344-25-2 | (2R)-pyrrolidine-2-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$6.00	$4.00
25g	98%	in stock	$12.00	$8.00
100g	98%	in stock	$43.00	$30.00
250g	98%	in stock	$55.00	$38.00
500g	98%	in stock	$83.00	$58.00

Description

• Catalog Number: AB46003
• Chemical Name: (2R)-pyrrolidine-2-carboxylic acid
• CAS Number: 344-25-2
• Molecular Formula: C5H9NO2
• Molecular Weight: 115.1305
• MDL Number: MFCD00064317
• SMILES: OC(=O)[C@H]1CCCN1

Computed Properties

• Complexity: 103
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• Undefined Atom Stereocenter Count: 1
• XLogP3: -2.5

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• Chemical protein synthesis by chemoselective α-ketoacid-hydroxylamine (KAHA) ligations with 5-oxaproline.

  Angewandte Chemie (International ed. in English) 20120521

• Hydrophobic substituent effects on proline catalysis of aldol reactions in water.

  The Journal of organic chemistry 20120518

• Congeneric bio-adhesive mussel foot proteins designed by modified prolines revealed a chiral bias in unnatural translation.

  Biochemical and biophysical research communications 20120518

• A study of proline metabolism in canola (Brassica napus L.) seedlings under salt stress.

  Molecules (Basel, Switzerland) 20120516

• Evaluation of a tandem gas chromatography/time-of-flight mass spectrometry metabolomics platform as a single method to investigate the effect of starvation on whole-animal metabolism in rainbow trout (Oncorhynchus mykiss).

  The Journal of experimental biology 20120515

• New genetic discoveries and treatment for hepatitis C.

  JAMA 20120509

• Probing the caveolin-1 P132L mutant: critical insights into its oligomeric behavior and structure.

  Biochemistry 20120508

• Infrared probing of 4-azidoproline conformations modulated by azido configurations.

  The journal of physical chemistry. B 20120503

• Rapid method for proline determination in grape juice and wine.

  Journal of agricultural and food chemistry 20120502

• Stereocontrolled synthesis of vicinal diamines by organocatalytic asymmetric Mannich reaction of N-protected aminoacetaldehydes: formal synthesis of (-)-agelastatin A.

  Journal of the American Chemical Society 20120502

• Metabolism of select amino acids in bacteria from the pig small intestine.

  Amino acids 20120501

• Alleviation of salt stress in wheat seedlings by mammalian sex hormones.

  Journal of the science of food and agriculture 20120501

• Simultaneous accumulation of proline and trehalose in industrial baker's yeast enhances fermentation ability in frozen dough.

  Journal of bioscience and bioengineering 20120501

• Interaction of influenza A virus matrix protein with RACK1 is required for virus release.

  Cellular microbiology 20120501

• Review and management of drug interactions with boceprevir and telaprevir.

  Hepatology (Baltimore, Md.) 20120501

• [Use of boceprevir and telaprevir in patients with hepatitis C virus infection (practical considerations)].

  Gastroenterologia y hepatologia 20120501

• Differential response of salt stress on Brassica juncea: photosynthetic performance, pigment, proline, D1 and antioxidant enzymes.

  Plant physiology and biochemistry : PPB 20120501

• Pro12Ala polymorphism of the PPAR-γ2 gene, metabolic syndrome and response to metformin in clozapine-treated patients.

  Schizophrenia research 20120501

• Biochemical and physiological responses of rice (Oryza sativa L.) as influenced by Trichoderma harzianum under drought stress.

  Plant physiology and biochemistry : PPB 20120501

• Synthesis and in vitro inhibition properties of oligonucleotide conjugates carrying amphipathic proline-rich peptide derivatives of the sweet arrow peptide (SAP).

  Molecular diversity 20120501

• Hepatitis C and substance use: new treatments and novel approaches.

  Current opinion in psychiatry 20120501

• A practical guide for the use of boceprevir and telaprevir for the treatment of hepatitis C.

  Journal of viral hepatitis 20120501

• High-throughput cryopreservation of plant cell cultures for functional genomics.

  Plant & cell physiology 20120501

• Hepatitis C therapy update.

  Current opinion in gastroenterology 20120501

• Proline kink angle distributions for GWALP23 in lipid bilayers of different thicknesses.

  Biochemistry 20120501

• New direct-acting antiviral agents for the treatment of hepatitis C virus infection and perspectives.

  Gut 20120501

• Regulation of proline metabolism in mycobacteria and its role in carbon metabolism under hypoxia.

  Molecular microbiology 20120501

• Discovery of boceprevir, a direct-acting NS3/4A protease inhibitor for treatment of chronic hepatitis C infections.

  Trends in pharmacological sciences 20120501

• Update on the management and treatment of hepatitis C virus infection: recommendations from the Department of Veterans Affairs Hepatitis C Resource Center Program and the National Hepatitis C Program Office.

  The American journal of gastroenterology 20120501

• New virologic tools for management of chronic hepatitis B and C.

  Gastroenterology 20120501

• Maximizing opportunities and avoiding mistakes in triple therapy for hepatitis C virus.

  Gastroenterology 20120501

• Management of patients coinfected with HCV and HIV: a close look at the role for direct-acting antivirals.

  Gastroenterology 20120501

• Genetic factors and hepatitis C virus infection.

  Gastroenterology 20120501

• AKAP79 modulation of L-type channels involves disruption of intramolecular interactions in the CaV1.2 subunit.

  Channels (Austin, Tex.) 20120501

• (S)-Proline-catalyzed nitro-Michael reactions: towards a better understanding of the catalytic mechanism and enantioselectivity.

  Organic & biomolecular chemistry 20120428

• Metal cation dependence of interactions with amino acids: bond energies of Cs+ to Gly, Pro, Ser, Thr, and Cys.

  The journal of physical chemistry. A 20120426

• Synthesis and biological activity of potent HIV-1 protease inhibitors based on Phe-Pro dihydroxyethylene isosteres.

  Journal of medicinal chemistry 20120426

• Highly enantioselective proline-catalysed direct aldol reaction of chloroacetone and aromatic aldehydes.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20120423

• Chronic inhibition of nuclear factor kappa B attenuates aldosterone/salt-induced renal injury.

  Life sciences 20120420

• Isoleucine-catalyzed direct asymmetric aldol addition of enolizable aldehydes.

  Organic letters 20120420

• Targeted therapies for hepatitis C reach the clinic.

  Chemistry & biology 20120420

• Interaction of the histone mRNA hairpin with stem-loop binding protein (SLBP) and regulation of the SLBP-RNA complex by phosphorylation and proline isomerization.

  Biochemistry 20120417

• Interaction of proline, sugars, and anthocyanins during photosynthetic acclimation of Arabidopsis thaliana to drought stress.

  Journal of plant physiology 20120415

• Exogenous proline and trehalose promote recovery of rice seedlings from salt-stress and differentially modulate antioxidant enzymes and expression of related genes.

  Journal of plant physiology 20120415

• Overexpression of OsHsp17.0 and OsHsp23.7 enhances drought and salt tolerance in rice.

  Journal of plant physiology 20120415

• Toxicarioside A inhibits SGC-7901 proliferation, migration and invasion via NF-κB/bFGF signaling.

  World journal of gastroenterology 20120414

• The cis-4-amino-L-proline residue as a scaffold for the synthesis of cyclic and linear endomorphin-2 analogues.

  Journal of medicinal chemistry 20120412

• Efficient, chemoenzymatic process for manufacture of the Boceprevir bicyclic [3.1.0]proline intermediate based on amine oxidase-catalyzed desymmetrization.

  Journal of the American Chemical Society 20120411

• Stereoselectivities of histidine-catalyzed asymmetric aldol additions and contrasts with proline catalysis: a quantum mechanical analysis.

  Journal of the American Chemical Society 20120411

• Organocatalysis in synthesis: L-proline as an enantioselective catalyst in the synthesis of pyrans and thiopyrans.

  Molecules (Basel, Switzerland) 20120410

• Organocatalytic asymmetric 1,4-addition of aldehydes to acridiniums catalyzed by a diarylprolinol silyl ether.

  The Journal of organic chemistry 20120406

• Local control of the cis-trans isomerization and backbone dihedral angles in peptides using trifluoromethylated pseudoprolines.

  The journal of physical chemistry. B 20120405

• Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal.

  Cell metabolism 20120404

• Phosphorylation regulates assembly of the caspase-6 substrate-binding groove.

  Structure (London, England : 1993) 20120404

• Stability and structure of protein-lipoamino acid colloidal particles: toward nasal delivery of pharmaceutically active proteins.

  Langmuir : the ACS journal of surfaces and colloids 20120403

• Olfactory sensitivity for six amino acids: a comparative study in CD-1 mice and spider monkeys.

  Amino acids 20120401

• Unusual fragmentation of Pro-Ser/Thr-containing peptides detected in collision-induced dissociation spectra.

  Journal of the American Society for Mass Spectrometry 20120401

• Fragmentation reactions of b(5) and a (5) ions containing proline--the structures of a(5) ions.

  Journal of the American Society for Mass Spectrometry 20120401

• Meta-analysis shows significant association of the TP53 Arg72Pro with ovarian cancer risk.

  Molecular biology reports 20120401

• Clinical relevance of detectable but not quantifiable hepatitis C virus RNA during boceprevir or telaprevir treatment.

  Hepatology (Baltimore, Md.) 20120401

• Deep brain stimulation in Pantothenate Kinase Associated Neurodegeneration: challenges for the future.

  European journal of neurology 20120401

• Pantothenate kinase-associated neurodegeneration in Korea: recurrent R440P mutation in PANK2 and outcome of deep brain stimulation.

  European journal of neurology 20120401

• Provisional guidance on the use of hepatitis C virus protease inhibitors for treatment of hepatitis C in HIV-infected persons.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120401

• Conformational preferences of proline derivatives incorporated into vasopressin analogues: NMR and molecular modelling studies.

  Chemical biology & drug design 20120401

• Rectal absorption of vigabatrin, a substrate of the proton coupled amino acid transporter (PAT1, Slc36a1), in rats.

  Pharmaceutical research 20120401

• Asymmetric Michael reaction of aldehydes with β-nitroalkenes catalyzed by pyrrolidine-camphor derived organocatalysts bearing hydrogen-bond donors.

  Chirality 20120401

• Excess copper induced oxidative stress and response of antioxidants in rice.

  Plant physiology and biochemistry : PPB 20120401

• Mechanism of action and specificity of antimicrobial peptides designed based on buforin IIb.

  Peptides 20120401

• Comparative effect of 28 homobrassinolide and salicylic acid in the amelioration of NaCl stress in Brassica juncea L.

  Plant physiology and biochemistry : PPB 20120401

• Gly or Ala substitutions for Pro(210)Thr(211)Asn(212) at the β8-β9 turn of subtilisin Carlsberg increase the catalytic rate and decrease thermostability.

  Biochimica et biophysica acta 20120401

• Solution-phase synthesis and evaluation of tetraproline chiral stationary phases.

  Chirality 20120401

• [Current indications for triple therapy in hepatitis C virus infection].

  Gastroenterologia y hepatologia 20120401

• Enhanced salt tolerance of tomatoes by exogenous salicylic acid applied through rooting medium.

  Omics : a journal of integrative biology 20120401

• Review of boceprevir and telaprevir for the treatment of chronic hepatitis C.

  Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20120401

• Boceprevir.

  Prescrire international 20120401

• Pure culture of Metarhizium anisopliae LHL07 reprograms soybean to higher growth and mitigates salt stress.

  World journal of microbiology & biotechnology 20120401

• Behavioral changes induced by long-term proline exposure are reversed by antipsychotics in zebrafish.

  Progress in neuro-psychopharmacology & biological psychiatry 20120330

• (S)-(-)-N-(pentafluorobenzylcarbamoyl)prolyl chloride: a chiral derivatisation reagent designed for gas chromatography/negative ion chemical ionisation mass spectrometry of amino compounds.

  Rapid communications in mass spectrometry : RCM 20120330

• Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease.

  Cell 20120330

• Mechanism and optimisation of the homoboroproline bifunctional catalytic asymmetric aldol reaction: Lewis acid tuning through in situ esterification.

  Organic & biomolecular chemistry 20120328

• Pro42 and Val45 of staphylokinase modulate intermolecular interactions of His43-Tyr44 pair and specificity of staphylokinase-plasmin activator complex.

  FEBS letters 20120323

• The transmembrane prolines of the mitochondrial ADP/ATP carrier are involved in nucleotide binding and transport and its biogenesis.

  The Journal of biological chemistry 20120323

• Biomechanical characterization of a desminopathy in primary human myoblasts.

  Biochemical and biophysical research communications 20120323

• Expedient synthesis of pseudo-Pro-containing peptides: towards constrained peptidomimetics and foldamers.

  Organic & biomolecular chemistry 20120321

• Three ring posttranslational circuses: insertion of oxazoles, thiazoles, and pyridines into protein-derived frameworks.

  ACS chemical biology 20120316

• Bradykinin-potentiating peptides: beyond captopril.

  Toxicon : official journal of the International Society on Toxinology 20120315

• Exogenous mammalian sex hormones mitigate inhibition in growth by enhancing antioxidant activity and synthesis reactions in germinating maize seeds under salt stress.

  Journal of the science of food and agriculture 20120315

• High frequency of Neuropeptide Y Leu7Pro polymorphism in an Iranian population and its association with coronary artery disease.

  Gene 20120315

• Direct evidence for CH···π interaction mediated stabilization of Pro-cisPro bond in peptides with Pro-Pro-aromatic motifs.

  Journal of the American Chemical Society 20120314

• Role of coupled dynamics in the catalytic activity of prokaryotic-like prolyl-tRNA synthetases.

  Biochemistry 20120313

• Stabilization of proline enamine carboxylates by amine bases.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20120312

• [Hungarian consensus guideline for the diagnosis and treatment of B, C, and D viral hepatitis].

  Orvosi hetilap 20120311

• A conserved proline switch on the ribosome facilitates the recruitment and binding of trGTPases.

  Nature structural & molecular biology 20120311

• A new protocol for the treatment of the chronic venous ulcers of the lower limb.

  Clinical and experimental medicine 20120301

• Isolation and functional characterization of a Medicago sativa L. gene, MsLEA3-1.

  Molecular biology reports 20120301

• Enhancement of anthraquinone production in Morinda citrifolia cell suspension cultures after stimulation of the proline cycle with two proline analogs.

  Biotechnology letters 20120301

• HLA-B*08:01:08- joining the fold of silent alpha-1 proline mutations in HLA-B.

  Tissue antigens 20120301

• Peptidomimetic escape mechanisms arise via genetic diversity in the ligand-binding site of the hepatitis C virus NS3/4A serine protease.

  Gastroenterology 20120301

• Microbial consortium-mediated reprogramming of defence network in pea to enhance tolerance against Sclerotinia sclerotiorum.

  Journal of applied microbiology 20120301

• Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models.

  Neurobiology of disease 20120301

• Disfavoring macrocycle b fragments by constraining torsional freedom: the 'twisted' case of QWFGLM b6.

  Journal of the American Society for Mass Spectrometry 20120301

• Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 sodium channels.

  Biochimica et biophysica acta 20120301

• Biochemical characterization and identification of differentially expressed candidate genes in salt stressed sugarcane.

  Plant science : an international journal of experimental plant biology 20120301

• The effect of biradical concentration on the performance of DNP-MAS-NMR.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20120301

• UK consensus guidelines for the use of the protease inhibitors boceprevir and telaprevir in genotype 1 chronic hepatitis C infected patients.

  Alimentary pharmacology & therapeutics 20120301

• Chromium-induced tropane alkaloid production and H6H gene expression in Atropa belladonna L. (Solanaceae) in vitro-propagated plantlets.

  Plant physiology and biochemistry : PPB 20120301

• New drugs 2012 part I.

  Nursing 20120301

• Exome sequencing reveals DNAJB6 mutations in dominantly-inherited myopathy.

  Annals of neurology 20120301

• Reduced dimensionality 3D HNCAN for unambiguous HN, CA and N assignment in proteins.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20120301

• Protease inhibitors: silver bullets for chronic hepatitis C infection?

  Cleveland Clinic journal of medicine 20120301

• Effect of amino acids on red pigments and citrinin production in Monascus ruber.

  Journal of food science 20120301

• Boceprevir: an oral protease inhibitor for the treatment of chronic HCV infection.

  Expert review of anti-infective therapy 20120301

• Does antiviral therapy reduce the risk of hepatocellular carcinoma in patients with chronic hepatitis C?

  Minerva gastroenterologica e dietologica 20120301

• [Response of isozyme and stress indexes of Coptis chinensis to UV-B radiation].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20120301

• Proline 107 is a major determinant in maintaining the structure of the distal pocket and reactivity of the high-spin heme of MauG.

  Biochemistry 20120227

• A new benzotriazole-mediated stereoflexible gateway to hetero-2,5-diketopiperazines.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20120227

• Advances in proline ligation.

  Journal of the American Chemical Society 20120227

• Identification and functional characterization of the novel human ether-a-go-go-related gene (hERG) R744P mutant associated with hereditary long QT syndrome 2.

  Biochemical and biophysical research communications 20120224

• Neuronal projections from V1 to V2 in amblyopia.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120222

• Copper-catalyzed synthesis of substituted indazoles from 2-chloroarenes at low catalyst-loading.

  Organic & biomolecular chemistry 20120221

• Si-free enolate Claisen rearrangements of enamido substrates.

  Organic & biomolecular chemistry 20120221

• Total syntheses of (-)-hanishin, (-)-longamide B, and (-)-longamide B methyl ester via a novel preparation of N-substituted pyrrole-2-carboxylates [corrected].

  Organic letters 20120217

• Stylissamide X, a new proline-rich cyclic octapeptide as an inhibitor of cell migration, from an Indonesian marine sponge of Stylissa sp.

  Bioorganic & medicinal chemistry letters 20120215

• A solid-supported organocatalyst for continuous-flow enantioselective aldol reactions.

  ChemSusChem 20120213

• Annual drug update: 2011 in review.

  The Nurse practitioner 20120212

• Discovery of a novel class of potent and orally bioavailable sphingosine 1-phosphate receptor 1 antagonists.

  Journal of medicinal chemistry 20120209

• Quaternary ammonium oxidative demethylation: X-ray crystallographic, resonance Raman, and UV-visible spectroscopic analysis of a Rieske-type demethylase.

  Journal of the American Chemical Society 20120208

• Dysmorphic photoreceptors in a P23H mutant rhodopsin model of retinitis pigmentosa are metabolically active and capable of regenerating to reverse retinal degeneration.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120208

• Stereoselective synthesis of N-aryl proline amides by biotransformation-Ugi-Smiles sequence.

  Organic & biomolecular chemistry 20120207

• Effects of pathogenic proline mutations on myosin assembly.

  Journal of molecular biology 20120203

• The serine-proline turn: a novel hydrogen-bonded template for designing peptidomimetics.

  Organic letters 20120203

• A glycine-rich RNA-binding protein can mediate physiological responses in transgenic plants under salt stress.

  Molecular biology reports 20120201

• The critical role of medication adherence in the success of boceprevir and telaprevir in clinical practice.

  Journal of hepatology 20120201

• The roles of peptidyl-proline isomerases in gene regulation.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20120201

• A perspective on non-catalytic Src homology (SH) adaptor signalling proteins.

  Cellular signalling 20120201

• Hybrid proline-rich proteins: novel players in plant cell elongation?

  Annals of botany 20120201

• Hydrophilic interaction and reversed-phase ultraperformance liquid chromatography TOF-MS for serum metabonomic analysis of myocardial infarction in rats and its applications.

  Molecular bioSystems 20120201

• Resistance-associated variants in chronic hepatitis C patients treated with protease inhibitors.

  Current gastroenterology reports 20120201

• Increasing nitric oxide content in Arabidopsis thaliana by expressing rat neuronal nitric oxide synthase resulted in enhanced stress tolerance.

  Plant & cell physiology 20120201

• The effect of prolyl oligopeptidase inhibition on extracellular acetylcholine and dopamine levels in the rat striatum.

  Neurochemistry international 20120201

• Phase III results of Boceprevir in treatment naïve patients with chronic hepatitis C genotype 1.

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• Boceprevir and telaprevir for the treatment of chronic hepatitis C: safety management in clinical practice.

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• Phase III results in Genotype 1 naïve patients: predictors of response with boceprevir and telaprevir combined with pegylated interferon and ribavirin.

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• Triple therapy with telaprevir: results in hepatitis C virus-genotype 1 infected relapsers and non-responders.

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• Triple therapy with boceprevir for HCV genotype 1 infection: phase III results in relapsers and nonresponders.

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• Triple therapy for HCV genotype 1 infection: telaprevir or boceprevir?

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• Triple combination treatment for chronic hepatitis C with protease inhibitors, pegylated interferon and ribavirin: 'lead-in or no lead-in'?

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• Direct acting antivirals for the treatment of chronic hepatitis C: one pill a day for tomorrow.

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• Future treatment of patients with HCV cirrhosis.

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• Hepatitis C virus treatment pre- and post-liver transplantation.

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• Hepatitis C virus-human immunodeficiency virus coinfection.

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• What's new in HCV genotype 2 treatment.

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• Treatment of patients with genotype 3 chronic hepatitis C--current and future therapies.

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• The future for the treatment of genotype 4 chronic hepatitis C.

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• Barriers to hepatitis C treatment.

  Liver international : official journal of the International Association for the Study of the Liver 20120201

• Mutations selected in the hepatitis C virus NS3 protease domain during sequential treatment with boceprevir with and without pegylated interferon alfa-2b.

  Journal of viral hepatitis 20120201

• Treatment failure with new hepatitis C drugs.

  Expert opinion on pharmacotherapy 20120201

• Changes in the initial stages of a glucose-proline Maillard reaction model system influences dairy product quality during thermal processing.

  Journal of dairy science 20120201

• Safety of L-proline as a stabilizer for immunoglobulin products.

  Expert review of clinical immunology 20120201

• Boceprevir: a novel NS3/4 protease inhibitor for the treatment of hepatitis C.

  Pharmacotherapy 20120201

• Modulation of bovine chondrocyte metabolism by free periosteal grafts in vitro.

  The International journal of artificial organs 20120201

• Triple therapy for hepatitis C.

  JAAPA : official journal of the American Academy of Physician Assistants 20120201

• Single-molecule enzyme dynamics of monomeric sarcosine oxidase in a gold-based zero-mode waveguide.

  Applied spectroscopy 20120201

• [Raman spectroscopic study on the influence of ultraviolet-A radiation on collagen I].

  Guang pu xue yu guang pu fen xi = Guang pu 20120201

• Effects of Prolyl-Glycyl-Proline (PGP) peptide on disorders in rat mesenteric lymphatic vessel function induced by injection of substance 48/80.

  Bulletin of experimental biology and medicine 20120201

• Effect of Azotobacter vinelandii and compatible solutes on germination wheat seeds and root concentrations of sodium and potassium under salt stress.

  Pakistan journal of biological sciences : PJBS 20120201

• High glucose-induced expression of inflammatory cytokines and reactive oxygen species in cultured astrocytes.

  Neuroscience 20120127

• Bridging between organocatalysis and biocatalysis: asymmetric addition of acetaldehyde to β-nitrostyrenes catalyzed by a promiscuous proline-based tautomerase.

  Angewandte Chemie (International ed. in English) 20120127

• The 2011 E. B. Hershberg award for important discoveries in medicinally active substances: (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a GABA aminotransferase inactivator and new treatment for drug addiction and infantile spasms.

  Journal of medicinal chemistry 20120126

• Surgical stress resistance induced by single amino acid deprivation requires Gcn2 in mice.

  Science translational medicine 20120125

• Probing structural features of Alzheimer's amyloid-β pores in bilayers using site-specific amino acid substitutions.

  Biochemistry 20120124

• β-Phenylproline: the high β-turn forming propensity of proline combined with an aromatic side chain.

  Organic & biomolecular chemistry 20120121

• Tunable growth factor delivery from injectable hydrogels for tissue engineering.

  Journal of the American Chemical Society 20120118

• The proline TP53 variant stimulates likely lymphangiogenesis in an orthotopic mouse model of pancreatic cancer.

  British journal of cancer 20120117

• Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline.

  Free radical biology & medicine 20120115

• (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent γ-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction.

  Journal of medicinal chemistry 20120112

• Basic amino-acid side chains regulate transmembrane integrin signalling.

  Nature 20120112

• Crotonase catalysis enables flexible production of functionalized prolines and carbapenams.

  Journal of the American Chemical Society 20120111

• Occurrence of pipecolic acid and pipecolic acid betaine (homostachydrine) in Citrus genus plants.

  Journal of agricultural and food chemistry 20120111

• Rapid reaction kinetics of proline dehydrogenase in the multifunctional proline utilization A protein.

  Biochemistry 20120110

• Organocatalysis in water at room temperature with in-flask catalyst recycling.

  Organic letters 20120106

• Proline accumulation in baker's yeast enhances high-sucrose stress tolerance and fermentation ability in sweet dough.

  International journal of food microbiology 20120103

• Response of two mustard (Brassica juncea L.) cultivars differing in photosynthetic capacity subjected to proline.

  Protoplasma 20120101

• Drought-induced proline accumulation is uninvolved with increased nitric oxide, which alleviates drought stress by decreasing transpiration in rice.

  Journal of plant research 20120101

• Changes in the water status and osmotic solute contents in response to drought and salicylic acid treatments in four different cultivars of wheat (Triticum aestivum).

  Journal of plant research 20120101

• Dishevelled C-terminus: prolyl and histidinyl motifs.

  Acta physiologica (Oxford, England) 20120101

• A critical step for JNK activation: isomerization by the prolyl isomerase Pin1.

  Cell death and differentiation 20120101

• Searching for novel anti-myotonic agents: pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide.

  Neuromuscular disorders : NMD 20120101

• The effect of carnitine on Arabidopsis development and recovery in salt stress conditions.

  Planta 20120101

• Intramolecular C---H···O hydrogen-bond mediated stabilization of a cis-DPro imide-bond in a stereocontrolled heterochiral model peptide.

  Biopolymers 20120101

• The rice transcription factor IDEF1 directly binds to iron and other divalent metals for sensing cellular iron status.

  The Plant journal : for cell and molecular biology 20120101

• Experimental hyperprolinemia induces mild oxidative stress, metabolic changes, and tissue adaptation in rat liver.

  Journal of cellular biochemistry 20120101

• Proline substitutions and threonine pseudophosphorylation of the SH3 ligand of 18.5-kDa myelin basic protein decrease its affinity for the Fyn-SH3 domain and alter process development and protein localization in oligodendrocytes.

  Journal of neuroscience research 20120101

• Investigating diproline segments in proteins: occurrences, conformation and classification.

  Biopolymers 20120101

• Effects of ring contraction on the conformational preferences of α-substituted proline analogs.

  Biopolymers 20120101

• Exogenous ornithine is an effective precursor and the δ-ornithine amino transferase pathway contributes to proline accumulation under high N recycling in salt-stressed cashew leaves.

  Journal of plant physiology 20120101

• Biosynthesis of the nargenicin A1 pyrrole moiety from Nocardia sp. CS682.

  Applied microbiology and biotechnology 20120101

• Microtubule-associated protein 4 binds to actin filaments and modulates their properties.

  Journal of biochemistry 20120101

• Anticancer effects of a specific mixture of nutrients in the multidrug-resistant human uterine sarcoma MES-SA/Dx5 and the drug-sensitive MES-SA cell lines.

  Oncology reports 20120101

• Caveolin-1 hydrophobic segment peptides insertion into membrane mimetic systems: role of proline residue.

  Biochimica et biophysica acta 20120101

• In vitro anticancer activity of stachydrine isolated from Capparis decidua on prostate cancer cell lines.

  Natural product research 20120101

• Functional analysis of the human concentrative nucleoside transporter-1 variant hCNT1S546P provides insight into the sodium-binding pocket.

  American journal of physiology. Cell physiology 20120101

• The triple helical structure and stability of collagen model peptide with 4(S)-hydroxyprolyl-Pro-Gly units.

  Biopolymers 20120101

• Changes in the nature of phenolic deposits after re-warming as a result of melatonin pre-sowing treatment of Vigna radiata seeds.

  Journal of plant physiology 20120101

• Genetic diversity of influenza A(H1N1)2009 virus circulating during the season 2010-2011 in Spain.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20120101

• Six alkaloids inhibit secretion of IL-1α, TXB(2), ET-1 and E-selectin in LPS-induced endothelial cells.

  Immunological investigations 20120101

• L-proline dehydrogenases in hyperthermophilic archaea: distribution, function, structure, and application.

  Applied microbiology and biotechnology 20120101

• Understanding UV-driven metabolism in the hypersaline ciliate Fabrea salina.

  European biophysics journal : EBJ 20120101

• Brain superoxide anion formation in immature rats during seizures: protection by selected compounds.

  Experimental neurology 20120101

• Effect of heat stress on polyamine metabolism in proline-over-producing tobacco plants.

  Plant science : an international journal of experimental plant biology 20120101

• Phospholipases C and D modulate proline accumulation in Thellungiella halophila/salsuginea differently according to the severity of salt or hyperosmotic stress.

  Plant & cell physiology 20120101

• Quality parameters and antioxidant and antibacterial properties of some Mexican honeys.

  Journal of food science 20120101

• Boceprevir and telaprevir in the management of hepatitis C virus-infected patients.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120101

• Multiple roles of proline transport and metabolism in trypanosomatids.

  Frontiers in bioscience (Landmark edition) 20120101

• Substrate channeling in proline metabolism.

  Frontiers in bioscience (Landmark edition) 20120101

• The Na⁺/L-proline transporter PutP.

  Frontiers in bioscience (Landmark edition) 20120101

• Proline metabolism and cancer.

  Frontiers in bioscience (Landmark edition) 20120101

• [Boceprevir-benefit assessment by the Institute for Quality and Efficiency in Health Care (IQWiG) in accordance with § 35a SGB V (dosage evaluation)].

  Zeitschrift fur Gastroenterologie 20120101

• [Expert opinion on boceprevir- and telaprevir-based triple therapies of chronic hepatitis C].

  Zeitschrift fur Gastroenterologie 20120101

• New developments in HCV therapy.

  Journal of viral hepatitis 20120101

• Endophytic fungal association via gibberellins and indole acetic acid can improve plant growth under abiotic stress: an example of Paecilomyces formosus LHL10.

  BMC microbiology 20120101

• Effect of P to A mutation of the N-terminal residue adjacent to the Rgd motif on rhodostomin: importance of dynamics in integrin recognition.

  PloS one 20120101

• Boceprevir, telaprevir, and rilpivirine hydrochloride.

  Journal of the American Pharmacists Association : JAPhA 20120101

• The roles of intrinsic disorder in orchestrating the Wnt-pathway.

  Journal of biomolecular structure & dynamics 20120101

• [Victrelis and Incivek against hepatitis C: some promising options].

  Perspective infirmiere : revue officielle de l'Ordre des infirmieres et infirmiers du Quebec 20120101

• Antiviral strategies in hepatitis C virus infection.

  Journal of hepatology 20120101

• A review of drug interactions with boceprevir and telaprevir: implications for HIV and transplant patients.

  Annals of hepatology 20120101

• Treatment of chronic hepatitis C genotype 1 with triple therapy comprising telaprevir or boceprevir.

  Swiss medical weekly 20120101

• OneG: a computational tool for predicting cryptic intermediates in the unfolding kinetics of proteins under native conditions.

  PloS one 20120101

• Effect of substitution of proline-77 to aspartate on the light-driven proton release of bacteriorhodopsin.

  Photochemistry and photobiology 20120101

• Enhancement of the proline and nitric oxide synthetic pathway improves fermentation ability under multiple baking-associated stress conditions in industrial baker's yeast.

  Microbial cell factories 20120101

• Composition of pomegranate juice.

  Journal of AOAC International 20120101

• A novel N-terminal domain may dictate the glucose response of Mondo proteins.

  PloS one 20120101

• Advances in the treatment of hepatitis C virus infection.

  Topics in antiviral medicine 20120101

• Raw and fungal-treated olive-mill wastewater effects on selected parameters of lettuce (Lactuca sativa L.) growth--the role of proline.

  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20120101

• Proteome-wide analysis of single-nucleotide variations in the N-glycosylation sequon of human genes.

  PloS one 20120101

• Improved tolerance to various abiotic stresses in transgenic sweet potato (Ipomoea batatas) expressing spinach betaine aldehyde dehydrogenase.

  PloS one 20120101

• Biological effects of weak electromagnetic field on healthy and infected lime (Citrus aurantifolia) trees with phytoplasma.

  TheScientificWorldJournal 20120101

• Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix.

  Retrovirology 20120101

• Hypoallergenic mutants of the Timothy grass pollen allergen Phl p 5 generated by proline mutations.

  International archives of allergy and immunology 20120101

• Influence of a novel inhibitor (UM8190) of prolylcarboxypeptidase (PRCP) on appetite and thrombosis.

  Current medicinal chemistry 20120101

• Glutathione peroxidase 1 Pro198Leu polymorphism in Brazilian Alzheimer's disease patients: relations to the enzyme activity and to selenium status.

  Journal of nutrigenetics and nutrigenomics 20120101

• Metabolite adjustments in drought tolerant and sensitive soybean genotypes in response to water stress.

  PloS one 20120101

• Dimethylsulphopropionate (DMSP) and proline from the surface of the brown alga Fucus vesiculosus inhibit bacterial attachment.

  Biofouling 20120101

• [Efficacy of triple therapy in patients with chronic hepatitis C not treated and patients previously treated ineffectively].

  Przeglad epidemiologiczny 20120101

• [Effect of exogenous carbon monoxide donor hematin on seed germination and physiological characteristics of Cassia obtusifolia seedlings under NaCl stress].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120101

• An on-demand metalloprotease from psychro-tolerant Exiguobacterium undae Su-1, the activity and stability of which are controlled by the Ca2+ concentration.

  Bioscience, biotechnology, and biochemistry 20120101

• [The search of small molecules with antipsychotic activity on the background of neurotensin].

  Bioorganicheskaia khimiia 20120101

• Drosophila heat shock response requires the JNK pathway and phosphorylation of mixed lineage kinase at a conserved serine-proline motif.

  PloS one 20120101

• Investigation of the skin sensitizing properties of 5 osmolytic prodrugs in a weight-of-evidence assessment, employing in silico, in vivo, and read across analyses.

  International journal of toxicology 20120101

• Comparison of freezing tolerance, compatible solutes and polyamines in geographically diverse collections of Thellungiella sp. and Arabidopsis thaliana accessions.

  BMC plant biology 20120101

• Effects of exogenous proline and glycinebetaine on the salt tolerance of rice cultivars.

  Bioscience, biotechnology, and biochemistry 20120101

• Assaying proline hydroxylation in recombinant collagen variants by liquid chromatography-mass spectrometry.

  BMC biotechnology 20120101

• Mechanism of P-glycoprotein expression in the SGC7901 human gastric adenocarcinoma cell line induced by cyclooxygenase-2.

  Asian Pacific journal of cancer prevention : APJCP 20120101

• Differential responses of two broccoli (Brassica oleracea L. var Italica) cultivars to salinity and nutritional quality improvement.

  TheScientificWorldJournal 20120101

• Functional specialization in proline biosynthesis of melanoma.

  PloS one 20120101

• The p53 codon 72 PRO/PRO genotype may be associated with initial central visual field defects in caucasians with primary open angle glaucoma.

  PloS one 20120101

• Suppression of NF-κB reduces myocardial no-reflow.

  PloS one 20120101

• Inhibition of NF-κB prevents high glucose-induced proliferation and plasminogen activator inhibitor-1 expression in vascular smooth muscle cells.

  Experimental & molecular medicine 20111231

• Solvent and conformation dependence of amide I vibrations in peptides and proteins containing proline.

  The Journal of chemical physics 20111221

• Hepatitis C in 2011: A new standard of care and the race towards IFN-free therapy.

  Nature reviews. Gastroenterology & hepatology 20111220

• Asymmetric α alkylation of aldehydes: efficiency with elegance.

  Angewandte Chemie (International ed. in English) 20111216

• Steady-state kinetic mechanism of the proline:ubiquinone oxidoreductase activity of proline utilization A (PutA) from Escherichia coli.

  Archives of biochemistry and biophysics 20111215

• Radicals formed in N-acetylproline by electron attachment: electron spin resonance spectroscopy and computational studies.

  The journal of physical chemistry. B 20111215

• A native disulfide stabilizes non-native helical structures in partially folded states of equine β-lactoglobulin.

  Biochemistry 20111213

• Physiologically relevant oxidative degradation of oligo(proline) cross-linked polymeric scaffolds.

  Biomacromolecules 20111212

• [Side-effects of pegylated interferon plus ribavirin therapy with or without protease inhibitor direct acting antiviral agents during treatment of chronic hepatitis C virus infection].

  Orvosi hetilap 20111211

• Early improved and late defective cognition is reflected by dendritic spines in Tau.P301L mice.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20111207

• New HCV drugs trigger race for more tolerable therapies.

  Nature medicine 20111206

• UV-B and UV-C pre-treatments induce physiological changes and artemisinin biosynthesis in Artemisia annua L. - an antimalarial plant.

  Journal of photochemistry and photobiology. B, Biology 20111202

• The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport.

  British journal of pharmacology 20111201

• Brain pharmacokinetics of two prolyl oligopeptidase inhibitors, JTP-4819 and KYP-2047, in the rat.

  Basic & clinical pharmacology & toxicology 20111201

• Salt-induced modulation in inorganic nutrients, antioxidant enzymes, proline content and seed oil composition in safflower (Carthamus tinctorius L.).

  Journal of the science of food and agriculture 20111201

• Galectin-3 germline variant at position 191 enhances nuclear accumulation and activation of β-catenin in gastric cancer.

  Clinical & experimental metastasis 20111201

• The embryo rescue derived intergeneric hybrid between chrysanthemum and Ajania przewalskii shows enhanced cold tolerance.

  Plant cell reports 20111201

• MICALs in control of the cytoskeleton, exocytosis, and cell death.

  Cellular and molecular life sciences : CMLS 20111201

• The influence of the peptide bond on the conformation of amino acids: a theoretical and FT-IR matrix-isolation study of N-acetylproline.

  Biophysical chemistry 20111201

• Analysis of long-term persistence of resistance mutations within the hepatitis C virus NS3 protease after treatment with telaprevir or boceprevir.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20111201

• Cloning two P5CS genes from bioenergy sorghum and their expression profiles under abiotic stresses and MeJA treatment.

  Plant science : an international journal of experimental plant biology 20111201

• PrcR, a PucR-type transcriptional activator, is essential for proline utilization and mediates proline-responsive expression of the proline utilization operon putBCP in Bacillus subtilis.

  Microbiology (Reading, England) 20111201

• Biochemical effect of carbaryl on oxidative stress, antioxidant enzymes and osmolytes of cyanobacterium Calothrix brevissima.

  Bulletin of environmental contamination and toxicology 20111201

• High-resolution crystal structure of spectrin SH3 domain fused with a proline-rich peptide.

  Journal of biomolecular structure & dynamics 20111201

• Enhanced in vitro regeneration and change in photosynthetic pigments, biomass and proline content in Withania somnifera L. (Dunal) induced by copper and zinc ions.

  Plant physiology and biochemistry : PPB 20111201

• Boceprevir.

  Hepatology (Baltimore, Md.) 20111201

• Mislocalization and degradation of human P23H-rhodopsin-GFP in a knockin mouse model of retinitis pigmentosa.

  Investigative ophthalmology & visual science 20111201

• Telaprevir for the treatment of chronic hepatitis C infection.

  Expert review of anti-infective therapy 20111201

• Dynamic nuclear polarization at 9T using a novel 250 GHz gyrotron microwave source. 2003.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20111201

• Interspecific differences in tannin intakes of forest-dwelling rodents in the wild revealed by a new method using fecal proline content.

  Journal of chemical ecology 20111201

• A major advance in treating hepatitis C.

  The Johns Hopkins medical letter health after 50 20111201

• Direct-acting antiviral (DAA) actions in treatment-naïve patients.

  Clinics and research in hepatology and gastroenterology 20111201

• Antiviral activity of telaprevir and boceprevir for the treatment of hepatitis C virus infection in treatment-experienced patients.

  Clinics and research in hepatology and gastroenterology 20111201

• New hepatitis C regimen stimulates changes in therapy management.

  Managed care (Langhorne, Pa.) 20111201

• Semi-targeted analysis of metabolites using capillary-flow ion chromatography coupled to high-resolution mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20111130

• Challenges and opportunities for hepatitis C drug development in HIV-hepatitis C virus-co-infected patients.

  AIDS (London, England) 20111128

• String kernels and high-quality data set for improved prediction of kinked helices in α-helical membrane proteins.

  Journal of chemical information and modeling 20111128

• Efficient organocatalytic cross-aldol reaction between aliphatic aldehydes through their functional differentiation.

  Journal of the American Chemical Society 20111116

• Dopamine-depletion and increased α-synuclein load induce degeneration of cortical cholinergic fibers in mice.

  Journal of the neurological sciences 20111115

• MdVHP1 encodes an apple vacuolar H(+)-PPase and enhances stress tolerance in transgenic apple callus and tomato.

  Journal of plant physiology 20111115

• Identifying developmental toxicity pathways for a subset of ToxCast chemicals using human embryonic stem cells and metabolomics.

  Toxicology and applied pharmacology 20111115

• Identification of biomarkers for melamine-induced nephrolithiasis in young children based on ultra high performance liquid chromatography coupled to time-of-flight mass spectrometry (U-HPLC-Q-TOF/MS).

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115

• Solid-phase synthesis of smac peptidomimetics incorporating triazoloprolines and biarylalanines.

  ACS combinatorial science 20111114

• Protease inhibitors for treatment of genotype 1 hepatitis C virus infection.

  BMJ (Clinical research ed.) 20111110

• Multivalent binding of formin-binding protein 21 (FBP21)-tandem-WW domains fosters protein recognition in the pre-spliceosome.

  The Journal of biological chemistry 20111104

• Crystal structures of protein glutaminase and its pro forms converted into enzyme-substrate complex.

  The Journal of biological chemistry 20111104

• An ester enolate-Claisen rearrangement route to substituted 4-alkylideneprolines. studies toward a definitive structural revision of lucentamycin A.

  The Journal of organic chemistry 20111104

• Photochemically induced radical transformation of C(sp3)-H bonds to C(sp3)-CN bonds.

  Organic letters 20111104

• Enhanced expression of AtNHX1, in transgenic groundnut (Arachis hypogaea L.) improves salt and drought tolerence.

  Molecular biotechnology 20111101

• Combining factors on protein and gene level to predict radioresponse in head and neck cancer cell lines.

  Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20111101

• Introduction of Pro and its analogues in the conserved P1' position of trypsin inhibitor SFTI-1 retains its inhibitory activity.

  Protein and peptide letters 20111101

• Inhibitory potential of tea polyphenolics and influence of extraction time against Helicobacter pylori and lack of inhibition of beneficial lactic acid bacteria.

  Journal of medicinal food 20111101

• MusaDHN-1, a novel multiple stress-inducible SK(3)-type dehydrin gene, contributes affirmatively to drought- and salt-stress tolerance in banana.

  Planta 20111101

• Osmolyte effects on protein stability and solubility: a balancing act between backbone and side-chains.

  Biophysical chemistry 20111101

• A proline rich acidic protein PRAP identified from uterine luminal fluid of estrous mice is able to enhance the estrogen responsiveness of Ishikawa cells.

  Journal of cellular biochemistry 20111101

• Overexpression of the trehalose-6-phosphate synthase gene OsTPS1 enhances abiotic stress tolerance in rice.

  Planta 20111101

• ZmMKK4 regulates osmotic stress through reactive oxygen species scavenging in transgenic tobacco.

  Plant cell reports 20111101

• New treatments for chronic hepatitis C virus infection.

  Medecine et maladies infectieuses 20111101

• Future of hepatitis C therapy: development of direct-acting antivirals.

  Current opinion in HIV and AIDS 20111101

• 28-Homobrassinolide mitigates boron induced toxicity through enhanced antioxidant system in Vigna radiata plants.

  Chemosphere 20111101

• Oligopeptide cyclophilin inhibitors: a reassessment.

  European journal of medicinal chemistry 20111101

• Severe osteogenesis imperfecta caused by a small in-frame deletion in CRTAP.

  American journal of medical genetics. Part A 20111101

• L-Proline anchored multicomponent synthesis of novel pyrido[2,3-a]carbazoles; investigation of in vitro antimicrobial, antioxidant, cytotoxicity and structure activity relationship studies.

  European journal of medicinal chemistry 20111101

• Conserved proline-rich region of Ebola virus matrix protein VP40 is essential for plasma membrane targeting and virus-like particle release.

  The Journal of infectious diseases 20111101

• Down-regulation of matrix metalloproteinase-9 by pyrrolidine dithiocarbamate prevented retinal ganglion cell death after transection of optic nerve in rats.

  Current eye research 20111101

• Identification and expression analysis of CBF/DREB1 and COR15 genes in mutants of Brassica oleracea var. botrytis with enhanced proline production and frost resistance.

  Plant physiology and biochemistry : PPB 20111101

• Variation in salinity tolerance of four lowland genotypes of quinoa (Chenopodium quinoa Willd.) as assessed by growth, physiological traits, and sodium transporter gene expression.

  Plant physiology and biochemistry : PPB 20111101

• Directly acting antivirals for hepatitis C and antiretrovirals: potential for drug-drug interactions.

  Current opinion in HIV and AIDS 20111101

• The Muenke syndrome mutation (FgfR3P244R) causes cranial base shortening associated with growth plate dysfunction and premature perichondrial ossification in murine basicranial synchondroses.

  Developmental dynamics : an official publication of the American Association of Anatomists 20111101

• Formulary management of the protease inhibitors boceprevir and telaprevir for chronic hepatitis C virus.

  Journal of managed care pharmacy : JMCP 20111101

• The expanding role of the pharmacist in the management of hepatitis C infection.

  Journal of managed care pharmacy : JMCP 20111101

• Extracellular matrix-derived tripeptide proline-glycine-proline inhibits keratinocyte proliferation and migration.

  Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20111101

• Promysalin, a salicylate-containing Pseudomonas putida antibiotic, promotes surface colonization and selectively targets other Pseudomonas.

  Chemistry & biology 20111028

• Enantioselective organocatalytic Friedel-Crafts alkylation reaction of indoles with 5-hydroxyfuran-2(5H)-one: access to chiral γ-lactones and γ-lactams via a Ugi 4-center 3-component reaction.

  The Journal of organic chemistry 20111021

• Dissecting the functions of conserved prolines within transmembrane helices of the D2 dopamine receptor.

  ACS chemical biology 20111021

• Indirect repression by Bacillus subtilis CodY via displacement of the activator of the proline utilization operon.

  Journal of molecular biology 20111021

• Chiral phosphoproline-catalyzed asymmetric Michael addition of ketones to nitroolefins: an experimental and theoretical study.

  Organic & biomolecular chemistry 20111021

• N-Prolinylanthranilamide pseudopeptides as bifunctional organocatalysts for asymmetric aldol reactions.

  Organic letters 20111021

• Enamine carboxylates as stereodetermining intermediates in prolinate catalysis.

  Organic letters 20111021

• Proteomic identification of specifically carbonylated brain proteins in APP(NLh)/APP(NLh) × PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice model of Alzheimer disease as a function of age.

  Journal of proteomics 20111019

• New insight into marine alkaloid metabolic pathways: revisiting oroidin biosynthesis.

  Chembiochem : a European journal of chemical biology 20111017

• Influence of over-expression of cytosolic aspartate aminotransferase on amino acid metabolism and defence responses against Botrytis cinerea infection in Arabidopsis thaliana.

  Journal of plant physiology 20111015

• Labelless impedance immunosensor based on polypyrrole-pyrolecarboxylic acid copolymer for hCG detection.

  Talanta 20111015

• Structural impact of proline-directed pseudophosphorylation at AT8, AT100, and PHF1 epitopes on 441-residue tau.

  Journal of the American Chemical Society 20111012

• Proline-based reduced dipeptides as recyclable and highly enantioselective organocatalysts for asymmetric Michael addition.

  Organic & biomolecular chemistry 20111007

• Organocatalytic asymmetric domino aza-Michael-Mannich reaction: synthesis of tetrahydroimidazopyrimidine derivatives.

  The Journal of organic chemistry 20111007

• Proline-based P,O ligand/iridium complexes as highly selective catalysts: asymmetric hydrogenation of trisubstituted alkenes.

  Angewandte Chemie (International ed. in English) 20111004

• Combined expression of tau and the Harlequin mouse mutation leads to increased mitochondrial dysfunction, tau pathology and neurodegeneration.

  Neurobiology of aging 20111001

• Heavy metal-induced physiological alterations and oxidative stress in the moss Brachythecium piligerum chad.

  Environmental toxicology 20111001

• Inhibition of pro-inflammatory mediators: role of Bacopa monniera (L.) Wettst.

  Inflammopharmacology 20111001

• The effect of Semax and its C-end peptide PGP on the morphology and proliferative activity of rat brain cells during experimental ischemia: a pilot study.

  Journal of molecular neuroscience : MN 20111001

• DFT and MP2 investigations of L-proline and its hydrated complexes.

  Journal of molecular modeling 20111001

• Sequence analysis of PAX9, MSX1 and AXIN2 genes in a Chinese oligodontia family.

  Archives of oral biology 20111001

• Systematic parameter optimization of a Me(2)SO- and serum-free cryopreservation protocol for human mesenchymal stem cells.

  Cryobiology 20111001

• Pro12Ala polymorphism in human peroxisome proliferator activated receptor gamma is associated with hyperlipidaemia in obstructive sleep apnoea hypopnoea syndrome.

  The Journal of laryngology and otology 20111001

• Bezafibrate prevents palmitate-induced apoptosis in osteoblastic MC3T3-E1 cells through the NF-κB signaling pathway.

  International journal of molecular medicine 20111001

• Importance of CH/π hydrogen bonds in recognition of the core motif in proline-recognition domains: an ab initio fragment molecular orbital study.

  Journal of computational chemistry 20111001

• Functional splicing assay of DSPP mutations in hereditary dentin defects.

  Oral diseases 20111001

• Pattern of solutes accumulated during leaf osmotic adjustment as related to duration of water deficit for wheat at the reproductive stage.

  Plant physiology and biochemistry : PPB 20111001

• Enzymes of the ornithine-glutamate-proline pathway in the sheep abomasal nematode parasites Haemonchus contortus and Teladorsagia circumcincta.

  Experimental parasitology 20111001

• Differential physiological and biochemical responses of two cyanobacteria Nostoc muscorum and Phormidium foveolarum against oxyfluorfen and UV-B radiation.

  Ecotoxicology and environmental safety 20111001

• Analysis by virus induced gene silencing of the expression of two proline biosynthetic pathway genes in Nicotiana benthamiana under stress conditions.

  Plant physiology and biochemistry : PPB 20111001

• Discovery of BI 99179, a potent and selective inhibitor of type I fatty acid synthase with central exposure.

  Bioorganic & medicinal chemistry letters 20111001

• Arabidopsis LOS5/ABA3 overexpression in transgenic tobacco (Nicotiana tabacum cv. Xanthi-nc) results in enhanced drought tolerance.

  Plant science : an international journal of experimental plant biology 20111001

• An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases.

  Hepatology (Baltimore, Md.) 20111001

• Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors.

  Bioorganic & medicinal chemistry 20111001

• Tandem mass spectrometric characterization of thiol peptides modified by the chemoselective cationic sulfhydryl reagent (4-iodobutyl)triphenylphosphonium--effects of a cationic thiol derivatization on peptide fragmentation.

  Journal of the American Society for Mass Spectrometry 20111001

• Antiviral drugs for viruses other than human immunodeficiency virus.

  Mayo Clinic proceedings 20111001

• Association of serum lipid/lipoprotein with Pro12Ala polymorphism in PPAR-γ2 among Chinese nonagenarians/centenarians.

  Archives of medical research 20111001

• Boceprevir.

  Drugs of today (Barcelona, Spain : 1998) 20111001

• [Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].

  Guang pu xue yu guang pu fen xi = Guang pu 20111001

• Targeting of a common receptor shared by CXCL8 and N-Ac-PGP as a therapeutic strategy to alleviate chronic neutrophilic lung diseases.

  European journal of pharmacology 20110930

• The TβR-I pre-helix extension is structurally ordered in the unbound form and its flanking prolines are essential for binding.

  Journal of molecular biology 20110930

• Increased hydrophobicity and decreased backbone flexibility explain the lower solubility of a cataract-linked mutant of γD-crystallin.

  Journal of molecular biology 20110930

• [New triple therapy in chronic hepatitis C. Increased patient chances].

  MMW Fortschritte der Medizin 20110929

• Rapid photoassisted access to N,O,S-polyheterocycles with benzoazocine and hydroquinoline cores: intramolecular cycloadditions of photogenerated azaxylylenes.

  Angewandte Chemie (International ed. in English) 20110926

• Systematic identification of tubulin-interacting fragments of the microtubule-associated protein Tau leads to a highly efficient promoter of microtubule assembly.

  The Journal of biological chemistry 20110923

• Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK).

  The Journal of biological chemistry 20110923

• Production of anticancer polyenes through precursor-directed biosynthesis.

  Organic & biomolecular chemistry 20110921

• Valence anions of N-acetylproline in the gas phase: computational and anion photoelectron spectroscopic studies.

  The Journal of chemical physics 20110921

• Proline in transmembrane domain of type II protein DPP-IV governs its translocation behavior through endoplasmic reticulum.

  Biochemistry 20110920

• Identification of proline residues in or near the transmembrane helices of the human breast cancer resistance protein (BCRP/ABCG2) that are important for transport activity and substrate specificity.

  Biochemistry 20110920

• L-Proline/CoCl2-catalyzed highly diastereo- and enantioselective direct aldol reactions.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110919

• Proline-based chiral stationary phases: a molecular dynamics study of the interfacial structure.

  Journal of chromatography. A 20110916

• Expression and substrate specificity of betaine/proline transporters suggest a novel choline transport mechanism in sugar beet.

  Journal of plant physiology 20110915

• Inhibition of prolyl oligopeptidase by KYP-2047 fails to increase the extracellular neurotensin and substance P levels in rat striatum.

  Neuroscience letters 20110915

• Betaines in fruits of Citrus genus plants.

  Journal of agricultural and food chemistry 20110914

• Substrate-mediated fidelity mechanism ensures accurate decoding of proline codons.

  The Journal of biological chemistry 20110909

• L-Proline promoted fluorescent sensor for Mg2+ detection in a multicomponent sensory system.

  Chemical communications (Cambridge, England) 20110907

• Group II/III metabotropic glutamate receptors exert endogenous activity-dependent modulation of TRPV1 receptors on peripheral nociceptors.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20110907

• [New treatments for hepatitis C, which targets, what timeline?].

  Revue medicale suisse 20110907

• Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface.

  Journal of molecular biology 20110902

• Calcineurin selectively docks with the dynamin Ixb splice variant to regulate activity-dependent bulk endocytosis.

  The Journal of biological chemistry 20110902

• Biomimetic organocatalytic asymmetric synthesis of 2-substituted piperidine-type alkaloids and their analogues.

  Organic letters 20110902

• Plasma CD93 concentration is a potential novel biomarker for coronary artery disease.

  Journal of internal medicine 20110901

• HIF1A P582S gene association with endurance training responses in young women.

  European journal of applied physiology 20110901

• Stabilization of triple-helical structures of collagen peptides containing a Hyp-Thr-Gly, Hyp-Val-Gly, or Hyp-Ser-Gly sequence.

  Biopolymers 20110901

• Transgenic expression of TaMYB2A confers enhanced tolerance to multiple abiotic stresses in Arabidopsis.

  Functional & integrative genomics 20110901

• Tobacco leaves and roots differ in the expression of proline metabolism-related genes in the course of drought stress and subsequent recovery.

  Journal of plant physiology 20110901

• Direct observations of conformational distributions of intrinsically disordered p53 peptides using UV Raman and explicit solvent simulations.

  The journal of physical chemistry. A 20110901

• Antibacterial peptides derived from caprine whey proteins, by digestion with human gastrointestinal juice.

  The British journal of nutrition 20110901

• A cotton group C MAP kinase gene, GhMPK2, positively regulates salt and drought tolerance in tobacco.

  Plant molecular biology 20110901

• An IκBα phosphorylation inhibitor induces heme oxygenase-1(HO-1) expression through the activation of reactive oxygen species (ROS)-Nrf2-ARE signaling and ROS-PI3K/Akt signaling in an NF-κB-independent mechanism.

  Cellular signalling 20110901

• Behavioral and neurochemical effects of proline.

  Metabolic brain disease 20110901

• Evidence for association of hyperprolinemia with schizophrenia and a measure of clinical outcome.

  Schizophrenia research 20110901

• Differential efficacy of protease inhibitors against HCV genotypes 2a, 3a, 5a, and 6a NS3/4A protease recombinant viruses.

  Gastroenterology 20110901

• Proline betaine and its biotransformation products in fasting urine samples are potential biomarkers of habitual citrus fruit consumption.

  The British journal of nutrition 20110901

• Essential role of tissue-specific proline synthesis and catabolism in growth and redox balance at low water potential.

  Plant physiology 20110901

• Synthesis and diuretic activities of pseudoproline-containing analogues of the insect kinin core pentapeptide.

  Journal of peptide science : an official publication of the European Peptide Society 20110901

• Boceprevir: a protease inhibitor for the treatment of chronic hepatitis C.

  The Annals of pharmacotherapy 20110901

• Some physiological and biochemical responses to nickel in salicylic acid applied chickpea (Cicer arietinum L.) seedlings.

  Acta biologica Hungarica 20110901

• Emerging therapies in hepatitis C: dawn of the era of the direct-acting antivirals.

  Gastroenterology clinics of North America 20110901

• Facial skin-lightening benefits of the tetrapeptide Pro-Lys-Glu-Lys on subjects with skin types V-VI living in South Africa.

  Journal of cosmetic dermatology 20110901

• Will direct-acting antivirals make a difference in HIV-HCV coinfected patients?

  Expert review of anti-infective therapy 20110901

• Nickel-induced changes in lipid peroxidation, antioxidative enzymes, and metal accumulation in Lemna gibba.

  International journal of phytoremediation 20110901

• Protease inhibitors in hepatitis C: from chronic disease to cure.

  Irish medical journal 20110901

• Stable-isotope labeling with amino acids in nematodes.

  Nature methods 20110828

• Phylogeny-guided isolation of ethyl tumonoate A from the marine cyanobacterium cf. Oscillatoria margaritifera.

  Journal of natural products 20110826

• Insights into the reaction mechanism of the prolyl-acyl carrier protein oxidase involved in anatoxin-a and homoanatoxin-a biosynthesis.

  Biochemistry 20110823

• Thiourea/proline derivative-catalyzed synthesis of tetrahydrofuran derivatives: a mechanistic view.

  The Journal of organic chemistry 20110819

• Kinetic profiling of prolinate-catalyzed α-amination of aldehydes.

  Organic letters 20110819

• Prolines in βA-sheet of neural cadherin act as a switch to control the dynamics of the equilibrium between monomer and dimer.

  Biochemistry 20110816

• Ruthenium-catalysed synthesis of fluorinated bicyclic amino esters through tandem carbene addition/cyclopropanation of enynes.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110816

• Steric effects on the enantiodiscrimination of diproline chiral stationary phases in the resolution of racemic compounds.

  Journal of chromatography. A 20110812

• Dynamic one-pot three-component catalytic asymmetric transformation by combination of hydrogen-bond-donating and amine catalysts.

  Angewandte Chemie (International ed. in English) 20110808

• Structure analysis of an amyloid-forming model peptide by a systematic glycine and proline scan.

  Biomacromolecules 20110808

• An L-proline functionalized metallo-organic triangle as size-selective homogeneous catalyst for asymmetry catalyzing aldol reactions.

  Chemical communications (Cambridge, England) 20110807

• Arg149 is involved in switching the low affinity, open state of the binding protein AfProX into its high affinity, closed state.

  Journal of molecular biology 20110805

• Prolyl oligopeptidase induces angiogenesis both in vitro and in vivo in a novel regulatory manner.

  British journal of pharmacology 20110801

• Inhibition of NF-κB signaling commits resveratrol-treated medulloblastoma cells to apoptosis without neuronal differentiation.

  Journal of neuro-oncology 20110801

• Development of a genetic system for the moderately halophilic bacterium Halobacillus halophilus: generation and characterization of mutants defect in the production of the compatible solute proline.

  Environmental microbiology 20110801

• Physiological mechanisms underlying OsNAC5-dependent tolerance of rice plants to abiotic stress.

  Planta 20110801

• p53 codon 72 polymorphism in patients with gastric and colorectal cancer in a Korean population.

  Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20110801

• ZmMKK4, a novel group C mitogen-activated protein kinase kinase in maize (Zea mays), confers salt and cold tolerance in transgenic Arabidopsis.

  Plant, cell & environment 20110801

• Practical access to the proline analogs (S,S,S)- and (R,R,R)-2-methyloctahydroindole-2-carboxylic acids by HPLC enantioseparation.

  Chirality 20110801

• A mitochondrial GABA permease connects the GABA shunt and the TCA cycle, and is essential for normal carbon metabolism.

  The Plant journal : for cell and molecular biology 20110801

• Overexpression of a Harpin-encoding gene hrf1 in rice enhances drought tolerance.

