338747-41-4 | 1-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
5mg	95%	in stock	$80.00	$56.00
10mg	95%	in stock	$124.00	$87.00
25mg	95%	in stock	$290.00	$203.00
100mg	95%	in stock	$322.00	$225.00
250mg	95%	in stock	$575.00	$402.00
1g	95%	in stock	$1,032.00	$722.00

Description

• Catalog Number: AG12646
• Chemical Name: 1-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• CAS Number: 338747-41-4
• Molecular Formula: C18H15NO4
• Molecular Weight: 309.316
• MDL Number: MFCD01315710
• SMILES: COc1ccc(cc1)Cn1cc(C(=O)O)c(=O)c2c1cccc2

Computed Properties

• Complexity: 493
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 23
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 4
• XLogP3: 3.4

Literature

• Discovery of a selective allosteric M1 receptor modulator with suitable development properties based on a quinolizidinone carboxylic acid scaffold.

  Journal of medicinal chemistry 20110714

• Quinolizidinone carboxylic acid selective M1 allosteric modulators: SAR in the piperidine series.

  Bioorganic & medicinal chemistry letters 20110315

• Heterocyclic fused pyridone carboxylic acid M(1) positive allosteric modulators.

  Bioorganic & medicinal chemistry letters 20100415

• N-heterocyclic derived M1 positive allosteric modulators.

  Bioorganic & medicinal chemistry letters 20100215

• Pyridine containing M(1) positive allosteric modulators with reduced plasma protein binding.

  Bioorganic & medicinal chemistry letters 20100115

• Parallel synthesis of N-biaryl quinolone carboxylic acids as selective M(1) positive allosteric modulators.

  Bioorganic & medicinal chemistry letters 20100115

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501