeptide with preserved biological activity in vivo.

  Metabolism: clinical and experimental 20030601

• Increased insulin clearance in peroxisome proliferator-activated receptor gamma2 Pro12Ala.

  Metabolism: clinical and experimental 20030601

• Association between the Ala379Val variant of the lipoprotein associated phospholipase A2 and risk of myocardial infarction in the north and south of Europe.

  Atherosclerosis 20030601

• Proline can be utilized as an energy substrate during flight of Aedes aegypti females.

  Journal of insect physiology 20030601

• Enhanced triple-quantum excitation in 13C magic-angle spinning NMR.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20030601

• Enhanced energy metabolism during cold hypoxic organ preservation: studies on rat liver after pyruvate supplementation.

  Cryobiology 20030601

• Functional interaction between RNA polymerase alpha subunit C-terminal domain and sigma70 in UP-element- and activator-dependent transcription.

  Molecular cell 20030601

• Alanine prevents the inhibition of pyruvate kinase activity caused by tryptophan in cerebral cortex of rats.

  Metabolic brain disease 20030601

• (+)-(S)-alapyridaine--a general taste enhancer?

  Chemical senses 20030601

• Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation.

  Journal of hematotherapy & stem cell research 20030601

• The Ala45Thr polymorphism of BETA2/NeuroD1 gene and susceptibility to type 2 diabetes mellitus in a Polish population.

  Acta diabetologica 20030601

• Structure-function relationships in 3alpha-hydroxysteroid dehydrogenases: a comparison of the rat and human isoforms.

  The Journal of steroid biochemistry and molecular biology 20030601

• Inhibition of human pepsin and gastricsin by alpha2-macroglobulin.

  Journal of enzyme inhibition and medicinal chemistry 20030601

• Toxicovigilance: new biochemical tool used in sulfonylurea herbicides toxicology studies.

  Acta pharmaceutica (Zagreb, Croatia) 20030601

• Immunohistochemical study on the distribution of alpha-synuclein in the central nervous system of transgenic mice expressing a human Cu/Zn superoxide dismutase mutation.

  Neuroscience letters 20030522

• FEV acts as a transcriptional repressor through its DNA-binding ETS domain and alanine-rich domain.

  Oncogene 20030522

• A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis.

  Journal of the American Chemical Society 20030521

• Hypoxia alters expression and function of syncytin and its receptor during trophoblast cell fusion of human placental BeWo cells: implications for impaired trophoblast syncytialisation in pre-eclampsia.

  Biochimica et biophysica acta 20030520

• [Significance of Factor V gene A506G mutation (Leiden) in the pathogenesis of ischemic stroke].

  Ideggyogyaszati szemle 20030520

• Non-peptide alphavbeta3 antagonists. Part 6: design and synthesis of alphavbeta3 antagonists containing a pyridone or pyrazinone central scaffold.

  Bioorganic & medicinal chemistry letters 20030519

• In search of the energetic role of peptide hydrogen bonds.

  The Journal of biological chemistry 20030516

• Structure-function analysis of T4 RNA ligase 2.

  The Journal of biological chemistry 20030516

• Synthesis of the C(21)-C(26) fragment of superstolide A: concerning the stereochemistry of (E)-crotylboration reactions of alaninal derivatives.

  The Journal of organic chemistry 20030516

• A major step on the road to understanding a unique posttranslational modification and its role in a genetic disease.

  Cell 20030516

• Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C(alpha)-formylglycine generating enzyme.

  Cell 20030516

• Different binding motifs in metabotropic glutamate receptor type 7b for filamin A, protein phosphatase 1C, protein interacting with protein kinase C (PICK) 1 and syntenin allow the formation of multimeric protein complexes.

  The Biochemical journal 20030515

• N[bond]C(alpha) bond dissociation energies and kinetics in amide and peptide radicals. Is the dissociation a non-ergodic process?

  Journal of the American Chemical Society 20030514

• Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.

  Biochemistry 20030513

• Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions.

  Biochemistry 20030513

• Insights into the catalytic mechanism of cofactor-independent phosphoglycerate mutase from X-ray crystallography, simulated dynamics and molecular modeling.

  Journal of molecular biology 20030509

• Identification of a key structural element for protein folding within beta-hairpin turns.

  Journal of molecular biology 20030509

• Involvement of dehydroalanine and dehydrobutyrine in the addition of glutathione to nisin.

  Journal of agricultural and food chemistry 20030507

• Structure and energetics of an allele-specific genetic interaction between dnaJ and dnaK: correlation of nuclear magnetic resonance chemical shift perturbations in the J-domain of Hsp40/DnaJ with binding affinity for the ATPase domain of Hsp70/DnaK.

  Biochemistry 20030506

• Multiple hydrogen kinetic isotope effects for enzymes catalyzing exchange with solvent: application to alanine racemase.

  Biochemistry 20030506

• Synthesis of phosphoryl-tethered beta-cyclodextrins and their molecular and chiral recognition thermodynamics.

  The Journal of organic chemistry 20030502

• Inherent desensitisation-preventing properties of a novel, subtype-selective AMPA receptor agonist, (S)-CPW 399, as a possible explanation for its excitotoxic action in cultured cerebellar granule cells.

  Neurochemistry international 20030501

• Effect of intraportal glucagon-like peptide-1 on glucose metabolism in conscious dogs.

  American journal of physiology. Endocrinology and metabolism 20030501

• Regulation of L-alanine transport systems A and ASC by cyclic AMP and calcium in a reptilian duodenal model.

  The Journal of experimental biology 20030501

• The peroxisome proliferator-activated receptor-gamma2 gene polymorphism (Pro12Ala) beneficially influences insulin resistance and its tracking from childhood to adulthood: the Bogalusa Heart Study.

  Diabetes 20030501

• Adsorption-desorption of metalaxyl as affecting dissipation and leaching in soils: role of mineral and organic components.

  Pest management science 20030501

• Clinical characteristics of the alpha-synuclein mutation (G209A)-associated Parkinson's disease in comparison with other forms of familial Parkinson's disease in Greece.

  European journal of neurology 20030501

• Band-selective recoupling of homonuclear double-quantum dipolar interaction with a generalized composite 0 degrees pulse: application to 13C aliphatic region-selective magnetization transfer in solids.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20030501

• Carbon-13 lineshapes in solid-state NMR of labeled compounds. Effects of coherent CSA-dipolar cross-correlation.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20030501

• Ultrasonic absorption in aqueous solutions of amino acids at neutral pH.

  The Journal of the Acoustical Society of America 20030501

• Contribution of the absolutely conserved B8Gly to the foldability of insulin.

  Biological chemistry 20030501

• Differential effect of the GPIIb/IIIa antagonist orbofiban on human platelet aggregate formation in vitro.

  Thrombosis research 20030501

• Inhibition of transfer messenger RNA aminoacylation and trans-translation by aminoglycoside antibiotics.

  The Journal of biological chemistry 20030425

• Molecular dynamics studies of a molecular switch in the glucocorticoid receptor.

  Journal of molecular biology 20030425

• A structure-based site-directed mutagenesis study on the neurolysin (EC 3.4.24.16) and thimet oligopeptidase (EC 3.4.24.15) catalysis.

  FEBS letters 20030424

• Sensory activity, chemical structure, and synthesis of Maillard generated bitter-tasting 1-oxo-2,3-dihydro-1H-indolizinium-6-olates.

  Journal of agricultural and food chemistry 20030423

• Defining the active site of Schizosaccharomyces pombe C-terminal domain phosphatase Fcp1.

  The Journal of biological chemistry 20030418

• Mapping the paratope of anti-CD4 recombinant Fab 13B8.2 by combining parallel peptide synthesis and site-directed mutagenesis.

  The Journal of biological chemistry 20030418

• Membrane fusion induced by vesicular stomatitis virus depends on histidine protonation.

  The Journal of biological chemistry 20030418

• Matrix assembly induction and cell migration and invasion inhibition by a 13-amino acid fibronectin peptide.

  The Journal of biological chemistry 20030418

• Development of an efficient 'substrate-trapping' mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates.

  The Journal of biological chemistry 20030418

• Identification of a surface charged residue in the S3-S4 linker of the pacemaker (HCN) channel that influences activation gating.

  The Journal of biological chemistry 20030418

• Notch-induced proteolysis and nuclear localization of the Delta ligand.

  The Journal of biological chemistry 20030418

• Using bifunctional polymers presenting vancomycin and fluorescein groups to direct anti-fluorescein antibodies to self-assembled monolayers presenting d-alanine-d-alanine groups.

  Journal of the American Chemical Society 20030416

• Treponema denticola cystalysin exhibits significant alanine racemase activity accompanied by transamination: mechanistic implications.

  The Biochemical journal 20030415

• Definition of structural prerequisites for lipoteichoic acid-inducible cytokine induction by synthetic derivatives.

  Journal of immunology (Baltimore, Md. : 1950) 20030415

• Threonine phosphorylation sites in the beta 2 and beta 7 leukocyte integrin polypeptides.

  Journal of immunology (Baltimore, Md. : 1950) 20030415

• Peptide and nonpeptide antagonist interaction with constitutively active human AT1 receptors.

  Biochemical pharmacology 20030415

• Mechanistic differences in the activation of estrogen receptor-alpha (ER alpha)- and ER beta-dependent gene expression by cAMP signaling pathway(s).

  The Journal of biological chemistry 20030411

• Phosphorylation of serine 1106 in the catalytic domain of topoisomerase II alpha regulates enzymatic activity and drug sensitivity.

  The Journal of biological chemistry 20030411

• Characterization of the inhibition of pyruvate kinase caused by phenylalanine and phenylpyruvate in rat brain cortex.

  Brain research 20030411

• Alanine:glyoxylate aminotransferase peroxisome-to-mitochondrion mistargeting in human hereditary kidney stone disease.

  Biochimica et biophysica acta 20030411

• (S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology.

  Journal of medicinal chemistry 20030410

• Integrin alpha4beta1-dependent adhesion to ADAM 28 (MDC-L) requires an extended surface of the disintegrin domain.

  Biochemistry 20030408

• Characterization of an Escherichia coli mutant MutY with a cysteine to alanine mutation at the iron-sulfur cluster domain.

  Biochemistry 20030408

• Molecular dynamics of 1-palmitoyl-2-oleoylphosphatidylcholine membranes containing transmembrane alpha-helical peptides with alternating leucine and alanine residues.

  Biochemistry 20030408

• A single surface tryptophan in the chitin-binding domain from Bacillus circulans chitinase A1 plays a pivotal role in binding chitin and can be modified to create an elutable affinity tag.

  Biochimica et biophysica acta 20030407

• The heparin/heparan sulfate 2-O-sulfatase from Flavobacterium heparinum. A structural and biochemical study of the enzyme active site and saccharide substrate specificity.

  The Journal of biological chemistry 20030404

• Characterization of an archaeal multidrug transporter with a unique amino acid composition.

  The Journal of biological chemistry 20030404

• Identification of a functionally important conformation-sensitive region of the secretory Na+-K+-2Cl- cotransporter (NKCC1).

  The Journal of biological chemistry 20030404

• Transcriptional activity and DNA binding of heat shock factor-1 involve phosphorylation on threonine 142 by CK2.

  Biochemical and biophysical research communications 20030404

• Visualizing tmRNA entry into a stalled ribosome.

  Science (New York, N.Y.) 20030404

• Enantioselective synthesis of alpha-methyl-D-cysteine and lanthionine building blocks via alpha-methyl-D-serine-beta-lactone.

  Organic letters 20030403

• The energy landscape of unsolvated peptides: the role of context in the stability of alanine/glycine helices.

  Journal of the American Chemical Society 20030402

• Branched-chain amino acid supplementation during bed rest: effect on recovery.

  Journal of applied physiology (Bethesda, Md. : 1985) 20030401

• Blockade of maitotoxin-induced endothelial cell lysis by glycine and L-alanine.

  American journal of physiology. Cell physiology 20030401

• Characterization and phylogenetic analysis of a thermostable N-carbamoyl- l-amino acid amidohydrolase from Bacillus kaustophilus CCRC11223.

  Archives of microbiology 20030401

• Genetic variations of gpx-4 and male infertility in humans.

  Biology of reproduction 20030401

• Adaptation of glucose production and gluconeogenesis to diminishing glucose infusion in preterm infants at varying gestational ages.

  Pediatric research 20030401

• Interaction of glucagon and epinephrine in the control of hepatic glucose production in the conscious dog.

  American journal of physiology. Endocrinology and metabolism 20030401

• Regulatory effects of alanine-group amino acids on serine alkaline protease production by recombinant Bacillus licheniformis.

  Biotechnology and applied biochemistry 20030401

• NEUROD polymorphism Ala45Thr is associated with Type 1 diabetes mellitus in Czech children.

  Diabetes research and clinical practice 20030401

• Polyalanine expansion and frameshift mutations of the paired-like homeobox gene PHOX2B in congenital central hypoventilation syndrome.

  Nature genetics 20030401

• Homotropic versus heterotopic cooperativity of cytochrome P450eryF: a substrate oxidation and spectral titration study.

  Drug metabolism and disposition: the biological fate of chemicals 20030401

• Mutation of the androgen receptor at amino acid 708 (Gly-->Ala) abolishes partial agonist activity of steroidal antiandrogens.

  Molecular pharmacology 20030401

• Structure-activity study of LVV-hemorphin-7: angiotensin AT4 receptor ligand and inhibitor of insulin-regulated aminopeptidase.

  The Journal of pharmacology and experimental therapeutics 20030401

• Tightly winding structure of sequential model peptide for repeated helical region in Samia cynthia ricini silk fibroin studied with solid-state NMR.

  Protein science : a publication of the Protein Society 20030401

• Structure and dynamics of the DNA-binding protein HU of B. stearothermophilus investigated by Raman and ultraviolet-resonance Raman spectroscopy.

  Protein science : a publication of the Protein Society 20030401

• Cardiovascular hypertrophy in diabetic spontaneously hypertensive rats: optimizing blockade of the renin-angiotensin system.

  Clinical science (London, England : 1979) 20030401

• Recombinant peroxiredoxin 5 protects against excitotoxic brain lesions in newborn mice.

  Free radical biology & medicine 20030401

• Glutathione peroxidase 1 genotype is associated with an increased risk of coronary artery disease.

  Coronary artery disease 20030401

• Photoacoustic spectroscopy study of neodymium complexes with alanine, valine, phenylalanine and tryptophan.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030401

• On the contribution of intramolecular H-bonding entropy to the conformational stability of alanine conformations.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030401

• Combinatorial use of sodium laurate with taurine or L-glutamine enhances colonic absorption of rebamipide, poorly absorbable antiulcer drug, without any serious histopathological mucosal damages.

  Journal of pharmaceutical sciences 20030401

• Complexes of vanadium(III) with L-alanine and L-aspartic acid.

  Journal of inorganic biochemistry 20030401

• Fas-mediated apoptosis is dependent on wild-type p53 status in human cancer cells expressing a temperature-sensitive p53 mutant alanine-143.

  Cancer research 20030401

• Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation.

  Journal of neurochemistry 20030401

• Effect of the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor (PPAR) gamma2 gene on the expression of PPARgamma target genes in adipose tissue of massively obese subjects.

  The Journal of clinical endocrinology and metabolism 20030401

• Mutation Ala(171)Thr stabilizes the gonadotropin-releasing hormone receptor in its inactive conformation, causing familial hypogonadotropic hypogonadism.

  The Journal of clinical endocrinology and metabolism 20030401

• Prior peripheral arterial disease and cerebrovascular disease are independent predictors of adverse outcome in patients with acute coronary syndromes: are we doing enough? Results from the Orbofiban in Patients with Unstable Coronary Syndromes-Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study.

  American heart journal 20030401

• Detection of an Ala601Thr mutation of plasminogen gene in 3 out of 36 Korean patients with deep vein thrombosis.

  Journal of Korean medical science 20030401

• Peptido- and glycocalixarenes: playing with hydrogen bonds around hydrophobic cavities.

  Accounts of chemical research 20030401

• Phenotypes of spinocerebellar ataxia type 6 and familial hemiplegic migraine caused by a unique CACNA1A missense mutation in patients from a large family.

  Archives of neurology 20030401

• Content of ileal EAAC1 and hepatic GLT-1 high-affinity glutamate transporters is increased in growing vs. nongrowing lambs, paralleling increased tissue D- and L-glutamate, plasma glutamine, and alanine concentrations.

  Journal of animal science 20030401

• D-alanine piperazine-amides: novel non-imidazole antagonists of the histamine H3 receptor.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030401

• Site-directed mutagenesis of amino acids in the cytoplasmic loop 6/7 of Na,K-ATPase.

  Annals of the New York Academy of Sciences 20030401

• Two-electrode voltage-clamp analysis of Na,K-ATPase asparagine 776 mutants.

  Annals of the New York Academy of Sciences 20030401

• Conserved cholecystokinin receptor transmembrane domain IV amino acids confer peptide affinity.

  Journal of molecular neuroscience : MN 20030401

• Identification of essential amino acids in Humanin, a neuroprotective factor against Alzheimer's disease-relevant insults.

  Peptides 20030401

• [Relationship between Ala98Val variant of hepatocyte nuclear factor-1 alpha gene and late-onset type 2 diabetes in Han nationality].

  Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20030401

• [Synthesis of ternary complexes of rare earth perchlorate with L-alanine and imidazale and the infrared spectral study].

  Guang pu xue yu guang pu fen xi = Guang pu 20030401

• Point mutations in follitropin receptor result in ER retention.

  Molecular and cellular endocrinology 20030328

• Altered alanine plasma levels despite normalized hepatic alanine extraction in the long-term course after liver transplantation.

  Transplantation 20030327

• NMR and parity violation: low-temperature dependence in 1H CRAMPS and 13C CP/MAS ssNMR spectra of alanine enantiomer.

  Biophysical chemistry 20030325

• Mu opioid receptor gene polymorphisms and heroin dependence in Asian populations.

  Neuroreport 20030324

• Selective stabilization of the chorismate mutase transition state by a positively charged hydrogen bond donor.

  Journal of the American Chemical Society 20030319

• Mechanism and energetics of intramolecular hydrogen transfer in amide and peptide radicals and cation-radicals.

  Journal of the American Chemical Society 20030319

• NMR determination of pKa values for Asp, Glu, His, and Lys mutants at each variable contiguous enzyme-inhibitor contact position of the turkey ovomucoid third domain.

  Biochemistry 20030318

• Ornithine decarboxylase promotes catalysis by binding the carboxylate in a buried pocket containing phenylalanine 397.

  Biochemistry 20030318

• A model of repression: CTD analogs and PIE-1 inhibit transcriptional elongation by P-TEFb.

  Genes & development 20030315

• Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition.

  The Journal of biological chemistry 20030314

• Localization of the discontinuous immunodominant region recognized by human anti-thyroperoxidase autoantibodies in autoimmune thyroid diseases.

  The Journal of biological chemistry 20030314

• Proline oxidase induces apoptosis in tumor cells, and its expression is frequently absent or reduced in renal carcinomas.

  The Journal of biological chemistry 20030314

• Amino acid substitutions at position 43 of NaeI endonuclease. Evidence for changes in NaeI structure.

  The Journal of biological chemistry 20030314

• Low density lipoprotein receptor-related protein and factor IXa share structural requirements for binding to the A3 domain of coagulation factor VIII.

  The Journal of biological chemistry 20030314

• Magnetic resonance proton spectroscopy and diffusion weighted imaging of chick embryo brain in ovo.

  Brain research. Developmental brain research 20030314

• Inducible expression of a dominant negative DNA polymerase-gamma depletes mitochondrial DNA and produces a rho0 phenotype.

  The Journal of biological chemistry 20030314

• Motor domain mutation traps kinesin as a microtubule rigor complex.

  Biochemistry 20030311

• Partial rescue of functional interactions of a nonpalmitoylated mutant of the G-protein G alpha s by fusion to the beta-adrenergic receptor.

  Biochemistry 20030311

• Nature of full-length HMGB1 binding to cisplatin-modified DNA.

  Biochemistry 20030311

• Regulation of the RYR1 and RYR2 Ca2+ release channel isoforms by Ca2+-insensitive mutants of calmodulin.

  Biochemistry 20030311

• Engineered fibronectin type III domain with a RGDWXE sequence binds with enhanced affinity and specificity to human alphavbeta3 integrin.

  Journal of molecular biology 20030307

• Low-frequency electromagnetic fields induce a stress effect upon higher plants, as evident by the universal stress signal, alanine.

  Biochemical and biophysical research communications 20030307

• An unprecedented trans-oriented product from the cleavage of a dipeptide.

  Chemical communications (Cambridge, England) 20030307

• A convenient route to the furopyran core of dysiherbaine.

  Organic & biomolecular chemistry 20030307

• Mechanism of flavin mononucleotide cofactor binding to the Desulfovibrio vulgaris flavodoxin. 1. Kinetic evidence for cooperative effects associated with the binding of inorganic phosphate and the 5'-phosphate moiety of the cofactor.

  Biochemistry 20030304

• Mechanism of human S-adenosylmethionine decarboxylase proenzyme processing as revealed by the structure of the S68A mutant.

  Biochemistry 20030304

• Substrate specificity of mutants of the hydroxynitrile lyase from Manihot esculenta.

  Chembiochem : a European journal of chemical biology 20030303

• Glu496Ala polymorphism of human P2X7 receptor does not affect its electrophysiological phenotype.

  American journal of physiology. Cell physiology 20030301

• The effect of the polyproline II (PPII) conformation on the denatured state entropy.

  Protein science : a publication of the Protein Society 20030301

• Transferable atom equivalent multicentered multipole expansion method.

  Journal of computational chemistry 20030301

• Influence of interleukin-12 receptor beta1 polymorphisms on tuberculosis.

  Human genetics 20030301

• Free amino acids in the clam Macoma balthica L. (Bivalvia, Mollusca) from brackish waters of the southern Baltic Sea.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20030301

• Alanine prevents the in vitro inhibition of glycolysis caused by phenylalanine in brain cortex of rats.

  Metabolic brain disease 20030301

• Differential interactions of lamotrigine and related drugs with transmembrane segment IVS6 of voltage-gated sodium channels.

  Neuropharmacology 20030301

• Molecular modeling of interactions of dihydropyridines and phenylalkylamines with the inner pore of the L-type Ca2+ channel.

  Molecular pharmacology 20030301

• Two novel mutations in the COLQ gene cause endplate acetylcholinesterase deficiency.

  Neuromuscular disorders : NMD 20030301

• Progressive skeletal myopathy, a phenotypic variant of desmin myopathy associated with desmin mutations.

  Neuromuscular disorders : NMD 20030301

• Beta-alanine-oxalic acid (1:1) hemihydrate crystal: structure, 13C NMR and vibrational properties, protonation character.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030301

• Analysis of the relationship between the Pro12Ala variant in the PPAR-gamma2 gene and the response rate to therapy with pioglitazone in patients with type 2 diabetes.

  Diabetes care 20030301

• The effect of burn plasma on skeletal muscle proteolysis in rats.

  Burns : journal of the International Society for Burn Injuries 20030301

• The Ala16Val genetic dimorphism modulates the import of human manganese superoxide dismutase into rat liver mitochondria.

  Pharmacogenetics 20030301

• Cytoplasmic surface structures of bacteriorhodopsin modified by site-directed mutations and cation binding as revealed by 13C NMR.

  European biophysics journal : EBJ 20030301

• Enhanced selenium tolerance and accumulation in transgenic Arabidopsis expressing a mouse selenocysteine lyase.

  Plant physiology 20030301

• Selective polarization inversion of protons in rotating solids.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20030301

• Effect of aspartate and asparagine supplementation on fatigue determinants in intense exercise.

  International journal of sport nutrition and exercise metabolism 20030301

• Interaction between vitamin D receptor and vitamin D ligands: two-dimensional alanine scanning mutational analysis.

  Chemistry & biology 20030301

• Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists.

  British journal of pharmacology 20030301

• [Molecular mechanism and physiological roles of trans-translation mediated by tmRNA].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20030301

• Chemical composition of chicken eggshell and shell membranes.

  Poultry science 20030301

• Role of oral blockade of platelet glycoprotein IIb/IIIa on neutrophil activation in patients with acute coronary syndromes.

  Cardiovascular drugs and therapy 20030301

• Chromophore environment provides clue to 'kindling fluorescent protein' riddle.

  The Journal of biological chemistry 20030227

• Novel alpha-melanocyte stimulating hormone peptide analogues with high candidacidal activity.

  Journal of medicinal chemistry 20030227

• Multiresidue pesticide analysis in wines by solid-phase extraction and capillary gas chromatography-mass spectrometric detection with selective ion monitoring.

  Journal of agricultural and food chemistry 20030226

• Structural and kinetic analysis of catalysis by a thiamin diphosphate-dependent enzyme, benzoylformate decarboxylase.

  Biochemistry 20030225

• Dynamic properties of the G93A mutant of copper-zinc superoxide dismutase as detected by NMR spectroscopy: implications for the pathology of familial amyotrophic lateral sclerosis.

  Biochemistry 20030225

• Slow binding of retinal to rhodopsin mutants G90D and T94D.

  Biochemistry 20030225

• Reaction of 1-amino-2-methylenecyclopropane-1-carboxylate with 1-aminocyclopropane-1-carboxylate deaminase: analysis and mechanistic implications.

  Biochemistry 20030225

• Mutational analysis of the complex of human RNase inhibitor and human eosinophil-derived neurotoxin (RNase 2).

  Biochemistry 20030218

• Binding of 2-aryl-4-(piperidin-1-yl)butanamines and 1,3,4-trisubstituted pyrrolidines to human CCR5: a molecular modeling-guided mutagenesis study of the binding pocket.

  Biochemistry 20030218

• Dynamic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: crystallographic studies.

  Biochemistry 20030218

• A hydrophobicity scale for the lipid bilayer barrier domain from peptide permeabilities: nonadditivities in residue contributions.

  Biochemistry 20030218

• Proposed mechanism and functional amino acid residues of malonyl-CoA:anthocyanin 5-O-glucoside-6'''-O-malonyltransferase from flowers of Salvia splendens, a member of the versatile plant acyltransferase family.

  Biochemistry 20030218

• Fructose-1,6-biphosphate prevents excitotoxic neuronal cell death in the neonatal mouse brain.

  Brain research. Developmental brain research 20030216

• A novel hepatitis B virus mutant with A-to-G at nt551 in the surface antigen gene.

  World journal of gastroenterology 20030215

• Comparison of a QM/MM force field and molecular mechanics force fields in simulations of alanine and glycine 'dipeptides' (Ace-Ala-Nme and Ace-Gly-Nme) in water in relation to the problem of modeling the unfolded peptide backbone in solution.

  Proteins 20030215

• Structural changes and facilitated association of tropoelastin.

  Archives of biochemistry and biophysics 20030215

• Negative regulation of the protection of eIF2alpha phosphorylation activity by a unique acidic domain present at the N-terminus of p67.

  Experimental cell research 20030215

• Degradation of racemic and enantiopure metalaxyl in tropical and temperate soils.

  Environmental science & technology 20030215

• Discovery and structure determination of a novel Maillard-derived sweetness enhancer by application of the comparative taste dilution analysis (cTDA).

  Journal of agricultural and food chemistry 20030212

• Dissection of the EntF condensation domain boundary and active site residues in nonribosomal peptide synthesis.

  Biochemistry 20030211

• Association between plasma levels of monocyte chemoattractant protein-1 and long-term clinical outcomes in patients with acute coronary syndromes.

  Circulation 20030211

• Structural analysis of the rate-limiting transition states in the folding of Im7 and Im9: similarities and differences in the folding of homologous proteins.

  Journal of molecular biology 20030207

• Inhibition of amino acid-mTOR signaling by a leucine derivative induces G1 arrest in Jurkat cells.

  Biochemical and biophysical research communications 20030207

• Dual wavelength parametric test of two-state models for circular dichroism spectra of helical polypeptides: anomalous dichroic properties of alanine-rich peptides.

  Journal of the American Chemical Society 20030205

• Mutational analysis of roles for extracellular cysteine residues in the assembly and function of human alpha 7-nicotinic acetylcholine receptors.

  Biochemistry 20030204

• Structural and biochemical studies of inhibitor binding to human cytomegalovirus protease.

  Biochemistry 20030204

• Residues 207, 216, and 221 and the catalytic activity of mGSTA1-1 and mGSTA2-2 toward benzo[a]pyrene-(7R,8S)-diol-(9S,10R)-epoxide.

  Biochemistry 20030204

• Protein and DNA residue orientations in the filamentous virus Pf1 determined by polarized Raman and polarized FTIR spectroscopy.

  Biochemistry 20030204

• Factor VII mutant V154G models a zymogen-like form of factor VIIa.

