3389-21-7 | 3-(2-Bromoethyl)-1H-indole

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$34.00	$24.00
5g	97%	in stock	$118.00	$83.00
100g	97%	in stock	$2,344.00	$1,641.00

Description

• Catalog Number: AB63104
• Chemical Name: 3-(2-Bromoethyl)-1H-indole
• CAS Number: 3389-21-7
• Molecular Formula: C10H10BrN
• Molecular Weight: 224.0971
• MDL Number: MFCD00130155
• SMILES: BrCCc1c[nH]c2c1cccc2

Computed Properties

• Complexity: 149
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 3.3

Upstream Synthesis Route

3-(2-Bromoethyl)-1H-indole is a versatile compound commonly used in chemical synthesis for its unique reactivity and structural properties. With its bromoethyl group strategically positioned on the indole ring, this compound serves as a valuable building block for the synthesis of various biologically active molecules and pharmaceutical intermediates. One prominent application of 3-(2-Bromoethyl)-1H-indole is its role in the synthesis of indole-based anticancer agents. By utilizing the bromoethyl group as a handle for further functionalization, chemists can introduce specific molecular modifications to enhance the potency and specificity of the resulting compounds. This versatility makes 3-(2-Bromoethyl)-1H-indole a crucial component in the development of novel cancer therapeutics.Moreover, this compound is also used in the synthesis of indole derivatives with potential antimicrobial properties. The incorporation of the bromoethyl group allows for the attachment of various substituents to fine-tune the biological activity of the synthesized molecules. By leveraging the reactivity of the bromoethyl moiety, researchers can explore the structure-activity relationships of these indole derivatives and optimize their antimicrobial efficacy.In addition to its significance in medicinal chemistry, 3-(2-Bromoethyl)-1H-indole finds applications in material science and organic synthesis. Its reactive bromoethyl group enables chemists to forge carbon-carbon and carbon-heteroatom bonds, facilitating the construction of complex molecular structures for applications in diverse fields.Overall, the versatility and reactivity of 3-(2-Bromoethyl)-1H-indole make it a valuable tool in chemical synthesis, particularly in the development of biologically active compounds and advanced materials.

Literature

• A novel tool for studying auxin-metabolism: the inhibition of grapevine indole-3-acetic acid-amido synthetases by a reaction intermediate analogue.

  PloS one 20120101

• Stable diplatinum complexes with functional thiolato bridges from dialkylation of [Pt2(mu-S)2(P-P)2] [P-P=2 x PPh3, Ph2P(CH2)3PPh2].

  Dalton transactions (Cambridge, England : 2003) 20070928