  Journal of experimental botany 20110801

• Conformational constraints in angiotensin IV to probe the role of Tyr², Pro⁵ and Phe⁶.

  Journal of peptide science : an official publication of the European Peptide Society 20110801

• A straightforward route to enantiopure 2-substituted-3,4-dehydro-β-proline via ring closing metathesis.

  Amino acids 20110801

• Synthesis and structural study of highly constrained hybrid cyclobutane-proline γ,γ-peptides.

  Amino acids 20110801

• The RabGAP proteins Gyp5p and Gyl1p recruit the BAR domain protein Rvs167p for polarized exocytosis.

  Traffic (Copenhagen, Denmark) 20110801

• The dominant glutamic acid metabolic flux to produce γ-amino butyric acid over proline in Nicotiana tabacum leaves under water stress relates to its significant role in antioxidant activity.

  Journal of integrative plant biology 20110801

• Elucidation of physiological and biochemical mechanisms of an endemic halophyte Centaurea tuzgoluensis under salt stress.

  Plant physiology and biochemistry : PPB 20110801

• Proline repeats, in cis- and trans-positions, confer protection against the toxicity of misfolded proteins in a mammalian cellular model.

  Neuroscience research 20110801

• Directly acting antivirals against hepatitis C virus.

  The Journal of antimicrobial chemotherapy 20110801

• Proline accumulation is inhibitory to Arabidopsis seedlings during heat stress.

  Plant physiology 20110801

• Elevation of free proline and proline-rich protein levels by simultaneous manipulations of proline biosynthesis and degradation in plants.

  Plant science : an international journal of experimental plant biology 20110801

• 15-Deoxy-Δ(12,14)-prostaglandin J(2) interferes inducible synthesis of prostaglandins E(2) and F(2α) that suppress subsequent adipogenesis program in cultured preadipocytes.

  Prostaglandins & other lipid mediators 20110801

• Proline dehydrogenase is a positive regulator of cell death in different kingdoms.

  Plant signaling & behavior 20110801

• HCV protease inhibitors bring new options for patients.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110801

• Going viral.

  Scientific American 20110801

• An overview of emerging therapies for the treatment of chronic hepatitis C.

  Clinics in liver disease 20110801

• Boceprevir: a user's guide.

  Clinics in liver disease 20110801

• Second-wave protease inhibitors: choosing an heir.

  Clinics in liver disease 20110801

• [Determination of underivatized glycine and proline in vinegar turtle shell by HPLC-ELSD].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110801

• Effects of Pro-Gly-Pro tripeptide on the dopamine system.

  Bulletin of experimental biology and medicine 20110801

• Backbone cyclic peptide inhibitors of protein kinase B (PKB/Akt).

  Journal of medicinal chemistry 20110728

• Imidazolium ylides from a conjugate addition-proton transfer route and their cycloaddition reactions.

  Chemical communications (Cambridge, England) 20110728

• Telaprevir (Incivek) and boceprevir (Victrelis) for chronic hepatitis C.

  The Medical letter on drugs and therapeutics 20110725

• [Studies with boceprevir].

  MMW Fortschritte der Medizin 20110721

• [A new era in therapy of hepatitis C: 'the therapy can now be individualized' (interview by Dr. med. Dirk Einecke)].

  MMW Fortschritte der Medizin 20110721

• An advance in proline ligation.

  Journal of the American Chemical Society 20110720

• Importance of ring puckering versus interstrand hydrogen bonds for the conformational stability of collagen.

  Angewandte Chemie (International ed. in English) 20110718

• Transformation of tomato with a bacterial codA gene enhances tolerance to salt and water stresses.

  Journal of plant physiology 20110715

• Role of stereoelectronic features of imine and enamine in (S)-proline catalyzed Mannich reaction of acetaldehyde: an in silico study.

  Journal of computational chemistry 20110715

• Activation of CXCR2 by extracellular matrix degradation product acetylated Pro-Gly-Pro has therapeutic effects against sepsis.

  American journal of respiratory and critical care medicine 20110715

• Nuclear factor-kappaB (NF-kappaB) p65 interacts with Stat5b in growth plate chondrocytes and mediates the effects of growth hormone on chondrogenesis and on the expression of insulin-like growth factor-1 and bone morphogenetic protein-2.

  The Journal of biological chemistry 20110715

• Functional characterization of the P1059L mutation in the inositol 1,4,5-trisphosphate receptor type 1 identified in a Japanese SCA15 family.

  Biochemical and biophysical research communications 20110715

• Boceprevir for chronic HCV genotype 1 infection.

  The New England journal of medicine 20110714

• Boceprevir for chronic HCV genotype 1 infection.

  The New England journal of medicine 20110714

• Biosynthetic chlorination of the piperazate residue in kutzneride biosynthesis by KthP.

  Biochemistry 20110712

• New Merck and Vertex drugs raise standard of care in hepatitis C.

  Nature biotechnology 20110711

• The approach of conformational chimeras to model the role of proline-containing helices on GPCR mobility: the fertile case of Cys-LTR1.

  ChemMedChem 20110704

• Fragment condensation of C-terminal pseudoproline peptides without racemization on the solid phase.

  Angewandte Chemie (International ed. in English) 20110704

• Hepatitis C virus resistance to protease inhibitors.

  Journal of hepatology 20110701

• Evolution of nuclear retinoic acid receptor alpha (RARα) phosphorylation sites. Serine gain provides fine-tuned regulation.

  Molecular biology and evolution 20110701

• CLRN1 mutations cause nonsyndromic retinitis pigmentosa.

  Ophthalmology 20110701

• Azospirillum and arbuscular mycorrhizal colonization enhance rice growth and physiological traits under well-watered and drought conditions.

  Journal of plant physiology 20110701

• The effects of an ideal beta-turn on beta-2 microglobulin fold stability.

  Journal of biochemistry 20110701

• Isolation and partial characterization of the Chlamydomonas reinhardtii γ-glutamyl kinase.

  Journal of bioscience and bioengineering 20110701

• Unexpected property of ectoine synthase and its application for synthesis of the engineered compatible solute ADPC.

  Applied microbiology and biotechnology 20110701

• Application of L-proline derivatives as chiral shift reagents for enantiomeric recognition of carboxylic acids.

  Chirality 20110701

• The P-selectin gene Pro715 allele and low levels of soluble P-selectin are associated with reduced P2Y12 adenosine diphosphate receptor reactivity in clopidogrel-treated patients.

  Atherosclerosis 20110701

• Role of reactive oxygen species and proline cycle in anthraquinone accumulation in Rubia tinctorum cell suspension cultures subjected to methyl jasmonate elicitation.

  Plant physiology and biochemistry : PPB 20110701

• Mechanisms of amyloid fibril formation--focus on domain-swapping.

  The FEBS journal 20110701

• How to remain nonfolded and pliable: the linkers in modular α-amylases as a case study.

  The FEBS journal 20110701

• The SIGMAR1 gene is associated with a risk of schizophrenia and activation of the prefrontal cortex.

  Progress in neuro-psychopharmacology & biological psychiatry 20110701

• Response to copper and sodium chloride excess in Spirulina sp. (cyanobacteria).

  Bulletin of environmental contamination and toxicology 20110701

• Epibrassinolide ameliorates Cr (VI) stress via influencing the levels of indole-3-acetic acid, abscisic acid, polyamines and antioxidant system of radish seedlings.

  Chemosphere 20110701

• TMKink: a method to predict transmembrane helix kinks.

  Protein science : a publication of the Protein Society 20110701

• Identification of regions responsible for heparin-induced amyloidogenesis of human serum amyloid A using its fragment peptides.

  Archives of biochemistry and biophysics 20110701

• Proline-rich antimicrobial peptides: converging to a non-lytic mechanism of action.

  Cellular and molecular life sciences : CMLS 20110701

• Effects of osmotic pretreatments on oxidative stress, antioxidant profiles and cryopreservation of olive somatic embryos.

  Plant science : an international journal of experimental plant biology 20110701

• CIPK7 is involved in cold response by interacting with CBL1 in Arabidopsis thaliana.

  Plant science : an international journal of experimental plant biology 20110701

• A nonpeptidic reverse-turn scaffold stabilized by urea-based dual intramolecular hydrogen bonding.

  Organic letters 20110701

• Soluble tau species, not neurofibrillary aggregates, disrupt neural system integration in a tau transgenic model.

  Journal of neuropathology and experimental neurology 20110701

• Physiology and proteomics of drought stress acclimation in sunflower (Helianthus annuus L.).

  Plant biology (Stuttgart, Germany) 20110701

• Two drugs approved for chronic hepatitis C infection.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110701

• Antimicrobial proline-rich peptides from the hemolymph of marine snail Rapana venosa.

  Peptides 20110701

• Cytotoxic effect of eugenol on the expression of molecular markers related to the osteogenic differentiation of human dental pulp cells.

  Odontology 20110701

• Telaprevir, boceprevir, cytochrome P450 and immunosuppressive agents--a potentially lethal cocktail.

  Hepatology (Baltimore, Md.) 20110701

• Ab initio calculations of proline vibrations with and without water: consequences on the infrared spectra of proline-rich proteins.

  Applied spectroscopy 20110701

• Inflammatory effects of blood leukocytes: association with vascular function in neuropeptide Y proline 7-genotyped type 2 diabetes patients.

  Diabetes & vascular disease research 20110701

• Interconversion of functional motions between mesophilic and thermophilic adenylate kinases.

  PLoS computational biology 20110701

• Repeated freeze-thawing of bone tissue affects Raman bone quality measurements.

  Journal of biomedical optics 20110701

• Permeability of the blood-brain barrier for dilept and its active metabolite.

  Bulletin of experimental biology and medicine 20110701

• Tunable pKa values and the basis of opposite charge selectivities in nicotinic-type receptors.

  Nature 20110623

• Direct aldol reactions catalyzed by a heterogeneous guanidinium salt/proline system under solvent-free conditions.

  Organic letters 20110617

• Prolyl oligopeptidase participates in cell cycle progression in a human neuroblastoma cell line.

  Biochemical and biophysical research communications 20110617

• O-glycosylated cell wall proteins are essential in root hair growth.

  Science (New York, N.Y.) 20110617

• Part 3: Design and synthesis of proline-derived α2δ ligands.

  Bioorganic & medicinal chemistry letters 20110615

• Well-defined homopolypeptides, copolypeptides, and hybrids of poly(l-proline).

  Biomacromolecules 20110613

• Introduction: a smouldering public-health crisis.

  Nature 20110608

• Therapeutics: new drugs hit the target.

  Nature 20110608

• Perspective: miles to go before we sleep.

  Nature 20110608

• Self-inclusion of proline-functionalised calix[4]arene leads to hydrogelation.

  Chemical communications (Cambridge, England) 20110607

• Recognition and ordering at surfaces: the importance of handedness and footedness.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20110606

• Prediction of variability in CYP3A4 induction using a combined 1H NMR metabonomics and targeted UPLC-MS approach.

  Journal of proteome research 20110603

• Quantum mechanical origin of the conformational preferences of 4-thiaproline and its S-oxides.

  Amino acids 20110601

• Exogenous proline application reduces phytotoxic effects of selenium by minimising oxidative stress and improves growth in bean (Phaseolus vulgaris L.) seedlings.

  Biological trace element research 20110601

• Comparing the structural properties of human and rat islet amyloid polypeptide by MD computer simulations.

  Biophysical chemistry 20110601

• Programmed hypertension in rats treated with a NF-κB inhibitor during nephrogenesis: renal mechanisms.

  Hypertension research : official journal of the Japanese Society of Hypertension 20110601

• Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and disruption of a distant poly-(L-proline) II helix.

  Chemical senses 20110601

• The amino acid transporter SNAT2 mediates L-proline-induced differentiation of ES cells.

  American journal of physiology. Cell physiology 20110601

• Normalization of proliferation and tight junction formation in bladder epithelial cells from patients with interstitial cystitis/painful bladder syndrome by d-proline and d-pipecolic acid derivatives of antiproliferative factor.

  Chemical biology & drug design 20110601

• Proteomic and metabolomic analysis of H2O2-induced premature senescent human mesenchymal stem cells.

  Experimental gerontology 20110601

• Effect of radioprotective agents in sporulation medium on Bacillus subtilis spore resistance to hydrogen peroxide, wet heat and germicidal and environmentally relevant UV radiation.

  Journal of applied microbiology 20110601

• Nuclear import of early growth response-1 involves importin-7 and the novel nuclear localization signal serine-proline-serine.

  The international journal of biochemistry & cell biology 20110601

• Characterization of an omega-class glutathione S-transferase in the stress response of the silkmoth.

  Insect molecular biology 20110601

• An Arabidopsis mutant disrupted in ASN2 encoding asparagine synthetase 2 exhibits low salt stress tolerance.

  Plant physiology and biochemistry : PPB 20110601

• Defect in proline synthesis: pyrroline-5-carboxylate reductase 1 deficiency leads to a complex clinical phenotype with collagen and elastin abnormalities.

  Journal of inherited metabolic disease 20110601

• Leukotriene A4 hydrolase: an anti-inflammatory role for a proinflammatory enzyme.

  Thorax 20110601

• Role of antioxidants on Na(+),K (+)-ATPase activity and gene expression in cerebral cortex of hyperprolinemic rats.

  Metabolic brain disease 20110601

• Determination of betaines in vegetable oils by capillary electrophoresis tandem mass spectrometry--application to the detection of olive oil adulteration with seed oils.

  Electrophoresis 20110601

• Distributive justice and the arrival of direct-acting antivirals: who should be first in line?

  Hepatology (Baltimore, Md.) 20110601

• Drought, metabolites, and Arabidopsis natural variation: a promising combination for understanding adaptation to water-limited environments.

  Current opinion in plant biology 20110601

• A multiple stress-responsive gene ERD15 from Solanum pennellii confers stress tolerance in tobacco.

  Plant & cell physiology 20110601

• Molecular simulations predict novel collagen conformations during cross-link loading.

  Matrix biology : journal of the International Society for Matrix Biology 20110601

• Release of growth factors by neuronal precursor cells as a treatment for diseases with tau pathology.

  Archives italiennes de biologie 20110601

• In vivo and in vitro antitumor effects of nutrient mixture in murine leukemia cell line P-388.

  Experimental oncology 20110601

• FDA Advisory Committee reviews safety of boceprevir.

  AIDS patient care and STDs 20110601

• Towards understanding the tandem mass spectra of protonated oligopeptides. 2: The proline effect in collision-induced dissociation of protonated Ala-Ala-Xxx-Pro-Ala (Xxx = Ala, Ser, Leu, Val, Phe, and Trp).

  Journal of the American Society for Mass Spectrometry 20110601

• Prolyl isomerases show low sequence specificity toward the residue following the proline.

  Biochemistry 20110531

• [New therapeutic options in chronic hepatitis C virus infection].

  Orvosi hetilap 20110529

• Stereocontrol in proline-catalyzed asymmetric amination: a comparative assessment of the role of enamine carboxylic acid and enamine carboxylate.

  Chemical communications (Cambridge, England) 20110528

• Isolation and structural elucidation of proline-containing cyclopentapeptides from an endolichenic Xylaria sp.

  Journal of natural products 20110527

• Knoevenagel reaction in [MMIm][MSO₄]: synthesis of coumarins.

  Molecules (Basel, Switzerland) 20110527

• Proline 68 enhances photoisomerization yield in photoactive yellow protein.

  The journal of physical chemistry. B 20110526

• Synthesis of conformationally constrained 5-fluoro- and 5-hydroxymethanopyrrolidines. Ring-puckered mimics of gauche- and anti-3-fluoro- and 3-hydroxypyrrolidines.

  The Journal of organic chemistry 20110520

• Mouse FKBP23 mediates conformer-specific functions of BiP by catalyzing Pro117 cis/trans isomerization.

  Biochemical and biophysical research communications 20110520

• A QM/QM investigation of the hUNG2 reaction surface: the untold tale of a catalytic residue.

  Biochemistry 20110517

• Hexaconazole induces antioxidant protection and apigenin-7-glucoside accumulation in Matricaria chamomilla plants subjected to drought stress.

  Journal of plant physiology 20110515

• Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor.

  Bioorganic & medicinal chemistry letters 20110515

• DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein.

  The Journal of biological chemistry 20110513

• Microscopic analysis of protein oxidative damage: effect of carbonylation on structure, dynamics, and aggregability of villin headpiece.

  Journal of the American Chemical Society 20110511

• Insight into potential toxicity mechanisms of melamine: an in silico study.

  Toxicology 20110510

• Microwave-assisted solid-phase aza-peptide synthesis: aza scan of a PKB/Akt inhibitor using aza-arginine and aza-proline precursors.

  The Journal of organic chemistry 20110506

• NMR investigations on the proline-catalyzed aldehyde self-condensation: Mannich mechanism, dienamine detection, and erosion of the aldol addition selectivity.

  The Journal of organic chemistry 20110506

• Enzymatic preparation of 5-hydroxy-L-proline, N-Cbz-5-hydroxy-L-proline, and N-Boc-5-hydroxy-L-proline from (α-N-protected)-L-ornithine using a transaminase or an amine oxidase.

  Enzyme and microbial technology 20110506

• The combination of prolinoamino acids and cyclopropylamino acids leads to fully functionalized, stable β-turns in water.

  Chembiochem : a European journal of chemical biology 20110502

• Estimation of inhibitory quotient using a comparative equilibrium dialysis assay for prediction of viral response to hepatitis C virus inhibitors.

  Journal of viral hepatitis 20110501

• Proline induces calcium-mediated oxidative burst and salicylic acid signaling.

  Amino acids 20110501

• Comparative antioxidative responses and proline metabolism in two wheat cultivars under short term lead stress.

  Ecotoxicology and environmental safety 20110501

• Drosophila delta-1-pyrroline-5-carboxylate dehydrogenase (P5CDh) is required for proline breakdown and mitochondrial integrity-Establishing a fly model for human type II hyperprolinemia.

  Mitochondrion 20110501

• Preventing arginine-to-proline conversion in a cell-line-independent manner during cell cultivation under stable isotope labeling by amino acids in cell culture (SILAC) conditions.

  Analytical biochemistry 20110501

• L-Proline nutrition and catabolism in Staphylococcus saprophyticus.

  Antonie van Leeuwenhoek 20110501

• Influence of Ser/Pro-rich domain and kinase domain of double cortin-like protein kinase on microtubule-binding activity.

  Journal of biochemistry 20110501

• Detection of chiral defects in crystalline organic solids using solid-state NMR spectroscopy.

  Journal of pharmaceutical sciences 20110501

• TGF-β1 gene polymorphism in renal transplant patients with and without gingival overgrowth.

  Oral diseases 20110501

• A role for proline synthesis and transport in Listeria monocytogenes barotolerance.

  Journal of applied microbiology 20110501

• C- and N-catabolic utilization of tricarboxylic acid cycle-related amino acids by Scheffersomyces stipitis and other yeasts.

  Yeast (Chichester, England) 20110501

• Desiccation of the resurrection plant Haberlea rhodopensis at high temperature.

  Photosynthesis research 20110501

• Reduced secretagogin expression in the hippocampus of P301L tau transgenic mice.

  Journal of neural transmission (Vienna, Austria : 1996) 20110501

• Neuronal ceroid lipofuscinosis in Qatar: report of a novel mutation in ceroid-lipofuscinosis, neuronal 5 in the Arab population.

  Journal of child neurology 20110501

• A new standard of care for the treatment of chronic HCV infection.

  Nature reviews. Gastroenterology & hepatology 20110501

• Effect of the identity of Xaa on the fragmentation modes of doubly-protonated Ala-Ala-Xaa-Ala-Ala-Ala-Arg.

  Journal of the American Society for Mass Spectrometry 20110501

• Water stress induces up-regulation of DOF1 and MIF1 transcription factors and down-regulation of proteins involved in secondary metabolism in amaranth roots (Amaranthus hypochondriacus L.).

  Plant biology (Stuttgart, Germany) 20110501

• Tyrosine nitration within the proline-rich region of Tau in Alzheimer's disease.

  The American journal of pathology 20110501

• Effects of the group II mGlu receptor agonist 2R,4R-APDC on dentate gyrus cell proliferation in the adult rat brain after diffuse brain injury.

  Neurological research 20110501

• Viral hepatitis: progress and promise.

  Nature reviews. Gastroenterology & hepatology 20110501

• [The impact of PDTC on circulating tumor cells of laryngocarcinoma in nude mice model].

  Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20110501

• D-Ornithine coopts pyrrolysine biosynthesis to make and insert pyrroline-carboxy-lysine.

  Nature chemical biology 20110427

• Structural features and ligand binding properties of tandem WW domains from YAP and TAZ, nuclear effectors of the Hippo pathway.

  Biochemistry 20110426

• Proline-catalysed amination reactions in cyclic carbonate solvents.

  Molecules (Basel, Switzerland) 20110421

• Quantum-cascade laser-based vibrational circular dichroism.

  Journal of the American Chemical Society 20110420

• TaSRG, a wheat transcription factor, significantly affects salt tolerance in transgenic rice and Arabidopsis.

  FEBS letters 20110420

• Tunable, post-translational hydroxylation of collagen Domains in Escherichia coli.

  ACS chemical biology 20110415

• Mutations in PPIB (cyclophilin B) delay type I procollagen chain association and result in perinatal lethal to moderate osteogenesis imperfecta phenotypes.

  Human molecular genetics 20110415

• Functional and topological analysis of Pen-2, the fourth subunit of the gamma-secretase complex.

  The Journal of biological chemistry 20110408

• Determination of sodium benzoate by chiral ligand exchange CE based on its inhibitory activity in D-amino acid oxidase mediated oxidation of D-serine.

  Analytica chimica acta 20110408

• Infectious diseases. First specific drugs raise hopes for hepatitis C.

  Science (New York, N.Y.) 20110408

• Proline and hydroxyproline metabolism: implications for animal and human nutrition.

  Amino acids 20110401

• Proline-specific extracellular aminopeptidase purified from Streptomyces lavendulae.

  Applied biochemistry and biotechnology 20110401

• Manganese superoxide dismutase dimorphism relationship with severity and prognosis in cardiogenic shock due to dilated cardiomyopathy.

  Free radical research 20110401

• Altered self-assembly and apatite binding of amelogenin induced by N-terminal proline mutation.

  Archives of oral biology 20110401

• Molecular analysis of the PGYRP (proline-, glycine- and tyrosine-rich protein) gene family in soybean.

  Molecular biology reports 20110401

• Mutational and transcriptional analyses of the Staphylococcus aureus low-affinity proline transporter OpuD during in vitro growth and infection of murine tissues.

  FEMS immunology and medical microbiology 20110401

• T-box-mediated control of the anabolic proline biosynthetic genes of Bacillus subtilis.

  Microbiology (Reading, England) 20110401

• Cleft lip with cleft palate, ankyloglossia, and hypodontia are associated with TBX22 mutations.

  Journal of dental research 20110401

• Pharmacology of a new tritiated endomorphin-2 analog containing the proline mimetic cis-2-aminocyclohexanecarboxylic acid.

  Peptides 20110401

• The ALS8-associated mutant VAPB(P56S) is resistant to proteolysis in neurons.

  Journal of neurochemistry 20110401

• Development of chemically defined media supporting high cell density growth of Ketogulonicigenium vulgare and Bacillus megaterium.

  Bioresource technology 20110401

• Control of embryonic stem cell metastability by L-proline catabolism.

  Journal of molecular cell biology 20110401

• Proline dehydrogenase contributes to pathogen defense in Arabidopsis.

  Plant physiology 20110401

• Influence of proline-rich inositol polyphosphate 5-phosphatase, on early development of fertilized mouse eggs, via inhibition of phosphorylation of Akt.

  Cell proliferation 20110401

• Developmental cardiac hypertrophy in a mouse model of prolidase deficiency.

  Birth defects research. Part A, Clinical and molecular teratology 20110401

• Isolation and characterization of proline/betaine transporter gene from oil palm.

  Tree physiology 20110401

• Boceprevir for untreated chronic HCV genotype 1 infection.

  The New England journal of medicine 20110331

• Boceprevir for previously treated chronic HCV genotype 1 infection.

  The New England journal of medicine 20110331

• A new era of hepatitis C therapy begins.

  The New England journal of medicine 20110331

• Natural osmolytes remodel the aggregation pathway of mutant huntingtin exon 1.

  Biochemistry 20110329

• One-pot Eschenmoser episulfide contractions in DMSO: applications to the synthesis of fuligocandins A and B and a number of vinylogous amides.

  The Journal of organic chemistry 20110318

• Lower limb areflexia without central and peripheral conduction abnormalities is highly suggestive of Gerstmann-Sträussler-Scheinker disease Pro102Leu.

  Journal of the neurological sciences 20110315

• Continuous flow thermolysis of azidoacrylates for the synthesis of heterocycles and pharmaceutical intermediates.

  Chemical communications (Cambridge, England) 20110307

• Asymmetric aldol reaction organocatalyzed by (S)-proline-containing dipeptides: improved stereoinduction under solvent-free conditions.

  The Journal of organic chemistry 20110304

• Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability.

  Neurobiology of aging 20110301

• Amelioration of salinity stress by exogenously applied spermidine or spermine in three varieties of indica rice differing in their level of salt tolerance.

  Journal of plant physiology 20110301

• An amelogenin mutation leads to disruption of the odontogenic apparatus and aberrant expression of Notch1.

  Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20110301

• Compatible solute biosynthesis in cyanobacteria.

  Environmental microbiology 20110301

• Characterization of human liver enzymes involved in the biotransformation of boceprevir, a hepatitis C virus protease inhibitor.

  Drug metabolism and disposition: the biological fate of chemicals 20110301

• Nitric oxide in enteric nervous system mediated the inhibitory effect of vasopressin on the contraction of circular muscle strips from colon in male rats.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110301

• Novel mutation in MYH7 gene associated with distal myopathy and cardiomyopathy.

  Neuromuscular disorders : NMD 20110301

• The results of Phase III clinical trials with telaprevir and boceprevir presented at the Liver Meeting 2010: a new standard of care for hepatitis C virus genotype 1 infection, but with issues still pending.

  Gastroenterology 20110301

• Anti-arthritic active fraction of Capparis spinosa L. fruits and its chemical constituents.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110301

• Additional phenotypic features of Muenke syndrome in 2 Dutch families.

  The Journal of craniofacial surgery 20110301

• Craniofacial growth in patients with FGFR3Pro250Arg mutation after fronto-orbital advancement in infancy.

  The Journal of craniofacial surgery 20110301

• Effects of polynitrogen compounds on the activity of recombinant human HIF-1α prolyl hydroxylase 3 in E. coli.

  Journal of inorganic biochemistry 20110301

• Overexpression of AtNHX5 improves tolerance to both salt and drought stress in Broussonetia papyrifera (L.) Vent.

  Tree physiology 20110301

• An investigation into the origin of the dramatically reduced reactivity of peptide-prolyl-thioesters in native chemical ligation.

  Chemical communications (Cambridge, England) 20110227

• Effect of exogenous γ-aminobutyric acid treatment on proline accumulation and chilling injury in peach fruit after long-term cold storage.

  Journal of agricultural and food chemistry 20110223

• Proline 96 of the copper ligand loop of amicyanin regulates electron transfer from methylamine dehydrogenase by positioning other residues at the protein-protein interface.

  Biochemistry 20110222

• cis-Proline-mediated Ser(P)5 dephosphorylation by the RNA polymerase II C-terminal domain phosphatase Ssu72.

  The Journal of biological chemistry 20110218

• Electrochemical investigation of cellular uptake of quantum dots decorated with a proline-rich cell penetrating peptide.

  Bioconjugate chemistry 20110216

• A statistical analysis of the PPII propensity of amino acid guests in proline-rich peptides.

  Biophysical journal 20110216

• Basal and antigen-induced exposure of the proline-rich sequence in CD3ε.

  Journal of immunology (Baltimore, Md. : 1950) 20110215

• Drugs in development for viral hepatitis: care and caution.

  Drugs 20110212

• (Pro2 H+)2 (TCNQ.-)2⋅TCNQ: an amino acid derived semiconductor.

  Angewandte Chemie (International ed. in English) 20110211

• Effect of administration of oral contraceptives on the synthesis and breakdown of myofibrillar proteins in young women.

  Scandinavian journal of medicine & science in sports 20110201

• Significant association of high-risk human papillomavirus (HPV) but not of p53 polymorphisms with oral squamous cell carcinomas in Malaysia.

  Journal of cancer research and clinical oncology 20110201

• Exogenous proline effects on water relations and ions contents in leaves and roots of young olive.

  Amino acids 20110201

• Glucose deficiency reduces collagen synthesis in breast cancer MCF7 cells.

  Cell biology international 20110201

• Characterization of a novel dye-linked L-proline dehydrogenase from an aerobic hyperthermophilic archaeon, Pyrobaculum calidifontis.

  Applied microbiology and biotechnology 20110201

• Differential effects of nitric oxide on blood-brain barrier integrity and cerebral blood flow in intracerebral C6 gliomas.

  Neuro-oncology 20110201

• Big changes are coming in hepatitis C.

  Current gastroenterology reports 20110201

• Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown.

  American journal of physiology. Lung cellular and molecular physiology 20110201

• Introduction of glycine and proline residues onto protein surface increases the thermostability of endoglucanase CelA from Clostridium thermocellum.

  Bioresource technology 20110201

• Enhancement of laccase activity through the construction and breakdown of a hydrogen bond at the type I copper center in Escherichia coli CueO and the deletion mutant Δα5-7 CueO.

  Biochemistry 20110201

• Dcp1 links coactivators of mRNA decapping to Dcp2 by proline recognition.

  RNA (New York, N.Y.) 20110201

• Nitric oxide-releasing electrospun polymer microfibers.

  ACS applied materials & interfaces 20110201

• Hepatitis in 2010: the dawn of a new era in HCV therapy.

  Nature reviews. Gastroenterology & hepatology 20110201

• Amino acid-induced gene expression profiling in clonal β-cell line INS-1E cells.

  Diabetes/metabolism research and reviews 20110201

• Purification, crystallization and preliminary crystallographic analysis of the SH2 domain of IL-2-inducible T-cell kinase.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20110201

• Novel X-linked inhibitor of apoptosis protein inhibitors as probes of apoptosis in biology and medicine.

  Experimental biology and medicine (Maywood, N.J.) 20110201

• L-proline-stabilized human IgG: Privigen® 10% for intravenous use and Hizentra® 20% for subcutaneous use.

  Immunotherapy 20110201

• Lead phytotoxicity on wheat (Triticum aestivum L.) seed germination and seedlings growth.

  Comptes rendus biologies 20110201

• Naturally occurring biodegradable polymers as the basis of chiral gels for the distinction of enantiomers by partially oriented NMR spectroscopy.

  The International journal of artificial organs 20110201

• Identification of H-Ras-specific motif for the activation of invasive signaling program in human breast epithelial cells.

  Neoplasia (New York, N.Y.) 20110201

• The relationship of proline content and metabolism on the productivity of maize plants.

  Plant signaling & behavior 20110201

• Detection and diversity of a putative novel heterogeneous polymorphic proline-glycine repeat (Pgr) protein in the footrot pathogen Dichelobacter nodosus.

  Veterinary microbiology 20110127

• A practical synthesis of trans-3-substituted proline derivatives through 1,4-addition.

  Organic letters 20110121

• Prolyl hydroxylation- and glycosylation-dependent functions of Skp1 in O2-regulated development of Dictyostelium.

  Developmental biology 20110115

• Gender differences in the effects of peroxisome proliferator-activated receptor γ2 gene polymorphisms on metabolic adversity in patients with schizophrenia or schizoaffective disorder.

  Progress in neuro-psychopharmacology & biological psychiatry 20110115

• Human VAPA and the yeast VAP Scs2p with an altered proline distribution can phenocopy amyotrophic lateral sclerosis-associated VAPB(P56S).

  Biochemical and biophysical research communications 20110114

• Proline derivatives in fruits of bergamot (Citrus bergamia Risso et Poit): presence of N-methyl-L-proline and 4-hydroxy-L-prolinebetaine.

  Journal of agricultural and food chemistry 20110112

• ERK1/2 phosphorylate Raptor to promote Ras-dependent activation of mTOR complex 1 (mTORC1).

  The Journal of biological chemistry 20110107

• Alterations in plasma amino acid levels in chronic pancreatitis.

  JOP : Journal of the pancreas 20110105

• Forced expression of Mdmyb10, a myb transcription factor gene from apple, enhances tolerance to osmotic stress in transgenic Arabidopsis.

  Molecular biology reports 20110101

• Protective response of 28-homobrassinolide in cultivars of Triticum aestivum with different levels of nickel.

  Archives of environmental contamination and toxicology 20110101

• Nuclear factor kappa B pathway down-regulates aquaporin 5 in the nasal mucosa of rats with allergic rhinitis.

  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20110101

• Triple Hyp→Pro replacement in integramide A, a peptaib inhibitor of HIV-1 integrase: Effect on conformation and bioactivity.

  Biopolymers 20110101

• Thermodynamic and kinetic consequences of substituting glycine at different positions in a Pro-Hyp-Gly repeat collagen model peptide.

  Biopolymers 20110101

• Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2).

  Biochimica et biophysica acta 20110101

• Conformational preference and cis-trans isomerization of 4-methylproline residues.

  Biopolymers 20110101

• Proline-rich cytokine from neurosecretory granules: a new natural substrate for dipeptidyl peptidase IV.

  Neurochemical research 20110101

• Arginine is synthesized from proline, not glutamate, in enterally fed human preterm neonates.

  Pediatric research 20110101

• Analogs of the CLV3 peptide: synthesis and structure-activity relationships focused on proline residues.

  Plant & cell physiology 20110101

• In planta function of compatible solute transporters of the AtProT family.

  Journal of experimental botany 20110101

• OVP1, a vacuolar H+-translocating inorganic pyrophosphatase (V-PPase), overexpression improved rice cold tolerance.

  Plant physiology and biochemistry : PPB 20110101

• Enteral arginase II provides ornithine for citrulline synthesis.

  American journal of physiology. Endocrinology and metabolism 20110101

• Inhibition of nuclear factor κB regresses cardiac hypertrophy by modulating the expression of extracellular matrix and adhesion molecules.

  Free radical biology & medicine 20110101

• Expression analysis of proline rich 15 (Prr15) in mouse and human gastrointestinal tumors.

  Molecular carcinogenesis 20110101

• Extracellular matrix production by adipose-derived stem cells: implications for heart valve tissue engineering.

  Biomaterials 20110101

• Enhancing the thermal stability of a single-chain Fv fragment by in vivo global fluorination of the proline residues.

  Molecular bioSystems 20110101

• Structural basis for regulation of the Crk signaling protein by a proline switch.

  Nature chemical biology 20110101

• The influence of passive stretch and NF-κB inhibitors on the morphology of dystrophic muscle fibers.

  Anatomical record (Hoboken, N.J. : 2007) 20110101

• [Future of antiviral therapy for chronic hepatitis C. Direct antiviral acting medications].

  Pharmazie in unserer Zeit 20110101

• The role of triple therapy with protease inhibitors in hepatitis C virus genotype 1 naïve patients.

  Liver international : official journal of the International Association for the Study of the Liver 20110101

• The role of triple therapy in HCV genotype 1-experienced patients.

  Liver international : official journal of the International Association for the Study of the Liver 20110101

• New direct-acting antivirals' combination for the treatment of chronic hepatitis C.

  Liver international : official journal of the International Association for the Study of the Liver 20110101

• A self-propagating matrix metalloprotease-9 (MMP-9) dependent cycle of chronic neutrophilic inflammation.

  PloS one 20110101

• Local tolerance and stability up to 24 months of a new 20% proline-stabilized polyclonal immunoglobulin for subcutaneous administration.

  Biologicals : journal of the International Association of Biological Standardization 20110101

• Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

• Use of cis-[18F]fluoro-proline for assessment of exercise-related collagen synthesis in musculoskeletal connective tissue.

  PloS one 20110101

• [L-proline assay in biological material by capillary zone electrophoresis].

  Klinicheskaia laboratornaia diagnostika 20110101

• Relationship between depression anxiety stress scale (DASS) and urinary hydroxyproline and proline concentrations in hospital workers.

  Journal of preventive medicine and public health = Yebang Uihakhoe chi 20110101

• Chirality responsive helical poly(phenylacetylene) bearing L-proline pendants.

  Chirality 20110101

• A novel mutation in γD-crystallin associated with autosomal dominant congenital cataract in a Chinese family.

  Molecular vision 20110101

• PPAR-gamma2 pro12Ala polymorphism is associated with post-challenge abnormalities of glucose homeostasis in children and adolescents with obesity.

  Journal of pediatric endocrinology & metabolism : JPEM 20110101

• The expression of a xylanase targeted to ER-protein bodies provides a simple strategy to produce active insoluble enzyme polymers in tobacco plants.

  PloS one 20110101

• Determination of proline enantiomers in honey and royal jelly by LC-UV.

  Journal of AOAC International 20110101

• Extraction of consensus protein patterns in regions containing non-proline cis peptide bonds and their functional assessment.

  BMC bioinformatics 20110101

• Rational design of protein stability: effect of (2S,4R)-4-fluoroproline on the stability and folding pathway of ubiquitin.

  PloS one 20110101

• Testis-specific glyceraldehyde-3-phosphate dehydrogenase: origin and evolution.

  BMC evolutionary biology 20110101

• Functionalizable oligoprolines as molecular scaffolds.

  Chimia 20110101

• LyGDI, a novel SHIP-interacting protein, is a negative regulator of FcγR-mediated phagocytosis.

  PloS one 20110101

• Amino-terminal extension present in the methionine aminopeptidase type 1c of Mycobacterium tuberculosis is indispensible for its activity.

  BMC biochemistry 20110101

• Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-κB/COX-2 pathway.

  PloS one 20110101

• [Association of gene TP53 polymorphic marker Pro72Arg with clinical characteristics of chronic glomerulonephritis].

  Terapevticheskii arkhiv 20110101

• Nuclear factor-κB inhibitors alleviate nivalenol-induced cytotoxicity in HL60 cells.

  Environmental toxicology and pharmacology 20110101

• An upstream estrogen response element linked to exogenous p53 tumor suppressor gene expression differentiates effects of the codon 72 polymorphism.

  Asian Pacific journal of cancer prevention : APJCP 20110101

• Impact of ribavirin on HCV replicon RNA decline during treatment with interferon-α and the protease inhibitors boceprevir or telaprevir.

  Antiviral therapy 20110101

• Global analysis of proline-rich tandem repeat proteins reveals broad phylogenetic diversity in plant secretomes.

  PloS one 20110101

• Pharmacological enhancement of glutamate transport reduces excitotoxicity in vitro.

  Restorative neurology and neuroscience 20110101

• Reduction of neutrophil activity decreases early microvascular injury after subarachnoid haemorrhage.

  Journal of neuroinflammation 20110101

• [Strategy for the development of dipeptide drugs].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20110101

• New therapies for hepatitis C virus infection.

  Missouri medicine 20110101

• [Study of gly-proline-containing peptides (PGP and GPGPGP) degradation by aggressive factors in vitro].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20110101

• Characterization of polysaccharide from Astragalus radix as the macrophage stimulator.

  Cellular immunology 20110101

• NO-dependent accumulation of inorganic ions and proline determines the protective effect of nitric oxide on mustard growth under the conditions of salinization.

  Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20110101

• Proline and COMT status affect visual connectivity in children with 22q11.2 deletion syndrome.

  PloS one 20110101

• TNFα-induced necroptosis and autophagy via supression of the p38-NF-κB survival pathway in L929 cells.

  Journal of pharmacological sciences 20110101

• Evidence for a sodium-dependent proline and glycine-betaine uptake in the cyanobacterium Nostoc muscorum.

  Mikrobiologiia 20110101

• Anatomical and physiological plasticity in Leymus chinensis (Poaceae) along large-scale longitudinal gradient in northeast China.

  PloS one 20110101

• The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement.

  PloS one 20110101

• Characterization of the basic charge variants of a human IgG1: effect of copper concentration in cell culture media.

  mAbs 20110101

• Impact of HCV protease-inhibitor-based triple therapy for chronic HCV genotype 1 infection.

  Antiviral therapy 20110101

• Hepatitis C therapy in 2011: is less more, is more less?

  The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20110101

• Seasonal changes in the mannitol and proline contents of the brown alga Fucus vesiculosus L. on the Murman coast of the Barents Sea.

  Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20110101

• [The effect of semax and its C-end peptide PGP on expression of the neurotrophins and their receptors in the rat brain during incomplete global ischemia].

  Molekuliarnaia biologiia 20110101

• [The unusual thermodynamic properties of compact forms pFh fragments (hinge region) IgG3 Kuc and Sur].

  Molekuliarnaia biologiia 20110101

• IL28B polymorphism -- predictive factor of HCV infected genotype 1 individuals to treatment response and management of therapy.

  Romanian journal of internal medicine = Revue roumaine de medecine interne 20110101

• PPARγ2 gene Pro12Ala and PPARα gene Leu162Val single nucleotide polymorphisms interact with dietary intake of fat in determination of plasma lipid concentrations.

  Journal of nutrigenetics and nutrigenomics 20110101

• Mechanistic studies of peptide self-assembly: transient α-helices to stable β-sheets.

  Journal of the American Chemical Society 20101229

• Mechanism of the organocatalyzed decarboxylative Knoevenagel-Doebner reaction. A theoretical study.

  The journal of physical chemistry. A 20101223

• Steric factors override thermodynamic driving force in regioselectivity of proline hydroxylation by prolyl-4-hydroxylase enzymes.

  The journal of physical chemistry. A 20101223

• The proline/arginine-rich domain is a major determinant of dynamin self-activation.

  Biochemistry 20101221

• Proline periodicity modulates the self-assembly properties of elastin-like polypeptides.

  The Journal of biological chemistry 20101217

• Molecular mechanisms modulating glutamate kinase activity. Identification of the proline feedback inhibitor binding site.

  Journal of molecular biology 20101217

• Prolidase-dependent regulation of TGF β (corrected) and TGF β receptor expressions in human skin fibroblasts.

  European journal of pharmacology 20101215

• Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 in patients with fatty liver diseases.

  World journal of gastroenterology 20101214

• Structural basis for the properties of two single-site proline mutants of CYP102A1 (P450BM3).

  Chembiochem : a European journal of chemical biology 20101210

• Interfacial and emulsifying properties of designed β-strand peptides.

  Langmuir : the ACS journal of surfaces and colloids 20101207

• A diastereoselective three-component coupling approach to highly substituted pyrrolidines.

  The Journal of organic chemistry 20101203

• Water-induced switching of β-structure to polyproline II conformation in the 4S-aminoproline polypeptide via H-bond rearrangement.

  Organic letters 20101203

• Microscopic mechanism of specific peptide adhesion to semiconductor substrates.

  Angewandte Chemie (International ed. in English) 20101203

• Kinetic evidence for the formation of oxazolidinones in the stereogenic step of proline-catalyzed reactions.

  Angewandte Chemie (International ed. in English) 20101203

• Expressions of lymphotactin and its receptor, XCR, in Lewis rats with experimental autoimmune anterior uveitis.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20101201

• p53 Pro72Arg polymorphism and prostate cancer in men of African descent.

  The Prostate 20101201

• Development and validation of a GC method for quantitative determination of enantiomeric purity of a proline derivative.

  Journal of pharmaceutical and biomedical analysis 20101201

• α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6ß4 and α6ß2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101201

• Deficiency in plastidic glutamine synthetase alters proline metabolism and transcriptomic response in Lotus japonicus under drought stress.

  The New phytologist 20101201

• Recombinant human sperm-specific glyceraldehyde-3-phosphate dehydrogenase: structural basis for enhanced stability.

  Biochimica et biophysica acta 20101201

• Susceptibility of treatment-naive hepatitis C virus (HCV) clinical isolates to HCV protease inhibitors.

  Antimicrobial agents and chemotherapy 20101201

• Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20101201

• Methodological remarks concerning the recent meta-analysis on p53 codon 72 polymorphism and colorectal cancer risk.

  European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20101201

• Role of TP53 Arg72Pro polymorphism in urinary bladder cancer predisposition and predictive impact of proline related genotype in advanced tumors in an ethnic Kashmiri population.

  Cancer genetics and cytogenetics 20101201

• Applications and modifications of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) in peptides and peptidomimetics design and discovery.

  Current protein & peptide science 20101201

• [Effect of dipeptide neurotensin analog dilept on extracellular concentrations of glutamate, GABA and HVA in N. accumbens of rat brain].

  Eksperimental'naia i klinicheskaia farmakologiia 20101201

• Copper(II) complex formation with a linear peptide encompassing the putative cell binding site of angiogenin.

  Dalton transactions (Cambridge, England : 2003) 20101128

• Intramolecular hydroamination of dithioketene acetals: an easy route to cyclic amino acid derivatives.

  Organic letters 20101119

• Understanding cold denaturation: the case study of Yfh1.

  Journal of the American Chemical Society 20101117

• On the roles of substrate binding and hinge unfolding in conformational changes of adenylate kinase.

  Biophysical journal 20101117

• Rapid desensitization of the rat α7 nAChR is facilitated by the presence of a proline residue in the outer β-sheet.

  The Journal of physiology 20101115

• Structural basis of cyclophilin B binding by the calnexin/calreticulin P-domain.

  The Journal of biological chemistry 20101112

• Conformational preferences of X-Pro sequences: Ala-Pro and Aib-Pro motifs.

  The journal of physical chemistry. B 20101111

• Replacing 32 proline residues by a noncanonical amino acid results in a highly active DNA polymerase.

  Journal of the American Chemical Society 20101110

• High-yielding synthesis of the anti-influenza neuraminidase inhibitor (-)-oseltamivir by two 'one-pot' sequences.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20101108

• Is β-homo-proline a pseudo-γ-turn forming element of β-peptides? An IR and VCD spectroscopic study on Ac-β-HPro-NHMe in cryogenic matrices and solutions.

  Physical chemistry chemical physics : PCCP 20101107

• Propensities of aromatic amino acids versus leucine and proline to induce residual structure in the denatured-state ensemble of iso-1-cytochrome c.

  Journal of molecular biology 20101105

• Highly stereoselective and scalable anti-aldol reactions using N-(p-dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide: scope and origins of stereoselectivities.

  The Journal of organic chemistry 20101105

• Synthesis of a dimer of β-(1,4)-L-arabinosyl-(2S,4R)-4-hydroxyproline inspired by Art v 1, the major allergen of mugwort.

  Organic letters 20101105

• The conformation and the aggregation kinetics of α-synuclein depend on the proline residues in its C-terminal region.

  Biochemistry 20101102

• Responses of wheat roots to exogenous selenium supply under enhanced ultraviolet-B.

  Biological trace element research 20101101

• Amino acids stimulate Akt phosphorylation, and reduce IL-8 production and NF-κB activity in HepG2 liver cells.

  Molecular nutrition & food research 20101101

• Mechanisms independent of abscisic acid (ABA) or proline feedback have a predominant role in transcriptional regulation of proline metabolism during low water potential and stress recovery.

  Plant, cell & environment 20101101

• Desiccation-induced physiological and biochemical changes in resurrection plant, Selaginella bryopteris.

  Journal of plant physiology 20101101

• Comparison of hormonal responses to heat, drought and combined stress in tobacco plants with elevated proline content.

  Journal of plant physiology 20101101

• Molecular dynamics simulations of Aβ fibril interactions with β-sheet breaker peptides.

  Peptides 20101101

• Compatible solutes: Thermodynamic properties and biological impact of ectoines and prolines.

  Biophysical chemistry 20101101

• Preclinical characterization of BI 201335, a C-terminal carboxylic acid inhibitor of the hepatitis C virus NS3-NS4A protease.

  Antimicrobial agents and chemotherapy 20101101

• Efficient protein production method for NMR using soluble protein tags with cold shock expression vector.

  Journal of biomolecular NMR 20101101

• Effects of long-term cadmium exposure on growth and metabolomic profile of tomato plants.

  Ecotoxicology and environmental safety 20101101

• Over-expression of PR-10a leads to increased salt and osmotic tolerance in potato cell cultures.

  Journal of biotechnology 20101101

• Taste genes associated with dental caries.

  Journal of dental research 20101101

• A helix-breaking mutation in the epithelial Ca(2+) channel TRPV5 leads to reduced Ca(2+)-dependent inactivation.

  Cell calcium 20101101

• Correlation between genotype and supernumerary tooth formation in cleidocranial dysplasia.

  Orthodontics & craniofacial research 20101101

• Effect of glyprolines PGP, GP, and PG on homeostasis of gastric mucosa in rats with experimental ethanol-induced gastric ulcers.

  Bulletin of experimental biology and medicine 20101101

• Pro198Leu polymorphism of GPx-1 gene and activity of erythrocytic glutathione peroxidase and lipid peroxidation products.

  Bulletin of experimental biology and medicine 20101101

• [Association of PPARgamma2 Pro12Ala polymorphism and cognitive dysfunction in hypertension patients].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20101101

• Effect of calcium against salinity-induced inhibition in growth, ion accumulation and proline contents in Cichorium intybus L.

  Journal of environmental biology 20101101

• Identification of metastable states in peptide's dynamics.

  The Journal of chemical physics 20101028

• Entropy drives an attached water molecule from the C- to N-terminus on protonated proline.

  Journal of the American Chemical Society 20101027

• Conformational profile of a proline-arginine hybrid.

  Journal of chemical information and modeling 20101025

• The role of proline in the membrane re-entrant helix of caveolin-1.

  The Journal of biological chemistry 20101022

• Transmembrane helix I and periplasmic loop 1 of Escherichia coli ProP are involved in osmosensing and osmoprotectant transport.

  Biochemistry 20101019

• Potent inhibition of HIV-1 entry with a chemically programmed antibody aided by an efficient organocatalytic synthesis.

  Chembiochem : a European journal of chemical biology 20101018

• Hydrogels of collagen-inspired telechelic triblock copolymers for the sustained release of proteins.

  Journal of controlled release : official journal of the Controlled Release Society 20101015

• Ablation of succinate production from glucose metabolism in the procyclic trypanosomes induces metabolic switches to the glycerol 3-phosphate/dihydroxyacetone phosphate shuttle and to proline metabolism.

  The Journal of biological chemistry 20101015

• Silicon effects on photosynthesis and antioxidant parameters of soybean seedlings under drought and ultraviolet-B radiation.

  Journal of plant physiology 20101015

• Asymmetric synthesis of (R)-antofine and (R)-cryptopleurine via proline-catalyzed sequential α-aminoxylation and Horner-Wadsworth-Emmons olefination of aldehyde.

  The Journal of organic chemistry 20101015

• Characterization of warfarin unusual peak profiles on oligoproline chiral high performance liquid chromatography columns.

  Journal of chromatography. A 20101015

• Functional analyses of ethylene response factor JERF3 with the aim of improving tolerance to drought and osmotic stress in transgenic rice.

  Transgenic research 20101001

• Biological effect markers in exhaled breath condensate and biomonitoring in welders: impact of smoking and protection equipment.

  International archives of occupational and environmental health 20101001

• Shock wave induces chronic renal lesion through activation of the nuclear factor kappa B signaling pathway.

  World journal of urology 20101001

• Proline metabolism and transport in plant development.

  Amino acids 20101001

• 5-aminoimidazole-4-carboxamide ribonucleoside and AMP-activated protein kinase inhibit signalling through NF-κB.

  Immunology and cell biology 20101001

• Association of P53 codon 72 polymorphism and ameloblastoma.

  Oral diseases 20101001

• Toxicological evaluation of L-proline in a 90-day feeding study with Fischer 344 rats.

  Regulatory toxicology and pharmacology : RTP 20101001

• Sex-related adaptive responses to interaction of drought and salinity in Populus yunnanensis.

  Plant, cell & environment 20101001

• Bentazon triggers the promotion of oxidative damage in the Portuguese ricefield cyanobacterium Anabaena cylindrica: response of the antioxidant system.

  Environmental toxicology 20101001

• Structural flexibility and the positive charges are the key factors in bacterial cell selectivity and membrane penetration of peptoid-substituted analog of Piscidin 1.

  Biochimica et biophysica acta 20101001

• Up-regulating arginase contributes to amelioration of chilling stress and the antioxidant system in cherry tomato fruits.

  Journal of the science of food and agriculture 20101001

• Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism.

  Human molecular genetics 20101001

• Synthesis and activity of endomorphin-2 and morphiceptin analogues with proline surrogates in position 2.

  European journal of medicinal chemistry 20101001

• Acetoacetanilides as masked isocyanates: facile and efficient synthesis of unsymmetrically substituted ureas.

  Organic letters 20101001

• A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation.

  Science (New York, N.Y.) 20101001

• Messy biology and the origins of evolutionary innovations.

  Nature chemical biology 20101001

• Expression analysis of proline metabolism-related genes from halophyte Arabis stelleri under osmotic stress conditions.

  Journal of integrative plant biology 20101001

• Medicine. Neutrophils find smoke attractive.

  Science (New York, N.Y.) 20101001

• Platelet gel in the treatment of cutaneous ulcers: the experience of the Immunohaematology and Transfusion Centre of Parma.

  Blood transfusion = Trasfusione del sangue 20101001

• New cancer targets emerging from studies of the Von Hippel-Lindau tumor suppressor protein.

  Annals of the New York Academy of Sciences 20101001

• Experimental verification of force fields for molecular dynamics simulations using Gly-Pro-Gly-Gly.

  The journal of physical chemistry. B 20100930

• Pharmacology of a potent and selective inhibitor of PDE4 for inhaled administration.

  European journal of pharmacology 20100925

• Theoretical study on the structure and cation-anion interaction of amino acid cation based amino acid ionic liquid [Pro]+[NO3]−.

  The journal of physical chemistry. A 20100923

• Enantioselective rearrangement of proline sulfonamides: an easy entry to enantiomerically pure α-aryl quaternary prolines.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100917

• Adsorption equilibria of proline in hydrophilic interaction chromatography.

  Journal of chromatography. A 20100917

• Crystal structure of TTHA0061, an uncharacterized protein from Thermus thermophilus HB8, reveals a novel fold.

  Biochemical and biophysical research communications 20100917

• Conformational preferences of proline analogues with a fused benzene ring.

  The journal of physical chemistry. B 20100916

• C-reactive protein triggers inflammatory responses partly via TLR4/IRF3/NF-κB signaling pathway in rat vascular smooth muscle cells.

  Life sciences 20100911

• Intramolecular hydrogen bond-controlled prolyl amide isomerization in glucosyl 3(S)-hydroxy-5-hydroxymethylproline hybrids: a computational study.

  The journal of physical chemistry. B 20100909

• Development of a 2-aza-Cope-[3 + 2] dipolar cycloaddition strategy for the synthesis of quaternary proline scaffolds.

  Organic letters 20100903

• A bacterial mRNA leader that employs different mechanisms to sense disparate intracellular signals.

  Cell 20100903

• Redox homeostasis, antioxidant defense, and methylglyoxal detoxification as markers for salt tolerance in Pokkali rice.

  Protoplasma 20100901

• Structural determinants stabilizing helical distortions related to proline.

  Journal of structural biology 20100901

• The proline 160 in the selectivity filter of the Arabidopsis NO(3)(-)/H(+) exchanger AtCLCa is essential for nitrate accumulation in planta.

  The Plant journal : for cell and molecular biology 20100901

• Metabolic response to cold and freezing of Osteospermum ecklonis overexpressing Osmyb4.

  Plant physiology and biochemistry : PPB 20100901

• Proline improves copper tolerance in chickpea (Cicer arietinum).

  Protoplasma 20100901

• The pyruvate kinase model system, a cautionary tale for the use of osmolyte perturbations to support conformational equilibria in allostery.

  Protein science : a publication of the Protein Society 20100901

• Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.

  Oncology reports 20100901

• Development of methotrexate proline prodrug to overcome resistance by MDA-MB-231 cells.

  Bioorganic & medicinal chemistry letters 20100901

• Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase.

  Bioorganic & medicinal chemistry letters 20100901

• Nitric oxide regulates stretch-induced proliferation in C2C12 myoblasts.

  Journal of muscle research and cell motility 20100901

• Mouse cytosolic sulfotransferase SULT2B1b interacts with cytoskeletal proteins via a proline/serine-rich C-terminus.

  The FEBS journal 20100901

• High frequency plant regeneration from mature seed of elite, recalcitrant Malaysian indica rice ( Oryza sativa L.) CV. MR 219.

  Acta biologica Hungarica 20100901

• Boceprevir.

  Drugs in R&D 20100901

• [Study about cardiomyocyte apoptosis in myocardial ischemic-reperfusion injury of rats and NF-κB p65, iNOS expression].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20100901

• STAT-C: a full revolution or just a step forward?

  Lancet (London, England) 20100828

• Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial.

  Lancet (London, England) 20100828

• Enamine versus oxazolidinone: what controls stereoselectivity in proline-catalyzed asymmetric aldol reactions?

  Angewandte Chemie (International ed. in English) 20100823

• Tuning the cis/trans conformer ratio of Xaa-Pro amide bonds by intramolecular hydrogen bonds: the effect on PPII helix stability.

  Angewandte Chemie (International ed. in English) 20100823

• Proline metabolism and microenvironmental stress.

  Annual review of nutrition 20100821

• Asymmetric synthesis of proline-based conformationally constrained tryptophan mimetic.

  Organic & biomolecular chemistry 20100821

• Analysis of the cholinergic pathology in the P301L tau transgenic pR5 model of tauopathy.

  Brain research 20100806

• Effects of NF-kappaB inhibitor on titanium particulate-induced inflammation in a murine model.

  The Journal of surgical research 20100801

• A novel mutation of 5alpha-steroid reductase 2 deficiency (CD 65 ALA-PRO) with severe virilization defect in a Turkish family and difficulty in gender assignment.

  European journal of pediatrics 20100801

• Biomedical research of novel biodegradable copoly(amino acid)s based on 6-aminocaproic acid and L-proline.

  Journal of biomedical materials research. Part A 20100801

• Ecophysiological responses of Abies fabri seedlings to drought stress and nitrogen supply.

  Physiologia plantarum 20100801

• The residues (35)proline and (41)cysteine of chicken IL-2 are critical for binding to chicken CD25.

  Developmental and comparative immunology 20100801

• Gas-phase conformation-specific photofragmentation of proline-containing peptide ions.

  Journal of the American Society for Mass Spectrometry 20100801

• Advantages of cocrystallization in the field of solid-state pharmaceutical chemistry: L-Proline and MnCl(2).

  European journal of medicinal chemistry 20100801

• Type I hyperprolinemia: genotype/phenotype correlations.

  Human mutation 20100801

• The mimic of type II aldolases chemistry: asymmetric synthesis of beta-hydroxy ketones by direct aldol reaction.

  Chemical biology & drug design 20100801

• Metabolic profiling strategy for discovery of nutritional biomarkers: proline betaine as a marker of citrus consumption.

  The American journal of clinical nutrition 20100801

• Impact of adenosine nucleotide translocase (ANT) proline isomerization on Ca2+-induced cysteine relative mobility/mitochondrial permeability transition pore.

  Journal of bioenergetics and biomembranes 20100801

• Involvement of NF-kappaB activation in the apoptosis induced by extracellular adenosine in human hepatocellular carcinoma HepG2 cells.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20100801

• Determination of 4-hydroxyproline-2-epimerase activity by capillary electrophoresis: A stereoselective platform for inhibitor screening of amino acid isomerases.

  Electrophoresis 20100801

• Captopril-dependent inhibition of collagen biosynthesis in cultured fibroblasts.

  Die Pharmazie 20100801

• A comparative QM/MM study of the reaction mechanism of the Hepatitis C virus NS3/NS4A protease with the three main natural substrates NS5A/5B, NS4B/5A and NS4A/4B.

  Physical chemistry chemical physics : PCCP 20100728

• Cell-mediated neuroprotection in a mouse model of human tauopathy.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100728

• Increase in surface hydrophobicity of the cataract-associated P23T mutant of human gammaD-crystallin is responsible for its dramatically lower, retrograde solubility.

  Biochemistry 20100727

• Supramolecular catalysis with extended aggregates and gels: inversion of stereoselectivity caused by self-assembly.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100726

• In vivo double and triple labeling of proteins using synthetic amino acids.

  Angewandte Chemie (International ed. in English) 20100726

• Peptide hairpin nucleation with the obligatory Type I' beta-turn Aib-DPro segment.

  Organic & biomolecular chemistry 20100721

• A hinge region cis-proline in ribonuclease A acts as a conformational gatekeeper for C-terminal domain swapping.

  Journal of molecular biology 20100716

• Exploiting a global regulator for small molecule discovery in Photorhabdus luminescens.

  ACS chemical biology 20100716

• Theoretical mechanistic study of the TBD-catalyzed intramolecular aldol reaction of ketoaldehydes.

  The Journal of organic chemistry 20100716

• Synthesis of all-L cyclic tetrapeptides using pseudoprolines as removable turn inducers.

  Organic letters 20100716

• The arbuscular mycorrhizal symbiosis enhances the photosynthetic efficiency and the antioxidative response of rice plants subjected to drought stress.

  Journal of plant physiology 20100715

• Efficient asymmetric organocatalytic formation of erythrose and threose under aqueous conditions.

  Chemical communications (Cambridge, England) 20100714

• Regioselective synthesis and in vitro anticancer activity of 4-aza-podophyllotoxin derivatives catalyzed by L-proline.