  The Biochemical journal 20030201

• Substrate-induced conformational transition in human phenylalanine hydroxylase as studied by surface plasmon resonance analyses: the effect of terminal deletions, substrate analogues and phosphorylation.

  The Biochemical journal 20030201

• Aspartate-107 and leucine-109 facilitate efficient coupling of glutamine hydrolysis to CTP synthesis by Escherichia coli CTP synthase.

  The Biochemical journal 20030201

• Affinity and specificity of N-methyl- D-aspartate channel blockers affect their ability to disrupt prepulse inhibition of acoustic startle in rats.

  Psychopharmacology 20030201

• The snakehead Channa asiatica accumulates alanine during aerial exposure, but is incapable of sustaining locomotory activities on land through partial amino acid catabolism.

  The Journal of experimental biology 20030201

• Investigation of the putative immunodominant T cell epitopes in coeliac disease.

  Gut 20030201

• Alanine radicals, part 4: relative amounts of radical species in alanine dosimeters after exposure to 6-19 MeV electrons and 10 kV-15 MV photons.

  Radiation research 20030201

• Systemic and spinal analgesic activity of a delta-opioid-selective lanthionine enkephalin analog.

  The Journal of pharmacology and experimental therapeutics 20030201

• Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy.

  Magnetic resonance in medicine 20030201

• Distribution and characteristics of D-amino acid and D-aspartate oxidases in fish tissues.

  Journal of experimental zoology. Part A, Comparative experimental biology 20030201

• Influence of lansoprazole, famotidine, roxatidine and rebamipide administration on the urea breath test for the diagnosis of Helicobacter pylori infection.

  Journal of gastroenterology and hepatology 20030201

• tmRNA from Thermus thermophilus. Interaction with alanyl-tRNA synthetase and elongation factor Tu.

  European journal of biochemistry 20030201

• Effect of partial substitution of dietary protein by a single gluconeogenic dispensable amino acid on hepatic glucose metabolism in rainbow trout (Oncorhynchus mykiss).

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20030201

• Effects of dual angiotensin-converting enzyme and neutral endopeptidase 24-11 chronic inhibition by mixanpril on insulin sensitivity in lean and obese Zucker rats.

  Journal of cardiovascular pharmacology 20030201

• Nonspecific interaction forces at water-membrane interface by forced molecular dynamics simulations.

  Journal of computational chemistry 20030201

• AMPA receptor potentiation by acetylcholinesterase is age-dependently upregulated at synaptogenesis sites of the rat brain.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20030201

• Use of intein-directed peptide biosynthesis to improve serum stability and bioactivity of a gelatinase inhibitory peptide.

  Combinatorial chemistry & high throughput screening 20030201

• Three hydrates of the bisphosphonate risedronate, consisting of one molecular and two ionic structures.

  Acta crystallographica. Section C, Crystal structure communications 20030201

• Metabolism of brain amino acids following pentylenetetrazole treatment.

  Epilepsy research 20030201

• Mutation of tyrosine 190 to alanine eliminates the inactivation of cytochrome P450 2B1 by peroxynitrite.

  Chemical research in toxicology 20030201

• Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.

  AJNR. American journal of neuroradiology 20030201

• Association of the PRO12ALA polymorphism of the PPAR-gamma2 gene with oxidized low-density lipoprotein and cardiolipin autoantibodies in nondiabetic and type 2 diabetic subjects.

  Metabolism: clinical and experimental 20030201

• Steroid-binding site residues dictate optimal substrate positioning in rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD or AKR1C9).

  Chemico-biological interactions 20030201

• Significance of individual amino acid residues for coenzyme and substrate specificity of 17beta-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus.

  Chemico-biological interactions 20030201

• Determination of distance of intra-molecular hydrogen bonding in (Ala-Gly)15 with silk I form after removal of the effect of MAS frequency in REDOR experiment.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20030201

• Effects of glycine and alanine on short-term storage and cryopreservation of striped bass (Morone saxatilis) spermatozoa.

  Cryobiology 20030201

• 99mTc-alafosfalin: an antibiotic peptide infection imaging agent.

  Nuclear medicine and biology 20030201

• Determination of the torsion angles of alanine and glycine residues of model compounds of spider silk (AGG)(10) using solid-state NMR methods.

  Journal of biomolecular NMR 20030201

• Effect of rebamipide on acetic acid-induced gastric ulcer in rats: involvement of hepatocyte growth factor.

  Scandinavian journal of gastroenterology 20030201

• Characteristics of attenuating effects of rebamipide, an anti-ulcer agent, on oxidative burst of human neutrophils.

  Journal of pharmacological sciences 20030201

• Plasma amino acid levels in children with autism and their families.

  Journal of autism and developmental disorders 20030201

• Determination of the absolute configuration of (+)-xestoaminol C [(2S, 3R)-2-amino-3-tetradecanol], a metabolite of Fiji sponge, Xestospongia sp., by the synthesis of its N,O-diacetyl derivative.

  Bioscience, biotechnology, and biochemistry 20030201

• Synthesis of hydroxymethylglutathione from glutathione and L-serine catalyzed by carboxypeptidase Y.

  Bioscience, biotechnology, and biochemistry 20030201

• Chemoprevention of Helicobacter pylori-associated gastric carcinogenesis in a mouse model: is it possible?

  Journal of biochemistry and molecular biology 20030131

• Large-scale context in protein folding: villin headpiece.

  Biochemistry 20030128

• Analysis of ligand-stimulated CC chemokine receptor 5 (CCR5) phosphorylation in intact cells using phosphosite-specific antibodies.

  The Journal of biological chemistry 20030124

• Posttranslational modification of serine to formylglycine in bacterial sulfatases. Recognition of the modification motif by the iron-sulfur protein AtsB.

  The Journal of biological chemistry 20030124

• Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses.

  Biochemical and biophysical research communications 20030124

• Determination of free L- and D-alanine in hydrolysed protein fertilisers by capillary electrophoresis.

  Journal of chromatography. A 20030124

• Understanding the dynamics of Spinocerebellar Ataxia 8 (SCA8) locus through a comparative genetic approach in humans and apes.

  Neuroscience letters 20030123

• Specific control of peptide assembly with combined hydrophilic and hydrophobic interfaces.

  Journal of the American Chemical Society 20030122

• Biotin sulfoxide reductase: Tryptophan 90 is required for efficient substrate utilization.

  Archives of biochemistry and biophysics 20030115

• Arginine of retinoic acid receptor beta which coordinates with the carboxyl group of retinoic acid functions independent of the amino acid residues responsible for retinoic acid receptor subtype ligand specificity.

  Archives of biochemistry and biophysics 20030115

• Using nitrile-derivatized amino acids as infrared probes of local environment.

  Journal of the American Chemical Society 20030115

• The effect of copper/zinc replacement on the folding free energy of wild type and Cys3Ala/Cys26Ala azurin.

  International journal of biological macromolecules 20030115

• Pentacopper(II) 12-metallacrown-4 complexes with alpha- and beta-aminohydroxamic acids in aqueous solution: a reinvestigation.

  Journal of inorganic biochemistry 20030115

• Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen.

  Biochemistry 20030114

• Dictyostelium myosin II mutations that uncouple the converter swing and ATP hydrolysis cycle.

  Biochemistry 20030114

• Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction.

  Biochemistry 20030114

• Regulation of N- and C-type inactivation of Kv1.4 by pHo and K+: evidence for transmembrane communication.

  American journal of physiology. Heart and circulatory physiology 20030101

• Compartmentation of metabolism probed by [2-13C]alanine: improved 13C NMR sensitivity using a CryoProbe detects evidence of a glial metabolon.

  Neurochemistry international 20030101

• Determination of D-alanine in the rat central nervous system and periphery using column-switching high-performance liquid chromatography.

  Analytical biochemistry 20030101

• Inducible beta-glucosidase synthesis during germination and outgrowth of Bacillus subtilis ATCC 9372 spores.

  Letters in applied microbiology 20030101

• Variability in spore germination response by strains of proteolytic Clostridium botulinum types A, B and F.

  Letters in applied microbiology 20030101

• Molecular basis of partial agonism: orientation of indoleamine ligands in the binding pocket of the human serotonin 5-HT2A receptor determines relative efficacy.

  Molecular pharmacology 20030101

• Alanine radicals, part 3: properties of the components contributing to the EPR spectrum of X-irradiated alanine dosimeters.

  Radiation research 20030101

• Electrostatic interactions in the reconstitution of an SH2 domain from constituent peptide fragments.

  Protein science : a publication of the Protein Society 20030101

• Pressure-induced unfolding of the molten globule of all-Ala alpha-lactalbumin.

  Protein science : a publication of the Protein Society 20030101

• Identification of mouse MD-2 residues important for forming the cell surface TLR4-MD-2 complex recognized by anti-TLR4-MD-2 antibodies, and for conferring LPS and taxol responsiveness on mouse TLR4 by alanine-scanning mutagenesis.

  Journal of immunology (Baltimore, Md. : 1950) 20030101

• Involvement of the system L amino acid transporter on uptake of S-nitroso-L-cysteine, an endogenous S-nitrosothiol, in PC12 cells.

  European journal of pharmacology 20030101

• Identification of formylglycine in sulfatases by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

  Journal of mass spectrometry : JMS 20030101

• Effects of endurance training on the gluconeogenic capacity of periportal and perivenous hepatocytes.

  Physiology & behavior 20030101

• Genetic variation in cyclooxygenase 1: effects on response to aspirin.

  Clinical pharmacology and therapeutics 20030101

• Human CD30: structural implications from epitope mapping and modeling studies.

  Journal of molecular recognition : JMR 20030101

• Clinical utility of grading criteria for submucosal invasion in the prognosis of T1 colorectal carcinomas.

  Journal of gastroenterology 20030101

• Efficacy of rebamipide as adjunctive therapy in the treatment of recurrent oral aphthous ulcers in patients with Behçet's disease: a randomised, double-blind, placebo-controlled study.

  Drugs in R&D 20030101

• [Seasonal differences in activity of tRNA and aminoacyl-tRNA synthetases of rabbit liver in myocardial ischemia].

  Medicina (Kaunas, Lithuania) 20030101

• Breaking non-native hydrophobic clusters is the rate-limiting step in the folding of an alanine-based peptide.

  Biopolymers 20030101

• Lateral gene transfer and ancient paralogy of operons containing redundant copies of tryptophan-pathway genes in Xylella species and in heterocystous cyanobacteria.

  Genome biology 20030101

• [Influence of exercise on serum uric acid].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• Investigation of the mechanisms of therapy-related hypoglycaemia in children with acute lymphoblastic leukaemia.

  Acta paediatrica (Oslo, Norway : 1992) 20030101

• pH-dependent influence of a quaternary ammonium salt and an aminoester on the yeast Saccharomyces cerevisiae ultrastructure.

  Cellular & molecular biology letters 20030101

• [Association study of 5-HT2A receptor gene polymorphism in anorexia nervosa in Polish population].

  Psychiatria polska 20030101

• Altered long-term corticostriatal synaptic plasticity in transgenic mice overexpressing human CU/ZN superoxide dismutase (GLY(93)-->ALA) mutation.

  Neuroscience 20030101

• Synthesis of serine/alanine conjugated 3',5'-TpT.

  Nucleosides, nucleotides & nucleic acids 20030101

• Effectory site in Escherichia coli inorganic pyrophosphatase is revealed upon mutation at the intertrimeric interface.

  IUBMB life 20030101

• Rapid parallel synthesis of dipeptide diphenyl phosphonate esters as inhibitors of dipeptidyl peptidases.

  Journal of combinatorial chemistry 20030101

• Differential roles of alanine in GABAergic and glutamatergic neurons.

  Neurochemistry international 20030101

• Phosphorylation of Xenopus Cdc25C at Ser285 interferes with ability to activate a DNA damage replication checkpoint in pre-midblastula embryos.

  Cell cycle (Georgetown, Tex.) 20030101

• Blocking survivin to kill cancer cells.

  Methods in molecular biology (Clifton, N.J.) 20030101

• A new mutation of 5-alpha-reductase type 2 (A62E) in a large Egyptian kindred.

  Hormone research 20030101

• Enhanced secretion of heterologous cyclodextrin glycosyltransferase by a mutant of Bacillus licheniformis defective in the D-alanylation of teichoic acids.

  Letters in applied microbiology 20030101

• Human dopamine transporter gene variation: effects of protein coding variants V55A and V382A on expression and uptake activities.

  The pharmacogenomics journal 20030101

• [Association of the SOD2 Ala(-9)Val and SOD3 Arg213Gly polymorphisms with diabetic polyneuropathy in patients with diabetes mellitus type 1].

  Molekuliarnaia biologiia 20030101

• Parallel high-throughput accurate mass measurement using a nine-channel multiplexed electrospray liquid chromatography ultraviolet time-of-flight mass spectrometry system.

  Rapid communications in mass spectrometry : RCM 20030101

• [Synthesis and antithrombin activity of phosphoalanine-containing peptides].

  Bioorganicheskaia khimiia 20030101

• Distal hinge of plasminogen activator inhibitor-1 involves its latency transition and specificities toward serine proteases.

  BMC biochemistry 20030101

• Development of homochiral peptides in the chemical evolutionary process: Separation of homochiral and heterochiral oligopeptides.

  Chirality 20030101

• Monoamine oxidase A gene polymorphism, 5-HT 2A receptor gene polymorphism and incidence of nausea induced by fluvoxamine.

  Neuropsychobiology 20030101

• Pressor response to intravenous tyramine in healthy subjects after safinamide, a novel neuroprotectant with selective, reversible monoamine oxidase B inhibition.

  Clinical neuropharmacology 20030101

• Germination of spores of Bacillus subtilis with dodecylamine.

  Journal of applied microbiology 20030101

• Synthesis, degradation kinetics and in vitro antimicrobial activity of tetrahydro-2H-1,3,5-thiadiazine-2-thione derivatives of some beta-amino acids.

  Arzneimittel-Forschung 20030101

• Gas-phase basicity of glycine, alanine, proline, serine, lysine, histidine and some of their peptides by the thermokinetic method.

  European journal of mass spectrometry (Chichester, England) 20030101

• [A rapid and effective solid-phase synthesis of DNA-sequence binding polyamides].

  Bioorganicheskaia khimiia 20030101

• Cryo-bioorganic chemistry: freezing effect on stereoselection of DL-alanine-N-carboxyanhydride oligomerization in dioxane solution.

  Cryo letters 20030101

• In situ brain perfusion technique.

  Methods in molecular medicine 20030101

• Metabolic response of muscle to alanine, glutamine, and valine supplementation during severe illness.

  JPEN. Journal of parenteral and enteral nutrition 20030101

• The 1604A (R496H) mutation in Gaucher disease: genotype/phenotype correlation.

  Blood cells, molecules & diseases 20030101

• Allelic variants of the tryptophan hydroxylase (A218C) and serotonin 1B receptor (A-161T) and personality traits.

  Neuropsychobiology 20030101

• Association of muscarinic m1 receptor genetic polymorphisms with psychiatric symptoms and cognitive function in schizophrenic patients.

  Neuropsychobiology 20030101

• Preoperative administration of rebamipide significantly lowers body temperature and circulating interleukin-6 in gastric cancer patients after gastrectomy.

  Digestive surgery 20030101

• Primary pyruvate dehydrogenase E3 binding protein deficiency with mild hyperlactataemia and hyperalaninaemia.

  Journal of inherited metabolic disease 20030101

• Synthesis and hybridization properties of oligonucleotide analogues containing ornithine backbone modified with nucleoalanines.

  Nucleosides, nucleotides & nucleic acids 20030101

• Substrate specificity and inducibility of TACE (tumour necrosis factor alpha-converting enzyme) revisited: the Ala-Val preference, and induced intrinsic activity.

  Biochemical Society symposium 20030101

• Sugar recognition by human galactokinase.

  BMC biochemistry 20030101

• alpha-Amino-3-hydroxy-5-methyl-isoxazole-4-propionate receptors in spinal cord motor neurons are altered in transgenic mice overexpressing human Cu,Zn superoxide dismutase (Gly93-->Ala) mutation.

  Neuroscience 20030101

• Single dose of glutamine enhances myocardial tissue metabolism, glutathione content, and improves myocardial function after ischemia-reperfusion injury.

  JPEN. Journal of parenteral and enteral nutrition 20030101

• Effect of glutamine dipeptide on hepatic regeneration in partially hepatectomized malnourished rats.

  Nutrition (Burbank, Los Angeles County, Calif.) 20030101

• The structure of tri-proline in water probed by polarized Raman, Fourier transform infrared, vibrational circular dichroism, and electric ultraviolet circular dichroism spectroscopy.

  Biopolymers 20030101

• Enhanced spontaneous activity of the mu opioid receptor by cysteine mutations: characterization of a tool for inverse agonist screening.

  BMC pharmacology 20030101

• The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12.

  Advances in experimental medicine and biology 20030101

• A technique to recover tracer as carboxyl-carbon and alpha-nitrogen from amino acids in soil hydrolysates.

  Journal of AOAC International 20030101

• New tools for the control of peptide conformation and supramolecular chemistry: crown-carrier, C(alpha)-methyl L-DOPA amino acids.

  Biopolymers 20030101

• Interaction of 7-azatryptophan and beta-(1-azulenyl)-alanine with a nitroxyl radical.

  Advances in experimental medicine and biology 20030101

• Histidine 407, a phantom residue in the E1 subunit of the Escherichia coli pyruvate dehydrogenase complex, activates reductive acetylation of lipoamide on the E2 subunit. An explanation for conservation of active sites between the E1 subunit and transketolase.

  Biochemistry 20021231

• Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.

  Biochemistry 20021231

• The catalytic cycle of biosynthetic thiolase: a conformational journey of an acetyl group through four binding modes and two oxyanion holes.

  Biochemistry 20021231

• Mobility of fluorobenzyl alcohols bound to liver alcohol dehydrogenases as determined by NMR and X-ray crystallographic studies.

  Biochemistry 20021231

• Dramatic stabilization of the native state of human carbonic anhydrase II by an engineered disulfide bond.

  Biochemistry 20021231

• In vivo import experiments in protoplasts reveal the importance of the overall context but not specific amino acid residues of the transit peptide during import into chloroplasts.

  Molecules and cells 20021231

• Phage-displayed peptides bind to the malarial protein apical membrane antigen-1 and inhibit the merozoite invasion of host erythrocytes.

  The Journal of biological chemistry 20021227

• Probing the effect of side chains on the conformation and stability of helical peptides via isotope-edited infrared spectroscopy.

  Biochemistry 20021224

• Engineering-specific pharmacological binding sites for peptidyl inhibitors of potassium channels into KcsA.

  Biochemistry 20021224

• Chemical rescue of proton transfer in catalysis by carbonic anhydrases in the beta- and gamma-class.

  Biochemistry 20021224

• Follicle-stimulating hormone interacts with exoloop 3 of the receptor.

  The Journal of biological chemistry 20021220

• Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation.

  The Journal of biological chemistry 20021220

• Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1.

  The Journal of biological chemistry 20021220

• Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes.

  The Journal of biological chemistry 20021220

• The activity of the Arabidopsis bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase enzyme of lysine catabolism is regulated by functional interaction between its two enzyme domains.

  The Journal of biological chemistry 20021220

• The nucleotide-binding site of human sphingosine kinase 1.

  The Journal of biological chemistry 20021220

• The role of intersubunit interactions for the stabilization of the T state of Escherichia coli aspartate transcarbamoylase.

  The Journal of biological chemistry 20021220

• An expanded V2 receptor retention signal.

  FEBS letters 20021218

• The PLP-dependent biotin synthase from Escherichia coli: mechanistic studies.

  FEBS letters 20021218

• Subtype-specific regulation of receptor internalization and recycling by the carboxyl-terminal domains of the human A1 and rat A3 adenosine receptors: consequences for agonist-stimulated translocation of arrestin3.

  Biochemistry 20021217

• Crucial role of conserved lysine 277 in the fidelity of tRNA aminoacylation by Escherichia coli valyl-tRNA synthetase.

  Biochemistry 20021217

• Effects of the phosphodiesterase-IV inhibitor EMD 95832/3 on tumour growth and cachexia in rats bearing the Yoshida AH-130 ascites hepatoma.

  Cancer letters 20021215

• An alanine-zipper structure determined by long range intermolecular interactions.

  The Journal of biological chemistry 20021213

• Valine 114 replacements in archaeal elongation factor 1 alpha enhanced its ability to interact with aminoacyl-tRNA and kirromycin.

  Biochemistry 20021210

• Role of protein and substrate dynamics in catalysis by Pseudomonas putida cytochrome P450cam.

  Biochemistry 20021210

• Ca2+-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor require negative feedback by protein kinase C.

  The Journal of biological chemistry 20021206

• Stabilization of the R allosteric structure of Escherichia coli aspartate transcarbamoylase by disulfide bond formation.

  The Journal of biological chemistry 20021206

• Role of charge properties of bacterial envelope in bactericidal action of human group IIA phospholipase A2 against Staphylococcus aureus.

  The Journal of biological chemistry 20021206

• The position of cysteine relative to the transmembrane domain is critical for palmitoylation of H1, the major subunit of the human asialoglycoprotein receptor.

  The Journal of biological chemistry 20021206

• Characterization of a unique glycosylated anchor endopeptidase that cleaves the LPXTG sequence motif of cell surface proteins of Gram-positive bacteria.

  The Journal of biological chemistry 20021206

• First-principles molecular dynamics investigation of the D-amino acid oxidative half-reaction catalyzed by the flavoenzyme D-amino acid oxidase.

  Biochemistry 20021203

• A heterodimerizing leucine zipper coiled coil system for examining the specificity of a position interactions: amino acids I, V, L, N, A, and K.

  Biochemistry 20021203

• A positively charged amino acid proximal to the C-terminus of TM17 of MRP1 is indispensable for GSH-dependent binding of substrates and for transport of LTC4.

  Biochemistry 20021203

• The human mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiae.

  Biochemistry 20021203

• A short Aib/Ala-based peptide helix is as stable as an Ala-based peptide helix double its length.

  Chembiochem : a European journal of chemical biology 20021202

• Glycosylation of human proteinase-activated receptor-2 (hPAR2): role in cell surface expression and signalling.

  The Biochemical journal 20021201

• A theoretical analysis of the thermodynamic contributions for the adsorption of individual protein residues on functionalized surfaces.

  Biomaterials 20021201

• A monoclonal antibody and an enzyme immunoassay for human Ala-IL-8(77).

  Journal of immunological methods 20021201

• Intracellular pyruvate flux in the methane-producing archaeon Methanococcus maripaludis.

  Archives of microbiology 20021201

• Impact of chronic fructose infusion on hepatic metabolism during TPN administration.

  American journal of physiology. Endocrinology and metabolism 20021201

• The novel antagonist 3-CBW discriminates between kainate receptors expressed on neonatal rat motoneurones and those on dorsal root C-fibres.

  British journal of pharmacology 20021201

• Comparative analysis of various platelet glycoprotein IIb/IIIa antagonists on shear-induced platelet activation and adhesion.

  The Journal of pharmacology and experimental therapeutics 20021201

• Acid hydrolysis of silk fibroins and determination of the enrichment of isotopically labeled amino acids using precolumn derivatization and high-performance liquid chromatography-electrospray ionization-mass spectrometry.

  Analytical biochemistry 20021201

• Valine-alanine manganese superoxide dismutase polymorphism is not associated with alcohol-induced oxidative stress or liver fibrosis.

  Hepatology (Baltimore, Md.) 20021201

• The impact of Glu-->Ala and Glu-->Asp mutations on the crystallization properties of RhoGDI: the structure of RhoGDI at 1.3 A resolution.

  Acta crystallographica. Section D, Biological crystallography 20021201

• The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish population.

  American journal of human genetics 20021201

• A novel androgen receptor mutant, A748T, exhibits hormone concentration-dependent defects in nuclear accumulation and activity despite normal hormone-binding affinity.

  Molecular endocrinology (Baltimore, Md.) 20021201

• Impaired desensitization of a mutant adrenocorticotropin receptor associated with apparent constitutive activity.

  Molecular endocrinology (Baltimore, Md.) 20021201

• Dissociation between muscle tricarboxylic acid cycle pool size and aerobic energy provision during prolonged exercise in humans.

  The Journal of physiology 20021201

• Pirimiphos-methyl and benalaxyl losses in surface runoff from plots cultivated with potatoes.

  Pest management science 20021201

• Clinical phenotype and infertility treatment in a male with hypogonadotropic hypogonadism due to mutations Ala129Asp/Arg262Gln of the gonadotropin-releasing hormone receptor.

  Fertility and sterility 20021201

• Dopamine efflux via wild-type and mutant dopamine transporters: alanine substitution for proline-572 enhances efflux and reduces dependence on extracellular dopamine, sodium and chloride concentrations.

  Brain research. Molecular brain research 20021201

• Solute accumulation in the deep-sea bacterium Photobacterium profundum.

  Extremophiles : life under extreme conditions 20021201

• Platelet glycoprotein IIb/IIIa inhibitors and thrombocytopenia: possible link between platelet activation, autoimmunity and thrombosis.

  Thrombosis and haemostasis 20021201

• Acute thrombocytopenia in patients treated with the oral glycoprotein IIb/IIIa inhibitors xemilofiban and orbofiban: evidence for an immune etiology.

  Thrombosis and haemostasis 20021201

• Transthyretin mutation (TTRGly47Ala) associated with familial amyloid polyneuropathy in a French family.

  Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20021201

• Identification of an indispensable amino acid for ppGpp synthesis of Escherichia coli SpoT protein.

  Bioscience, biotechnology, and biochemistry 20021201

• [BPH pharmacotherapy (miscellaneous)].

  Nihon rinsho. Japanese journal of clinical medicine 20021201

• Effects of membranotropic agents on mono- and multilayer structures of dipalmitoylphosphatidylcholine.

  European biophysics journal : EBJ 20021201

• A screening for superoxide dismutase-1 D90A mutation in Italian patients with sporadic amyotrophic lateral sclerosis.

  Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20021201

• Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase.

  The Journal of biological chemistry 20021129

• Identification of acidic residues in the extracellular loops of the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+ and a positive allosteric modulator.

  The Journal of biological chemistry 20021129

• Synthesis of the L-alanyl-L-alanine cross-bridge of Enterococcus faecalis peptidoglycan.

  The Journal of biological chemistry 20021129

• Molecular discrimination of N-protected amino acid esters by a self-assembled cylindrical capsule: spectroscopic and computational studies.

  The Journal of organic chemistry 20021129

• Dehydroalanine-based inhibition of a peptide epimerase from spider venom.

  The Journal of organic chemistry 20021129

• Mild method for cleavage of dehydroalanine units: highly efficient conversion of nocathiacin I to nocathiacin IV.

  The Journal of organic chemistry 20021129

• D/H amide isotope effect in model alpha-helical peptides.

  Journal of the American Chemical Society 20021127

• Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol.

  The Journal of biological chemistry 20021122

• Interaction of the DnaK and DnaJ chaperone system with a native substrate, P1 RepA.

  The Journal of biological chemistry 20021122

• Limits of cooperativity in a structurally modular protein: response of the Notch ankyrin domain to analogous alanine substitutions in each repeat.

  Journal of molecular biology 20021122

• Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the Metabolic Syndrome.

  Biochimica et biophysica acta 20021120

• An intramolecular disulfide bridge as a catalytic switch for serotonin N-acetyltransferase.

  The Journal of biological chemistry 20021115

• Detailed kinetic analysis and identification of the nucleophile in alpha-L-arabinofuranosidase from Geobacillus stearothermophilus T-6, a family 51 glycoside hydrolase.

  The Journal of biological chemistry 20021115

• Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress.

  The Journal of biological chemistry 20021115

• Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1.

  The Journal of biological chemistry 20021115

• Mutational analysis of baculovirus phosphatase identifies structural residues important for triphosphatase activity in vitro and in vivo.

  Biochemistry 20021112

• Chemical identification of a low abundance lysozyme peptide family bound to I-Ak histocompatibility molecules.

  The Journal of biological chemistry 20021108

• Alanine-scanning mutagenesis of alpha-helix D segment of interleukin-13 reveals new functionally important residues of the cytokine.

  The Journal of biological chemistry 20021108

• Regulation of cAMP-dependent protein kinase activity by glutathionylation.

  The Journal of biological chemistry 20021108

• The catalytic role of the copper ligand H172 of peptidylglycine alpha-hydroxylating monooxygenase (PHM): a spectroscopic study of the H172A mutant.

  Biochemistry 20021105

• Synthesis and biological activity of potent heterocyclic thiol-based inhibitors of endothelin-converting enzyme-1.

  Bioorganic & medicinal chemistry letters 20021104

• A theoretical study of potassium cation binding to glycylglycine (GG) and alanylalanine (AA) dipeptides.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20021104

• A conserved Ala320 in the FtsZ of Porphyromonas gingivalis is important for cell division.

  Current microbiology 20021101

• 13C CP/MAS NMR study on structural heterogeneity in Bombyx mori silk fiber and their generation by stretching.

  Protein science : a publication of the Protein Society 20021101

• Elucidation of the vasoactive intestinal peptide pharmacophore for VPAC(2) receptors in human and rat and comparison to the pharmacophore for VPAC(1) receptors.

  The Journal of pharmacology and experimental therapeutics 20021101

• Alanine metabolism in acute falciparum malaria.

  Tropical medicine & international health : TM & IH 20021101

• PPAR(gamma)2 gene Pro12Ala polymorphism may influence serum level of an adipocyte-derived protein, adiponectin, in the Japanese population.

  Metabolism: clinical and experimental 20021101

• Adult primitive neuroectodermal tumor: proton MR spectroscopic findings with possible application for differential diagnosis.

  Radiology 20021101

• Thin filament regulation and ionic interactions between the N-terminal region in actin and troponin.

  Biophysical journal 20021101

• Amino acid turnover by elongating cattle blastocysts recovered on days 14-16 after insemination.

  Reproduction (Cambridge, England) 20021101

• NisB is required for the dehydration and NisC for the lanthionine formation in the post-translational modification of nisin.

  Microbiology (Reading, England) 20021101

• How the mutation glycine96 to alanine confers glyphosate insensitivity to 5-enolpyruvyl shikimate-3-phosphate synthase from Escherichia coli.

  Planta 20021101

• Sorptive behavior of the phenylamide fungicides, mefenoxam and metalaxyl, and their acid metabolite in typical Cameroonian and German soils.

  Chemosphere 20021101

• The influence of Ala243 (Gly247), Arg215 and Thr226 (Asn230) on the bioluminescence spectra and pH-sensitivity of railroad worm, click beetle and firefly luciferases.

  Photochemistry and photobiology 20021101

• Identification of novel alpha-glucosidase inhibitors by screening libraries based on N- [4-(benzyloxy) benzoyl] alanine derivatives.

  Combinatorial chemistry & high throughput screening 20021101

• Topological studies of the rat brain K+-dependent Na+/Ca2+ exchanger NCKX2.

  Annals of the New York Academy of Sciences 20021101

• Differential responses of an invariant region in the ectodomain of three glycoprotein hormone receptors to mutagenesis and assay conditions.

  Endocrine 20021101

• Regulation of clot retraction by glycoprotein IIb/IIIa antagonists.

  Thrombosis research 20021101

• [Asymmetric photosynthesis of amino acid precursors: implication for origins of biomolecular chirality].

  Uchu Seibutsu Kagaku 20021101

• A flexible route to (5R)-thiolactomycin, a naturally occurring inhibitor of fatty acid synthesis.

  Organic letters 20021031

• Rotational-echo double resonance characterization of the effects of vancomycin on cell wall synthesis in Staphylococcus aureus.

  Biochemistry 20021029

• Synthesis and incorporation of [6,7]-selenatryptophan into dihydrofolate reductase.

  Biochemical and biophysical research communications 20021025

• Molecular dynamics simulation study of the negative correlation in antibody AZ28-catalyzed oxy-cope rearrangement.

  Journal of the American Chemical Society 20021023

• Structural defects within the carbamate tunnel of carbamoyl phosphate synthetase.

  Biochemistry 20021022

• The dual-specific active site of 7,8-diaminopelargonic acid synthase and the effect of the R391A mutation.

  Biochemistry 20021022

• Molecular hinges in protein folding: the urea-denatured state of apomyoglobin.

  Biochemistry 20021022

• In the first extracellular domain of E-cadherin, heterophilic interactions, but not the conserved His-Ala-Val motif, are required for adhesion.

  The Journal of biological chemistry 20021018

• Exocytotic release of alanine from cultured cerebellar neurons.

  Brain research 20021018

• Time-resolved optical Kerr-effect spectroscopy of low-frequency dynamics in Di-L-alanine, poly-L-alanine, and lysozyme in solution.

  Journal of the American Chemical Society 20021016

• Reconstructing NMR spectra of 'invisible' excited protein states using HSQC and HMQC experiments.

  Journal of the American Chemical Society 20021016

• Characterization of the phosphorylation status of the hepatitis B virus X-associated protein 2.

  Archives of biochemistry and biophysics 20021015

• Membrane insertion and dissociation processes of a model transmembrane helix.

  Biochemistry 20021015

• Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor.

  The Journal of biological chemistry 20021011

• The stimulus-secretion coupling of amino acid-induced insulin release. Insulinotropic action of L-alanine.

  Biochimica et biophysica acta 20021010

• Clustered charge-to-alanine mutagenesis of human respiratory syncytial virus L polymerase generates temperature-sensitive viruses.

  Virology 20021010

• Sequence-specific recognition of DNA by hydrophobic, alanine-rich mutants of the basic region/leucine zipper motif investigated by fluorescence anisotropy.

  Biopolymers 20021005

• Autoinhibition and isoform-specific dominant negative inhibition of the type II cGMP-dependent protein kinase.

  The Journal of biological chemistry 20021004

• Absolute asymmetric photoreactions of aliphatic amino acids by circularly polarized synchrotron radiation: critically pH-dependent photobehavior.

  Journal of the American Chemical Society 20021002

• Site-directed mutagenesis reveals a novel catalytic mechanism of Mycobacterium tuberculosis alkylhydroperoxidase C.

  The Biochemical journal 20021001

• A novel mitochondrial DNA tRNA(Ile) (A4267G) mutation in a sporadic patient with mitochondrial myopathy.

  Neuromuscular disorders : NMD 20021001

• Roles of Asp54 and Asp213 in Ca2+ utilization by soluble human CD39/ecto-nucleotidase.

  Archives of biochemistry and biophysics 20021001

• A simple model for polyproline II structure in unfolded states of alanine-based peptides.

  Protein science : a publication of the Protein Society 20021001

• Induction of tumor-reactive CTL by C-side chain variants of the CTL epitope HER-2/neu protooncogene (369-377) selected by molecular modeling of the peptide: HLA-A2 complex.

  Journal of immunology (Baltimore, Md. : 1950) 20021001

• Mechanism of sulfide-quinone reductase investigated using site-directed mutagenesis and sulfur analysis.

  Biochemistry 20021001

• Identification of a family with nonspecific mental retardation (MRX79) with the A140V mutation in the MECP2 gene: is there a need for routine screening?

  Human mutation 20021001

• Insulin sensitively controls the glucagon response to mild hypoglycemia in the dog.

  Diabetes 20021001

• Assessment of enamelysin (MMP-20) selectivity to three peptide bonds on amelogenin sequence.

  Journal of dental research 20021001

• Nuclear export of glucocorticoid receptor is enhanced by c-Jun N-terminal kinase-mediated phosphorylation.

  Molecular endocrinology (Baltimore, Md.) 20021001

• Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase. A site-directed mutagenesis study.

  European journal of biochemistry 20021001

• Influence of proteins Bsp and FemH on cell shape and peptidoglycan composition in group B streptococcus.

  Microbiology (Reading, England) 20021001

• Serine 331 is major site of phosphorylation and desensitization induced by protein kinase C in thromboxane receptor alpha.

  Acta pharmacologica Sinica 20021001

• The MnSOD A16V mitochondrial targeting sequence polymorphism is not associated with increased risk of distal colorectal adenomas: data from a sigmoidoscopy-based case control study.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20021001

• Two second messengers mediate amino acid responses in olfactory sensory neurons of the salamander, Necturus maculosus.

  Chemical senses 20021001

• Taste enhancements between various amino acids and IMP.

  Chemical senses 20021001

• Amino acid content of cell cultures infected with Cowdria ruminantium propagated in a protein-free medium.

  Annals of the New York Academy of Sciences 20021001

• Pigmentary retinopathy in patients with the MELAS mutation 3243A-->G in mitochondrial DNA.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20021001

• Synaptic plasticity in the acoustic startle pathway: the neuronal basis for short-term habituation?

  The European journal of neuroscience 20021001

• Mutation of charged residues in the TR3 death domain does not perturb interaction with TRADD.

  Protein engineering 20021001

• Computing positional isotopomer distributions from tandem mass spectrometric data.

  Metabolic engineering 20021001

• [Research on the synthesis and spectroscopy of the copolymer of polyvinyl alcohol and amino acid].

  Guang pu xue yu guang pu fen xi = Guang pu 20021001

• Balance between two transpeptidation mechanisms determines the expression of beta-lactam resistance in Enterococcus faecium.

  The Journal of biological chemistry 20020927

• Localization of a fibrillar amyloid beta-protein binding domain on its precursor.

  The Journal of biological chemistry 20020927

• Asp1080 upstream of the calmodulin-binding domain is critical for autoinhibition of hPMCA4b.

  The Journal of biological chemistry 20020927

• Orientation and interactions of dipolar molecules during transport through OmpF porin.

  FEBS letters 20020925

• Single amino acid substitution in Bacillus sphaericus phenylalanine dehydrogenase dramatically increases its discrimination between phenylalanine and tyrosine substrates.

  Biochemistry 20020924

• Harmonic mean relationship between affinity for wild-type receptors and alanine-scan mutants.

  Journal of theoretical biology 20020921

• Inhibition of group I metabotropic glutamate receptor responses in vivo in rats by a new generation of carboxyphenylglycine-like amino acid antagonists.

  Neuroscience letters 20020920

• Isolation and characterization of modified species of a mutated (Cys125 -Ala) recombinant human interleukin-2.

  Journal of chromatography. A 20020920

• Influence of the distal his in imparting imidazolate character to the proximal his in heme peroxidase: (1)h NMR spectroscopic study of cyanide-inhibited his42-->ala horseradish peroxidase.

  Journal of the American Chemical Society 20020918

• The initial steps in the hydration of unsolvated peptides: water molecule adsorption on alanine-based helices and globules.

  Journal of the American Chemical Society 20020918

• Site-directed mutagenesis of conserved charged amino acid residues in ClpB from Escherichia coli.

  Biochemistry 20020917

• A 13C-NMR study of the inhibition of papain by a dipeptide-glyoxal inhibitor.

  The Biochemical journal 20020915

• Distinct sites for myotoxic and membrane-damaging activities in the C-terminal region of a Lys49-phospholipase A2.

  The Biochemical journal 20020915

• T cell immunity in connective tissue disease patients targets the RNA binding domain of the U1-70kDa small nuclear ribonucleoprotein.

  Journal of immunology (Baltimore, Md. : 1950) 20020915

• Importance of product inhibition in the kinetics of the acylase hydrolysis reaction by differential stopped flow microcalorimetry.

  Analytical biochemistry 20020915

• Effects of glycoprotein IIb/IIIa antagonists on platelet activation: development of a transfer method to mimic peak to trough receptor occupancy.

  Thrombosis research 20020915

• A comprehensive alanine scanning mutagenesis of the Escherichia coli transcriptional activator SoxS: identifying amino acids important for DNA binding and transcription activation.

  Journal of molecular biology 20020913

• Behavior of metalaxyl and its pure R-enantiomer in sunflower plants (Helianthus annus).

  Journal of agricultural and food chemistry 20020911

• Crystallographic investigation of the role of aspartate 95 in the modulation of the redox potentials of Desulfovibrio vulgaris flavodoxin.

  Biochemistry 20020910

• Enantioselective synthesis and application of the highly fluorescent and environment-sensitive amino acid 6-(2-dimethylaminonaphthoyl) alanine (DANA).

  Chemical communications (Cambridge, England) 20020907

• Genetic analysis of GalR tetramerization in DNA looping during repressosome assembly.

  The Journal of biological chemistry 20020906

• Complex role of the beta 2-beta 3 loop in the interaction of U1A with U1 hairpin II RNA.

  The Journal of biological chemistry 20020906

• Comparison of Cak1p-like cyclin-dependent kinase-activating kinases.

  The Journal of biological chemistry 20020906

• Protein determinants of RNA binding by DNA polymerase of the T4-related bacteriophage RB69.

  The Journal of biological chemistry 20020906

• Electrostatic contributions to site specific DNA cleavage by EcoRV endonuclease.

  Biochemistry 20020903

• Locking the hydrophobic loop 262-274 to G-actin surface by a disulfide bridge prevents filament formation.

  Biochemistry 20020903

• Substituted 3-amino biaryl propionic acids as potent VLA-4 antagonists.

  Bioorganic & medicinal chemistry letters 20020902

• Signal-induced site specific phosphorylation targets Bcl2 to the proteasome pathway.

  International journal of oncology 20020901

• First characterization of a cluster of VanA-type glycopeptide-resistant Enterococcus faecium, Colombia.

  Emerging infectious diseases 20020901

• The type of sodium-coupled solute modulates small bowel mucosal injury, transport function, and ATP after ischemia/reperfusion injury in rats.

  Gastroenterology 20020901

• Geometry and intrinsic tilt of a tryptophan-anchored transmembrane alpha-helix determined by (2)H NMR.

  Biophysical journal 20020901

• Lysine uptake by cloned hCAT-2B: comparison with hCAT-1 and with trophoblast surface membranes.

  The Journal of membrane biology 20020901

• Recognition of core and flanking amino acids of MHC class II-bound peptides by the T cell receptor.

  European journal of immunology 20020901

• The smooth muscle relaxant effect of hydrogen sulphide in vitro: evidence for a physiological role to control intestinal contractility.

  British journal of pharmacology 20020901

• Hepatoprotective effects of 18beta-glycyrrhetinic acid on carbon tetrachloride-induced liver injury: inhibition of cytochrome P450 2E1 expression.

  Pharmacological research 20020901

• Population changes in Phytophthora infestans in Taiwan associated with the appearance of resistance to metalaxyl.

  Pest management science 20020901

• A carbonyl oxygen migration in electrospray ionization mass spectrometry and its application in differentiating alpha- and beta-alanyl peptides.

  Journal of mass spectrometry : JMS 20020901

• Inhibition of the mitochondrial respiratory chain by alanine in rat cerebral cortex.

  Metabolic brain disease 20020901

• Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures.

  Journal of neurochemistry 20020901

• Effect of a new injectable male contraceptive on the seminal plasma amino acids studied by proton NMR spectroscopy.

  Contraception 20020901

• Alanine prevents the reduction of pyruvate kinase activity in brain cortex of rats subjected to chemically induced hyperphenylalaninemia.

  Neurochemical research 20020901

• Equine endurance exercise alters serum branched-chain amino acid and alanine concentrations.

  Equine veterinary journal. Supplement 20020901

• C(alpha) chemical shift tensors in helical peptides by dipolar-modulated chemical shift recoupling NMR.

  Journal of biomolecular NMR 20020901

• CAG mutation effect on rate of progression in Huntington's disease.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20020901

• The thrombin epitope recognizing thrombomodulin is a highly cooperative hot spot in exosite I.

  The Journal of biological chemistry 20020830

• Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway.

  The Journal of biological chemistry 20020830

• Sequence plasticity in the antigen-binding site of a therapeutic anti-HER2 antibody.

  Journal of molecular biology 20020830

• A conserved cis peptide bond is necessary for the activity of Bowman-Birk inhibitor protein.

  Biochemistry 20020827

• A shape-persistent polymeric crystallization template for CaCO3.

  Journal of the American Chemical Society 20020821

• Contribution of aromatic interactions to alpha-helix stability.

  Journal of the American Chemical Society 20020821

• Peptide tic-tac-toe: heterotrimeric coiled-coil specificity from steric matching of multiple hydrophobic side chains.

  Journal of the American Chemical Society 20020821

• Association of human papillomavirus type 58 variant with the risk of cervical cancer.

  Journal of the National Cancer Institute 20020821

• Identification of key amino acid residues in the assembly of enzymes into the pyruvate dehydrogenase complex of Bacillus stearothermophilus: a kinetic and thermodynamic analysis.

  Biochemistry 20020820

• Determination of the ionization state and catalytic function of Glu-133 in peptide deformylase by difference FTIR spectroscopy.

  Biochemistry 20020820

• A study of L-leucine, L-phenylalanine and L-alanine transport in the perfused rat mammary gland: possible involvement of LAT1 and LAT2.

  Biochimica et biophysica acta 20020819

• The anaplerotic substrate alanine stimulates acetate incorporation into glutamate and glutamine in rabbit kidney tubules. A (13)C NMR study.

  The Journal of biological chemistry 20020816

• Monte Carlo simulations of the peptide recognition at the consensus binding site of the constant fragment of human immunoglobulin G: the energy landscape analysis of a hot spot at the intermolecular interface.

  Proteins 20020815

• Purinergic regulation of glucose and glutamine synthesis in isolated rabbit kidney-cortex tubules.

  Archives of biochemistry and biophysics 20020815

• Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease.

  Blood 20020815

• Synthesis and biological activities of cyclic lanthionine enkephalin analogues: delta-opioid receptor selective ligands.

  Journal of medicinal chemistry 20020815

• Characterization of overoxidized polypyrrole colloids imprinted with L-lactate and their application to enantioseparation of amino acids.

  Analytical chemistry 20020815

• A conserved Tyr residue is required for sugar selectivity in a Pol alpha DNA polymerase.

  Biochemistry 20020813

• Redox-dependent structural changes in the superoxide reductase from Desulfoarculus baarsii and Treponema pallidum: a FTIR study.

  Biochemistry 20020813

• Protein engineering of protein kinase A catalytic subunits results in the acquisition of novel inhibitor sensitivity.

  The Journal of biological chemistry 20020809

• Ultraviolet-B activates components of the systemin signaling pathway in Lycopersicon peruvianum suspension-cultured cells.

  The Journal of biological chemistry 20020809

• Molecular characterization of an extended binding site for coagulation factor Va in the positive exosite of activated protein C.

  The Journal of biological chemistry 20020809

• Glucocorticoid receptor domain requirements for chromatin remodeling and transcriptional activation of the mouse mammary tumor virus promoter in different nucleoprotein contexts.

  The Journal of biological chemistry 20020802

• The conformation of dehydroalanine in short homopeptides: molecular dynamics simulations of a 6-residue chain.

  Biophysical chemistry 20020802

• A buried polar residue in the hydrophobic interface of the coiled-coil peptide, GCN4-p1, plays a thermodynamic, not a kinetic role in folding.

  Journal of molecular biology 20020802

• Site-directed mutagenesis of Tyr354 in Geobacillus stearothermophilus alanine racemase identifies a role in controlling substrate specificity and a possible role in the evolution of antibiotic resistance.

  Chembiochem : a European journal of chemical biology 20020802

• Microbiological transformation of L-tyrosine to 3,4-dihydroxyphenyl L-alanine (L-dopa) by a mutant strain of Aspergillus oryzae UV-7.

  Current microbiology 20020801

• A massive increase in serum beta-glucuronidase after a single dose of carbon tetrachloride to the rat.

  Clinica chimica acta; international journal of clinical chemistry 20020801

• Re-engineering butyrylcholinesterase as a cocaine hydrolase.

  Molecular pharmacology 20020801

• Differential metabolic fate of the carbon skeleton and amino-N of [13C]alanine and [15N]alanine ingested during prolonged exercise.

  Journal of applied physiology (Bethesda, Md. : 1985) 20020801

• Inhibition of Na(+)-dependent transporters in cystine-loaded human renal cells: electrophysiological studies on the Fanconi syndrome of cystinosis.

  Journal of the American Society of Nephrology : JASN 20020801

• Selective alpha4beta7 integrin antagonists and their potential as antiinflammatory agents.

  Journal of medicinal chemistry 20020801

• Characterization of a novel phenazine antibiotic gene cluster in Erwinia herbicola Eh1087.

  Molecular microbiology 20020801

• Analysis of the variations of follicular fluid composition during follicular growth and maturation in the mare using proton nuclear magnetic resonance (1H NMR).

  Reproduction (Cambridge, England) 20020801

• Antecedent treatment with different antibiotic agents as a risk factor for vancomycin-resistant Enterococcus.

  Emerging infectious diseases 20020801

• Osmolyte effects on helix formation in peptides and the stability of coiled-coils.

  Protein science : a publication of the Protein Society 20020801

• The peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism.

  Diabetes 20020801

• Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study.

  Diabetes 20020801

• Peroxisome proliferator-activated receptor-gamma2 polymorphism Pro12Ala is associated with nephropathy in type 2 diabetes: The Berlin Diabetes Mellitus (BeDiaM) Study.

  Diabetes 20020801

• The role of amino-acid residues Q39 and E451 in the determination of substrate specificity of the Spodoptera frugiperda beta-glycosidase.

  European journal of biochemistry 20020801

• Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination.

  Genes & development 20020801

• N-(L-2-Aminobutyryl)-L-alanine and 2-(L-alanylamino)-L-butyric acid 0.33-hydrate.

  Acta crystallographica. Section C, Crystal structure communications 20020801

• Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: homozygosity of the Ala allele confers a decreased risk of the insulin resistance syndrome.

  The Journal of clinical endocrinology and metabolism 20020801

• Optimisation of the expression of a Trametes versicolor laccase gene in Pichia pastoris.

  Journal of industrial microbiology & biotechnology 20020801

• Cerebrospinal fluid glutamine, tryptophan, and tryptophan metabolite concentrations in dogs with portosystemic shunts.

  American journal of veterinary research 20020801

• Changes in expression and function of syncytin and its receptor, amino acid transport system B(0) (ASCT2), in human placental choriocarcinoma BeWo cells during syncytialization.

  Placenta 20020801

• [Evaluation of liver function with 13C-labelled amino acid using hepatectomized rat model].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20020801

• Impaired system A amino acid transport mimics the catabolic effects of acid in L6 cells.

  European journal of clinical investigation 20020801

• Interaction of Cu(+) and Cu(2+) ions with alpha-alanine. A density functional study.

  Journal of mass spectrometry : JMS 20020801

• L-alanine supplementation in late infantile glycogen storage disease type II.

  Pediatric neurology 20020801

• Effects of epidermal growth factor on placental amino acids uptake in pregnant rats.

  The Journal of veterinary medical science 20020801

• Double-quantum dipolar recoupling at high magic-angle spinning rates.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20020801

• [Association of the renin-angiotensin system gene polymorphism with nephropathy in type II diabetes].

  Polskie Archiwum Medycyny Wewnetrznej 20020801

• Modulating acetyl-CoA binding in the GCN5 family of histone acetyltransferases.

  The Journal of biological chemistry 20020726

• Orientational constraints of the gp130 intracellular juxtamembrane domain for signaling.

  The Journal of biological chemistry 20020726

• Characterization of the first cytoplasmic loop of subunit a of the Escherichia coli ATP synthase by surface labeling, cross-linking, and mutagenesis.

  The Journal of biological chemistry 20020726

• Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation.

  Journal of molecular biology 20020726

• Ras signaling enhances the activity of C/EBP alpha to induce granulocytic differentiation by phosphorylation of serine 248.

  The Journal of biological chemistry 20020719

• Acidic residues in the lactococcal multidrug efflux pump LmrP play critical roles in transport of lipophilic cationic compounds.

  The Journal of biological chemistry 20020719

• Identification of two C-terminal amino acids, Ser(355) and Thr(357), required for short-term homologous desensitization of mu-opioid receptors.

  Biochemical pharmacology 20020715

• Staphylococcus aureus strains lacking D-alanine modifications of teichoic acids are highly susceptible to human neutrophil killing and are virulence attenuated in mice.

  The Journal of infectious diseases 20020715

• Identification of functionally important residues of the epidermal growth factor-2 domain of factor IX by alanine-scanning mutagenesis. Residues Asn(89)-Gly(93) are critical for binding factor VIIIa.

  The Journal of biological chemistry 20020712

• Structural determinants for the action of grayanotoxin in D1 S4-S5 and D4 S4-S5 intracellular linkers of sodium channel alpha-subunits.

  Biochemical and biophysical research communications 20020712

• Induction of neuronal differentiation by a peptide corresponding to the homophilic binding site of the second Ig module of the neural cell adhesion molecule.

  The Journal of biological chemistry 20020705

• Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis.

  Journal of molecular biology 20020705

• Enantioselective guest exchange in a chiral resorcin[4]arene cavity.

  Journal of the American Chemical Society 20020703

• Inhibition of ubiquitin-dependent proteolysis by a synthetic glycine-alanine repeat peptide that mimics an inhibitory viral sequence.

  FEBS letters 20020703

• Mutational analysis of endonuclease V from Thermotoga maritima.

  Biochemistry 20020702

• Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation.

  Journal of immunology (Baltimore, Md. : 1950) 20020701

• Hepatic gluconeogenic capacity from various precursors in young versus old rats.

  Metabolism: clinical and experimental 20020701

• Organization of model helical peptides in lipid bilayers: insight into the behavior of single-span protein transmembrane domains.

  Biophysical journal 20020701

• Illuminating proteins with Aladan's lamp.

  Nature structural biology 20020701

• The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth.

  Diabetes 20020701

• Germination of Bacillus cereus spores in response to L-alanine and to inosine: the roles of gerL and gerQ operons.

  Microbiology (Reading, England) 20020701

• ELF magnetic fields increase amino acid uptake into Vicia faba L. roots and alter ion movement across the plasma membrane.

  Bioelectromagnetics 20020701

• Structural and thermodynamic characterization of the DNA binding properties of a triple alanine mutant of MATalpha2.

  Structure (London, England : 1993) 20020701

• Chronological change of brain abscess in (1)H magnetic resonance spectroscopy.

  Neuroradiology 20020701

• Rebamipide prevents delay of acetic acid-induced gastric ulcer healing caused by Helicobacter pylori infection in Mongolian gerbils.

  Digestive diseases and sciences 20020701

• Synthesis of a 2-arylsulphonylated tryptophan: the antibacterial activity of bovine lactoferricin peptides containing Trp(2-Pmc).

  Journal of peptide science : an official publication of the European Peptide Society 20020701

• Involvement of cytochrome P450 in the metabolism of rebamipide by the human liver.

  Xenobiotica; the fate of foreign compounds in biological systems 20020701

• Effectiveness of municipal waste compost and its humic fraction in suppressing Pythium ultimum.

  Microbial ecology 20020701

• Synthesis of methylenecyclobutane analogues of nucleosides with axial chirality and their phosphoralaninates: a new pronucleotide effective against Epstein-Barr virus.

  Antiviral chemistry & chemotherapy 20020701

• Differential interactions of estrogens and antiestrogens at the 17 beta-hydroxyl or counterpart hydroxyl with histidine 524 of the human estrogen receptor alpha.

  Biochemistry 20020625

• Key motif to gain selectivity at the neuropeptide Y5-receptor: structure and dynamics of micelle-bound [Ala31, Pro32]-NPY.

  Biochemistry 20020625

• Ala31-Aib32: identification of the key motif for high affinity and selectivity of neuropeptide Y at the Y5-receptor.

  Biochemistry 20020625

• Scanning mutagenesis of a Janus-faced atracotoxin reveals a bipartite surface patch that is essential for neurotoxic function.

  The Journal of biological chemistry 20020621

• Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase.

  The Journal of biological chemistry 20020621

• The Golgi localization of phosphatidylinositol transfer protein beta requires the protein kinase C-dependent phosphorylation of serine 262 and is essential for maintaining plasma membrane sphingomyelin levels.

  The Journal of biological chemistry 20020621

• Unique activation mechanism of protein kinase CK2. The N-terminal segment is essential for constitutive activity of the catalytic subunit but not of the holoenzyme.

  The Journal of biological chemistry 20020621

• Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters.

  The Journal of biological chemistry 20020621

• RACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death.

  The Journal of biological chemistry 20020621

• A novel alanine-insensitive D-serine transporter in rat brain synaptosomal membranes.

  Brain research 20020621

• Nonnatural amino acid ligands in heme protein design.

  Journal of the American Chemical Society 20020619

• Residue-specific real-time NMR diffusion experiments define the association states of proteins during folding.

  Journal of the American Chemical Society 20020619

• Use of an in situ disulfide cross-linking strategy to map proximities between amino acid residues in transmembrane domains I and VII of the M3 muscarinic acetylcholine receptor.

  Biochemistry 20020618

• Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation.

  Biochemistry 20020618

• Identification of a new class of inhibitors of the voltage-gated potassium channel, Kv1.3, with immunosuppressant properties.

  Biochemistry 20020618

• Degradation of contrasting pesticides by white rot fungi and its relationship with ligninolytic potential.

  FEMS microbiology letters 20020618

• Citrulline and DRIP-1 protein (ArgE homologue) in drought tolerance of wild watermelon.

  Annals of botany 20020615

• HOXD13 polyalanine tract expansion in classical synpolydactyly type Vordingborg.