  Journal of combinatorial chemistry 20100712

• Chirally functionalized hollow nanospheres containing L-prolinamide: synthesis and asymmetric catalysis.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100712

• Studies on the catalytic mechanism of a glutamic peptidase.

  The Journal of biological chemistry 20100709

• The elusive enamine intermediate in proline-catalyzed aldol reactions: NMR detection, formation pathway, and stabilization trends.

  Angewandte Chemie (International ed. in English) 20100705

• The p85beta regulatory subunit of PI3K serves as a substrate for PTEN protein phosphatase activity during insulin mediated signaling.

  Biochemical and biophysical research communications 20100702

• Synthesis of all-carbon, quaternary center-containing cyclohexenones through an organocatalyzed, multicomponent coupling.

  Organic letters 20100702

• Salicylic acid reduces napropamide toxicity by preventing its accumulation in rapeseed (Brassica napus L.).

  Archives of environmental contamination and toxicology 20100701

• P53 codon 72 and HER2 codon 655 polymorphisms in Turkish breast cancer patients.

  DNA and cell biology 20100701

• Pro variant of TP53 Arg72Pro contributes to esophageal squamous cell carcinoma risk: evidence from a meta-analysis.

  European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20100701

• Screening the bio-safety of wheat produced from pretreated grains to enhance tolerance against drought using physiological and spectroscopic methods.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100701

• Glutamine: precursor or nitrogen donor for citrulline synthesis?

  American journal of physiology. Endocrinology and metabolism 20100701

• Potentiation of morphine antiallodynic efficacy by ACPT-III, a group III metabotropic glutamate receptor agonist, in rat spinal nerve ligation-induced neuropathic pain.

  Pharmacology, biochemistry, and behavior 20100701

• Solid-state nitrogen-14 nuclear magnetic resonance enhanced by dynamic nuclear polarization using a gyrotron.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20100701

• Enhancing the thermostability of alpha-glucosidase from Thermoanaerobacter tengcongensis MB4 by single proline substitution.

  Journal of bioscience and bioengineering 20100701

• Glutamate kinase from Thermotoga maritima: characterization of a thermophilic enzyme for proline biosynthesis.

  Extremophiles : life under extreme conditions 20100701

• Excitement grows for potential revolution in hepatitis C virus treatment.

  Nature reviews. Drug discovery 20100701

• Inheritance patterns and phenotypic features of myofibrillar myopathy associated with a BAG3 mutation.

  Neuromuscular disorders : NMD 20100701

• Development of acetaminophen proline prodrug.

  Bioorganic & medicinal chemistry letters 20100701

• Inhibition of prolyl oligopeptidase with a synthetic unnatural dipeptide.

  Bioorganic & medicinal chemistry 20100701

• In vivo and In vitro effect of a nutrient mixture on human hepatocarcinoma cell line SK-HEP-1.

  Experimental oncology 20100701

• Effect of glyprolines on homeostasis of gastric mucosa in rats with stress ulcers.

  Bulletin of experimental biology and medicine 20100701

• Brucine N-oxide-catalyzed Morita-Baylis-Hillman reaction of vinyl ketones: a mechanistic implication of dual catalyst system with proline.

  Organic & biomolecular chemistry 20100628

• A cyclopeptide-derived molecular cage for sulfate ions that closes with a click.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100625

• Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.

  Cell 20100625

• Direct catalytic asymmetric synthesis of highly functionalized tetronic acids/tetrahydro-isobenzofuran-1,5-diones via combination of cascade three-component reductive alkylations and Michael-aldol reactions.

  Organic & biomolecular chemistry 20100621

• Solution structure of a novel Cdc42 binding module of Bem1 and its interaction with Ste20 and Cdc42.

  The Journal of biological chemistry 20100618

• Y65C missense mutation in the WW domain of the Golabi-Ito-Hall syndrome protein PQBP1 affects its binding activity and deregulates pre-mRNA splicing.

  The Journal of biological chemistry 20100618

• Enantioselective synthesis of syn/anti-1,3-amino alcohols via proline-catalyzed sequential alpha-aminoxylation/alpha-amination and Horner-Wadsworth-Emmons olefination of aldehydes.

  Organic letters 20100618

• Synthesis of 2-trifluoromethyl-1,3-oxazolidines as hydrolytically stable pseudoprolines.

  The Journal of organic chemistry 20100618

• Influence of glucose-templated proline mimetics on the beta-turn conformation of the peptide fragment Ac-Leu-D-Phe-Pro-Val-NMe2 found in Gramicidin S.

  Carbohydrate research 20100616

• Glucocerebrosidase gene L444P mutation is a risk factor for Parkinson's disease in Chinese population.

  Movement disorders : official journal of the Movement Disorder Society 20100615

• Metal accumulation and its effects in relation to biochemical response of vegetables irrigated with metal contaminated water and wastewater.

  Journal of hazardous materials 20100615

• Tyrosine hydroxylase deficiency in three Greek patients with a common ancestral mutation.

  Movement disorders : official journal of the Movement Disorder Society 20100615

• Purification and characterization of Put1p from Saccharomyces cerevisiae.

  Archives of biochemistry and biophysics 20100615

• The carboxyl-terminal segment of apolipoprotein A-V undergoes a lipid-induced conformational change.

  Biochemistry 20100615

• Solid-state dynamic nuclear polarization at 263 GHz: spectrometer design and experimental results.

  Physical chemistry chemical physics : PCCP 20100614

• 2H-DNP-enhanced 2H-13C solid-state NMR correlation spectroscopy.

  Physical chemistry chemical physics : PCCP 20100614

• Extended ischemia prevents HIF1alpha degradation at reoxygenation by impairing prolyl-hydroxylation: role of Krebs cycle metabolites.

  The Journal of biological chemistry 20100611

• Unusual reversal of enantioselectivity in the proline-mediated alpha-amination of aldehydes induced by tertiary amine additives.

  Journal of the American Chemical Society 20100609

• Elimination of a cis-proline-containing loop and turn optimization stabilizes a protein and accelerates its folding.

  Journal of molecular biology 20100604

• Influence of arbuscular mycorrhiza on lipid peroxidation and antioxidant enzyme activity of maize plants under temperature stress.

  Mycorrhiza 20100601

• D-Serine metabolism in C6 glioma cells: Involvement of alanine-serine-cysteine transporter (ASCT2) and serine racemase (SRR) but not D-amino acid oxidase (DAO).

  Journal of neuroscience research 20100601

• Identification and expression analysis of a novel CW-type zinc finger protein MORC2 in cancer cells.

  Anatomical record (Hoboken, N.J. : 2007) 20100601

• Preclinical characterization of the antiviral activity of SCH 900518 (narlaprevir), a novel mechanism-based inhibitor of hepatitis C virus NS3 protease.

  Antimicrobial agents and chemotherapy 20100601

• New directly acting antivirals for hepatitis C: potential for interaction with antiretrovirals.

  The Journal of antimicrobial chemotherapy 20100601

• Lead and other elemental content of normal and Erwinia carotovora infected Amorphallus konjac corms.

  Bulletin of environmental contamination and toxicology 20100601

• The application of the yeast N-acetyltransferase MPR1 gene and the proline analogue L-azetidine-2-carboxylic acid as a selectable marker system for plant transformation.

  Journal of experimental botany 20100601

• Proline impairs energy metabolism in cerebral cortex of young rats.

  Metabolic brain disease 20100601

• Peroxisome proliferator-activated receptor gamma polymorphism and periodontitis in pregnant Japanese women.

  Journal of periodontology 20100601

• Functional analysis of a novel Cys2/His2-type zinc finger protein involved in salt tolerance in rice.

  Journal of experimental botany 20100601

• Physiological, biochemical and growth responses of lady's finger (Abelmoschus esculentus L.) plants as affected by Cd contaminated soil.

  Bulletin of environmental contamination and toxicology 20100601

• Recreational drugs, 3,4-Methylenedioxymethamphetamine(MDMA), 3,4-methylenedioxyamphetamine (MDA) and diphenylprolinol, inhibit neurite outgrowth in PC12 cells.

  The Journal of toxicological sciences 20100601

• Alternatives to dimethylsulfoxide for serum-free cryopreservation of human mesenchymal stem cells.

  The International journal of artificial organs 20100601

• Properties of the TRPML3 channel pore and its stable expansion by the Varitint-Waddler-causing mutation.

  The Journal of biological chemistry 20100528

• A chiral solvent effect in asymmetric organocatalysis.

  Organic letters 20100521

• Sequence determinants of compaction in intrinsically disordered proteins.

  Biophysical journal 20100519

• Folding of class A beta-lactamases is rate-limited by peptide bond isomerization and occurs via parallel pathways.

  Biochemistry 20100518

• Thermodynamic consequences of incorporating 4-substituted proline derivatives into a small helical protein.

  Biochemistry 20100518

• MLT-10 defines a family of DUF644 and proline-rich repeat proteins involved in the molting cycle of Caenorhabditis elegans.

  Molecular biology of the cell 20100515

• Development of a photothermal absorbance detector for use with microfluidic devices.

  Analytical chemistry 20100515

• Molecular structure of amyloid fibrils formed by residues 127 to 147 of the human prion protein.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100510

• Synthesis of notoamide J: a potentially pivotal intermediate in the biosynthesis of several prenylated indole alkaloids.

  The Journal of organic chemistry 20100507

• Racemization-free synthesis of (S)-(+)-tylophorine from L-proline by radical cyclization.

  Organic letters 20100507

• Molecularly imprinted polymer-based chemiluminescence array sensor for the detection of proline.

  Analytica chimica acta 20100507

• Arbuscular mycorrhizal fungi, Bacillus cereus, and Candida parapsilosis from a multicontaminated soil alleviate metal toxicity in plants.

  Microbial ecology 20100501

• Differential levels of transcription of p53-regulated genes by the arginine/proline polymorphism: p53 with arginine at codon 72 favors apoptosis.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100501

• Lead bioaccumulation potential of an aquatic macrophyte Najas indica are related to antioxidant system.

  Bioresource technology 20100501

• Role of glycine residues highly conserved in the S2-S3 linkers of domains I and II of voltage-gated calcium channel alpha(1) subunits.

  Biochimica et biophysica acta 20100501

• Ponsin interacts with Nck adapter proteins: implications for a role in cytoskeletal remodelling during differentiation of skeletal muscle cells.

  European journal of cell biology 20100501

• L-Proline induces differentiation of ES cells: a novel role for an amino acid in the regulation of pluripotent cells in culture.

  American journal of physiology. Cell physiology 20100501

• Antioxidant and antiacetylcholinesterase activities of chard (Beta vulgaris L. var. cicla).

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100501

• L-Proline as a modulator of ectodermal differentiation in ES cells. Focus on 'L-Proline induces differentiation of ES cells: a novel role for an amino acid in the regulation of pluripotent cells in culture.

  American journal of physiology. Cell physiology 20100501

• Dissecting the M phase-specific phosphorylation of serine-proline or threonine-proline motifs.

  Molecular biology of the cell 20100501

• Overexpression of an ERF transcription factor TSRF1 improves rice drought tolerance.

  Plant biotechnology journal 20100501

• Biochemical and physiological responses of rice (Oryza sativa L.) grown on different sewage sludge amendments rates.

  Bulletin of environmental contamination and toxicology 20100501

• Enantioseparation of amino acids and alpha-hydroxy acids on ligand-exchange continuous beds by capillary electrochromatography.

  Electrophoresis 20100501

• First appraisal of brain pathology owing to A30P mutant alpha-synuclein.

  Annals of neurology 20100501

• Residue length and solvation model dependency of elastinlike polypeptides.

  Physical review. E, Statistical, nonlinear, and soft matter physics 20100501

• Effect of glycosylation on cis/trans isomerization of prolines in IgA1-hinge peptide.

  Journal of the American Chemical Society 20100428

• The role of isolated active centres in high-performance bioinspired selective oxidation catalysts.

  Chemical communications (Cambridge, England) 20100428

• Identification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxins.

  The Journal of biological chemistry 20100423

• Proline-containing cyclopeptides from the marine sponge Phakellia fusca.

  Journal of natural products 20100423

• Spectroscopic and DFT study on the interaction system of vanadium with L-proline in aqueous solution.

  The journal of physical chemistry. A 20100422

• Assembly pathway of a designed alpha-helical protein fiber.

  Biophysical journal 20100421

• Oligoproline helices as structurally defined scaffolds for oligomeric G protein-coupled receptor ligands.

  Organic & biomolecular chemistry 20100421

• Benzyl prolinate derivatives as novel selective KCC2 blockers.

  Bioorganic & medicinal chemistry letters 20100415

• The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir: a change in direction in the search for a second generation HCV NS3 protease inhibitor.

  Bioorganic & medicinal chemistry letters 20100415

• Exogenous proline effects on photosynthetic performance and antioxidant defense system of young olive tree.

  Journal of agricultural and food chemistry 20100414

• Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons.

  The Journal of biological chemistry 20100409

• Adsorption of proline and glycine on the TiO2(110) surface: a density functional theory study.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20100406

• Enantioselective organocatalytic mannich reactions with autocatalysts and their mimics.

  The Journal of organic chemistry 20100402

• Effect of excess iron and copper on physiology of aquatic plant Spirodela polyrrhiza (L.) Schleid.

  Environmental toxicology 20100401

• Antioxidative responses related to H(2)O(2) depletion in Hypnum plumaeforme under the combined stress induced by Pb and Ni.

  Environmental monitoring and assessment 20100401

• Conformational preferences and prolyl cis-trans isomerization of phosphorylated Ser/Thr-Pro motifs.

  Biopolymers 20100401

• The first Italian family with tibial muscular dystrophy caused by a novel titin mutation.

  Journal of neurology 20100401

• Investigation of uranium accumulation potential and biochemical responses of an aquatic weed Hydrilla verticillata (L.f.) Royle.

  Bioresource technology 20100401

• Pro-205 of large hepatitis delta antigen and Pro-62 of major hepatitis B surface antigen influence the assembly of different genotypes of hepatitis D virus.

  The Journal of general virology 20100401

• Inhibition of CD26/DPP IV attenuates ischemia/reperfusion injury in orthotopic mouse lung transplants: the pivotal role of vasoactive intestinal peptide.

  Peptides 20100401

• Different effects of scopolamine and inhibition of prolyl oligopeptidase on mnemonic and motility functions of young and 8- to 9-month-old rats in the radial-arm maze.

  Basic & clinical pharmacology & toxicology 20100401

• Misincorporation of the proline homologue Aze (azetidine-2-carboxylic acid) into recombinant myelin basic protein.

  Phytochemistry 20100401

• Involvement of system A in the retina-to-blood transport of l-proline across the inner blood-retinal barrier.

  Experimental eye research 20100401

• The proline-rich domain of TonB possesses an extended polyproline II-like conformation of sufficient length to span the periplasm of Gram-negative bacteria.

  Protein science : a publication of the Protein Society 20100401

• Species differences in expression pattern of arginase isoenzymes and differential effects of arginase inhibition on collagen synthesis in human and rat pulmonary fibroblasts.

  Naunyn-Schmiedeberg's archives of pharmacology 20100401

• Major differences in the proportion of amino acid fiber types transmitting taste information from oral and extraoral regions in the channel catfish.

  Journal of neurophysiology 20100401

• Mutations in the hyperosmotic stress-responsive mitochondrial BASIC AMINO ACID CARRIER2 enhance proline accumulation in Arabidopsis.

  Plant physiology 20100401

• Prolyl 4-hydroxylase.

  Critical reviews in biochemistry and molecular biology 20100401

• Orally active and brain permeable proline amides as highly selective 5HT2c agonists for the treatment of obesity.

  Bioorganic & medicinal chemistry letters 20100401

• Potent ketoamide inhibitors of HCV NS3 protease derived from quaternized P1 groups.

  Bioorganic & medicinal chemistry letters 20100401

• Inhibition of Escherichia coli glycosyltransferase MurG and Mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics.

  Bioorganic & medicinal chemistry 20100401

• Kinetic-based high-throughput screening assay to discover novel classes of macrophage migration inhibitory factor inhibitors.

  Journal of biomolecular screening 20100401

• Poor outcome after liver transplantation for transthyretin amyloid neuropathy in a family with an Ala36Pro transthyretin mutation: case report.

  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20100401

• Augmented currents of an HCN2 variant in patients with febrile seizure syndromes.

  Annals of neurology 20100401

• New insight into mode of action of Colostrinin.

  The journal of nutrition, health & aging 20100401

• Metal cation dependence of interactions with amino acids: bond energies of Rb+ to Gly, Ser, Thr, and Pro.

  The journal of physical chemistry. B 20100325

• Structural basis for the superior activity of the large isoform of snow flea antifreeze protein.

  Biochemistry 20100323

• 2D random organization of racemic amino acid monolayers driven by nanoscale adsorption footprints: proline on Cu(110).

  Angewandte Chemie (International ed. in English) 20100322

• Novel thiourea-amine bifunctional catalysts for asymmetric conjugate addition of ketones/aldehydes to nitroalkenes: rational structural combination for high catalytic efficiency.

  Organic & biomolecular chemistry 20100321

• Chemical scale studies of the Phe-Pro conserved motif in the cys loop of Cys loop receptors.

  The Journal of biological chemistry 20100319

• The proline-rich N-terminal domain of G18 exhibits a novel G protein regulatory function.

  The Journal of biological chemistry 20100319

• Mechanism for the selective interaction of C-terminal Eps15 homology domain proteins with specific Asn-Pro-Phe-containing partners.

  The Journal of biological chemistry 20100319

• Enantiomerically pure polyheterocyclic spiro-beta-lactams from trans-4-hydroxy-L-proline.

  The Journal of organic chemistry 20100319

• Early behavioural markers of disease in P301S tau transgenic mice.

  Behavioural brain research 20100317

• Chiral silver amide-catalyzed enantioselective [3 + 2] cycloaddition of alpha-aminophosphonates with olefins.

  Journal of the American Chemical Society 20100317

• Effects of cadmium stress on growth and anti-oxidative systems in Achnatherum inebrians symbiotic with Neotyphodium gansuense.

  Journal of hazardous materials 20100315

• Cadmium has contrasting effects on polyethylene glycol-sensitive and resistant cell lines in the Mediterranean halophyte species Atriplex halimus L.

  Journal of plant physiology 20100315

• A noncatalytic domain of glycogen synthase kinase-3 (GSK-3) is essential for activity.

  The Journal of biological chemistry 20100312

• Switching catalysis from hydrolysis to perhydrolysis in Pseudomonas fluorescens esterase.

  Biochemistry 20100309

• Efficient one-pot synthesis of spirooxindole derivatives catalyzed by L-proline in aqueous medium.

  Journal of combinatorial chemistry 20100308

• Multicomponent asymmetric reactions mediated by proline lithium salt.

  Organic & biomolecular chemistry 20100307

• Identification of a novel inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1)-mediated methylation of histone H3 Arg-17.

  The Journal of biological chemistry 20100305

• Synthesis of syn-gamma-amino-beta-hydroxyphosphonates by reduction of beta-ketophosphonates derived from L-proline and L-serine.

  Molecules (Basel, Switzerland) 20100304

• Intramolecular anodic olefin coupling reactions and the synthesis of cyclic amines.

  Journal of the American Chemical Society 20100303

• Copper-catalyzed N-arylation of amides using (S)-N-methylpyrrolidine-2-carboxylate as the ligand.

  Molecules (Basel, Switzerland) 20100302

• Kinetics of Zn(2+)-induced brain type creatine kinase unfolding and aggregation.

  Applied biochemistry and biotechnology 20100301

• L-Proline transport into renal OK epithelial cells: a second renal proline transport system is induced by amino acid deprivation.

  Amino acids 20100301

• Synthesis of proline-derived dipeptides and their catalytic enantioselective direct aldol reactions: catalyst, solvent, additive and temperature effects.

  Amino acids 20100301

• Proline reduces the binding of transcriptional regulator ArgR to upstream of argB in Corynebacterium glutamicum.

  Applied microbiology and biotechnology 20100301

• Brassinosteroids protect Lycopersicon esculentum from cadmium toxicity applied as shotgun approach.

  Protoplasma 20100301

• In vitro biochemical evaluation of cadmium tolerance mechanism in callus and seedlings of Brassica juncea.

  Protoplasma 20100301

• Overexpression of soybean ubiquitin-conjugating enzyme gene GmUBC2 confers enhanced drought and salt tolerance through modulating abiotic stress-responsive gene expression in Arabidopsis.

  Plant molecular biology 20100301

• Differences in growth and physiological traits of two poplars originating from different altitudes as affected by UV-B radiation and nutrient availability.

  Physiologia plantarum 20100301

• A cryptic role of a glycolytic-gluconeogenic enzyme (aldolase) in amino acid transporter turnover in Aspergillus nidulans.

  Fungal genetics and biology : FG & B 20100301

• Retinal metabolic state of the proline-23-histidine rat model of retinitis pigmentosa.

  American journal of physiology. Cell physiology 20100301

• Prediction of Xaa-Pro peptide bond conformation from sequence and chemical shifts.

  Journal of biomolecular NMR 20100301

• Isolation of a new class of cysteine-glycine-proline-rich beta-proteins (beta-keratins) and their expression in snake epidermis.

  Journal of anatomy 20100301

• Pyrroline-5-carboxylate synthase and proline biosynthesis: from osmotolerance to rare metabolic disease.

  Protein science : a publication of the Protein Society 20100301

• Towards the second generation of Boceprevir: Dithianes as an alternative P2 substituent for 2,2-dimethyl cycloproyl proline in HCV NS3 protease inhibitors.

  Bioorganic & medicinal chemistry letters 20100301

• Population description and its role in the interpretation of genetic association.

  Human genetics 20100301

• Association of TP53 codon 72 polymorphism with cervical cancer risk in Chinese women.

  Cancer genetics and cytogenetics 20100301

• L-Valine and L-Proline--solid-state IR-LD spectroscopic study.

  Protein and peptide letters 20100301

• Effects of water deficit stress on growth, water relations and osmolyte accumulation in Medicago truncatula and M. laciniata populations.

  Comptes rendus biologies 20100301

• [Effects of the site-directed mutagenesis at nsP2-726Pro on replicon vector derived from XJ-160 virus].

  Bing du xue bao = Chinese journal of virology 20100301

• New insight into the mechanism of action of the temporin antimicrobial peptides.

  Biochemistry 20100223

• Inverse correlation of thermal lability and conversion efficiency for five prion protein polymorphic variants.

  Biochemistry 20100223

• Helix propensities of conformationally restricted amino acids. Non-natural substitutes for helix breaking proline and helix forming alanine.

  Organic & biomolecular chemistry 20100221

• Evaluation of stereochemically dense morpholine-based scaffolds as proline surrogates in beta-turn peptides.

  Organic & biomolecular chemistry 20100221

• Amino acid residues critical for endoplasmic reticulum export and trafficking of platelet-activating factor receptor.

  The Journal of biological chemistry 20100219

• A facile and efficient synthesis of 3,3-dimethyl isopropylidene proline from (+)-3-carene.

  The Journal of organic chemistry 20100219

• Pharmacological and phytochemical study on a Sisymbrium officinale Scop. extract.

  Journal of ethnopharmacology 20100217

• Effects of interdomain tether length and flexibility on the kinetics of intramolecular electron transfer in human sulfite oxidase.

  Biochemistry 20100216

• Differential phospholipid binding of alpha-synuclein variants implicated in Parkinson's disease revealed by solution NMR spectroscopy.

  Biochemistry 20100209

• Role of prolyl cis/trans isomers in cyclophilin-assisted Pseudomonas syringae AvrRpt2 protease activation.

  Biochemistry 20100209

• Assembly of substituted phenothiazines by a sequentially controlled CuI/ L-proline-catalyzed cascade C-S and C-N bond formation.

  Angewandte Chemie (International ed. in English) 20100208

• Inhibition of immune-mediated concanavalin a-induced liver damage by free-radical scavengers.

  Digestive diseases and sciences 20100201

• Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers.

  Journal of cancer research and clinical oncology 20100201

• Association between transforming growth factor beta1 polymorphisms and left ventricle hypertrophy in essential hypertensive subjects.

  Molecular and cellular biochemistry 20100201

• Over-expression of ThpI from Choristoneura fumiferana enhances tolerance to cold in Arabidopsis.

  Molecular biology reports 20100201

• Tolerance of arsenate-induced stress in Aspergillus niger, a possible candidate for bioremediation.

  Ecotoxicology and environmental safety 20100201

• The pandemic 2009 (H1N1) swine influenza virus is mild compared to the pandemic 1918 (H1N1) virus because of a proline-to-serine substitution in the receptor-binding site of its hemagglutinin - a hypothesis.

  Medical hypotheses 20100201

• Substitution of serine for proline in the active center of type 2 iodothyronine deiodinase substantially alters its in vitro biochemical properties with dithiothreitol but not its function in intact cells.

  Endocrinology 20100201

• Slightly modifying pseudoproline dipeptides incorporation strategy enables solid phase synthesis of a 54 AA fragment of caveolin-1 encompassing the intramembrane domain.

  Journal of peptide science : an official publication of the European Peptide Society 20100201

• Heterocycle-substituted proline dipeptides as potent VLA-4 antagonists.

  Bioorganic & medicinal chemistry letters 20100201

• Interaction of maternal peroxisome proliferator-activated receptor gamma2 Pro12Ala polymorphism with fetal sex affects maternal glycemic control during pregnancy.

  Pharmacogenetics and genomics 20100201

• Proline: a multifunctional amino acid.

  Trends in plant science 20100201

• Physiological responses of Norway spruce (Picea abies) seedlings to drought stress.

  Tree physiology 20100201

• Interaction and structural modification of topoisomerase IIalpha by peptidyl prolyl isomerase, pin1: an in silico study.

  Protein and peptide letters 20100201

• Evaluation of synthetic cell-penetrating peptides, Pro-rich peptide and octaargine derivatives, as adenovirus vector carrier.

  Protein and peptide letters 20100201

• Proline cis/trans-isomerase Pin1 regulates peroxisome proliferator-activated receptor gamma activity through the direct binding to the activation function-1 domain.

  The Journal of biological chemistry 20100129

• The structure of the proline utilization a proline dehydrogenase domain inactivated by N-propargylglycine provides insight into conformational changes induced by substrate binding and flavin reduction.

  Biochemistry 20100126

• Substrate-dependent nonlinear effects in proline-thiourea-catalyzed aldol reactions: unraveling the role of the thiourea co-catalyst.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100125

• Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.

  The Journal of biological chemistry 20100122

• Splicing of the mycobacteriophage Bethlehem DnaB intein: identification of a new mechanistic class of inteins that contain an obligate block F nucleophile.

  The Journal of biological chemistry 20100122

• Rapid two-step synthesis of drug-like polycyclic substances by sequential multi-catalysis cascade reactions.

  Organic & biomolecular chemistry 20100121

• P4 capped amides and lactams as HCV NS3 protease inhibitors with improved potency and DMPK profile.

  Bioorganic & medicinal chemistry letters 20100115

• L-proline-catalyzed three-component domino [3+2+1] annulation for the regio- and diastereoselective synthesis of highly substituted thienothiopyrans containing three or four stereocenters.

  The Journal of organic chemistry 20100115

• Evaluation of the frequency of TP53 gene codon 72 polymorphisms in Iranian patients with endometrial cancer.

  Cancer genetics and cytogenetics 20100115

• In vitro reconstitution of the first steps of anatoxin-a biosynthesis in Oscillatoria PCC 6506: from free L-proline to acyl carrier protein bound dehydroproline.

  Biochemistry 20100112

• Regulating alternative lifestyles in entomopathogenic bacteria.

  Current biology : CB 20100112

• Host-pathogen interactions: proline gives insect pathogens the green light.

  Current biology : CB 20100112

• Evaluation of the influence of proline, hydroxyproline or pyrrolidine in the presence of sodium nitrite on N-nitrosamine formation when heating cured meat.

  Analytica chimica acta 20100111

• Proline is not uniquely capable of providing the pivot point for domain swapping in 2G12, a broadly neutralizing antibody against HIV-1.

  The Journal of biological chemistry 20100108

• Prolinoamino acids as tools to build bifunctionalized, stable beta-turns in water.

  Chembiochem : a European journal of chemical biology 20100104

• Cu(I)/L-proline-catalyzed coupling of substituted 3-iodoprop-2-en-1-ols with 1-alkynes and subsequent cyclization: a convenient approach for synthesizing polysubstituted furans.

  Chemistry, an Asian journal 20100104

• Intracerebroventricular injection of L-proline and D-proline induces sedative and hypnotic effects by different mechanisms under an acute stressful condition in chicks.

  Amino acids 20100101

• CAT C-262T and GPX1 Pro198Leu polymorphisms in a Turkish population.

  Molecular biology reports 20100101

• Orexin receptor antagonism prevents transcriptional and behavioral plasticity resulting from stimulant exposure.

  Neuropharmacology 20100101

• The physiological response and sub-cellular localization of lead and cadmium in Iris pseudacorus L.

  Ecotoxicology (London, England) 20100101

• Nitrophenolates spray can alter boll abscission rate in cotton through enhanced peroxidase activity and increased ascorbate and phenolics levels.

  Journal of plant physiology 20100101

• Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion.

  Cardiovascular research 20100101

• Conversion of phenol to glutamate and proline in Corynebacterium glutamicum is regulated by transcriptional regulator ArgR.

  Applied microbiology and biotechnology 20100101

• The PPAR-gamma Pro12Ala polymorphism associates with weight gain during GH-treatment in short children born small for gestational age.

  European journal of endocrinology 20100101

• Systemin-dependent salinity tolerance in tomato: evidence of specific convergence of abiotic and biotic stress responses.

  Physiologia plantarum 20100101

• Effect of ploidy levels on the activities of delta(1)-pyrroline-5-carboxylate synthetase, superoxide dismutase and peroxidase in Cenchrus species grown under water stress.

  Plant physiology and biochemistry : PPB 20100101

• SLC/CCR7 stimulates the proliferation of BMDCs by the pNF-kappaB p65 pathway.

  Anatomical record (Hoboken, N.J. : 2007) 20100101

• L-Proline reduces IgG dimer content and enhances the stability of intravenous immunoglobulin (IVIG) solutions.

  Biologicals : journal of the International Association of Biological Standardization 20100101

• Primary sequence and site-selective hydroxylation of prolines in isoforms of a major peanut allergen protein Ara h 2.

  Protein science : a publication of the Protein Society 20100101

• Salt affects plant Cd-stress responses by modulating growth and Cd accumulation.

  Planta 20100101

• Mitochondria sense with different kinetics the calcium entering into HeLa cells through calcium channels CALHM1 and mutated P86L-CALHM1.

  Biochemical and biophysical research communications 20100101

• The effects of Se phytotoxicity on the antioxidant systems of leaf tissues in barley (Hordeum vulgare L.) seedlings.

  Plant physiology and biochemistry : PPB 20100101

• Glycosylated PROLI/NO derivatives as nitric oxide prodrugs.

  Organic letters 20100101

• Hypoxia activates heparanase expression in an NF-kappaB dependent manner.

  Oncology reports 20100101

• Comparison of influence of carmustine and new proline analog of nitrosourea on antioxidant system in breast carcinoma cells (MCF-7).

  Drug and chemical toxicology 20100101

• Proline-rich domain plays a crucial role in extracellular stimuli-responsive translocation of a Cdc42 guanine nucleotide exchange factor, FGD1.

  Biological & pharmaceutical bulletin 20100101

• Simultaneous determination of tetracaine, proline, and enoxacin in human urine by CE with ECL detection.

  Journal of chromatographic science 20100101

• CALHM1 P86L polymorphism is a risk factor for Alzheimer's disease in the Chinese population.

  Journal of Alzheimer's disease : JAD 20100101

• JSCTR-CTR commentary. What is the function of proline in the collagen molecule?

  Connective tissue research 20100101

• Stachydrine, a major constituent of the Chinese herb leonurus heterophyllus sweet, ameliorates human umbilical vein endothelial cells injury induced by anoxia-reoxygenation.

  The American journal of Chinese medicine 20100101

• Enhancement of ornithine production in proline-supplemented Corynebacterium glutamicum by ornithine cyclodeaminase.

  Journal of microbiology and biotechnology 20100101

• Staphylococcal PknB as the first prokaryotic representative of the proline-directed kinases.

  PloS one 20100101

• 'Prion-like' propagation of mouse and human tau aggregates in an inducible mouse model of tauopathy.

  Neuro-degenerative diseases 20100101

• CALHM1 P86L polymorphism is associated with late-onset Alzheimer's disease in a recessive model.

  Journal of Alzheimer's disease : JAD 20100101

• Lack of implication for CALHM1 P86L common variation in Italian patients with early and late onset Alzheimer's disease.

  Journal of Alzheimer's disease : JAD 20100101

• A flow-through electrochemiluminescence sensor for salt stress on rice plants.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20100101

• Efficacy of a spray compound containing a pool of collagen precursor synthetic aminoacids (l-proline, l-leucine, l-lysine and glycine) combined with sodium hyaluronate to manage chemo/radiotherapy-induced oral mucositis: preliminary data of an open trial.

  International journal of immunopathology and pharmacology 20100101

• Quantification of water stress-induced osmotic adjustment and proline accumulation for Arabidopsis thaliana molecular genetic studies.

  Methods in molecular biology (Clifton, N.J.) 20100101

• Methods for determination of proline in plants.

  Methods in molecular biology (Clifton, N.J.) 20100101

• Non-redundant functions of two proline dehydrogenase isoforms in Arabidopsis.

  BMC plant biology 20100101

• Ameliorative effect of a hippocampal metabotropic glutamate- receptor agonist on histamine H1 receptor antagonist-induced memory deficit in rats.

  Journal of pharmacological sciences 20100101

• Generalized connective tissue disease in Crtap-/- mouse.

  PloS one 20100101

• Antiviral properties of structural fragments of the peptide Selank.

  Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20100101

• [Effect of nitroderivatives of fullerene C60 on amyloid fibrils of Abeta(1-42) peptide of the brain and muscle X-protein].

  Biofizika 20100101

• Assessment of the influence of different sample processing and cold storage duration on plant free proline content analyses.

  Phytochemical analysis : PCA 20100101

• Cd uptake in rice cultivars treated with organic acids and EDTA.

  Journal of environmental sciences (China) 20100101

• On the cusp of change: new therapeutic modalities for HCV.

  Annals of hepatology 20100101

• [Protective antithrombotic effects of proline-containing peptides in the animal body subjected to stress].

  Izvestiia Akademii nauk. Seriia biologicheskaia 20100101

• Antioxidative responses of Elodea nuttallii (Planch.) H. St. John to short-term iron exposure.

  Plant physiology and biochemistry : PPB 20100101

• Amyloid-β induces cyclooxygenase-2 and PGE2 release in human astrocytes in NF-κ B dependent manner.

  Journal of Alzheimer's disease : JAD 20100101

• Medicinial chemistry. Preface.

  Progress in medicinal chemistry 20100101

• The Journey to the Discovery of Boceprevir: an NS3-NS4 HCV protease inhibitor for the treatment of chronic hepatitis C.

  Progress in medicinal chemistry 20100101

• Simultaneous determination of proline and pipemidic acid in human urine by capillary electrophoresis with electrochemiluminescence detection.

  Journal of clinical laboratory analysis 20100101

• The intriguing cyclophilin A-HIV-1 Vpr interaction: prolyl cis/trans isomerisation catalysis and specific binding.

  BMC structural biology 20100101

• Multicopy proC in Streptomyces coelicolor A3(2) elicits a transient production of prodiginines, while proC deletion does not yield a proline auxotroph.

  Journal of molecular microbiology and biotechnology 20100101

• Transforming growth factor-β-1 polymorphisms are infrequent but exist at selected loci in oral submucous fibrosis.

  Indian journal of dental research : official publication of Indian Society for Dental Research 20100101

• A mutational analysis and molecular dynamics simulation of quinolone resistance proteins QnrA1 and QnrC from Proteus mirabilis.

  BMC structural biology 20100101

• Proline and glycinebetaine ameliorated NaCl stress via scavenging of hydrogen peroxide and methylglyoxal but not superoxide or nitric oxide in tobacco cultured cells.

  Bioscience, biotechnology, and biochemistry 20100101

• The development and evaluation of single cell suspension from wheat and barley as a model system; a first step towards functional genomics application.

  BMC plant biology 20100101

• Transcriptomic and metabolomic shifts in rice roots in response to Cr (VI) stress.

  BMC genomics 20100101

• Effective salt criteria in callus-cultured tomato genotypes.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20100101

• Recent biomimetic and organocatalytic syntheses of alpha-tocopherol.

  Chimia 20100101

• Histidine domain-protein tyrosine phosphatase interacts with Grb2 and GrpL.

  PloS one 20100101

• Molecular determinants of survival motor neuron (SMN) protein cleavage by the calcium-activated protease, calpain.

  PloS one 20100101

• TGF-β1 induces podocyte injury through Smad3-ERK-NF-κB pathway and Fyn-dependent TRPC6 phosphorylation.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

• Prompt arrival of antivirals against hepatitis C for HIV patients.

  AIDS reviews 20100101

• Physiological responses and detoxific mechanisms to Pb, Zn, Cu and Cd in young seedlings of Paulownia fortunei.

  Journal of environmental sciences (China) 20100101

• Toxic effects of 1-methyl-3-octylimidazolium bromide on the wheat seedlings.

  Journal of environmental sciences (China) 20100101

• Treatment of hepatitis C in 2011.

  Journal of Ayub Medical College, Abbottabad : JAMC 20100101

• Saline water irrigation effects on antioxidant defense system and proline accumulation in leaves and roots of field-grown olive.

  Journal of agricultural and food chemistry 20091223

• Influence of proline upon the folding and geometry of the WALP19 transmembrane peptide.

  Biochemistry 20091222

• Insight into the molecular switch mechanism of human Rab5a from molecular dynamics simulations.

  Biochemical and biophysical research communications 20091218

• Proline-beta(3)-amino-ester dipeptides as efficient catalysts for enantioselective direct aldol reaction in aqueous medium.

  The Journal of organic chemistry 20091218

• 4-Fluoro-2,4-methanoproline.

  Organic letters 20091217

• Functional expression of two system A glutamine transporter isoforms in rat auditory brainstem neurons.

  Neuroscience 20091215

• Activity of prolidase isoenzymes in the rat brain: subcellular and regional distribution during development.

  Brain research 20091215

• Absence of pain with hyperhidrosis: a new syndrome where vascular afferents may mediate cutaneous sensation.

  Pain 20091215

• A rapid method for the extraction, enantiomeric separation and quantification of amphetamines in hair.

  Forensic science international 20091215

• Neutrophils contain prolyl endopeptidase and generate the chemotactic peptide, PGP, from collagen.

  Journal of neuroimmunology 20091210

• 4-Aminoproline-based arginine-glycine-aspartate integrin binders with exposed ligation points: practical in-solution synthesis, conjugation and binding affinity evaluation.

  Organic & biomolecular chemistry 20091207

• L-proline-catalyzed synthesis of highly functionalized multisubstituted 1,4-dihydropyridines.

  Organic & biomolecular chemistry 20091207

• Enantioselective syntheses of alpha-Fmoc-Pbf-[2-(13)C]-L-arginine and Fmoc-[1,3-(13)C2]-L-proline and Incorporation into the neurotensin receptor 1 ligand, NT(8-13).

  The Journal of organic chemistry 20091204

• Three-dimensional loading model for periodontal ligament regeneration in vitro.

  Tissue engineering. Part C, Methods 20091201

• Toward an antitumor form of bovine pancreatic ribonuclease: the crystal structure of three noncovalent dimeric mutants.

  Biopolymers 20091201

• Beneficial effects of exogenous selenium in cucumber seedlings subjected to salt stress.

  Biological trace element research 20091201

• Reversed-phase high-performance liquid chromatographic enantioresolution of six beta-blockers using dinitrophenyl-L-Pro-N-hydroxysuccinimide ester, N-succinimidyl-(S)-2-(6-methoxynaphth-2-yl) propionate and twelve variants of Sanger's reagent as chiral derivatizing reagents.

  Biomedical chromatography : BMC 20091201

• The involvement of proline-rich 15 in early conceptus development in sheep.

  Biology of reproduction 20091201

• Confirmation of allele HLA-A*3116 found in a family of a leukaemia patient with Caucasian and Caribbean origin.

  International journal of immunogenetics 20091201

• Impact of the PPAR-gamma2 Pro12Ala polymorphism and ACE inhibitor therapy on new-onset microalbuminuria in type 2 diabetes: evidence from BENEDICT.

  Diabetes 20091201

• Loss of responses to visual but not electrical stimulation in ganglion cells of rats with severe photoreceptor degeneration.

  Journal of neurophysiology 20091201

• L-proline-catalysed facile green protocol for the synthesis and antimycobacterial evaluation of [1,4]-thiazines.

  European journal of medicinal chemistry 20091201

• Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients.

  Hepatology (Baltimore, Md.) 20091201

• Study on the interaction of levocetirizine dihydrochloride with human serum albumin by molecular spectroscopy.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20091201

• Highly sensitive determination of HCV protease inhibitors boceprevir (SCH 503034) and telaprevir (VX 950) in human plasma by LC-MS/MS.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091201

• Spironolactone attenuates experimental uremic cardiomyopathy by antagonizing marinobufagenin.

  Hypertension (Dallas, Tex. : 1979) 20091201

• Alanine aminotransferase of Trypanosoma brucei--a key role in proline metabolism in procyclic life forms.

  The FEBS journal 20091201

• The effect of microenvironmental CD40 signals on TRAIL- and drug-induced apoptosis in follicular lymphoma cells.

  Scandinavian journal of immunology 20091201

• Refinement of the clinical phenotype in musk-related congenital myasthenic syndromes.

  Neurology 20091201

• The effect of a proline residue on the rate of growth and the space group of alpha-spectrin SH3-domain crystals.

  Acta crystallographica. Section D, Biological crystallography 20091201

• Antiangiogenic properties of a nutrient mixture in a model of hemangioma.

  Experimental oncology 20091201

• [Effect of PTD-deltaPRD Foxp3 fusion protein on the mixed lymphocyte reaction in mice].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20091201

• Proline transport and stress tolerance of ammonia-insensitive mutants of the PUT4-encoded proline-specific permease in yeast.

  The Journal of general and applied microbiology 20091201

• Inhibition of Trypanosoma cruzi proline racemase affects host-parasite interactions and the outcome of in vitro infection.

  Memorias do Instituto Oswaldo Cruz 20091201

• The human alpha-lactalbumin molten globule: comparison of structural preferences at pH 2 and pH 7.

  Journal of molecular biology 20091127

• Negative evidence for stachydrine or Galeopsis ladanum L. seeds as the causal agents of coturnism after quail meat ingestion.

  Journal of agricultural and food chemistry 20091125

• Effect of chirality of L/D-proline and prochiral glycine as the linker amino acid in five-atom linked thymidinyl-(alpha-amino acid)-thymidine dimers.

  Chemical communications (Cambridge, England) 20091121

• Increased tolerance of rice to cold, drought and oxidative stresses mediated by the overexpression of a gene that encodes the zinc finger protein ZFP245.

  Biochemical and biophysical research communications 20091120

• Physiological and growth changes in micropropagated Citrus macrophylla explants due to salinity.

  Journal of plant physiology 20091115

• Increasing protein stability by improving beta-turns.

  Proteins 20091115

• Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis.

  The Journal of biological chemistry 20091113

• Chiral biphenylamide derivative: an efficient organocatalyst for the enantioselective synthesis of alpha-hydroxy phosphonates.

  Organic & biomolecular chemistry 20091107

• Proline-rich sequence recognition: I. Marking GYF and WW domain assembly sites in early spliceosomal complexes.

  Molecular & cellular proteomics : MCP 20091101

• Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions.

  Molecular & cellular proteomics : MCP 20091101

• Clonal response to cold tolerance in creeping bentgrass and role of proline-associated pentose phosphate pathway.

  Bioresource technology 20091101

• Glucose uptake in the mammalian stages of Trypanosoma cruzi.

  Molecular and biochemical parasitology 20091101

• Fragmentation of doubly-protonated Pro-His-Xaa tripeptides: formation of b(2)(2+) ions.

  Journal of the American Society for Mass Spectrometry 20091101

• Alternative splicing of ADAM15 regulates its interactions with cellular SH3 proteins.

  Journal of cellular biochemistry 20091101

• Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma-2 gene on obesity risk and leptin levels in a Tunisian population.

  Clinical biochemistry 20091101

• A novel HCV NS3 protease mutation selected by combination treatment of the protease inhibitor boceprevir and NS5B polymerase inhibitors.

  Antiviral research 20091101

• Top-down protein fragmentation by infrared multiphoton dissociation in a dual pressure linear ion trap.

  Analytical chemistry 20091101

• Discovery of novel sphingosine kinase 1 inhibitors.

  Bioorganic & medicinal chemistry letters 20091101

• Mapping the phosphorylation sites of Ulk1.

  Journal of proteome research 20091101

• Defective O-glycosylation due to a novel homozygous S129P mutation is associated with lack of fibroblast growth factor 23 secretion and tumoral calcinosis.

  The Journal of clinical endocrinology and metabolism 20091101

• Proline analogue of nitrosourea as a new cytotoxic prodrug.

  Archiv der Pharmazie 20091101

• In-source fragmentation of very labile peptides in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

  Analytical chemistry 20091101

• Ups and downs of intestinal function with prolonged fasting during aestivation in the burrowing frog, Cyclorana alboguttata.

  The Journal of experimental biology 20091101

• Polymorphism of tumor protein p53 codon 72 showed no association with oral lichen planus in Shiraz, Iran.

  The Journal of craniofacial surgery 20091101

• Can ornithine accumulation modulate abiotic stress tolerance in Arabidopsis?

  Plant signaling & behavior 20091101

• Increased production of CXCL16 in experimental and clinical heart failure: a possible role in extracellular matrix remodeling.

  Circulation. Heart failure 20091101

• Proline accumulation in plants: not only stress.

  Plant signaling & behavior 20091101

• [New antiviral agents against hepatitis C in clinical trials. Hope for a cure--but resistance problems must be overcomed].

  Lakartidningen 20091101

• A cis-proline in alpha-hemoglobin stabilizing protein directs the structural reorganization of alpha-hemoglobin.

  The Journal of biological chemistry 20091023

• Enantioselective nitro-Michael reactions catalyzed by short peptides on water.

  Organic & biomolecular chemistry 20091021

• Assembly of substituted 1H-benzimidazoles and 1,3-dihydrobenzimidazol-2-ones via CuI/L-proline catalyzed coupling of aqueous ammonia with 2-iodoacetanilides and 2-iodophenylcarbamates.

  The Journal of organic chemistry 20091016

• Exogenous proline and glycinebetaine increase antioxidant enzyme activities and confer tolerance to cadmium stress in cultured tobacco cells.

  Journal of plant physiology 20091015

• Hydrogen peroxide-induced proline and metabolic pathway of its accumulation in maize seedlings.

  Journal of plant physiology 20091015

• Overexpression of TaSTRG gene improves salt and drought tolerance in rice.

  Journal of plant physiology 20091015

• LRRK2 R1628P variant is a risk factor of Parkinson's disease among Han-Chinese from mainland China.

  Movement disorders : official journal of the Movement Disorder Society 20091015

• Direct enantioselective organocatalytic hydroxymethylation of aldehydes catalyzed by alpha,alpha-diphenylprolinol trimethylsilyl ether.

  Organic letters 20091015

• Molecular consequences of genetic variations in the glutathione peroxidase 1 selenoenzyme.

  Cancer research 20091015

• The implications of (2S,4S)-hydroxyproline 4-O-glycosylation for prolyl amide isomerization.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20091012

• PPIB mutations cause severe osteogenesis imperfecta.

  American journal of human genetics 20091009

• Quantum mechanical and NMR studies of ring puckering and cis/trans-rotameric interconversion in prolines and hydroxyprolines.

  The journal of physical chemistry. A 20091008

• Tripeptides of the type H-D-Pro-Pro-Xaa-NH2 as catalysts for asymmetric 1,4-addition reactions: structural requirements for high catalytic efficiency.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20091005

• A novel endoplasmic reticulum export signal: proline at the +2-position from the signal peptide cleavage site.

  The Journal of biological chemistry 20091002

• The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides.

  The Journal of biological chemistry 20091002

• A meta-analysis of TP53 codon 72 polymorphism and lung cancer risk: evidence from 15,857 subjects.

  Lung cancer (Amsterdam, Netherlands) 20091001

• The P561T polymorphism of the growth hormone receptor gene has an inhibitory effect on mandibular growth in young children.

  European journal of orthodontics 20091001

• HCV-NS3 inhibitors: determination of their kinetic parameters and mechanism.

  Biochimica et biophysica acta 20091001

• The proline 12 alanine substitution in the PPARgamma2 gene is associated with increased extent of coronary artery disease in men.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20091001

• Sex-related adaptive responses of Populus cathayana to photoperiod transitions.

  Plant, cell & environment 20091001

• Polymorphism of Pro12Ala in the peroxisome proliferator-activated receptor gamma2 gene in Iranian diabetic and obese subjects.

  Metabolic syndrome and related disorders 20091001

• The association of olanzapine-induced weight gain with peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism in patients with schizophrenia.

  DNA and cell biology 20091001

• The pleiotropic cell separation mutation spl1-1 is a nucleotide substitution in the internal promoter of the proline tRNACGG gene of Schizosaccharomyces pombe.

  Current genetics 20091001

• A conserved proline between domains II and III of hepatitis C virus NS5A influences both RNA replication and virus assembly.

  Journal of virology 20091001

• Abscisic acid has contrasting effects on salt excretion and polyamine concentrations of an inland and a coastal population of the Mediterranean xero-halophyte species Atriplex halimus.

  Annals of botany 20091001

• The effect of ArgR-DNA binding affinity on ornithine production in Corynebacterium glutamicum.

  Current microbiology 20091001

• Neuronal apoptosis by prolyl hydroxylation: implication in nervous system tumours and the Warburg conundrum.

  Journal of cellular and molecular medicine 20091001

• Nitric reductase-dependent nitric oxide production is involved in cold acclimation and freezing tolerance in Arabidopsis.

  Plant physiology 20091001

• Structural and mechanistic roles of three consecutive Pro residues of porcine NADH-cytochrome b(5) reductase for the binding of beta-NADH.

  Journal of bioscience and bioengineering 20091001

• Hepatitis C drug development at a crossroads.

  Hepatology (Baltimore, Md.) 20091001

• Proline and glycinebetaine confer cadmium tolerance on tobacco bright yellow-2 cells by increasing ascorbate-glutathione cycle enzyme activities.

  Bioscience, biotechnology, and biochemistry 20091001

• Further evidence for an association between mandibular height and the growth hormone receptor gene in a Japanese population.

  American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 20091001

• [Novel yeast acetyltransferase Mpr1 regulates reactive oxygen species mediated by proline metabolism].

  Seikagaku. The Journal of Japanese Biochemical Society 20091001

• Cis-trans proline isomerization effects on collagen triple-helix stability are limited.

  Journal of the American Chemical Society 20090930

• Amino acid ionic liquids as chiral ligands in ligand-exchange chiral separations.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090928

• Unraveling delta1-pyrroline-5-carboxylate-proline cycle in plants by uncoupled expression of proline oxidation enzymes.

  The Journal of biological chemistry 20090925

• PKC phosphorylation of titin's PEVK element: a novel and conserved pathway for modulating myocardial stiffness.

  Circulation research 20090925

• Titin phosphorylation: myocardial passive stiffness regulated by the intracellular giant.

  Circulation research 20090925

• Enantioselective nucleophilic addition of trimethylsilylacetylene to n-phosphinoylimines promoted by C(2)-symmetric proline-derived beta-amino alcohol.

  The Journal of organic chemistry 20090918

• Diphenylprolinol silyl ether as a catalyst in an asymmetric, catalytic, and direct michael reaction of nitroethanol with alpha,beta-unsaturated aldehydes.

  Organic letters 20090917

• Resonance Raman spectra of an O2-binding H-NOX domain reveal heme relaxation upon mutation.

  Biochemistry 20090915

• Synthesis and biological evaluation of 4-fluoroproline and 4-fluoropyrrolidine-2-acetic acid derivatives as new GABA uptake inhibitors.

  Bioorganic & medicinal chemistry 20090915

• The crystal structure of an algal prolyl 4-hydroxylase complexed with a proline-rich peptide reveals a novel buried tripeptide binding motif.

  The Journal of biological chemistry 20090911

• Resolving the CSN and CAND1 paradoxes.

  Molecular cell 20090911

• F-box-directed CRL complex assembly and regulation by the CSN and CAND1.

  Molecular cell 20090911

• Mutation of a phosphorylatable residue in Put3p affects the magnitude of rapamycin-induced PUT1 activation in a Gat1p-dependent manner.

  The Journal of biological chemistry 20090904

• Functional importance of bacteriophage phi29 DNA polymerase residue Tyr148 in primer-terminus stabilisation at the 3'-5' exonuclease active site.

  Journal of molecular biology 20090904

• Trans-cis switching mechanisms in proline analogues and their relevance for the gating of the 5-HT3 receptor.

  The journal of physical chemistry. B 20090903

• Experimental and computational study on the molecular energetics of 2-pyrrolecarboxylic acid and 1-methyl-2-pyrrolecarboxylic acid.

  The journal of physical chemistry. A 20090903

• Effects of selenium on wheat seedlings under drought stress.

  Biological trace element research 20090901

• Ab initio studies of receptor interactions with AMPA ((S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl) propionic acid) and kainic acid (2S-(2 alpha, 3 beta, 4 beta))-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid.

  Journal of molecular modeling 20090901

• Study of the interactions between a proline-rich protein and a flavan-3-ol by NMR: residual structures in the natively unfolded protein provides anchorage points for the ligands.

  Biopolymers 20090901

• An apoA-I mimetic peptide containing a proline residue has greater in vivo HDL binding and anti-inflammatory ability than the 4F peptide.

  Journal of lipid research 20090901

• Salt stress affects glutamine synthetase activity and mRNA accumulation on potato plants in an organ-dependent manner.

  Plant physiology and biochemistry : PPB 20090901

• Influence of N-terminal domain histidine and proline residues on the substrate selectivities of human UDP-glucuronosyltransferase 1A1, 1A6, 1A9, 2B7, and 2B10.

  Drug metabolism and disposition: the biological fate of chemicals 20090901

• Toxicity and removal of heavy metals (cadmium, copper, and zinc) by Lemna gibba.

  Ecotoxicology and environmental safety 20090901

• In vivo activity of anprocide alone, and in vitro activity in combination with conventional antibiotics against Staphylococcus aureus and Staphylococcus epidermidis biofilms.

  Journal of medical microbiology 20090901

• Proteome analysis of tobacco leaves under salt stress.

  Peptides 20090901

• Stereoelectronic effects on the transition barrier of polyproline conformational interconversion.

  Protein science : a publication of the Protein Society 20090901

• The proline biosynthetic genes P5CS1 and P5CS2 play overlapping roles in Arabidopsis flower transition but not in embryo development.

  Physiologia plantarum 20090901

• NF-kappab facilitates oridonin-induced apoptosis and autophagy in HT1080 cells through a p53-mediated pathway.

  Archives of biochemistry and biophysics 20090901

• Effect of moderate salinity stress treatment on the stimulation of proline uptake and growth in Escherichia coli CSH4 and its mutants under high salinity.

  Journal of bioscience and bioengineering 20090901

• Synthesis and biological applications of imidazolium-based polymerized ionic liquid as a gene delivery vector.

  Chemical biology & drug design 20090901

• GAP-134 ([2S,4R]-1-[2-aminoacetyl]4-benzamidopyrrolidine-2-carboxylic acid) prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs.

  Journal of cardiovascular pharmacology and therapeutics 20090901

• The OsDHODH1 gene is involved in salt and drought tolerance in rice.

  Journal of integrative plant biology 20090901

• Exogenous proline and glycinebetaine suppress apoplastic flow to reduce Na(+) uptake in rice seedlings.

  Bioscience, biotechnology, and biochemistry 20090901

• Proline as a stress protectant in the yeast Saccharomyces cerevisiae: effects of trehalose and PRO1 gene expression on stress tolerance.

  Bioscience, biotechnology, and biochemistry 20090901

• Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation.

  Archives of general psychiatry 20090901

• Isolation and structural elucidation of euryjanicins B-D, proline-containing cycloheptapeptides from the Caribbean marine sponge Prosuberites laughlini.

  Journal of natural products 20090901

• Mmp-20 and Klk4 cleavage site preferences for amelogenin sequences.

  Journal of dental research 20090901

• Antineoplastic effects of nutrient mixture on raji and jurkat t cells: the two highly aggressive non Hodgkin's lymphoma cell lines.

  Experimental oncology 20090901

• A proline-based neuraminidase inhibitor: DFT studies on the zwitterion conformation, stability and formation.

  International journal of molecular sciences 20090901

• PBOND: web server for the prediction of proline and non-proline cis/trans isomerization.

  Genomics, proteomics & bioinformatics 20090901

• The effect of organ-specific CD26/DPP IV enzymatic activity inhibitor-preconditioning on acute pulmonary allograft rejection.

  Transplantation 20090827

• Central l-proline attenuates stress-induced dopamine and serotonin metabolism in the chick forebrain.

  Neuroscience letters 20090821

• Loss of function of a proline-containing protein confers durable disease resistance in rice.

  Science (New York, N.Y.) 20090821

• Switchable performance of an L-proline-derived basic catalyst controlled by supramolecular gelation.

  Journal of the American Chemical Society 20090819

• A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia.

  Proceedings of the National Academy of Sciences of the United States of America 20090818

• An investigation of the influence of chain length on the interfacial ordering of L-lysine and L-proline and their homopeptides at hydrophobic and hydrophilic interfaces studied by sum frequency generation and quartz crystal microbalance.

  Langmuir : the ACS journal of surfaces and colloids 20090818

• Discovery of a class of potent gap-junction modifiers as novel antiarrhythmic agents.

  Bioorganic & medicinal chemistry letters 20090815

• Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS.

  The Journal of biological chemistry 20090814

• Dependence of the AmII'p proline Raman band on peptide conformation.

  The journal of physical chemistry. B 20090813

• Chirality transfer effects in proline-substituted coumarin compounds.

  The journal of physical chemistry. B 20090813

• Is the backbone conformation of C(alpha)-methyl proline restricted to a single region?

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090810

• Structural effects on the catalytic, emulsifying, and recycling properties of chiral amphiphilic dendritic organocatalysts.

  The Journal of organic chemistry 20090807

• A novel iron-catalyzed decarboxylative Csp3-Csp2 coupling of proline derivatives and naphthol.

  Organic letters 20090806

• Transcriptome pathways unique to dehydration tolerant relatives of modern wheat.

  Functional & integrative genomics 20090801

• Waterlogging tolerance of Welsh onion (Allium fistulosum L.) enhanced by exogenous spermidine and spermine.

  Plant physiology and biochemistry : PPB 20090801

• GhDREB1 enhances abiotic stress tolerance, delays GA-mediated development and represses cytokinin signalling in transgenic Arabidopsis.

  Plant, cell & environment 20090801

• Cytosolic Aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1.

  Molecular pharmacology 20090801

• Isomerization of the proline in the M2-M3 linker is not required for activation of the human 5-HT3A receptor.

  Journal of neurochemistry 20090801

• Metastable atom-activated dissociation mass spectrometry: leucine/isoleucine differentiation and ring cleavage of proline residues.

  Journal of mass spectrometry : JMS 20090801

• Trehalose inhibits inflammatory cytokine production by protecting IkappaB-alpha reduction in mouse peritoneal macrophages.

  Archives of oral biology 20090801

• Increased expression of OsSPX1 enhances cold/subfreezing tolerance in tobacco and Arabidopsis thaliana.

  Plant biotechnology journal 20090801

• The Pro/Pro genotype of the p53 codon 72 polymorphism modulates PAI-1 plasma levels in ageing.

  Mechanisms of ageing and development 20090801

• Amino acids in the rat intestinal lumen regulate their own absorption from a distant intestinal site.

  American journal of physiology. Gastrointestinal and liver physiology 20090801

• Synthesis and evaluation of new endomorphin analogues modified at the Pro(2) residue.

  Bioorganic & medicinal chemistry letters 20090801

• Boceprevir, an NS3 protease inhibitor of HCV.

  Clinics in liver disease 20090801

• Sodium translocation by the iminoglycinuria associated imino transporter (SLC6A20).

  Molecular membrane biology 20090801

• Increased expression and activity of MMP-9 in C-reactive protein- induced human THP-1 mononuclear cells is related to activation of nuclear factor kappa-B.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090801

• Bilirubin effect on endothelial adhesion molecules expression is mediated by the NF-kappaB signaling pathway.

  Bioscience trends 20090801

• Effects of epitope sequence tandem repeat and proline incorporation on polyclonal antibody production against cytochrome 1A2 and 3A4.

  BMB reports 20090731

• Probing conformers and adsorption footprints at the single-molecule level in a highly organized amino acid assembly of (S)-proline on Cu(110).

  Journal of the American Chemical Society 20090729

• GAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through the activation of extracellular signal-regulated kinase signaling.

  The Journal of biological chemistry 20090724

• Network of hydrogen bonds in Pro-Ala-Pro and Pro-Phe-Pro diamides: a first principles study of Ala-->Phe point mutation in proline environment.

  The Journal of chemical physics 20090721

• Constrained beta-proline analogues in organocatalytic aldol reactions: the influence of acid geometry.