  American journal of medical genetics 20020615

• Effect of pore structure on surface characteristics of zirconium phosphate-modified silica.

  Journal of colloid and interface science 20020615

• Thermodynamic quantities of surface formation of aqueous electrolyte solutions. V. Aqueous solutions of aliphatic amino acids.

  Journal of colloid and interface science 20020615

• Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice results in IGFBP-4 stabilization and smooth muscle hypotrophy.

  The Journal of biological chemistry 20020614

• Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion.

  Biochemistry 20020611

• The synergistic anion-binding sites of human transferrin: chemical and physiological effects of site-directed mutagenesis.

  Biochemistry 20020611

• Disruption of the alpha5 helix of transducin impairs rhodopsin-catalyzed nucleotide exchange.

  Biochemistry 20020604

• Functional role of the prokaryotic proline-tRNA synthetase insertion domain in amino acid editing.

  Biochemistry 20020604

• Betaine is a highly effective organic osmolyte but does not appear to be transported by established organic osmolyte transporters in mouse embryos.

  Molecular reproduction and development 20020601

• Troglitazone induces a cellular acidosis by inhibiting acid extrusion in cultured rat mesangial cells.

  American journal of physiology. Regulatory, integrative and comparative physiology 20020601

• Molecular basis of the selectivity of gastrin-releasing peptide receptor for gastrin-releasing peptide.

  Molecular pharmacology 20020601

• Atypical muscle pathology and a survey of cis-mutations in deaf patients harboring a 1555 A-to-G point mutation in the mitochondrial ribosomal RNA gene.

  Neuromuscular disorders : NMD 20020601

• Amino acid kinetics during the anhepatic phase of liver transplantation.

  Diabetes 20020601

• A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secretion.

  Diabetes 20020601

• Mitochondrial targeting of the human peptide methionine sulfoxide reductase (MSRA), an enzyme involved in the repair of oxidized proteins.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020601

• Diagnosis and treatment of maple syrup disease: a study of 36 patients.

  Pediatrics 20020601

• Glutamine concentration and tissue exchange with intravenously administered alpha-ketoglutaric acid and ammonium: a dose-response study in the pig.

  Nutrition (Burbank, Los Angeles County, Calif.) 20020601

• [Association of Pro12Ala variant in peroxisome proliferator-activated receptor-gamma2 gene with type 2 diabetes mellitus].

  Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20020601

• Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation.

  Genes & development 20020601

• Phosphorylation of the mitotic regulator Pds1/securin by Cdc28 is required for efficient nuclear localization of Esp1/separase.

  Genes & development 20020601

• Lack of association between calcium-sensing receptor gene 'A986S' polymorphism and bone mineral density in Hungarian postmenopausal women.

  Bone 20020601

• Creatinine inhibits D-amino acid oxidase.

  Nephron 20020601

• Reassessment of major products of N2 fixation by bacteroids from soybean root nodules.

  Microbiology (Reading, England) 20020601

• Modulatory effects of plasma and colonic milieu of patients with ulcerative colitis on neutrophil reactive oxygen species production in presence of a novel antioxidant, rebamipide.

  Digestive diseases and sciences 20020601

• Local gastric and serum concentrations of rebamipide following oral ingestion in healthy volunteers.

  Digestive diseases and sciences 20020601

• A molecular genetic dissection of the evolutionarily conserved N terminus of yeast Rad52.

  Genetics 20020601

• Is a Pro12Ala polymorphism of the PPARgamma2 gene related to obesity and type 2 diabetes mellitus in the Czech population?

  Annals of the New York Academy of Sciences 20020601

• Gamma irradiation effects and EPR investigation on poly(lactide-co-glycolide) microspheres containing bupivacaine.

  Farmaco (Societa chimica italiana : 1989) 20020601

• Uncertainties in alanine dosimetry in the therapeutic dose range.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20020601

• Electrolyte and additive effects on enantiomer separation of peptides by nonaqueous ion-pair capillary electrophoresis using tert.-butylcarbamoylquinine as chiral counterion.

  Electrophoresis 20020601

• Structure-activity relationship and signal transduction of gamma-MSH peptides in GH3 cells: further evidence for a new melanocortin receptor.

  Peptides 20020601

• Transient pseudo-isotachophoresis for sample concentration in capillary electrophoresis.

  Electrophoresis 20020601

• Strategies for access to enantiomerically pure ecadotril, dexecadotril and fasidotril: a review.

  Mini reviews in medicinal chemistry 20020601

• Phosphorylation-dependent cellular localization and thermoprotective role of heat shock protein 25 in hippocampal progenitor cells.

  The Journal of biological chemistry 20020531

• Probing protein electrostatics with a synthetic fluorescent amino acid.

  Science (New York, N.Y.) 20020531

• [Effects of different enteral nutrients on gut absorptive capacity and energy metabolism during gut ischemia/reperfusion].

  Zhonghua yi xue za zhi 20020525

• Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine.

  The Journal of biological chemistry 20020524

• On the role of the conformational flexibility of the active-site lid on the allosteric kinetics of glucosamine-6-phosphate deaminase.

  Journal of molecular biology 20020524

• Hsc62, Hsc56, and GrpE, the third Hsp70 chaperone system of Escherichia coli.

  Biochemical and biophysical research communications 20020524

• Optimizing an artificial metabolic pathway: engineering the cofactor specificity of Corynebacterium 2,5-diketo-D-gluconic acid reductase for use in vitamin C biosynthesis.

  Biochemistry 20020521

• Mutagenesis and mechanism-based inhibition of Streptococcus pyogenes Glu-tRNAGln amidotransferase implicate a serine-based glutaminase site.

  Biochemistry 20020521

• R150A mutant of F TraI relaxase domain: reduced affinity and specificity for single-stranded DNA and altered fluorescence anisotropy of a bound labeled oligonucleotide.

  Biochemistry 20020521

• The A167Y mutation converts the herpes simplex virus type 1 thymidine kinase into a guanosine analogue kinase.

  Biochemistry 20020521

• Folding and conformational consequences of glycine to alanine replacements at different positions in a collagen model peptide.

  Biochemistry 20020521

• Substitution of Met-69 by Ala or Gly in TEM-1 beta-lactamase confer an increased susceptibility to clavulanic acid and other inhibitors.

  FEMS microbiology letters 20020521

• Exploring the stereochemistry of CXCR4-peptide recognition and inhibiting HIV-1 entry with D-peptides derived from chemokines.

  The Journal of biological chemistry 20020517

• Crystal structure of the human estrogen sulfotransferase-PAPS complex: evidence for catalytic role of Ser137 in the sulfuryl transfer reaction.

  The Journal of biological chemistry 20020517

• Total synthesis of dysiherbaine.

  The Journal of organic chemistry 20020517

• The motilin pharmacophore in CHO cells expressing the human motilin receptor.

  Biochemical and biophysical research communications 20020517

• Differential activation of individual subunits in heteromeric kainate receptors.

  Neuron 20020516

• Discrimination between peptide 3(10)- and alpha-helices. Theoretical analysis of the impact of alpha-methyl substitution on experimental spectra.

  Journal of the American Chemical Society 20020515

• Functional and structural changes due to a serine to alanine mutation in the active-site flap of enolase.

  Archives of biochemistry and biophysics 20020515

• Partially folded structure of flavin adenine dinucleotide-depleted ferredoxin-NADP+ reductase with residual NADP+ binding domain.

  The Journal of biological chemistry 20020510

• Novel mode of action of angiotensin I converting enzyme inhibitors: direct activation of bradykinin B1 receptor.

  The Journal of biological chemistry 20020510

• Effects of thioamide substitutions on the conformation and stability of alpha- and 3(10)-helices.

  Journal of the American Chemical Society 20020508

• L-AP3 blocks rises in intracellular calcium associated with hippocampal CA1 LTP.

  Neuroreport 20020507

• Chlorella virus RNA triphosphatase. Mutational analysis and mechanism of inhibition by tripolyphosphate.

  The Journal of biological chemistry 20020503

• ADAMTS4 cleaves at the aggrecanase site (Glu373-Ala374) and secondarily at the matrix metalloproteinase site (Asn341-Phe342) in the aggrecan interglobular domain.

  The Journal of biological chemistry 20020503

• A novel allelic variant of the human TSG-6 gene encoding an amino acid difference in the CUB module. Chromosomal localization, frequency analysis, modeling, and expression.

  The Journal of biological chemistry 20020503

• Core side-chain packing and backbone conformation in Lpp-56 coiled-coil mutants.

  Journal of molecular biology 20020503

• Certification of the critical importance of L-3-(2-naphthyl)alanine at position 3 of a specific CXCR4 inhibitor, T140, leads to an exploratory performance of its downsizing study.

  Bioorganic & medicinal chemistry 20020501

• Structural determinants and specificities for ROMK1-phosphoinositide interaction.

  American journal of physiology. Renal physiology 20020501

• Computational studies on prion proteins: effect of Ala(117)-->Val mutation.

  Biophysical journal 20020501

• Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure.

  Blood 20020501

• Synthesis and biological evaluation on hMC3, hMC4 and hMC5 receptors of gamma-MSH analogs substituted with L-alanine.

  The journal of peptide research : official journal of the American Peptide Society 20020501

• Posttranslational alanine trans-stimulation of zwitterionic amino acid transport systems in human intestinal Caco-2 cells.

  The Journal of surgical research 20020501

• Prevention of overt hypoglycemia during exercise: stimulation of endogenous glucose production independent of hepatic catecholamine action and changes in pancreatic hormone concentration.

  Diabetes 20020501

• Characterization of the retinoid orphan-related receptor-alpha coactivator binding interface: a structural basis for ligand-independent transcription.

  Molecular endocrinology (Baltimore, Md.) 20020501

• Exercise with low muscle glycogen augments TCA cycle anaplerosis but impairs oxidative energy provision in humans.

  The Journal of physiology 20020501

• ClpP-dependent degradation of PopR allows tightly regulated expression of the clpP3 clpP4 operon in Streptomyces lividans.

  Molecular microbiology 20020501

• Expression, mutagenesis and kinetic analysis of recombinant K1E endosialidase to define the site of proteolytic processing and requirements for catalysis.

  Molecular microbiology 20020501

• The role of spinal neurokinin-1 and glutamate receptors in hyperalgesia and allodynia induced by prostaglandin E(2) or zymosan in the rat.

  Pain 20020501

• Homonuclear zero-quantum recoupling in fast magic-angle spinning nuclear magnetic resonance.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20020501

• Hb G Makassar (beta 6:Glu-Ala) in a Thai family.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20020501

• Structure of Ala24/Asp61 --> Asp24/Asn61 substituted subunit c of Escherichia coli ATP synthase: implications for the mechanism of proton transport and rotary movement in the F0 complex.

  Biochemistry 20020430

• Phosphorylation-dependent interaction of kinesin light chain 2 and the 14-3-3 protein.

  Biochemistry 20020430

• Protein engineering and properties of human metalloproteinase and thrombospondin 1.

  Biochemical and biophysical research communications 20020426

• Hydrophobic residue contributions to sequence-specific DNA binding by the bovine papillomavirus helicase E1.

  Virology 20020425

• The energy landscape of unsolvated peptides: helix formation and cold denaturation in Ac-A4G7A4 + H+.

  Journal of the American Chemical Society 20020424

• Primary sequence determinants responsible for site-selective dephosphorylation of the PDGF beta-receptor by the receptor-like protein tyrosine phosphatase DEP-1.

  FEBS letters 20020424

• Role of T7 RNA polymerase His784 in start site selection and initial transcription.

  Biochemistry 20020423

• Analysis of engineered fibrinogen variants suggests that an additional site mediates platelet aggregation and that 'B-b' interactions have a role in protofibril formation.

  Biochemistry 20020423

• Radiation dose measurements with alanine/agarose gel and thin alanine films around a 192Ir brachytherapy source, using ESR spectroscopy.

  Physics in medicine and biology 20020421

• Preliminary evaluation of second harmonic direct detection scheme for low-dose range in alanine/EPR dosimetry.

  Physics in medicine and biology 20020421

• The streptococcal hyaluronan synthases are inhibited by sulfhydryl-modifying reagents, but conserved cysteine residues are not essential for enzyme function.

  The Journal of biological chemistry 20020419

• Ru(II)-catalyzed cascade reactions in stereocontrolled construction of rigid as-indacene-bridged bis(alpha-amino acid) derivatives.

  The Journal of organic chemistry 20020419

• A novel short peptide is a specific inhibitor of the human immunodeficiency virus type 1 integrase.

  Journal of molecular biology 20020419

• Biomimetic stereoselective formation of methyllanthionine.

  Organic letters 20020418

• Ligand-independent oncogenic transformation by the EGF receptor requires kinase domain catalytic activity.

  Experimental cell research 20020415

• Effect of three n-acetylamino acids on N-(3,5-dichlorophenyl)succinimide (NDPS) and ndps metabolite nephrotoxicity in Fischer 344 rats.

  Journal of toxicology and environmental health. Part A 20020412

• Characterisation and cloning of a Na(+)-dependent broad-specificity neutral amino acid transporter from NBL-1 cells: a novel member of the ASC/B(0) transporter family.

  Biochimica et biophysica acta 20020412

• The role of configurational entropy in biochemical cooperativity.

  Journal of the American Chemical Society 20020410

• Probing the role of the F-helix in serpin stability through a single tryptophan substitution.

  Biochemistry 20020409

• Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy.

  The Journal of biological chemistry 20020405

• Essential hydrophilic carboxyl-terminal regions including cysteine residues of the yeast stretch-activated calcium-permeable channel Mid1.

  The Journal of biological chemistry 20020405

• Mapping the epitope of an inhibitory monoclonal antibody to the C-terminal DNA-binding domain of HIV-1 integrase.

  The Journal of biological chemistry 20020405

• Regulation of protein kinase C in Escherichia coli K1 invasion of human brain microvascular endothelial cells.

  The Journal of biological chemistry 20020405

• Functional interaction of MutY homolog with proliferating cell nuclear antigen in fission yeast, Schizosaccharomyces pombe.

  The Journal of biological chemistry 20020405

• Solution NMR study of the monomeric form of p13suc1 protein sheds light on the hinge region determining the affinity for a phosphorylated substrate.

  The Journal of biological chemistry 20020405

• The Clostridium ramosum IgA proteinase represents a novel type of metalloendopeptidase.

  The Journal of biological chemistry 20020405

• The simultaneous biosynthesis and uptake of amino acids by Lactococcus lactis studied by (13)C-labeling experiments.

  Biotechnology and bioengineering 20020405

• Effect of multivalency on the performance of enantioselective separation media for chiral HPLC prepared by linking multiple selectors to a porous polymer support via aliphatic dendrons.

  The Journal of organic chemistry 20020405

• Chiral tricyclic iminolactone derived from (1R)-(+)-camphor as a glycine equivalent for the asymmetric synthesis of alpha-amino acids.

  The Journal of organic chemistry 20020405

• Exploring the role of alanine in the structure of the Lac repressor tetramerization domain, a ferritin-like Alacoil.

  Journal of molecular biology 20020405

• Zn(2+) binding properties of single-point mutants of the C-terminal zinc finger of the HIV-1 nucleocapsid protein: evidence of a critical role of cysteine 49 in Zn(2+) dissociation.

  Biochemistry 20020402

• Mechanistic analyses of catalysis in human pancreatic alpha-amylase: detailed kinetic and structural studies of mutants of three conserved carboxylic acids.

  Biochemistry 20020402

• A critical analysis of continuum electrostatics: the screened Coulomb potential--implicit solvent model and the study of the alanine dipeptide and discrimination of misfolded structures of proteins.

  Proteins 20020401

• Regional muscle and adipose tissue amino acid metabolism in lean and obese women.

  American journal of physiology. Endocrinology and metabolism 20020401

• Physiological roles of free D- and L-alanine in the crayfish Procambarus clarkii with special reference to osmotic and anoxic stress responses.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020401

• Synthesis of (S)-3-(1-hydroxy-p-carboran-12-yl)alanine, a novel hydrophobic tyrosine-mimetic for peptides.

  Peptides 20020401

• Substitution of cysteine for a conserved alanine residue in the catalytic center of type II iodothyronine deiodinase alters interaction with reducing cofactor.

  Endocrinology 20020401

• Comparative efficacy between the glycoprotein IIb/IIIa antagonists roxifiban and orbofiban in inhibiting platelet responses in flow models of thrombosis.

  Journal of cardiovascular pharmacology 20020401

• Elucidation of vasoactive intestinal peptide pharmacophore for VPAC(1) receptors in human, rat, and guinea pig.

  The Journal of pharmacology and experimental therapeutics 20020401

• Analysis of serine proteinase-inhibitor interaction by alanine shaving.

  Protein science : a publication of the Protein Society 20020401

• Dissection of the conduit for allosteric control of carbamoyl phosphate synthetase by ornithine.

  Archives of biochemistry and biophysics 20020401

• Heterologous expression of an endogenous rat cytochrome b(5)/cytochrome b(5) reductase fusion protein: identification of histidines 62 and 85 as the heme axial ligands.

  Archives of biochemistry and biophysics 20020401

• Probing the proton channel and the retinal binding site of Natronobacterium pharaonis sensory rhodopsin II.

  Biophysical journal 20020401

• Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight.

  Diabetes 20020401

• Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020401

• Selective intranuclear redistribution of PPAR isoforms by RXR alpha.

  Molecular endocrinology (Baltimore, Md.) 20020401

• Catalytic mechanism of beta-amylase from Bacillus cereus var. mycoides: chemical rescue of hydrolytic activity for a catalytic site mutant (Glu367-->Ala) by azide.

  Journal of biochemistry 20020401

• Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma2 (PPARgamma2) is associated with higher levels of total cholesterol and LDL-cholesterol in male caucasian type 2 diabetes patients.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20020401

• Effect of diet supplementation with l-carnitine on hepatic catabolism of l-alanine in rats.

  Acta pharmacologica Sinica 20020401

• Chemical shift-based constraints for solution structure determination of paramagnetic low-spin heme proteins with bis-His and His-CN axial ligands: the cases of oxidized cytochrome b(5) and Met80Ala cyano-cytochrome c.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20020401

• Iron-sulfur cluster biosynthesis: characterization of Schizosaccharomyces pombe Isa1.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20020401

• A novel theory on the origin of the genetic code: a GNC-SNS hypothesis.

  Journal of molecular evolution 20020401

• Short- and long-term effects of p-ethynylphenylalanine on brain serotonin levels.

  Neurochemical research 20020401

• Environmental fate of metalaxyl and chlorothalonil applied to a bentgrass putting green under southern California climatic conditions.

  Pest management science 20020401

• Release of excitatory amino acids in the penumbra of a focal cortical necrosis.

  Journal of neurotrauma 20020401

• Identification of single amino acid residues essential for the binding of lipopolysaccharide (LPS) to LPS binding protein (LBP) residues 86-99 by using an Ala-scanning library.

  Journal of peptide science : an official publication of the European Peptide Society 20020401

• Long-term rebamipide therapy improves Helicobacter pylori-associated chronic gastritis.

  Digestive diseases and sciences 20020401

• New materials for ESR dosimetry.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20020401

• A study of the substrate specificity of Na+-dependent and Na+-independent neutral amino acid transport systems in dog intestinal brush-border membrane vesicles using L-alanine analogues.

  The Journal of pharmacy and pharmacology 20020401

• On the mechanism of the inhibition of Na(+), K(+)-ATPase activity caused by homocysteine.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20020401

• Obtaining molecular and structural information from 13C-14N systems with 13C FIREMAT experiments.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20020401

• Effects of orally active glycoprotein IIb/IIIa antagonists on platelet CD40 ligand (CD154) expression and platelet-heteroaggregate formation.

  Thrombosis research 20020401

• Variation in the fatty acid binding protein 2 gene is not associated with markers of metabolic syndrome in patients with coronary heart disease.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20020401

• An N-terminal arginine-rich cluster and a proline-alanine-threonine repeat region determine the cellular localization of the herpes simplex virus type 1 ICP34.5 protein and its ligand, protein phosphatase 1.

  The Journal of biological chemistry 20020329

• Racemic amino acids from the ultraviolet photolysis of interstellar ice analogues.

  Nature 20020328

• Intact carbohydrate structures as part of the melanoidin skeleton.

  Journal of agricultural and food chemistry 20020327

• Role of nucleotidyl transferase motif V in strand joining by chlorella virus DNA ligase.

  The Journal of biological chemistry 20020322

• Conserved residues in domain Ia are required for the reaction of Escherichia coli DNA ligase with NAD+.

  The Journal of biological chemistry 20020322

• A novel serine-rich motif in the intercellular adhesion molecule 3 is critical for its ezrin/radixin/moesin-directed subcellular targeting.

  The Journal of biological chemistry 20020322

• Specificity determinants in MAPK signaling to transcription factors.

  The Journal of biological chemistry 20020322

• Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner.

  The Journal of biological chemistry 20020322

• Bacterial lipopolysaccharide down-regulates expression of GTP cyclohydrolase I feedback regulatory protein.

  The Journal of biological chemistry 20020322

• Dipeptidyl peptidase with strict substrate specificity of an anaerobic periodontopathogen Porphyromonas gingivalis.

  FEMS microbiology letters 20020319

• Hairpin versus extended DNA binding of a substituted beta-alanine linked polyamide.

  Journal of the American Chemical Society 20020313

• Alcaligenes xylosoxidans dissimilatory nitrite reductase: alanine substitution of the surface-exposed histidine 139l ligand of the type 1 copper center prevents electron transfer to the catalytic center.

  Biochemistry 20020312

• Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin.

  The Journal of biological chemistry 20020308

• Modulation of hormone-sensitive lipase and protein kinase A-mediated lipolysis by perilipin A in an adenoviral reconstituted system.

  The Journal of biological chemistry 20020308

• The SANT domain of Ada2 is required for normal acetylation of histones by the yeast SAGA complex.

  The Journal of biological chemistry 20020308

• Mechanisms of the protective effect of L-alanine to D-galactosamine-induced hepatocellular injury: comparative studies of L-alanine and pyruvate.

  Biochemical and biophysical research communications 20020308

• Mutational analysis of a mammalian reovirus mRNA capping enzyme.

  Biochemical and biophysical research communications 20020308

• Adding L-3-(2-Naphthyl)alanine to the genetic code of E. coli.

  Journal of the American Chemical Society 20020306

• The role of SmpB protein in trans-translation.

  FEBS letters 20020306

• Functional evidence for D- and T-loop interactions in tmRNA.

  FEBS letters 20020306

• Structural requirements for high-affinity heparin binding: alanine scanning analysis of charged residues in the C-terminal domain of human extracellular superoxide dismutase.

  Biochemistry 20020305

• Single replacement constructs of all hydroxyl, basic, and acidic amino acids identify new function and structure-sensitive regions of the mitochondrial phosphate transport protein.

  Biochemistry 20020305

• Enhancement of skin permeation of miconazole by phospholipid and dodecyl 2-(N,N-dimethyl amino)propionate (DDAIP).

  International journal of pharmaceutics 20020302

• Anchoring of surface proteins to the cell wall of Staphylococcus aureus. Cysteine 184 and histidine 120 of sortase form a thiolate-imidazolium ion pair for catalysis.

  The Journal of biological chemistry 20020301

• Molecular determinants of high affinity binding to group III metabotropic glutamate receptors.

  The Journal of biological chemistry 20020301

• Identification of structural features in the G-protein regulatory motif required for regulation of heterotrimeric G-proteins.

  The Journal of biological chemistry 20020301

• Fetal hepatic and umbilical uptakes of glucogenic substrates during a glucagon-somatostatin infusion.

  American journal of physiology. Endocrinology and metabolism 20020301

• Modulation of cyanoalanine synthase and O-acetylserine (thiol) lyases A and B activity by beta-substituted alanyl and anion inhibitors.

  Journal of experimental botany 20020301

• Protein kinase D is a downstream target of protein kinase Ctheta.

  Biochemical and biophysical research communications 20020301

• l-[1-(13)C]Alanine is a useful substance for the evaluation of liver function.

  The Journal of surgical research 20020301

• Mutation A1555G in the 12S rRNA gene and its epidemiological importance in German, Hungarian, and Polish patients.

  Human mutation 20020301

• Serotonergic attenuation of the reinforcing and neurochemical effects of cocaine in squirrel monkeys.

  The Journal of pharmacology and experimental therapeutics 20020301

• Nepenthes insignis uses a C2-portion of the carbon skeleton of L-alanine acquired via its carnivorous organs, to build up the allelochemical plumbagin.

  Phytochemistry 20020301

• Free amino acids in claw muscle and haemolymph from Australian freshwater crayfish at different stages of the moult cycle.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020301

• New stochastic strategy to analyze helix folding.

  Biophysical journal 20020301

• Striatal AMPA receptor binding is unaltered in the MPTP-lesioned macaque model of Parkinson's disease and dyskinesia.

  Experimental neurology 20020301

• A novel Ala(-3)Thr mutation in the signal peptide of human luteinizing hormone beta-subunit: potentiation of the inositol phosphate signalling pathway and attenuation of the adenylate cyclase pathway by recombinant variant hormone.

  Molecular human reproduction 20020301

• The proline 12 alanine substitution in the peroxisome proliferator--activated receptor-gamma2 gene is associated with lower lipoprotein lipase activity in vivo.

  Diabetes 20020301

• Association between a novel variant of the human type 2 deiodinase gene Thr92Ala and insulin resistance: evidence of interaction with the Trp64Arg variant of the beta-3-adrenergic receptor.

  Diabetes 20020301

• Glutamine: an anaplerotic precursor.

  Nutrition (Burbank, Los Angeles County, Calif.) 20020301

• Combined effects of fasting and alanine on liver function recovery after cold ischemia.

  Transplant international : official journal of the European Society for Organ Transplantation 20020301

• Evaluation of a device for attenuation of electron release from dental restorations in a therapeutic radiation field.

  The Journal of prosthetic dentistry 20020301

• Transthyretin Thr60Ala Appalachian-type mutation in a Japanese family with familial amyloidotic polyneuropathy.

  Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20020301

• Solution structure of a phage-derived peptide antagonist in complex with vascular endothelial growth factor.

  Journal of molecular biology 20020222

• NMR structural study of two-disulfide variant of hen lysozyme: 2SS[6-127, 30-115]--a disulfide intermediate with a partly unfolded structure.

  Biochemistry 20020219

• Three subunits contribute amino acids to the active site of tetrameric adenylosuccinate lyase: Lys268 and Glu275 are required.

  Biochemistry 20020219

• A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility.

  Biochemistry 20020219

• Functional role of 'N' (nucleotide) and 'P' (phosphorylation) domain interactions in the sarcoplasmic reticulum (SERCA) ATPase.

  Biochemistry 20020219

• Consistent helicities from CD and template t/c data for N-templated polyalanines: progress toward resolution of the alanine helicity problem.

  Journal of the American Chemical Society 20020213

• Recombinant lysine:N(6)-hydroxylase: effect of cysteine-->alanine replacements on structural integrity and catalytic competence.

  Biochimica et biophysica acta 20020211

• Importance of Na,K-ATPase residue alpha 1-Arg544 in the segment Arg544-Asp567 for high-affinity binding of ATP, ADP, or MgATP.

  Biochemistry 20020205

• Conformational propensities of protein folding intermediates: distribution of species in the 1S, 2S, and 3S ensembles of the [C40A,C95A] mutant of bovine pancreatic ribonuclease A.

  Biochemistry 20020205

• A single glycine mutation in the equilibrative nucleoside transporter gene, hENT1, alters nucleoside transport activity and sensitivity to nitrobenzylthioinosine.

  Biochemistry 20020205

• Surface aspartate residues are essential for the stability of colicin A P-domain: a mechanism for the formation of an acidic molten-globule.

  Biochemistry 20020205

• Interactions between heme d and heme b595 in quinol oxidase bd from Escherichia coli: a photoselection study using femtosecond spectroscopy.

  Biochemistry 20020205

• Movement of the iron-sulfur subunit beyond the ef loop of cytochrome b is required for multiple turnovers of the bc1 complex but not for single turnover Qo site catalysis.

  The Journal of biological chemistry 20020201

• Effects of pentylenetetrazole and glutamate on metabolism of [U-(13)C]glucose in cultured cerebellar granule neurons.

  Neurochemistry international 20020201

• A potent human immunodeficiency virus type 1 protease inhibitor, UIC-94003 (TMC-126), and selection of a novel (A28S) mutation in the protease active site.

  Journal of virology 20020201

• Renal substrate exchange and gluconeogenesis in normal postabsorptive humans.

  American journal of physiology. Endocrinology and metabolism 20020201

• Chimaeric gonadotropin-releasing hormone (GnRH) peptides with improved affinity for the catfish (Clarias gariepinus) GnRH receptor.

  The Biochemical journal 20020201

• Hydration effects of heparin on antithrombin probed by osmotic stress.

  Biophysical journal 20020201

• C-deuterated alanine: a new label to study membrane protein structure using site-specific infrared dichroism.

  Biophysical journal 20020201

• Structure of the imipenem-hydrolyzing class A beta-lactamase SME-1 from Serratia marcescens.

  Acta crystallographica. Section D, Biological crystallography 20020201

• Conserved cysteine residues in the extracellular loop of the human P2X(1) receptor form disulfide bonds and are involved in receptor trafficking to the cell surface.

  Molecular pharmacology 20020201

• Binding characteristics of cetirizine and levocetirizine to human H(1) histamine receptors: contribution of Lys(191) and Thr(194).

  Molecular pharmacology 20020201

• Inclusion of low amounts of fructose with an intraduodenal glucose load markedly reduces postprandial hyperglycemia and hyperinsulinemia in the conscious dog.

  Diabetes 20020201

• Positional candidate cloning of a QTL in dairy cattle: identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition.

  Genome research 20020201

• EPR dosimetric properties of 2-methylalanine: EPR, ENDOR and FT-EPR investigations.

  Radiation research 20020201

• Unraveling hot spots in binding interfaces: progress and challenges.

  Current opinion in structural biology 20020201

• Relation between glutamine, branched-chain amino acids, and protein metabolism.

  Nutrition (Burbank, Los Angeles County, Calif.) 20020201

• Biological properties of the novel fungicide cyazofamid against Phytophthora infestans on tomato and Pseudoperonospora cubensis on cucumber.

  Pest management science 20020201

• Effect of rebamipide in treatment of Helicobacter pylori-associated duodenal ulcer: attenuation of chemokine expression and nitrosative damage.

  Digestive diseases and sciences 20020201

• Substitution of Gly-548 to Ala in the substrate binding pocket of prothrombin Perijá leads to the loss of thrombin proteolytic activity.

  Thrombosis and haemostasis 20020201

• Transforming growth factor beta receptor 1 polyalanine polymorphism and exon 5 mutation analysis in breast and ovarian cancer.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20020201

• Displacement study on a vancomycin-based stationary phase using N-acetyl-D-alanine as a competing agent.

  Journal of chromatographic science 20020201

• Conformational investigation of alpha,beta-dehydropeptides. X. Molecular and crystal structure of Ac-DeltaAla-NMe2 compared with those of Ac-L-Ala-NMe2, Ac-DL-Ala-NMe2 and other dimethylamides.

  The journal of peptide research : official journal of the American Peptide Society 20020201

• Effects of potassium and glutamine on metabolism of glucose in astrocytes.

  Neurochemical research 20020201

• Evaluation of circulating levels and renal clearance of natural amino acids in patients with Cushing's disease.

  Journal of endocrinological investigation 20020201

• The activity of leukocyte NADPH oxidase: regulation by p47PHOX cysteine and serine residues.

  Antioxidants & redox signaling 20020201

• [Rebamipide].

  Nihon rinsho. Japanese journal of clinical medicine 20020201

• Plasma lysine concentration and availability of 2-ketoglutarate in liver mitochondria.

  Journal of inherited metabolic disease 20020201

• Trienomycin G, a new inhibitor of nitric oxide production in microglia cells, from Streptomyces sp. 91614.

  The Journal of antibiotics 20020201

• Antitumor benzothiazoles. 16. Synthesis and pharmaceutical properties of antitumor 2-(4-aminophenyl)benzothiazole amino acid prodrugs.

  Journal of medicinal chemistry 20020131

• A site-directed mutagenesis analysis of tNOX functional domains.

  Biochimica et biophysica acta 20020131

• Charge conversion enables quantification of the proximity between a normally-neutral mu-conotoxin (GIIIA) site and the Na+ channel pore.

  FEBS letters 20020130

• A ruthenium(II) tris(bipyridyl) amino acid: synthesis and direct incorporation into an alpha-helical peptide by solid-phase synthesis.

  Inorganic chemistry 20020128

• A conserved sequence within the propeptide domain of membrane type 1 matrix metalloproteinase is critical for function as an intramolecular chaperone.

  The Journal of biological chemistry 20020125

• Mapping the anthrax protective antigen binding site on the lethal and edema factors.

  The Journal of biological chemistry 20020125

• Specific and dual antagonists of alpha(4)beta(1) and alpha(4)beta(7) integrins.

  Bioorganic & medicinal chemistry letters 20020121

• An improved procedure for the synthesis of branched polyethylene glycols (PEGs) with the reporter dipeptide Met-betaAla for protein conjugation.

  Bioorganic & medicinal chemistry letters 20020121

• Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor.

  Biochemistry 20020115

• Two glutamate residues, Glu 208 alpha and Glu 197 beta, are crucial for phosphorylation and dephosphorylation of the active-site histidine residue in succinyl-CoA synthetase.

  Biochemistry 20020115

• Structural features underlying the multisite phosphorylation of the A domain of the NF-AT4 transcription factor by protein kinase CK1.

  Biochemistry 20020115

• Environmental behavior of the chiral acetamide pesticide metalaxyl: enantioselective degradation and chiral stability in soil.

  Environmental science & technology 20020115

• Computational alanine scanning of the 1:1 human growth hormone-receptor complex.

  Journal of computational chemistry 20020115

• Protein repair methyltransferase from the hyperthermophilic archaeon Pyrococcus furiosus. Unusual methyl-accepting affinity for D-aspartyl and N-succinyl-containing peptides.

  The Journal of biological chemistry 20020111

• Structural studies of porcine myeloid antibacterial peptide PMAP-23 and its analogues in DPC micelles by NMR spectroscopy.

  Biochemical and biophysical research communications 20020111

• Differential effect of brefeldin A on the palmitoylation of surfactant protein C proprotein mutants.

  Biochemical and biophysical research communications 20020111

• Differing substrate specificities of members of the DYRK family of arginine-directed protein kinases.

  FEBS letters 20020102

• Effect of rebamipide on cell death induced by combined treatment of mild heat shock and quercetin in RGM-1 cells: a role for HSP70 induction.

  Pharmacology 20020101

• Troglitazone inhibits glutamine metabolism in rat mesangial cells.

  American journal of physiology. Endocrinology and metabolism 20020101

• Cleavage of the iron-methionine bond in c-type cytochromes: crystal structure of oxidized and reduced cytochrome c(2) from Rhodopseudomonas palustris and its ammonia complex.

  Protein science : a publication of the Protein Society 20020101

• Competing modes of self-association in the regulatory domains of Bruton's tyrosine kinase: intramolecular contact versus asymmetric homodimerization.

  Protein science : a publication of the Protein Society 20020101

• A cavity-forming mutation in insulin induces segmental unfolding of a surrounding alpha-helix.

  Protein science : a publication of the Protein Society 20020101

• Amino acid transport by intestinal brush border vesicles of a marine fish, Boops salpa.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020101

• Exploratory studies of ab initio protein structure prediction: multiple copy simulated annealing, AMBER energy functions, and a generalized born/solvent accessibility solvation model.

  Proteins 20020101

• Stereoselective degradation of metalaxyl and metalaxyl-M in soil and sunflower plants.

  Chirality 20020101

• Effects of replacement of prolines with alanines on the catalytic activity and thermostability of inorganic pyrophosphatase from thermophilic bacterium PS-3.

  Journal of biochemistry 20020101

• The association of Ala45Thr polymorphism in NeuroD with child-onset Type 1a diabetes in Japanese.

  Diabetes research and clinical practice 20020101

• Use of scanning mutagenesis to delineate structure-function relationships in G protein alpha subunits.

  Methods in enzymology 20020101

• MECP2 mutation in a boy with language disorder and schizophrenia.

  The American journal of psychiatry 20020101

• Regulation of carbon utilization by sulfur availability in Escherichia coli and Salmonella typhimurium.

  Microbiology (Reading, England) 20020101

• Chiral separation by electrokinetic capillary chromatography using newly synthesized linear polymers containing L-amino acid moieties.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20020101

• Synthesis of N-[2-(1-piperidinyl)ethyl]benzamides.

  Chemical & pharmaceutical bulletin 20020101

• [Effect of antiulcer agents on the urea breath test--Comparison between rebamipide and ecabet sodium].

  Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20020101

• Effects of cyclosporine A and prednisone treatment on mixed meal disposition in dogs with hepatic denervation.

  JPEN. Journal of parenteral and enteral nutrition 20020101

• Characterization of the aryl hydrocarbon receptor repressor gene and association of its Pro185Ala polymorphism with micropenis.

  Teratology 20020101

• The -9Ala/-9Val polymorphism in the mitochondrial targeting sequence of the manganese superoxide dismutase gene (MnSOD) is associated with age among Hispanics with colorectal carcinoma.

  Oncology reports 20020101

• Reduced lipolysis as possible cause for greater weight gain in subjects with the Pro12Ala polymorphism in PPARgamma2?

  Diabetologia 20020101

• Formation of D-alanyl-lipoteichoic acid is required for adhesion and virulence of Listeria monocytogenes.

  Molecular microbiology 20020101

• Mitochondrial genetic variants and Alzheimer disease: a case-control study of the T4336C and G5460A variants.

  Alzheimer disease and associated disorders 20020101

• The alanine-scanning mutagenesis of Dictyostelium myosin II at the ionic interface with actin.

  Results and problems in cell differentiation 20020101

• Proton nuclear magnetic resonance spectral profiles of urine from children and adolescents with type 1 diabetes.

  Clinical chemistry 20020101

• Presence of the 5,10-methylenetetrahydrofolate reductase C677T mutation in Puerto Rican patients with neural tube defects.

  Journal of child neurology 20020101

• PPARgamma2 pro12Ala polymorphism and insulin resistance in Japanese hypertensive patients.

  Hypertension research : official journal of the Japanese Society of Hypertension 20020101

• [A case of rebamipide-induced pneumonitis].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20020101

• Random peptide bacteriophage display as a probe for urokinase receptor ligands.

  Biological chemistry 20020101

• A spatial model of the glycine site of the NR1 subunit of NMDA-receptor and ligand docking.

  Doklady. Biochemistry and biophysics 20020101

• [Kinetic characteristics of luminol chemiluminescence caused by chloramine compounds].

  Biofizika 20020101

• Methylthioadenosine phosphorylase as target for chemoselective treatment of T-cell acute lymphoblastic leukemic cells.

  Blood cells, molecules & diseases 20020101

• [Study on in vitro killing activity of DAAO/D-Ala system to K562e cells].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20020101

• Epidermal growth factor regulation of system L alanine transport in undifferentiated and differentiated intestinal Caco-2 cells.

  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20020101

• Vicine and convicine in common vetch (Vicia sativa) seeds enhance beta-cyanoalanine toxicity in male broiler chicks.

  International journal of toxicology 20020101

• Effects of a new excitotoxic amino acid, dysiherbaine, on cultured Müller cells.

  Japanese journal of ophthalmology 20020101

• Investigating the tolerance of coiled-coil peptides to nonheptad sequence inserts.

  Journal of structural biology 20020101

• The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists.

  The pharmacogenomics journal 20020101

• Specific intraluminal nutrients alter mucosal blood flow during gut ischemia/reperfusion.

  JPEN. Journal of parenteral and enteral nutrition 20020101

• Interaction of the Yersinia pestis type III regulatory proteins LcrG and LcrV occurs at a hydrophobic interface.

  BMC microbiology 20020101

• Comparison of the secretory properties of four insulin-secreting cell lines.

  Endocrine research 20020101

• Application of 15N to the study of hepatic nitrogen metabolism.

  Advances in enzyme regulation 20020101

• Alanine reverses the inhibitory effect of phenylalanine on acetylcholinesterase activity.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

• Mitochondrial DNA A4336G mutation in Alzheimer's and Parkinson's diseases.

  European neurology 20020101

• Room-temperature synthesis of L-alanine using the alanine dehydrogenase of the hyperthermophilic archaeon Archaeoglobus fulgidus.

  Biotechnology progress 20020101

• [Polymorphism A/G in position +49 of CTLA4 exon 1 in multiple sclerosis in Russians].

  Molekuliarnaia biologiia 20020101

• [Dependence of mode of DNA binding to benzo crown derivatives of actinocin on the size and distance from the chromophore of crown fragments].

  Molekuliarnaia biologiia 20020101

• [Hyperhomocysteinaemia in a coeliac disease heterozygote for the two common mutations (677C->T and 1298A->C) of the methylenetetrahydrofolate reductase gene. Case report].

  Medycyna wieku rozwojowego 20020101

• Intronic mutation in the growth hormone receptor gene in a Peruvian girl with Laron syndrome.

  Journal of pediatric endocrinology & metabolism : JPEM 20020101

• Novel mutation involving the translation initiation codon of the growth hormone receptor gene (GHR) in a patient with Laron syndrome.

  Journal of pediatric endocrinology & metabolism : JPEM 20020101

• Molecular analysis of Frasier syndrome: mutation in the WT1 gene in a girl with gonadal dysgenesis and nephronophthisis.

  Journal of pediatric endocrinology & metabolism : JPEM 20020101

• Candida albicans and Saccharomyces cerevisiae expressing ALA1/ALS5 adhere to accessible threonine, serine, or alanine patches.

  Cell communication & adhesion 20020101

• Circular dichroism of amino acid films in UV-VUV region.

  Enantiomer 20020101

• Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is associated with increased leptin levels in women with type-2 diabetes mellitus.

  Hormone research 20020101

• Avoiding proteasomal processing: the case of EBNA1.

  Current topics in microbiology and immunology 20020101

• Electrospray ionization mass spectrometry of serine/alanine conjugated 5'-UMP and 3',5'-dithymidine phosphoramidates.

  Rapid communications in mass spectrometry : RCM 20020101

• Intercomparison of absorbed dose to water measurements for 60Co gamma rays using Fricke, alanine and radiochromic dye film dosimetry.

  Radiation protection dosimetry 20020101

• Alanine response to proton beams in the 1.6-6.1 MeV energy range.

  Radiation protection dosimetry 20020101

• Caramelization of maltose solution in presence of alanine.

  Amino acids 20020101

• Glutamine supplementation fails to affect muscle protein kinetics in critically ill patients.

  JPEN. Journal of parenteral and enteral nutrition 20020101

• Transfection of p27(Kip1) threonine residue 187 mutant type gene, which is not influenced by ubiquitin-mediated degradation, induces cell cycle arrest in oral squamous cell carcinoma cells.

  Oncology 20020101

• gamma-Glutamyltranspeptidase and gamma-glutamyl peptide ligases: fluorophosphonate and phosphonodifluoromethyl ketone analogs as probes of tetrahedral transition state and gamma-glutamyl-phosphate intermediate.

  Methods in enzymology 20020101

• Haplotype analysis of the PPARgamma Pro12Ala and C1431T variants reveals opposing associations with body weight.

  BMC genetics 20020101

• REDOR-based heteronuclear dipolar correlation experiments in multi-spin systems: rotor-encoding, directing, and multiple distance and angle determination.

  Solid state nuclear magnetic resonance 20020101

• [Mutational analysis of the conserved motif of the Arda anti-restriction protein encoded by self-transmissible IncI plasmid ColIb-p9].

  Molekuliarnaia biologiia 20020101

• Lysosomotropic N,N- dimethyl alpha-aminoacid N-alkyl esters and their quaternary ammonium salts as plasma membrane and mitochondrial ATPases inhibitors.

  Cellular & molecular biology letters 20020101

• F0 cysteine, bCys21, in the Escherichia coli ATP synthase is involved in regulation of potassium uptake and molecular hydrogen production in anaerobic conditions.

  Bioscience reports 20020101

• [Clinical picture of patients with Huntington's disease in relation to the number of trinucleotide CAG repeats in IT-15 gene].

  Neurologia i neurochirurgia polska 20020101

• Effects of two different formulations of metalaxyl on their residues in cucumber.

  Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen) 20020101

• Detection of resistance to fungicides, mating types and fitness of Phytophthora infestans in Hebei, China.

  Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen) 20020101

• [Mutations of MTHFR, MTR, MTRR genes as high risk factors for neural tube defects].

  Medycyna wieku rozwojowego 20020101

• [Kinetics of trypsin-catalyzed hydrolysis of some arginine-containing peptide methyl esters].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101

• Mechanisms for intragenic complementation at the human argininosuccinate lyase locus.

  Biochemistry 20011225

• Kinetic and mechanistic studies of penicillin-binding protein 2x from Streptococcus pneumoniae.

  Biochemistry 20011225

• Characterization of the 1H-cyclopentapyrimidine-2,4(1H,3H)-dione derivative (S)-CPW399 as a novel, potent, and subtype-selective AMPA receptor full agonist with partial desensitization properties.

  Journal of medicinal chemistry 20011220

• Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis.

  The Journal of biological chemistry 20011214

• ATP synthase F(1) sector rotation. Defective torque generation in the beta subunit Ser-174 to Phe mutant and its suppression by second mutations.

  The Journal of biological chemistry 20011214

• Alternatively folded choriogonadotropin analogs. Implications for hormone folding and biological activity.

  The Journal of biological chemistry 20011214

• Characterization of posttranslational formylglycine formation by luminal components of the endoplasmic reticulum.

  The Journal of biological chemistry 20011214

• Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation.

  The Journal of biological chemistry 20011214

• Inhibition of tyrosine phenol-lyase from Citrobacter freundii by 2-azatyrosine and 3-azatyrosine.

  Biochemistry 20011211

• Recognition of cello-oligosaccharides by a family 17 carbohydrate-binding module: an X-ray crystallographic, thermodynamic and mutagenic study.

  Journal of molecular biology 20011207

• A point mutant of human sphingosine kinase 1 with increased catalytic activity.

  FEBS letters 20011207

• Time-resolved infrared study of the helix-coil transition using (13)C-labeled helical peptides.

  Journal of the American Chemical Society 20011205

• Manganese superoxide dismutase alanine-to-valine polymorphism at codon 16 and lung cancer risk.

  Journal of the National Cancer Institute 20011205

• Mutational analysis of the N-terminus of Moloney murine leukemia virus integrase.

  Virology 20011205

• Identification of the proton pathway in bacterial reaction centers: decrease of proton transfer rate by mutation of surface histidines at H126 and H128 and chemical rescue by imidazole identifies the initial proton donors.

  Biochemistry 20011204

• Potential energy surfaces for the gas-phase interaction between alpha-alanine and alkali metal Ions (Li+, Na+, K+). A density functional study.

  Inorganic chemistry 20011203

• p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis.

  The EMBO journal 20011203

• Nuclear export of phosphorylated C/EBPbeta mediates the inhibition of albumin expression by TNF-alpha.

  The EMBO journal 20011203

• Structure of epitopes recognized by the antibodies to alpha(181-192) peptides of neuronal nicotinic acetylcholine receptors: extrapolation to the structure of acetylcholine-binding domain.

  Journal of neuroimmunology 20011203

• Identification of a region in G protein gamma subunits conserved across species but hypervariable among subunit isoforms.

  Protein science : a publication of the Protein Society 20011201

• Identification of residues critical for metallo-beta-lactamase function by codon randomization and selection.

  Protein science : a publication of the Protein Society 20011201

• Antifreeze protein from shorthorn sculpin: identification of the ice-binding surface.

  Protein science : a publication of the Protein Society 20011201

• Genetic analysis of the Epstein-Barr virus-coded leader protein EBNA-LP as a co-activator of EBNA2 function.

  The Journal of general virology 20011201

• Effect of mutation of a calmodulin binding site on Ca2+ regulation of inositol trisphosphate receptors.

  The Biochemical journal 20011201

• Genetic variation in glycoprotein IIb/IIIa (GPIIb/IIIa) as a determinant of the responses to an oral GPIIb/IIIa antagonist in patients with unstable coronary syndromes.

  Blood 20011201

• Antibodies against the carboxyl-terminal end of the Trypanosoma cruzi ribosomal P proteins are pathogenic.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011201

• Growth hormone and insulin-like growth factor-I counteracts established steroid catabolism in rats by effects on hepatic amino-N degradation.

  Journal of hepatology 20011201

• Assimilation and catabolism of dispensable and indispensable free amino acids in post-larval Senegal sole (Solea senegalensis).

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20011201

• Differences in neurotransmitter synthesis and intermediary metabolism between glutamatergic and GABAergic neurons during 4 hours of middle cerebral artery occlusion in the rat: the role of astrocytes in neuronal survival.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20011201

• Antifungal alkyl amino alcohols from the tropical marine sponge Haliclona n. sp.

  Journal of natural products 20011201

• Ala-His mediated peptide bond formation revisited.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20011201

• Heat labile ribonuclease HI from a psychrotrophic bacterium: gene cloning, characterization and site-directed mutagenesis.

  Protein engineering 20011201

• Active transport of alanine by the neutral amino-acid exchanger ASCT1.

  Canadian journal of physiology and pharmacology 20011201

• Purification of an aminopeptidase preferentially releasing N-terminal alanine from cucumber leaves and its identification as a plant aminopeptidase N.

  Bioscience, biotechnology, and biochemistry 20011201

• Urea synthesis in patients with chronic pancreatitis: relation to glucagon secretion and dietary protein intake.

  Clinical nutrition (Edinburgh, Scotland) 20011201

• Systematic mutational analysis of the amino-terminal domain of the Listeria monocytogenes ActA protein reveals novel functions in actin-based motility.

  Molecular microbiology 20011201

• Sodium absorption, volume control and potassium channels: in tribute to a great biologist.

  The Journal of membrane biology 20011201

• [Expression of D-animo acid oxidase gene in K562 cells and the cytotoxicity of D-alanine to the cells].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20011201

• Structural model of the catalytic core of carnitine palmitoyltransferase I and carnitine octanoyltransferase (COT): mutation of CPT I histidine 473 and alanine 381 and COT alanine 238 impairs the catalytic activity.

  The Journal of biological chemistry 20011130

• Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations.

  The Journal of biological chemistry 20011130

• The juxtamembrane sequence of cytochrome P-450 2C1 contains an endoplasmic reticulum retention signal.

  The Journal of biological chemistry 20011130

• The distal hinge of the reactive site loop and its proximity: a target to modulate plasminogen activator inhibitor-1 activity.

  The Journal of biological chemistry 20011130

• Identification and characterization of the DNA binding domain of CpG-binding protein.

  The Journal of biological chemistry 20011130

• Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation.

  The Journal of biological chemistry 20011130

• Asymmetric synthesis of [2,3-(13)C(2),(15)N]-4-benzyloxy-5,6-diphenyl-2,3,5,6-tetrahydro-4H-oxazine-2-one via lipase TL-mediated kinetic resolution of benzoin: general procedure for the synthesis of [2,3-(13)C(2),(15)N]-L-alanine.

  The Journal of organic chemistry 20011130

• A novel presenilin 2 gene mutation (D439A) in a patient with early-onset Alzheimer's disease.

  Neurology 20011127

• Alanine scanning mutagenesis of a type 1 insulin-like growth factor receptor ligand binding site.

  The Journal of biological chemistry 20011123

• Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.

  Biochemistry 20011120

• Mapping the ligand-binding site on the C5a receptor: arginine74 of C5a contacts aspartate282 of the C5a receptor.

  Biochemistry 20011120

• Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain.

  The Journal of biological chemistry 20011116

• Design and characterization of a highly selective peptide inhibitor of the small conductance calcium-activated K+ channel, SkCa2.

  The Journal of biological chemistry 20011116

• The viral CC chemokine-binding protein vCCI inhibits monocyte chemoattractant protein-1 activity by masking its CCR2B-binding site.

  The Journal of biological chemistry 20011116

• Single nucleotide polymorphism of human platelet-activating factor receptor impairs G-protein activation.

  The Journal of biological chemistry 20011116

• Multiple effects of aspartate mutant presenilin 1 on the processing and trafficking of amyloid precursor protein.

  The Journal of biological chemistry 20011116

• Asymmetric synthesis of gamma-keto-delta-lactam derivatives: application to the synthesis of a conformationally constrained surrogate of Ala-Ser dipeptide.

  The Journal of organic chemistry 20011116

• Simultaneous and functional binding of SmpB and EF-Tu-TP to the alanyl acceptor arm of tmRNA.

  Journal of molecular biology 20011116

• Theoretical study of the conformation of the lipoamide arm in a mutant H protein.

  Proteins 20011115

• A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families.

  JAMA 20011114

• Alanine-scanning of the 50's loop in the Clostridium beijerinckii flavodoxin: evaluation of additivity and the importance of interactions provided by the main chain in the modulation of the oxidation-reduction potentials.

  Biochemistry 20011113

• Zeaxanthin and menaquinone-7 biosynthesis in Sphingobacterium multivorum via the methylerythritol phosphate pathway.

  FEMS microbiology letters 20011113

• Molecular anatomy of CCR5 engagement by physiologic and viral chemokines and HIV-1 envelope glycoproteins: differences in primary structural requirements for RANTES, MIP-1 alpha, and vMIP-II Binding.

  Journal of molecular biology 20011109

• Experimental colitis decreases rat jejunal amino acid absorption: role of capsaicin sensitive primary afferents.

  Life sciences 20011109

• Adapting pharmacokinetic properties of a humanized anti-interleukin-8 antibody for therapeutic applications using site-specific pegylation.

  Cytokine 20011107

• A conformational switch in the inhibitory gamma-subunit of PDE6 upon enzyme activation by transducin.

  Biochemistry 20011106

• Long-range interactions in the dimer interface of ornithine decarboxylase are important for enzyme function.

  Biochemistry 20011106

• Structural and functional mapping of the thrombin domain involved in the binding to the platelet glycoprotein Ib.

  Biochemistry 20011106

• Identification and role of ionizing functional groups at the active center of Rhodotorula gracilis D-amino acid oxidase.

  FEBS letters 20011102

• Uptake of D-serine by synaptosomal P2 fraction isolated from rat brain.

  Synapse (New York, N.Y.) 20011101

• Plasma total homocysteine levels and the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene: a study in an Italian population with dementia.

  Mechanisms of ageing and development 20011101

• Native-state conformational dynamics of GART: a regulatory pH-dependent coil-helix transition examined by electrostatic calculations.

  Protein science : a publication of the Protein Society 20011101

• Structural analysis of mutants of high-affinity and low-affinity p-azophenylarsonate-specific antibodies generated by alanine scanning of heavy chain complementarity-determining region 2.

  Journal of immunology (Baltimore, Md. : 1950) 20011101

• pH and kinetic isotope effects in d-amino acid oxidase catalysis.

  European journal of biochemistry 20011101

• Influence of biotic and abiotic factors on dissipating metalaxyl in soil.

  Chemosphere 20011101

• The defective transforming phenotype of c-Jun Ala(63/73) is rescued by mutation of the C-terminal phosphorylation site.

  Oncogene 20011101

• Sibling-based association study of the PPARgamma2 Pro12Ala polymorphism and metabolic variables in Chinese and Japanese hypertension families: a SAPPHIRe study. Stanford Asian-Pacific Program in Hypertension and Insulin Resistance.

  Journal of molecular medicine (Berlin, Germany) 20011101

• Laboratory studies to assess the risk of development of resistance to zoxamide.

  Pest management science 20011101

• Comparison of vaginal aminopeptidase enzymatic activities in various animals and in humans.

  The Journal of pharmacy and pharmacology 20011101

• Increasing the hydrophobic interaction between terminal W-motifs enhances the stability of Salmonella typhimurium sialidase. A general strategy for the stabilization of beta-propeller protein fold.

  Protein engineering 20011101

• Adjacent cysteine residues as a redox switch.

  Protein engineering 20011101

• Sucrose transport through maltoporin mutants of Escherichia coli.

  Protein engineering 20011101

• Resolution of enantiomers of DL-amino acids on silica gel plates impregnated with optically pure (-)-quinine.

  Biomedical chromatography : BMC 20011101

• Mapping of IFN-beta epitopes important for receptor binding and biologic activation: comparison of results achieved using antibody-based methods and alanine substitution mutagenesis.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20011101

• Alanosine (UCSD).

  Current opinion in investigational drugs (London, England : 2000) 20011101

• Discovery of potent and selective peptide agonists at the GRP-preferring bombesin receptor (BB2).

  Journal of peptide science : an official publication of the European Peptide Society 20011101

• Comment on 'new infrared spectra and tautomeric studies of purine and alpha L-alanine with an innovative sampling technique.'.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20011101

• The large cytoplasmic loop of the glucose transporter GLUT1 is an essential structural element for function.

  Biological chemistry 20011101

• Mutation at the CK2 phosphorylation site on Cdc28 affects kinase activity and cell size in Saccharomyces cerevisiae.