  The Journal of organic chemistry 20090717

• Synthesis of acrylic polymer beads for solid-supported proline-derived organocatalysts.

  Organic letters 20090716

• An enantioselective synthesis of (+)-(S)-[n]-gingerols via the L-proline-catalyzed aldol reaction.

  Bioorganic & medicinal chemistry letters 20090715

• Kinetic and mechanistic studies of proline-mediated direct intermolecular aldol reactions.

  Bioorganic & medicinal chemistry letters 20090715

• Origin of the stability conferred upon collagen by fluorination.

  Bioorganic & medicinal chemistry letters 20090715

• Preparation of L-proline based aeruginosin 298-A analogs: optimization of the P1-moiety.

  Bioorganic & medicinal chemistry letters 20090715

• Toll-like receptor 9 agonists promote IL-8 and TGF-beta1 production via activation of nuclear factor kappaB in PC-3 cells.

  Cancer genetics and cytogenetics 20090715

• TP53 mutations and Arg72Pro polymorphism in breast cancers.

  Cancer genetics and cytogenetics 20090715

• Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.

  Structure (London, England : 1993) 20090715

• Axonal release of glutamate analog, d-2,3-3H-Aspartic acid and l-14C-proline from segments of sciatic nerve following electrical and magnetic stimulation.

  Neuroscience letters 20090710

• Mutation in pyrroline-5-carboxylate reductase 1 gene in families with cutis laxa type 2.

  American journal of human genetics 20090710

• Stereoselective synthesis and biological evaluations of novel 3'-deoxy-4'-azaribonucleosides as inhibitors of hepatitis C virus RNA replication.

  Journal of medicinal chemistry 20090709

• Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL.

  Science signaling 20090707

• Highly enantio- and diastereoselective organocatalytic desymmetrization of prochiral cyclohexanones by simple direct aldol reaction catalyzed by proline.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090706

• L-proline is a sedative regulator of acute stress in the brain of neonatal chicks.

  Amino acids 20090701

• Nickel-induced changes in nitrogen metabolism in wheat shoots.

  Journal of plant physiology 20090701

• Synthesis, characterisation and in vitro cytotoxicity studies of a series of chiral platinum(II) complexes based on the 2-aminomethylpyrrolidine ligand: X-ray crystal structure of [PtCl2(R-dimepyrr)] (R-dimepyrr=N-dimethyl-2(R)-aminomethylpyrrolidine).

  European journal of medicinal chemistry 20090701

• Amino acid-mediated heterotypic interaction governs performance of a hepatic tissue model.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090701

• N-(pyrrole-2-carboxyl) glycine a diagnostic marker of hyperprolinaemia type II: mass spectra of trimethylsilyl derivatives.

  Clinica chimica acta; international journal of clinical chemistry 20090701

• Regulation of the formation and trafficking of vesicles from Golgi by PCH family proteins during chemotaxis.

  Biochimica et biophysica acta 20090701

• Regulation and function of proline oxidase under nutrient stress.

  Journal of cellular biochemistry 20090701

• Multicomponent analyses of chiral samples by use of regression analysis of UV-visible spectra of cyclodextrin guest-host complexes.

  Analytical and bioanalytical chemistry 20090701

• NAD(P)H:quinone oxidoreductase 1 Pro187Ser polymorphism and expression do not cosegregate with clinico-pathological characteristics of human mammary tumors.

  Pharmacogenetics and genomics 20090701

• Doubly tethered tertiary amide linked and ionically bonded diproline chiral stationary phases.

  Journal of separation science 20090701

• Mutational analysis of uncharged polar residues and proline in the distal one-third (Thr130-Pro142) of the highly conserved region of mouse Slc10a2.

  Bioscience, biotechnology, and biochemistry 20090701

• Pro12Ala polymorphism in PPARgamma2 associated with depression in Chinese nonagenarians/centenarians.

  Archives of medical research 20090701

• Biochemical characterization of the prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B complex.

  The Journal of biological chemistry 20090626

• Toward the back-up of boceprevir (SCH 503034): discovery of new extended P4-capped ketoamide inhibitors of hepatitis C virus NS3 serine protease with improved potency and pharmacokinetic profiles.

  Journal of medicinal chemistry 20090625

• Substitution of arginine with proline and proline derivatives in melanocyte-stimulating hormones leads to selectivity for human melanocortin 4 receptor.

  Journal of medicinal chemistry 20090625

• 3S-fluoroproline as a probe to monitor proline isomerization during protein folding by 19F-NMR.

  Chemical communications (Cambridge, England) 20090621

• Asymmetric synthesis of 2-azabicyclo[3.3.1]nonanes by a microwave-assisted organocatalysed tandem desymmetrisation and intramolecular aldolisation.

  Organic & biomolecular chemistry 20090621

• Evaluation of triproline and tri-alpha-methylproline chiral stationary phases: retention and enantioseparation associated with hydrogen bonding.

  Journal of chromatography. A 20090619

• Iterative approach to enantiopure syn/anti-1,3-polyols via proline-catalyzed sequential alpha-aminoxylation and Horner-Wadsworth-Emmons olefination of aldehydes.

  Organic letters 20090618

• Potent activity of a PK/PBAN analog with an (E)-alkene, trans-Pro mimic identifies the Pro orientation and core conformation during interaction with HevPBANR-C receptor.

  Bioorganic & medicinal chemistry 20090615

• Direct aldol reactions catalyzed by intramolecularly folded prolinamide dendrons: dendrimer effects on stereoselectivity.

  Chemical communications (Cambridge, England) 20090614

• An unfolded CH1 domain controls the assembly and secretion of IgG antibodies.

  Molecular cell 20090612

• Evidence that biosynthesis of the neurotoxic alkaloids anatoxin-a and homoanatoxin-a in the cyanobacterium Oscillatoria PCC 6506 occurs on a modular polyketide synthase initiated by L-proline.

  Journal of the American Chemical Society 20090610

• Observation of two new conformers of neutral proline.

  Physical chemistry chemical physics : PCCP 20090607

• Conformational dynamics of the inner pore helix of voltage-gated potassium channels.

  The Journal of chemical physics 20090607

• Synthesis of proline-based diketopiperazine scaffolds.

  The Journal of organic chemistry 20090605

• Organocatalytic syn-aldol reactions of dioxanones with (S)-isoserinal hydrate: synthesis of L-deoxymannojirimycin and L-deoxyidonojirimycin.

  The Journal of organic chemistry 20090605

• Synthesis of alpha-cyclopropyl-beta-homoprolines.

  The Journal of organic chemistry 20090605

• In silico molecular engineering for a targeted replacement in a tumor-homing peptide.

  The journal of physical chemistry. B 20090604

• Lincomycin, rational selection of high producing strain and improved fermentation by amino acids supplementation.

  Bioprocess and biosystems engineering 20090601

• PDTC enables type I TRAIL signaling in type II follicular lymphoma cells.

  Leukemia research 20090601

• Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway.

  Lung cancer (Amsterdam, Netherlands) 20090601

• Puckering transitions of pseudoproline residues.

  Biopolymers 20090601

• Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension.

  Cardiovascular research 20090601

• The gap junction modifier, GAP-134 [(2S,4R)-1-(2-aminoacetyl)-4-benzamido-pyrrolidine-2-carboxylic acid], improves conduction and reduces atrial fibrillation/flutter in the canine sterile pericarditis model.

  The Journal of pharmacology and experimental therapeutics 20090601

• Synthesis of a proline-modified acrylic acid copolymer in supercritical CO2 for glass-ionomer dental cement applications.

  Acta biomaterialia 20090601

• The neurofilament light chain gene (NEFL) mutation Pro22Ser can be associated with mixed axonal and demyelinating neuropathy.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20090601

• Methyl group migration during the fragmentation of singly charged ions of trimethyllysine-containing peptides: precaution of using MS/MS of singly charged ions for interrogating peptide methylation.

  Journal of the American Society for Mass Spectrometry 20090601

• Expression of an elicitor-encoding gene from Magnaporthe grisea enhances resistance against blast disease in transgenic rice.

  Plant cell reports 20090601

• Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats.

  Brain research 20090601

• Association of the growth hormone receptor gene polymorphisms with mandibular height in a Korean population.

  Archives of oral biology 20090601

• Total chemical synthesis of the D2 domain of human VEGF receptor 1.

  Journal of peptide science : an official publication of the European Peptide Society 20090601

• Biological activity of endomorphin and [Dmt1]endomorphin analogs with six-membered proline surrogates in position 2.

  Bioorganic & medicinal chemistry 20090601

• Comparative effects of fatty acids on proinflammatory gene cyclooxygenase 2 and inducible nitric oxide synthase expression in retinal pigment epithelial cells.

  Molecular nutrition & food research 20090601

• Mitochondrial and axonal abnormalities precede disruption of the neurofilament network in a model of charcot-marie-tooth disease type 2E and are prevented by heat shock proteins in a mutant-specific fashion.

  Journal of neuropathology and experimental neurology 20090601

• Thermally denatured state determines refolding in lipase: mutational analysis.

  Protein science : a publication of the Protein Society 20090601

• The effects of PDTC on interleukin-1beta-induced nitric oxide production in chondrocytes.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090601

• Sequence-specific 1H, 15N and 13C resonance assignments of Art v 1: a proline-rich allergen of Artemisia vulgaris pollen.

  Biomolecular NMR assignments 20090601

• Physiological and genetic properties of tomato fruits from 2 cultivars differing in chilling tolerance at cold storage.

  Journal of food science 20090601

• Antinociceptive synergistic effect of spinal mGluR2/3 antagonist and glial cells inhibitor on peripheral inflammation-induced mechanical hypersensitivity.

  Brain research bulletin 20090529

• Stress-tolerance of baker's-yeast (Saccharomyces cerevisiae) cells: stress-protective molecules and genes involved in stress tolerance.

  Biotechnology and applied biochemistry 20090529

• The mechanism of domain alternation in the acyl-adenylate forming ligase superfamily member 4-chlorobenzoate: coenzyme A ligase.

  Biochemistry 20090519

• SH3 domains of Grb2 adaptor bind to PXpsiPXR motifs within the Sos1 nucleotide exchange factor in a discriminate manner.

  Biochemistry 20090519

• Yeast heat-shock protein gene HSP26 enhances freezing tolerance in Arabidopsis.

  Journal of plant physiology 20090515

• Dominant roles of the polybasic proline motif and copper in the PrP23-89-mediated stress protection response.

  Journal of cell science 20090515

• Precision gels from collagen-inspired triblock copolymers.

  Biomacromolecules 20090511

• Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S.

  The Journal of biological chemistry 20090508

• Model of human butyrylcholinesterase tetramer by homology modeling and dynamics simulation.

  The journal of physical chemistry. B 20090507

• Density functional theory study of the binding of glycine, proline, and hydroxyproline to the hydroxyapatite (0001) and (0110) surfaces.

  Langmuir : the ACS journal of surfaces and colloids 20090505

• Importance of hydrogen-bonding sites in the chiral recognition mechanism between racemic D3 terbium(III) complexes and amino acids.

  Chirality 20090501

• Relationship between proline and Hg2+-induced oxidative stress in a tolerant rice mutant.

  Archives of environmental contamination and toxicology 20090501

• An all-atom structure-based potential for proteins: bridging minimal models with all-atom empirical forcefields.

  Proteins 20090501

• Conformational preferences of N-methoxycarbonyl proline dipeptide.

  Journal of computational chemistry 20090501

• Role of antioxidants in Cr tolerance of three crop plants: Metal accumulation in seeds.

  Ecotoxicology and environmental safety 20090501

• Transrectal natural orifice transluminal endoscopic surgery for umbilical hernia repair in a human cadaver (with video).

  Gastrointestinal endoscopy 20090501

• Proline 146 is critical to the structure, function and targeting of sod2, the Na+/H+ exchanger of Schizosaccharomyces pombe.

  Biochimica et biophysica acta 20090501

• Glycine- and proline-rich glycoprotein regulates the balance between cell proliferation and apoptosis for ACF formation in 1,2-dimethylhydrazine-treated A/J mice.

  Molecular and cellular biochemistry 20090501

• PPAR gamma variant influences angiographic outcome and 10-year cardiovascular risk in male symptomatic coronary artery disease patients.

  Diabetes care 20090501

• Kinetic folding studies of the P22 tailspike beta-helix domain reveal multiple unfolded states.

  Biophysical chemistry 20090501

• The contribution of proline residues to protein stability is associated with isomerization equilibrium in both unfolded and folded states.

  Extremophiles : life under extreme conditions 20090501

• Using Caveolin-1 epithelial immunostaining patterns to stratify human breast cancer patients and predict the Caveolin-1 (P132L) mutation.

  Cell cycle (Georgetown, Tex.) 20090501

• An indel in transmembrane helix 2 helps to trace the molecular evolution of class A G-protein-coupled receptors.

  Journal of molecular evolution 20090501

• Identification of anti-asthmatic compounds in Pericarpium citri reticulatae and evaluation of their synergistic effects.

  Acta pharmacologica Sinica 20090501

• p53 Arg72Pro and MDM2 T309G polymorphisms, histology, and esophageal cancer prognosis.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090501

• Effect and mechanism of intense pulsed laser on skin aging in rats.

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20090501

• Increased association between rough endoplasmic reticulum membranes and mitochondria in transgenic mice that express P301L tau.

  Journal of neuropathology and experimental neurology 20090501

• Association between sigma-1 receptor gene polymorphism and prefrontal hemodynamic response induced by cognitive activation in schizophrenia.

  Progress in neuro-psychopharmacology & biological psychiatry 20090430

• NMR study of the cataract-linked P23T mutant of human gammaD-crystallin shows minor changes in hydrophobic patches that reflect its retrograde solubility.

  Biochemical and biophysical research communications 20090424

• Free amino acids as phagostimulants in cricket nuptial gifts: support for the 'Candymaker' hypothesis.

  Biology letters 20090423

• Synthesis of cyclic peptide analogues of the 3(10) helical Pro138-Gly144 segment of human aquaporin-4 by olefin metathesis.

  Organic & biomolecular chemistry 20090421

• The role of non-synonymous NPY gene polymorphism in the nitric oxide production in HUVECs.

  Biochemical and biophysical research communications 20090417

• An enantioselective organocatalytic approach to both enantiomers of lasubine II.

  The Journal of organic chemistry 20090417

• Protonation of the side group in beta- and gamma-aminated proline analogues: effects on the conformational preferences.

  The Journal of organic chemistry 20090417

• Shuttling gold nanoparticles into tumoral cells with an amphipathic proline-rich peptide.

  Chembiochem : a European journal of chemical biology 20090417

• Effect of a carboxyl group on the chemiluminescent reaction of tris(2,2'-bipyridine)ruthenium(III) with aliphatic amines.

  Talanta 20090415

• Properties of the thioredoxin fold superfamily are modulated by a single amino acid residue.

  The Journal of biological chemistry 20090410

• Palmitoylation controls the catalytic activity and subcellular distribution of phosphatidylinositol 4-kinase II{alpha}.

  The Journal of biological chemistry 20090410

• Structural basis of glyphosate resistance resulting from the double mutation Thr97 -> Ile and Pro101 -> Ser in 5-enolpyruvylshikimate-3-phosphate synthase from Escherichia coli.

  The Journal of biological chemistry 20090410

• Molecular determinants of a native-state prolyl isomerization.

  Journal of molecular biology 20090410

• Abundant dipositively charged protonated a2 and a3 ions from diproline and triproline.

  The journal of physical chemistry. B 20090409

• Novel de novo SHANK3 mutation in autistic patients.

  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20090405

• Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives.

  The Journal of biological chemistry 20090403

• Erythrocytosis-associated HIF-2alpha mutations demonstrate a critical role for residues C-terminal to the hydroxylacceptor proline.

  The Journal of biological chemistry 20090403

• Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain.

  Journal of molecular biology 20090403

• Essential role of Pro 74 in stefin B amyloid-fibril formation: dual action of cyclophilin A on the process.

  FEBS letters 20090402

• Asymmetric aldol reactions catalyzed by efficient and recyclable silica-supported proline-based peptides.

  Chirality 20090401

• Effect of administration of oral contraceptives in vivo on collagen synthesis in tendon and muscle connective tissue in young women.

  Journal of applied physiology (Bethesda, Md. : 1985) 20090401

• Effect of estrogen on tendon collagen synthesis, tendon structural characteristics, and biomechanical properties in postmenopausal women.

  Journal of applied physiology (Bethesda, Md. : 1985) 20090401

• Effects of repeated exposure to cocaine on group II metabotropic glutamate receptor function in the rat medial prefrontal cortex: behavioral and neurochemical studies.

  Psychopharmacology 20090401

• Straightforward and de novo peptide sequencing by MALDI-MS/MS using a Lys-N metalloendopeptidase.

  Molecular & cellular proteomics : MCP 20090401

• Crystal structures and spectroscopic properties of ester amide and diamide of squaric acid with prolinamide.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090401

• Ectopic overexpression of AtHDG11 in tall fescue resulted in enhanced tolerance to drought and salt stress.

  Plant cell reports 20090401

• Putrescine overproduction negatively impacts the oxidative state of poplar cells in culture.

  Plant physiology and biochemistry : PPB 20090401

• Crystal structure of human osteoclast stimulating factor.

  Proteins 20090401

• Effect of proline on thermal inactivation, denaturation and aggregation of glycogen phosphorylase b from rabbit skeletal muscle.

  Biophysical chemistry 20090401

• Topology of mammalian isoprenylcysteine carboxyl methyltransferase determined in live cells with a fluorescent probe.

  Molecular and cellular biology 20090401

• Cellular and functional analysis of four mutations located in the mitochondrial ATPase6 gene.

  Journal of cellular biochemistry 20090401

• An efficient ultrasound-promoted synthesis of the Baylis-Hillman adducts catalyzed by imidazole and L-proline.

  Ultrasonics sonochemistry 20090401

• Breast-feeding modifies the association of PPARgamma2 polymorphism Pro12Ala with growth in early life: the Generation R Study.

  Diabetes 20090401

• Stability over 36 months of a new liquid 10% polyclonal immunoglobulin product (IgPro10, Privigen) stabilized with L-proline.

  Vox sanguinis 20090401

• Intra- and intermolecular interaction inducing pyramidalization on both sides of a proline dipeptide during isomerization: an ab initio QM/MM molecular dynamics simulation study in explicit water.

  Journal of the American Chemical Society 20090401

• Probing of the cis-5-phenyl proline scaffold as a platform for the synthesis of mechanism-based inhibitors of the Staphylococcus aureus sortase SrtA isoform.

  Bioorganic & medicinal chemistry 20090401

• The presence of a matrix-derived neutrophil chemoattractant in bronchiolitis obliterans syndrome after lung transplantation.

  Journal of immunology (Baltimore, Md. : 1950) 20090401

• The Pro12Ala polymorphism of the PPARgamma2 gene is associated with hepatic glucose uptake during hyperinsulinemia in subjects with type 2 diabetes mellitus.

  Metabolism: clinical and experimental 20090401

• Work of flexion related to different suture materials after flexor digitorum profundus and flexor digitorum superficialis tendon repair in zone II: a biomechanical study.

  The Journal of hand surgery 20090401

• [Novel treatment for chronic hepatitis C in near future].

  Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20090401

• Early Tau pathology involving the septo-hippocampal pathway in a Tau transgenic model: relevance to Alzheimer's disease.

  Current Alzheimer research 20090401

• Amyloidogenesis abolished by proline substitutions but enhanced by lipid binding.

  PLoS computational biology 20090401

• The interaction of proline-rich ligands with profilin probed with an enzyme-linked immunosorbent assay.

  Journal of biomolecular screening 20090401

• Effects of chronic gap junction conduction-enhancing antiarrhythmic peptide GAP-134 administration on experimental atrial fibrillation in dogs.

  Circulation. Arrhythmia and electrophysiology 20090401

• Design and synthesis of glucose-templated proline-lysine chimera: polyfunctional amino acid chimera with high prolyl cis amide rotamer population.

  Carbohydrate research 20090331

• A thorough study on the use of quantitative 1H NMR in Rioja red wine fermentation processes.

  Journal of agricultural and food chemistry 20090325

• Assembly of substituted 3-methyleneisoindolin-1-ones via a CuI/l-proline-catalyzed domino reaction process of 2-bromobenzamides and terminal alkynes.

  Organic letters 20090319

• Dual palladium- and proline-catalyzed allylic alkylation of enolizable ketones and aldehydes with allylic alcohols.

  Organic letters 20090319

• Physiological responses among Brassica species under salinity stress show strong correlation with transcript abundance for SOS pathway-related genes.

  Journal of plant physiology 20090315

• A single conserved proline residue determines the membrane topology of stomatin.

  The Biochemical journal 20090315

• Direct and continuous assay for prolyl 4-hydroxylase.

  Analytical biochemistry 20090315

• A generic mechanism of beta2-microglobulin amyloid assembly at neutral pH involving a specific proline switch.

  Journal of molecular biology 20090313

• Mechanical design of the third FnIII domain of tenascin-C.

  Journal of molecular biology 20090313

• The proline-rich N-terminal sequence of calcineurin Abeta determines substrate binding.

  Biochemistry 20090310

• Direct enantioselective aldol reactions catalyzed by a proline-thiourea host-guest complex.

  Chemical communications (Cambridge, England) 20090307

• Enantioselective Mannich reactions with the practical proline mimetic N-(p-dodecylphenyl-sulfonyl)-2-pyrrolidinecarboxamide.

  The Journal of organic chemistry 20090306

• Phytic acid increases mucin and endogenous amino acid losses from the gastrointestinal tract of chickens.

  The British journal of nutrition 20090301

• Fluorescence study on site-specific binding of perfluoroalkyl acids to human serum albumin.

  Archives of toxicology 20090301

• Can N-methylated amino acids serve as substitutes for prolines in conformational design of cyclic pentapeptides?

  Journal of peptide science : an official publication of the European Peptide Society 20090301

• Physiological responses of somaclonal variants of triploid bermudagrass (Cynodon transvaalensis x Cynodon dactylon) to drought stress.

  Plant cell reports 20090301

• Effect of proline substitutions on stability and kinetic properties of a cold adapted subtilase.

  Journal of biochemistry 20090301

• C-terminal tail derived from the neighboring subunit is critical for the activity of Thermoplasma acidophilum D-aldohexose dehydrogenase.

  Proteins 20090301

• Effects of salt stress on the expression of antioxidant genes and proteins in the model legume Lotus japonicus.

  The New phytologist 20090301

• HPLC-fluorescence detection method for determination of key intermediates of the lincomycin biosynthesis in fermentation broth.

  Analytical and bioanalytical chemistry 20090301

• Role of the N-terminal alpha-helix in biogenesis of alpha7 nicotinic receptors.

  Journal of neurochemistry 20090301

• SOAR and the polybasic STIM1 domains gate and regulate Orai channels.

  Nature cell biology 20090301

• A computational approach to correct arginine-to-proline conversion in quantitative proteomics.

  Nature methods 20090301

• Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein.

  The European journal of neuroscience 20090301

• Cadmium: toxicity and tolerance in plants.

  Journal of environmental biology 20090301

• Cadmium induced changes on proline, antioxidant enzymes, nitrate and nitrite reductases in Arachis hypogaea L.

  Journal of environmental biology 20090301

• Proline accumulation in lemongrass (Cymbopogon flexuosus Stapf.) due to heavy metal stress.

  Journal of environmental biology 20090301

• Mutation effects on structural stability of polyglutamine peptides by molecular dynamics simulation.

  Interdisciplinary sciences, computational life sciences 20090301

• Discovery of (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride (GAP-134)13, an orally active small molecule gap-junction modifier for the treatment of atrial fibrillation.

  Journal of medicinal chemistry 20090226

• Characterization of novel 2-oxoglutarate dependent dioxygenases converting L-proline to cis-4-hydroxy-l-proline.

  Biochemical and biophysical research communications 20090220

• A highly regioselective ring-opening metathesis-cross metathesis process modulated by the electronic effects of the cross metathesis partner: an entry to quaternary prolines.

  The Journal of organic chemistry 20090220

• Use of bifunctional ureas to increase the rate of proline-catalyzed alpha-aminoxylations.

  The Journal of organic chemistry 20090220

• Asymmetric Lewis acid mediated [1,2]-rearrangement of proline-derived ammonium ylides.

  Organic letters 20090219

• Simultaneous measurement of proline and related compounds in oak leaves by high-performance ligand-exchange chromatography and electrospray ionization mass spectrometry for environmental stress studies.

  Journal of chromatography. A 20090213

• Rate limiting step precedes C-C bond formation in the archetypical proline-catalyzed intramolecular aldol reaction.

  Journal of the American Chemical Society 20090211

• A conserved active site tyrosine residue of proline dehydrogenase helps enforce the preference for proline over hydroxyproline as the substrate.

  Biochemistry 20090210

• Proline-directed phosphorylation of the dopamine transporter N-terminal domain.

  Biochemistry 20090210

• Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growth.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090204

• Diphenylprolinol silyl ether as a catalyst in an enantioselective, catalytic michael reaction for the formation of alpha,alpha-disubstituted alpha-amino acid derivatives.

  Chemistry, an Asian journal 20090202

• Effects of supplemental ultraviolet-B and cadmium on growth, antioxidants and yield of Pisum sativum L.

  Ecotoxicology and environmental safety 20090201

• Prediction of cis/trans isomerization using feature selection and support vector machines.

  Journal of biomedical informatics 20090201

• Proline affects brain function in 22q11DS children with the low activity COMT 158 allele.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090201

• Ultrasound-promoted synthesis of novel dispirocyclic frameworks from aza-Claisen rearrangements of Baylis-Hillman amines.

  Ultrasonics sonochemistry 20090201

• A role for the p53 pathway in the pathology of meningiomas with NF2 loss.

  Journal of neuro-oncology 20090201

• Mast cells reduce survival of myenteric neurons in culture.

  Neuropharmacology 20090201

• Protective effects of proline against cadmium toxicity in micropropagated hyperaccumulator, Solanum nigrum L.

  Plant cell reports 20090201

• The helical content of the YscP molecular ruler determines the length of the Yersinia injectisome.

  Molecular microbiology 20090201

• Two non-redundant fragments in the N-terminal peptide of human cytosolic methionyl-tRNA synthetase were indispensable for the multi-synthetase complex incorporation and enzyme activity.

  Biochimica et biophysica acta 20090201

• Striking phenotypic variability in two familial cases of myosin storage myopathy with a MYH7 Leu1793pro mutation.

  Neuromuscular disorders : NMD 20090201

• Simple and rapid genotyping of D-amino acid oxidase gene recognizing a crucial variant in the ddY strain using microchip electrophoresis.

  Journal of separation science 20090201

• Treatment of chronic hepatitis C: anticipated impact of resistance in patients treated with protease inhibitors.

  Current gastroenterology reports 20090201

• Synthesis, cytotoxic and antimicrobial screening of a proline-rich cyclopolypeptide.

  Chemical & pharmaceutical bulletin 20090201

• Helix 3 is necessary and sufficient for prion protein's anti-Bax function.

  Journal of neurochemistry 20090201

• Boceprevir, an NS3 serine protease inhibitor of hepatitis C virus, for the treatment of HCV infection.

  Current opinion in investigational drugs (London, England : 2000) 20090201

• Expression of jasmonic ethylene responsive factor gene in transgenic poplar tree leads to increased salt tolerance.

  Tree physiology 20090201

• Capillary electrophoresis with electrochemiluminescence detection for simultaneous determination of proline and fleroxacin in human urine.

  Drug testing and analysis 20090201

• Proline accumulation and transcriptional regulation of proline biosynthesis and degradation in Brassica napus.

  BMB reports 20090131

• Proline and glycinebetaine induce antioxidant defense gene expression and suppress cell death in cultured tobacco cells under salt stress.

  Journal of plant physiology 20090130

• The intracellular mobility of NPY and a putative mitochondrial form of NPY in neuronal cells.

  Neuroscience letters 20090130

• A new amyloid-like beta-aggregate with amyloid characteristics, except fibril morphology.

  Journal of molecular biology 20090130

• Crystal structure of human adenylate kinase 4 (L171P) suggests the role of hinge region in protein domain motion.

  Biochemical and biophysical research communications 20090130

• Fragment molecular orbital calculations on red fluorescent proteins (DsRed and mFruits).

  The journal of physical chemistry. B 20090129

• Protective effects of asiatic acid against D-galactosamine/lipopolysaccharide-induced hepatotoxicity in hepatocytes and kupffer cells co-cultured system via redox-regulated leukotriene C4 synthase expression pathway.

  European journal of pharmacology 20090128

• Evidence that thienamycin biosynthesis proceeds via C-5 epimerization: ThnE catalyzes the formation of (2S,5S)-trans-carboxymethylproline.

  Chembiochem : a European journal of chemical biology 20090126

• Identification of physiological and toxic conformations in Abeta42 aggregates.

  Chembiochem : a European journal of chemical biology 20090126

• Small-molecule inhibitors of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism.

  Proceedings of the National Academy of Sciences of the United States of America 20090120

• In vivo profiling of DPP4 inhibitors reveals alterations in collagen metabolism and accumulation of an amyloid peptide in rat plasma.

  Biochemical pharmacology 20090115

• Effect of salinity on organic solutes contents in barley.

  Pakistan journal of biological sciences : PJBS 20090115

• A Cav3.2 T-type calcium channel point mutation has splice-variant-specific effects on function and segregates with seizure expression in a polygenic rat model of absence epilepsy.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090114

• Group II metabotropic glutamate receptor activation on peripheral nociceptors modulates TRPV1 function.

  Brain research 20090112

• Supramolecular gel formation and self-correction induced by aggregation-driven conformational changes.

  Chemical communications (Cambridge, England) 20090108

• A proline-rich peptide improves cell transfection of solid lipid nanoparticle-based non-viral vectors.

  Journal of controlled release : official journal of the Controlled Release Society 20090105

• Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of multiple sclerosis.

  Neuroscience letters 20090102

• Parkinson's disease and the heterozygous state for glucocerebrosidase mutations among Brazilians.

  Parkinsonism & related disorders 20090101

• Effect of cysteine modification on creatine kinase aggregation.

  Applied biochemistry and biotechnology 20090101

• Synthesis and characterization of a novel fast-set proline-derivative-containing glass ionomer cement with enhanced mechanical properties.

  Acta biomaterialia 20090101

• Interaction between PPARG Pro12Ala and ADIPOQ G276T concerning cholesterol levels in childhood obesity.

  International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity 20090101

• Imaging of fibrogenesis in patients with idiopathic pulmonary fibrosis with cis-4-[(18)F]-Fluoro-L: -proline PET.

  Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20090101

• Effects on haemolytic activity of single proline substitutions in the Bordetella pertussis CyaA pore-forming fragment.

  Archives of microbiology 20090101

• Oxidative stress and DNA damage in broad bean (Vicia faba L.) seedlings induced by thallium.

  Environmental toxicology and chemistry 20090101

• Association of free amino acids with caries experience and mutans streptococci levels in whole saliva of children with early childhood caries.

  Archives of oral biology 20090101

• Interaction between the N-terminal SH3 domain of Nck-alpha and CD3-epsilon-derived peptides: non-canonical and canonical recognition motifs.

  Biochimica et biophysica acta 20090101

• Proline effect on the thermostability and slow unfolding of a hyperthermophilic protein.

  Journal of biochemistry 20090101

• Aging and alpha-synuclein affect synaptic plasticity in the dentate gyrus.

  Journal of neural transmission (Vienna, Austria : 1996) 20090101

• The evolution of pyrroline-5-carboxylate synthase in plants: a key enzyme in proline synthesis.

  Molecular genetics and genomics : MGG 20090101

• Association between Presenilin-1 and TRAF6 modulates regulated intramembrane proteolysis of the p75NTR neurotrophin receptor.

  Journal of neurochemistry 20090101

• Nicotianamine and histidine/proline are, respectively, the most important copper chelators in xylem sap of Brassica carinata under conditions of copper deficiency and excess.

  Journal of experimental botany 20090101

• Iodocyclization of chiral CF3-allylmorpholinones: a versatile strategy for the synthesis of enantiopure alpha-Tfm-prolines and alpha-Tfm-dihydroxyprolines.

  Organic letters 20090101

• Diphenylprolinol silyl ether catalysis in an asymmetric formal carbo [3 + 3] cycloaddition reaction via a domino Michael/Knoevenagel condensation.

  Organic letters 20090101

• Regulation of the trigeminal NR1 subunit expression induced by inflammation of the temporomandibular joint region in rats.

  Pain 20090101

• Novel chemotactic For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on met residue replacement by 4-amino-proline scaffold: synthesis and bioactivity.

  Bioorganic & medicinal chemistry 20090101

• High-yielding synthesis of the anti-influenza neuramidase inhibitor (-)-oseltamivir by three 'one-pot' operations.

  Angewandte Chemie (International ed. in English) 20090101

• Density functional study of proline-catalyzed intramolecular Baylis-Hillman reactions.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090101

• Cocaine induces cell death and activates the transcription nuclear factor kappa-B in PC12 cells.

  Molecular brain 20090101

• The proline-catalyzed double Mannich reaction of acetaldehyde with N-Boc imines.

  Angewandte Chemie (International ed. in English) 20090101

• Stabilization of neutral NH2-R-COOH form of the antihypertensive peptides L-Valyl-L-Prolyl-L-Proline and L-Isoleucyl-L-Prolyl-L-Proline.

  Protein and peptide letters 20090101

• Successful establishment of MEKC with electrochemiluminescence detection based on one functionalized ionic liquid.

  Electrophoresis 20090101

• Actions of a proline analogue, L-thiazolidine-4-carboxylic acid (T4C), on Trypanosoma cruzi.

  PloS one 20090101

• Stereochemical preference in the reactions of N-protected L-amino acid 1-hydroxybenzotriazole esters with racemic amino acid derivatives.

  Protein and peptide letters 20090101

• Increased proline loading to phloem and its effects on nitrogen uptake and assimilation in water-stressed white clover (Trifolium repens).

  The New phytologist 20090101

• 5-(Pyrrolidin-2-yl)tetrazole-catalyzed aldol and mannich reactions: acceleration and lower catalyst loading in a continuous-flow reactor.

  Angewandte Chemie (International ed. in English) 20090101

• Fluorous parallel synthesis of a piperazinedione-fused tricyclic compound library.

  Journal of combinatorial chemistry 20090101

• Direct catalytic asymmetric synthesis of highly functionalized 2-methylchroman-2,4-diols via Barbas-list aldol reaction.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090101

• Folding machineries displayed on a cation-exchanger for the concerted refolding of cysteine- or proline-rich proteins.

  BMC biotechnology 20090101

• A sequential o-nitrosoaldol and Grignard addition process: an enantio- and diastereoselective entry to chiral 1,2-diols.

  Angewandte Chemie (International ed. in English) 20090101

• The orally active antihyperglycemic drug beta-guanidinopropionic acid is transported by the human proton-coupled amino acid transporter hPAT1.

  Molecular pharmaceutics 20090101

• Conformational preferences and cis-trans isomerization of L-3,4-dehydroproline residue.

  Biopolymers 20090101

• Conformations of heterochiral and homochiral proline-pseudoproline segments in peptides: context dependent cis-trans peptide bond isomerization.

  Biopolymers 20090101

• Detection of discriminative sequence patterns in the neighborhood of proline cis peptide bonds and their functional annotation.

  BMC bioinformatics 20090101

• Introduction of N-alkyl residues in proline-rich peptides: effect on SH3 binding affinity and peptide conformation.

  Advances in experimental medicine and biology 20090101

• Synthesis and biological activity of novel alpha-conotoxin analogues incorporating substituted proline derivatives.

  Advances in experimental medicine and biology 20090101

• Fully automated fast Fmoc synthesis and on-resin disulfide bridge formation with pseudoproline dipeptides on the Prelude.

  Advances in experimental medicine and biology 20090101

• Proline-based diketopiperazine-scaffolds.

  Advances in experimental medicine and biology 20090101

• Modulating collagen triple-helix stability with 4-chloro, 4-fluoro, and 4-methylprolines.

  Advances in experimental medicine and biology 20090101

• Effect of 4-fluoro-L-proline on the SH3 binding affinity.

  Advances in experimental medicine and biology 20090101

• Analogues of arginine vasopressin modified at position 2 with proline derivatives: selective antagonists of oxytocin in vitro.

  Advances in experimental medicine and biology 20090101

• Effects of insoluble Zn, Cd, and EDTA on the growth, activities of antioxidant enzymes and uptake of Zn and Cd in Vetiveria zizanioides.

  Journal of environmental sciences (China) 20090101

• Mechanism of betulinic acid inhibition of collagen biosynthesis in human endometrial adenocarcinoma cells.

  Neoplasma 20090101

• Summer dormancy and winter growth: root survival strategy in a perennial monocotyledon.

  The New phytologist 20090101

• PPARgamma Pro12Ala polymorphism and risk of acute coronary syndrome in a prospective study of Danes.

  BMC medical genetics 20090101

• Founder heterozygous P23T CRYGD mutation associated with cerulean (and coralliform) cataract in 2 Saudi families.

  Molecular vision 20090101

• [Experimental pharmacokinetics of the new neurotensine-derived antipsychotic drug dilept].

  Eksperimental'naia i klinicheskaia farmakologiia 20090101

• Hb Nile[A1] and Hb Nile[A2]: novel identical [alpha77(EF6)Pro-->Ser] variants found in either the alpha1- or alpha2-globin genes.

  Hemoglobin 20090101

• A second case of Hb Fontainebleau [alpha21(B2)Ala-->Pro] in an individual with microcytosis.

  Hemoglobin 20090101

• Pachyonychia congenita type I presenting with subtle nail changes.

  Pediatric dermatology 20090101

• Highly enantioselective epoxidation of styrenes catalyzed by proline-derived C1-symmetric titanium(salan) complexes.

  Angewandte Chemie (International ed. in English) 20090101

• Organocatalytic, asymmetric aldol reactions with a sustainable catalyst in a green solvent.

  ChemSusChem 20090101

• The antibacterial effect of a proline-rich antibacterial peptide A3-APO.

  Current medicinal chemistry 20090101

• Rules governing selective protein carbonylation.

  PloS one 20090101

• Peptide bound hypohydroxyprolinuria in Handigodu Disease: a familial syndrome of spondylo epi(meta)physeal dysplasia.

  Disease markers 20090101

• p53 Amino-terminus region (1-125) stabilizes and restores heat denatured p53 wild phenotype.

  PloS one 20090101

• Chemopreventive effect of a novel nutrient mixture on lung tumorigenesis induced by urethane in male A/J mice.

  Tumori 20090101

• Anti-angiogenic actions of pyrrolidine dithiocarbamate, a nuclear factor kappa B inhibitor.

  Angiogenesis 20090101

• Effects of titanium surface roughness on mesenchymal stem cell commitment and differentiation signaling.

  The International journal of oral & maxillofacial implants 20090101

• TP53 codon 72 polymorphism and breast cancer in northern Iran.

  Oncology research 20090101

• [Neurotensine dipeptide analog dilept decreases the deficiency of prestimulus startle reflex inhibition: a prognostic sign of antipsychotic activity].

  Eksperimental'naia i klinicheskaia farmakologiia 20090101

• Identification of colorectal cancer patients with tumors carrying the TP53 mutation on the codon 72 proline allele that benefited most from 5-fluorouracil (5-FU) based postoperative chemotherapy.

  BMC cancer 20090101

• Notch2 signaling sensitizes endothelial cells to apoptosis by negatively regulating the key protective molecule survivin.

  PloS one 20090101

• Joint effects of cadmium and lead on seedlings of four Chinese cabbage cultivars in northeastern China.

  Journal of environmental sciences (China) 20090101

• The structure of monoamine oxidase from Aspergillus niger provides a molecular context for improvements in activity obtained by directed evolution.

  Journal of molecular biology 20081231

• Sequence-specific unusual (1-->2)-type helical turns in alpha/beta-hybrid peptides.

  Journal of the American Chemical Society 20081231

• Absolute side-chain structure at position 13 is required for the inhibitory activity of bromein.

  The Journal of biological chemistry 20081226

• Physical association of GPR54 C-terminal with protein phosphatase 2A.

  Biochemical and biophysical research communications 20081226

• An investigation of protonation sites and conformations of protonated amino acids by IRMPD spectroscopy.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20081222

• Conformational dynamics of minimal elastin-like polypeptides: the role of proline revealed by molecular dynamics and nuclear magnetic resonance.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20081222

• Short enantioselective syntheses of trans-5-alkylprolines from new functionalized amino alcohols.

  The Journal of organic chemistry 20081219

• Histidine kinase regulation by a cyclophilin-like inhibitor.

  Journal of molecular biology 20081212

• Inhibition of Listeria monocytogenes by oregano, cranberry and sodium lactate combination in broth and cooked ground beef systems and likely mode of action through proline metabolism.

  International journal of food microbiology 20081210

• Genetic and structural characterization of an L201P global suppressor substitution in TEM-1 beta-lactamase.

  Journal of molecular biology 20081205

• Theoretical investigations on the stereoselectivity of the proline catalyzed Mannich reaction in DMSO.

  The Journal of organic chemistry 20081205

• Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers.

  Oncogene 20081204

• The Pro12Ala polymorphism of the PPAR-gamma2 gene affects associations of fish intake and marine n-3 fatty acids with glucose metabolism.

  European journal of clinical nutrition 20081201

• Polyamines content and physiological and biochemical responses to ladder concentration of nickel stress in Hydrocharis dubia (Bl.) Backer leaves.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20081201

• Functional roles of prolines at amelogenin C terminal during tooth enamel formation.

  Cells, tissues, organs 20081201

• The orphan transporter Rxt1/NTT4 (SLC6A17) functions as a synaptic vesicle amino acid transporter selective for proline, glycine, leucine, and alanine.

  Molecular pharmacology 20081201

• A simplified model of local structure in aqueous proline amino acid revealed by first-principles molecular dynamics simulations.

  Biophysical journal 20081201

• Proline 54 trans-cis isomerization is responsible for the kinetic partitioning at the last-step photocycle of photoactive yellow protein.

  Protein science : a publication of the Protein Society 20081201

• Bifurcating fragmentation behavior of gas-phase tryptic peptide dications in collisional activation.

  Journal of the American Society for Mass Spectrometry 20081201

• Peptidomic analysis of blood plasma after in vivo treatment with protease inhibitors--a proof of concept study.

  Peptides 20081201

• Synthesis and immunosuppressive activity of new cyclolinopeptide A analogs modified with beta-prolines.

  Journal of peptide science : an official publication of the European Peptide Society 20081201

• Heightened efficacy of nitric oxide-based therapies in type II diabetes mellitus and metabolic syndrome.

  American journal of physiology. Heart and circulatory physiology 20081201

• The proline-dependent transcription factor Put3 regulates the expression of the riboflavin transporter MCH5 in Saccharomyces cerevisiae.

  Genetics 20081201

• Discovery of novel, potent and bioavailable proline-urea based macrocyclic HCV NS3/4A protease inhibitors.

  Bioorganic & medicinal chemistry letters 20081201

• Effect of the -Gly-3(S)-hydroxyprolyl-4(R)-hydroxyprolyl- tripeptide unit on the stability of collagen model peptides.

  The FEBS journal 20081201

• Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients.

  Hepatology (Baltimore, Md.) 20081201

• L-Proline as an efficient and reusable promoter for the synthesis of coumarins in ionic liquid.

  Journal of Zhejiang University. Science. B 20081201

• A novel GLRA1 mutation associated with an atypical hyperekplexia phenotype.

  Journal of child neurology 20081201

• Flexible structures and ligand interactions of tandem repeats consisting of proline, glycine, asparagine, serine, and/or threonine rich oligopeptides in proteins.

  Current protein & peptide science 20081201

• Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (PPARgamma) gene in inflammatory bowel disease.

  Journal of gastrointestinal and liver diseases : JGLD 20081201

• Investigation of abiogenic stress-induced alterations in the level of secondary metabolites in poppy plants (Papaver somniferum L.).

  Acta biologica Hungarica 20081201

• Effects of hyperbaric oxygenation on cultured barley embryos.

  Acta biologica Hungarica 20081201

• Hydroxyproline quantification for the estimation of collagen in tissue using multiple reaction monitoring mass spectrometry.

  Journal of chromatography. A 20081128

• Infrared multiple photon dissociation spectroscopy of potassiated proline.

  The journal of physical chemistry. A 20081127

• Modulation of the rate of peptidyl transfer on the ribosome by the nature of substrates.

  The Journal of biological chemistry 20081121

• A modular approach to catalyst hydrophobicity for an asymmetric aldol reaction in a biphasic aqueous environment.

  Organic & biomolecular chemistry 20081121

• Proline-directed pseudo-phosphorylation at AT8 and PHF1 epitopes induces a compaction of the paperclip folding of Tau and generates a pathological (MC-1) conformation.

  The Journal of biological chemistry 20081114

• The adaptor protein Grb2 regulates cell surface Fas ligand in Schwann cells.

  Biochemical and biophysical research communications 20081114

• Another role of proline: stabilization interactions in proteins and protein complexes concerning proline and tryptophane.

  Physical chemistry chemical physics : PCCP 20081114

• Potential nicotinic acetylcholine receptor ligands from 2,4-methanoproline derivatives.

  Journal of medicinal chemistry 20081113

• Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum.

  Structure (London, England : 1993) 20081112

• Conformational preferences of beta- and gamma-aminated proline analogues.

  The journal of physical chemistry. B 20081106

• Leucine 7 to proline 7 polymorphism in the neuropeptide Y gene and changes in serum lipids during a family-based counselling intervention among school-aged children with a family history of CVD.

  Public health nutrition 20081101

• Prolidase-dependent regulation of collagen biosynthesis.

  Amino acids 20081101

• Direct linking of metabolism and gene expression in the proline utilization A protein from Escherichia coli.

  Amino acids 20081101

• Proline metabolism in the conceptus: implications for fetal growth and development.

  Amino acids 20081101

• Human prolidase and prolidase deficiency: an overview on the characterization of the enzyme involved in proline recycling and on the effects of its mutations.

  Amino acids 20081101

• Structural biology of proline catabolism.

  Amino acids 20081101

• Proline accumulation in plants: a review.

  Amino acids 20081101

• Human Delta1-pyrroline-5-carboxylate synthase: function and regulation.

  Amino acids 20081101

• The metabolism of proline, a stress substrate, modulates carcinogenic pathways.

  Amino acids 20081101

• The importance of proline residues in the structure, stability and susceptibility to proteolytic degradation of collagens.

  Amino acids 20081101

• Introduction to second proline symposium.

  Amino acids 20081101

• Proline metabolism in health and disease. Preface.

  Amino acids 20081101

• The varitint-waddler mouse phenotypes and the TRPML3 ion channel mutation: cause and consequence.

  Pflugers Archiv : European journal of physiology 20081101

• Functional genomics and SNP analysis of human genes encoding proline metabolic enzymes.

  Amino acids 20081101

• PRODH variants and risk for schizophrenia.

  Amino acids 20081101

• The role of proline residues in the structure and function of human MT2 melatonin receptor.

  Journal of pineal research 20081101

• Polyproline derivatives as chiral selectors in high performance liquid chromatography: chromatographic and conformational studies.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081101

• Automated and simultaneous two-dimensional micro-high-performance liquid chromatographic determination of proline and hydroxyproline enantiomers in mammals.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081101

• Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism.

  Amino acids 20081101

• Influence of proline on the thermostability of the active site and membrane arrangement of transmembrane proteins.

  Biophysical journal 20081101

• Molecular dynamic simulations of nanomechanic chaperone peptide and effects of in silico His mutations on nanostructured function.

  Journal of peptide science : an official publication of the European Peptide Society 20081101

• Evidence that the amino acid residue P272 of arginine kinase is involved in its activity, structure and stability.

  International journal of biological macromolecules 20081101

• Inactivation of an aminoaldehyde dehydrogenase is responsible for fragrance in rice.

  Plant molecular biology 20081101

• Scope and limitations of the designer proline-rich antibacterial peptide dimer, A3-APO, alone or in synergy with conventional antibiotics.

  Peptides 20081101

• Analysis of HCV resistance mutations during combination therapy with protease inhibitor boceprevir and PEG-IFN alpha-2b using TaqMan mismatch amplification mutation assay.

  Journal of virological methods 20081101

• Structural basis of the differential binding of the SH3 domains of Grb2 adaptor to the guanine nucleotide exchange factor Sos1.

  Archives of biochemistry and biophysics 20081101

• The propensity for deamidation and transamidation of peptides by transglutaminase 2 is dependent on substrate affinity and reaction conditions.

  Biochimica et biophysica acta 20081101

• Proline as a stress protectant in yeast: physiological functions, metabolic regulations, and biotechnological applications.

  Applied microbiology and biotechnology 20081101

• Proteome analysis of potato under salt stress.

  Journal of proteome research 20081101

• Prolidase deficiency: the use of topical proline for treatment of leg ulcers.

  The Australasian journal of dermatology 20081101

• Misincorporation of the proline analog azetidine-2-carboxylic acid in the pathogenesis of multiple sclerosis: a hypothesis.

  Journal of neuropathology and experimental neurology 20081101

• Hepatitis C Virus NS3/4A Protease Inhibitors.

  Recent patents on anti-infective drug discovery 20081101

• Protection of capsaicin against hypoxia-reoxygenation-induced apoptosis of rat hippocampal neurons.

  Canadian journal of physiology and pharmacology 20081101

• cis-4-[(18)F]-Fluoro-l-proline fails to detect peripheral tumors in humans.

  Nuclear medicine and biology 20081101

• CEC with tris(2,2'-bipyridyl) ruthenium(II) electrochemiluminescent detection.

  Electrophoresis 20081101

• Biochemical characterization of human prolyl hydroxylase domain protein 2 variants associated with erythrocytosis.

  Biochemistry 20081028

• A novel PRNP-P105S mutation associated with atypical prion disease and a rare PrPSc conformation.

  Neurology 20081028

• A stress-dependent SUMO4 sumoylation of its substrate proteins.

  Biochemical and biophysical research communications 20081024

• Kinetic coupling of folding and prolyl isomerization of beta2-microglobulin studied by mutational analysis.

  Journal of molecular biology 20081024

• Influence of the glycosylation of human salivary proline-rich proteins on their interactions with condensed tannins.

  Journal of agricultural and food chemistry 20081022

• Function of transmembrane domain IX in the Na+/proline transporter PutP.

  Journal of molecular biology 20081017

• A second generation formal synthesis of (-)-cephalotaxine.

  The Journal of organic chemistry 20081017

• Origins of the double asymmetric induction on proline-catalyzed aldol reactions.

  The Journal of organic chemistry 20081017

• N-(p-dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide: a practical proline mimetic for facilitating enantioselective aldol reactions.

  Organic letters 20081016

• Resin-bound aminofluorescein for C-terminal labeling of peptides: high-affinity polarization probes binding to polyproline-specific GYF domains.

  Chembiochem : a European journal of chemical biology 20081013

• Metabolomics: Wine-omics.

  Nature 20081002

• Dual proline labeling protocol for individual 'baseline' and 'response' biosynthesis measurements in human articular cartilage.

  Osteoarthritis and cartilage 20081001

• Analysis of the sequence and structural features of the left-handed beta-helical fold.

  Proteins 20081001

• A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex.

  European journal of human genetics : EJHG 20081001

• A missense mutation in ALDH18A1, encoding Delta1-pyrroline-5-carboxylate synthase (P5CS), causes an autosomal recessive neurocutaneous syndrome.

  European journal of human genetics : EJHG 20081001

• A proline-to-histidine mutation in POU1F1 is associated with production traits in dairy cattle.

  Animal genetics 20081001

• Effects of chronic proline administration on lipid contents of rat brain.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20081001

• Enantiodiscrimination of bilirubin-IXalpha enantiomers in biomembrane models: has chirality a role in bilirubin toxicity?

  Bioorganic chemistry 20081001

• Ataxin-2 associates with the endocytosis complex and affects EGF receptor trafficking.

  Cellular signalling 20081001

• Physiological characterization and stress-induced metabolic responses of Dunaliella salina isolated from salt pan.

  Journal of industrial microbiology & biotechnology 20081001

• Role of NF-kappaB and PI 3-kinase/Akt in TNF-alpha-induced cytotoxicity in microvascular endothelial cells.

  American journal of physiology. Renal physiology 20081001

• The practice of ring constraint in peptidomimetics using bicyclic and polycyclic amino acids.

  Accounts of chemical research 20081001

• Electrospray ionization-ion trap mass spectrometry study of PQAAPro and PQProAA mimetic derivatives of the antimalarial primaquine.

  Journal of the American Society for Mass Spectrometry 20081001

• Design of peptidomimetic inhibitors of aspartic protease of HIV-1 containing -Phe Psi Pro- core and displaying favourable ADME-related properties.

  Journal of molecular graphics & modelling 20081001

• Osmyb4 expression improves adaptive responses to drought and cold stress in transgenic apples.

  Plant cell reports 20081001

• Lrrk2 R1628P in non-Chinese Asian races.

  Annals of neurology 20081001

• Prednisolone inhibits PDGF-induced nuclear translocation of NF-kappaB in human pulmonary artery smooth muscle cells.

  American journal of physiology. Lung cellular and molecular physiology 20081001

• Ethnicity determines association of p53Arg72Pro alleles with cervical cancer in China.

  European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20081001

• Functional region mapping of HIV-2 Vpx protein.

  Microbes and infection 20081001

• Suppression of growth and hepatic metastasis of murine B16FO melanoma cells by a novel nutrient mixture.

  Oncology reports 20081001

• A novel LMNA gene mutation Leu162Pro and the associated clinical characteristics in a family with autosomal-dominant emery-dreifuss muscular dystrophy.

  Muscle & nerve 20081001

• Roles of extensins in cotyledon primordium formation and shoot apical meristem activity in Nicotiana tabacum.

  Journal of experimental botany 20081001

• Three crystal forms of the bifunctional enzyme proline utilization A (PutA) from Bradyrhizobium japonicum.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20081001

• One amino acid difference is critical for suppression of the development of experimental autoimmune diabetes (EAD) with intravenous injection of insulinB:9-23 peptide.

  Biochemical and biophysical research communications 20080926

• Enantiomeric reversed-phase high-performance liquid chromatography resolution of D-/L-penicillamine after spirocyclization with ninhydrin and by using copper(II)-L-proline complex as a chiral selector in the mobile phase.

  Journal of chromatography. A 20080926

• Metal-triggered radial self-assembly of collagen peptide fibers.

  Journal of the American Chemical Society 20080924

• Synthesis of carbapyochelins via diastereoselective azidation of 5-(ethoxycarbonyl)methylproline derivatives.

  The Journal of organic chemistry 20080919

• Prolyl 4-hydroxylation regulates Argonaute 2 stability.

  Nature 20080918

• Proline as Lewis base catalyst: diastereoselective synthesis of isoxazoline-N-oxide through [3 + 2] cycloaddition.

  Organic letters 20080918

• A new Thr49Pro transthyretin gene mutation associated with leptomeningeal amyloidosis.

  Journal of the neurological sciences 20080915

• Endosulfan induced biochemical changes in nitrogen-fixing cyanobacteria.

  The Science of the total environment 20080915

• On-line redox speciation analysis of antimony using l-proline immobilized on controlled pore glass and hydride generation inductively coupled plasma optical emission spectrometry for detection.

  Analytica chimica acta 20080912

• Organocatalytic asymmetric synthesis of alpha,alpha-disubstituted alpha-amino acids and derivatives.

  Journal of the American Chemical Society 20080910

• Consumption of a functional fermented milk containing collagen hydrolysate improves the concentration of collagen-specific amino acids in plasma.

  Journal of agricultural and food chemistry 20080910

• 1H nuclear magnetic resonance-based metabolomic characterization of wines by grape varieties and production areas.

  Journal of agricultural and food chemistry 20080910

• A novel Na+ channel splice form contributes to the regulation of an androgen-dependent social signal.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080910

• Amino-zinc-ene-enolate cyclization: a short access to cis-3-substituted prolino-homotryptophane derivatives.

  The Journal of organic chemistry 20080905

• Copper-catalyzed synthesis of primary arylamines via cascade reactions of aryl halides with amidine hydrochlorides.

  The Journal of organic chemistry 20080905

• Intrabodies binding the proline-rich domains of mutant huntingtin increase its turnover and reduce neurotoxicity.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080903

• Transport of amino acids and GABA analogues via the human proton-coupled amino acid transporter, hPAT1: characterization of conditions for affinity and transport experiments in Caco-2 cells.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080902

• Toremifene decreases type I, type II and increases type III receptors in desmoid and fibroma and inhibits TGFbeta1 binding in desmoid fibroblasts.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080901

• Correlation between molecular mobility and crystal growth of amorphous phenobarbital and phenobarbital with polyvinylpyrrolidone and L-proline.

  Journal of pharmaceutical sciences 20080901

• Studies on search for bioactive natural products targeting TRAIL signaling leading to tumor cell apoptosis.

  Medicinal research reviews 20080901

• Morphology of the sella turcica in Axenfeld-Rieger syndrome with PITX2 mutation.

  Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20080901

• Prevention of amino acid conversion in SILAC experiments with embryonic stem cells.

  Molecular & cellular proteomics : MCP 20080901

• Correlation between Raman and X-ray crystallography data of (Pro-Pro-Gly)10.

  Biophysical chemistry 20080901

• Solution structure of a functional biomimetic and mechanistic implications for nickel superoxide dismutases.

  Chembiochem : a European journal of chemical biology 20080901

• Natural products chemistry and taxonomy of the marine cyanobacterium Blennothrix cantharidosmum.

  Journal of natural products 20080901

• Conformational dynamics of the mitochondrial ADP/ATP carrier: a simulation study.

  Molecular membrane biology 20080901

• The influence of proline isomerization and off-pathway intermediates on the folding mechanism of eukaryotic UMP/CMP Kinase.

  Journal of molecular biology 20080829

• Micellization-induced conformational change of a chiral proline surfactant.

  The journal of physical chemistry. B 20080828

• Stabilization of firefly luciferase against thermal stress by osmolytes.

  International journal of biological macromolecules 20080815

• Diversity-oriented synthesis of a drug-like system displaying the distinctive N-->C=O interaction.

  The Journal of organic chemistry 20080815

• Synthesis and biological evaluation of N-mercaptoacylproline and N-mercaptoacylthiazolidine-4-carboxylic acid derivatives as leukotriene A4 hydrolase inhibitors.

  Bioorganic & medicinal chemistry letters 20080815

• Aggregation of a proline-rich protein induced by epigallocatechin gallate and condensed tannins: effect of protein glycosylation.

  Journal of agricultural and food chemistry 20080813

• A flexible loop as a functional element in the catalytic mechanism of nucleoside hydrolase from Trypanosoma vivax.

  The Journal of biological chemistry 20080808

• Regulation of the catalytic activity and structure of human thioredoxin 1 via oxidation and S-nitrosylation of cysteine residues.

  The Journal of biological chemistry 20080808

• Roles of K+, H+, H2O, and DeltaPsi in solute transport mediated by major facilitator superfamily members ProP and LacY.

  Biochemistry 20080805

• Neuropeptide Y signal peptide Pro7 substitution protects against coronary artery atherosclerosis: the Helsinki Sudden Death Study.

  Atherosclerosis 20080801

• Competition for proline between indigenous Escherichia coli and E. coli O157:H7 in gnotobiotic mice associated with infant intestinal microbiota and its contribution to the colonization resistance against E. coli O157:H7.

  Antonie van Leeuwenhoek 20080801

• Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution.

  Proteins 20080801

• Structural characterization and reactivity of gamma-octamolybdate functionalized by proline.

  Journal of inorganic biochemistry 20080801

• Phosphoenolpyruvate-dependent inhibition of collagen biosynthesis, alpha2beta1 integrin and IGF-I receptor signaling in cultured fibroblasts.

  Molecular and cellular biochemistry 20080801

• Comparative physiological and molecular responses of a common aromatic indica rice cultivar to high salinity with non-aromatic indica rice cultivars.

  Plant cell reports 20080801

• The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma2 gene is associated with plasma levels of soluble RAGE (Receptor for Advanced Glycation Endproducts) and the presence of peripheral arterial disease.

  Clinical biochemistry 20080801

• Molecular interactions of alanine-rich and proline-rich regions of cell surface protein antigen c in Streptococcus mutans.

  Oral microbiology and immunology 20080801

• Structural basis of the transcriptional regulation of the proline utilization regulon by multifunctional PutA.

  Journal of molecular biology 20080801

• Enhancement of spermidine content and antioxidant capacity in transgenic pear shoots overexpressing apple spermidine synthase in response to salinity and hyperosmosis.

  Phytochemistry 20080801

• Adaptation to a long term (4 weeks) arginine- and precursor (glutamate, proline and aspartate)-free diet.

  Clinical nutrition (Edinburgh, Scotland) 20080801

• Synthesis and structure-activity relationships of potent 1-(2-substituted-aminoacetyl)-4-fluoro-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors.

  Chemical & pharmaceutical bulletin 20080801

• [Association of the Pro12Ala and C1431T polymorphism of the PPAR gamma2 gene and their haplotypes with obesity and type 2 diabetes].

  Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20080801

• [Selective determination of norepinephrine by a cyclic voltammetric method using poly-proline-modified electrodes].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080801

• Regulatory effect of hydrogen sulfide on vascular collagen content in spontaneously hypertensive rats.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080801

• The effect of water stress on the antioxidant content, protective enzyme activities, proline content and lipid peroxidation in wheat seedling.