  Molecular and cellular biochemistry 20011101

• Generation of mutants of CK2alpha which are dependent on the beta-subunit for catalytic activity.

  Molecular and cellular biochemistry 20011101

• A novel point mutation (C571T) in the tissue-non-specific alkaline phosphatase gene in a case of adult-type hypophosphatasia.

  Oral diseases 20011101

• Estimation of carbon-carbon bond lengths and medium-range internuclear distances by solid-state nuclear magnetic resonance.

  Journal of the American Chemical Society 20011031

• Steady-state and pre-steady-state kinetic analysis of Mycobacterium tuberculosis pantothenate synthetase.

  Biochemistry 20011030

• The polymorphism at codon 54 of the FABP2 gene increases fat absorption in human intestinal explants.

  The Journal of biological chemistry 20011026

• Ryanodine sensitizes the Ca(2+) release channel (ryanodine receptor) to Ca(2+) activation.

  The Journal of biological chemistry 20011026

• Heteronuclear recoupling in solid-state magic-angle-spinning NMR via overtone irradiation.

  Journal of the American Chemical Society 20011024

• An experimental and theoretical investigation of the chemical shielding tensors of (13)C(alpha) of alanine, valine, and leucine residues in solid peptides and in proteins in solution.

  Journal of the American Chemical Society 20011024

• Structural basis for the substrate specificity of the feruloyl esterase domain of the cellulosomal xylanase Z from Clostridium thermocellum.

  Biochemistry 20011023

• A role for aromatic amino acids in the binding of Xenopus ribosomal protein L5 to 5S rRNA.

  Biochemistry 20011023

• Role of cysteine residues in structural stability and function of a transmembrane helix bundle.

  The Journal of biological chemistry 20011019

• Antiviral activity and structural characteristics of the nonglycosylated central subdomain of human respiratory syncytial virus attachment (G) glycoprotein.

  The Journal of biological chemistry 20011019

• N-end rule specificity within the ubiquitin/proteasome pathway is not an affinity effect.

  The Journal of biological chemistry 20011019

• Activation of protein kinase D by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13.

  The Journal of biological chemistry 20011019

• Stimuli-responsive properties of conjugates of N-isopropylacrylamide-co-acrylic acid oligomers with alanine, glycine and serine mono-, di- and tri-peptides.

  Journal of controlled release : official journal of the Controlled Release Society 20011019

• A novel mutation in glial fibrillary acidic protein gene in a patient with Alexander disease.

  Neuroscience letters 20011019

• A helical arrangement of beta-substituents of dehydropeptides: synthesis and conformational study of sequential nona- and dodecapeptides possessing (Z)-beta-(1-naphthyl)dehydroalanine residues.

  Biopolymers 20011015

• Fumonisin B(1) induces apoptosis in LLC-PK(1) renal epithelial cells via a sphinganine- and calmodulin-dependent pathway.

  Toxicology and applied pharmacology 20011015

• Mapping of a region within the N terminus of Jak1 involved in cytokine receptor interaction.

  The Journal of biological chemistry 20011005

• Enantioselective synthesis of (2-pyridyl)alanines via catalytic hydrogenation and application to the synthesis of L-azatyrosine.

  Organic letters 20011004

• Dihedral angles of trialanine in D2O determined by combining FTIR and polarized visible Raman spectroscopy.

  Journal of the American Chemical Society 20011003

• Binding of correolide to the K(v)1.3 potassium channel: characterization of the binding domain by site-directed mutagenesis.

  Biochemistry 20011002

• Evidence for the involvement of Ala 166 in coupling Na(+) to sugar transport through the human Na(+)/glucose cotransporter.

  Biochemistry 20011002

• Production and specificity of monoclonal antibodies against nodularin conjugated through N-methyldehydrobutyrine.

  Toxicon : official journal of the International Society on Toxinology 20011001

• Aromatic di-alanine repeats (AdAR) are structural motifs characteristic of the soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) family.

  Proteins 20011001

• Analysis of the segmental stability of helical peptides by isotope-edited infrared spectroscopy.

  Proteins 20011001

• Evidence of separate pathways for lactate uptake and release by the perfused rat heart.

  American journal of physiology. Endocrinology and metabolism 20011001

• Identification of a region of strong discrimination in the pore of CFTR.

  American journal of physiology. Lung cellular and molecular physiology 20011001

• Evidence for altered hepatic gluconeogenesis in patients with cirrhosis using in vivo 31-phosphorus magnetic resonance spectroscopy.

  Gut 20011001

• Mutagenesis of the Dengue virus type 2 NS3 protein within and outside helicase motifs: effects on enzyme activity and virus replication.

  Journal of virology 20011001

• Double-blind placebo-controlled multicentre studies of rebamipide, a gastroprotective drug, in the treatment of functional dyspepsia with or without Helicobacter pylori infection.

  Alimentary pharmacology & therapeutics 20011001

• Acute effects of moderate dehydration on the hepatic conversion of amino nitrogen into urea nitrogen in healthy men.

  Clinical science (London, England : 1979) 20011001

• Rapid identification of Enterococcus durans and Enterococcus hirae by PCR with primers targeted to the ddl genes.

  Journal of microbiological methods 20011001

• Early photocycle kinetic behavior of the E46A and Y42F mutants of photoactive yellow protein: femtosecond spectroscopy.

  Biophysical journal 20011001

• Structural investigations of the active-site mutant Asn156Ala of outer membrane phospholipase A: function of the Asn-His interaction in the catalytic triad.

  Protein science : a publication of the Protein Society 20011001

• Tannins--a dietary problem for hand-reared grey partridge Perdix perdix after release?

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20011001

• The antioxidant effect of rebamipide on oxygen free radical production by H. pylori-activated human neutrophils: in comparison with N-acetylcysteine, ascorbic acid and glutathione.

  Pharmacological research 20011001

• Vicianin, prunasin, and beta-cyanoalanine in common vetch seed as sources of urinary thiocyanate in the rat.

  Journal of agricultural and food chemistry 20011001

• Bis(beta-alaninium) biphenyl-4,4'-disulfonate.

  Acta crystallographica. Section C, Crystal structure communications 20011001

• Structure and localization of cyclosporin synthetase, the key enzyme of cyclosporin biosynthesis in Tolypocladium inflatum.

  Archives of microbiology 20011001

• Protective effect of rebamipide on indomethacin-induced intestinal damage in rats.

  Journal of gastroenterology and hepatology 20011001

• Recent advances in the formation of the bacterial peptidoglycan monomer unit.

  Natural product reports 20011001

• Mutational analysis of conserved glycines 42 and 256 in Cephalosporium acremonium isopenicillin N synthase.

  Canadian journal of microbiology 20011001

• Energetic analysis of binding of progesterone and 5 beta-androstane-3,17-dione to anti-progesterone antibody DB3 using molecular dynamics and free energy calculations.

  Protein engineering 20011001

• Increased proteolytic resistance of ribonuclease A by protein engineering.

  Protein engineering 20011001

• NAD+-dependent DNA ligase encoded by a eukaryotic virus.

  The Journal of biological chemistry 20010928

• An essential function of Saccharomyces cerevisiae RNA triphosphatase Cet1 is to stabilize RNA guanylyltransferase Ceg1 against thermal inactivation.

  The Journal of biological chemistry 20010928

• Identification of a critical lysine residue in apolipoprotein B-100 that mediates noncovalent interaction with apolipoprotein(a).

  The Journal of biological chemistry 20010928

• Chromaffin cell F-actin disassembly and potentiation of catecholamine release in response to protein kinase C activation by phorbol esters is mediated through myristoylated alanine-rich C kinase substrate phosphorylation.

  The Journal of biological chemistry 20010928

• Molecular and cellular physiology of the dissociation of atrial natriuretic peptide from guanylyl cyclase a receptors.

  The Journal of biological chemistry 20010928

• Glu(191) and Asp(195) in rat mitochondrial processing peptidase beta subunit are involved in effective cleavage of precursor protein through interaction with the proximal arginine.

  Biochemical and biophysical research communications 20010928

• Catalase-peroxidase from synechocystis is capable of chlorination and bromination reactions.

  Biochemical and biophysical research communications 20010928

• Promoter-specific involvement of the FixJ receiver domain in transcriptional activation.

  Journal of molecular biology 20010928

• Temperature-dependent helix-coil transition of an alanine based peptide.

  Journal of the American Chemical Society 20010926

• Difference in cholesterol-binding and cytolytic activities between listeriolysin O and seeligeriolysin O: a possible role of alanine residue in tryptophan-rich undecapeptide.

  FEMS microbiology letters 20010925

• Cysteine substitutions reveal dual functions of the amino-terminal tail in cystic fibrosis transmembrane conductance regulator channel gating.

  The Journal of biological chemistry 20010921

• Hydrophobic residues Phe552, Phe554, Ile562, Leu566, and Ile574 are required for oligomerization of anthrax protective antigen.

  Biochemical and biophysical research communications 20010921

• Domain swing upon His to Ala mutation in nitrite reductase of Pseudomonas aeruginosa.

  Journal of molecular biology 20010921

• Two-dimensional (17)O multiple quantum magic-angle spinning NMR of organic solids.

  Journal of the American Chemical Society 20010919

• Sendai virus wild-type and mutant C proteins show a direct correlation between L polymerase binding and inhibition of viral RNA synthesis.

  Virology 20010915

• A method for defining binding sites involved in protein-protein interactions: analysis of the binding of plasminogen activator inhibitor 1 to the somatomedin domain of vitronectin.

  Analytical biochemistry 20010915

• Degradation signals in ErbB-2 dictate proteasomal processing and immunogenicity and resist protection by cis glycine-alanine repeat.

  Cellular immunology 20010915

• BACE2 functions as an alternative alpha-secretase in cells.

  The Journal of biological chemistry 20010907

• Electron spin resonance and fluorescence studies of the bound-state conformation of a model protein substrate to the chaperone SecB.

  The Journal of biological chemistry 20010907

• Targeting of EBNA1 for rapid intracellular degradation overrides the inhibitory effects of the Gly-Ala repeat domain and restores CD8+ T cell recognition.

  The Journal of biological chemistry 20010907

• Transmembrane domains 4 and 7 of the M(1) muscarinic acetylcholine receptor are critical for ligand binding and the receptor activation switch.

  The Journal of biological chemistry 20010907

• The role of the cysteine residues of ThiI in the generation of 4-thiouridine in tRNA.

  The Journal of biological chemistry 20010907

• Analysis of the minimal amyloid-forming fragment of the islet amyloid polypeptide. An experimental support for the key role of the phenylalanine residue in amyloid formation.

  The Journal of biological chemistry 20010907

• Characterization of loops of the yeast mitochondrial ADP/ATP carrier facing the cytosol by site-directed mutagenesis.

  Biochemical and biophysical research communications 20010907

• Role of Phe286 in the recognition mechanism of cyclomaltooligosaccharides (cyclodextrins) by Thermoactinomyces vulgaris R-47 alpha-amylase 2 (TVAII). X-ray structures of the mutant TVAIIs, F286A and F286Y, and kinetic analyses of the Phe286-replaced mutant TVAIIs.

  Carbohydrate research 20010907

• Quantum mechanics simulation of protein dynamics on long timescale.

  Proteins 20010901

• Effects of acute exercise on the gluconeogenic capacity of periportal and perivenous hepatocytes.

  Journal of applied physiology (Bethesda, Md. : 1985) 20010901

• The structure and domain organization of Escherichia coli isocitrate lyase.

  Acta crystallographica. Section D, Biological crystallography 20010901

• Structure of interleukin 4 mutant E9A suggests polar steering in receptor-complex formation.

  Acta crystallographica. Section D, Biological crystallography 20010901

• A pulse EPR study of longitudinal relaxation of the stable radical in gamma-irradiated L-alanine.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20010901

• Nitrogen source governs the patterns of growth and pristinamycin production in 'Streptomyces pristinaespiralis'.

  Microbiology (Reading, England) 20010901

• Is ischemia involved in the pathogenesis of murine cerebral malaria?

  The American journal of pathology 20010901

• Improved analysis of 1H-MR spectra in the presence of mobile lipids.

  Magnetic resonance in medicine 20010901

• Effect of arginine mutation of alanine-556 on DNA recognition of zinc finger protein Sp1.

  Bioorganic & medicinal chemistry 20010901

• The contribution of the methyl groups on thymine bases to binding specificity and affinity by alanine-rich mutants of the bZIP motif.

  Bioorganic & medicinal chemistry 20010901

• Tissues of the clawed frog Xenopus laevis contain two closely related forms of UDP-GlcNAc:alpha3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.

  Glycobiology 20010901

• In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zeta.

  Genetics 20010901

• The functional impact of Pgm amino acid polymorphism on glycogen content in Drosophila melanogaster.

  Genetics 20010901

• Association of gene polymorphism of polymeric immunoglobulin receptor and IgA nephropathy.

  Internal medicine (Tokyo, Japan) 20010901

• The Ccz1 protein interacts with Ypt7 GTPase during fusion of multiple transport intermediates with the vacuole in S. cerevisiae.

  Journal of cell science 20010901

• Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) gene in relation to insulin sensitivity among glucose tolerant caucasians.

  Diabetologia 20010901

• Construction of a Bacillus subtilis (natto) with high productivity of vitamin K2 (menaquinone-7) by analog resistance.

  Bioscience, biotechnology, and biochemistry 20010901

• Investigation of the dNTP-binding site of HIV-1 reverse transcriptase using photoreactive analogs of dNTP.

  Biochemistry. Biokhimiia 20010901

• Role of conservative residue Cys158 in the formation of an active photoprotein complex of obelin.

  Biochemistry. Biokhimiia 20010901

• Cold-active citrate synthase: mutagenesis of active-site residues.

  Protein engineering 20010901

• Encapsulation of PEG-urease/PEG-AlaDH enzyme system in erythrocyte.

  Artificial cells, blood substitutes, and immobilization biotechnology 20010901

• [Studies on hereditary deficiency of coagulation factor V].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20010901

• [A novel point mutation in the transmembrane domain of platelet glycoprotein IX gene identified in a Bernard-Soulier syndrome patient].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20010901

• Identification of inactivation determinants in the domain IIS6 region of high voltage-activated calcium channels.

  The Journal of biological chemistry 20010831

• Identification of functionally important amino-terminal arginines of Agrobacterium tumefaciens ADP-glucose pyrophosphorylase by alanine scanning mutagenesis.

  Biochemistry 20010828

• Cleavage of 3',5'-pyrophosphate-linked dinucleotides by ribonuclease A and angiogenin.

  Biochemistry 20010828

• Alanine metabolism in the perfused rat liver. Studies with (15)N.

  The Journal of biological chemistry 20010824

• Kinetic mechanism and regulation of myosin VI.

  The Journal of biological chemistry 20010824

• Selective cleavage of D-Ala-D-Lac by small molecules: re-sensitizing resistant bacteria to vancomycin.

  Science (New York, N.Y.) 20010824

• Enzymatic synthesis of aza-l-tyrosines.

  Bioorganic & medicinal chemistry letters 20010820

• Alanine-scanning mutagenesis of the sixth transmembrane segment of gastric H+,K+-ATPase alpha-subunit.

  The Journal of biological chemistry 20010817

• Species-specific differences in amino acid editing by class II prolyl-tRNA synthetase.

  The Journal of biological chemistry 20010817

• alpha-helix formation: discontinuous molecular dynamics on an intermediate-resolution protein model.

  Proteins 20010815

• The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.

  The EMBO journal 20010815

• Effects of alanine cluster mutations in the D12 subunit of vaccinia virus mRNA (guanine-N7) methyltransferase.

  Virology 20010815

• Functional groups required for the stability of yeast RNA triphosphatase in vitro and in vivo.

  The Journal of biological chemistry 20010810

• Loss of clumping factor B fibrinogen binding activity by Staphylococcus aureus involves cessation of transcription, shedding and cleavage by metalloprotease.

  The Journal of biological chemistry 20010810

• Distinct functional surface regions on ubiquitin.

  The Journal of biological chemistry 20010810

• Recognition of fibronectin by the platelet integrin alpha IIb beta 3 involves an extended interface with multiple electrostatic interactions.

  Biochemistry 20010807

• Pre-steady-state kinetic studies of Saccharomyces cerevisiae myristoylCoA:protein N-myristoyltransferase mutants identify residues involved in catalysis.

  Biochemistry 20010807

• Functional inactivation of the human guanylyl cyclase C receptor: modeling and mutation of the protein kinase-like domain.

  Biochemistry 20010807

• Short segment of human melanin-concentrating hormone that is sufficient for full activation of human melanin-concentrating hormone receptors 1 and 2.

  Biochemistry 20010807

• Mutations in the G-domain of elongation factor G from Thermus thermophilus affect both its interaction with GTP and fusidic acid.

  The Journal of biological chemistry 20010803

• Conformational change in the vinculin C-terminal depends on a critical histidine residue (His-906).

  The Journal of biological chemistry 20010803

• Isolation and characterisation of dipeptidyl peptidase IV from Prevotella loescheii ATCC 15930.

  Archives of oral biology 20010801

• Proline-induced hinges in transmembrane helices: possible roles in ion channel gating.

  Proteins 20010801

• Cooperative helix stabilization by complex Arg-Glu salt bridges.

  Proteins 20010801

• ESR dosimetry using inorganic materials: a case study of Li2CO3 and CaSO4:Dy as prospective dosimeters.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20010801

• Mechanism of fat-induced hepatic gluconeogenesis: effect of metformin.

  American journal of physiology. Endocrinology and metabolism 20010801

• Sulfate production depicts fed-state adaptation to protein restriction in humans.

  American journal of physiology. Endocrinology and metabolism 20010801

• Effect of protein restriction on (15)N transfer from dietary [(15)N]alanine and [(15)N]Spirulina platensis into urea.

  American journal of physiology. Endocrinology and metabolism 20010801

• Rebamipide inhibits ceramide-induced interleukin-8 production in Kato III human gastric cancer cells.

  The Journal of pharmacology and experimental therapeutics 20010801

• Open channel block of HERG K(+) channels by vesnarinone.

  Molecular pharmacology 20010801

• Kinetic analysis of the interactions of complement receptor 2 (CR2, CD21) with its ligands C3d, iC3b, and the EBV glycoprotein gp350/220.

  Journal of immunology (Baltimore, Md. : 1950) 20010801

• Microbial degradation of mefenoxam in rhizosphere of Zinnia angustifolia.

  Chemosphere 20010801

• Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis.

  The EMBO journal 20010801

• Identification of potential substrate-binding sites in yeast and human acyl-CoA sterol acyltransferases by mutagenesis of conserved sequences.

  Journal of lipid research 20010801

• Increased islet DNA synthesis and glucose-derived lipid and amino acid production in association with beta-cell hyperproliferation in normoglycaemic 60 % pancreatectomy rats.

  Diabetologia 20010801

• Regional localization and developmental profile of acetylcholinesterase-evoked increases in [(3)H]-5-fluororwillardiine binding to AMPA receptors in rat brain.

  British journal of pharmacology 20010801

• Neural-network analysis of the vibrational spectra of N-acetyl L-alanyl N'-methyl amide conformational states.

  Physical review. E, Statistical, nonlinear, and soft matter physics 20010801

• Sexual dimorphism in counterregulatory responses to hypoglycemia after antecedent exercise.

  The Journal of clinical endocrinology and metabolism 20010801

• Thermodynamic quantitative structure-activity relationship analysis for enzyme-ligand interactions in aqueous phosphate buffer and organic solvent.

  Bioorganic & medicinal chemistry 20010801

• Changes in mate recognition through alterations of pheromones and receptors in the multisexual mushroom fungus Schizophyllum commune.

  Genetics 20010801

• Metabolic and hormonal effects of tacrolimus (FK506) or cyclosporin immunosuppression following renal transplantation.

  Diabetes, obesity & metabolism 20010801

• Identification and characterization by high-performance liquid chromatography/electrospray ionization mass spectrometry of a new variant hemoglobin, Mataro [beta134(H12) Val > Ala.

  Journal of mass spectrometry : JMS 20010801

• Novel cyclic peptide inhibits intercellular adhesion molecule-1-mediated cell aggregation.

  The journal of peptide research : official journal of the American Peptide Society 20010801

• Determination of free intracellular amino acids in single mouse peritoneal macrophages after naphthalene-2,3-dicarboxaldehyde derivatization by capillary zone electrophoresis with electrochemical detection.

  Electrophoresis 20010801

• Utilization of a receptor reserve for effective amplification of mitogenic signaling by an epidermal growth factor mutant deficient in receptor activation.

  Journal of cellular biochemistry 20010801

• Preparation of and tissue response to DNA-lipid films.

  Journal of dental research 20010801

• Metabolic responses of the limpet Patella caerulea (L.) to anoxia and dehydration.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20010801

• Myosin II heavy chain isoforms are phosphorylated in an EGF-dependent manner: involvement of protein kinase C.

  Journal of cell science 20010801

• Effects of the antidepressant/antipanic drug phenelzine on alanine and alanine transaminase in rat brain.

  Cellular and molecular neurobiology 20010801

• Synergistic interactions of multiple mutations on catalysis during the hydroxylation reaction of p-hydroxybenzoate hydroxylase: studies of the Lys297Met, Asn300Asp, and Tyr385Phe mutants reconstituted with 8-Cl-flavin.

  Biochemistry 20010731

• Membrane interactions of mutated forms of the influenza fusion peptide.

  Biochemistry 20010731

• The chaperone protein 14-3-3eta interacts with the nicotinic acetylcholine receptor alpha 4 subunit. Evidence for a dynamic role in subunit stabilization.

  The Journal of biological chemistry 20010727

• Molecular basis for the constitutive activity of estrogen-related receptor alpha-1.

  The Journal of biological chemistry 20010727

• A discontinuous SNAP-25 C-terminal coil supports exocytosis.

  The Journal of biological chemistry 20010727

• The length, phosphorylation state, and primary structure of the RNA polymerase II carboxyl-terminal domain dictate interactions with mRNA capping enzymes.

  The Journal of biological chemistry 20010727

• Turn structures in CGRP C-terminal analogues promote stable arrangements of key residue side chains.

  Biochemistry 20010727

• beta -Helical polymers from isocyanopeptides.

  Science (New York, N.Y.) 20010727

• The neuroprotective activity of 8-alkylamino-1,4-benzoxazine antioxidants.

  European journal of pharmacology 20010727

• Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.

  Biochemistry 20010724

• Inactivation of C30A trimethylamine dehydrogenase by N-cyclopropyl-alpha-methylbenzylamine, 1-phenylcyclopropylamine, and phenylhydrazine.

  Biochemistry 20010724

• Effect of mutation of proline 93 on redox unfolding/folding of bovine pancreatic ribonuclease A.

  Biochemistry 20010724

• Site-directed mutation of the highly conserved region near the Q-loop of the cytochrome bd quinol oxidase from Escherichia coli specifically perturbs heme b595.

  Biochemistry 20010724

• Structure of Ala(20) --> Pro/Pro(64) --> Ala substituted subunit c of Escherichia coli ATP synthase in which the essential proline is switched between transmembrane helices.

  The Journal of biological chemistry 20010720

• Domain structure and mutational analysis of T4 polynucleotide kinase.

  The Journal of biological chemistry 20010720

• Anticonvulsant activity of a mGlu(4alpha) receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid.

  European journal of pharmacology 20010720

• A conservative amino acid substitution alters the regiospecificity of CYP94A2, a fatty acid hydroxylase from the plant Vicia sativa.

  Archives of biochemistry and biophysics 20010715

• High glycolytic activity in rat glioma demonstrated in vivo by correlation peak 1H magnetic resonance imaging.

  Cancer research 20010715

• Sites on FIP-3 (NEMO/IKKgamma) essential for its phosphorylation and NF-kappaB modulating activity.

  Biochemical and biophysical research communications 20010713

• Inhibition of AmpC beta-lactamase through a destabilizing interaction in the active site.

  Biochemistry 20010710

• Substitution of Thr for Ala-237 in TEM-17, TEM-12 and TEM-26: alterations in beta-lactam resistance conferred on Escherichia coli.

  FEMS microbiology letters 20010710

• Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains.

  Nature 20010705

• The predicted ATP-binding domains in the hexose transporter GLUT1 critically affect transporter activity.

  Biochemistry 20010703

• Dosimetry of blood irradiation using an alanine/ESR dosimeter.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20010701

• Mutagenesis of the dengue virus type 2 NS3 proteinase and the production of growth-restricted virus.

  The Journal of general virology 20010701

• Positional importance of Pro53 adjacent to the Arg49-Gly50-Asp51 sequence of rhodostomin in binding to integrin alphaIIbbeta3.

  The Biochemical journal 20010701

• Boronated dipeptide borotrimethylglycylphenylalanine as a potential boron carrier in boron neutron capture therapy for malignant brain tumors.

  Radiation research 20010701

• T cell epitope mapping of the Smith antigen reveals that highly conserved Smith antigen motifs are the dominant target of T cell immunity in systemic lupus erythematosus.

  Journal of immunology (Baltimore, Md. : 1950) 20010701

• Proteins with beta-(thienopyrrolyl)alanines as alternative chromophores and pharmaceutically active amino acids.

  Protein science : a publication of the Protein Society 20010701

• Regio-selective detection of dynamic structure of transmembrane alpha-helices as revealed from (13)C NMR spectra of [3-13C]Ala-labeled bacteriorhodopsin in the presence of Mn2+ ion.

  Biophysical journal 20010701

• Association of the Ala54-Thr polymorphism in the intestinal fatty acid-binding protein with 2-h postchallenge insulin levels in the Framingham Offspring Study.

  Diabetes care 20010701

• Mutation of cysteine-295 to alanine in secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus affects the enantioselectivity and substrate specificity of ketone reductions.

  Bioorganic & medicinal chemistry 20010701

• Characterization of Na+-coupled glutamate/aspartate transport by a rat brain astrocyte line expressing GLAST and EAAC1.

  The Journal of membrane biology 20010701

• Structural determinants of CCR5 recognition and HIV-1 blockade in RANTES.

  Nature structural biology 20010701

• Strong hydrogen-bonded amino acid dimers in L-alanine alaninium nitrate.

  Acta crystallographica. Section C, Crystal structure communications 20010701

• Effects of cod bradykinin and its analogs on vascular and intestinal smooth muscle of the Atlantic cod, Gadus morhua.

  Peptides 20010701

• MALDI-PSD-MS analysis of the phosphorylation sites of caseinomacropeptide.

  Peptides 20010701

• Evolution of the insulin molecule: insights into structure-activity and phylogenetic relationships.

  Peptides 20010701

• The conserved Asn49 of maize glutathione S-transferase I modulates substrate binding, catalysis and intersubunit communication.

  European journal of biochemistry 20010701

• Synthesis, X-ray crystallographic structures of thio substituted N-acetyl N'-methylamide alanine and evaluation of sp sulfur parameters of the CFF91 force field.

  The journal of peptide research : official journal of the American Peptide Society 20010701

• Conformational dynamics of an alanine dipeptide analog: an ab initio molecular dynamics study.

  Physical review. E, Statistical, nonlinear, and soft matter physics 20010701

• Alterations of epithelial permeability by Helicobacter and IL-1beta in vitro: protective effect of rebamipide.

  Digestive diseases and sciences 20010701

• Dosimetry of beta-ray ophthalmic applicators: comparison of different measurement methods.

  Medical physics 20010701

• Effect of the Pro12Ala polymorphism of the PPAR-gamma2 gene on long-term weight change in Finnish non-diabetic subjects.

  Diabetologia 20010701

• Structural heterogeneity of blue copper proteins: an EPR study of amicyanin and of wild-type and Cys3Ala/Cys26Ala mutant azurin.

  European biophysics journal : EBJ 20010701

• [The frequencies of the low-molecular-weight alanine-rich cold shock proteins genes and variation of their primary structure in plants of temperate climate].

  Genetika 20010701

• The anomalous infrared amide I intensity distribution in (13)C isotopically labeled peptide beta-sheets comes from extended, multiple-stranded structures: an ab initio study.

  Journal of the American Chemical Society 20010627

• Catalytic acid-base groups in yeast pyruvate decarboxylase. 1. Site-directed mutagenesis and steady-state kinetic studies on the enzyme with the D28A, H114F, H115F, and E477Q substitutions.

  Biochemistry 20010626

• Catalytic acid-base groups in yeast pyruvate decarboxylase. 2. Insights into the specific roles of D28 and E477 from the rates and stereospecificity of formation of carboligase side products.

  Biochemistry 20010626

• Catalytic acid-base groups in yeast pyruvate decarboxylase. 3. A steady-state kinetic model consistent with the behavior of both wild-type and variant enzymes at all relevant pH values.