  Pakistan journal of biological sciences : PJBS 20080801

• Alterations of the gene expression, lipid peroxidation, proline and thiol content along the barley root exposed to cadmium.

  Journal of plant physiology 20080731

• Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome.

  The Journal of biological chemistry 20080725

• Dynamics and cooperativity of Trp-cage folding.

  Archives of biochemistry and biophysics 20080715

• Hepatitis C virus NS3-4A serine protease inhibitors: SAR of new P1 derivatives of SCH 503034.

  Bioorganic & medicinal chemistry letters 20080715

• [Research of signaling pathway of vascular endothelial growth factor regulating by hepatitis B virus X protein].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20080715

• [The 43rd Annual Meeting of the European Association for the Study of the Liver (EASL), Milan, Italy, April 23-27, 2008].

  Orvosi hetilap 20080713

• The structure and interactions of the proline-rich domain of ASPP2.

  The Journal of biological chemistry 20080704

• Improved protocol for asymmetric, intramolecular heteroatom Michael addition using organocatalysis: enantioselective syntheses of homoproline, pelletierine, and homopipecolic acid.

  The Journal of organic chemistry 20080704

• Pyrrole-2-carboxylic acid as a ligand for the Cu-catalyzed reactions of primary anilines with aryl halides.

  The Journal of organic chemistry 20080704

• Stepwise hydration of protonated proline.

  The journal of physical chemistry. B 20080703

• Inhibitory effect of zinc on hypoxic HIF-1 activation in astrocytes.

  Neuroreport 20080702

• Central carbon metabolism in the progression of mammary carcinoma.

  Breast cancer research and treatment 20080701

• Bacterial selectivity and plausible mode of antibacterial action of designed Pro-rich short model antimicrobial peptides.

  Journal of peptide science : an official publication of the European Peptide Society 20080701

• Thermodynamic and spectroscopic studies of Cu(II) and Ni(II) complexes with a new proline-threonine dipeptide ligand.

  Journal of inorganic biochemistry 20080701

• A high-throughput screening method for small-molecule pharmacologic chaperones of misfolded rhodopsin.

  Investigative ophthalmology & visual science 20080701

• The molecular mechanisms of the attenuation of cisplatin-induced acute renal failure by N-acetylcysteine in rats.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080701

• Alternative stabilities of a proline-rich antibacterial peptide in vitro and in vivo.

  Protein science : a publication of the Protein Society 20080701

• Structures, fragmentation, and protonation of trideoxynucleotide CCC mono- and dianions.

  Journal of the American Society for Mass Spectrometry 20080701

• Effects of cardiotonic steroids on dermal collagen synthesis and wound healing.

  Journal of applied physiology (Bethesda, Md. : 1985) 20080701

• 24-Epibrassinolide protects against the stress generated by salinity and nickel in Brassica juncea.

  Chemosphere 20080701

• Elasticity of spider silks.

  Biomacromolecules 20080701

• Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro.

  The American journal of pathology 20080701

• Synthesis and biological activity of endomorphin-2 analogs incorporating piperidine-2-, 3- or 4-carboxylic acids instead of proline in position 2.

  Chemical biology & drug design 20080701

• The proline-rich sequence of CD3epsilon as an amplifier of low-avidity TCR signaling.

  Journal of immunology (Baltimore, Md. : 1950) 20080701

• alpha,alpha'-disubstituted amino acids with silylated side chains as lipophilic building blocks for the synthesis of peptaibol analogues.

  Chemistry & biodiversity 20080701

• Melasma: successful treatment with pidobenzone 4% (K5lipogel).

  Dermatologic therapy 20080701

• A nutrient mixture suppresses carbon tetrachloride-induced acute hepatic toxicity in ICR mice.

  Human & experimental toxicology 20080701

• The thymine-DNA glycosylase regulatory domain: residual structure and DNA binding.

  Biochemistry 20080624

• Intramolecular Nicholas reaction: stereoselective synthesis of 5-alkynylproline derivatives.

  Organic letters 20080619

• Transmembrane domain interactions and residue proline 378 are essential for proper structure, especially disulfide bond formation, in the human vitamin K-dependent gamma-glutamyl carboxylase.

  Biochemistry 20080617

• Treatment with salicylic acid decreases the effect of cadmium on photosynthesis in maize plants.

  Journal of plant physiology 20080616

• Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells.

  The Journal of biological chemistry 20080613

• Glucose-induced remodeling of intermediary and energy metabolism in procyclic Trypanosoma brucei.

  The Journal of biological chemistry 20080613

• Microglial activation in brain lesions with tau deposits: comparison of human tauopathies and tau transgenic mice TgTauP301L.

  Brain research 20080612

• Beta3 integrin haplotype influences gene regulation and plasma von Willebrand factor activity.

  Atherosclerosis 20080601

• Polymorphisms of TP53 Arg72Pro, but not p73 G4C14>A4TA4 and p21 Ser31Arg, contribute to risk of cutaneous melanoma.

  The Journal of investigative dermatology 20080601

• Asymmetric synthesis of bicyclic piperidines via L-proline catalyzed aldol reaction of 3-phthalimidopropanal.

  Chirality 20080601

• Antitumor effects, cell selectivity and structure-activity relationship of a novel antimicrobial peptide polybia-MPI.

  Peptides 20080601

• The in vivo phosphorylation sites in multiple isoforms of amphiphysin I from rat brain nerve terminals.

  Molecular & cellular proteomics : MCP 20080601

• L-Proline uptake in Crithidia deanei is influenced by its endosymbiont bacterium.

  FEMS microbiology letters 20080601

• Differential gene expression analysis of maize leaf at heading stage in response to water-deficit stress.

  Bioscience reports 20080601

• Myenteric neurons of the ileum that express somatostatin are a target of prion neuroinvasion in an alimentary model of sheep scrapie.

  Acta neuropathologica 20080601

• Potent triazolyl-proline-based inhibitors of HCV NS3 protease.

  Bioorganic & medicinal chemistry letters 20080601

• Metabolomic profiling using Orbitrap Fourier transform mass spectrometry with hydrophilic interaction chromatography: a method with wide applicability to analysis of biomolecules.

  Rapid communications in mass spectrometry : RCM 20080601

• Effect of chromium species on phytochemical and physiological parameters in Datura innoxia.

  Chemosphere 20080601

• Hepatitis C protease and polymerase inhibitors in development.

  AIDS patient care and STDs 20080601

• PRGL: A cell wall proline-rich protein containning GASA domain in Gerbera hybrida.

  Science in China. Series C, Life sciences 20080601

• Osmoregulation and antioxidant metabolism in drought-stressed Helianthus annuus under triadimefon drenching.

  Comptes rendus biologies 20080601

• Combined effects of long-term salinity and soil drying on growth, water relations, nutrient status and proline accumulation of Sesuvium portulacastrum.

  Comptes rendus biologies 20080601

• A functional proline switch in cytochrome P450cam.

  Structure (London, England : 1993) 20080601

• The effect of proline on the network structure of major ampullate silks as inferred from their mechanical and optical properties.

  The Journal of experimental biology 20080601

• The role of proline in the elastic mechanism of hydrated spider silks.

  The Journal of experimental biology 20080601

• Modular organization and combinatorial energetics of proline-tyrosine nuclear localization signals.

  PLoS biology 20080601

• Production of teicoplanin from Actinoplanes teichomyceticus ID9303 by adding proline.

  Bioscience, biotechnology, and biochemistry 20080601

• Response of growth and antioxidant enzymes in Azolla plants (Azolla pinnata and Azolla filiculoides) exposed to UV-B.

  Acta biologica Hungarica 20080601

• Heat stress protection in Aspen sp1 transgenic Arabidopsis thaliana.

  BMB reports 20080531

• Catalytic, asymmetric transannular aldolizations: total synthesis of (+)-hirsutene.

  Journal of the American Chemical Society 20080528

• The best disease-linked Cl- channel hBest1 regulates Ca V 1 (L-type) Ca2+ channels via src-homology-binding domains.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080528

• Proline and glycinebetaine enhance antioxidant defense and methylglyoxal detoxification systems and reduce NaCl-induced damage in cultured tobacco cells.

  Journal of plant physiology 20080526

• Evidence that proline focuses movement of the floppy loop of arylalkylamine N-acetyltransferase (EC 2.3.1.87).

  The Journal of biological chemistry 20080523

• Enantiomeric separation of alcohols and amines on a proline chiral stationary phase by gas chromatography.

  Journal of chromatography. A 20080516

• Benzyl 2-cyano-3,3-dimethyl-1-pyrrolidinecarboxylate, a versatile intermediate for the synthesis of 3,3-dimethylproline derivatives.

  The Journal of organic chemistry 20080516

• Proline-catalyzed direct inverse electron demand diels-alder reactions of ketones with 1,2,4,5-tetrazines.

  Organic letters 20080515

• Proline and gamma-carboxylated glutamate residues in matrix Gla protein are critical for binding of bone morphogenetic protein-4.

  Circulation research 20080509

• Proline-rich proteins--deriving a basis for residue-based selectivity in polyphenolic binding.

  Organic & biomolecular chemistry 20080507

• Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division.

  The Journal of cell biology 20080505

• Chiral separation of selected proline derivatives using a polysaccharide-type stationary phase by supercritical fluid chromatography and comparison with high-performance liquid chromatography.

  Journal of chromatography. A 20080502

• CKIalpha is associated with and phosphorylates star-PAP and is also required for expression of select star-PAP target messenger RNAs.

  The Journal of biological chemistry 20080502

• Conformational preferences of alpha-substituted proline analogues.

  The Journal of organic chemistry 20080502

• Proline derived spirobarbiturates as highly effective beta-turn mimetics incorporating polar and functionalizable constraint elements.

  The Journal of organic chemistry 20080502

• C(alpha)-methyl proline: a unique example of split personality.

  Biopolymers 20080501

• 4-chloroprolines: synthesis, conformational analysis, and effect on the collagen triple helix.

  Biopolymers 20080501

• The proline-rich domain in p63 is necessary for the transcriptional and apoptosis-inducing activities of TAp63.

  Oncogene 20080501

• Design, synthesis, conformational and membrane ion transport studies of proline-adamantane hybrid cyclic depsipeptides.

  Biopolymers 20080501

• Spermatogenic and steroidogenic impairment of the testicle characterizes the hereditary leucine-75-proline apolipoprotein a-I amyloidosis.

  The Journal of clinical endocrinology and metabolism 20080501

• Prolene-Monocryl-composite meshes do not increase microvascular Staphylococcus aureus adherence and do not sensitize for leukocytic inflammation.

  Langenbeck's archives of surgery 20080501

• Cataract mutation P20S of alphaB-crystallin impairs chaperone activity of alphaA-crystallin and induces apoptosis of human lens epithelial cells.

  Biochimica et biophysica acta 20080501

• Gene expression profiles and intracellular contents of stress protectants in Saccharomyces cerevisiae under ethanol and sorbitol stresses.

  Applied microbiology and biotechnology 20080501

• The mutation p.Ser298Pro in the sulphamidase gene (SGSH) is associated with a slowly progressive clinical phenotype in mucopolysaccharidosis type IIIA (Sanfilippo A syndrome).

  Human mutation 20080501

• The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes.

  Nature immunology 20080501

• Concise, stereoselective route to the four diastereoisomers of 4-methylproline.

  Journal of natural products 20080501

• Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034.

  Journal of synchrotron radiation 20080501

• Reduced amelogenin-MMP20 interactions in amelogenesis imperfecta.

  Journal of dental research 20080501

• Increased expression and cell surface localization of MT1-MMP plays a role in stimulation of MMP-2 activity by leptin in neonatal rat cardiac myofibroblasts.

  Journal of molecular and cellular cardiology 20080501

• Atorvastatin downregulates BMP-2 expression induced by oxidized low-density lipoprotein in human umbilical vein endothelial cells.

  Circulation journal : official journal of the Japanese Circulation Society 20080501

• Structural plasticity underpins promiscuous binding of the prosurvival protein A1.

  Structure (London, England : 1993) 20080501

• Live single-cell molecular analysis by video-mass spectrometry.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080501

• Binocular phasic coactivation does not prevent ocular dominance segregation.

  Frontiers in bioscience : a journal and virtual library 20080501

• [Correlations between leaf delta13C and physiological parameters of desert plant Reaumuria soongorica].

  Ying yong sheng tai xue bao = The journal of applied ecology 20080501

• Enantioselective organocatalytic Michael addition of aldehydes to nitroethylene: efficient access to gamma2-amino acids.

  Journal of the American Chemical Society 20080430

• Peptide catalyzed asymmetric conjugate addition reactions of aldehydes to nitroethylene--a convenient entry into gamma2-amino acids.

  Journal of the American Chemical Society 20080430

• Comparative salt tolerance analysis between Arabidopsis thaliana and Thellungiella halophila, with special emphasis on K(+)/Na(+) selectivity and proline accumulation.

  Journal of plant physiology 20080418

• Characterization of a novel Caenorhabditis elegans prolyl 4-hydroxylase with a unique substrate specificity and restricted expression in the pharynx and excretory duct.

  The Journal of biological chemistry 20080418

• Short alpha/beta-peptides as catalysts for intra- and intermolecular aldol reactions.

  The Journal of organic chemistry 20080418

• Ruthenium-catalyzed one-pot carbenoid N-H insertion reactions and diastereoselective synthesis of prolines.

  Organic letters 20080417

• Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers.

  The Biochemical journal 20080415

• Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter.

  Biochemical pharmacology 20080415

• A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation.

  Journal of immunology (Baltimore, Md. : 1950) 20080415

• Proline-glutamic acid-proline-lysine repetition peptide as an antigen for the serological diagnosis of strangles.

  The Veterinary record 20080412

• Molecular mechanisms of cryoprotection in aqueous proline: light scattering and molecular dynamics simulations.

  The journal of physical chemistry. B 20080410

• A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.

  Journal of molecular biology 20080404

• Proline-mediated enantioselective construction of tetrahydropyrans via a domino aldol/acetalization reaction.

  Organic letters 20080403

• A new sparteine surrogate for asymmetric deprotonation of N-Boc pyrrolidine.

  Organic letters 20080403

• Overexpression of a TFIIIA-type zinc finger protein gene ZFP252 enhances drought and salt tolerance in rice (Oryza sativa L.).

  FEBS letters 20080402

• Immunohistochemical study of the pre- and postnatal innervation of the dog lower urinary tract: morphological aspects at the basis of the consolidation of the micturition reflex.

  Veterinary research communications 20080401

• Mouse strain-specific coding polymorphism in the Slc4a2/Ae2 gene encodes Ae2c2 variants differing in isoform-specific dominant negative activity.

  Experimental physiology 20080401

• Wide turn diversity in protein transmembrane helices implications for G-protein-coupled receptor and other polytopic membrane protein structure and function.

  Molecular pharmacology 20080401

• The 7-amino-acid site in the proline-rich region of the N-terminal domain of p53 is involved in the interaction with FAK and is critical for p53 functioning.

  The Biochemical journal 20080401

• Mutational analysis of histidine residues in the human proton-coupled amino acid transporter PAT1.

  Biochimica et biophysica acta 20080401

• A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis.

  Bone 20080401

• Association of missense variants of the PRKC, apoptosis, WT1, regulator (PAWR) gene with schizophrenia.

  Progress in neuro-psychopharmacology & biological psychiatry 20080401

• Lung cancer risk associated with Thr495Pro polymorphism of GHR in Chinese population.

  Japanese journal of clinical oncology 20080401

• Role of genetic background in determining phenotypic severity throughout postnatal development and at peak bone mass in Col1a2 deficient mice (oim).

  Bone 20080401

• Antioxidant enzymatic activity is linked to waterlogging stress tolerance in citrus.

  Physiologia plantarum 20080401

• Evaluation of the transforming growth factor beta1 codon 25 (Arg-->Pro) polymorphism in alcoholic liver disease.

  Cytokine 20080401

• Cardiovascular disease-risk factors in middle-aged osteopaenic women treated with calcium alone or combined to three nutrients essential to artery and bone collagen.

  Journal of human nutrition and dietetics : the official journal of the British Dietetic Association 20080401

• Metachromatic leukodystrophy: genetics, pathogenesis and therapeutic options.

  Acta paediatrica (Oslo, Norway : 1992) 20080401

• Synthesis of novel spiropyrrolizidines as potent antimicrobial agents for human and plant pathogens.

  Bioorganic & medicinal chemistry letters 20080401

• Matched regulation of gastrointestinal performance in the Burmese python, Python molurus.

  The Journal of experimental biology 20080401

• Radiosynthesis and ex vivo evaluation of [11C]-SIB-1553A as a PET radiotracer for beta4 selective subtype nicotinic acetylcholine receptor.

  Nuclear medicine and biology 20080401

• N-acetyl D-glucosamine stimulates growth in procyclic forms of Trypanosoma brucei by inducing a metabolic shift.

  Parasitology 20080401

• NADPH-dependent glutamate dehydrogenase in Penicillium chrysogenum is involved in regulation of beta-lactam production.

  Microbiology (Reading, England) 20080401

• Rat wild-type parathyroid hormone receptor (PTH-R) and mutant PTH-R(P132L) show the different intracellular localization in vitro.

  Biomedical research (Tokyo, Japan) 20080401

• Effect of osmolytes on the conformational stability of mouse monoclonal antidigoxin antibody in long-term storage.

  Hybridoma (2005) 20080401

• Proline-catalysed Mannich reactions of acetaldehyde.

  Nature 20080327

• Discovery of subnanomolar arginine-glycine-aspartate-based alphaVbeta3/alphaVbeta5 integrin binders embedding 4-aminoproline residues.

  Journal of medicinal chemistry 20080327

• A mild and general method for the synthesis of 5-substituted and 5,5-disubstituted fulleroprolines.

  Organic letters 20080320

• Modeling the solvation of peptides. The case of (s)-N-acetylproline amide in liquid water.

  The journal of physical chemistry. B 20080320

• The rate enhancement for prolyl cis-to-trans isomerization of cyclic CPFC peptide is caused by an increase in the vibrational entropy of the transition state.

  The journal of physical chemistry. B 20080320

• Tissue distribution in mice of BPP 10c, a potent proline-rich anti-hypertensive peptide of Bothrops jararaca.

  Toxicon : official journal of the International Society on Toxinology 20080315

• The mouse and human Ah receptor differ in recognition of LXXLL motifs.

  Archives of biochemistry and biophysics 20080315

• Chemical stress induced by heliotrope (Heliotropium europaeum L.) allelochemicals and increased activity of antioxidant enzymes.

  Pakistan journal of biological sciences : PJBS 20080315

• Analysis of the thermodynamics of binding of an SH3 domain to proline-rich peptides using a chimeric fusion protein.

  Journal of molecular biology 20080314

• Aluminum tolerance in maize is correlated with increased levels of mineral nutrients, carbohydrates and proline, and decreased levels of lipid peroxidation and Al accumulation.

  Journal of plant physiology 20080313

• Essential role of Pyk2 and Src kinase activation in neuropeptide-induced proliferation of small cell lung cancer cells.

  Oncogene 20080313

• Azetidine-derived amino acids versus proline derivatives. alternative trends in reverse turn induction.

  The Journal of organic chemistry 20080307

• Cell death signal by glycine- and proline-rich plant glycoprotein is transferred from cytochrome c and nuclear factor kappa B to caspase 3 in Hep3B cells.

  The Journal of nutritional biochemistry 20080301

• Lack of association between the Pro12Ala polymorphism of the PPAR-gamma 2 gene and type 2 diabetes mellitus in the Qatari consanguineous population.

  Acta diabetologica 20080301

• Structural and functional characterization of the porcine proline-rich antifungal peptide SP-B isolated from salivary gland granules.

  Journal of peptide science : an official publication of the European Peptide Society 20080301

• gamma-Zein secondary structure in solution by circular dichroism.

  Biopolymers 20080301

• TLR4 signaling induces functional nerve growth factor receptor p75NTR on mouse dendritic cells via p38MAPK and NF-kappa B pathways.

  Molecular immunology 20080301

• Localization of post-proline cleaving peptidases in Tenebrio molitor larval midgut.

  Biochimie 20080301

• Impact of proline and aspartic acid residues on the dissociation of intermolecularly crosslinked peptides.

  Journal of the American Society for Mass Spectrometry 20080301

• Proline-rich, amphipathic cell-penetrating peptides.

  Advanced drug delivery reviews 20080301

• Stylopeptide 2, a proline-rich cyclodecapeptide from the sponge Stylotella sp.

  Journal of natural products 20080301

• Characterization of resistance mutations against HCV ketoamide protease inhibitors.

  Antiviral research 20080301

• The Trp-cage: optimizing the stability of a globular miniprotein.

  Protein engineering, design & selection : PEDS 20080301

• Analysis of the cell adhesion molecule sticks-and-stones reveals multiple redundant functional domains, protein-interaction motifs and phosphorylated tyrosines that direct myoblast fusion in Drosophila melanogaster.

  Genetics 20080301

• Copper-induced proline synthesis is associated with nitric oxide generation in Chlamydomonas reinhardtii.

  Plant & cell physiology 20080301

• The role of metals in modulating metalloprotease activity in the AD brain.

  European biophysics journal : EBJ 20080301

• Prognostic impact of p53 Pro72 homozygous genotype in non-small cell lung cancer patients.

  Oncology reports 20080301

• Large-scale characterization of natural ligands explains the unique gluten-binding properties of HLA-DQ2.

  Journal of immunology (Baltimore, Md. : 1950) 20080301

• [Proline functions and its metabolic regulations in yeast: relevance to stress adaptation-strategy].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20080301

• Glucocerebrosidase gene mutations: a risk factor for Lewy body disorders.

  Archives of neurology 20080301

• Clinical manifestation of a novel PAX6 mutation Arg128Pro.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20080301

• Novel functions of ubiquitin ligase HRD1 with transmembrane and proline-rich domains.

  Journal of pharmacological sciences 20080301

• A nutrient mixture prevents acetaminophen hepatic and renal toxicity in ICR mice.

  Human & experimental toxicology 20080301

• Protective and therapeutic effects of glyprolines in psychoemotional stress induced by cholecystokinin-4 injection.

  Bulletin of experimental biology and medicine 20080301

• The nucleoid binding protein H-NS acts as an anti-channeling factor to favor intermolecular Tn10 transposition and dissemination.

  Journal of molecular biology 20080227

• Functional role of the conserved proline in helix 6 of the human bradykinin B2 receptor.

  Biochemical and biophysical research communications 20080222

• Peptidyl-prolyl-tRNA at the ribosomal P-site reacts poorly with puromycin.

  Biochemical and biophysical research communications 20080222

• Role of Ser-340 and Thr-341 in transmembrane domain IX of the Na+/proline transporter PutP of Escherichia coli in ligand binding and transport.

  The Journal of biological chemistry 20080222

• Elaboration of 2-(trifluoromethyl)indoles via a cascade coupling/condensation/deacylation process.

  Organic letters 20080221

• Potent and selective small molecule NS3 serine protease inhibitors of Hepatitis C virus with dichlorocyclopropylproline as P2 residue.

  Bioorganic & medicinal chemistry 20080215

• Proline modulates the intracellular redox environment and protects mammalian cells against oxidative stress.

  Free radical biology & medicine 20080215

• Design of azidoproline containing gluten peptides to suppress CD4+ T-cell responses associated with celiac disease.

  Bioorganic & medicinal chemistry 20080215

• Glucocerebrosidase gene mutations are associated with Parkinson's disease in southern Italy.

  Movement disorders : official journal of the Movement Disorder Society 20080215

• Effects of tanshinone VI on phosphorylation of ERK and Akt in isolated cardiomyocytes and cardiac fibroblasts.

  European journal of pharmacology 20080212

• Diacylglycerol kinase-alpha phosphorylation by Src on Y335 is required for activation, membrane recruitment and Hgf-induced cell motility.

  Oncogene 20080207

• Debromodispacamides B and D: isolation from the marine sponge Agelas mauritiana and stereoselective synthesis using a biomimetic proline route.

  Organic letters 20080207

• Effective nonenzymatic kinetic resolution of racemic m-nitro-substituted inherently chiral aminocalix[4]arenes.

  Organic letters 20080207

• Free radical scavenging potential of L-proline: evidence from in vitro assays.

  Amino acids 20080201

• Nutrient mixture including vitamin C, L-lysine, L-proline, and epigallocatechin is ineffective against tumor growth and metastasis in a syngeneic neuroblastoma model.

  Pediatric blood & cancer 20080201

• Salt tolerance conferred by overexpression of Arabidopsis vacuolar Na(+)/H (+) antiporter gene AtNHX1 in common buckwheat (Fagopyrum esculentum).

  Transgenic research 20080201

• Auditory nerve is affected in one of two different point mutations of the neurofilament light gene.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20080201

• The RIZ Pro704 insertion-deletion polymorphism, bone mineral density and fracture risk: the Rotterdam study.

  Bone 20080201

• Modulation of intracellular proline levels affects flowering time and inflorescence architecture in Arabidopsis.

  Plant molecular biology 20080201

• Micronutrient mixture in tumor growth and metastasis.

  Pediatric blood & cancer 20080201

• In silico screening and biological evaluation of inhibitors of Src-SH3 domain interaction with a proline-rich ligand.

  Bioorganic & medicinal chemistry letters 20080201

• Protected aminooxyprolines for expedited library synthesis: application to Tsg101-directed proline-oxime containing peptides.

  Bioorganic & medicinal chemistry letters 20080201

• Direct asymmetric alpha-amination of cyclic ketones catalyzed by siloxyproline.

  Chemistry, an Asian journal 20080201

• Quantum mechanical design of enzyme active sites.

  The Journal of organic chemistry 20080201

• Peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism, cod liver oil and risk of type 1 diabetes.

  Pediatric diabetes 20080201

• Relationship between carbachol hyperstimulation-induced pancreatic intracellular trypsinogen and NF-kappa B activation in rats in vitro.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20080201

• Possible involvement of put A gene in Helicobacter pylori colonization in the stomach and motility.

  Biomedical research (Tokyo, Japan) 20080201

• [Effects of cadmium on the growth and nitrogen metabolism in Brassica chinensis].

  Huan jing ke xue= Huanjing kexue 20080201

• Role of soybean GmbZIP132 under abscisic acid and salt stresses.

  Journal of integrative plant biology 20080201

• A beta-hairpin comprising the nuclear localization sequence sustains the self-associated states of nucleosome assembly protein 1.

  Journal of molecular biology 20080125

• Catalysis of 3-pyrrolidinecarboxylic acid and related pyrrolidine derivatives in enantioselective anti-Mannich-type reactions: importance of the 3-acid group on pyrrolidine for stereocontrol.

  Journal of the American Chemical Society 20080123

• Naturally occurring NS3-protease-inhibitor resistant mutant A156T in the liver of an untreated chronic hepatitis C patient.

  Virology 20080120

• A convenient synthesis of substituted pyrazolidines and azaproline derivatives through highly regio- and diastereoselective reduction of 2-pyrazolines.

  The Journal of organic chemistry 20080118

• Toward an artificial aldolase.

  Organic letters 20080117

• Complexes of mutants of Escherichia coli aminopeptidase P and the tripeptide substrate ValProLeu.

  Archives of biochemistry and biophysics 20080115

• Distinct structural requirements of GATA-3 for the regulation of thymocyte and Th2 cell differentiation.

  Journal of immunology (Baltimore, Md. : 1950) 20080115

• Exclusion of the native alpha-helix from the amyloid fibrils of a mixed alpha/beta protein.

  Journal of molecular biology 20080111

• Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.

  Biochemistry 20080108

• High-resolution structural analysis of mammalian profilin 2a complex formation with two physiological ligands: the formin homology 1 domain of mDia1 and the proline-rich domain of VASP.

  Journal of molecular biology 20080104

• PPAR-gamma Pro12Ala genotype and risk of cognitive decline in elders.

  Neurobiology of aging 20080101

• Influence of salinity on the in vitro development of Glomus intraradices and on the in vivo physiological and molecular responses of mycorrhizal lettuce plants.

  Microbial ecology 20080101

• 28-homobrassinolide protects chickpea (Cicer arietinum) from cadmium toxicity by stimulating antioxidants.

  Environmental pollution (Barking, Essex : 1987) 20080101

• Fasciola gigantica: enzymes of the ornithine-proline-glutamate pathway--characterization of delta1-pyrroline-5-carboxylate dehydrogenase.

  Experimental parasitology 20080101

• Protective effect of hyaluronic acid on interleukin-1-induced deregulation of beta1-integrin and insulin-like growth factor-I receptor signaling and collagen biosynthesis in cultured human chondrocytes.

  Molecular and cellular biochemistry 20080101

• c[D-pro-Pro-D-pro-N-methyl-Ala] adopts a rigid conformation that serves as a scaffold to mimic reverse-turns.

  Biopolymers 20080101

• Discovery of long-acting N-(cyanomethyl)-N-alkyl-L-prolinamide inhibitors of dipeptidyl peptidase IV.

  Bioorganic & medicinal chemistry 20080101

• Duplicated P5CS genes of Arabidopsis play distinct roles in stress regulation and developmental control of proline biosynthesis.

  The Plant journal : for cell and molecular biology 20080101

• Total syntheses of carbohydrates: organocatalyzed aldol additions of dihydroxyacetone.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Sensing the chirality of Dawson lanthanide polyoxometalates [alpha1-LnP2W17O61]7- by multinuclear NMR spectroscopy.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Beneficial effect of a short-acting NO donor for the prevention of neointimal hyperplasia.

  Free radical biology & medicine 20080101

• Proline and processing of spider silks.

  Biomacromolecules 20080101

• Salt stress increases the expression of p5cs gene and induces proline accumulation in cactus pear.

  Plant physiology and biochemistry : PPB 20080101

• Reshaping the folding energy landscape of human carbonic anhydrase II by a single point genetic mutation Pro237His.

  The international journal of biochemistry & cell biology 20080101

• Does trypsin cut before proline?

  Journal of proteome research 20080101

• TP53 codon 72 polymorphism in susceptibility, overall survival, and adjuvant therapy response of gliomas.

  Cancer genetics and cytogenetics 20080101

• Functional mapping of apidaecin through secondary structure correlation.

  The international journal of biochemistry & cell biology 20080101

• Functional asymmetry of the conserved cystine loops in alphabetagamma GABA A receptors revealed by the response to GABA activation and drug potentiation.

  The international journal of biochemistry & cell biology 20080101

• What causes paramyotonia in the United Kingdom? Common and new SCN4A mutations revealed.

  Neurology 20080101

• Nitric oxide and nanotechnology: a novel approach to inhibit neointimal hyperplasia.

  Journal of vascular surgery 20080101

• A proline-rich polypeptide from ovine colostrum: colostrinin with immunomodulatory activity.

  Advances in experimental medicine and biology 20080101

• Challenges in modern drug discovery: a case study of boceprevir, an HCV protease inhibitor for the treatment of hepatitis C virus infection.

  Accounts of chemical research 20080101

• Inhibition of 7,12-dimethylbenzanthracene-induced skin tumors by a nutrient mixture.

  Medical oncology (Northwood, London, England) 20080101

• Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens.

  Chemistry & biology 20080101

• FGFR mutations and plagiocephaly.

  The Journal of craniofacial surgery 20080101

• Conformational properties of 4-mercaptoproline and related derivatives.

  Angewandte Chemie (International ed. in English) 20080101

• Phenotype associated with the H626P mutation and other changes in the TGFBI gene in Czech families.

  Ophthalmic research 20080101

• Advances in matrix metalloproteinase inhibitors based on pyrrolidine scaffold.

  Current medicinal chemistry 20080101

• Synthetic biology of proteins: tuning GFPs folding and stability with fluoroproline.

  PloS one 20080101

• Connective tissue metabolism in chikungunya patients.

  Virology journal 20080101

• Stabilization of beta-propeller phytase by introducing Xaa-->Pro and Gly-->Ala substitutions at consensus positions.

  Protein and peptide letters 20080101

• [Relations of the causative agents of plague and listeriosis during their simultaneous stay in the flea Citellophilus tesquorum at different environmental temperatures].

  Meditsinskaia parazitologiia i parazitarnye bolezni 20080101

• An inland and a coastal population of the Mediterranean xero-halophyte species Atriplex halimus L. differ in their ability to accumulate proline and glycinebetaine in response to salinity and water stress.

  Journal of experimental botany 20080101

• Changes in foliar proline concentration of osmotically stressed barley.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

• Highly enantioselective strecker reaction of ketoimines catalyzed by an organocatalyst from (S)-BINOL and L-prolinamide.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Diphenylprolinol silyl ether as a catalyst in an enantioselective, catalytic, formal aza [3+3] cycloaddition reaction for the formation of enantioenriched piperidines.

  Angewandte Chemie (International ed. in English) 20080101

• Ser80Ile mutation and a concurrent Pro25Leu variant of the VHL gene in an extended Hungarian von Hippel-Lindau family.

  BMC medical genetics 20080101

• Ornithine-delta-aminotransferase is essential for arginine catabolism but not for proline biosynthesis.

  BMC plant biology 20080101

• Solid-phase combinatorial synthesis of a lysyl-tRNA synthetase (LysRS) inhibitory library.

  Journal of combinatorial chemistry 20080101

• Asymmetric Michael reaction of acetaldehyde catalyzed by diphenylprolinol silyl ether.

  Angewandte Chemie (International ed. in English) 20080101

• P35S mutation in the NOG gene associated with Teunissen-Cremers syndrome and features of multiple NOG joint-fusion syndromes.

  European journal of medical genetics 20080101

• Catalytic asymmetric Michael reactions of acetaldehyde.

  Angewandte Chemie (International ed. in English) 20080101

• Proline-linked nitrosoureas as prolidase-convertible prodrugs in human breast cancer cells.

  Pharmacological reports : PR 20080101

• Click chemistry approach to assembly proline mimetic libraries containing 1,4-substituted 1,2,3-triazoles.

  Journal of combinatorial chemistry 20080101

• Proline-rich sequence recognition domains (PRD): ligands, function and inhibition.

  Handbook of experimental pharmacology 20080101

• Designed peptides with homochiral and heterochiral diproline templates as conformational constraints.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Binding of tripeptide Pro-Gly-Pro labeled at the C-terminal proline residue to plasma membranes of the rat forebrain.

  Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20080101

• HIV-1 Tat protein alter the tight junction integrity and function of retinal pigment epithelium: an in vitro study.

  BMC infectious diseases 20080101

• Phytotoxicity of cadmium on protein, proline and antioxidant enzyme activities in growing Arachis hypogaea L. seedlings.

  Journal of environmental sciences (China) 20080101

• Synthesis of trifluoromethyl-substituted proline analogues as 19F NMR labels for peptides in the polyproline II conformation.

  Angewandte Chemie (International ed. in English) 20080101

• A mutation in GJA8 (p.P88Q) is associated with 'balloon-like' cataract with Y-sutural opacities in a family of Indian origin.

  Molecular vision 20080101

• Binding to the minor groove of the double-strand, tau protein prevents DNA from damage by peroxidation.

  PloS one 20080101

• Role of p53 codon 72 arginine allele in cell survival in vitro and in the clinical outcome of patients with advanced breast cancer.

  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20080101

• The central proline rich region of POB1/REPS2 plays a regulatory role in epidermal growth factor receptor endocytosis by binding to 14-3-3 and SH3 domain-containing proteins.

  BMC biochemistry 20080101

• Mapping natural polymorphisms of hepatitis C virus NS3/4A protease and antiviral resistance to inhibitors in worldwide isolates.

  Antiviral therapy 20080101

• [A comparative analysis of distribution of glyprolines administered by various routes].

  Bioorganicheskaia khimiia 20080101

• Investigating the mode of action of proline-rich antimicrobial peptides using a genetic approach: a tool to identify new bacterial targets amenable to the design of novel antibiotics.

  Methods in molecular biology (Clifton, N.J.) 20080101

• Pro370Leu MYOC gene mutation in a large Chinese family with juvenile-onset open angle glaucoma: correlation between genotype and phenotype.

  Molecular vision 20080101

• Mechanism of fast peptide recognition by SH3 domains.

  Angewandte Chemie (International ed. in English) 20080101

• NF-kappaB and AP-1 are key signaling pathways in the modulation of NAD(P)H:quinone oxidoreductase 1 gene by mercury, lead, and copper.

  Journal of biochemical and molecular toxicology 20080101

• Structural and spectroscopic elucidation of tetrapetide glycyl-(L)-prolyl-glycyl-glycine and its hydrogensquarate.

  Protein and peptide letters 20080101

• p53 codon 72 proline/arginine polymorphism and autoimmune thyroid diseases.

  Journal of clinical laboratory analysis 20080101

• [Interstrain differences in the content of excitatory and inhibitory amino acids in the brain of DBA/2J, Balb/c and C57BL/6 mice: characteristics of the effect of a dipeptide antipsychotic drug dilept].

  Eksperimental'naia i klinicheskaia farmakologiia 20080101

• Proline-catalyzed asymmetric formal alpha-alkylation of aldehydes via vinylogous iminium ion intermediates generated from arylsulfonyl indoles.

  Angewandte Chemie (International ed. in English) 20080101

• Noncovalent interactions between ([18]crown-6)-tetracarboxylic acid and amino acids: electrospray-ionization mass spectrometry investigation of the chiral-recognition processes.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• The human neonatal small intestine has the potential for arginine synthesis; developmental changes in the expression of arginine-synthesizing and -catabolizing enzymes.

  BMC developmental biology 20080101

• Proline-catalyzed highly enantioselective and anti-selective Mannich reaction of unactivated ketones: synthesis of chiral alpha-amino acids.

  Angewandte Chemie (International ed. in English) 20080101

• The effect of semax and the C-terminal peptide PGP on expression of growth factor genes and receptors in rats under conditions of experimental cerebral ischemia.

  Doklady. Biochemistry and biophysics 20080101

• Albumin induces interleukin-6 release from primary human proximal tubule epithelial cells.

  Journal of nephrology 20080101

• Association of mild and severely unstable alpha chain variants: the first observation of a compound heterozygote with Hb Setif [alpha94(G1)Asp-->Tyr (alpha2)] and Hb Agrinio [alpha29(B10)Leu-->Pro (alpha2)] in a Greek family.

  Hemoglobin 20080101

• TP53 gene expression, codon 72 polymorphism and human papillomavirus DNA associated with pterygium.

  Genetics and molecular research : GMR 20080101

• TP53 codon 72 polymorphism in adult soft tissue sarcomas.

  Genetics and molecular research : GMR 20080101

• Calnexin is not essential for mammalian rod opsin biogenesis.

  Molecular vision 20080101

• Molecular imaging of hypoxia-inducible factor 1 alpha and von Hippel-Lindau interaction in mice.

  Molecular imaging 20080101

• Future treatment options for HCV: double, triple, what is the optimal combination?

  Best practice & research. Clinical gastroenterology 20080101

• Cerebellopontine angle tumor in a patient with a maternally inherited SDHD gene mutation.

  The international tinnitus journal 20080101

• [Scaffolds based on collagen and chitosan for post-burn tissue engineering].

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20080101

• Effects of a nutrient mixture on infectious properties of the highly pathogenic strain of avian influenza virus A/H5N1.

  BioFactors (Oxford, England) 20080101

• The association of Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma gene with serum osteoprotegerin levels in healthy Korean women.

  Experimental & molecular medicine 20071231

• BINOL-amino acid conjugates as triggerable carriers of DNA-targeted potent photocytotoxic agents.

  Journal of medicinal chemistry 20071227

• Allosteric modulation of the dopamine receptor by conformationally constrained type VI beta-turn peptidomimetics of Pro-Leu-Gly-NH2.

  Journal of medicinal chemistry 20071227

• The active site of an algal prolyl 4-hydroxylase has a large structural plasticity.

  The Journal of biological chemistry 20071221

• Asymmetric organocatalytic direct aldol reactions of ketones with alpha-keto acids and their application to the synthesis of 2-hydroxy-gamma-butyrolactones.

  The Journal of organic chemistry 20071221

• Microwave-assisted organocatalytic anomerization of alpha-C-glycosylmethyl aldehydes and ketones.

  The Journal of organic chemistry 20071221

• Conformational analysis of L-prolines in water.

  The journal of physical chemistry. B 20071220

• The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals.

  Neuron 20071220

• Rare myelin protein zero sequence variant in late onset CMT1B.

  Journal of the neurological sciences 20071215

• Adult onset cerebral form of X-linked adrenoleukodystrophy with dementia of frontal lobe type with new L160P mutation in ABCD1 gene.

  Journal of the neurological sciences 20071215

• Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts.

  International journal of cancer 20071215

• Intrathecal injection of glutamate receptor antagonists/agonist selectively attenuated rat pain-related behaviors induced by the venom of scorpion Buthus martensi Karsch.

  Toxicon : official journal of the International Society on Toxinology 20071215

• Proline promotes decrease in glutamate uptake in slices of cerebral cortex and hippocampus of rats.

  Life sciences 20071214

• Clarification of the role of water in proline-mediated aldol reactions.

  Journal of the American Chemical Society 20071212

• A comparative study of different glycosylation methods for the synthesis of D-mannopyranosides of Nalpha-fluorenylmethoxycarbonyl-trans-4-hydroxy-L-proline allyl ester.

  Carbohydrate research 20071210

• Backbone dynamics in an intramolecular prolylpeptide-SH3 complex from the diphtheria toxin repressor, DtxR.

  Journal of molecular biology 20071207

• Magnetic nanoparticle-supported proline as a recyclable and recoverable ligand for the CuI catalyzed arylation of nitrogen nucleophiles.

  Chemical communications (Cambridge, England) 20071207

• Stimulatory effect of N-(1-deoxy-beta-d-fructopyranos-1-yl)-l-proline on antibody production in mice.

  International immunopharmacology 20071205

• Deletion of v7-3 (SLC6A15) transporter allows assessment of its roles in synaptosomal proline uptake, leucine uptake and behaviors.

  Brain research 20071205

• A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse.

  Proceedings of the National Academy of Sciences of the United States of America 20071204

• Multigram solution-phase synthesis of three diastereomeric tripeptidic second-generation dendrons based on (2S,4S)-, (2S,4R)-, and (2R,4S)-4-aminoprolines.

  Chemistry, an Asian journal 20071203

• Glycosaminoglycan, collagen, and glycosidase changes in human osteoblasts treated with interleukin 1, and osteodystrophy.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20071201

• Fast Fmoc synthesis of hAmylin1-37 with pseudoproline assisted on-resin disulfide formation.

  Journal of peptide science : an official publication of the European Peptide Society 20071201

• Enhancement of thermal stability and inhibition of protein aggregation by osmolytic effect of hydroxyproline.

  Biopolymers 20071201

• The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obesity-related traits in the Diabetes Prevention Program.

  Diabetologia 20071201

• Molecular modeling of the prekallikrein structure provides insights into high-molecular-weight kininogen binding and zymogen activation.

  Journal of thrombosis and haemostasis : JTH 20071201

• Aggregate formation of mutant protein kinase C gamma found in spinocerebellar ataxia type 14 impairs ubiquitin-proteasome system and induces endoplasmic reticulum stress.

  The European journal of neuroscience 20071201

• Disruption of dopamine homeostasis underlies selective neurodegeneration mediated by alpha-synuclein.

  The European journal of neuroscience 20071201

• Simultaneous determination of 3-nitrotyrosine, tyrosine, hydroxyproline and proline in exhaled breath condensate by hydrophilic interaction liquid chromatography/electrospray ionization tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071201

• Site-specific effects of tau phosphorylation on its microtubule assembly activity and self-aggregation.

  The European journal of neuroscience 20071201

• Effects of orange juice and proline betaine on glycine betaine and homocysteine in healthy male subjects.

  European journal of nutrition 20071201

• Drosophila ASPP regulates C-terminal Src kinase activity.

  Developmental cell 20071201

• Alterations in lipid peroxidation, electrolyte leakage, and proline metabolism in Catharanthus roseus under treatment with triadimefon, a systemic fungicide.

  Comptes rendus biologies 20071201

• Small-molecule H-bond donors in asymmetric catalysis.

  Chemical reviews 20071201

• Structural investigation of endomorphins by experimental and theoretical methods: hunting for the bioactive conformation.

  Chemistry & biodiversity 20071201

• [Inhibition of NF-kappa B activity enhanced apoptosis induced by matrine in hepatocellular carcinoma cells].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20071201

• Molecular vibrations and normal modes in L-prolyl-glycyl-glycine using Wilson GF matrix method.

  Indian journal of biochemistry & biophysics 20071201

• [Exogenous nitric oxide accelerates soluble sugar, proline and secondary metabolite synthesis in Ginkgo biloba under drought stress].

  Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20071201

• Prostaglandin E2 activates HPK1 kinase activity via a PKA-dependent pathway.

  The Journal of biological chemistry 20071130

• Stimulation by glutamine and proline of HGF production in hepatic stellate cells.

  Biochemical and biophysical research communications 20071130

• Miniature protein ligands for EVH1 domains: interplay between affinity, specificity, and cell motility.

  Biochemistry 20071127

• Insight into the binding properties of MEKK3 PB1 to MEK5 PB1 from its solution structure.

  Biochemistry 20071127

• Asymmetric aldol reaction catalyzed by a heterogenized proline on a mesoporous support. The role of the nature of solvents.

  The Journal of organic chemistry 20071123

• Molecular building kit of fused-proline-derived peptide mimetics allowing specific adjustment of the dihedral Psi angle.

  The Journal of organic chemistry 20071123

• Facile access to polysubstituted indoles via a cascade Cu-catalyzed arylation-condensation process.

  The Journal of organic chemistry 20071123

• Lewis acid- and organocatalyst-cocatalyzed multicomponent reactions of 2-alkynylbenzaldehydes, amines, and ketones.

  Organic letters 20071122

• Nuclear factor-kappaB p65 facilitates longitudinal bone growth by inducing growth plate chondrocyte proliferation and differentiation and by preventing apoptosis.

  The Journal of biological chemistry 20071116

• Differential effects of hexaconazole and paclobutrazol on biomass, electrolyte leakage, lipid peroxidation and antioxidant potential of Daucus carota L.

  Colloids and surfaces. B, Biointerfaces 20071115

• Structure and evolution of RIM-BP genes: identification of a novel family member.

  Gene 20071115

• Mapping of a region of Ebola virus VP40 that is important in the production of virus-like particles.

  The Journal of infectious diseases 20071115

• Quantifying the intrinsic effects of two point mutation models of pro-pro-pro triamino acid diamide. A first-principle computational study.

  The journal of physical chemistry. B 20071115

• Sodium and proline accumulation as osmoregulators in tolerance of sugar beet genotypes to salinity.

  Pakistan journal of biological sciences : PJBS 20071115

• Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase.

  The Journal of biological chemistry 20071109

• Structural characterization of a new binding motif and a novel binding mode in group 2 WW domains.

  Journal of molecular biology 20071109

• Exogenous proline and glycinebetaine increase NaCl-induced ascorbate-glutathione cycle enzyme activities, and proline improves salt tolerance more than glycinebetaine in tobacco Bright Yellow-2 suspension-cultured cells.

  Journal of plant physiology 20071101

• Arg72Pro p53 polymorphism in Italian women: no association with endometriosis.

  Fertility and sterility 20071101

• An analysis of peroxisome proliferator-activated receptor gamma (PPAR-gamma 2) Pro12Ala polymorphism distribution and prevalence of type 2 diabetes mellitus (T2DM) in world populations in relation to dietary habits.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20071101

• Proline prodrug of melphalan, prophalan-L, demonstrates high therapeutic index in a murine melanoma model.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20071101

• Biochemical characterization, homology modeling and docking studies of ornithine delta-aminotransferase--an important enzyme in proline biosynthesis of plants.

  Journal of molecular graphics & modelling 20071101

• Sprouty2 binds Grb2 at two different proline-rich regions, and the mechanism of ERK inhibition is independent of this interaction.

  Cellular signalling 20071101

• Effect of the Ala12 allele in the PPARgamma-2 gene on the relationship between birth weight and body composition in adolescents: the AVENA study.

  Pediatric research 20071101

• Small molecule inhibitors of integrin alpha2beta1.

  Journal of medicinal chemistry 20071101

• Investigation of the amino acids glycine, proline, and methionine by photoemission spectroscopy.

  The journal of physical chemistry. A 20071101

• NaCl as a physiological modulator of proline metabolism and antioxidant potential in Phyllanthus amarus.

  Comptes rendus biologies 20071101

• [Vitamin K and bone quality].

  Clinical calcium 20071101

• Distribution of neuropeptide Y Leu7Pro polymorphism in patients with type 1 diabetes and diabetic nephropathy among Swedish and American populations.

  European journal of endocrinology 20071101

• Role of Rel A and IkappaB of nuclear factor kappaB in the release of interleukin-8 by cyclic mechanical strain in human alveolar type II epithelial cells A549.

  Respirology (Carlton, Vic.) 20071101

• Anti-parallel membrane topology of a homo-dimeric multidrug transporter, EmrE.

  Journal of biochemistry 20071101

• Extracellular matrix-mediated control of aortic smooth muscle cell growth and migration by a combination of ascorbic acid, lysine, proline, and catechins.

  Journal of cardiovascular pharmacology 20071101

• Functional analysis of genes encoding putative oxidoreductases in Aspergillus oryzae, which are similar to fungal fructosyl-amino acid oxidase.

  Journal of bioscience and bioengineering 20071101

• [Experimental studies on compound Duzhong Jiangya prescription by semi-bionic extraction].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071101

• Synthetic ligands discovered by in vitro selection.

  Journal of the American Chemical Society 20071031

• Differential colchicine-binding across eukaryotic families: the role of highly conserved Pro268beta and Ala248beta residues in animal tubulin.

  FEBS letters 20071030

• Selective defluorination approach to N-Cbz-3,3-difluoro-2-difluoromethylenepyrrolidine and its application to 3,3-difluoroproline dipeptide synthesis.

  The Journal of organic chemistry 20071026

• Organocatalytic asymmetric robinson annulation of alpha,beta-unsaturated aldehydes: applications to the total synthesis of (+)-palitantin.

  The Journal of organic chemistry 20071026

• Pockets of short-range transient order and restricted topological heterogeneity in the guanidine-denatured state ensemble of GED of dynamin.

  Biochemistry 20071023

• Spoilt for choice: assessing phase behavior models for the evolution of homochirality.

  Chemical communications (Cambridge, England) 20071021

• A conserved proline residue in the leucine zipper region of AtbZIP34 and AtbZIP61 in Arabidopsis thaliana interferes with the formation of homodimer.

  Biochemical and biophysical research communications 20071019

• Time dependence of cyclic tensile strain on collagen production in tendon fascicles.

  Biochemical and biophysical research communications 20071019

• Restricted backbone conformational and motional flexibilities of loops containing peptidyl-proline bonds dominate the enzyme activity of staphylococcal nuclease.

  Biochemistry 20071016

• Water deficit stress mitigation by calcium chloride in Catharanthus roseus: effects on oxidative stress, proline metabolism and indole alkaloid accumulation.

  Colloids and surfaces. B, Biointerfaces 20071015

• Human Kid is degraded by the APC/C(Cdh1) but not by the APC/C(Cdc20).

  Cell cycle (Georgetown, Tex.) 20071015

• Cloning and activation of the bullfrog apelin receptor: Gi/o coupling and high affinity for [Pro1]apelin-13.

  Molecular and cellular endocrinology 20071015

• Proline homozygosity in codon 72 of TP53 is a factor of susceptibility to nasopharyngeal carcinoma in Tunisia.

  Cancer genetics and cytogenetics 20071015

• Increasing protein conformational stability by optimizing beta-turn sequence.

  Journal of molecular biology 20071012

• In vitro effect of PPAR-gamma2 Pro12Ala polymorphism on the deposition of Alzheimer's amyloid-beta peptides.

  Brain research 20071010

• Observation of immobilized water molecules around hydrophobic groups.

  Physical review letters 20071005

• Effects of bioactive peptides isoleucine-proline-proline (IPP), valine-proline-proline (VPP) and leucine-lysine-proline (LKP) on gene expression of osteoblasts differentiated from human mesenchymal stem cells.

  The British journal of nutrition 20071001

• Growth, biochemical modifications and proline metabolism in Helianthus annuus L. as induced by drought stress.

  Colloids and surfaces. B, Biointerfaces 20071001

• Enzyme replacement therapy in 12 patients with MPS I-H/S with homozygous p.Leu490Pro mutation.

  Journal of inherited metabolic disease 20071001

• Lung alveolar proteomics of bronchoalveolar lavage from a pulmonary alveolar proteinosis patient using high-resolution FTICR mass spectrometry.

  Analytical and bioanalytical chemistry 20071001

• Stress-induced synthesis of proline confers tolerance to water deficit in transgenic wheat.

  Journal of plant physiology 20071001

• Mild ocular myopathy associated with a novel mutation in mitochondrial twinkle helicase.

  Neuromuscular disorders : NMD 20071001

• Proline-rich polypeptides in Alzheimer's disease and neurodegenerative disorders -- therapeutic potential or a mirage?

  Progress in neuro-psychopharmacology & biological psychiatry 20071001

• The role of Phe181 in the hexamerization of Helicobacter pylori quinolinate phosphoribosyltransferase.

  The protein journal 20071001

• Predisposition to HPV16/18-related cervical cancer because of proline homozygosity at codon 72 of p53 among Indian women is influenced by HLA-B*07 and homozygosity of HLA-DQB1*03.

  Tissue antigens 20071001

• On Cu(II)-Cu(II) distance measurements using pulsed electron electron double resonance.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20071001

• Inhibition of corneal neovascularization with a nutrient mixture containing lysine, proline, ascorbic acid, and green tea extract.

  Archives of medical research 20071001

• Prolyl cis-trans isomerization as a molecular timer.

  Nature chemical biology 20071001

• Identification of amino acids involved in the Flo11p-mediated adhesion of Saccharomyces cerevisiae to a polystyrene surface using phage display with competitive elution.

  Journal of applied microbiology 20071001

• Morphological and physiological characteristics of rapeseed plants regenerated in vitro from thin cell layers in the presence of zinc.

  Comptes rendus biologies 20071001

• Multienzyme assembly of a p53 transcription complex.

  Nature structural & molecular biology 20071001

• Frequency of TP53 mutations in relation to Arg72Pro genotypes in non small cell lung cancer.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20071001

• Amino acid substitutions at proline 220 of beta-tubulin confer resistance to paclitaxel and colcemid.

  Molecular cancer therapeutics 20071001

• Charcot-Marie-Tooth disease type 4C4 caused by a novel Pro153Leu substitution in the GDAP1 gene.

  Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology 20071001

• Changes in hemostatic parameters after intranasal administration of peptide Pro-Gly-Pro.

  Bulletin of experimental biology and medicine 20071001

• Effects of glycosylation of (2S,4R)-4-hydroxyproline on the conformation, kinetics, and thermodynamics of prolyl amide isomerization.

  Journal of the American Chemical Society 20070926

• Ruthenium catalyzed decarbonylative arylation at sp3 carbon centers in pyrrolidine and piperidine heterocycles.

  Journal of the American Chemical Society 20070926

• Hsp70-GlcNAc-binding activity is released by stress, proteasome inhibition, and protein misfolding.

  Biochemical and biophysical research communications 20070921

• Entrapped energy in chiral solutions: quantification and information capacity.

  The journal of physical chemistry. B 20070920

• The mapped pattern of kainate on blood pressure responses is similar to that of L-proline in the ventrolateral medulla of the rat.

  Neuroscience letters 20070920

• Specificity of translation for N-alkyl amino acids.

  Journal of the American Chemical Society 20070919

• Enhanced stability of cis Pro-Pro peptide bond in Pro-Pro-Phe sequence motif.

  FEBS letters 20070918

• Pore-size tunable mesoporous zirconium organophosphonates with chiral L-proline for enzyme adsorption.

  Inorganic chemistry 20070917

• 2R, 4R-APDC decreases cell proliferation in the dentate gyrus of adult rats: the effect of 2R, 4R-APDC on cell proliferation.

  Neuroreport 20070917

• Late-onset Charcot-Marie-Tooth type 2 disease with hearing impairment associated with a novel Pro105Thr mutation in the MPZ gene.

  American journal of medical genetics. Part A 20070915

• N-(2-Nitrophenyl)proline: an intramolecular hydrogen bond forming reagent for the determination of the absolute configuration of primary amines.

  Organic letters 20070913

• MYOC gene mutations in Spanish patients with autosomal dominant primary open-angle glaucoma: a founder effect in southeast Spain.

  Molecular vision 20070913

• Structure of the cytoplasmic domain of erythrocyte band 3 hereditary spherocytosis variant P327R: band 3 Tuscaloosa.

  Biochemistry 20070911

• Study of antibodies to PMP22, IL-6 and TNF-alpha concentrations in serum in a CMTX1 family.

  Neuroscience letters 20070907

• Interpreting sequences from mastodon and T. rex.

  Science (New York, N.Y.) 20070907

• Puckering transition of proline residue in water.

  The journal of physical chemistry. B 20070906

• Leu7Pro polymorphism of PreproNPY associated with an increased risk for type II diabetes in middle-aged subjects.

  European journal of clinical nutrition 20070901

• Potential contribution of nuclear factor-kappaB to cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070901

• Characterization of compatible solute transporter multiplicity in Corynebacterium glutamicum.

  Applied microbiology and biotechnology 20070901

• Rubidium chloride tolerant callus cultures of rice (Oryza sativa L.) accumulate more potassium and cross tolerate to other salts.

  Plant cell reports 20070901

• Arabidopsis DREB1A/CBF3 bestowed transgenic tall fescue increased tolerance to drought stress.

  Plant cell reports 20070901

• Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library.

  The Journal of pharmacology and experimental therapeutics 20070901

• A mutation in human VAP-B--MSP domain, present in ALS patients, affects the interaction with other cellular proteins.

  Protein expression and purification 20070901

• Overexpression of OsCOIN, a putative cold inducible zinc finger protein, increased tolerance to chilling, salt and drought, and enhanced proline level in rice.

  Planta 20070901

• A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) through 15-deoxy-Delta 12, 14 prostaglandin J2 production.

  Blood 20070901

• Association of Trp53 polymorphic variants at codon 72 with nonsyndromic mental retardation.

  Neuroscience research 20070901

• Plasma concentrations of arginine and related amino acids following traumatic brain injury: Proline as a promising biomarker of brain damage severity.

  Nitric oxide : biology and chemistry 20070901

• Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer.

  Carcinogenesis 20070901

• Fesselin is a natively unfolded protein.

  Journal of proteome research 20070901

• Detection of secondary thalamic degeneration after cortical infarction using cis-4-18F-fluoro-D-proline.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20070901

• Hereditary inclusion body myopathy with a novel mutation in the GNE gene associated with proximal leg weakness and necrotizing myopathy.

  European journal of neurology 20070901

• Calcium chloride effects on salinity-induced oxidative stress, proline metabolism and indole alkaloid accumulation in Catharanthus roseus.

  Comptes rendus biologies 20070901

• An experimental correction for arginine-to-proline conversion artifacts in SILAC-based quantitative proteomics.

  Nature methods 20070901

• Capturing candidate drought tolerance traits in two native Andean potato clones by transcription profiling of field grown plants under water stress.

  Plant physiology and biochemistry : PPB 20070901

• [Study on myxomycetes as a new source of bioactive natural products].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070901

• An unusual presentation of macular corneal dystrophy associated with uniparental isodisomy and a novel Leu173Pro mutation.

  Ophthalmic genetics 20070901

• [Effects of rice-duck farming system on physiological characters of rice].

  Ying yong sheng tai xue bao = The journal of applied ecology 20070901

• Gene transcription in the leaves of rice undergoing salt-induced morphological changes (Oryza sativa L.).

  Molecules and cells 20070831

• Role of non-phosphorylated activation loop residues in determining ERK2 dephosphorylation, activity, and subcellular localization.

  The Journal of biological chemistry 20070824

• Functional organization of presynaptic metabotropic glutamate receptors in vagal brainstem circuits.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070822

• Dark rearing rescues P23H rhodopsin-induced retinal degeneration in a transgenic Xenopus laevis model of retinitis pigmentosa: a chromophore-dependent mechanism characterized by production of N-terminally truncated mutant rhodopsin.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070822

• Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070822

• Reversible and irreversible coiled coils in the stalk domain of ncd motor protein.

  Biochemistry 20070821

• Characterization and alkane oxidation activity of a diastereopure seven-coordinate iron(III) alkylperoxo complex.

  Dalton transactions (Cambridge, England : 2003) 20070821

• V-PROLI/NO, a prodrug of the nitric oxide donor, PROLI/NO.

  Organic letters 20070816

• An importin alpha/beta-recognized bipartite nuclear localization signal mediates targeting of the human herpes simplex virus type 1 DNA polymerase catalytic subunit pUL30 to the nucleus.

  Biochemistry 20070814

• Comparison of L-monosodium glutamate and L-amino acid taste in rats.

  Neuroscience 20070810

• A (-)-sparteine-directed highly enantioselective synthesis of boroproline. Solid- and solution-state structure and properties.

  The Journal of organic chemistry 20070803

• A memory of chirality approach to the stereoselective synthesis of 4-hydroxy-alpha-methylprolines.

  Organic letters 20070802

• Novel features in a patient homozygous for the L347P mutation in the PINK1 gene.

  Parkinsonism & related disorders 20070801

• Lack of evidence that p53 Arg72Pro influences lung cancer prognosis: an analysis of survival in 619 female patients.

  Lung cancer (Amsterdam, Netherlands) 20070801

• Syndapin I and endophilin I bind overlapping proline-rich regions of dynamin I: role in synaptic vesicle endocytosis.

  Journal of neurochemistry 20070801

• Role of Asn(2) and Glu(7) residues in the oxidative folding and on the conformation of the N-terminal loop of apamin.

  Biopolymers 20070801

• Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.

  Drug metabolism and disposition: the biological fate of chemicals 20070801

• Differential inhibition of CYP17A1 and CYP21A2 activities by the P450 oxidoreductase mutant A287P.

  Molecular endocrinology (Baltimore, Md.) 20070801

• Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia.

  International immunopharmacology 20070801

• Leaf water relations and net gas exchange responses of salinized Carrizo citrange seedlings during drought stress and recovery.

  Annals of botany 20070801

• CEC enantioseparations on chiral monolithic columns: a study of the stereoselective degradation of (R/S)-dichlorprop [2-(2,4-dichlorophenoxy)propionic acid] in soil.

  Electrophoresis 20070801

• Enhanced preference for pi-bond containing substrates is correlated to Pro110 in the substrate-binding tunnel of Escherichia coli thioesterase I/protease I/lysophospholipase L(1).

  Biochimica et biophysica acta 20070801

• First detection of the melanoma-predisposing proline-48-threonine mutation of p16 in Hungarians: was there a common founder either in Italy or in Hungary?

  Melanoma research 20070801

• Accurate charge density of the tripeptide Ala-Pro-Ala with the maximum entropy method (MEM): influence of data resolution.

  Acta crystallographica. Section B, Structural science 20070801

• Alpha-ketoglutarate stimulates procollagen production in cultured human dermal fibroblasts, and decreases UVB-induced wrinkle formation following topical application on the dorsal skin of hairless mice.

  Biological & pharmaceutical bulletin 20070801

• Zn-proline catalyzed selective synthesis of 1,2-disubstituted benzimidazoles in water.

  Chemical & pharmaceutical bulletin 20070801

• Prevention of amyloid-like aggregation as a driving force of protein evolution.

  EMBO reports 20070801

• Siderophores in fluorescent pseudomonads: new tricks from an old dog.

  Future microbiology 20070801

• [Effects of high temperature stress on root vitality and leaf biochemical indexes in different populations of Pinellia ternate].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801

• Histomorphological characteristics of accelerated healing of acetate ulcers under the effect of glyprolines.

  Bulletin of experimental biology and medicine 20070801

• Studies of the role of ubiquitination in the interaction of ubiquilin with the loop and carboxyl terminal regions of presenilin-2.

  Biochemistry 20070731

• Effects of osmolytes on RNA secondary and tertiary structure stabilities and RNA-Mg2+ interactions.

  Journal of molecular biology 20070727

• Interaction of thrombin with PAR1 and PAR4 at the thrombin cleavage site.

  Biochemistry 20070724

• Pre- and post-initiation chemoprevention activity of 2-alkyl/aryl selenazolidine-4(R)-carboxylic acids against tobacco-derived nitrosamine (NNK)-induced lung tumors in the A/J mouse.

  Chemico-biological interactions 20070720

• Mesophile versus thermophile: insights into the structural mechanisms of kinetic stability.

  Journal of molecular biology 20070720

• New access to indolizidine and pyrrolizidine alkaloids from an enantiopure proline: total syntheses of (-)-lentiginosine and (1R,2R,7aR)-dihydroxypyrrolizidine.

  The Journal of organic chemistry 20070720

• Structure of aqueous proline via parallel tempering molecular dynamics and neutron diffraction.

  The journal of physical chemistry. B 20070719

• Chiral separation of selected proline derivatives using a polysaccharide type stationary phase by high-performance liquid chromatography.

  Journal of chromatography. A 20070713

• Prediction of molar extinction coefficients of proteins and peptides using UV absorption of the constituent amino acids at 214 nm to enable quantitative reverse phase high-performance liquid chromatography-mass spectrometry analysis.

  Journal of agricultural and food chemistry 20070711

• The additive effect of p53 Arg72Pro and RNASEL Arg462Gln genotypes on age of disease onset in Lynch syndrome patients with pathogenic germline mutations in MSH2 or MLH1.

  Cancer letters 20070708

• Inverse-electron-demand hetero-Diels-Alder reaction of beta,gamma-unsaturated alpha-ketophosphonates catalyzed by prolinal dithioacetals.

  Organic letters 20070705

• Crystal structure of N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-proline-an Amadori compound.

  Carbohydrate research 20070702

• The proline permease of Aspergillus nidulans: functional replacement of the native cysteine residues and properties of a cysteine-less transporter.

  Fungal genetics and biology : FG & B 20070701

• Proline prodrug of melphalan targeted to prolidase, a prodrug activating enzyme overexpressed in melanoma.

  Pharmaceutical research 20070701

• Functional analysis of RalGPS2, a murine guanine nucleotide exchange factor for RalA GTPase.

  Experimental cell research 20070701

• A reassessment of the function of the so-called compatible solutes in the halophytic plumbaginaceae Limonium latifolium.

  Plant physiology 20070701

• Agonist-dependent consequences of proline to alanine substitution in the transmembrane helices of the calcitonin receptor.

  British journal of pharmacology 20070701

• Prolidase isoenzymes in the rat: their organ distribution, developmental change and specific inhibitors.

  Pediatric research 20070701

• Expression of beta-keratin mRNAs and proline uptake in epidermal cells of growing scales and pad lamellae of gecko lizards.

  Journal of anatomy 20070701

• The role of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma in diabetes risk.

  Current opinion in clinical nutrition and metabolic care 20070701

• Beta-keratins of differentiating epidermis of snake comprise glycine-proline-serine-rich proteins with an avian-like gene organization.

  Developmental dynamics : an official publication of the American Association of Anatomists 20070701

• [Biochemistry and structural biology of microbial enzymes and their medical applications].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070701

• Synthesis and DNA binding/cleavage of mononuclear copper(II) phenanthroline/bipyridine proline complexes.

  Chemistry & biodiversity 20070701

• [Synthesis and spectral characterization of novel chiral macrocyclic dioxopolyamines].

  Guang pu xue yu guang pu fen xi = Guang pu 20070701

• Peptide correction of disorders in rat mesenteric microcirculatory system during inflammation.

  Bulletin of experimental biology and medicine 20070701

• Effects of copper on chlorophyll, proline, protein and abscisic acid level of sunflower (Helianthus annuus L.) seedlings.

  Journal of environmental biology 20070701

• Linear solvation energy correlation of the solvatochromic response of amino acid functionalized chromophores.

  The journal of physical chemistry. B 20070628

• Dissecting the proline effect: dissociations of proline radicals formed by electron transfer to protonated Pro-Gly and Gly-Pro dipeptides in the gas phase.

  Journal of the American Chemical Society 20070627

• Stress-responsive Gln3 localization in Saccharomyces cerevisiae is separable from and can overwhelm nitrogen source regulation.

  The Journal of biological chemistry 20070622

• Tuning of the prolyl trans/cis-amide rotamer population by use of C-glucosylproline hybrids.

  The Journal of organic chemistry 20070622

• Unique side chain conformation of a Leu residue in a triple-helical structure.

  Biopolymers 20070615

• Artificially evolved Synechococcus PCC6301 Rubisco variants exhibit improvements in folding and catalytic efficiency.

  The Biochemical journal 20070615

• Structural and functional basis of amino acid specificity in the invertebrate cotransporter KAAT1.

  The Journal of physiology 20070615

• Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression.

  The Journal of biological chemistry 20070615

• A novel mutation in human ether-a-go-go-related gene, alanine to proline at position 490, found in a large family with autosomal dominant long QT syndrome.

  The American journal of cardiology 20070615

• Salt pretreatment enhance salt tolerance in Zea mays L. seedlings.

  Pakistan journal of biological sciences : PJBS 20070615

• Anharmonic effects in IR, Raman, and Raman optical activity spectra of alanine and proline zwitterions.

  The Journal of chemical physics 20070614

• A conserved cis-proline precludes metal binding by the active site thiolates in members of the thioredoxin family of proteins.

  Biochemistry 20070612

• Effects of a mutation in the TM2-TM3 linker region of the glycine receptor alpha1 subunit on gating and allosteric modulation.

  Brain research 20070604

• Uniconazole-induced tolerance of soybean to water deficit stress in relation to changes in photosynthesis, hormones and antioxidant system.

  Journal of plant physiology 20070601

• Glutamine synthetase and glutamate dehydrogenase contribute differentially to proline accumulation in leaves of wheat (Triticum aestivum) seedlings exposed to different salinity.

  Journal of plant physiology 20070601

• Intercellular trafficking and cytotoxicity of recombinant HSV-1 thymidine kinase fused with HSV-2 US11 RXP repeat peptide.

  Virus genes 20070601

• A novel mouse protein differentially regulated by androgens in the submandibular and lacrimal glands.

  Archives of oral biology 20070601

• Integrin beta3 Leu33Pro polymorphism increases BRCA1-associated ovarian cancer risk.

  Journal of medical genetics 20070601

• Ultra-performance liquid chromatography/tandem mass spectrometric determination of diastereomers of SCH 503034 in monkey plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601

• A proline repeat domain in the Notch co-activator MAML1 is important for the p300-mediated acetylation of MAML1.

  The Biochemical journal 20070601

• Cleavage after residue Ala352 in the C-terminal extension is an early step in the maturation of the D1 subunit of Photosystem II in Synechocystis PCC 6803.

  Biochimica et biophysica acta 20070601

• Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells.

  American journal of physiology. Lung cellular and molecular physiology 20070601

• Amino acid and codon use: in two influenza viruses and three hosts.

  Medecine et maladies infectieuses 20070601

• Leisure-time physical activity is associated with the metabolic syndrome in type 1 diabetes: effect of the PPARgamma Pro12Ala polymorphism: the FinnDiane Study.

  Diabetes care 20070601

• YC-1 attenuates LPS-induced proinflammatory responses and activation of nuclear factor-kappaB in microglia.

  British journal of pharmacology 20070601

• The major secreted cathepsin L1 protease of the liver fluke, Fasciola hepatica: a Leu-12 to Pro-12 replacement in the nonconserved C-terminal region of the prosegment prevents complete enzyme autoactivation and allows definition of the molecular events in prosegment removal.

  The Journal of biological chemistry 20070601

• The Pro12Ala polymorphism in PPARG2 increases the effectiveness of primary prevention of cardiovascular disease by a lifestyle intervention.

  Diabetologia 20070601

• Responses of photosynthesis, chlorophyll fluorescence and ROS-scavenging systems to salt stress during seedling and reproductive stages in rice.

  Annals of botany 20070601

• Multiple fungal enzymes possess cysteine synthase activity in vitro.

  Research in microbiology 20070601

• Effect of selected Ser/Ala and Xaa/Pro mutations on the stability and catalytic properties of a cold adapted subtilisin-like serine proteinase.

  Biochimica et biophysica acta 20070601

• Alpha-D-mannopyranosyl-(1-->2)-alpha-D-glucopyranosyl-(1-->2)-glycerate in the thermophilic bacterium Petrotoga miotherma--structure, cellular content and function.

  The FEBS journal 20070601

• Expression of Bacillus subtilis proBA genes and reduction of feedback inhibition of proline synthesis increases proline production and confers osmotolerance in transgenic Arabidopsis.

  Journal of biochemistry and molecular biology 20070531

• Development of an electrolytic system for non-Kolbe electrolysis based on the acid-base reaction between carboxylic acids as a substrate and solid-supported bases.

  Journal of the American Chemical Society 20070530

• Proline induces alterations on nucleotide hydrolysis in synaptosomes from cerebral cortex of rats.

  Brain research 20070529

• Actin binding and proline rich motifs of CR16 play redundant role in growth of vrp1Delta cells.

  Biochemical and biophysical research communications 20070525

• SmI(2)-promoted radical addition reactions with N-(2-Indolylacyl)oxazolidinones: synthesis of bisindole compounds.

  The Journal of organic chemistry 20070525

• Force-induced prolyl cis-trans isomerization in elastin-like polypeptides.

  Journal of the American Chemical Society 20070523

• Insertion of a chaperone domain converts FKBP12 into a powerful catalyst of protein folding.

  Journal of molecular biology 20070518

• A single amino acid in the second transmembrane domain of GABA rho receptors regulates channel conductance.

  Neuroscience letters 20070517

• Conformational preferences and cis-trans isomerization of azaproline residue.

  The journal of physical chemistry. B 20070517

• Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization.

  Journal of medicinal chemistry 20070517

• Conformations of proline analogues having double bonds in the ring.

  The journal of physical chemistry. B 20070517

• The polymorphism P315L of human toll-like receptor 1 impairs innate immune sensing of microbial cell wall components.

  Journal of immunology (Baltimore, Md. : 1950) 20070515

• Structure and kinetics of monofunctional proline dehydrogenase from Thermus thermophilus.

  The Journal of biological chemistry 20070511

• Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains.

  The Journal of biological chemistry 20070511

• Systematic Analysis of proteoglycan modification sites in Caenorhabditis elegans by scanning mutagenesis.

  The Journal of biological chemistry 20070511

• Development of NaCl-tolerant line in Chrysanthemum morifolium Ramat. through shoot organogenesis of selected callus line.

  Journal of biotechnology 20070510

• Highly enantioselective alpha-aminoxylation of aldehydes and ketones with a polymer-supported organocatalyst.

  Organic letters 20070510

• Practical synthesis of enantiomerically pure beta2-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes.

  Journal of the American Chemical Society 20070509

• Double mutant P96S/S120G of Nm23-H1 abrogates its NDPK activity and motility-suppressive ability.

  Biochemical and biophysical research communications 20070504

• The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin.

  Journal of molecular biology 20070504

• Structure and hydration of L-proline in aqueous solutions.

  The journal of physical chemistry. B 20070503

• Exogenous proline mitigates the detrimental effects of salt stress more than exogenous betaine by increasing antioxidant enzyme activities.

  Journal of plant physiology 20070501

• Effects of lead contamination on soil enzymatic activities, microbial biomass, and rice physiological indices in soil-lead-rice (Oryza sativa L.) system.

  Ecotoxicology and environmental safety 20070501

• Effect of vitamin C and folic acid on seed vigour response and phenolic-linked antioxidant activity.

  Bioresource technology 20070501

• The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites.

  Journal of molecular medicine (Berlin, Germany) 20070501

• Pro12Ala polymorphism of the PPARgamma2 locus modulates the relationship between energy intake and body weight in type 2 diabetic patients.

  Diabetes care 20070501

• The N-terminal conformation of Bax regulates cell commitment to apoptosis.

  Cell death and differentiation 20070501

• Dipeptidyl peptidase 8/9-like activity in human leukocytes.

  Journal of leukocyte biology 20070501

• Relaxin-induced matrix metalloproteinase-9 expression is associated with activation of the NF-kappaB pathway in human THP-1 cells.

  Journal of leukocyte biology 20070501

• Loss of caveolin-3 induced by the dystrophy-associated P104L mutation impairs L-type calcium channel function in mouse skeletal muscle cells.

  The Journal of physiology 20070501

• Altered ABA, proline and hydrogen peroxide in an Arabidopsis glutamate:glyoxylate aminotransferase mutant.

  Plant molecular biology 20070501

• Calcium signaling via phospholipase C is essential for proline accumulation upon ionic but not nonionic hyperosmotic stresses in Arabidopsis.

  Plant physiology 20070501

• Mapping of the epitope of monoclonal antibody 2B4 to the proline-rich region of human Huntingtin, a region critical for aggregation and toxicity.

  Biotechnology journal 20070501

• N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis.

  Nature cell biology 20070501

• The epidermis of scales in gecko lizards contains multiple forms of beta-keratins including basic glycine-proline-serine-rich proteins.

  Journal of proteome research 20070501

• Hydrogen-bonding features in the 1:2 adduct of 4-aminobenzoic acid and L-proline.

  Acta crystallographica. Section C, Crystal structure communications 20070501

• Impact of the Leu7Pro polymorphism of preproNPY on diurnal NPY and hormone secretion in type 2 diabetes.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20070501

• Hb Evora [alpha 2-35, Ser-->Pro], a novel hemoglobin variant associated with an alpha-thalassemia phenotype.

  Haematologica 20070501

• [Molecular mechanisms of drought tolerance and signal transduction in plants].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20070501

• [A novel mutation in infant hypophophatasia: a case report].

  La Tunisie medicale 20070501

• Effects of semax and its Pro-Gly-Pro fragment on calcium homeostasis of neurons and their survival under conditions of glutamate toxicity.

  Bulletin of experimental biology and medicine 20070501

• Group II metabotropic glutamate receptors reduce excitatory but not inhibitory neurotransmission in rat barrel cortex in vivo.

  Neuroscience 20070425

• Infrared multiple photon dissociation spectra of proline and glycine proton-bound homodimers. Evidence for zwitterionic structure.

  Journal of the American Chemical Society 20070425

• The p53 codon 72 proline allele is endowed with enhanced cell-death inducing potential in cancer cells exposed to hypoxia.

  British journal of cancer 20070423

• Regulation of a transcript encoding the proline-rich membrane anchor of globular muscle acetylcholinesterase. The suppressive roles of myogenesis and innervating nerves.

  The Journal of biological chemistry 20070420

• A proline to glycine mutation in the Lck SH3-domain affects conformational sampling and increases ligand binding affinity.

  FEBS letters 20070417

• Pathogenic proline mutation in the linker between spectrin repeats: disease caused by spectrin unfolding.

  Blood 20070415

• Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics.

  Bioorganic & medicinal chemistry letters 20070415

• Endogenously generated hydrogen peroxide induces apoptosis via mitochondrial damage independent of NF-kappaB and p53 activation in bovine embryos.

  Theriogenology 20070415

• The protective effects of osmolytes on arginine kinase unfolding and aggregation.

  International journal of biological macromolecules 20070410

• Comparison of C40/82A and P27A C40/82A barstar mutants using 19F NMR.

  Biochemistry 20070410

• Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function.

  Biochemistry 20070410

• Participation of transmembrane proline 82 in angiotensin II AT1 receptor signal transduction.

  Regulatory peptides 20070405

• Conformational preferences of proline analogues with different ring size.

  The journal of physical chemistry. B 20070405

• Post-phosphorylation prolyl isomerisation of gephyrin represents a mechanism to modulate glycine receptors function.

  The EMBO journal 20070404

• Intersectin links WNK kinases to endocytosis of ROMK1.

  The Journal of clinical investigation 20070402

• Efficiency of biochemical protection against toxic effects of accumulated salt differentiates Thellungiella halophila from Arabidopsis thaliana.

  Journal of plant physiology 20070401

• Proline-rich cell wall proteins accumulate in growing regions and phloem tissue in response to water deficit in common bean seedlings.

  Planta 20070401

• Langmuir and Langmuir-Blodgett films of proline-rich N-terminal domain peptide of gamma-zein.

  Colloids and surfaces. B, Biointerfaces 20070401

• Involvement of group II metabotropic glutamate receptors in stress-induced behavioural sensitization.

  Psychopharmacology 20070401

• A cross-reactive material positive variant of coagulation factor XI (FXIP520L) with a catalytic defect.

  Journal of thrombosis and haemostasis : JTH 20070401

• Binding affinity of proanthocyanidin from waste Pinus radiata bark onto proline-rich bovine achilles tendon collagen type I.

  Chemosphere 20070401

• The role of the amino acid residue at alpha1:189 in the binding of neuromuscular blocking agents to mouse and human muscle nicotinic acetylcholine receptors.

  British journal of pharmacology 20070401

• Cold exposure and associated metabolic changes in adult tropical beetles exposed to fluctuating thermal regimes.

  The FEBS journal 20070401

• Lack of association between serum adiponectin levels and the Pro12Ala polymorphism in Asian Indians.

  Diabetic medicine : a journal of the British Diabetic Association 20070401

• Evaluation of predicted network modules in yeast metabolism using NMR-based metabolite profiling.

  Genome research 20070401

• Vinylogous Amadori rearrangement: implications in food and biological systems.

  Molecular nutrition & food research 20070401

• Mechanistic aspects and redox properties of hyperthermophilic L-proline dehydrogenase from Pyrococcus furiosus related to dimethylglycine dehydrogenase/oxidase.

  The FEBS journal 20070401

• Mechanism and biological role of profilin-Srv2/CAP interaction.

  Journal of cell science 20070401

• Transgenic mice that express normal and mutated amelogenins.

  Journal of dental research 20070401

• The risk for thromboembolic disease in lupus anticoagulant patients due to pathways involving P-selectin and CD154.

  Thrombosis and haemostasis 20070401

• SCH 503034, a novel hepatitis C virus protease inhibitor, plus pegylated interferon alpha-2b for genotype 1 nonresponders.

  Gastroenterology 20070401

• Treatment of hepatitis C: don't put all your eggs in one basket!

  Gastroenterology 20070401

• Three novel single nucleotide polymorphisms (SNPs) of CYP2S1 gene in Japanese individuals.

  Drug metabolism and pharmacokinetics 20070401

• Construction and analysis of self-cloning sake yeasts that accumulate proline.

  Journal of bioscience and bioengineering 20070401

• FGF2 effects in periosteal fibroblasts bearing the FGFR2 receptor Pro253 Arg mutation.

  Cytokine 20070401

• Leaf biochemistry of Lycopersicon esculentum Mill. at different stages of plant development as affected by mercury treatment.

  Journal of environmental biology 20070401

• Salt stress enhances proline utilization in the apical region of barley roots.

  Biochemical and biophysical research communications 20070330

• Enantioselective cyanosilylation of alpha,alpha-dialkoxy ketones catalyzed by proline-derived in-situ-prepared N-oxide as bifunctional organocatalyst.

  The Journal of organic chemistry 20070330

• Regiospecific organocatalytic asymmetric aldol reaction of methyl ketones and alpha,beta-unsaturated trifluoromethyl ketones.

  Organic letters 20070329

• Purification, reconstitution, and characterization of the CpxRAP envelope stress system of Escherichia coli.

  The Journal of biological chemistry 20070323

• Methyl jasmonate and salicylic acid induced oxidative stress and accumulation of phenolics in Panax ginseng bioreactor root suspension cultures.

  Molecules (Basel, Switzerland) 20070323

• Cooperativity in the interaction of synthetic CD40L mimetics with CD40 and its implication in cell signaling.

  Biochemistry 20070320

• GPX1 Pro198Leu polymorphism, interactions with smoking and alcohol consumption, and risk for lung cancer.

  Cancer letters 20070318

• Beta-sheet containment by flanking prolines: molecular dynamic simulations of the inhibition of beta-sheet elongation by proline residues in human prion protein.

  Biophysical journal 20070315

• Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population.

  International journal of cancer 20070315

• Structural modifications of (1S,3S)-3-amino-4-difluoromethylenecyclopentanecarboxylic acid, a potent irreversible inhibitor of GABA aminotransferase.

  Bioorganic & medicinal chemistry letters 20070315

• Role of nuclear factor kappa B (NF-kappaB) in oxidative stress-induced defective dopamine D1 receptor signaling in the renal proximal tubules of Sprague-Dawley rats.

  Free radical biology & medicine 20070315

• Essential role of proline isomerization in stefin B tetramer formation.

  Journal of molecular biology 20070309

• Mutational analyses define helix organization and key residues of a bacterial membrane energy-transducing complex.

  Journal of molecular biology 20070309

• Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation.

  The EMBO journal 20070307

• Abl-SH3 binding protein 2, 3BP2, interacts with CIN85 and HIP-55.

  FEBS letters 20070306

• An efficient synthesis of enantiomerically pure (R)-pipecolic acid, (S)-proline, and their N-alkylated derivatives.

  The Journal of organic chemistry 20070302

• Diastereoselective synthesis of 4,5'-bis-proline compounds via reductive dimerization of N-acyloxyiminium ions.

  The Journal of organic chemistry 20070302

• Elimination of the C-cap in ubiquitin - structure, dynamics and thermodynamic consequences.

  Biophysical chemistry 20070301

• PI3-kinase-dependent electrogenic intestinal transport of glucose and amino acids.

  Pflugers Archiv : European journal of physiology 20070301

• Structure of the first transmembrane domain of the neuronal acetylcholine receptor beta2 subunit.

  Biophysical journal 20070301

• Synthesis and structure-activity relationship of N-acyl-Gly-, N-acyl-Sar- and N-blocked-boroPro inhibitors of FAP, DPP4, and POP.

  Bioorganic & medicinal chemistry letters 20070301

• Aquaporin-11 containing a divergent NPA motif has normal water channel activity.

  Biochimica et biophysica acta 20070301

• Diastereoselective synthesis of glycosylated prolines as alpha-glucosidase inhibitors and organocatalyst in asymmetric aldol reaction.

  Bioorganic & medicinal chemistry letters 20070301

• Effect of sodium chloride on the response of the halophyte species Sesuvium portulacastrum grown in mannitol-induced water stress.

  Journal of plant research 20070301

• Improving cell-free protein synthesis for stable-isotope labeling.

  Journal of biomolecular NMR 20070301

• Leucine 7-proline 7 polymorphism in the signal peptide of neuropeptide Y is not a risk factor for exudative age-related macular degeneration.

  Acta ophthalmologica Scandinavica 20070301

• A new mutation in the SH3BP2 gene showing reduced penetrance in a family affected with cherubism.

  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20070301

• Specific targeted antiviral therapy for hepatitis C.

  Current gastroenterology reports 20070301

• Human dipeptidyl peptidase III acts as a post-proline-cleaving enzyme on endomorphins.

  Biological chemistry 20070301

• Enzymatic synthesis of dehydroderivatives from proline-containing cyclic dipeptides and their effects toward cell division.

  Bioscience, biotechnology, and biochemistry 20070301

• Dinitrophenyl derivatization of imino acids, spectral characteristics and HPLC analysis: application in urinary peptide-derived hydroxyproline and proline assay.

  Annals of clinical biochemistry 20070301

• Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis.

  Gastroenterology 20070301

• Craniofacial morphology in Muenke syndrome.

  The Journal of craniofacial surgery 20070301

• Is low-frequency distribution of TGF-beta genotype associated with increased risk for end-stage renal disease?

  DNA and cell biology 20070301

• [Effect of polyethylene glycol on the regeneration of the callus of Pogonatherum paniceum under different culture conditions].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20070301

• [Effects of lead acetate on transcription activity of nuclear factor-kappaB in PC12 cells].

  Wei sheng yan jiu = Journal of hygiene research 20070301

• [Drugs for hepatitis B and C infection].

  Nihon rinsho. Japanese journal of clinical medicine 20070227

• Prolyl cis-trans Isomerization as a molecular timer in Crk signaling.

  Molecular cell 20070223

• Huperzine A protects C6 rat glioma cells against oxygen-glucose deprivation-induced injury.

  FEBS letters 20070220

• Glycogen synthase kinase-3 phosphorylates CdGAP at a consensus ERK 1 regulatory site.

  The Journal of biological chemistry 20070209

• Proline cis-trans isomerization controls autoinhibition of a signaling protein.

  Molecular cell 20070209

• Mutational analysis revealed that conservation of hepatitis B virus reverse transcriptase residue 306 (rtP306) is crucial for encapsidation of pregenomic RNA.

  FEBS letters 20070206

• Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs.

  Journal of molecular biology 20070202

• The effect of abiotic stresses on carbohydrate status of olive shoots (Olea europaea L.) under in vitro conditions.

  Journal of plant physiology 20070201

• Effect of heavy metal stress on proline, malondialdehyde, and superoxide dismutase activity in the cyanobacterium Spirulina platensis-S5.

  Ecotoxicology and environmental safety 20070201

• Polyamine metabolism in sunflower plants under long-term cadmium or copper stress.

  Amino acids 20070201

• Peroxisome proliferator-activated [corrected] receptor-gamma2 [corrected] Pro12Ala, interaction with alcohol intake and NSAID use, in relation to risk of breast cancer in a prospective study of Danes.

  Carcinogenesis 20070201

• Thermodynamic effects of proline introduction on protein stability.

  Proteins 20070201

• Differential involvement of NF-kappaB and MAP kinase pathways in the generation of inflammatory cytokines by human neutrophils.

  Journal of leukocyte biology 20070201

• Insulin-induced activation of hypoxia-inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase.

  American journal of physiology. Heart and circulatory physiology 20070201

• Spectroscopic rationalization of the separation abilities of decaproline chiral selector in dichloromethane-isopropanol solvent mixture.

  Chirality 20070201

• High affinity Grb2-SH3 domain ligand incorporating Cbeta-substituted prolines in a Sos-derived decapeptide.

  Bioorganic & medicinal chemistry 20070201

• Role of proline residues in conferring thermostability on aqualysin I.

  Journal of biochemistry 20070201

• The SH3 domain of a M7 interacts with its C-terminal proline-rich region.

  Protein science : a publication of the Protein Society 20070201

• Cloning and characterization of scale beta-keratins in the differentiating epidermis of geckoes show they are glycine-proline-serine-rich proteins with a central motif homologous to avian beta-keratins.

  Developmental dynamics : an official publication of the American Association of Anatomists 20070201

• On the role of prolyl oligopeptidase in health and disease.

  Neuropeptides 20070201

• Proline reduces brain cytochrome c oxidase: prevention by antioxidants.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20070201

• The Thr715Pro polymorphism of the P-selectin gene is not associated with ischemic stroke risk.

  Stroke 20070201

• Catalytic implications of the higher plant ADP-glucose pyrophosphorylase large subunit.

  Phytochemistry 20070201

• Two novel epilepsy-linked mutations leading to a loss of function of LGI1.

  Archives of neurology 20070201

• Recent progress in the improvement of the coupling efficiency of 'difficult sequences' in peptide synthesis.

  Yao xue xue bao = Acta pharmaceutica Sinica 20070201

• An anti-urokinase plasminogen activator receptor (uPAR) antibody: crystal structure and binding epitope.

  Journal of molecular biology 20070126

• Biophysical characterisation of the small ankyrin repeat protein myotrophin.

  Journal of molecular biology 20070126

• Azidoproline containing helices: stabilization of the polyproline II structure by a functionalizable group.

  Journal of the American Chemical Society 20070124

• Mechanism of the kinetically-controlled folding reaction of subtilisin.

  Biochemistry 20070123

• Polypeptide motions are dominated by peptide group oscillations resulting from dihedral angle correlations between nearest neighbors.

  Biochemistry 20070123

• Direct demonstration of the flexibility of the glycosylated proline-threonine linker in the Cellulomonas fimi Xylanase Cex through NMR spectroscopic analysis.

  The Journal of biological chemistry 20070119

• Diastereocontrolled synthesis of enantioenriched 3,4-disubstituted beta-prolines.

  The Journal of organic chemistry 20070119

• Proline-rich regions in transcriptional complexes: heading in many directions.

  Science's STKE : signal transduction knowledge environment 20070116

• HD-PTP and Alix share some membrane-traffic related proteins that interact with their Bro1 domains or proline-rich regions.

  Archives of biochemistry and biophysics 20070115

• Structural basis for the platelet-collagen interaction: the smallest motif within collagen that recognizes and activates platelet Glycoprotein VI contains two glycine-proline-hydroxyproline triplets.

  The Journal of biological chemistry 20070112

• Interaction between the SH3 domains and C-terminal proline-rich region in NADPH oxidase organizer 1 (Noxo1).

  Biochemical and biophysical research communications 20070112

• Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 'cherubism' mice.

  Cell 20070112

• Proline organocatalysis as a new tool for the asymmetric synthesis of ulosonic acid precursors.

  Chemical communications (Cambridge, England) 20070107

• A novel Cdc42-interacting domain of the yeast polarity establishment protein Bem1. Implications for modulation of mating pheromone signaling.

  The Journal of biological chemistry 20070105

• Ameliorative effect of pyrrolidinedithiocarbamate on acetic acid-induced colitis in rats.

  European journal of pharmacology 20070105

• Glutamate-related gene expression changes with age in the mouse auditory midbrain.

  Brain research 20070105

• Myocyte enhancing factor-2A in Alzheimer's disease: genetic analysis and association with MEF2A-polymorphisms.

  Neuroscience letters 20070103

• Plantainoside D protects adriamycin-induced apoptosis in H9c2 cardiac muscle cells via the inhibition of ROS generation and NF-kappaB activation.

  Life sciences 20070102

• Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis.

  Molecular and cellular biochemistry 20070101

• Malignant hyperthermia mutation sites in the Leu2442-Pro2477 (DP4) region of RyR1 (ryanodine receptor 1) are clustered in a structurally and functionally definable area.

  The Biochemical journal 20070101

• The homozygous P582S mutation in the oxygen-dependent degradation domain of HIF-1 alpha is associated with increased risk for prostate cancer.

  The Prostate 20070101

• Nicotine and biochanin A, but not cigarette smoke, induce anti-inflammatory effects on keratinocytes and endothelial cells in patients with Behçet's disease.

  The Journal of investigative dermatology 20070101

• The organic osmolytes betaine and proline are transported by a shared system in early preimplantation mouse embryos.

  Journal of cellular physiology 20070101

• A case of Muir-Torre syndrome associated with mucinous hepatic cholangiocarcinoma and a novel germline mutation of the MSH2 gene.

  Familial cancer 20070101

• Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms.

  Lung cancer (Amsterdam, Netherlands) 20070101

• A single proline substitution is critical for the thermostabilization of Clostridium beijerinckii alcohol dehydrogenase.

  Proteins 20070101

• Involvement of hyperprolinemia in cognitive and psychiatric features of the 22q11 deletion syndrome.

  Human molecular genetics 20070101

• The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis.

  Human molecular genetics 20070101

• Evidence of asymmetric autocatalysis in organocatalytic reactions.

  Angewandte Chemie (International ed. in English) 20070101

• Does the ornithine-alpha-ketoglutarate ratio influence ornithine alpha-ketoglutarate metabolism in healthy rats?

  Metabolism: clinical and experimental 20070101

• Proline-catalyzed mannich reaction of aldehydes with N-boc-imines.

  Angewandte Chemie (International ed. in English) 20070101

• Human prostacyclin receptor structure and function from naturally-occurring and synthetic mutations.

  Prostaglandins & other lipid mediators 20070101

• Sequences, geographic variations and molecular phylogeny of venom phospholipases and threefinger toxins of eastern India Bungarus fasciatus and kinetic analyses of its Pro31 phospholipases A2.

  The FEBS journal 20070101

• Biological and structural characterization of new linear gomesin analogues with improved therapeutic indices.

  Biopolymers 20070101

• Structural basis for modulation of Kv4 K+ channels by auxiliary KChIP subunits.

  Nature neuroscience 20070101

• A novel missense mutation (p.P52R) in amelogenin gene causing X-linked amelogenesis imperfecta.

  Journal of dental research 20070101

• Switch-peptides as folding precursors in self-assembling peptides and amyloid fibrillogenesis.

  Biopolymers 20070101

• Solid-phase synthesis of a library of pyrrolo[2,1-c][1,4]benzodiazepine-5,11-diones with potential antitubercular activity.

  Journal of combinatorial chemistry 20070101

• A spiroisoxazolinoproline-based amino acid scaffold for solid phase and one-bead-one-compound library synthesis.

  Journal of combinatorial chemistry 20070101

• The Pro12Ala polymorphism in PPARgamma2 gene affects lipid parameters in Greek primary school children: A case of gene-to-gender interaction.

  The American journal of the medical sciences 20070101

• Integrin beta3 Leu33Pro polymorphism and risk of hip fracture: 25 years follow-up of 9233 adults from the general population.

  Pharmacogenetics and genomics 20070101

• Alteration of the proline at position 7 of the HIV-1 spacer peptide p1 suppresses viral infectivity in a strain dependent manner.

  Current HIV research 20070101

• Lys, pro and trp are critical core amino acid residues recognized by FUM20, a monoclonal antibody against serine protease pan-fungal allergens.

  International archives of allergy and immunology 20070101

• Involvement of loops L2 and L4 of ribonucleolytic toxin restrictocin in its functional activity.

  Protein and peptide letters 20070101

• Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress.

  Neurochemical research 20070101

• Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism is associated with the susceptibility to ischemic stroke in Taeeumin classified by Sasang medicine.

  Neurological research 20070101

• [Genetic transformation of buckwheat ( Fagopyrum esculentum Moench ) with AtNHX1 gene and regeneration of salt-tolerant transgenic plants].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20070101

• [Establishment of a transgenic cell model for preliminary screening of chemopreventive agents].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20070101

• Stabilization of the zwitterionic structure of proline by an alkylammonium ion in the gas phase.

  Angewandte Chemie (International ed. in English) 20070101

• UVB-induced IL-18 production in human keratinocyte cell line NCTC 2544 through NF-kappaB activation.

  Cytokine 20070101

• L-proline-catalyzed enantioselective one-pot cross-Mannich reaction of aldehydes.

  Nature protocols 20070101

• Role of receptor and nonreceptor protein tyrosine kinases in H2O2-induced PKB and ERK1/2 signaling.

  Cell biochemistry and biophysics 20070101

• Myocilin mutations among primary open angle glaucoma patients of Kanyakumari district, South India.

  Molecular vision 20070101

• Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene is associated with greater insulin sensitivity and decreased risk of type 2 diabetes in an Iranian population.

  Clinical chemistry and laboratory medicine 20070101

• A way to highly enantiomerically enriched aza-Morita-Baylis-Hillman-type products.

  Angewandte Chemie (International ed. in English) 20070101

• 655Val and 1170Pro ERBB2 SNPs in familial breast cancer risk and BRCA1 alterations.

  Cellular oncology : the official journal of the International Society for Cellular Oncology 20070101

• Physiological and metabolic changes of Cucurbita pepo leaves in response to zucchini yellow mosaic virus (ZYMV) infection and salicylic acid treatments.

  Plant physiology and biochemistry : PPB 20070101

• The rare Hb Showa-Yakushiji [beta110(G12)Leu-->Pro, CTG-->CCG] in combination with an alpha gene triplication found in a Dutch patient during her first pregnancy examination.

  Hemoglobin 20070101

• The first case of Hb Groene Hart [alpha119(H2)Pro-->Ser, CCT-->TCT (alpha1)] homozygosity confirms that a thalassemia phenotype is associated with this abnormal hemoglobin variant.

  Hemoglobin 20070101

• Peroxisome proliferator-activated receptor gamma polymorphism Pro12Ala is associated with nephropathy in type 2 diabetes.

  Journal of diabetes and its complications 20070101

• Functional characterization of a novel CFTR mutation P67S identified in a patient with atypical cystic fibrosis.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

• Pro370Leu mutant myocilin disturbs the endoplasm reticulum stress response and mitochondrial membrane potential in human trabecular meshwork cells.

  Molecular vision 20070101

• Association of TP53 codon 72 polymorphism and the outcome of adjuvant therapy in breast cancer patients.

  Breast cancer research : BCR 20070101

• Allelic variation in the NPY gene in 14 Indian populations.

  Journal of human genetics 20070101

• Design and synthesis of a 3,4-dehydroproline amide discovery library.

  Journal of combinatorial chemistry 20070101

• Improving culture conditions for temporomandibular joint disc tissue engineering.

  Cells, tissues, organs 20070101

• TP53 codon 72 polymorphism in 12 populations of insular Southeast Asia and Oceania.

  Journal of human genetics 20070101

• Pharmacokinetic enhancement of the hepatitis C virus protease inhibitors VX-950 and SCH 503034 by co-dosing with ritonavir.

  Antiviral chemistry & chemotherapy 20070101

• [Decrease in the glutamate release may contribute to the neuroprotective action of the novel neuroleptic drug dilept].

  Eksperimental'naia i klinicheskaia farmakologiia 20070101

• A novel mutation of the Keratin 12 gene responsible for a severe phenotype of Meesmann's corneal dystrophy.

  Molecular vision 20070101

• Novel mutations in the FOXC1 gene in Japanese patients with Axenfeld-Rieger syndrome.

  Molecular vision 20070101

• Synthesis and biological activity of mixed ligand dioxouranium(VI) and thorium(IV) complexes.

  Acta poloniae pharmaceutica 20070101

• First report of phytochelatins in a mushroom: induction of phytochelatins by metal exposure in Boletus edulis.

  Mycologia 20070101

• [Regulation for proline biosynthesis in proteobacteria].

  Molekuliarnaia biologiia 20070101

• Practical Proline-catalyzed asymmetric Mannich reaction of aldehydes with N-Boc-imines.

  Nature protocols 20070101

• Proline-modified DNA as catalyst of the aldol reaction.

  Angewandte Chemie (International ed. in English) 20070101

• Inhibitory effects of a nutrient mixture on human testicular cancer cell line NT 2/DT matrigel invasion and MMP activity.

  Medical oncology (Northwood, London, England) 20070101

• Inhibition of glioma cell line A-172 MMP activity and cell invasion in vitro by a nutrient mixture.

  Medical oncology (Northwood, London, England) 20070101

• Regio- and enantioselective direct oxyamination reaction of aldehydes catalyzed by alpha,alpha-diphenylprolinol trimethylsilyl ether.

  Angewandte Chemie (International ed. in English) 20070101

• Effects of osmolytes on protein folding and aggregation in cells.

  Methods in enzymology 20070101

• Mechanisms of high salinity tolerance in plants.

  Methods in enzymology 20070101

• Interaction of alpha-actinin-4 with class I PxxP motif-containing OK/SW-CL.16 protein.

  Nephron. Experimental nephrology 20070101

• [The novel R252P mutation of the RHO gene in patients with retinitis pigmentosa from Bashkortostan].

  Molekuliarnaia biologiia 20070101

• Phytoremediation of urban wastewater by model wetlands with ornamental hydrophytes.

  Journal of environmental sciences (China) 20070101

• Plant growth, water and proline content and total antioxidant capacity (TAC) in strawberry cv. 'elsanta' under water deficit.

  Communications in agricultural and applied biological sciences 20070101

• Chronic imipramine treatment reduces inhibitory properties of group II mGlu receptors without affecting their density or affinity.

  Pharmacological reports : PR 20070101

• Vitamin B6 related epilepsy during childhood.

  Chang Gung medical journal 20070101

• Evaluating coupling procedures for synthesis of lna-Peptide conjugates.

  Nucleosides, nucleotides & nucleic acids 20070101

• Differential resistance to cell entry by porcine endogenous retrovirus subgroup A in rodent species.

  Retrovirology 20070101

• Compatible solute accumulation and stress-mitigating effects in barley genotypes contrasting in their salt tolerance.

  Journal of experimental botany 20070101

• [Frequency of the Pro 12Ala polymorphism of PPARgamma2 gene in Ukrainian population and its possible role in development of metabolic syndrome].

  TSitologiia i genetika 20070101

• Cell-penetrating proline-rich peptidomimetics.

  Methods in molecular biology (Clifton, N.J.) 20070101

• Biomimetic organocatalytic C-C-bond formations.

  Ernst Schering Foundation symposium proceedings 20070101

• Recoverable, soluble polymer-supported organic catalysts.

  Ernst Schering Foundation symposium proceedings 20070101

• New concepts for organocatalysis.

  Ernst Schering Foundation symposium proceedings 20070101

• Suppression of influenza A virus nuclear antigen production and neuraminidase activity by a nutrient mixture containing ascorbic acid, green tea extract and amino acids.

  BioFactors (Oxford, England) 20070101

• Structure of FBP11 WW1-PL ligand complex reveals the mechanism of proline-rich ligand recognition by group II/III WW domains.

  The Journal of biological chemistry 20061229

• Proline scanning mutagenesis reveals non-native fold in the molten globule state of equine beta-lactoglobulin.

  Biochemistry 20061226

• Functional role of the conserved active site proline of triosephosphate isomerase.

  Biochemistry 20061226

• The role of the GX9GX3G motif in the gating of high voltage-activated Ca2+ channels.

  The Journal of biological chemistry 20061222

• Two new missense mutations of GAA in late onset glycogen storage disease type II.

  Journal of the neurological sciences 20061221

• Assembly of 3-acyloxindoles via cui/L-proline-catalyzed intramolecular arylation of beta-keto amides.

  Organic letters 20061221

• Peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism is associated with reduced risk for ischemic stroke with type 2 diabetes.

  Neuroscience letters 20061220

• Evidence for spontaneous resolution of icosahedral proline.

  Journal of the American Chemical Society 20061220

• A novel P755L mutation in LRRK2 gene associated with Parkinson's disease.

  Neuroreport 20061218

• A novel role for proline- and acid-rich basic region leucine zipper (PAR bZIP) proteins in the transcriptional regulation of a BH3-only proapoptotic gene.

  The Journal of biological chemistry 20061215

• Tumor necrosis factor alpha alters Na+-K+ ATPase activity in rat cardiac myocytes: involvement of NF-kappaB, AP-1 and PGE2.

  Life sciences 20061214

• Fluoroproline flip-flop: regiochemical reversal of a stereoelectronic effect on peptide and protein structures.

  Angewandte Chemie (International ed. in English) 20061211

• Proline promoted synthesis of ring-fused homodimers: self-condensation of alpha,beta-unsaturated aldehydes.

  The Journal of organic chemistry 20061208

• Chiral diols: a new class of additives for direct aldol reaction catalyzed by L-proline.

  The Journal of organic chemistry 20061208

• Kinetic rationalization of nonlinear effects in asymmetric catalysis based on phase behavior.

  Angewandte Chemie (International ed. in English) 20061204

• Expanding the phenotypes of the Pro56Ser VAPB mutation: proximal SMA with dysautonomia.

  Muscle & nerve 20061201

• Evidence for the involvement of proline-directed serine/threonine phosphorylation in sperm capacitation.

  Molecular human reproduction 20061201

• A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin.

  Journal of neurochemistry 20061201

• Drought stress response in wheat: physiological and molecular analysis of resistant and sensitive genotypes.

  Plant, cell & environment 20061201

• Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl.

  The FEBS journal 20061201

• Collision-induced dissociative chemical cross-linking reagents and methodology: Applications to protein structural characterization using tandem mass spectrometry analysis.

  Analytical chemistry 20061201

• Structural insights into the specific binding of huntingtin proline-rich region with the SH3 and WW domains.

  Structure (London, England : 1993) 20061201

• L-arginine-threonine-arginine (RTR) tetramer peptide inhibits ulceration in the alkali-injured rabbit cornea.

  Cornea 20061201

• Ischemia/reperfusion injury: The role of CD26/dipeptidyl-peptidase-IV-inhibition in lung transplantation.

  Transplantation proceedings 20061201

• The kinetics of inhibition of Vigna catjang cotyledon and buffalo liver arginase by L-proline and branched-chain amino acids.

  Journal of enzyme inhibition and medicinal chemistry 20061201

• [Signaling pathways in expression of inducible nitric oxide synthase induced by high mobility group box 1 in rat alveolar macrophages].

  Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20061201

• Interaction between FtsW and penicillin-binding protein 3 (PBP3) directs PBP3 to mid-cell, controls cell septation and mediates the formation of a trimeric complex involving FtsZ, FtsW and PBP3 in mycobacteria.

  Molecular microbiology 20061201

• Critical role of the proline-rich region in Huntingtin for aggregation and cytotoxicity in yeast.

  The Journal of biological chemistry 20061124

• Effects on coagulation and fibrinolysis induced by influenza in mice with a reduced capacity to generate activated protein C and a deficiency in plasminogen activator inhibitor type 1.

  Circulation research 20061124

• Altered Na+ channels promote pause-induced spontaneous diastolic activity in long QT syndrome type 3 myocytes.

  Circulation research 20061124

• Calculation of circular dichroism spectra from optical rotatory dispersion, and vice versa, as complementary tools for theoretical studies of optical activity using time-dependent density functional theory.

  The Journal of chemical physics 20061121

• Chicken suprachiasmatic nuclei: II. Autoradiographic and immunohistochemical analysis.

  The Journal of comparative neurology 20061120

• Mapping active site residues in glutamate-5-kinase. The substrate glutamate and the feed-back inhibitor proline bind at overlapping sites.

  FEBS letters 20061113

• Divergent chemical synthesis of prolines bearing fluorinated one-carbon units at the 4-position via nucleophilic 5-endo-trig cyclizations.

  The Journal of organic chemistry 20061110

• Efficient preparation of proline N-carboxyanhydride using polymer-supported bases.

  Organic letters 20061109

• Compound heterozygous mutations P336L and I1660V in the human cardiac sodium channel associated with the Brugada syndrome.

  Circulation 20061107

• The mitochondrial intermembrane loop region of rat carnitine palmitoyltransferase 1A is a major determinant of its malonyl-CoA sensitivity.

  The Journal of biological chemistry 20061103

• Generation of hybrid transgenic silkworms that express Bombyx mori prolyl-hydroxylase alpha-subunits and human collagens in posterior silk glands: Production of cocoons that contained collagens with hydroxylated proline residues.

  Journal of biotechnology 20061101

• HMG-CoA reductase inhibitor simvastatin mitigates VEGF-induced 'inside-out' signaling to extracellular matrix by preventing RhoA activation.

  American journal of physiology. Renal physiology 20061101

• Characterization of proline, citrulline, and uracil auxotrophic plasmid-carrying Neisseria gonorrhoeae strains in Canada, 1993-2003.

  Sexually transmitted diseases 20061101

• Lysophospholipids increase IL-8 and MCP-1 expressions in human umbilical cord vein endothelial cells through an IL-1-dependent mechanism.

  Journal of cellular biochemistry 20061101

• Investigation on the relationship of proline with wheat anti-drought under soil water deficits.

  Colloids and surfaces. B, Biointerfaces 20061101

• Preferential silencing of a common dominant rhodopsin mutation does not inhibit retinal degeneration in a transgenic model.

  Molecular therapy : the journal of the American Society of Gene Therapy 20061101

• Crystal structures of the DNA-binding domain of Escherichia coli proline utilization A flavoprotein and analysis of the role of Lys9 in DNA recognition.

  Protein science : a publication of the Protein Society 20061101

• Proline induces alterations in nucleotide hydrolysis in rat blood serum.

  Molecular and cellular biochemistry 20061101

• Calpain-resistant fragment(s) of alpha-synuclein regulates the synuclein-cleaving activity of 20S proteasome.

  Archives of biochemistry and biophysics 20061101

• Anticancer effect of lysine, proline, arginine, ascorbic acid and green tea extract on human renal adenocarcinoma line 786-0.

  Oncology reports 20061101

• Dual mode of action of Bac7, a proline-rich antibacterial peptide.

  Biochimica et biophysica acta 20061101

• Proline and glycine control protein self-organization into elastomeric or amyloid fibrils.

  Structure (London, England : 1993) 20061101

• Regulatory cytokine gene polymorphisms and risk of colorectal carcinoma.

  Annals of the New York Academy of Sciences 20061101

• Effects of Pro --> peptoid residue substitution on cell selectivity and mechanism of antibacterial action of tritrpticin-amide antimicrobial peptide.

  Biochemistry 20061031

• Regulation of Stat3 transcriptional activity by the conserved LPMSP motif for OSM and IL-6 signaling.

  FEBS letters 20061030

• A p53 genetic polymorphism of gastric cancer: difference between early gastric cancer and advanced gastric cancer.

  World journal of gastroenterology 20061028

• Structure reassignment and synthesis of Jenamidines A1/A2, synthesis of (+)-NP25302, and formal synthesis of SB-311009 analogues.

  The Journal of organic chemistry 20061027

• Hydrazone- and hydrazide-containing N-substituted glycines as peptoid surrogates for expedited library synthesis: application to the preparation of Tsg101-directed HIV-1 budding antagonists.

  Organic letters 20061026

• Conformational preferences of non-prolyl and prolyl residues.

  The journal of physical chemistry. B 20061026

• The conformation of cyclo(-D-Pro-Ala4-) as a model for cyclic pentapeptides of the DL4 type.

  Journal of the American Chemical Society 20061025

• Conformationally restricted dipeptide amides as potent and selective neuronal nitric oxide synthase inhibitors.

  Journal of medicinal chemistry 20061019

• Proline zwitterion dynamics in solution, glass, and crystalline state.

  Journal of the American Chemical Society 20061018

• Residual dipolar couplings in short peptides reveal systematic conformational preferences of individual amino acids.

  Journal of the American Chemical Society 20061018

• Mechanism of hypoxia-specific cytotoxicity of procaspase-3 fused with a VHL-mediated protein destruction motif of HIF-1alpha containing Pro564.

  FEBS letters 20061016

• Homogeneous PCR nucleobase quenching assays to detect four mutations that cause neuronal ceroid lipofuscinosis: T75P and R151X in CLN1, and IVS5-1G>C and R208X in CLN2.

  Journal of neuroscience methods 20061015

• p53 Arg72Pro polymorphism and risk of colorectal adenoma and cancer.

  International journal of cancer 20061015

• Discovery of potent, selective 4-fluoroproline-based thrombin inhibitors with improved metabolic stability.

  Bioorganic & medicinal chemistry 20061015

• FNDC3A is required for adhesion between spermatids and Sertoli cells.

  Developmental biology 20061015

• A novel domain on HLA-DRbeta chain regulates the chaperone role of the invariant chain.

  Journal of cell science 20061015

• Trisubstituted (E)-alkene dipeptide isosteres as beta-turn promoters in the gramicidin S cyclodecapeptide scaffold.

  Organic letters 20061012

• Optimization of the catalytic asymmetric addition of nitroalkanes to cyclic enones with trans-4,5-methano-L-proline.

  Organic letters 20061012

• Organocatalytic highly enantioselective synthesis of secondary alpha-hydroxyphosphonates.

  Organic letters 20061012

• Conformations of N-acetyl-L-prolinamide by two-dimensional infrared spectroscopy.

  The journal of physical chemistry. B 20061012

• Specific cleavage of DJ-1 under an oxidative condition.

  Neuroscience letters 20061009

• Characterization of amyotrophic lateral sclerosis-linked P56S mutation of vesicle-associated membrane protein-associated protein B (VAPB/ALS8).

  The Journal of biological chemistry 20061006

• Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bioavailable hepatitis C virus NS3 protease inhibitor: a potential therapeutic agent for the treatment of hepatitis C infection.

  Journal of medicinal chemistry 20061005

• Failure to prolyl hydroxylate hypoxia-inducible factor alpha phenocopies VHL inactivation in vivo.

  The EMBO journal 20061004

• Protein assembly line components in prodigiosin biosynthesis: characterization of PigA,G,H,I,J.

  Journal of the American Chemical Society 20061004

• Can mutations in gamma-actin modulate the toxicity of microtubule targeting agents?

  Journal of the National Cancer Institute 20061004

• Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia.

  Journal of the National Cancer Institute 20061004

• Conformational studies of proline-, thiaproline- and dimethylsilaproline-containing diketopiperazines.

  Journal of peptide science : an official publication of the European Peptide Society 20061001

• L-proline transport by purified cell types of lobster hepatopancreas.

  Journal of experimental zoology. Part A, Comparative experimental biology 20061001

• Characterization of proline-serine-rich carboxyl terminus in human sulfotransferase 2B1b: immunogenicity, subcellular localization, kinetic properties, and phosphorylation.

  Drug metabolism and disposition: the biological fate of chemicals 20061001

• Espins and the actin cytoskeleton of hair cell stereocilia and sensory cell microvilli.

  Cellular and molecular life sciences : CMLS 20061001

• Presence and origin of large amounts of D-proline in the urine of mutant mice lacking D-amino acid oxidase activity.

  Analytical and bioanalytical chemistry 20061001

• Transgenic Medicago truncatula plants that accumulate proline display nitrogen-fixing activity with enhanced tolerance to osmotic stress.

  Plant, cell & environment 20061001

• PPAR-gamma2 Pro12Ala variant, insulin resistance and plasma long-chain polyunsaturated fatty acids in childhood obesity.

  Pediatric research 20061001

• Directed evolution of an artificial bifunctional enzyme, gamma-glutamyl kinase/gamma-glutamyl phosphate reductase, for improved osmotic tolerance of Escherichia coli transformants.

  FEMS microbiology letters 20061001

• Functional effects of intramembranous proline substitutions in the staphylococcal multidrug transporter QacA.

  FEMS microbiology letters 20061001

• iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53.

  Nature genetics 20061001

• Using caffeoyl pyrrolidine derivative LY52, a potential inhibitor of matrix metalloproteinase-2, to suppress tumor invasion and metastasis.

  International journal of molecular medicine 20061001

• Susceptibility of Escherichia coli to L-selenaproline and other L-proline analogues in laboratory culture media and normal human urine.

  Letters in applied microbiology 20061001

• TP53 gene R72P polymorphism analysis in patients with Barrett esophagus.

  Cancer genetics and cytogenetics 20061001

• Role of a proline insertion in the insulin promoter factor 1 (IPF1) gene in African Americans with type 2 diabetes.

  Diabetes 20061001

• A structural model of the SHBG domain of human variant protein S Heerlen.

  Thrombosis and haemostasis 20061001

• p53 tumour suppressor gene polymorphism is associated with recurrent implantation failure.

  Reproductive biomedicine online 20061001

• Abiotic stress generates ROS that signal expression of anionic glutamate dehydrogenases to form glutamate for proline synthesis in tobacco and grapevine.

  The Plant cell 20061001

• In vivo and in vitro antitumor effect of a unique nutrient mixture on lung cancer cell line A-549.

  Experimental lung research 20061001

• [Expression of inducible nitric oxide synthase was regulated by activating nuclear factor kappaB in mouse macrophages stimulated with ureaplasma urealyticum lipid-associated membrane proteins].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20061001

• Structure of N-acetylproline amide in liquid water: experimentally measured and numerically simulated infrared and vibrational circular dichroism spectra.

  The journal of physical chemistry. B 20060928

• Asymmetric multicomponent reactions: diastereoselective synthesis of substituted pyrrolidines and prolines.

  Organic letters 20060928

• The discovery of an enantioselective receptor for (-)-adenosine from a racemic dynamic combinatorial library.

  Journal of the American Chemical Society 20060927

• Stereoelectronic tuning of the structure and stability of the trp cage miniprotein.

  Journal of the American Chemical Society 20060927

• Exploring the role of the active site cysteine in human muscle creatine kinase.

  Biochemistry 20060926

• Crystal structure of Thermus thermophilus Delta1-pyrroline-5-carboxylate dehydrogenase.

  Journal of molecular biology 20060922

• Identification of novel FZD4 mutations in Indian patients with familial exudative vitreoretinopathy.

  Molecular vision 20060921

• Effect of proline rich domain of an RNA-binding protein Sam68 in cell growth process, death and B cell signal transduction.

  Chinese medical journal 20060920

• Correlation of folding kinetics with the number and isomerization states of prolines in three homologous proteins of the RNase family.

  FEBS letters 20060918

• Vagal afferent control of opioidergic effects in rat brainstem circuits.

  The Journal of physiology 20060915

• Late-onset metachromatic leukodystrophy: genotype strongly influences phenotype.

  Neurology 20060912

• CAIR-1/BAG-3 modulates cell adhesion and migration by downregulating activity of focal adhesion proteins.

  Experimental cell research 20060910

• Proline isomerization of histone H3 regulates lysine methylation and gene expression.

  Cell 20060908

• Conformational preferences of proline oligopeptides.

  The journal of physical chemistry. B 20060907

• Synthesis and optimization of peptidomimetics as HIV entry inhibitors against the receptor protein CD4 using STD NMR and ligand docking.

  Organic & biomolecular chemistry 20060907

• Artificial aldolases from peptide dendrimer combinatorial libraries.

  Organic & biomolecular chemistry 20060907

• Purification, characterization, and crystallization of human pyrroline-5-carboxylate reductase.

  Protein expression and purification 20060901

• Transport of L-proline, L-proline-containing peptides and related drugs at mammalian epithelial cell membranes.

  Amino acids 20060901

• Association between the Pro12Ala variant of the peroxisome proliferator-activated receptor-gamma2 gene and increased 24-h diastolic blood pressure in obese patients with type II diabetes.

  Journal of human hypertension 20060901

• The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation.

  The Journal of biological chemistry 20060901

• Combinatorial self-assembly of cyclophilin hCyp-18 ligands through rhenium coordination.

  Chembiochem : a European journal of chemical biology 20060901

• Cyclopeptides of Linum usitatissimum.

  Journal of peptide science : an official publication of the European Peptide Society 20060901

• Contribution of a central proline in model amphipathic alpha-helical peptides to self-association, interaction with phospholipids, and antimicrobial mode of action.

  The FEBS journal 20060901

• Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1.

  Nature structural & molecular biology 20060901

• A novel way to express proline-selectively labeled proteins with a wheat germ cell-free protein synthesis system.

  Journal of biochemistry 20060901

• Mutational and bioinformatics analysis of proline- and glycine-rich motifs in vesicular acetylcholine transporter.

  Journal of neurochemistry 20060901

• Thrombospondin-4 1186G>C (A387P) is a sex-dependent risk factor for myocardial infarction: a large replication study with increased sample size from the same population.

  American heart journal 20060901

• A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain.

  Nature structural & molecular biology 20060901

• Inhibition of ribonuclease and protease activities in arsenic exposed rice seedlings: role of proline as enzyme protectant.

  Journal of plant physiology 20060901

• Small-molecule screening identifies the selanazal drug ebselen as a potent inhibitor of DMT1-mediated iron uptake.

  Chemistry & biology 20060901

• Identification of a novel mutation in the spastin gene (SPG4) in an Italian family with hereditary spastic paresis.

  Panminerva medica 20060901

• The role of protective effects of proline-containing peptides (PGP, PG, and GP) in contractile dysfunction of mesenteric lymphatic vessels in rats with experimental acute peritonitis.