  Biochemistry 20010626

• Influence of the aglycone region of the substrate binding cleft of Pseudomonas xylanase 10A on catalysis.

  Biochemistry 20010626

• Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity.

  Biochemistry 20010626

• Nuclear extracellular signal-regulated kinase 2 phosphorylates p53 at Thr55 in response to doxorubicin.

  Biochemical and biophysical research communications 20010622

• Requirements of basic amino acid residues within the lectin-like domain of LOX-1 for the binding of oxidized low-density lipoprotein.

  FEBS letters 20010622

• [An uncommon cause of severe soft tissue bleeding during phenprocoumon treatment].

  Deutsche medizinische Wochenschrift (1946) 20010622

• Helix unfolding in unsolvated peptides.

  Journal of the American Chemical Society 20010620

• Improved resolution in proton NMR spectroscopy of powdered solids.

  Journal of the American Chemical Society 20010620

• Long-distance movement and replication maintenance functions correlate with silencing suppression activity of potyviral HC-Pro.

  Virology 20010620

• An essential residue in the flexible peptide linking the two idiosynchratic domains of bacterial tyrosyl-tRNA synthetases.

  Biochemistry 20010619

• Engineering a functional blue-wavelength-shifted rhodopsin mutant.

  Biochemistry 20010619

• The A245K mutation exposes another stage of the bacterial L-lactate dehydrogenase reaction mechanism.

  Biochemistry 20010619

• Role of phylogenetically conserved amino acids in folding of Na,K-ATPase.

  Biochemistry 20010619

• The active N-terminal region of p67phox. Structure at 1.8 A resolution and biochemical characterizations of the A128V mutant implicated in chronic granulomatous disease.

  The Journal of biological chemistry 20010615

• Partial reconstitution of photoreceptor cGMP phosphodiesterase characteristics in cGMP phosphodiesterase-5.

  The Journal of biological chemistry 20010615

• Evidence for direct interaction between enzyme I(Ntr) and aspartokinase to regulate bacterial oligopeptide transport.

  The Journal of biological chemistry 20010615

• Incorporation of beta-selenolo[3,2-b]pyrrolyl-alanine into proteins for phase determination in protein X-ray crystallography.

  Journal of molecular biology 20010615

• A novel human amino acid transporter, hNAT3: cDNA cloning, chromosomal mapping, genomic structure, expression, and functional characterization.

  Genomics 20010615

• cis-Inhibition of proteasomal degradation by viral repeats: impact of length and amino acid composition.

  FEBS letters 20010615

• Synthesis and structure determination of some sugar amino acids related to alanine and 6-deoxymannojirimycin.

  Carbohydrate research 20010615

• ATP-dependent activation of the intermediate conductance, Ca2+-activated K+ channel, hIK1, is conferred by a C-terminal domain.

  The Journal of biological chemistry 20010615

• The YXXQ motif in gp 130 is crucial for STAT3 phosphorylation at Ser727 through an H7-sensitive kinase pathway.

  Oncogene 20010614

• Acid-base catalysis by UDP-galactose 4-epimerase: correlations of kinetically measured acid dissociation constants with thermodynamic values for tyrosine 149.

  Biochemistry 20010605

• Determination of free D-aspartic acid, D-serine and D-alanine in the brain of mutant mice lacking D-amino acid oxidase activity.

  Journal of chromatography. B, Biomedical sciences and applications 20010605

• Infection by Trypanosoma cruzi. Identification of a parasite ligand and its host cell receptor.

  The Journal of biological chemistry 20010601

• Effects of antecedent prolonged exercise on subsequent counterregulatory responses to hypoglycemia.

  American journal of physiology. Endocrinology and metabolism 20010601

• Internalisation of the protease-activated receptor 1: role of the third intracellular loop and of the cytoplasmic tail.

  International journal of molecular medicine 20010601

• C-peptide binding to human cell membranes: importance of Glu27.

  Biochemical and biophysical research communications 20010601

• Rat liver responsiveness to gluconeogenic substrates during insulin-induced hypoglycemia.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010601

• Interplant alkaloid variation and Senecio vernalis toxicity in cattle.

  Veterinary and human toxicology 20010601

• Inherited prion disease with A117V mutation of the prion protein gene: a novel Hungarian family.

  Journal of neurology, neurosurgery, and psychiatry 20010601

• Effect of dopexamine on hepatic metabolic activity in patients with septic shock.

  Shock (Augusta, Ga.) 20010601

• Functional consequences of the autosomal dominant G272A mutation in the human GLUT1 gene.

  FEBS letters 20010601

• Mutational analysis of the IgE epitopes in the latex allergen Hev b 5.

  The Journal of allergy and clinical immunology 20010601

• Acute effect of the dual angiotensin-converting enzyme and neutral endopeptidase 24-11 inhibitor mixanpril on insulin sensitivity in obese Zucker rat.

  British journal of pharmacology 20010601

• Optimized aminolysis conditions for cleavage of N-protected hydrophobic peptides from solid-phase resins.

  The journal of peptide research : official journal of the American Peptide Society 20010601

• Studies on analogs of a peptide derived from alpha-fetoprotein having antigrowth properties.

  The journal of peptide research : official journal of the American Peptide Society 20010601

• Mutagenesis of beta-tubulin cysteine residues in Saccharomyces cerevisiae: mutation of cysteine 354 results in cold-stable microtubules.

  Cell motility and the cytoskeleton 20010601

• Idiopathic hemochromatosis with the mutation of Ala176Val heterozygous for HFE gene.

  Internal medicine (Tokyo, Japan) 20010601

• Combinatorial alanine-scanning.

  Current opinion in chemical biology 20010601

• High-resolution magic angle spinning 1H-NMR spectroscopy studies on the renal biochemistry in the bank vole (Clethrionomys glareolus) and the effects of arsenic (As3+) toxicity.

  Xenobiotica; the fate of foreign compounds in biological systems 20010601

• Safinamide (Newron Pharmaceuticals).

  Current opinion in investigational drugs (London, England : 2000) 20010601

• Neurotoxic effect of high dose of L-(+)-2-amino-3-phosphonopropionic acid in rats after intracaudatal injection.

  Acta pharmacologica Sinica 20010601

• Role of enzyme-ribofuranosyl contacts in the ground state and transition state for orotidine 5'-phosphate decarboxylase: a role for substrate destabilization?

  Biochemistry 20010529

• High-level bacterial expression and 15N-alanine-labeling of bovine trypsin. Application to the study of trypsin-inhibitor complexes and trypsinogen activation by NMR spectroscopy.

  Biochemistry 20010529

• Insight into the mechanism of serpin-proteinase inhibition from 2D [1H-15N] NMR studies of the 69 kDa alpha 1-proteinase inhibitor Pittsburgh-trypsin covalent complex.

  Biochemistry 20010529

• Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease.

  Biochemistry 20010529

• Membrane activity of the peptide antibiotic clavanin and the importance of its glycine residues.

  Biochemistry 20010529

• Alanine-scanning mutagenesis of plasmatocyte spreading peptide identifies critical residues for biological activity.

  The Journal of biological chemistry 20010525

• Characterization and manipulation of the acyl chain selectivity of fatty acid amide hydrolase.

  Biochemistry 20010522

• Familial parkinsonism with synuclein pathology: clinical and PET studies of A30P mutation carriers.

  Neurology 20010522

• Phospho-Azatyrosine, a less effective protein-tyrosine phosphatase substrate than phosphotyrosine.

  Bioorganic & medicinal chemistry letters 20010521

• Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.

  The Journal of biological chemistry 20010518

• Determination of the functional epitopes of human interleukin-18-binding protein by site-directed mutagenesis.

  The Journal of biological chemistry 20010518

• Unusually stable and long-lived ligand-induced conformations of integrins.

  The Journal of biological chemistry 20010518

• Identification of critical residues in bovine IFNAR-1 responsible for interferon binding.

  The Journal of biological chemistry 20010518

• Identification of thermodynamically relevant interactions between EF-Tu and backbone elements of tRNA.

  Journal of molecular biology 20010518

• [Polymorphism of pro12Ala in peroxisome proliferator activated receptor gamma 2 (PPAgamma2): beta cell function and insulin sensitivity].

  Deutsche medizinische Wochenschrift (1946) 20010518

• Solid phase synthesis of carbocyclic l-2'-deoxynucleosides.

  Organic letters 20010517

• Isolation, structure determination, and synthesis of neodysiherbaine A, a new excitatory amino acid from a marine sponge.

  Organic letters 20010517

• Substitution of murine ferrochelatase glutamate-287 with glutamine or alanine leads to porphyrin substrate-bound variants.

  The Biochemical journal 20010515

• Design of Gram-negative selective antimicrobial peptides.

  Biochemistry 20010515

• Developmental and cell-cycle regulation of Caenorhabditis elegans HCF phosphorylation.

  Biochemistry 20010515

• Cutting edge: a single MHC anchor residue alters the conformation of a peptide-MHC complex inducing T cells that survive negative selection.

  Journal of immunology (Baltimore, Md. : 1950) 20010515

• Selective neurotensin-derived internally quenched fluorogenic substrates for neurolysin (EC 3.4.24.16): comparison with thimet oligopeptidase (EC 3.4.24.15) and neprilysin (EC 3.4.24.11).

  Analytical biochemistry 20010515

• Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters.

  European journal of pharmacology 20010511

• Kinetic analysis of three activated phenylalanyl intermediates generated by the initiation module PheATE of gramicidin S synthetase.

  Biochemistry 20010508

• Organization of the multiple coenzymes and subunits and role of the covalent flavin link in the complex heterotetrameric sarcosine oxidase.

  Biochemistry 20010508

• A conserved threonine within Escherichia coli leucyl-tRNA synthetase prevents hydrolytic editing of leucyl-tRNALeu.

  Biochemistry 20010508

• Signal transduction by the CEACAM1 tumor suppressor. Phosphorylation of serine 503 is required for growth-inhibitory activity.

  The Journal of biological chemistry 20010504

• Na+-alanine uptake activates a Cl- conductance in frog renal proximal tubule cells via nonconventional PKC.

  American journal of physiology. Renal physiology 20010501

• Orbofiban: an orally active GPIIb/IIIa platelet receptor antagonist.

  Medicinal research reviews 20010501

• Phosphate-binding loop and Rab GTPase function: mutations at Ser29 and Ala30 of Rab5 lead to loss-of-function as well as gain-of-function phenotype.

  The Biochemical journal 20010501

• In vitro studies of amyloid beta-protein fibril assembly and toxicity provide clues to the aetiology of Flemish variant (Ala692-->Gly) Alzheimer's disease.

  The Biochemical journal 20010501

• Homozygosity for alanine in the mitochondrial targeting sequence of superoxide dismutase and risk for severe alcoholic liver disease.

  Gastroenterology 20010501

• Parameters affecting the restoration of activity to inactive mutants of thymidylate synthase via subunit exchange: further evidence that thymidylate synthase is a half-of-the-sites activity enzyme.

  Biochemistry 20010501

• How Ala-->Gly mutations in different helices affect the stability of the apomyoglobin molten globule.

  Biochemistry 20010501

• Yersiniabactin synthetase: probing the recognition of carrier protein domains by the catalytic heterocyclization domains, Cy1 and Cy2, in the chain-initiating HWMP2 subunit.

  Biochemistry 20010501

• Protein crystallization by rational mutagenesis of surface residues: Lys to Ala mutations promote crystallization of RhoGDI.

  Acta crystallographica. Section D, Biological crystallography 20010501

• Mechanism underlying slow kinetics of the OFF gating current in Shaker potassium channel.

  Biophysical journal 20010501

• 13C isotopomer analysis of glucose and alanine metabolism reveals cytosolic pyruvate compartmentation as part of energy metabolism in astrocytes.

  Glia 20010501

• Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator--activated receptor-gamma2 gene.

  Diabetes 20010501

• Proton MR spectroscopy with metabolite-nulling reveals elevated macromolecules in acute multiple sclerosis.

  Brain : a journal of neurology 20010501

• Lantibiotics: structure, biosynthesis and mode of action.

  FEMS microbiology reviews 20010501

• Identification of residues critical for enzymatic activity in the domain encoded by exons 8 and 9 of the human inducible nitric oxide synthase.

  American journal of respiratory cell and molecular biology 20010501

• DL-Alanine.

  Acta crystallographica. Section C, Crystal structure communications 20010501

• Biochemical characterization and identification of catalytic residues in alpha-glucuronidase from Bacillus stearothermophilus T-6.

  European journal of biochemistry 20010501

• [Biosynthesis of nonessential amino acids and the urea-cycle in silkworms].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20010501

• Persistence, fate, and metabolism of [(14)C]metalaxyl in typical Indian soils.

  Journal of agricultural and food chemistry 20010501

• Significance of soil properties in the adsorption and mobility of the fungicide metalaxyl in vineyard soils.

  Journal of agricultural and food chemistry 20010501

• Ethanol and protein metabolism.

  Alcoholism, clinical and experimental research 20010501

• Rebamipide prevents periarterial blood-induced vasospasm in the rat femoral artery model.

  Pharmacological research 20010501

• Reduction in the rates of protein and amino acid catabolism to slow down the accumulation of endogenous ammonia: a strategy potentially adopted by mudskippers (Periophthalmodon schlosseri snd Boleophthalmus boddaerti) during aerial exposure in constant darkness.

  The Journal of experimental biology 20010501

• Partial amino acid catabolism leading to the formation of alanine in Periophthalmodon schlosseri (mudskipper): a strategy that facilitates the use of amino acids as an energy source during locomotory activity on land.

  The Journal of experimental biology 20010501

• An intrahelical salt bridge within the trigger site stabilizes the GCN4 leucine zipper.

  The Journal of biological chemistry 20010427

• Structure-activity relationship studies of melanin-concentrating hormone (MCH)-related peptide ligands at SLC-1, the human MCH receptor.

  The Journal of biological chemistry 20010427

• Delta 3,5,delta 2,4-dienoyl-CoA isomerase is a multifunctional isomerase. A structural and mechanistic study.

  The Journal of biological chemistry 20010427

• Identification of receptor binding and activation determinants in the N-terminal and N-loop regions of the CC chemokine eotaxin.

  The Journal of biological chemistry 20010427

• Contribution of the active site histidine residues of ribonuclease A to nucleic acid binding.

  Biochemistry 20010424

• Sensitivity of single membrane-spanning alpha-helical peptides to hydrophobic mismatch with a lipid bilayer: effects on backbone structure, orientation, and extent of membrane incorporation.

  Biochemistry 20010424

• Interaction of apo-cytochrome b5 with cytochromes P4503A4 and P45017A: relevance of heme transfer reactions.

  Biochemistry 20010424

• Synthesis and evaluation of novel amidate prodrugs of PMEA and PMPA.

  Bioorganic & medicinal chemistry letters 20010423

• Phosphorylation of Ser363, Thr370, and Ser375 residues within the carboxyl tail differentially regulates mu-opioid receptor internalization.

  The Journal of biological chemistry 20010420

• Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4.

  The Journal of biological chemistry 20010420

• Colipase residues Glu64 and Arg65 are essential for normal lipase-mediated fat digestion in the presence of bile salt micelles.

  The Journal of biological chemistry 20010420

• Mechanism of dihydropyridine interaction with critical binding residues of L-type Ca2+ channel alpha 1 subunits.

  The Journal of biological chemistry 20010420

• Convergent synthesis of peptide conjugates using dehydroalanines for chemoselective ligations.

  Organic letters 20010419

• Probing the active site of L-aspartate oxidase by site-directed mutagenesis: role of basic residues in fumarate reduction.

  Biochemistry 20010417

• Structural and dynamic perturbations induced by heme binding in cytochrome b5.

  Biochemistry 20010417

• Recruitment of the transcriptional machinery through GAL11P: structure and interactions of the GAL4 dimerization domain.

  Genes & development 20010415

• Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo).

  European journal of pharmacology 20010413

• Oxidations of p-alkoxyacylanilides catalyzed by human cytochrome P450 1A2: structure-activity relationships and simulation of rate constants of individual steps in catalysis.

  Biochemistry 20010410

• A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor.

  The Journal of biological chemistry 20010406

• Mapping arm-DNA-binding domain interactions in AraC.

  Journal of molecular biology 20010406

• Inactivation of pyruvate formate-lyase by dioxygen: defining the mechanistic interplay of glycine 734 and cysteine 419 by rapid freeze-quench EPR.

  Biochemistry 20010403

• Persistent binding of MgADP to the E187A mutant of Escherichia coli phosphofructokinase in the absence of allosteric effects.

  Biochemistry 20010403

• MgATP-dependent activation by phosphoenolpyruvate of the E187A mutant of Escherichia coli phosphofructokinase.

  Biochemistry 20010403

• Phosphorylation mutants elucidate the mechanism of annexin IV-mediated membrane aggregation.

  Biochemistry 20010403

• Production and specificity of mono and polyclonal antibodies against microcystins conjugated through N-methyldehydroalanine.

  Toxicon : official journal of the International Society on Toxinology 20010401

• Transport of exogenous organic substances by invertebrate integuments: the field revisited.

  The Journal of experimental zoology 20010401

• Cysteinylation of MHC class II ligands: peptide endocytosis and reduction within APC influences T cell recognition.

  Journal of immunology (Baltimore, Md. : 1950) 20010401

• Rebamipide suppresses formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide production by inhibiting fMLP-receptor binding in human neutrophils.

  The Journal of pharmacology and experimental therapeutics 20010401

• Sequencing of the ddl gene and modeling of the mutated D-alanine:D-alanine ligase in glycopeptide-dependent strains of Enterococcus faecium.

  Protein science : a publication of the Protein Society 20010401

• Holoprosencephaly due to mutations in ZIC2: alanine tract expansion mutations may be caused by parental somatic recombination.

  Human molecular genetics 20010401

• A potential phosphorylation site for an A-type kinase in the Efg1 regulator protein contributes to hyphal morphogenesis of Candida albicans.

  Genetics 20010401

• Carbohydrate depletion has profound effects on the muscle amino acid and glucose metabolism during hyperinsulinaemia.

  Diabetes, obesity & metabolism 20010401

• Identification of catalytically important residues in the active site of Escherichia coli transaldolase.

  European journal of biochemistry 20010401

• The association between the val/ala-55 polymorphism of the uncoupling protein 2 gene and exercise efficiency.

  International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20010401

• Synthesis and biochemical evaluation of some novel N-acyl phosphono- and phosphinoalanine derivatives as potential inhibitors of the D-glutamic acid-adding enzyme.

  Die Pharmazie 20010401

• Thermodynamic aspects of hydrophobicity and biological QSAR.

  Journal of computer-aided molecular design 20010401

• Purification and characterization of N-glycosylation mutant mouse and human P-glycoproteins expressed in Pichia pastoris cells.

  Archives of biochemistry and biophysics 20010401

• Improving the selectivity of HAV-peptides in modulating E-cadherin-E-cadherin interactions in the intercellular junction of MDCK cell monolayers.

  Pharmaceutical research 20010401

• Metalaxyl effect on nitrogenase activity (acetylene reduction) and yield of mungbean (Vigna radiata (L.) wilzek).

  Journal of environmental biology 20010401

• Boron neutron capture therapy: effects of split dose and overall treatment time.

  Journal of neuro-oncology 20010401

• Protein glycation: creation of catalytic sites for free radical generation.

  Annals of the New York Academy of Sciences 20010401

• Fluorescence enhancement of coumarin-6-sulfonyl chloride amino acid derivatives in cyclodextrin media.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010401

• Identification of the collagen-binding site of the von Willebrand factor A3-domain.

  The Journal of biological chemistry 20010330

• Role of two histidines in the (6-4) photolyase reaction.

  The Journal of biological chemistry 20010330

• Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism.

  The Journal of biological chemistry 20010330

• Construction of a high affinity zinc binding site in the metabotropic glutamate receptor mGluR1: noncompetitive antagonism originating from the amino-terminal domain of a family C G-protein-coupled receptor.

  The Journal of biological chemistry 20010330

• Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69.

  The Journal of biological chemistry 20010330

• Alternative O-glycosylation/O-phosphorylation of serine-16 in murine estrogen receptor beta: post-translational regulation of turnover and transactivation activity.

  The Journal of biological chemistry 20010330

• Investigation of allosteric linkages in the regulation of tryptophan synthase: the roles of salt bridges and monovalent cations probed by site-directed mutation, optical spectroscopy, and kinetics.

  Biochemistry 20010327

• Titration of tertiapin-Q inhibition of ROMK1 channels by extracellular protons.

  Biochemistry 20010327

• Design and characterization of asparagine- and lysine-containing alanine-based helical peptides that bind selectively to A.T base pairs of oligonucleotides immobilized on a 27 mhz quartz crystal microbalance.

  Biochemistry 20010327

• Mutational analysis of chicken interleukin 2.

  Cytokine 20010321

• Stimulation of topoisomerase II-mediated DNA damage via a mechanism involving protein thiolation.

  Biochemistry 20010320

• Enantiospecific synthesis and pharmacological evaluation of a series of super-potent, conformationally restricted 5-HT(2A/2C) receptor agonists.

  Journal of medicinal chemistry 20010315

• A helical turn motif in Mss4 is a critical determinant of Rab binding and nucleotide release.

  Biochemistry 20010313

• Human flap endonuclease-1: conformational change upon binding to the flap DNA substrate and location of the Mg2+ binding site.

  Biochemistry 20010313

• The basis of prostaglandin synthesis in coral: molecular cloning and expression of a cyclooxygenase from the Arctic soft coral Gersemia fruticosa.

  The Journal of biological chemistry 20010309

• Zinc release from the CH2C6 zinc finger domain of FILAMENTOUS FLOWER protein from Arabidopsis thaliana induces self-assembly.

  The Journal of biological chemistry 20010309

• Redox properties and coordination structure of the heme in the co-sensing transcriptional activator CooA.

  The Journal of biological chemistry 20010309

• Sequence requirements for the N-methyl-D-aspartate receptor antagonist activity of conantokin-R.

  The Journal of biological chemistry 20010309

• Mutagenic analysis of functional residues in putative substrate-binding site and acidic domains of vacuolar H+-pyrophosphatase.

  The Journal of biological chemistry 20010309

• Regulation of ROMK1 channels by protein-tyrosine kinase and -tyrosine phosphatase.

  The Journal of biological chemistry 20010309

• Differential lipid specificities of the repeated domains of annexin IV.

  Biochimica et biophysica acta 20010309

• An improved synthesis of chiral alpha-(4-bromobenzyl)alanine ethyl ester and its application to the synthesis of LFA-1 antagonist BIRT-377.

  The Journal of organic chemistry 20010309

• Convenient synthesis and diversification of dehydroalaninyl phosphinic peptide analogues.

  Organic letters 20010308

• Direct comparison of experimental and calculated folding free energies for hydrophobic deletion mutants of chymotrypsin inhibitor 2: free energy perturbation calculations using transition and denatured states from molecular dynamics simulations of unfolding.

  Biochemistry 20010306

• The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.

  Biochemistry 20010306

• Interactions of the XylS regulators with the C-terminal domain of the RNA polymerase alpha subunit influence the expression level from the cognate Pm promoter.

  FEBS letters 20010302

• Hydrophobic analogues of the winter flounder 'antifreeze' protein.

  FEBS letters 20010302

• Influence of lysine content and pH on the stability of alanine-based copolypeptides.

  Biopolymers 20010301

• Electrogenic Na(+)-dependent L-alanine transport in the lizard duodenum. Involvement of systems A and ASC.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010301

• Potent cytolytic response by a CD8+ CTL clone to multiple peptides from the same protein in association with an allogeneic class I MHC molecule.

  Journal of immunology (Baltimore, Md. : 1950) 20010301

• Ligand migration in human myoglobin: steric effects of isoleucine 107(G8) on O(2) and CO binding.

  Biophysical journal 20010301

• Three-dimensional structure of human follicle-stimulating hormone.

  Molecular endocrinology (Baltimore, Md.) 20010301

• Insertional mutagenesis of the arginine cage domain of the gonadotropin-releasing hormone receptor.

  Molecular endocrinology (Baltimore, Md.) 20010301

• Surface dynamics of bacteriorhodopsin as revealed by (13)C NMR studies on [(13)C]Ala-labeled proteins: detection of millisecond or microsecond motions in interhelical loops and C-terminal alpha-helix.

  Journal of biochemistry 20010301

• Association of white blood cell count with increased mortality in acute myocardial infarction and unstable angina pectoris. OPUS-TIMI 16 Investigators.

  The American journal of cardiology 20010301

• Physico-chemical requirements for cellular uptake of pAntp peptide. Role of lipid-binding affinity.

  European journal of biochemistry 20010301

• A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidaemia in obesity.

  European journal of endocrinology 20010301

• Factors involved in the (near) anoxic survival time of Cerastoderma edule: associated bacteria vs. endogenous fuel.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010301

• Cucumber mosaic virus-plant interactions: identification of 3a protein sequences affecting infectivity, cell-to-cell movement, and long-distance movement.

  Molecular plant-microbe interactions : MPMI 20010301

• Different binding sites for the neuropeptide Y Y1 antagonists 1229U91 and J-104870 on human Y1 receptors.

  Peptides 20010301

• ASEdb: a database of alanine mutations and their effects on the free energy of binding in protein interactions.

  Bioinformatics (Oxford, England) 20010301

• Synthesis of tetrapeptide p-nitrophenylanilides containing dehydroalanine and dehydrophenylalanine and their influence on cathepsin C activity.

  Journal of peptide science : an official publication of the European Peptide Society 20010301

• Structural adaptation of enzymes to low temperatures.

  Protein engineering 20010301

• Site-specific cation binding mediates TATA binding protein-DNA interaction from a hyperthermophilic archaeon.

  Biochemistry 20010227

• Occurrence of D-Amino Acids and a pyridoxal 5'-phosphate-dependent aspartate racemase in the acidothermophilic archaeon, Thermoplasma acidophilum.

  Biochemical and biophysical research communications 20010223

• Role of Thr(11) in the binding of omega-conotoxin MVIIC to N-type Ca2+ channels.

  FEBS letters 20010223

• Synthesis of 2-amino-3-fluoroacrylic acid containing peptides.

  Organic letters 20010222

• The structural basis for the perturbed pKa of the catalytic base in 4-oxalocrotonate tautomerase: kinetic and structural effects of mutations of Phe-50.

  Biochemistry 20010220

• Trp 346 and Leu 352 residues in protective antigen are required for the expression of anthrax lethal toxin activity.

  Biochemical and biophysical research communications 20010216

• A repeated beta-turn structure in poly(Ala-Gly) as a model for silk I of Bombyx mori silk fibroin studied with two-dimensional spin-diffusion NMR under off magic angle spinning and rotational echo double resonance.

  Journal of molecular biology 20010216

• The A' and F' pockets of human CD1b are both required for optimal presentation of lipid antigens to T cells.

  Journal of immunology (Baltimore, Md. : 1950) 20010215

• Crystal structures and iron release properties of mutants (K206A and K296A) that abolish the dilysine interaction in the N-lobe of human transferrin.

  Biochemistry 20010213

• Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II.

  Biochemistry 20010213

• Consequences of a modified putative substrate-activation site on catalysis by yeast pyruvate decarboxylase.

  Biochemistry 20010213

• Synthesis and biological activity of novel potent endothelin-converting enzyme-1 inhibitors.

  Bioorganic & medicinal chemistry letters 20010212

• The role of a proline-induced broken-helix motif in alpha-helix 2 of Bacillus thuringiensis delta-endotoxins.

  FEBS letters 20010209

• Asymmetric synthesis of alpha,beta-dialkyl-alpha-phenylalanines via direct alkylation of a chiral alanine derivative with racemic alpha-alkylbenzyl bromides. A case of high enantiomer differentiation at room temperature.

  Organic letters 20010208

• Effect of alanine-293 replacement on the activity, ATP binding, and editing of Escherichia coli leucyl-tRNA synthetase.

  Biochemistry 20010206

• Rapid kinetic and isotopic studies on dialkylglycine decarboxylase.

  Biochemistry 20010206

• Hormone interactions to Leu-rich repeats in the gonadotropin receptors. I. Analysis of Leu-rich repeats of human luteinizing hormone/chorionic gonadotropin receptor and follicle-stimulating hormone receptor.

  The Journal of biological chemistry 20010202

• DNA recognition by the methyl-CpG binding domain of MeCP2.

  The Journal of biological chemistry 20010202

• An activation switch in the ligand binding pocket of the C5a receptor.

  The Journal of biological chemistry 20010202

• Effect of the peroxisome proliferator-activated receptor-gamma 2 pro(12)ala variant on obesity, glucose homeostasis, and blood pressure in members of familial type 2 diabetic kindreds.

  The Journal of clinical endocrinology and metabolism 20010201

• Ischemic dysfunction in transgenic mice expressing troponin I lacking protein kinase C phosphorylation sites.