  Bulletin of experimental biology and medicine 20060901

• A novel mutation of PAX3 in a Chinese family with Waardenburg syndrome.

  Molecular vision 20060828

• Synthesis, calpain inhibitory activity, and cytotoxicity of P2-substituted proline and thiaproline peptidyl aldehydes and peptidyl alpha-ketoamides.

  Journal of medicinal chemistry 20060824

• Chirally directed formation of nanometer-scale proline clusters.

  Journal of the American Chemical Society 20060823

• Phosphorylation of amphiphysin I by minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase, a kinase implicated in Down syndrome.

  The Journal of biological chemistry 20060818

• The absolute structural requirement for a proline in the P3'-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold.

  The Journal of biological chemistry 20060818

• A highly practical RCM approach towards a molecular building kit of spirocyclic reverse turn mimics.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060816

• The planar conformation of a strained proline ring: a QM/MM study.

  Proteins 20060815

• The synthesis, structural characterization, and receptor specificity of the alpha-conotoxin Vc1.1.

  The Journal of biological chemistry 20060811

• Enantioselective synthesis of beta-amino esters and its application to the synthesis of the enantiomers of the antidepressant Venlafaxine.

  Chemical communications (Cambridge, England) 20060807

• Synthesis of azasugars through a proline-catalyzed reaction.

  The Journal of organic chemistry 20060804

• Crystal structure of the PP2A phosphatase activator: implications for its PP2A-specific PPIase activity.

  Molecular cell 20060804

• Phosphorylation of the Pro-X-Thr-Pro site in phosphatase inhibitor-2 by cyclin-dependent protein kinase during M-phase of the cell cycle.

  Cellular signalling 20060801

• A case of patient affected by hirsutism carrying the P482S CYP21 gene mutation associated with loss of heterozygosity (LOH).

  Clinica chimica acta; international journal of clinical chemistry 20060801

• Aquaporin subfamily with unusual NPA boxes.

  Biochimica et biophysica acta 20060801

• Biocompatibility of elastin-like polymer poly(VPAVG) microparticles: in vitro and in vivo studies.

  Journal of biomedical materials research. Part A 20060801

• Reciprocal and coordinate regulation of serum amyloid A versus apolipoprotein A-I and paraoxonase-1 by inflammation in murine hepatocytes.

  Arteriosclerosis, thrombosis, and vascular biology 20060801

• Collagen synthesis by mesenchymal stem cells and aortic valve interstitial cells in response to mechanical stretch.

  Cardiovascular research 20060801

• Role of glutathione-S-transferase and codon 72 of P53 genotypes in epithelial ovarian cancer patients.

  Journal of cancer research and clinical oncology 20060801

• Whole genome phage display selects for proline-rich Boi polypeptides against Bem1p.

  Biotechnology letters 20060801

• N-all-trans-retinoyl-L-proline inhibits metastatic potential of hepatocellular carcinoma cells.

  Cell biology international 20060801

• Structure-based synthetic mimicry of discontinuous protein binding sites: inhibitors of the interaction of Mena EVH1 domain with proline-rich ligands.

  Chembiochem : a European journal of chemical biology 20060801

• Myelin protein zero mutation His39Pro: hereditary motor and sensory neuropathy with variable onset, hearing loss, restless legs and multiple sclerosis.

  Journal of neurology, neurosurgery, and psychiatry 20060801

• The Pro78 residue regulates the capacity of the human immunodeficiency virus type 1 Nef protein to inhibit recycling of major histocompatibility complex class I molecules in an SH3-independent manner.

  The Journal of general virology 20060801

• Identification of direct and indirect targets of the Gln3 and Gat1 activators by transcriptional profiling in response to nitrogen availability in the short and long term.

  FEMS yeast research 20060801

• Overexpression of BetS, a Sinorhizobium meliloti high-affinity betaine transporter, in bacteroids from Medicago sativa nodules sustains nitrogen fixation during early salt stress adaptation.

  Molecular plant-microbe interactions : MPMI 20060801

• Growth promoting substance in yeast extract for methylotrophic growth of Candida boidinii.

  Bioscience, biotechnology, and biochemistry 20060801

• Adhesion contact kinetics of HepG2 cells during Hepatitis B virus replication: Involvement of SH3-binding motif in HBX.

  Biochimica et biophysica acta 20060801

• Electroelution of lipoprotein(a) [Lp(a)] from native polyacrylamide gels: a new, simple method to purify Lp(a).

  Journal of biochemical and biophysical methods 20060731

• Dipeptide proline diphenyl phosphonates are potent, irreversible inhibitors of seprase (FAPalpha).

  Biochemical and biophysical research communications 20060728

• Population of on-pathway intermediates in the folding of ubiquitin.

  Journal of molecular biology 20060728

• Design, synthesis, and evaluation of proline and pyrrolidine based melanocortin receptor agonists. A conformationally restricted dipeptide mimic approach.

  Journal of medicinal chemistry 20060727

• The role of hydrogen bonding at the active site of a cupredoxin: the Phe114Pro azurin variant.

  Biochemistry 20060725

• Peripherin/RDS and VMD2 mutations in macular dystrophies with adult-onset vitelliform lesion.

  Molecular vision 20060724

• Electrostatic repulsion as an additional selectivity factor in asymmetric proline catalysis.

  Organic & biomolecular chemistry 20060721

• Fluorination-free synthesis of a 4,4-difluoro-3,3-dimethylproline derivative.

  The Journal of organic chemistry 20060721

• Sugar-assisted kinetic resolution of amino acids and amplification of enantiomeric excess of organic molecules.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060717

• Catalytic IgG from patients with hemophilia A inactivate therapeutic factor VIII.

  Journal of immunology (Baltimore, Md. : 1950) 20060715

• Up-regulation of the fidelity of human DNA polymerase lambda by its non-enzymatic proline-rich domain.

  The Journal of biological chemistry 20060714

• Dynamic positive feedback phosphorylation of mixed lineage kinase 3 by JNK reversibly regulates its distribution to Triton-soluble domains.

  The Journal of biological chemistry 20060714

• Site-directed mutagenesis of proline 52 to glycine in amicyanin converts a true electron transfer reaction into one that is conformationally gated.

  Biochemistry 20060711

• Clinical features of hereditary spastic paraplegia due to spastin mutation.

  Neurology 20060711

• Large nonlinear effect observed in the enantiomeric excess of proline in solution and that in the solid state.

  Angewandte Chemie (International ed. in English) 20060710

• Synthesis and characterization of oligoproline-based molecular assemblies for light harvesting.

  The Journal of organic chemistry 20060707

• Replacement of a proline with silaproline causes a 20-fold increase in the cellular uptake of a Pro-rich peptide.

  Journal of the American Chemical Society 20060705

• Apoptosis induction by Epican Forte in HTLV-1 positive and negative malignant T-cells.

  Leukemia research 20060701

• Adiponectin multimerization is dependent on conserved lysines in the collagenous domain: evidence for regulation of multimerization by alterations in posttranslational modifications.

  Molecular endocrinology (Baltimore, Md.) 20060701

• 4-Fluoroproline derivative peptides: effect on PPII conformation and SH3 affinity.

  Journal of peptide science : an official publication of the European Peptide Society 20060701

• 4,5-Diaryl-1H-pyrrole-2-carboxylates as combretastatin A-4/lamellarin T hybrids: synthesis and evaluation as anti-mitotic and cytotoxic agents.

  Bioorganic & medicinal chemistry 20060701

• Influence of a proton gradient on the transport kinetics of the H+/amino acid cotransporter PAT1 in Caco-2 cells.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060701

• Alanine check points in HNN and HN(C)N spectra.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20060701

• Characterization of recombinant Xenopus laevis type I iodothyronine deiodinase: substitution of a proline residue in the catalytic center by serine (Pro132Ser) restores sensitivity to 6-propyl-2-thiouracil.

  Endocrinology 20060701

• Modeling proline ligation in the heme-dependent CO sensor, CooA, using small-molecule analogs.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20060701

• Comparative 35S-sulfate and 3H-proline metabolism within the interdental septal bone and adjacent periodontal ligament.

  The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 20060701

• New highly potent GABA uptake inhibitors selective for GAT-1 and GAT-3 derived from (R)- and (S)-proline and homologous pyrrolidine-2-alkanoic acids.

  European journal of medicinal chemistry 20060701

• De novo tubular nanostructure design based on self-assembly of beta-helical protein motifs.

  Structure (London, England : 1993) 20060701

• Association between Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma 2 and myocardial infarction in the Chinese Han population.

  Clinical cardiology 20060701

• Development of NaCl-tolerant strain in Chrysanthemum morifolium Ramat. through in vitro mutagenesis.

  Plant biology (Stuttgart, Germany) 20060701

• Evidence that differential gene expression between the halophyte, Thellungiella halophila, and Arabidopsis thaliana is responsible for higher levels of the compatible osmolyte proline and tight control of Na+ uptake in T. halophila.

  Plant, cell & environment 20060701

• Peptidergic correction of behavior in adult progeny of albino rats exposed to acute hypoxia during early organogenesis.

  Bulletin of experimental biology and medicine 20060701

• Adulteration of apple with pear juice: emphasis on major carbohydrates, proline, and arbutin.

  Journal of agricultural and food chemistry 20060628

• Identification of the PXW sequence as a structural gatekeeper of the headpiece C-terminal subdomain fold.

  Journal of molecular biology 20060623

• Proline-catalyzed diastereoselective direct aldol reaction between 4-oxoazetidine-2-carbaldehydes and ketones.

  The Journal of organic chemistry 20060623

• Stereoselective synthesis of (Z)-alkene-containing proline dipeptide mimetics.

  The Journal of organic chemistry 20060623

• Proline/pipecolinic acid-promoted copper-catalyzed P-arylation.

  The Journal of organic chemistry 20060623

• Maximizing the stereochemical diversity of spiro-ladder oligomers.

  Organic letters 20060622

• Expedient synthesis of chiral 1,2- and 1,4-diamines: protecting group dependent regioselectivity in direct organocatalytic asymmetric Mannich reactions.

  Organic letters 20060622

• Catalysis by the second class of tRNA(m1G37) methyl transferase requires a conserved proline.

  Biochemistry 20060620

• R1615P: a novel mutation in ABCA1 associated with low levels of HDL and type II diabetes mellitus.

  International journal of cardiology 20060616

• Alteration of the Fc gamma RIIa dimer interface affects receptor signaling but not ligand binding.

  Journal of immunology (Baltimore, Md. : 1950) 20060615

• PanR1, a dominant negative missense allele of the gene encoding TNF-alpha (Tnf), does not impair lymphoid development.

  Journal of immunology (Baltimore, Md. : 1950) 20060615

• Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding.

  Journal of medicinal chemistry 20060615

• Lariatins, antimycobacterial peptides produced by Rhodococcus sp. K01-B0171, have a lasso structure.

  Journal of the American Chemical Society 20060614

• Beta-turn modified gramicidin S analogues containing arylated sugar amino acids display antimicrobial and hemolytic activity comparable to the natural product.

  Journal of the American Chemical Society 20060614

• Catalytic asymmetric fluorinations.

  Organic & biomolecular chemistry 20060607

• Base-catalysed asymmetric hydroamination/cyclisation of aminoalkenes utilising a dimeric chiral diamidobinaphthyl dilithium salt.

  Chemical communications (Cambridge, England) 20060604

• Solution structure of monomeric BsaL, the type III secretion needle protein of Burkholderia pseudomallei.

  Journal of molecular biology 20060602

• Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice.

  Neurobiology of aging 20060601

• Association between TP53 and p21 genetic polymorphisms and acute side effects of radiotherapy in breast cancer patients.

  Breast cancer research and treatment 20060601

• Ascorbic acid-independent synthesis of collagen in mice.

  American journal of physiology. Endocrinology and metabolism 20060601

• Combining a polar resin and a pseudo-proline to optimize the solid-phase synthesis of a 'difficult sequence'.

  Journal of peptide science : an official publication of the European Peptide Society 20060601

• Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034.

  Antiviral research 20060601

• Butyrate-induced collagen biosynthesis in cultured fibroblasts is independent on alpha2beta1 integrin signalling and undergoes through IGF-I receptor cascade.

  Molecular and cellular biochemistry 20060601

• Generation and analysis of proline mutants in protein G.

  Protein engineering, design & selection : PEDS 20060601

• Physiological changes in gentian axillary buds during two-step preculturing with sucrose that conferred high levels of tolerance to desiccation and cryopreservation.

  Annals of botany 20060601

• Developmental expression of two forms of arginase in Neurospora crassa.

  Biochimica et biophysica acta 20060601

• Mouse bites dogma: how mouse models are changing our views of how P53 is regulated in vivo.

  Cell death and differentiation 20060601

• Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.

  American journal of physiology. Renal physiology 20060601

• Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.

  Nature immunology 20060601

• Discovery of proline sulfonamides as potent and selective hepatitis C virus NS5b polymerase inhibitors. Evidence for a new NS5b polymerase binding site.

  Journal of medicinal chemistry 20060601

• Thermodynamic control of asymmetric amplification in amino acid catalysis.

  Nature 20060601

• Peroxynitrite as an alternative donor of oxygen in HIF-1alpha proline hydroxylation under low oxygen availability.

  Free radical research 20060601

• Reply to 'A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation'.

  Nature medicine 20060601

• [Inhibitory effects of matrix metalloproteinase (MMP) inhibitor LY52 on expression of MMP-2 and MMP-9 and invasive ability of human ovarian carcinoma cell line SKOV3].

  Ai zheng = Aizheng = Chinese journal of cancer 20060601

• Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma gene in women with polycystic ovary syndrome.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20060601

• Mycoplasma genitalium mg200 and mg386 genes are involved in gliding motility but not in cytadherence.

  Molecular microbiology 20060601

• Genetically modified cyanobacterium Nostoc muscorum overproducing proline in response to salinity and osmotic stresses.

  Journal of biosciences 20060601

• The effects of exogenous polyamines on some biochemical changes during drought stress in Ctenanthe setosa (Rosc.) Eichler.

  Acta biologica Hungarica 20060601

• [Antioxidant enzyme activities and proline content in maize seedling and their relationships to cold endurance].

  Ying yong sheng tai xue bao = The journal of applied ecology 20060601

• Enantioselective organocatalytic aminomethylation of aldehydes: a role for ionic interactions and efficient access to beta2-amino acids.

  Journal of the American Chemical Society 20060531

• Ubiquinone accumulates in the mitochondria of yeast mutated in the ubiquinone binding protein, Qcr8p.

  Biochemical and biophysical research communications 20060526

• Theoretical and experimental investigation of the energetics of cis-trans proline isomerization in peptide models.

  The journal of physical chemistry. A 20060525

• Enantioselective organocatalytic formal [3 + 3]-cycloaddition of alpha,beta-unsaturated aldehydes and application to the asymmetric synthesis of (-)-isopulegol hydrate and (-)-cubebaol.

  Organic letters 20060525

• Further support of the role of CYP1B1 in patients with Peters anomaly.

  Molecular vision 20060516

• Diastereopure Fe(II) and Zn(II) complexes derived from a tridentate N,N',N-bis(methyl-L-prolinate)-substituted pyridine ligand.

  Inorganic chemistry 20060515

• Oligomerisation of the developmental regulator proline rich homeodomain (PRH/Hex) is mediated by a novel proline-rich dimerisation domain.

  Journal of molecular biology 20060512

• Screening of the MERTK gene for mutations in Japanese patients with autosomal recessive retinitis pigmentosa.

  Molecular vision 20060509

• Development of drug intermediates by using direct organocatalytic multi-component reactions.

  Organic & biomolecular chemistry 20060507

• Single proline residues can dictate the oxidative folding pathways of cysteine-rich peptides.

  Journal of molecular biology 20060505

• P53 status influences regulation of HSPs and ribosomal proteins by PDTC and radiation.

  Biochemical and biophysical research communications 20060505

• Metabolic changes of Malvasia grapes for wine production during postharvest drying.

  Journal of agricultural and food chemistry 20060503

• Mitochondrial transport in proline catabolism in plants: the existence of two separate translocators in mitochondria isolated from durum wheat seedlings.

  Planta 20060501

• Status epilepticus and hyperprolinaemia following recurrent gelatine administrations in a patient on peritoneal dialysis.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060501

• Growth and physiological responses to supplemental UV-B radiation of two contrasting poplar species.

  Tree physiology 20060501

• Moderate increase of mean daily temperature adversely affects fruit set of Lycopersicon esculentum by disrupting specific physiological processes in male reproductive development.

  Annals of botany 20060501

• Azetidine-2-carboxylic acid in garden beets (Beta vulgaris).

  Phytochemistry 20060501

• Structure of T4moC, the Rieske-type ferredoxin component of toluene 4-monooxygenase.

  Acta crystallographica. Section D, Biological crystallography 20060501

• Mutation of Gly51 to serine in the P-loop of Lactobacillus casei folylpolyglutamate synthetase abolishes activity by altering the conformation of two adjacent loops.

  Acta crystallographica. Section D, Biological crystallography 20060501

• Elevated prolidase activity in keloids: correlation with type I collagen turnover.

  The British journal of dermatology 20060501

• Molecular mechanisms of prothrombotic risk due to genetic variations in platelet genes: Enhanced outside-in signaling through the Pro33 variant of integrin beta3.

  Experimental biology and medicine (Maywood, N.J.) 20060501

• Characterization of prolidase activity using capillary electrophoresis with tris(2,2'-bipyridyl)ruthenium(II) electrochemiluminescence detection and application to evaluate collagen degradation in diabetes mellitus.

  Analytical chemistry 20060501

• Role of genetic polymorphism peroxisome proliferator-activated receptor-gamma2 Pro12Ala on ethnic susceptibility to diabetes in South-Asian and Caucasian subjects: Evidence for heterogeneity.

  Diabetes care 20060501

• The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on glucose/insulin metabolism interact with prenatal exposure to famine.

  Diabetes care 20060501

• Effect of calcium, given before or after a fluoride insult, on hamster secretory amelogenesis in vitro.

  European journal of oral sciences 20060501

• Conformation of the backbone in unfolded proteins.

  Chemical reviews 20060501

• Role of the C-terminal fragment of human transthyretin in abnormal fibrillogenesis.

  Biochemistry. Biokhimiia 20060501

• [Study on ethanol tolerance of Saccharomyces cerevisiae X330 under very high gravity medium].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20060501

• [HPLC-ESI/MS analysis of stachydrine and its metabolites in rat urine].

  Yao xue xue bao = Acta pharmaceutica Sinica 20060501

• [Effects of water stress on the growth of Lonicera japonica and quality of honeysuckle].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060501

• The effects of Co2+ and Zn2+ on the contents of protein, abscisic acid, proline and chlorophyll in bean (Phaseolus vulgaris cv. Strike) seedlings.

  Journal of environmental biology 20060501

• Improvement of proline chiral stationary phases by varying peptide length and linker.

  Journal of chromatography. A 20060428

• Identification of substrates of human protein-tyrosine phosphatase PTPN22.

  The Journal of biological chemistry 20060421

• Two separate and distinct syntheses of stereospecifically deuteriated samples of (2S)-proline.

  Organic & biomolecular chemistry 20060421

• Presymptomatic genetic diagnosis for consulters from a large Chinese family with juvenile open angle glaucoma.

  Molecular vision 20060417

• Synthesis, biological evaluation, and pharmacokinetic study of prolyl-1-piperazinylacetic acid and prolyl-4-piperidinylacetic acid derivatives as VLA-4 antagonists.

  Bioorganic & medicinal chemistry 20060415

• Structure-activity relationship study between Ornithyl-Proline and Lysyl-Proline based tripeptidomimics as angiotensin-converting enzyme inhibitors.

  Bioorganic & medicinal chemistry letters 20060415

• Effect of water deficits on the activity of anti-oxidative enzymes and osmoregulation among three different genotypes of Radix Astragali at seeding stage.

  Colloids and surfaces. B, Biointerfaces 20060415

• The anti-angiogenic His/Pro-rich fragment of histidine-rich glycoprotein binds to endothelial cell heparan sulfate in a Zn2+-dependent manner.

  The Journal of biological chemistry 20060414

• Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases.

  The Journal of biological chemistry 20060414

• A chlorophyll a/b-binding protein homolog that is induced by iron deficiency is associated with enlarged photosystem I units in the eucaryotic alga Dunaliella salina.

  The Journal of biological chemistry 20060414

• ESI-MS study on the aldol reaction catalyzed by L-proline.

  Chemical communications (Cambridge, England) 20060414

• Total synthesis of ent-dihydrocorynantheol by using a proline-catalyzed asymmetric addition reaction.

  Organic letters 20060413

• Mutant murine leukemia virus Gag proteins lacking proline at the N-terminus of the capsid domain block infectivity in virions containing wild-type Gag.

  Virology 20060410

• Proximal renal tubular acidosis and ocular pathology: a novel missense mutation in the gene (SLC4A4) for sodium bicarbonate cotransporter protein (NBCe1).

  Molecular vision 20060410

• Impact of cis-proline analogs on peptide conformation.

  Biopolymers 20060405

• Role of conserved prolines in the structure and function of the Na+/dicarboxylate cotransporter 1, NaDC1.

  Biochemistry 20060404

• Stabilization of the biologically active conformation of the principal neutralizing determinant of HIV-1(IIIB) containing a cis-proline surrogate: 1H NMR and molecular modeling study.

  Biochemistry 20060404

• alpha-Tocopherol and ascorbic acid prevent memory deficits provoked by chronic hyperprolinemia in rats.

  Behavioural brain research 20060403

• Polymorphisms in the 5-hydroxytryptamine 2A receptor and CytochromeP4502D6 genes synergistically predict fluvoxamine-induced side effects in japanese depressed patients.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060401

• Chemotactic peptides: fMLF-OMe analogues incorporating proline-methionine chimeras as N-terminal residue.

  Bioorganic & medicinal chemistry 20060401

• HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060401

• WNT10B mutations in human obesity.

  Diabetologia 20060401

• Understanding regulatory networks and engineering for enhanced drought tolerance in plants.

  Current opinion in plant biology 20060401

• Increased risk of non-small cell lung cancer and frequency of somatic TP53 gene mutations in Pro72 carriers of TP53 Arg72Pro polymorphism.

  Lung cancer (Amsterdam, Netherlands) 20060401

• The product of the SHR3 orthologue of Aspergillus nidulans has restricted range of amino acid transporter targets.

  Fungal genetics and biology : FG & B 20060401

• The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: the Data From an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) study.

  Diabetes 20060401

• Inhibition of matrix metalloproteinase-2 secretion and invasion by human ovarian cancer cell line SK-OV-3 with lysine, proline, arginine, ascorbic acid and green tea extract.

  The journal of obstetrics and gynaecology research 20060401

• Co-lyophilization with D-proline greatly enhances peroxidase's stereoselectivity in a non-aqueous medium.

  Biotechnology letters 20060401

• A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network.

  Cancer cell 20060401

• Effects of molybdenum on antioxidative defense system and membrane lipid peroxidation in winter wheat under low temperature stress.

  Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20060401

• [Effects of exogenous nitric oxide, salicylic acid and hydrogen peroxide on free amino acid and soluble protein contents in tobacco leaves].

  Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20060401

• Two-dimensional electrophoresis study of in vitro pellicle formation and dental caries susceptibility.

  European journal of oral sciences 20060401

• Fibrinogen and prothrombin binding is enhanced to the Pro33 isoform of purified integrin alphaIIbbeta3.

  Journal of thrombosis and haemostasis : JTH 20060401

• Na+ and pH dependence of proline and beta-alanine absorption in rat small intestine.

  Acta physiologica (Oxford, England) 20060401

• Antitumor effect of ascorbic acid, lysine, proline, arginine, and green tea extract on bladder cancer cell line T-24.

  International journal of urology : official journal of the Japanese Urological Association 20060401

• A clinical and molecular-genetic analysis of Chinese patients with lattice corneal dystrophy and novel Thr538Pro mutation in the TGFBI (BIGH3) gene.

  Journal of genetics 20060401

• Aqueous chromatography system using temperature-responsive polymer-modified stationary phases.

  Journal of separation science 20060401

• [Effects of irrigation volume on growth and quality of Lonicera japonica].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060401

• Influence of membrane composition on osmosensing by the betaine carrier BetP from Corynebacterium glutamicum.

  The Journal of biological chemistry 20060324

• Molecular details of Itk activation by prolyl isomerization and phospholigand binding: the NMR structure of the Itk SH2 domain bound to a phosphopeptide.

  Journal of molecular biology 20060324

• Molecular determinants for substrate specificity of the ligand-binding protein OpuAC from Bacillus subtilis for the compatible solutes glycine betaine and proline betaine.

  Journal of molecular biology 20060324

• Improvement of proline enantioselective stationary phases by replacing the 9-fluorenylmethoxycarbonyl group.

  Journal of chromatography. A 20060324

• The special five-membered ring of proline: An experimental and theoretical investigation of alkali metal cation interactions with proline and its four- and six-membered ring analogues.

  The journal of physical chemistry. A 20060323

• Time dependent density functional theory modeling of chiroptical properties of small amino acids in solution.

  The journal of physical chemistry. A 20060323

• Mid-infrared spectroscopy of protected peptides in the gas phase: a probe of the backbone conformation.

  Journal of the American Chemical Society 20060322

• Direct antimicrobial activities of PR-bombesin.

  Life sciences 20060320

• AtGAT1, a high affinity transporter for gamma-aminobutyric acid in Arabidopsis thaliana.

  The Journal of biological chemistry 20060317

• L-proline catalyzed Michael additions of thiophenols to alpha,beta-unsaturated compounds, particularly alpha-enones, in the ionic liquid [bmim]PF6.

  Molecules (Basel, Switzerland) 20060317

• Comparison of amino acid compositions of peptides eluted from HLA-B27 molecules of healthy individuals and patients with ankylosing spondylitis.

  Immunology letters 20060315

• Seco-prolinenitrile inhibitors of dipeptidyl peptidase IV define minimal pharmacophore requirements at P1.

  Bioorganic & medicinal chemistry letters 20060315

• The reversed binding of beta-phenethylamine inhibitors of DPP-IV: X-ray structures and properties of novel fragment and elaborated inhibitors.

  Bioorganic & medicinal chemistry letters 20060315

• Impaired helix 12 dynamics due to proline 892 substitutions in the androgen receptor are associated with complete androgen insensitivity.

  Human molecular genetics 20060315

• Aggregate formation and phosphorylation of neurofilament-L Pro22 Charcot-Marie-Tooth disease mutants.

  Human molecular genetics 20060315

• The protein phosphatase 2A phosphatase activator is a novel peptidyl-prolyl cis/trans-isomerase.

  The Journal of biological chemistry 20060310

• Conversion of trypsin into a Na(+)-activated enzyme.

  Biochemistry 20060307

• The presence of high concentrations of free D-amino acids in human saliva.

  Life sciences 20060306

• Hyperprolinemia is not associated with childhood onset schizophrenia.

  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20060305

• A striking periodicity of the cis/trans isomerization of proline imide bonds in cyclic disulfide-bridged peptides.

  Angewandte Chemie (International ed. in English) 20060303

• Pipecolic acid-catalyzed direct asymmetric mannich reactions.

  Organic letters 20060302

• High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway.

  Cellular signalling 20060301

• Deregulation of cyclin-dependent kinase 2 activity correlates with UVC-induced apoptosis in Chinese hamster ovary cells.

  Journal of cellular biochemistry 20060301

• Growth, compatible solute and salt accumulation of five mycorrhizal fungal species grown over a range of NaCl concentrations.

  Mycorrhiza 20060301

• Insulin-like growth factor-1 prevents Abeta[25-35]/(H2O2)- induced apoptosis in lymphocytes by reciprocal NF-kappaB activation and p53 inhibition via PI3K-dependent pathway.

  Growth factors (Chur, Switzerland) 20060301

• Nuclear factor kappa-B blockade reduces skeletal muscle degeneration and enhances muscle function in Mdx mice.

  Experimental neurology 20060301

• C-prolinylquercetins from the yellow cocoon shell of the silkworm, Bombyx mori.

  Phytochemistry 20060301

• Does irradiation affect the protein composition of saliva?

  Clinical oral investigations 20060301

• Effect of water stress on proline accumulation of genetically modified potatoes (Solanum tuberosum L.) generating fructans.

  Journal of plant physiology 20060301

• Arbuscular mycorrhizal fungi influence growth, osmotic adjustment and photosynthesis of citrus under well-watered and water stress conditions.

  Journal of plant physiology 20060301

• A new mutation in PRKAG2 gene causing hypertrophic cardiomyopathy with conduction system disease and muscular glycogenosis.

  Neuromuscular disorders : NMD 20060301

• Mutations in antiquitin in individuals with pyridoxine-dependent seizures.

  Nature medicine 20060301

• Testing the conformational hypothesis of passive membrane permeability using synthetic cyclic peptide diastereomers.

  Journal of the American Chemical Society 20060301

• Woes of proline: a cautionary kinetic tale.

  Protein science : a publication of the Protein Society 20060301

• Substitutions of prolines examine their role in kinetic trap formation of the caspase recruitment domain (CARD) of RICK.

  Protein science : a publication of the Protein Society 20060301

• High plasticity of the hepatitis B virus capsid revealed by conformational stress.

  Journal of molecular biology 20060224

• The associations of p53 overexpression with p53 codon 72 genetic polymorphism in esophageal cancer.

  Mutation research 20060222

• Electronic control of amide cis-trans isomerism via the aromatic-prolyl interaction.

  Journal of the American Chemical Society 20060222

• Antinociceptive effects and synergistic interaction with morphine of intrathecal metabotropic glutamate receptor 2/3 antagonist in the formalin test of rats.

  Neuroscience letters 20060220

• Clusters of PE and PPE genes of Mycobacterium tuberculosis are organized in operons: evidence that PE Rv2431c is co-transcribed with PPE Rv2430c and their gene products interact with each other.

  FEBS letters 20060220

• Temperature-responsive stationary phase utilizing a polymer of proline derivative for hydrophobic interaction chromatography using an aqueous mobile phase.

  Journal of chromatography. A 20060217

• Immunohistochemical evidence for the localization of neurons containing the putative transmitter L-proline in rat brain.

  Brain research 20060216

• Prolidase deficiency and the biochemical assays used in its diagnosis.

  Analytical biochemistry 20060215

• Synthesis and pharmacochemical study of novel polyfunctional molecules combining anti-inflammatory, antioxidant, and hypocholesterolemic properties.

  Bioorganic & medicinal chemistry letters 20060215

• Chloride ion efflux from liposomes is controlled by sidechains in a channel-forming heptapeptide.

  Chemical communications (Cambridge, England) 20060214

• A direct organocatalytic entry to sphingoids: asymmetric synthesis of D-arabino- and L-ribo-phytosphingosine.

  Chemical communications (Cambridge, England) 20060214

• Factor XIIIa mediated attachment of S. aureus fibronectin-binding protein A (FnbA) to fibrin: identification of Gln103 as a major cross-linking site.

  Biochemistry 20060214

• Phenotypic and cellular expression of two novel connexin32 mutations causing CMT1X.

  Neurology 20060214

• Glucocerebrosidase gene mutations and Parkinson disease in the Norwegian population.

  Neurology 20060214

• Enantiodiscrimination between an N-acetyl-L-cysteine SAM and proline: an in situ spectroscopic and computational study.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20060213

• NMR solution structure of the tandem Src homology 3 domains of p47phox complexed with a p22phox-derived proline-rich peptide.

  The Journal of biological chemistry 20060210

• Identification of a novel spiropiperidine opioid receptor-like 1 antagonist class by a focused library approach featuring 3D-pharmacophore similarity.

  Journal of medicinal chemistry 20060209

• Novel potent hepatitis C virus NS3 serine protease inhibitors derived from proline-based macrocycles.

  Journal of medicinal chemistry 20060209

• Conformational preference in aromatic amides bearing chiral ortho substituents: its origin and application to relayed stereocontrol.

  Organic & biomolecular chemistry 20060207

• Conformational arm-wrestling: battles for stereochemical control in benzamides bearing matched and mismatched chiral 2- and 6-substituents.

  Organic & biomolecular chemistry 20060207

• A biomimetic chromanol cyclization leading to alpha-tocopherol.

  Angewandte Chemie (International ed. in English) 20060206

• Allosteric regulation of Hsp70 chaperones by a proline switch.

  Molecular cell 20060203

• Conformational preference and cis-trans isomerization of 4(R)-substituted proline residues.

  The journal of physical chemistry. B 20060202

• Lipopolysaccharide-induced c-Src expression plays a role in nitric oxide and TNFalpha secretion in macrophages.

  Molecular immunology 20060201

• The Pro279Leu variant in the transcription factor MEF2A is associated with myocardial infarction.

  Journal of medical genetics 20060201

• Involvement of NF-kappaB and glutathione in cytotoxic effects of nitric oxide and taxol on human leukemia cells.

  Leukemia research 20060201

• Four novel connexin 32 mutations in X-linked Charcot-Marie-Tooth disease with phenotypic variability.

  Journal of neurology 20060201

• New synthesis of cis 5-tert-butyl-L-proline via cuprate. Evaluation as a cis proline mimetic in a biological active octapeptide.

  Journal of peptide science : an official publication of the European Peptide Society 20060201

• His36Pro point-mutated proteolipid protein retained in the endoplasmic reticulum of oligodendrocytes in the shaking pup.

  Glia 20060201

• Unique translational modification of an invertebrate neuropeptide: a phosphorylated member of the adipokinetic hormone peptide family.

  The Biochemical journal 20060201

• Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H+ -coupled amino-acid transporter hPAT1.

  British journal of pharmacology 20060201

• Metabolic responses to water deficit in two Eucalyptus globulus clones with contrasting drought sensitivity.

  Tree physiology 20060201

• A novel role for proline in plant floral nectars.

  Die Naturwissenschaften 20060201

• Activation of AMP-activated protein kinase enhances angiotensin ii-induced proliferation in cardiac fibroblasts.

  Hypertension (Dallas, Tex. : 1979) 20060201

• Modulation of proline-rich akt substrate survival signaling pathways by oxidative stress in mouse brains after transient focal cerebral ischemia.

  Stroke 20060201

• Roles of Ras and extracellular signal-regulated kinase-dependent IkappaBalpha degradation in oridonin-enhanced phagocytosis of apoptotic cells by human macrophage-like U937 cells.

  International immunopharmacology 20060201

• Mouse tryptophan hydroxylase isoform 2 and the role of proline 447 in enzyme function.

  Journal of neurochemistry 20060201

• Osmotic regulation of 10 wheat (Triticum aestivum L.) genotypes at soil water deficits.

  Colloids and surfaces. B, Biointerfaces 20060201

• Major phosphorylation of SF1 on adjacent Ser-Pro motifs enhances interaction with U2AF65.

  The FEBS journal 20060201

• Immunolocalization and characterization of beta-keratins in growing epidermis of chelonians.

  Tissue & cell 20060201

• Direct asymmetric anti-Mannich-type reactions catalyzed by a designed amino acid.

  Journal of the American Chemical Society 20060201

• C-H activation as a strategic reaction: enantioselective synthesis of 4-substituted indoles.

  Journal of the American Chemical Society 20060201

• NMR analysis of aromatic interactions in designed peptide beta-hairpins.

  Journal of the American Chemical Society 20060201

• Ste20-type kinases: evolutionarily conserved regulators of ion transport and cell volume.

  Physiology (Bethesda, Md.) 20060201

• Capillary electrophoresis for thermodynamic and kinetic studies of peptidyl-proline isomerization by the theoretical plate height model.

  Electrophoresis 20060201

• Role of osmolytes as chemical chaperones during the refolding of aminoacylase.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201

• [Effects of NaCl stress on cation contents in seedlings of two pumpkin varieties].

  Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20060201

• Pentavalent vanadium at concentration of the underground water level enhances the sweet taste sense to glucose in college students.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20060201

• Supplementation effects of hydroxyectoine on proline uptake of downshocked Brevibacterium sp. JCM 6894.

  Journal of bioscience and bioengineering 20060201

• [Evaluation of salt tolerance in Nicotiana tabacum plants bearing an antisense suppressor of the proline dehydrogenase gene].

  Genetika 20060201

• 5-(pyrrolidin-2-yl)-1H-tetrazole and 5-[(pyrrolidin-2-yl)methyl]-1H-tetrazole: proline surrogates with increased potential in asymmetric catalysis.

  Chemistry & biodiversity 20060201

• Chiral 3D architectures with helical channels constructed from polyoxometalate clusters and copper-amino acid complexes.

  Angewandte Chemie (International ed. in English) 20060130

• Molecular and cellular mechanisms of protective immunity to coccidioidomycosis.

  Vaccine 20060123

• Oligoproline effects on polyglutamine conformation and aggregation.

  Journal of molecular biology 20060120

• Crystal structures of tyrosyl-tRNA synthetases from Archaea.

  Journal of molecular biology 20060120

• Biochemical activities of the BOB1 mutant in Methanobacterium thermoautotrophicum MCM.

  Biochemistry 20060117

• Enantioselective alpha-fluorination of carbonyl compounds: organocatalysis or metal catalysis?

  Angewandte Chemie (International ed. in English) 20060116

• Triple helical structure and stabilization of collagen-like molecules with 4(R)-hydroxyproline in the Xaa position.

  Biophysical journal 20060115

• Study on the constructions and activities of three novel hGHRH analogs with N-terminal prolyl modulation+.

  Regulatory peptides 20060115

• Protonated N'-benzyl-N'-prolyl proline hydrazide as highly enantioselective catalyst for direct asymmetric aldol reaction.

  Chemical communications (Cambridge, England) 20060114

• The streptococcal lipoprotein rotamase A (SlrA) is a functional peptidyl-prolyl isomerase involved in pneumococcal colonization.

  The Journal of biological chemistry 20060113

• A C-terminal domain in KCC2 confers constitutive K+-Cl- cotransport.

  The Journal of biological chemistry 20060113

• Destabilization of human IAPP amyloid fibrils by proline mutations outside of the putative amyloidogenic domain: is there a critical amyloidogenic domain in human IAPP?

  Journal of molecular biology 20060113

• Dinuclear Zn-catalyzed asymmetric alkynylation of unsaturated aldehydes.

  Journal of the American Chemical Society 20060111

• Quantitative structure-activity relationship of prolyl oligopeptidase inhibitory peptides derived from beta-casein using simple amino acid descriptors.

  Journal of agricultural and food chemistry 20060111

• SlyD proteins from different species exhibit high prolyl isomerase and chaperone activities.

  Biochemistry 20060110

• Induction of a protein-targeted catalytic response in autoimmune prone mice: antibody-mediated cleavage of HIV-1 glycoprotein GP120.

  Biochemistry 20060110

• Mechanistic and functional studies of the interaction of a proline-rich antimicrobial peptide with mammalian cells.

  The Journal of biological chemistry 20060106

• Proline-catalyzed, asymmetric mannich reactions in the synthesis of a DPP-IV inhibitor.

  The Journal of organic chemistry 20060106

• Alternative methods to limit extracellular bacterial activity for enumeration of intracellular bacteria.

  Journal of microbiological methods 20060101

• A rust-inducible gene from flax (fis1) is involved in proline catabolism.

  Planta 20060101

• Oxidative stress in Scenedesmus sp. during short- and long-term exposure to Cu2+ and Zn2+.

  Chemosphere 20060101

• A missense mutation in pstpip2 is associated with the murine autoinflammatory disorder chronic multifocal osteomyelitis.

  Bone 20060101

• Prodrug of proline analogue reduces hypoxic pulmonary hypertension in rats.

  Pulmonary pharmacology & therapeutics 20060101

• Proline 326 in the C terminus of murine CX3CR1 prevents G-protein and phosphatidylinositol 3-kinase-dependent stimulation of Akt and extracellular signal-regulated kinase in Chinese hamster ovary cells.

  The Journal of pharmacology and experimental therapeutics 20060101

• The role of loop ZA and Pro371 in the function of yeast Gcn5p bromodomain revealed through molecular dynamics and experiment.

  Journal of molecular recognition : JMR 20060101

• The orphan transporter v7-3 (slc6a15) is a Na+-dependent neutral amino acid transporter (B0AT2).

  The Biochemical journal 20060101

• Effects of i and i+3 residue identity on cis-trans isomerism of the aromatic(i+1)-prolyl(i+2) amide bond: implications for type VI beta-turn formation.

  Biopolymers 20060101

• Critical structure-function determinants within the N-terminal region of pulmonary surfactant protein SP-B.

  Biophysical journal 20060101

• Effect of mutation of the tetratricopeptide repeat and asparatate-proline 2 domains of Sti1 on Hsp90 signaling and interaction in Saccharomyces cerevisiae.

  Genetics 20060101

• Saethre-Chotzen syndrome caused by TWIST 1 gene mutations: functional differentiation from Muenke coronal synostosis syndrome.

  European journal of human genetics : EJHG 20060101

• Kinetic and thermodynamic analysis of Bradyrhizobium japonicum PutA-membrane associations.

  Archives of biochemistry and biophysics 20060101

• Injectable formulation of disodium 1-[2-(carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-diolate (PROLI/NO), an ultrafast nitric oxide donor prodrug.

  Journal of pharmaceutical sciences 20060101

• Caenorhabditis elegans expresses three functional profilins in a tissue-specific manner.

  Cell motility and the cytoskeleton 20060101

• Investigation of gas phase ion structure for proline-containing b(2) ion.

  Journal of the American Society for Mass Spectrometry 20060101

• Role of abscisic acid (ABA) and Arabidopsis thaliana ABA-insensitive loci in low water potential-induced ABA and proline accumulation.

  Journal of experimental botany 20060101

• Occurrence and stress response of N-methylproline compounds in Tamarix species.

  Phytochemistry 20060101

• The in vivo effects of the Pro12Ala PPARgamma2 polymorphism on adipose tissue NEFA metabolism: the first use of the Oxford Biobank.

  Diabetologia 20060101

• The proline-rich protein palladin is a binding partner for profilin.

  The FEBS journal 20060101

• Characterization of the theta-type plasmid pCD3.4 from Carnobacterium divergens, and modulation of its host range by RepA mutation.

  Microbiology (Reading, England) 20060101

• Enzymatic debittering of food protein hydrolysates.

  Biotechnology advances 20060101

• Variable tolerance of wetland tree species to combined salinity and waterlogging is related to regulation of ion uptake and production of organic solutes.

  The New phytologist 20060101

• Cdc42 is required for proper growth and development in the fungal pathogen Colletotrichum trifolii.

  Eukaryotic cell 20060101

• Opening the pore hinges on proline.

  Nature chemical biology 20060101

• Changes in the human peritoneal mesothelial cells during aging.

  Kidney international 20060101

• In vivo and in vitro antitumor effect of ascorbic acid, lysine, proline and green tea extract on human melanoma cell line A2058.

  In vivo (Athens, Greece) 20060101

• The significance of amino acids and amino acid-derived molecules in plant responses and adaptation to heavy metal stress.

  Journal of experimental botany 20060101

• Identification of a highly conserved pro-gly doublet in non-animal small heat shock proteins and characterization of its structural and functional roles in Mycobacterium tuberculosis Hsp16.3.

  Biochemistry. Biokhimiia 20060101

• Normal phase high-performance liquid chromatography of pneumocandins: in situ modification of silica with L-proline to separate structural analogues.

  Biotechnology progress 20060101

• Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome amongst the Taiwanese population- not correlated with insulin receptor substrate-1 Gly972Arg/Ala513Pro polymorphism.

  BMC medical genetics 20060101

• Nutrient-regulated gene expression in eukaryotes.

  Biochemical Society symposium 20060101

• [Comparison of anticoagulant effects of regulatory proline-containing oligopeptides. Specificity of glyprolines, semax, and selank and potential of their practical application].

  Izvestiia Akademii nauk. Seriia biologicheskaia 20060101

• In vivo and in vitro antitumor effect of ascorbic acid, lysine, proline, arginine, and green tea extract on human fibrosarcoma cells HT-1080.

  Medical oncology (Northwood, London, England) 20060101

• [Role of the genetic polymorphism of p53 (codon 72) gene in colorectal cancer].

  Arquivos de gastroenterologia 20060101

• The role of proline residues in the dynamics of transmembrane helices: the case of bacteriorhodopsin.

  Molecular membrane biology 20060101

• Inhibition of malignant mesothelioma cell matrix metalloproteinase production and invasion by a novel nutrient mixture.

  Experimental lung research 20060101

• [Reculatory fragments of collagen in gastric mucosa homeostasis].

  Uspekhi fiziologicheskikh nauk 20060101

• Peroxisome proliferator-activated receptor-gamma polymorphism, body mass and prostate cancer risk: evidence for gene-environment interaction.

  Oncology 20060101

• Suppression of human cervical cancer cell lines Hela and DoTc2 4510 by a mixture of lysine, proline, ascorbic acid, and green tea extract.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101

• Transdermal nicotine patch enhances type I collagen synthesis in abstinent smokers.

  Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20060101

• The synergy of ChemMatrix resin and pseudoproline building blocks renders RANTES, a complex aggregated chemokine.

  Biopolymers 20060101

• Divergence in spatial expression patterns and in response to stimuli of tandem-repeat paralogues encoding a novel class of proline-rich proteins in Oryza sativa.

  Journal of experimental botany 20060101

• Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7.

  BMC immunology 20060101

• Effective solvation of alkaline earth ions by proline-rich proteolytic peptides of galectin-3 upon electrospray ionisation.

  Rapid communications in mass spectrometry : RCM 20060101

• Nutritional and osmotic roles of nitrate in a euhalophyte and a xerophyte in saline conditions.

  The New phytologist 20060101

• Protein-protein interactions in signaling cascades.

  Methods in molecular biology (Clifton, N.J.) 20060101

• VHL P25L is not a pathogenic von Hippel-Lindau mutation: a family study.

  Molecular diagnosis & therapy 20060101

• Click chemistry on azidoproline: high-affinity dual antagonist for HIV-1 envelope glycoprotein gp120.

  ChemMedChem 20060101

• Amino acid catabolic pathways of lactic acid bacteria.

  Critical reviews in microbiology 20060101

• P53 codon 11, 72, and 248 gene polymorphisms in endometriosis.

  International journal of biological sciences 20060101

• Does the enhanced tolerance of arbuscular mycorrhizal plants to water deficit involve modulation of drought-induced plant genes?

  The New phytologist 20060101

• Non-protein amino acids in the design of secondary structure scaffolds.

  Methods in molecular biology (Clifton, N.J.) 20060101

• Hereditary hyper-ACE-emia due to the Pro1199Leu mutation of somatic ACE as a potential pitfall in diagnosis: a first family outside Europe.

  Clinical chemistry and laboratory medicine 20060101

• Molecular assay for detection of the common carnitine palmitoyltransferase 1A 1436(C>T) mutation.

  Clinical chemistry and laboratory medicine 20060101

• Compound heterozygous CNGA3 mutations (R436W, L633P) in a Japanese patient with congenital achromatopsia.

  Visual neuroscience 20060101

• A novel mutation in the short-wavelength-sensitive cone pigment gene associated with a tritan color vision defect.

  Visual neuroscience 20060101

• The proline-rich domain and the microtubule binding domain of protein tau acting as RNA binding domains.

  Protein and peptide letters 20060101

• Effect of ascorbic acid, lysine, proline, and green tea extract on human osteosarcoma cell line MNNG-HOS xenografts in nude mice: evaluation of tumor growth and immunohistochemistry.

  Medical oncology (Northwood, London, England) 20060101

• The P1812A and P25T BRCA1 and the 5164del4 BRCA2 mutations: occurrence in high-risk non-Ashkenazi Jews.

  Genetic testing 20060101

• Ocular dominance columns in strabismus.

  Visual neuroscience 20060101

• Rubber Tree (Hevea brasiliensis Muell. Arg).

  Methods in molecular biology (Clifton, N.J.) 20060101

• Flight fuel and neuropeptidergic control of fuel mobilisation in the twig wilter, Holopterna alata (Hemiptera, Coreidae).

  Journal of insect physiology 20060101

• Modeling activated states of GPCRs: the rhodopsin template.

  Journal of computer-aided molecular design 20060101

• Evidence for an association of TP53 codon 72 polymorphism with breast cancer risk.

  Cancer detection and prevention 20060101

• Amino acid contents of infant foods.

  International journal of food sciences and nutrition 20060101

• Hepatic chemoprotective enzyme responses to 2-substituted selenazolidine-4(R)-carboxylic acids.

  Journal of biochemical and molecular toxicology 20060101

• [Effective therapy with a glycine-proline ointment in a patient with recurrent ulcers from prolidase deficiency].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20060101

• Inhibition of pulmonary metastasis of melanoma b16fo cells in C57BL/6 mice by a nutrient mixture consisting of ascorbic Acid, lysine, proline, arginine, and green tea extract.

  Experimental lung research 20060101

• [Derivatives of N-amidinoproline and their use in conventional and solid phase peptide synthesis].

  Bioorganicheskaia khimiia 20060101

• Determinants of positive cooperativity between strychnine-like allosteric modulators and N-methylscopolamine at muscarinic receptors.

  Journal of molecular neuroscience : MN 20060101

• Effect of drought stress at supraoptimal temperature on polyamine concentrations in transgenic soybean with increased proline levels.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101

• A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC).

  Nature protocols 20060101

• Plant adaptation to salinity reduces copper toxicity.

  Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20060101

• Altered light responses of single rod photoreceptors in transgenic pigs expressing P347L or P347S rhodopsin.

  Molecular vision 20051231

• Dynamical binding of proline-rich peptides to their recognition domains.

  Biochimica et biophysica acta 20051230

• The proto-oncoprotein SYT interacts with SYT-interacting protein/co-activator activator (SIP/CoAA), a human nuclear receptor co-activator with similarity to EWS and TLS/FUS family of proteins.

  The Journal of biological chemistry 20051230

• Cdc42 induces activation loop phosphorylation and membrane targeting of mixed lineage kinase 3.

  The Journal of biological chemistry 20051230

• TRP-ML1 is a lysosomal monovalent cation channel that undergoes proteolytic cleavage.

  The Journal of biological chemistry 20051230

• Endogenous siRNAs derived from a pair of natural cis-antisense transcripts regulate salt tolerance in Arabidopsis.

  Cell 20051229

• A stereoelectronic effect on turn formation due to proline substitution in elastin-mimetic polypeptides.

  Journal of the American Chemical Society 20051228

• Ionization of zwitterionic amine substrates bound to monomeric sarcosine oxidase.

  Biochemistry 20051227

• Dissection of Escherichia coli glutamate 5-kinase: functional impact of the deletion of the PUA domain.

  FEBS letters 20051219

• Crystal structure of cone arrestin at 2.3A: evolution of receptor specificity.

  Journal of molecular biology 20051216

• A region C-terminal to the proline-rich core of p47phox regulates activation of the phagocyte NADPH oxidase by interacting with the C-terminal SH3 domain of p67phox.

  Archives of biochemistry and biophysics 20051215

• Microchip capillary electrophoresis with solid-state electrochemiluminescence detector.

  Analytical chemistry 20051215

• Essential role for Pro21 in phospholamban for optimal inhibition of the Ca-ATPase.

  Biochemistry 20051213

• Regulation of the catalytic activity of PTP1B: roles for cell adhesion, tyrosine residue 66, and proline residues 309 and 310.

  Experimental cell research 20051210

• Crystal structures of Delta1-piperideine-2-carboxylate/Delta1-pyrroline-2-carboxylate reductase belonging to a new family of NAD(P)H-dependent oxidoreductases: conformational change, substrate recognition, and stereochemistry of the reaction.

  The Journal of biological chemistry 20051209

• Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells.

  Journal of the National Cancer Institute 20051207

• Binding of the intracellular Fas ligand (FasL) domain to the adaptor protein PSTPIP results in a cytoplasmic localization of FasL.

  The Journal of biological chemistry 20051202

• Synthesis, spectral characterization and biological studies of some organotin(IV) complexes of L-proline, trans-hydroxy-L-proline and L-glutamine.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051201

• Survivin contributes to the anti-apoptotic activities of transforming growth factor alpha in mouse blastocysts through phosphatidylinositol 3'-kinase pathway.

  Biology of reproduction 20051201

• Evaluation of new 18F-labeled amino acids for brain PET.

  Anatomy and embryology 20051201

• Comparative analysis in cereals of a key proline catabolism gene.

  Molecular genetics and genomics : MGG 20051201

• Exogenously supplied compatible solutes rapidly ameliorate NaCl-induced potassium efflux from barley roots.

  Plant & cell physiology 20051201

• Translocation of metals from fly ash amended soil in the plant of Sesbania cannabina L. Ritz: effect on antioxidants.

  Chemosphere 20051201

• Mutagenesis at Pro309 of single-chain urokinase-type plasminogen activator alters its catalytic properties.

  Proteins 20051201

• The major Aeromonas veronii outer membrane protein: gene cloning and sequence analysis.

  Current microbiology 20051201

• Anti-angiogenic effects of a nutrient mixture on human umbilical vein endothelial cells.

  Oncology reports 20051201

• Acyl transfer in clorobiocin biosynthesis: involvement of several proteins in the transfer of the pyrrole-2-carboxyl moiety to the deoxysugar.

  Chembiochem : a European journal of chemical biology 20051201

• Mutations in mtDNA-encoded cytochrome c oxidase subunit genes causing isolated myopathy or severe encephalomyopathy.

  Neuromuscular disorders : NMD 20051201

• Combining in silico tools and NMR data to validate protein-ligand structural models: application to matrix metalloproteinases.

  Journal of medicinal chemistry 20051201

• SHIP2 interaction with the cytoskeletal protein Vinexin.

  The FEBS journal 20051201

• Increased risk of ovarian cancer in integrin beta3 Leu33Pro homozygotes.

  Endocrine-related cancer 20051201

• The polybasic juxtamembrane region of Sso1p is required for SNARE function in vivo.

  Eukaryotic cell 20051201

• [Effects of high temperature on grain filling and some physiological characteristic in flag leaves of hybrid rice].

  Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20051201

• Familial autosomal dominant cortico-basal degeneration with the P301S mutation in the tau gene: an example of phenotype variability.

  Journal of neurology 20051201

• Two novel TP63 mutations associated with the ankyloblepharon, ectodermal defects, and cleft lip and palate syndrome: a skin fragility phenotype.

  Archives of dermatology 20051201

• WW or WoW: the WW domains in a union of bliss.

  IUBMB life 20051201

• Capillary array electrophoresis for the research of asymmetric transformation reaction of L-proline to D-proline.

  Journal of separation science 20051201

• [Inhibition of rat corneal neovascularization by inhibitor of nuclear factor-kappaB].

  [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20051201

• Crystallization and preliminary X-ray diffraction studies of the WW4 domain of the Nedd4-2 ubiquitin-protein ligase.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20051201

• Expression of delta1-pyrroline-5-carboxylate synthetase gene during drought in rice (Oryza sativa L.).

  Indian journal of biochemistry & biophysics 20051201

• Laminated morphology of nontwisting beta-sheet fibrils constructed via peptide self-assembly.

  Journal of the American Chemical Society 20051130

• Local hydration environments of amino acids and dipeptides studied by X-ray spectroscopy of liquid microjets.

  The journal of physical chemistry. B 20051124

• The elongated first fibronectin type III domain of collagen XIV is an inducer of quiescence and differentiation in fibroblasts and preadipocytes.

  The Journal of biological chemistry 20051118

• A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation.

  Biochemical and biophysical research communications 20051118

• Stereoelectronic and steric effects in the collagen triple helix: toward a code for strand association.

  Journal of the American Chemical Society 20051116

• P61A mutation in the factor for inversion stimulation results in a thermostable dimeric intermediate.

  Biochemistry 20051115

• Crystal structures of the wild-type, P1A mutant, and inactivated malonate semialdehyde decarboxylase: a structural basis for the decarboxylase and hydratase activities.

  Biochemistry 20051115

• Thermodynamics and kinetics of formation of the alkaline state of a Lys 79-->Ala/Lys 73-->His variant of iso-1-cytochrome c.

  Biochemistry 20051115

• Chirality organization of ferrocenes bearing dipeptide chains of heterochiral sequence.

  Organic letters 20051110

• Highly enantioselective synthesis of rigid, quaternary 1,4-benzodiazepine-2,5-diones derived from proline.

  Organic letters 20051110

• C2-symmetric bisprolinamide as a highly efficient catalyst for direct aldol reaction.

  Organic letters 20051110

• Neurobiology: triggers for channel opening.

  Nature 20051110

• Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel.

  Nature 20051110

• An access to 3,4-(aminomethano)proline in racemic and enantiomerically pure form.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20051104

• Proline-based macrocyclic inhibitors of the hepatitis C virus: stereoselective synthesis and biological activity.

  Angewandte Chemie (International ed. in English) 20051104

• Differential effects of NF-{kappa}B and p38 MAPK inhibitors and combinations thereof on TNF-{alpha}- and IL-1{beta}-induced proinflammatory status of endothelial cells in vitro.

  American journal of physiology. Cell physiology 20051101

• Aged bovine chondrocytes display a diminished capacity to produce a collagen-rich, mechanically functional cartilage extracellular matrix.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20051101

• Mycorrhizal impact on drought stress tolerance of rose plants probed by chlorophyll a fluorescence, proline content and visual scoring.

  Mycorrhiza 20051101

• Probing the 'additive effect' in the proline and proline hydroxamic acid catalyzed asymmetric addition of nitroalkanes to cyclic enones.

  Chirality 20051101

• beta-cyclodextrin-immobilized (4S)-phenoxy-(S)-proline as a catalyst for direct asymmetric aldol reactions.

  Chirality 20051101

• Marked phenotypic variation in a family with a new myelin protein zero mutation.

  Neuromuscular disorders : NMD 20051101

• The crystal structure of the cis-proline to glycine variant (P114G) of ribonuclease A.

  Protein science : a publication of the Protein Society 20051101

• Structure of infectious prions: stabilization by domain swapping.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051101

• [Peculiarities of epileptic syndrome in children with metabolic disorders of nervous system].

  Georgian medical news 20051101

• Vacuolar functions are involved in stress-protective effect of intracellular proline in Saccharomyces cerevisiae.

  Journal of bioscience and bioengineering 20051101

• Characterization of sulfate, proline, and glucose transport systems in anterior cruciate and medial collateral ligament cells.

  Canadian journal of physiology and pharmacology 20051101

• [Influence of polymorphism pro12Ala of PPARgamma gene on endothelium destruction in patients with diabetes mellitus t. 2].

  Polskie Archiwum Medycyny Wewnetrznej 20051101

• Structural and mutational analyses of the molecular interactions between the catalytic domain of factor XIa and the Kunitz protease inhibitor domain of protease nexin 2.

  The Journal of biological chemistry 20051028

• C-terminal recognition by 14-3-3 proteins for surface expression of membrane receptors.

  The Journal of biological chemistry 20051028

• Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase.

  The Journal of biological chemistry 20051021

• Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1.

  The Journal of biological chemistry 20051021

• Enantiomer separation by counter-current chromatography. Optimisation and drawbacks in the use of L-proline derivatives as chiral selectors.

  Journal of chromatography. A 20051021

• Introduction of a cis-prolyl mimic in position 7 of the peptide hormone oxytocin does not result in antagonistic activity.

  Journal of medicinal chemistry 20051020

• NF-kappaB and Hsp70 are involved in the phospholipase Cgamma1 signaling pathway in colorectal cancer cells.

  Life sciences 20051014

• Structural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesis.

  The Journal of biological chemistry 20051014

• Controlled synthesis of thermoresponsive polymers derived from L-proline via RAFT polymerization.

  Chemical communications (Cambridge, England) 20051014

• Microfluidic chip with electrochemiluminescence detection using 2-(2-aminoethyl)-1-methylpyrrolidine labeling.

  Journal of chromatography. A 20051014

• CuI/L-proline-catalyzed coupling reactions of aryl halides with activated methylene compounds.

  Organic letters 20051013

• pH variation as the switch for chiral recognition in a biomembrane model.

  Journal of the American Chemical Society 20051012

• Catalytic enantioselective 1,3-dipolar cycloaddition reaction of azomethine ylides and alkenes: the direct strategy to prepare enantioenriched highly substituted proline derivatives.

  Angewandte Chemie (International ed. in English) 20051007

• Collagen-like triple helix formation of synthetic (Pro-Pro-Gly)10 analogues: (4(S)-hydroxyprolyl-4(R)-hydroxyprolyl-Gly)10, (4(R)-hydroxyprolyl-4(R)-hydroxyprolyl-Gly)10 and (4(S)-fluoroprolyl-4(R)-fluoroprolyl-Gly)10.

  Journal of peptide science : an official publication of the European Peptide Society 20051001

• Development of a novel serum-free freezing medium for mammalian cells using the silk protein sericin.

  Biotechnology and applied biochemistry 20051001

• Early and sustained inhibition of nuclear factor-kappaB prevents hypertension in spontaneously hypertensive rats.

  The Journal of pharmacology and experimental therapeutics 20051001

• Galectin-1 is an inductor of pancreatic stellate cell activation.

  Cellular signalling 20051001

• Lack of evidence that proline homozygosity at codon 72 of p53 and rare arginine allele at codon 31 of p21, jointly mediate cervical cancer susceptibility among Indian women.

  Gynecologic oncology 20051001

• Differential effects of estrogen on DNA synthesis in human periodontal ligament and breast cancer cells.