  American journal of physiology. Heart and circulatory physiology 20010201

• Pharmacological properties of the potent epileptogenic amino acid dysiherbaine, a novel glutamate receptor agonist isolated from the marine sponge Dysidea herbacea.

  The Journal of pharmacology and experimental therapeutics 20010201

• Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138.

  Virology 20010201

• Combination of continuous subcutaneous infusion of insulin and octreotide in Type 1 diabetic patients.

  Diabetes research and clinical practice 20010201

• OPC-compounds prevent oxidant-induced carbonylation and depolymerization of the F-actin cytoskeleton and intestinal barrier hyperpermeability.

  Free radical biology & medicine 20010201

• Assembly of cytochrome f into the cytochrome bf complex in isolated pea chloroplasts.

  European journal of biochemistry 20010201

• Critical role of glutamic acid 202 in the enzymatic activity of stromelysin-1 (MMP-3).

  European journal of biochemistry 20010201

• Extensive alanine scanning reveals protein-protein and protein-DNA interaction surfaces in the global regulator FlhD from Escherichia coli.

  Molecular microbiology 20010201

• The effect of amino acid spacers on the antigenicity of dimeric peptide--inducing cross-reacting antibodies to a cell surface protein antigen of Streptococcus mutans.

  Oral microbiology and immunology 20010201

• PEPT1-mediated uptake of dipeptides enhances the intestinal absorption of amino acids via transport system b(0,+).

  Journal of cellular physiology 20010201

• Design, X-ray crystallography, molecular modelling and thermal stability studies of mutant enzymes at site 172 of 3-isopropylmalate dehydrogenase from Thermus thermophilus.

  Acta crystallographica. Section D, Biological crystallography 20010201

• Epitope mapping for four monoclonal antibodies against human plasminogen activator inhibitor type-1: implications for antibody-mediated PAI-1-neutralization and vitronectin-binding.

  European journal of biochemistry 20010201

• Changing serine-485 to alanine in the opossum parathyroid hormone (PTH)/PTH-related peptide receptor enhances PTH stimulation of phospholipase C in a stably transfected human kidney cell line: a useful model for PTH-analog screening?

  Bone 20010201

• Real-time, two-dimensional visualization of ischaemia-induced glutamate release from hippocampal slices.

  The European journal of neuroscience 20010201

• Systemic prostaglandin E1 infusion and hepatic aminonitrogen to urea nitrogen conversion in patients with type 2 diabetes in poor metabolic control.

  Metabolism: clinical and experimental 20010201

• Parasitism enhances the induction of glucogenesis by the insect, Manduca sexta L.

  The international journal of biochemistry & cell biology 20010201

• Conformational preferences of heterochiral peptides. Crystal structures of heterochiral peptides Boc-(D) Val-(D) Ala-Leu-Ala-OMe and Boc-Val-Ala-Leu-(D) Ala-OMe--enhanced stability of beta-sheet through C-H...O hydrogen bonds.

  Journal of biomolecular structure & dynamics 20010201

• Interactions between mastoparan B and the membrane studied by 1H NMR spectroscopy.

  Journal of biomolecular structure & dynamics 20010201

• Alanine scan mutagenesis of the switch I domain of the Caulobacter crescentus CgtA protein reveals critical amino acids required for in vivo function.

  Molecular microbiology 20010201

• Alpha- and beta-cell responses to small changes in plasma glucose in the conscious dog.

  Diabetes 20010201

• Antibodies recognizing CD24 LAP epitope on human T cells enhance CD28 and IL-2 T cell proliferation.

  Journal of leukocyte biology 20010201

• Synthesis, conformational analysis and biological activities of lanthionine analogs of a cell adhesion modulator.

  Journal of peptide science : an official publication of the European Peptide Society 20010201

• Spatial heterogeneity of energy turnover in the heart.

  Pflugers Archiv : European journal of physiology 20010201

• Inhibitory effect of glycation on catalytic activity of alanine aminotransferase.

  Molecular and cellular biochemistry 20010201

• Coenzyme specificity of human monomeric carbonyl reductase: contribution of Lys-15, Ala-37 and Arg-38.

  Chemico-biological interactions 20010130

• The Arabidopsis thaliana isogene NIT4 and its orthologs in tobacco encode beta-cyano-L-alanine hydratase/nitrilase.

  The Journal of biological chemistry 20010126

• Interaction of quercetin glucosides with the intestinal sodium/glucose co-transporter (SGLT-1).

  Cancer letters 20010126

• Calcium inhibits willardiine-induced responses in kainate receptor GluR6(Q)/KA-2.

  Neuroreport 20010122

• The conserved domain CR2 of Epstein-Barr virus nuclear antigen leader protein is responsible not only for nuclear matrix association but also for nuclear localization.

  Virology 20010120

• HIV type 2 Vpx interaction with Gag and incorporation into virus-like particles.

  AIDS research and human retroviruses 20010120

• Follicle-stimulating-hormone receptor and twinning.

  Lancet (London, England) 20010120

• Metal ion inhibition of nonenzymatic pyridoxal phosphate catalyzed decarboxylation and transamination.

  Journal of the American Chemical Society 20010117

• Short, solubilized polyalanines are conformational chameleons: exceptionally helical if N- and C-capped with helix stabilizers, weakly to moderately helical if capped with rigid spacers.

  Biochemistry 20010116

• Substituting leucine for alanine-86 in the tether region of the iron-sulfur protein of the cytochrome bc1 complex affects the mobility of the [2Fe2S] domain.

  Biochemistry 20010116

• The PD...(D/E)XK motif in restriction enzymes: a link between function and conformation.

  Biochemistry 20010116

• Insights into the molecular basis for the carbenicillinase activity of PSE-4 beta-lactamase from crystallographic and kinetic studies.

  Biochemistry 20010116

• Chemical rescue of phosphoryl transfer in a cavity mutant: a cautionary tale for site-directed mutagenesis.

  Biochemistry 20010116

• Interactions between yeast iso-1-cytochrome c and its peroxidase.

  Biochemistry 20010116

• Effect of metal binding on electrogenic proton transfer associated with reduction of the secondary electron acceptor (QB) in Rhodobacter sphaeroides chromatophores.

  Biochemistry 20010116

• Peptide models of the helical hydrophobic transmembrane segments of membrane proteins: interactions of acetyl-K2-(LA)12-K2-amide with phosphatidylethanolamine bilayer membranes.

  Biochemistry 20010116

• Site-directed mutagenesis of the bacterial metalloamidase UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC). Identification of the zinc binding site.

  Biochemistry 20010116

• Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists: a meta-analysis of phase III multicenter randomized trials.

  Circulation 20010116

• Differential effects of the allosteric enhancer (2-amino-4,5-dimethyl-trienyl)[3-trifluoromethyl) phenyl]methanone (PD81,723) on agonist and antagonist binding and function at the human wild-type and a mutant (T277A) adenosine A1 receptor.

  Biochemical pharmacology 20010115

• Development and evaluation of a boronate inhibitor of gamma-glutamyl transpeptidase.

  Archives of biochemistry and biophysics 20010115

• Mechanism of action of a novel latent membrane protein-1 dominant negative.

  The Journal of biological chemistry 20010112

• Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis.

  Journal of molecular biology 20010112

• Stereochemistry and molecular pharmacology of (S)-thio-ATPA, a new potent and selective GluR5 agonist.

  European journal of pharmacology 20010112

• Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain.

  Neurochemistry international 20010101

• Structural and conformational properties of (Z)-beta-(1-naphthyl)- dehydroalanine residue.

  Biopolymers 20010101

• A (13)C NMR study on [3-(13)C]-, [1-(13)C]Ala-, or [1-(13)C]Val-labeled transmembrane peptides of bacteriorhodopsin in lipid bilayers: insertion, rigid-body motions, and local conformational fluctuations at ambient temperature.

  Biopolymers 20010101

• Helix nucleation kinetics from molecular simulations in explicit solvent.

  Proteins 20010101

• Characterization of the Co(2+) and Ni(2+) binding amino-acid residues of the N-terminus of human albumin. An insight into the mechanism of a new assay for myocardial ischemia.

  European journal of biochemistry 20010101

• Structure-activity relationships of neurokinin A (4-10) at the human tachykinin NK(2) receptor: the role of natural residues and their chirality.

  Biochemical pharmacology 20010101

• Is the Ala138Gly alteration of MEFV gene important for amyloidosis?

  Human mutation 20010101

• Novel mutations in the GALK1 gene in patients with galactokinase deficiency.

  Human mutation 20010101

• Low-dose IGF-I has no selective advantage over insulin in regulating glucose metabolism in hyperglycemic depancreatized dogs.

  The Journal of endocrinology 20010101

• Oral glycoprotein IIb/IIIa antagonists in coronary artery disease.

  Current cardiology reports 20010101

• Comparative antiplatelet efficacy of a novel, nonpeptide GPIIb/IIIa antagonist (XV454) and abciximab (c7E3) in flow models of thrombosis.

  Arteriosclerosis, thrombosis, and vascular biology 20010101

• Functional analysis of the putative peroxidase domain of FANCA, the Fanconi anemia complementation group A protein.

  Molecular genetics and metabolism 20010101

• The BCAA-BCKA cycle: its relation to alanine and glutamine synthesis and protein balance.

  Nutrition (Burbank, Los Angeles County, Calif.) 20010101

• Purification and some properties of alanine racemase from a bivalve mollusc Corbicula japonica.

  The Journal of experimental zoology 20010101

• Chloroplast genetic engineering.

  Trends in biotechnology 20010101

• EPR spectroscopic studies of the reduction of chromium(VI) by methanol in the presence of peptides. Formation of long-lived chromium(V) peptide complexes.

  Inorganic chemistry 20010101

• Interrelation between synthesis and uptake of ectoine for the growth of the halotolerant Brevibacterium species JCM 6894 at high osmolarity.

  Microbios 20010101

• The loach Misgurnus anguillicaudatus reduces amino acid catabolism and accumulates alanine and glutamine during aerial exposure.

  Physiological and biochemical zoology : PBZ 20010101

• A model of dynamic side-chain--side-chain interactions in the alpha-lactalbumin molten globule.

  Protein science : a publication of the Protein Society 20010101

• Metalaxyl toxicity, uptake, and distribution in several ornamental plant species.

  Journal of environmental quality 20010101

• Ion chromatographic analysis of selected free amino acids and cations to investigate the change of nitrogen metabolism by herbicide stress in soybean (glycine max).

  Journal of agricultural and food chemistry 20010101

• Comparative functional study of clonal insulin-secreting cells cultured in five commercially available tissue culture media.

  Cell transplantation 20010101

• Hepatic transport of gluconeogenic substrates during tumor growth in the rat.

  Cancer investigation 20010101

• Nonprotein amino acids in edible lentil and garden pea seedlings.

  Amino acids 20010101

• Alanine scanning mutagenesis of the human erythrocyte glucose transporter putative ATP binding domain.

  Blood cells, molecules & diseases 20010101

• Effect of a meal feeding schedule on hepatic glycogen synthesis and gluconeogenesis in rats.

  Journal of biomedical science 20010101

• Absorption of leucine, alanine and lysine from the rumen.

  Acta veterinaria Hungarica 20010101

• Functional examination of microencapsulated bioengineered insulin-secreting beta-cells.

  Cell biology international 20010101

• Contributions of AMPA- and kainate-sensitive receptors to the photopic electroretinogram of the Xenopus retina.

  Visual neuroscience 20010101

• Stabilization of cauliflower mosaic virus P3 tetramer by covalent linkage.

  Microbiology and immunology 20010101

• Xemilofiban/orbofiban: insight into drug development.

  Cardiovascular drug reviews 20010101

• Water-soluble L-alanine and related oligopeptide conjugates with poly[(R,S)-3-hydroxybutanoic acid] oligomers, synthesis and structural studies by means of electrospray ionization multistage mass spectrometry.

  Journal of biomaterials science. Polymer edition 20010101

• The genome of Mycobacterium leprae: a minimal mycobacterial gene set.

  Genome biology 20010101

• Peptidyl transferase activity of tRNA: a quantum chemical study.

  Indian journal of biochemistry & biophysics 20010101

• Effect of turfgrass cover and irrigation on soil mobility and dissipation of mefenoxam and propiconazole.

  Journal of environmental quality 20010101

• Resolution, configurational assignment, and enantiopharmacology at glutamate receptors of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) and demethyl-ACPA.

  Chirality 20010101

• The inhibitory mechanism of rebamipide on the mediator release in the guinea pig lung mast cells activated with specific antigen-antibody reactions.

  Pharmacology 20010101

• Formation of bioorganic compounds in simulated planetary atmospheres by high energy particles or photons.

  Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20010101

• Catalysis of peptide formation by inorganic oxides: high efficiency of alumina under mild conditions on the Earth-like planets.

  Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20010101

• Limited heat-shock protein 72 induction in Caco-2 cells by L-glutamine.

  Digestion 20010101

• Epibrassinolide increases plant drought resistance.

  Doklady. Biochemistry and biophysics 20010101

• Relation between the flexibility of the WPD loop and the activity of the catalytic domain of protein tyrosine phosphatase SHP-1.

  Journal of cellular biochemistry 20010101

• Efficient synthesis of pyrenylalanine.

  Amino acids 20010101

• Conformational analysis of thiopeptides: free energy calculations on the effects of thio-substitutions on the conformational distributions of alanine dipeptides.

  Journal of molecular graphics & modelling 20010101

• Broad-spectrum determination of pesticides in groundwater by gas chromatography with electron capture detection, nitrogen-phosphorus detection, and tandem mass spectrometry.

  Journal of AOAC International 20010101

• Site-directed mutagenesis of heparin-binding EGF-like growth factor (HB-EGF): analysis of O-glycosylation sites and properties.

  Growth factors (Chur, Switzerland) 20010101

• New reagents, reactions, and peptidomimetics for drug design.

  Biopolymers 20010101

• Extended form of a retro-inverso peptide stabilized by beta-sheet unidirectional H-bonds: Crystallographic and NMR evidence.

  Biopolymers 20010101

• No association found between the Ala54Thr polymorphism of FABP2 gene and obesity and obesity with dyslipidemia in Japanese schoolchildren.

  Journal of atherosclerosis and thrombosis 20010101

• Synthesis and binding properties of deltorphin I analogues containing (R) and (S)-alpha-hydroxymethylnaphtylalanine.

  Acta biochimica Polonica 20010101

• Conformational properties of N',N'-dimethylamides of N-acetyldehydroalanine and N-acetyl-(Z)-dehydrophenylalanine.

  Acta biochimica Polonica 20010101

• Alterations of amino acids and monoamine metabolism in male Fmr1 knockout mice: a putative animal model of the human fragile X mental retardation syndrome.

  Neural plasticity 20010101

• Combined administration of glucose precursors is more efficient than that of glucose itself in recovery from hypoglycemia.

  Research communications in molecular pathology and pharmacology 20010101

• Amelioration of carbon tetrachloride-induced hepatotoxicity by terpenoid extract from leaves of Vernonia amydgalina.

  African journal of medicine and medical sciences 20010101

• Characterization of the binding site on the formyl peptide receptor using three receptor mutants and analogs of Met-Leu-Phe and Met-Met-Trp-Leu-Leu.

  The Journal of biological chemistry 20001215

• The role of selenocysteine 133 in catalysis by the human type 2 iodothyronine deiodinase.

  Endocrinology 20001201

• Activity of allelic variants of Pi class human glutathione S-transferase toward chlorambucil.

  Biochemical and biophysical research communications 20001111

• Structure-function study and anti-HIV activity of synthetic peptide analogues derived from viral chemokine vMIP-II.

  Biochemistry 20001107

• Neonatal mouse cardiac myocytes exhibit cardioprotection induced by hypoxic and pharmacologic preconditioning and by transgenic overexpression of human Cu/Zn superoxide dismutase.

  Journal of molecular and cellular cardiology 20001001

• A QSAR study investigating the effect of L-alanine ester variation on the anti-HIV activity of some phosphoramidate derivatives of d4T.

  Bioorganic & medicinal chemistry letters 20000918

• Effect of rebamipide on prostaglandin EP4 receptor gene expression in rat gastric mucosa.

  The Journal of laboratory and clinical medicine 20000701

• Synthesis and enantioselectivity of the antiviral effects of (R,Z)-,(S,Z)-methylenecyclopropane analogues of purine nucleosides and phosphoralaninate prodrugs: influence of heterocyclic base, type of virus and host cells.

  Antiviral chemistry & chemotherapy 20000501

• Biosynthesis of L-alanine, a major amino acid of fibroin in Samia cynthia ricini.

  Insect biochemistry and molecular biology 20000301

• Phosphoramidate derivatives of stavudine as inhibitors of HIV: unnatural amino acids may substitute for alanine.

  Antiviral chemistry & chemotherapy 20000301

• Alpha-ketoacids are potent slow binding inhibitors of the hepatitis C virus NS3 protease.

  Biochemistry 20000222

• Importance of the alanine methyl ester side chain for the biological activity profile of dual-function phenyl phosphate derivatives of bromo-methoxy-zidovudine.

  Antiviral chemistry & chemotherapy 20000101

• Binding pockets of the beta(1)- and beta(2)-adrenergic receptors for subtype-selective agonists.

  Molecular pharmacology 19991101

• Critical residues influence the affinity and selectivity of alpha-conotoxin MI for nicotinic acetylcholine receptors.

  Biochemistry 19991005

• In vitro induction of human immunodeficiency virus type 1 variants resistant to phosphoralaninate prodrugs of Z-methylenecyclopropane nucleoside analogues.

  Antimicrobial agents and chemotherapy 19991001

• Structure-based design of non-nucleoside reverse transcriptase inhibitors of drug-resistant human immunodeficiency virus.

  Antiviral chemistry & chemotherapy 19990901

• Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists.

  Chemistry & biology 19990801

• Synthesis and antiviral activity of phosphoralaninate derivatives of methylenecyclopropane analogues of nucleosides.

  Antiviral research 19990801

• Substitution of the two carboxyl-terminal serines by alanine causes retention of MAL, a component of the apical sorting machinery, in the endoplasmic reticulum.

  Biochemical and biophysical research communications 19990624

• Design and synthesis of a potent cyclic analogue of the myelin basic protein epitope MBP72-85: importance of the Ala81 carboxyl group and of a cyclic conformation for induction of experimental allergic encephalomyelitis.

  Journal of medicinal chemistry 19990408

• CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding.

  Molecular pharmacology 19990301

• Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A1 receptors.

  Biochemical pharmacology 19981201

• Lactate cannot substitute for alanine in d4T-based anti-HIV nucleotide prodrugs--despite efficient esterase-mediated hydrolysis.

  Bioorganic & medicinal chemistry letters 19981103

• Duplication of the Rdl GABA receptor subunit gene in an insecticide-resistant aphid, Myzus persicae.

  Molecular & general genetics : MGG 19981101

• Rebamipide: overview of its mechanisms of action and efficacy in mucosal protection and ulcer healing.

  Digestive diseases and sciences 19980901

• D4T-5'-[p-bromophenyl methoxyalaninyl phosphate] as a potent and non-toxic anti-human immunodeficiency virus agent.

  Antiviral chemistry & chemotherapy 19980901

• Phosphinothricin-tripeptide synthetases from Streptomyces viridochromogenes.

  Biochemistry 19980210

• Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus.

  FEBS letters 19970630

• Structure-function relationships of omega-conotoxin GVIA. Synthesis, structure, calcium channel binding, and functional assay of alanine-substituted analogues.

  The Journal of biological chemistry 19970502

• Analysis of the contribution of the hinge region of human neutrophil collagenase (HNC, MMP-8) to stability and collagenolytic activity by alanine scanning mutagenesis.

  FEBS letters 19970317

• Distinct sequences of AKH/RPCH family members in beetle (Scarabaeus-species) corpus cardiacum contain three aromatic amino acid residues.

  Biochemical and biophysical research communications 19970103

• Induction of p21 mediated by reactive oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells.

  The Journal of biological chemistry 19961213

• Antiretrovirus specificity and intracellular metabolism of 2',3' -didehydro-2',3'-dideoxythymidine (stavudine) and its 5'-monophosphate triester prodrug So324.

  Molecular pharmacology 19961101

• Enzymatic synthesis of two isoxazolylalanine isomers by cysteine synthases in Lathyrus species.

  Biological & pharmaceutical bulletin 19960901

• A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid.

  Journal of medicinal chemistry 19960802

• Mechanism of anti-HIV action of masked alaninyl d4T-MP derivatives.

  Proceedings of the National Academy of Sciences of the United States of America 19960709

• Inhibitors of human immunodeficiency virus type 1 derived from gp41 transmembrane protein: structure--activity studies.

  Journal of medicinal chemistry 19960705

• Interaction of L-cysteine with a human excitatory amino acid transporter.

  The Journal of physiology 19960601

• Conformational study based on simulated annealing and 1H NMR of peptides comprising the consensus sequence Arg5-Asp-Val-Arg-Gly9: effects of the substitution Ser 12 by Ala 12 or of 3 residues deletion at the N-terminus.

  Journal of biomolecular structure & dynamics 19960201

• Rebamipide, novel prostaglandin-inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine.

  Digestive diseases and sciences 19951101

• A synthetic inhibitor of the mitogen-activated protein kinase cascade.

  Proceedings of the National Academy of Sciences of the United States of America 19950815

• Two-dimensional 1H NMR study of a tetradecapeptide with the consensus sequence Arg5-Asp-Val-Arg-Gly9: structural effects of the outside substitution Ser12 by Ala12.

  Journal of biomolecular structure & dynamics 19950401

• Drosophila GABA-gated chloride channel: modified [3H]EBOB binding site associated with Ala-->Ser or Gly mutants of Rdl subunit.

  Life sciences 19950101

• Alaproclate acts as a potent, reversible and noncompetitive antagonist of the NMDA receptor coupled ion flow.

  The Journal of pharmacology and experimental therapeutics 19941201

• Use of a dehydroalanine-containing peptide as an efficient inhibitor of tripeptidyl peptidase II.

  Archives of biochemistry and biophysics 19941101

• Preventive effect of betamipron on nephrotoxicity and uptake of carbapenems in rabbit renal cortex.

  Japanese journal of pharmacology 19940901

• Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring.

  Biochemistry 19940823

• A unique amino acid of the Drosophila GABA receptor with influence on drug sensitivity by two mechanisms.

  The Journal of physiology 19940815

• Central activity of 2-amino-3-phosphonopropionic acid (AP3) and its N-methyl analog.

  Polish journal of pharmacology 19940101

• Stimulation of prostaglandin biosynthesis mediates gastroprotective effect of rebamipide in rats.

  Digestive diseases and sciences 19930801

• The role of receptor binding in drug discovery.

  Journal of natural products 19930401

• Free radical scavenging activity of the novel anti-ulcer agent rebamipide studied by electron spin resonance.

  Arzneimittel-Forschung 19930301

• Synthesis and antifungal activities of pradimicin A derivatives modification of the alanine moiety.

  The Journal of antibiotics 19930301

• Synthesis and antifungal activities of alanine-exchanged analogs of pradimicin A.

  The Journal of antibiotics 19930301

• C-terminal labeling of ribonuclease A with an extrinsic fluorescent probe by carboxypeptidase Y-catalyzed transpeptidation in the presence of urea.

  Analytical biochemistry 19930215

• Immunosuppressive activity of alanine analogs of cyclolinopeptide A.

  Archivum immunologiae et therapiae experimentalis 19930101

• Effect of rebamipide on mucus secretion by endogenous prostaglandin-independent mechanism in rat gastric mucosa.

  Arzneimittel-Forschung 19921201

• The presence of free D-serine, D-alanine and D-proline in human plasma.

  Experientia 19921015

• Distinct agonist- and antagonist-binding sites on the glycine receptor.

  Neuron 19920901

• Altered glucose metabolism in adriamycin-induced heart failure.

  Biochimica et biophysica acta 19920116

• Biosynthesis of beta-(isoxazolin-5-on-2-yl)alanine, the precursor of the neurotoxic amino acid beta-N-oxalyl-L-alpha,beta-diaminopropionic acid.

  Chemical & pharmaceutical bulletin 19911201

• 1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase.

  Archives of biochemistry and biophysics 19911201

• D-alanine inhibits methamphetamine-induced hyperactivity in rats.

  European journal of pharmacology 19910904

• Antithrombin Glasgow II: alanine 382 to threonine mutation in the serpin P12 position, resulting in a substrate reaction with thrombin.

  British journal of haematology 19910901

• Identification of a D-alanine-containing polypeptide precursor for the peptide opioid, dermorphin.

  The Journal of biological chemistry 19910405

• A quenched fluorescent substrate for thimet peptidase containing a new fluorescent amino acid, DL-2-amino-3-(7-methoxy-4-coumaryl)propionic acid.

  The Biochemical journal 19910215

• Glucosamine-6-phosphate synthase from Escherichia coli: determination of the mechanism of inactivation by N3-fumaroyl-L-2,3-diaminopropionic derivatives.

  Biochemistry 19900417

• Hypotension decreases GABA levels in brainstem regions of the rat.

  Clinical and experimental hypertension. Part A, Theory and practice 19900101

• Functional interaction among catalytic residues in subtilisin BPN'.

  Proteins 19900101

• Intrathecal GABA, glycine, taurine or beta-alanine elicits dyskinetic movements in mice.

  Pharmacology, biochemistry, and behavior 19890201

• Structure-activity relationship of a novel antitumor ansamycin antibiotic trienomycin A and related compounds.

  The Journal of antibiotics 19880901

• Antitumor activity of trienomycin A on murine tumors.

  The Journal of antibiotics 19871201

• Metabolic and hemodynamic effects of nicardipine during pacing-induced angina pectoris.

  The American journal of cardiology 19870201

• A single amino acid substitution in an ectopic alpha subunit of a human carcinoma choriogonadotropin.

  The Journal of biological chemistry 19860815

• Synthesis and structure-activity relationships of antibacterial phosphonopeptides incorporating (1-aminoethyl)phosphonic acid and (aminomethyl)phosphonic acid.

  Journal of medicinal chemistry 19860101

• Synthesis and release of luteinizing hormone in vitro by rat anterior pituitary cells: effects of gallopamil hydrochloride (D600) and pimozide.

  Endocrinology 19851001

• Cytochemical localization and biochemical evaluation of a lysosomal serine protease in lung: dipeptidyl peptidase II in the normal rat.

  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 19850701

• In vivo and in vitro studies on the potentiation of muscarinic receptor stimulation by alaproclate, a selective 5-HT uptake blocker.

  Journal of neural transmission 19850101

• The effects of alaproclate on the pupillary responses to tyramine, phenylephrine and pilocarpine in depressed patients.

  Psychopharmacology 19850101

• Identification of the active-site residue of gamma-cystathionase labeled by the suicide inactivator beta, beta, beta-trifluoroalanine.

  Biochemistry 19820803

• Beta-alanine synthesis in Escherichia coli.

  Journal of bacteriology 19800301

• An incipient 3(10) helix in Piv-Pro-Pro-Ala-NHMe as a model for peptide folding.

  Nature 19790906

• Investigations on the potential nephrotoxicity of cefazedone and gentamicin and of their combination, in comparison with the combination of cefazolin and cephalothin with gentamicin.

  Arzneimittel-Forschung 19790101

• Utilization of a depsipeptide substrate for trapping acyl-enzyme intermediates of penicillin-sensitive D-alanine carboxypeptidases.

  Proceedings of the National Academy of Sciences of the United States of America 19780101

• Theophylline stimulation of gluconeogenesis from alanine in normal and sympathectomized rats.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 19760101

• The renaturation of reduced polyalanyl-chymotrypsinogen and chymotrypsinogen.

  European journal of biochemistry 19751115

• The role of serine-123 in the activity and specificity of ribonuclease. Reactivation of ribonuclease 1-118 by the synthetic COOH-terminal tetradecapeptide, ribonuclease 111-124, and its O-methylserine and alanine analogs.

  The Journal of biological chemistry 19750225

• Synthesis by conventional methods of human growth hormone peptide fragments. I.

  International journal of peptide and protein research 19750101

• Resistance to D-cycloserine in the tubercle bacilli: mutation rate and transport of alanine in parental cells and drug-resistant mutants.

  Applied microbiology 19710501

• Isolation and characterization of uridine diphosphate-N-glycolylmuramyl-L-alanyl-gamma-D-glutamyl-meso-alpha,alpha'-diaminopimelic acid from Mycobacterium tuberculosis.

  Biochemical and biophysical research communications 19700408

• Susceptibility of mycobacterial D-alanyl-D-alanine synthetase to D-cycloserine.

  The American review of respiratory disease 19691001