  Journal of periodontal research 20051001

• Mutation analysis of CLPTM 1 and PVRL 1 genes in patients with non-syndromic clefts of lip, alveolus and palate.

  Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 20051001

• Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angiogenesis.

  Oncology reports 20051001

• Chemical synthesis of the RGD-protein decorsin: Pro-->Ala replacement reduces protein thermostability.

  Protein engineering, design & selection : PEDS 20051001

• c-Src-dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20051001

• Effect of ischemia reperfusion on sodium-dependent phosphate transport in renal brush border membranes.

  Biochimica et biophysica acta 20051001

• Collagen morphology is not associated with the Ala549Pro polymorphism of the COL1A2 gene.

  Stroke 20051001

• Natural product family 18 chitinase inhibitors.

  Natural product reports 20051001

• Eggshell composition of squamate reptiles: relationship between eggshell permeability and amino acid distribution.

  Journal of chemical ecology 20051001

• Structural studies on recombinant T = 3 capsids of Sesbania mosaic virus coat protein mutants.

  Acta crystallographica. Section D, Biological crystallography 20051001

• Improved proton affinity measurements for proline and modified prolines using triple quadrupole and ion trap mass spectrometers.

  Journal of mass spectrometry : JMS 20051001

• Effect of latanoprost on cultured porcine corneal stromal cells.

  Current eye research 20051001

• Involvement of spinal cord nuclear factor kappaB activation in rat models of proinflammatory cytokine-mediated pain facilitation.

  The European journal of neuroscience 20051001

• N-acetyltransferase Mpr1 confers freeze tolerance on Saccharomyces cerevisiae by reducing reactive oxygen species.

  Journal of biochemistry 20051001

• Peptide and peptidomimetic chiral selectors in liquid chromatography.

  Journal of separation science 20051001

• Laminopathies affecting skeletal and cardiac muscles: clinical and pathophysiological aspects.

  Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology 20051001

• Novel interaction partners of the CD2BP2-GYF domain.

  The Journal of biological chemistry 20050930

• Readily tunable and bifunctional L-prolinamide derivatives: design and application in the direct enantioselective Aldol reactions.

  Organic letters 20050929

• Importance of the GP dipeptide of the antiporter motif and other membrane-embedded proline and glycine residues in tetracycline efflux protein Tet(L).

  Biochemistry 20050927

• Engineered alpha-synuclein prevents wild type and familial Parkin variant fibril formation.

  Biochemical and biophysical research communications 20050923

• The ultimate tryptophan residue of neprilysin 2 is not involved in protein maturation and enzymatic activity.

  Biochemical and biophysical research communications 20050923

• Molecular identification of wheat endoxylanase inhibitor TAXI-II and the determinants of its inhibition specificity.

  Biochemical and biophysical research communications 20050923

• Natural-like function in artificial WW domains.

  Nature 20050922

• Genetic manipulation of proline accumulation influences the concentrations of other amino acids in soybean subjected to simultaneous drought and heat stress.

  Journal of agricultural and food chemistry 20050921

• Exploring the proline-dependent conformational change in the multifunctional PutA flavoprotein by tryptophan fluorescence spectroscopy.

  Biochemistry 20050920

• Effect of multiple prolyl isomerization reactions on the stability and folding kinetics of the notch ankyrin domain: experiment and theory.

  Journal of molecular biology 20050916

• Experimental characterization of the folding kinetics of the notch ankyrin domain.

  Journal of molecular biology 20050916

• Folding cooperativity in a three-stranded beta-sheet model.

  Journal of molecular biology 20050916

• Asymmetric halo-Mannich-type reaction provides access to pyrrolidines and beta-proline derivatives.

  The Journal of organic chemistry 20050916

• Coordinated collagen and muscle protein synthesis in human patella tendon and quadriceps muscle after exercise.

  The Journal of physiology 20050915

• Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes.

  Free radical biology & medicine 20050915

• Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transduction.

  The Biochemical journal 20050915

• Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation.

  The Journal of biological chemistry 20050909

• Puckering transition of 4-substituted proline residues.

  The journal of physical chemistry. B 20050908

• Proline-based modulation of 2,4-diacetylphloroglucinol and viable cell yields in cultures of Pseudomonas fluorescens wild-type and over-producing strains.

  Applied microbiology and biotechnology 20050901

• Responsive modes of Medicago sativa proline dehydrogenase genes during salt stress and recovery dictate free proline accumulation.

  Planta 20050901

• Association analysis of NAD(P)Hratioquinone oxidoreductase (NQO1) Pro187Ser genetic polymorphism and tardive dyskinesia in patients with schizophrenia in Taiwan.

  The international journal of neuropsychopharmacology 20050901

• Hydroxide and proton migration in aquaporins.

  Biophysical journal 20050901

• Accumulation of metals and its effects in Brassica juncea (L.) Czern. (cv. Rohini) grown on various amendments of tannery waste.

  Ecotoxicology and environmental safety 20050901

• A novel mutation L260P of the steroidogenic acute regulatory protein gene in three unrelated patients of Swiss ancestry with congenital lipoid adrenal hyperplasia.

  The Journal of clinical endocrinology and metabolism 20050901

• Fragmentation reactions of deprotonated peptides containing proline. The proline effect.

  Journal of mass spectrometry : JMS 20050901

• Motorcycle exhaust particles induce IL-8 production through NF-kappaB activation in human airway epithelial cells.

  Journal of toxicology and environmental health. Part A 20050901

• Glycine- and proline-rich glycoprotein isolated from Solanum nigrum Linne activates caspase-3 through cytochrome c in HT-29 cells.

  Oncology reports 20050901

• p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1.

  Cell cycle (Georgetown, Tex.) 20050901

• Synthesis and secondary structure of loop 4 of myelin proteolipid protein: effect of a point mutation found in Pelizaeus-Merzbacher disease.

  The journal of peptide research : official journal of the American Peptide Society 20050901

• Two proline-rich peptides from pig (Sus scrofa) salivary glands generated by pre-secretory pathway underlying the action of a proteinase cleaving ProAla bonds.

  Peptides 20050901

• Enhancing Arabidopsis salt and drought stress tolerance by chemical priming for its abscisic acid responses.

  Plant physiology 20050901

• Organocatalytic enantioselective synthesis of metabotropic glutamate receptor ligands.

  Organic letters 20050901

• Serotonin, L-tryptophan, and tryptamine are effective inhibitors of the amino acid transport system PAT1.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050901

• An improved experimental system for determining small folding entropy changes resulting from proline to alanine substitutions.

  Protein science : a publication of the Protein Society 20050901

• Solid-state magic-angle spinning NMR of outer-membrane protein G from Escherichia coli.

  Chembiochem : a European journal of chemical biology 20050901

• Lovastatin reduces nuclear factor kappaB activation induced by C-reactive protein in human vascular endothelial cells.

  Biological & pharmaceutical bulletin 20050901

• Ci-Rga, a gene encoding an MtN3/saliva family transmembrane protein, is essential for tissue differentiation during embryogenesis of the ascidian Ciona intestinalis.

  Differentiation; research in biological diversity 20050901

• Influence of osmolytes on inactivation and aggregation of muscle glycogen phosphorylase b by guanidine hydrochloride. Stimulation of protein aggregation under crowding conditions.

  Biochemistry. Biokhimiia 20050901

• Three-component synthesis of polysubstituted homoproline analogs.

  Molecules (Basel, Switzerland) 20050831

• JLP associates with kinesin light chain 1 through a novel leucine zipper-like domain.

  The Journal of biological chemistry 20050826

• Identification of conserved prolyl residue important for transport activity and the substrate specificity range of yeast plasma membrane Na+/H+ antiporters.

  The Journal of biological chemistry 20050826

• Novel 3-amino-2-hydroxy acids containing protease inhibitors. Part 1: Synthesis and kinetic characterization as aminopeptidase P inhibitors.

  Bioorganic & medicinal chemistry 20050815

• Identification of S-hydroxylysyl-methionine as the covalent cross-link of the noncollagenous (NC1) hexamer of the alpha1alpha1alpha2 collagen IV network: a role for the post-translational modification of lysine 211 to hydroxylysine 211 in hexamer assembly.

  The Journal of biological chemistry 20050812

• Epitope mapping of monoclonal antibody to integrin alphaL beta2 hybrid domain suggests different requirements of affinity states for intercellular adhesion molecules (ICAM)-1 and ICAM-3 binding.

  The Journal of biological chemistry 20050812

• Designer antibacterial peptides kill fluoroquinolone-resistant clinical isolates.

  Journal of medicinal chemistry 20050811

• UV-resonance raman thermal unfolding study of Trp-cage shows that it is not a simple two-state miniprotein.

  Journal of the American Chemical Society 20050810

• Asymmetric aza-[2,3]-Wittig sigmatropic rearrangements: chiral auxiliary control and formal asymmetric synthesis of (2S, 3R, 4R)-4-hydroxy-3-methylproline and (-)-kainic acid.

  Organic & biomolecular chemistry 20050807

• Direct catalytic enantioselective aza-Diels-Alder reactions.

  Angewandte Chemie (International ed. in English) 20050805

• Preparation of de novo globular proteins based on proline dendrimers.

  The Journal of organic chemistry 20050805

• Locked conformations for proline pyrrolidine ring: synthesis and conformational analysis of cis- and trans-4-tert-butylprolines.

  The Journal of organic chemistry 20050805

• Highly enantioselective synthesis of fluorinated gamma-amino alcohols through proline-catalyzed cross-Mannich reaction.

  Organic letters 20050804

• Proximity-induced catalysis by the protein kinase ERK2.

  Journal of the American Chemical Society 20050803

• Synthesis and utilization of 13C and 15N backbone-labeled proline: NMR study of synthesized oxytocin with backbone-labeled C-terminal tripeptide amide.

  Amino acids 20050801

• HIV-1 Tat protein-induced VCAM-1 expression in human pulmonary artery endothelial cells and its signaling.

  American journal of physiology. Lung cellular and molecular physiology 20050801

• Copper(II) complexes with chicken prion repeats: influence of proline and tyrosine residues on the coordination features.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20050801

• Novel Src homology 3 domain-binding motifs identified from proteomic screen of a Pro-rich region.

  Molecular & cellular proteomics : MCP 20050801

• The effect of preoperative radiotherapy on systemic collagen deposition and postoperative infective complications in rectal cancer patients.

  Diseases of the colon and rectum 20050801

• Regeneration of cryoresistance of in vitro rumen ciliate cultures.

  Cryobiology 20050801

• Relationship between temporary inhibition and structure of disulfide-linkage analogs of marinostatin, a natural ester-linked protein protease inhibitor.

  The journal of peptide research : official journal of the American Peptide Society 20050801

• Human immunodeficiency virus type 1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in neuroblastoma cells through a nuclear factor-kappaB and activating protein-1 mediated mechanism.

  Journal of neurochemistry 20050801

• A novel desmin R355P mutation causes cardiac and skeletal myopathy.

  Neuromuscular disorders : NMD 20050801

• Synergistic effect of hypoxia and TNF-alpha on production of PAI-1 in human proximal renal tubular cells.

  Kidney international 20050801

• A concept of dietary dipeptides: a step to resolve the problem of amino acid availability in the early life of vertebrates.

  The Journal of experimental biology 20050801

• Comparative study on the changes in photosynthetic activity of the homoiochlorophyllous desiccation-tolerant Haberlea rhodopensis and desiccation-sensitive spinach leaves during desiccation and rehydration.

  Photosynthesis research 20050801

• DL-Proline.

  Acta crystallographica. Section C, Crystal structure communications 20050801

• Repetitive interactions observed in the crystal structure of a collagen-model peptide, [(Pro-Pro-Gly)9]3.

  Journal of biochemistry 20050801

• Ornithine alpha-ketoglutarate metabolism in the healthy rat in the postabsorptive state.

  Metabolism: clinical and experimental 20050801

• Influence of the C161T but not Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma on colorectal cancer in an Indian population.

  Cancer science 20050801

• [Osmotica accumulation and its role in osmotic adjustment in Thellungiella halophila under salt stress].

  Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20050801

• [Effects of cold-hardening on freezing tolerance and antioxidant enzyme activities in plantlets of Saussurea laniceps Hand.-Mazz].

  Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20050801

• Modulation of nitrate reductase activity in rice seedlings under aluminium toxicity and water stress: role of osmolytes as enzyme protectant.

  Journal of plant physiology 20050801

• FBI-1 enhances transcription of the nuclear factor-kappaB (NF-kappaB)-responsive E-selectin gene by nuclear localization of the p65 subunit of NF-kappaB.

  The Journal of biological chemistry 20050729

• Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60.

  The Journal of biological chemistry 20050729

• The 1.49 A resolution crystal structure of PsbQ from photosystem II of Spinacia oleracea reveals a PPII structure in the N-terminal region.

  Journal of molecular biology 20050729

• Dicarboxylic acid azacycle l-prolyl-pyrrolidine amides as prolyl oligopeptidase inhibitors and three-dimensional quantitative structure-activity relationship of the enzyme-inhibitor interactions.

  Journal of medicinal chemistry 20050728

• Discovery and preclinical profile of Saxagliptin (BMS-477118): a highly potent, long-acting, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

  Journal of medicinal chemistry 20050728

• Restricted variable residues in the C-terminal segment of HIV-1 V3 loop regulate the molecular anatomy of CCR5 utilization.

  Journal of molecular biology 20050722

• Proline-based N-oxides as readily available and modular chiral catalysts. Enantioselective reactions of allyltrichlorosilane with aldehydes.

  Organic letters 20050721

• Structure-activity studies with high-affinity inhibitors of pyroglutamyl-peptidase II.

  The Biochemical journal 20050715

• Interactive sites in the MyD88 Toll/interleukin (IL) 1 receptor domain responsible for coupling to the IL1beta signaling pathway.

  The Journal of biological chemistry 20050715

• The Pro335 --> Leu polymorphism of type 3 inositol 1,4,5-trisphosphate receptor found in mouse inbred lines results in functional change.

  The Journal of biological chemistry 20050715

• Mutational and structural analyses of the hinge region of membrane type 1-matrix metalloproteinase and enzyme processing.

  The Journal of biological chemistry 20050715

• RGD mounted on an L-proline scaffold.

  Bioorganic & medicinal chemistry letters 20050715

• Fine tuning the structure of the Cu2+ complex with the prion protein chicken repeat by proline isomerization.

  Chemical communications (Cambridge, England) 20050714

• Single peptide bonds exhibit poly(pro)II ('random coil') circular dichroism spectra.

  Journal of the American Chemical Society 20050713

• No association of breast cancer risk with integrin beta3 (ITGB3) Leu33Pro genotype.

  British journal of cancer 20050711

• Direct, facile aldehyde and ketone alpha-selenenylation reactions promoted by L-prolinamide and pyrrolidine sulfonamide organocatalysts.

  The Journal of organic chemistry 20050708

• Cell-penetrating cis-gamma-amino-l-proline-derived peptides.

  Journal of the American Chemical Society 20050706

• The conformational flexibility of the antibiotic virginiamycin M(1).

  European biophysics journal : EBJ 20050701

• Preliminary crystallographic analysis of the Cks protein p13(suc1P90AP92A) from Schizosacharromyces pombe.

  European biophysics journal : EBJ 20050701

• The role of protein-tyrosine phosphatase 1B in integrin signaling.

  The Journal of biological chemistry 20050701

• Ternary copper(II) complexes with N-carboxymethyl-l-prolinato(2-) ion and imidazole or creatinine: a comparative study of the interligand interactions influencing the molecular recognition and stability.

  Journal of inorganic biochemistry 20050701

• Involvement of the NMDA receptor, NO-cyclic GMP and nuclear factor K-beta in an animal model of repeated trauma.

  Human psychopharmacology 20050701

• Effects of free proline accumulation in petunias under drought stress.

  Journal of experimental botany 20050701

• Aromatic-aromatic and proline-aromatic interactions in endomorphin-1 and endomorphin-2.

  European journal of medicinal chemistry 20050701

• Crystal structure of methylenetetrahydromethanopterin reductase (Mer) in complex with coenzyme F420: Architecture of the F420/FMN binding site of enzymes within the nonprolyl cis-peptide containing bacterial luciferase family.

  Protein science : a publication of the Protein Society 20050701

• Prolyl isomerization as a molecular timer in phage infection.

  Nature structural & molecular biology 20050701

• Eukaryotic transcription factors as direct nutrient sensors.

  Trends in biochemical sciences 20050701

• Proline mutations induce negative-dosage effects on uptake velocity of the dopamine transporter.

  Journal of neurochemistry 20050701

• Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: importance of proline spacing and glutamine deamidation.

  Journal of immunology (Baltimore, Md. : 1950) 20050701

• The CD3epsilon proline-rich sequence, and its interaction with Nck, is not required for T cell development and function.

  Journal of immunology (Baltimore, Md. : 1950) 20050701

• Inverse effects of the PPAR(gamma)2 Pro12Ala polymorphism on measures of adiposity over 15 years in African Americans and whites. The CARDIA study.

  Metabolism: clinical and experimental 20050701

• Expression of CX3C chemokine, fractalkine, and its receptor CX3CR1 in experimental autoimmune anterior uveitis.

  Molecular vision 20050701

• Resonance assignments for mouse S100A13.

  Journal of biomolecular NMR 20050701

• [Determination of amino acids in Isatis indigotica Fort by reversed-phase high performance liquid chromatography with pre-column derivatization].

  Se pu = Chinese journal of chromatography 20050701

• [Determination of amino acids in fu fang banlangen granulae by a pre-column derivatization RP-HPLC method].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050701

• 'Five at one stroke': proline and small peptides in the stereoselective de novo synthesis and enantiotopic functionalization of carbohydrates.

  Chemistry & biodiversity 20050701

• N-benzyloxycarbonyl-L-proline: an in vitro and in vivo inhibitor of prolidase.

  Biochimica et biophysica acta 20050630

• A highly efficient organocatalyst for direct aldol reactions of ketones with aldehydes [corrected].

  Journal of the American Chemical Society 20050629

• Brain microvessel endothelial cell responses to tumor necrosis factor-alpha involve a nuclear factor kappa B (NF-kappaB) signal transduction pathway.

  Brain research 20050628

• Characterization of disulfide bonds in human nucleoside triphosphate diphosphohydrolase 3 (NTPDase3): implications for NTPDase structural modeling.

  Biochemistry 20050628

• Characterization of a bifunctional PutA homologue from Bradyrhizobium japonicum and identification of an active site residue that modulates proline reduction of the flavin adenine dinucleotide cofactor.

  Biochemistry 20050628

• Dihydroxyacetone in amino acid catalyzed Mannich-type reactions.

  Angewandte Chemie (International ed. in English) 20050627

• Amino acid promoted CuI-catalyzed C-N bond formation between aryl halides and amines or N-containing heterocycles.

  The Journal of organic chemistry 20050624

• Relating kinetic rates and local energetic roughness by accelerated molecular-dynamics simulations.

  The Journal of chemical physics 20050622

• Kinetics of Src homology 3 domain association with the proline-rich domain of dynamins: specificity, occlusion, and the effects of phosphorylation.

  The Journal of biological chemistry 20050617

• Antioxidant properties of malt model systems.

  Journal of agricultural and food chemistry 20050615

• Depressor responses to L-proline microinjected into the rat ventrolateral medulla are mediated by ionotropic excitatory amino acid receptors.

  Autonomic neuroscience : basic & clinical 20050615

• Cloning and functional study of porcine parotid hormone, a novel proline-rich protein.

  The Journal of biological chemistry 20050610

• The Pro33 isoform of integrin beta3 enhances outside-in signaling in human platelets by regulating the activation of serine/threonine phosphatases.

  The Journal of biological chemistry 20050610

• Main chain hydrogen bond interactions in the binding of proline-rich gluten peptides to the celiac disease-associated HLA-DQ2 molecule.

  The Journal of biological chemistry 20050610

• Enantioselective double C-H activation of dihydronaphthalenes.

  Organic letters 20050609

• Proline editing: a divergent strategy for the synthesis of conformationally diverse peptides.

  Organic letters 20050609

• Correlation of structural elements and infectivity of the HET-s prion.

  Nature 20050609

• Autochelation in dipeptide boronic acids: pH-dependent structures and equilibria of Asp-boroPro and His-boroPro by NMR spectroscopy.

  Journal of the American Chemical Society 20050608

• Signaling pathways involved in tumor necrosis factor alpha-induced upregulation of the taurine transporter in Caco-2 cells.

  FEBS letters 20050606

• Proline-rich tyrosine kinase 2 (Pyk2) mediates vascular endothelial-cadherin-based cell-cell adhesion by regulating beta-catenin tyrosine phosphorylation.

  The Journal of biological chemistry 20050603

• ArgBP2gamma interacts with Akt and p21-activated kinase-1 and promotes cell survival.

  The Journal of biological chemistry 20050603

• Oxysterols inhibit phosphatidylcholine synthesis via ERK docking and phosphorylation of CTP:phosphocholine cytidylyltransferase.

  The Journal of biological chemistry 20050603

• Design, synthesis, and evaluation of proline based melanocortin receptor ligands.

  Bioorganic & medicinal chemistry letters 20050602

• Arginine synthesis does not occur during first-pass hepatic metabolism in the neonatal piglet.

  American journal of physiology. Endocrinology and metabolism 20050601

• The Leu7Pro polymorphism of preproNPY is associated with decreased insulin secretion, delayed ghrelin suppression, and increased cardiovascular responsiveness to norepinephrine during oral glucose tolerance test.

  The Journal of clinical endocrinology and metabolism 20050601

• Analysis of separate and combined effects of common variation in KCNJ11 and PPARG on risk of type 2 diabetes.

  The Journal of clinical endocrinology and metabolism 20050601

• Abiotic metal stress enhances diosgenin yield in Dioscorea bulbifera L. cultures.

  Plant cell reports 20050601

• Physiological role for the cochaperone FKBP52 in androgen receptor signaling.

  Molecular endocrinology (Baltimore, Md.) 20050601

• Liddle syndrome caused by P616R mutation of the epithelial sodium channel beta subunit.

  Pediatric nephrology (Berlin, Germany) 20050601

• Biosynthetic precursors of fungal pyrrolizidines, the loline alkaloids.

  Chembiochem : a European journal of chemical biology 20050601

• Mutation of single murine acetylcholine receptor subunits reveals differential contribution of P121 to acetylcholine binding and channel opening.

  Pflugers Archiv : European journal of physiology 20050601

• Human bone collagen synthesis is a rapid, nutritionally modulated process.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050601

• Combined solid-phase/solution synthesis of large ribonuclease A C-terminal peptides containing a non-natural proline analog.

  The journal of peptide research : official journal of the American Peptide Society 20050601

• Fatty acyl moieties: improving Pro-rich peptide uptake inside HeLa cells.

  The journal of peptide research : official journal of the American Peptide Society 20050601

• Root border-like cells of Arabidopsis. Microscopical characterization and role in the interaction with rhizobacteria.

  Plant physiology 20050601

• Mutation analysis of COL9A3, a gene highly expressed in the cochlea, in hearing loss patients.

  Auris, nasus, larynx 20050601

• Hemangioblastomas of central nervous system: molecular genetic analysis and clinical management.

  Neurosurgery 20050601

• Experimental determination of proline hydroxylation and hydroxyproline arabinogalactosylation motifs in secretory proteins.

  The Plant journal : for cell and molecular biology 20050601

• Effects of luminal deoxynivalenol and L-proline on electrophysiological parameters in the jejunums of laying hens.

  Poultry science 20050601

• [Inhibitory effect of daunorubicin enhanced by PDTC on drug-resistant leukemic cells in vitro].

  Zhongguo shi yan xue ye xue za zhi 20050601

• Engineering of yeast Put4 permease and its application to lager yeast for efficient proline assimilation.

  Bioscience, biotechnology, and biochemistry 20050601

• Melanin potentiates kanamycin-induced inhibition of collagen biosynthesis in human skin fibroblasts.

  Die Pharmazie 20050601

• Estradiol prevents neural tau hyperphosphorylation characteristic of Alzheimer's disease.

  Annals of the New York Academy of Sciences 20050601

• [Effects of anther--pretreatments on the survival percentage of isolated microspores of maize].

  Shi yan sheng wu xue bao 20050601

• Aspartyl-tRNA synthetase requires a conserved proline in the anticodon-binding loop for tRNA(Asn) recognition in vivo.

  The Journal of biological chemistry 20050527

• The crystal structure of the collagen-like polypeptide (glycyl-4(R)-hydroxyprolyl-4(R)-hydroxyprolyl)9 at 1.55 A resolution shows up-puckering of the proline ring in the Xaa position.

  The Journal of biological chemistry 20050527

• Probing enantiospecific interactions between proline and an l-glutathione self-assembled monolayer by modulation excitation ATR-IR spectroscopy.

  The journal of physical chemistry. B 20050526

• Effects of amino acid additions on ammonium stressed CHO cells.

  Journal of biotechnology 20050525

• Structural difference between group I and group II cobra cardiotoxins: X-ray, NMR, and CD analysis of the effect of cis-proline conformation on three-fingered toxins.

  Biochemistry 20050524

• Diastereoselective annulation of 4-hydroxypyran-2H-ones with enantiopure 2,3-dideoxy-alpha,beta-unsaturated sugar aldehydes derived from respective glycals.

  Carbohydrate research 20050523

• Prebiotic carbohydrate synthesis: zinc-proline catalyzes direct aqueous aldol reactions of alpha-hydroxy aldehydes and ketones.

  Organic & biomolecular chemistry 20050521

• Re: Integrin beta3 Leu33Pro homozygosity and risk of cancer.

  Journal of the National Cancer Institute 20050518

• Site-directed mutagenesis of proline 94 to alanine in amicyanin converts a true electron transfer reaction into one that is kinetically coupled.

  Biochemistry 20050517

• Aggregation of a slow-folding mutant of a beta-clam protein proceeds through a monomeric nucleus.

  Biochemistry 20050517

• Pathogenic effects of a novel heterozygous R350P desmin mutation on the assembly of desmin intermediate filaments in vivo and in vitro.

  Human molecular genetics 20050515

• Preparation and evaluation of proline-based chiral columns.

  Analytical chemistry 20050515

• Identification and functional characterization of a novel low affinity aromatic-preferring amino acid transporter (arpAT). One of the few proteins silenced during primate evolution.

  The Journal of biological chemistry 20050513

• Design of an axially chiral amino acid with a binaphthyl backbone as an organocatalyst for a direct asymmetric aldol reaction.

  Angewandte Chemie (International ed. in English) 20050513

• Natural mutations in a 2'-5' oligoadenylate synthetase transgene revealed residues essential for enzyme activity.

  Biochemistry 20050510

• Hierarchical phosphorylation of the TNF-alpha receptor, TNF-R1, by p42Mapk/Erk at basic Pro-directed kinase sites.

  Biochemistry 20050510

• Structural requirements of the unique disulphide bond and the proline-rich motif within the alpha4-alpha5 loop for larvicidal activity of the Bacillus thuringiensis Cry4Aa delta-endotoxin.

  Biochemical and biophysical research communications 20050506

• Recognition of proline-rich motifs by protein-protein-interaction domains.

  Angewandte Chemie (International ed. in English) 20050506

• Hyperprolinemia is a risk factor for schizoaffective disorder.

  Molecular psychiatry 20050501

• Bulgecin A: a novel inhibitor of binuclear metallo-beta-lactamases.

  The Biochemical journal 20050501

• Paclitaxel probably enhances cytotoxicity of natural killer cells against breast carcinoma cells by increasing perforin production.

  Cancer immunology, immunotherapy : CII 20050501

• Alcohol intake modulates the genetic association between HDL cholesterol and the PPARgamma2 Pro12Ala polymorphism.

  Journal of lipid research 20050501

• Preferred stereoselective transport of the D-isomer of cis-4-[18F]fluoro-proline at the blood-brain barrier.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050501

• The alpha-helical propensity of the cytoplasmic domain of phospholamban: a molecular dynamics simulation of the effect of phosphorylation and mutation.

  Biophysical journal 20050501

• Effect of hyperprolinemia on acetylcholinesterase and butyrylcholinesterase activities in rat.

  Amino acids 20050501

• Synthesis of alveolar bone Sharpey's fibers during experimental tooth movement in the rat.

  The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 20050501

• Tris(2,2'-bipyridyl)ruthenium(II)-zirconia-Nafion composite films applied as solid-state electrochemiluminescence detector for capillary electrophoresis.

  Electrophoresis 20050501

• Deletion of the proline-rich region of TonB disrupts formation of a 2:1 complex with FhuA, an outer membrane receptor of Escherichia coli.

  Protein science : a publication of the Protein Society 20050501

• Protective effect of antioxidants on brain oxidative damage caused by proline administration.

  Neuroscience research 20050501

• Under the influence of phi and psi.

  Journal of peptide science : an official publication of the European Peptide Society 20050501

• Ascorbate depletion: a critical step in nickel carcinogenesis?

  Environmental health perspectives 20050501

• Treatment of cartilage with beta-aminopropionitrile accelerates subsequent collagen maturation and modulates integrative repair.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20050501

• A novel threonine to proline mutation in the helix termination motif of keratin 1 in epidermolytic hyperkeratosis with severe palmoplantar hyperkeratosis and contractures of the digits.

  The British journal of dermatology 20050501

• CYP3A43 Pro(340)Ala polymorphism and prostate cancer risk in African Americans and Caucasians.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050501

• Conformationally constrained PNA analogues: structural evolution toward DNA/RNA binding selectivity.

  Accounts of chemical research 20050501

• Conformational analysis of the C-terminal Gly-Leu-Met-NH2 tripeptide of substance P bound to the NK-1 receptor.

  Chemistry & biology 20050501

• FGFR3 P250R mutation increases the risk of reoperation in apparent 'nonsyndromic' coronal craniosynostosis.

  The Journal of craniofacial surgery 20050501

• Effect of several growth factors on canine flexor tendon fibroblast proliferation and collagen synthesis in vitro.

  The Journal of hand surgery 20050501

• Leu7Pro polymorphism in the neuropeptide Y (NPY) gene is associated with impaired glucose tolerance and type 2 diabetes in Swedish men.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20050501

• Inhibiton of NF-kappaB activation during ischemia reduces hepatic ischemia/reperfusion injury in rats.

  The Journal of toxicological sciences 20050501

• [Role of nitric oxide-nuclear factor kappaB signal pathway in functional expression of T lymphocytes from asthmatic patients].

  Zhonghua nei ke za zhi 20050501

• Regulation of CD147 cell surface expression: involvement of the proline residue in the CD147 transmembrane domain.

  The Journal of biological chemistry 20050429

• A mitochondrial NADH-dependent fumarate reductase involved in the production of succinate excreted by procyclic Trypanosoma brucei.

  The Journal of biological chemistry 20050429

• Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3.

  Journal of molecular biology 20050429

• Nuclear magnetic resonance characterization of the refolding intermediate of beta2-microglobulin trapped by non-native prolyl peptide bond.

  Journal of molecular biology 20050429

• An enantioselective NMR shift reagent for cationic aromatics.

  Organic letters 20050428

• A fluorous chiral dirhodium(II) complex as a recyclable asymmetric catalyst.

  Organic letters 20050428

• Indolactam-V is involved in the CH/pi interaction with Pro-11 of the PKCdelta C1B domain: application for the structural optimization of the PKCdelta ligand.

  Journal of the American Chemical Society 20050427

• Different effects of 4-hydroxyproline and 4-fluoroproline on the stability of collagen triple helix.

  Biochemistry 20050426

• Global transcriptional programs reveal a carbon source foraging strategy by Escherichia coli.

  The Journal of biological chemistry 20050422

• Succinct synthesis of beta-amino acids via chiral isoxazolines.

  Journal of the American Chemical Society 20050420

• Molecular characterization of the human Calpha-formylglycine-generating enzyme.

  The Journal of biological chemistry 20050415

• Cholesteryl ester transfer protein variants have differential stability but uniform inhibition by torcetrapib.

  The Journal of biological chemistry 20050415

• Crystal structure of N-acetylornithine transcarbamylase from Xanthomonas campestris: a novel enzyme in a new arginine biosynthetic pathway found in several eubacteria.

  The Journal of biological chemistry 20050415

• A human congenital myasthenia-causing mutation (epsilon L78P) of the muscle nicotinic acetylcholine receptor with unusual single channel properties.

  The Journal of physiology 20050415

• Characterization of two non-testis-specific CABYR variants that bind to GSK3beta with a proline-rich extensin-like domain.

  Biochemical and biophysical research communications 20050415

• Parallel solid-phase synthesis and characterization of new sulfonamide and carboxamide proline derivatives as potential CNS agents.

  Bioorganic & medicinal chemistry 20050415

• IR study of cross-strand coupling in a beta-hairpin peptide using isotopic labels.

  Journal of the American Chemical Society 20050413

• Amino acids--valuable organocatalysts in carbohydrate synthesis.

  Angewandte Chemie (International ed. in English) 20050408

• 9-hydroxyazafluorenes and their use in thrombin inhibitors.

  Journal of medicinal chemistry 20050407

• Polyamine synthesis from proline in the developing porcine placenta.

  Biology of reproduction 20050401

• New functions for parts of the Krebs cycle in procyclic Trypanosoma brucei, a cycle not operating as a cycle.

  The Journal of biological chemistry 20050401

• Assembly of lipoprotein particles containing apolipoprotein-B: structural model for the nascent lipoprotein particle.

  Biophysical journal 20050401

• A novel epithelial sodium channel beta-subunit mutation associated with hypertensive Liddle syndrome.

  Pediatric nephrology (Berlin, Germany) 20050401

• Aldosterone activates vascular p38MAP kinase and NADPH oxidase via c-Src.

  Hypertension (Dallas, Tex. : 1979) 20050401

• T-cell recognition of HLA-DQ2-bound gluten peptides can be influenced by an N-terminal proline at p-1.

  Immunogenetics 20050401

• C-terminal sequencing by mass spectrometry: application to gelatine-derived proline-rich peptides.

  Proteomics 20050401

• Intriguing conformation changes associated with the trans/cis isomerization of a prolyl residue in the active site of the DsbA C33A mutant.

  Journal of molecular biology 20050401

• Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein.

  Experimental neurology 20050401

• Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate.

  Experimental neurology 20050401

• Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease.

  Neurobiology of disease 20050401

• The flexibility in the proline ring couples to the protein backbone.

  Protein science : a publication of the Protein Society 20050401

• Identification of a bacterial factor required for actin-based motility of Burkholderia pseudomallei.

  Molecular microbiology 20050401

• Synthesis of aryl sulfones via L-proline-promoted CuI-catalyzed coupling reaction of aryl halides with sulfinic acid salts.

  The Journal of organic chemistry 20050401

• An autosomal recessive limb girdle muscular dystrophy (LGMD2) with mild mental retardation is allelic to Walker-Warburg syndrome (WWS) caused by a mutation in the POMT1 gene.

  Neuromuscular disorders : NMD 20050401

• A novel missense mutation in the Connexin 26 gene associated with autosomal recessive sensorineural deafness.

  Hearing research 20050401

• The p53 codon 72 proline allele is associated with p53 gene mutations in non-small cell lung cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050401

• Inhibition of integrative cartilage repair by proteoglycan 4 in synovial fluid.

  Arthritis and rheumatism 20050401

• Targeted delivery to PEPT1-overexpressing cells: acidic, basic, and secondary floxuridine amino acid ester prodrugs.

  Molecular cancer therapeutics 20050401

• A severe case of pachyonychia congenita type I due to a novel proline mutation in keratin 6a.

  The British journal of dermatology 20050401

• Absence of Pro475Ser polymorphism in ADAMTS-13 in Caucasians.

  Journal of thrombosis and haemostasis : JTH 20050401

• 17alpha-hydroxylase/17,20-Lyase deficiency due to novel compound heterozygote mutations: treatment for tall stature in a female with male pseudohermaphroditism and spontaneous puberty in her affected sister.

  Journal of pediatric endocrinology & metabolism : JPEM 20050401

• Effect of proline and K+ on the stimulation of cellular activities in Escherichia coli K-12 under high salinity.

  Bioscience, biotechnology, and biochemistry 20050401

• Accumulation of extracellular proteins bearing unique proline-rich motifs in intercellular spaces of the legume nodule parenchyma.

  Protoplasma 20050401

• A set of HA-detected experiments for measuring scalar and residual dipolar couplings.

  Journal of biomolecular NMR 20050401

• Backbone resonance assignment of the homodimeric, 35 kDa chaperone CesT from enteropathogenic Escherichia coli.

  Journal of biomolecular NMR 20050401

• C-terminal Pro-Gly-Pro tripeptide in contrast to full-length neuropeptide semax exhibits no neuroprotective effect in experimental cerebral ischemia.

  Bulletin of experimental biology and medicine 20050401

• Proline metabolism in procyclic Trypanosoma brucei is down-regulated in the presence of glucose.

  The Journal of biological chemistry 20050325

• Structure of the adaptor protein p14 reveals a profilin-like fold with distinct function.

  Journal of molecular biology 20050325

• First principle computational study on the full conformational space of L-proline diamides.

  The journal of physical chemistry. A 20050324

• Insect repellent/antifeedant activity of 2,4-methanoproline and derivatives against a leaf- and seed-feeding pest insect.

  Journal of agricultural and food chemistry 20050323

• Total synthesis of brasoside and littoralisone.

  Journal of the American Chemical Society 20050323

• Behavior of diphtheria toxin T domain containing substitutions that block normal membrane insertion at Pro345 and Leu307: control of deep membrane insertion and coupling between deep insertion of hydrophobic subdomains.

  Biochemistry 20050322

• Kinetic resolution of sec-alcohols using a new class of readily assembled (S)-proline-derived 4-(pyrrolidino)-pyridine analogues.

  Organic & biomolecular chemistry 20050321

• Distinct domains control the addressing and the insertion of Bax into mitochondria.

  The Journal of biological chemistry 20050318

• CD80 binding polyproline helical peptide inhibits T cell activation.

  The Journal of biological chemistry 20050318

• Mitotic phosphorylation rescues Abl from F-actin-mediated inhibition.

  The Journal of biological chemistry 20050318

• Exceptional disfavor for proline at the P + 1 position among AGC and CAMK kinases establishes reciprocal specificity between them and the proline-directed kinases.

  The Journal of biological chemistry 20050318

• Cu(I)-catalyzed enantioselective [3 + 2] cycloaddition reaction of 1-alkylallenylsilane with alpha-imino ester: asymmetric synthesis of dehydroproline derivatives.

  Organic letters 20050317

• Increased structural complexity leads to higher activity: peptides as efficient and versatile catalysts for asymmetric aldol reactions.

  Organic letters 20050317

• Effect of proline and glycine residues on dynamics and barriers of loop formation in polypeptide chains.

  Journal of the American Chemical Society 20050316

• Molecular cloning of the mouse IMINO system: an Na+- and Cl--dependent proline transporter.

  The Biochemical journal 20050315

• A novel tetraspanin fusion protein, peripherin-2, requires a region upstream of the fusion domain for activity.

  The Journal of biological chemistry 20050311

• Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino.

  The Journal of biological chemistry 20050311

• Structures of cationized proline analogues: evidence for the zwitterionic form.

  The journal of physical chemistry. A 20050310

• Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities.

  The EMBO journal 20050309

• A photoinducible beta-hairpin.

  Journal of the American Chemical Society 20050309

• Two novel types of O-glycans on the mugwort pollen allergen Art v 1 and their role in antibody binding.

  The Journal of biological chemistry 20050304

• Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex.

  The Journal of biological chemistry 20050304

• T cell receptor-induced activation of phospholipase C-gamma1 depends on a sequence-independent function of the P-I region of SLP-76.

  The Journal of biological chemistry 20050304

• Novel approach to 5-substituted proline derivatives using a silver-catalyzed cyclization as the key step.

  The Journal of organic chemistry 20050304

• A synthetic human proline-rich-polypeptide enhances hydroxyl radical generation and fails to protect dopaminergic neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced toxicity in mice.

  Neuroscience letters 20050303

• Intraresidue distribution of energy in proteins.

  The journal of physical chemistry. B 20050303

• The PPAR{gamma} Pro12Ala polymorphism and risk for incident sporadic colorectal adenomas.

  Carcinogenesis 20050301

• Functional consequences of PRODH missense mutations.

  American journal of human genetics 20050301

• A gene encoding a protein with a proline-rich domain (MtPPRD1), revealed by suppressive subtractive hybridization (SSH), is specifically expressed in the Medicago truncatula embryo axis during germination.

  Journal of experimental botany 20050301

• Pioglitazone inhibits cell growth and reduces matrix production in human kidney fibroblasts.

  Journal of the American Society of Nephrology : JASN 20050301

• Endurance exercise training in orthostatic intolerance: a randomized, controlled trial.

  Hypertension (Dallas, Tex. : 1979) 20050301

• In vivo antitumor effect of ascorbic acid, lysine, proline and green tea extract on human colon cancer cell HCT 116 xenografts in nude mice: evaluation of tumor growth and immunohistochemistry.

  Oncology reports 20050301

• Mutagenesis studies of conserved proline residues of human P2X receptors for ATP indicate that proline 272 contributes to channel function.

  Journal of neurochemistry 20050301

• Multiple periods of functional ocular dominance plasticity in mouse visual cortex.

  Nature neuroscience 20050301

• Synthesis and biological evaluation of new GABA-uptake inhibitors derived from proline and from pyrrolidine-2-acetic acid.

  European journal of medicinal chemistry 20050301

• Apoptosis-deficient Pro allele of p53 gene is associated with the resistance of psoriasis to the UV-based therapy.

  Journal of dermatological science 20050301

• PPAR-gamma activation inhibits angiogenesis by blocking ELR+CXC chemokine production in non-small cell lung cancer.

  Neoplasia (New York, N.Y.) 20050301

• 1H, 13C, and 15N resonance assignments of SAP18.

  Journal of biomolecular NMR 20050301

• Chronic hyperprolinemia provokes a memory deficit in the Morris water maze task.

  Metabolic brain disease 20050301

• Changed course of cytotoxic reaction as a result of modification of target cell membrane.

  Bulletin of experimental biology and medicine 20050301

• Simultaneous determination of amphetamine and methamphetamine enantiomers in urine by simultaneous liquid-liquid extraction and diastereomeric derivatization followed by gas chromatographic-isotope dilution mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225

• Mechanisms mediating the biologic activity of synthetic proline, glycine, and hydroxyproline polypeptides in human neutrophils.

  Mediators of inflammation 20050224

• Protein heterodimerization through ligand-bridged multivalent pre-organization: enhancing ligand binding toward both protein targets.

  Journal of the American Chemical Society 20050223

• Amyloid beta-protein: monomer structure and early aggregation states of Abeta42 and its Pro19 alloform.

  Journal of the American Chemical Society 20050223

• Cytochrome b5 reductase: role of the si-face residues, proline 92 and tyrosine 93, in structure and catalysis.

  Biochemistry 20050222

• Decrease in protein solubility and cataract formation caused by the Pro23 to Thr mutation in human gamma D-crystallin.

  Biochemistry 20050222

• Roles of conserved proline and glycosyltransferase motifs of EmbC in biosynthesis of lipoarabinomannan.

  The Journal of biological chemistry 20050218

• The putative malate/lactate dehydrogenase from Pseudomonas putida is an NADPH-dependent delta1-piperideine-2-carboxylate/delta1-pyrroline-2-carboxylate reductase involved in the catabolism of D-lysine and D-proline.

  The Journal of biological chemistry 20050218

• Direct amino acid catalyzed asymmetric synthesis of polyketide sugars.

  Angewandte Chemie (International ed. in English) 20050218

• The impact of pyrrolidine hydroxylation on the conformation of proline-containing peptides.

  The Journal of organic chemistry 20050218

• Incorporation of pseudoproline derivatives allows the facile synthesis of human IAPP, a highly amyloidogenic and aggregation-prone polypeptide.

  Organic letters 20050217

• Phosphorylation effects on cis/trans isomerization and the backbone conformation of serine-proline motifs: accelerated molecular dynamics analysis.

  Journal of the American Chemical Society 20050216

• The effect of the farnesyl protein transferase inhibitor SCH66336 on isoprenylation and signalling by the prostacyclin receptor.

  The Biochemical journal 20050215

• A proline-rich polypeptide complex and its nonapeptide fragment inhibit nitric oxide production induced in mice.

  Regulatory peptides 20050215

• The Smad3 linker region contains a transcriptional activation domain.

  The Biochemical journal 20050215

• Conservation of cis prolyl bonds in proteins during evolution.

  Proteins 20050215

• Peptide models XLV: conformational properties of N-formyl-L-methioninamide and its relevance to methionine in proteins.

  Proteins 20050215

• Modulation of 5-fluorouracil cytotoxicity through thymidylate synthase and NF-kappaB down-regulation and its application on the radiolabelled iododeoxyuridine therapy on human hepatoma cell.

  Biochemical pharmacology 20050215

• Substrate specificities of Escherichia coli thioesterase I/protease I/lysophospholipase L1 are governed by its switch loop movement.

  Biochemistry 20050215

• Conformational flexibility in crystal structures of human 11beta-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulation.

  The Journal of biological chemistry 20050211

• Destabilization of the transmembrane domain induces misfolding in a phenotypic mutant of cystic fibrosis transmembrane conductance regulator.

  The Journal of biological chemistry 20050211

• Induced fit of an epitope peptide to a monoclonal antibody probed with a novel parallel surface plasmon resonance assay.

  The Journal of biological chemistry 20050211

• Characterizing the sphingolipid signaling pathway that remediates defects associated with loss of the yeast amphiphysin-like orthologs, Rvs161p and Rvs167p.

  The Journal of biological chemistry 20050211

• Mapping the functional domains of the Golgi stacking factor GRASP65.

  The Journal of biological chemistry 20050211

• A region in the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+.

  The Journal of biological chemistry 20050211

• Modulation of age at onset of Huntington disease patients by variations in TP53 and human caspase activated DNase (hCAD) genes.

  Neuroscience letters 20050210

• In the quest for stable rescuing mutants of p53: computational mutagenesis of flexible loop L1.

  Biochemistry 20050208

• Direct interaction of a divergent CaM isoform and the transcription factor, MYB2, enhances salt tolerance in arabidopsis.

  The Journal of biological chemistry 20050204

• Protein sequence randomization: efficient estimation of protein stability using knowledge-based potentials.

  Journal of molecular biology 20050204

• Synthesis of 4-aryl-2-pyrrolidones and beta-aryl-gamma-amino-butyric acid (GABA) analogues by Heck arylation of 3-pyrrolines with arenediazonium tetrafluoroborates. Synthesis of (+/-)-rolipram on a multigram scale and chromatographic resolution by semipreparative chiral simulated moving bed chromatography.

  The Journal of organic chemistry 20050204

• P253R fibroblast growth factor receptor-2 mutation induces RUNX2 transcript variants and calvarial osteoblast differentiation.

  Journal of cellular physiology 20050201

• Mechanism of SHIP-mediated inhibition of insulin- and platelet-derived growth factor-stimulated mitogen-activated protein kinase activity in 3T3-L1 adipocytes.

  Molecular endocrinology (Baltimore, Md.) 20050201

• Issues in high-throughput comparative modelling: a case study using the ubiquitin E2 conjugating enzymes.

  Proteins 20050201

• A novel mutation of keratin 9 gene (R162P) in a Japanese family with epidermolytic palmoplantar keratoderma.

  Archives of dermatological research 20050201

• Conformation and activity of delta-lysin and its analogs.

  Peptides 20050201

• Microradiographic study on the effects of salivary proteins on in vitro demineralization of bovine enamel.

  Journal of oral rehabilitation 20050201

• Antitumor effect of nutrient synergy on human osteosarcoma cells U-2OS, MNNG-HOS and Ewing's sarcoma SK-ES.1.

  Oncology reports 20050201

• Peroxisome proliferator-activated receptor-gamma2 Pro12Ala and endothelial nitric oxide synthase-4a/b gene polymorphisms are not associated with hypertension in diabetes mellitus type 2.

  Journal of hypertension 20050201

• Direct asymmetric aldol reactions catalyzed by (4R)-4-(beta-Naphthalenyl)methoxy-(S)-proline.

  Chirality 20050201

• [Variation of betaine and proline contents in wheat seedlings under salt stress].

  Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20050201

• Specificity of odorant-evoked inhibition in lobster olfactory receptor neurons.

  Chemical senses 20050201

• Sequence tag scanning: a new explorative strategy for recognition of unexpected protein alterations by nanoelectrospray ionization-tandem mass spectrometry.

  Proteomics 20050201

• Association of micropenis with Pro185Ala polymorphism of the gene for aryl hydrocarbon receptor repressor involved in dioxin signaling.

  Endocrine journal 20050201

• Morphological and biochemical alterations of oomycete fish pathogen Saprolegnia parasitica as affected by salinity, ascorbic acid and their synergistic action.

  Mycopathologia 20050201

• [PPARgamma gene Pro12Ala polymorphism in diabetes mellitus].

  Nihon rinsho. Japanese journal of clinical medicine 20050201

• Identification of a neural cell specific variant of microtubule-associated protein 4.

  Cell structure and function 20050201

• [Homocysteine induces macrophage inflammatory protein-1alpha expression by activating NF-kappaB in THP-1 monocytes].

  Zhonghua bing li xue za zhi = Chinese journal of pathology 20050201

• [Construction of fused osmoregulation proBA gene from a salt-tolerant mutant of Bacillus subtilis and its influence on the osmotolerance of Escherichia coli].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20050201

• Endothelin-converting enzyme-1 inhibition and growth of human glioblastoma cells.

  Journal of medicinal chemistry 20050127

• Unique oxidation reaction of amides with pyridine-N-oxide catalyzed by ruthenium porphyrin: direct oxidative conversion of N-acyl-L-proline to N-acyl-L-glutamate.

  Journal of the American Chemical Society 20050126

• GABA shunt deficiencies and accumulation of reactive oxygen intermediates: insight from Arabidopsis mutants.

  FEBS letters 20050117

• Characterization of a second Arabidopsis thaliana prolyl 4-hydroxylase with distinct substrate specificity.

  The Journal of biological chemistry 20050114

• Proprotein convertase models based on the crystal structures of furin and kexin: explanation of their specificity.

  Journal of molecular biology 20050114

• Assembly of Acanthamoeba myosin-II minifilaments. Definition of C-terminal residues required to form coiled-coils, dimers, and octamers.

  Journal of molecular biology 20050114

• Homozygosity for Pro of p53 Arg72Pro as a potential risk factor for hepatocellular carcinoma in Chinese population.

  World journal of gastroenterology 20050114

• Predisposition to mouse thymic lymphomas in response to ionizing radiation depends on variant alleles encoding metal-responsive transcription factor-1 (Mtf-1).

  Oncogene 20050113

• Enantioselective organocatalytic hydride reduction.

  Journal of the American Chemical Society 20050112

• Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch.

  Biochemistry 20050111

• Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions.

  Organic & biomolecular chemistry 20050107

• A re-investigation of copper coordination in the octa-repeats region of the prion protein.

  Dalton transactions (Cambridge, England : 2003) 20050107

• Vibrational spectroscopy of a non-aromatic amino acid-based model peptide: identification of the gamma-turn motif of the peptide backbone.

  Physical chemistry chemical physics : PCCP 20050107

• Stereoselective synthesis of alpha,alpha'-biprolines.

  Organic letters 20050106

• Profibrotic influence of high glucose concentration on cardiac fibroblast functions: effects of losartan and vitamin E.

  American journal of physiology. Heart and circulatory physiology 20050101

• Conserved extracellular cysteine residues and cytoplasmic loop-loop interplay are required for functionality of the heptahelical MLO protein.

  The Biochemical journal 20050101

• Synthesis of fluorescent label, DBD-beta-proline, and the resolution efficiency for chiral amines by reversed-phase chromatography.

  Biomedical chromatography : BMC 20050101

• Liddle's syndrome caused by a novel mutation in the proline-rich PY motif of the epithelial sodium channel beta-subunit.

  The Journal of clinical endocrinology and metabolism 20050101

• The BIR domain of IAP-like protein 2 is conformationally unstable: implications for caspase inhibition.

  The Biochemical journal 20050101

• Delta1-pyrroline-5-carboxylate synthase deficiency: neurodegeneration, cataracts and connective tissue manifestations combined with hyperammonaemia and reduced ornithine, citrulline, arginine and proline.

  European journal of pediatrics 20050101

• PPAR-gamma2 Pro12Ala variant is associated with greater insulin sensitivity in childhood obesity.

  Pediatric research 20050101

• Folding Trp-cage to NMR resolution native structure using a coarse-grained protein model.

  Biophysical journal 20050101

• A case study of proline isomerization in cell signaling.

  Frontiers in bioscience : a journal and virtual library 20050101

• Substitution of proline 306 in the reverse transcriptase domain of hepatitis B virus regulates replication.

  The Journal of general virology 20050101

• A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors.

  Molecular pharmacology 20050101

• Adenosine kinase inhibitor attenuates the expression of inducible nitric oxide synthase in glial cells.

  Neuropharmacology 20050101

• Effect of osmolytes on the interaction of flavin adenine dinucleotide with muscle glycogen phosphorylase b.

  Biophysical chemistry 20050101

• Ab initio conformational study of N-acetyl-L-proline-N',N'-dimethylamide: a model for polyproline.

  Biophysical chemistry 20050101

• The AtProT family. Compatible solute transporters with similar substrate specificity but differential expression patterns.

  Plant physiology 20050101

• Double heterozygosity for a novel missense mutation of Ile304 to Asn in addition to the missense mutation His280 to Pro in the integrin beta3 gene as a cause of the absence of platelet alphaIIbbeta3 in Glanzmann's thrombasthenia.

  Journal of thrombosis and haemostasis : JTH 20050101

• Effect of 17beta-estradiol on tumor necrosis factor-alpha-induced cytotoxicity in the human peripheral T lymphocytes.

  The Journal of endocrinology 20050101

• Substrate specificity and functional characterisation of the H+/amino acid transporter rat PAT2 (Slc36a2).

  British journal of pharmacology 20050101

• Chiral separation of NBD-amino acids by ligand-exchange micro-channel electrophoresis.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20050101

• Proline residue-modified polycationic analogs of gramicidin S with high antibacterial activity against both Gram-positive and Gram-negative bacteria and low hemolytic activity.

  The journal of peptide research : official journal of the American Peptide Society 20050101

• Molecular evolution of amelogenin in mammals.

  Journal of molecular evolution 20050101

• [p53 gene codon 72 polymorphism and susceptibility to keloid in Chinese population].

  Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20050101

• A possible association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma2 gene with obesity in native Javanese in Indonesia.

  Diabetes/metabolism research and reviews 20050101

• Gel formation of peptides produced by extensive enzymatic hydrolysis of beta-lactoglobulin.

  Biomacromolecules 20050101

• Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-gamma coactivator-1 gene might be a risk factor for diabetic retinopathy in Slovene population (Caucasians) with type 2 diabetes and the Pro12Ala polymorphism of the PPARgamma gene is not.

  Diabetes/metabolism research and reviews 20050101

• Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population.

  BMC medical genetics 20050101

• [Dilept: a tripeptoid neurotensin analog combining neuroleptic activity with positive mnemotropic action].

  Eksperimental'naia i klinicheskaia farmakologiia 20050101

• In vivo antitumor effect of ascorbic acid, lysine, proline and green tea extract on human prostate cancer PC-3 xenografts in nude mice: evaluation of tumor growth and immunohistochemistry.

  In vivo (Athens, Greece) 20050101

• Prolidase, a potential enzyme target for melanoma: design of proline-containing dipeptide-like prodrugs.

  Molecular pharmaceutics 20050101

• Statistically significant dependence of the Xaa-Pro peptide bond conformation on secondary structure and amino acid sequence.

  BMC structural biology 20050101

• The therapeutic potential of inhibitors of dipeptidyl peptidase IV (DPP IV) and related proline-specific dipeptidyl aminopeptidases.

  Current medicinal chemistry 20050101

• Antitumor effect of a combination of lysine, proline, arginine, ascorbic acid, and green tea extract on pancreatic cancer cell line MIA PaCa-2.

  International journal of gastrointestinal cancer 20050101

• p53 Protein is activated by Pin1: and also by Cu-SOD prion-like enzyme.

  Medical hypotheses 20050101

• The role of potassium as an ionic signal in the regulation of cyanobacterium Nostoc muscorum response to salinity and osmotic stress.

  Journal of basic microbiology 20050101

• Synthesis and screening of a small library of proline-based biodendrimers for use as delivery agents.

  Biopolymers 20050101

• [Analgesic activity of dermorphin and its proline analogs].

  Eksperimental'naia i klinicheskaia farmakologiia 20050101

• Transforming growth factor-beta1 SNPs: genetic and phenotypic correlations in progressive kidney insufficiency.

  Nephron. Experimental nephrology 20050101

• Proline hydroxylation and gene expression.

  Annual review of biochemistry 20050101

• Regulation of gut function varies with life-history traits in chuckwallas (Sauromalus obesus: Iguanidae).

  Physiological and biochemical zoology : PBZ 20050101

• In vitro and in vivo antitumorigenic activity of a mixture of lysine, proline, ascorbic acid, and green tea extract on human breast cancer lines MDA-MB-231 and MCF-7.

  Medical oncology (Northwood, London, England) 20050101

• Arginine and proline alleles of the p53 gene are associated with different locations of gastric cancer.

  Hepato-gastroenterology 20050101

• Modulation of N-methyl-N-nitrosourea induced mammary tumors in Sprague-Dawley rats by combination of lysine, proline, arginine, ascorbic acid and green tea extract.

  Breast cancer research : BCR 20050101

• Functional polymorphism of the glutathione peroxidase 1 gene is associated with personality traits in healthy subjects.

  Neuropsychobiology 20050101

• Metabotropic glutamate receptor 2 modulates excitatory synaptic transmission in the rat globus pallidus.

  Neuropharmacology 20050101

• In vitro determination of the release kinetics of peptides and free amino acids during the digestion of food proteins.

  Journal of AOAC International 20050101

• Proton affinity of diastereoisomers of modified prolines using the kinetic method and density functional theory calculations: role of the cis/trans substituent on the endo/exo ring conformation.

  Rapid communications in mass spectrometry : RCM 20050101

• [Effects of glyprolines on development and healing of acetate ulcers in rats].

  Patologicheskaia fiziologiia i eksperimental'naia terapiia 20050101

• The Ramachandran plots of glycine and pre-proline.

  BMC structural biology 20050101

• In B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosis.

  BMC cancer 20050101

• Modification of porcine pancreatic lipase with Z-proline.

  Preparative biochemistry & biotechnology 20050101

• Methods for measuring hydroxyproline and estimating in vivo rates of collagen synthesis and degradation.

  Methods in molecular medicine 20050101

• The p53 codon 72 polymorphism and risk of high-grade cervical intraepithelial neoplasia.

  Cancer detection and prevention 20050101

• A rapid capillary electrophoresis with electrochemiluminescence method for the assay of human urinary proline and hydroxyproline.

  Luminescence : the journal of biological and chemical luminescence 20050101

• Antiandrogen-like actions of an antioxidant on survivin, Bcl-2 and PSA in human prostate cancer cells.

  Cancer detection and prevention 20050101

• Acute encephalopathy associated with influenza virus infection in a patient with hyperprolinaemia type II.

  Journal of inherited metabolic disease 20050101

• Synthesis of optically active trans 4-cyclohexyl-L-proline as an intermediate product in the preparation of fosinopril.

  Acta poloniae pharmaceutica 20050101

• Changes of glucose metabolism and skin-collagen neogenesis in vitamin B6 deficiency.

  BioFactors (Oxford, England) 20050101

• Effect of individual amino acids and glucose on activation and germination of Rhizopus oligosporus sporangiospores in tempe starter.

  Journal of applied microbiology 20050101

• An investigation of the divergence of major ampullate silk fibers from Nephila clavipes and Argiope aurantia.

  Biomacromolecules 20050101

• Characterization of a protein-based adhesive elastomer secreted by the Australian frog Notaden bennetti.

  Biomacromolecules 20050101

• Secondary structure assignment that accurately reflects physical and evolutionary characteristics.

  BMC bioinformatics 20050101

• Collagen structure in skin from fibromyalgia patients.

  International journal of tissue reactions 20050101

• Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: implications for nuclear toxicity in Huntington's disease pathogenesis.

  Neuromolecular medicine 20050101

• [The new tripeptoid neurotensin analog dilept selectively affects dopamine turnover in nucleus accumbens and hypothalamus].

  Eksperimental'naia i klinicheskaia farmakologiia 20050101

• Cryopreservation of Prunus avium L. embryogenic tissues.

  Cryo letters 20050101

• The influence of the Pro12Ala mutation of PPARgamma2 receptor gene on beta-cells restoration and insulin resistance in type 2 diabetes with hypertension.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101

• Palmitoylation of inducible nitric-oxide synthase at Cys-3 is required for proper intracellular traffic and nitric oxide synthesis.

  The Journal of biological chemistry 20041231

• Many amino acid substitutions in a hypoxia-inducible transcription factor (HIF)-1alpha-like peptide cause only minor changes in its hydroxylation by the HIF prolyl 4-hydroxylases: substitution of 3,4-dehydroproline or azetidine-2-carboxylic acid for the proline leads to a high rate of uncoupled 2-oxoglutarate decarboxylation.

  The Journal of biological chemistry 20041231

• On the mechanism for neomycin reversal of wortmannin inhibition of insulin stimulation of glucose uptake.

  The Journal of biological chemistry 20041231

• Identification of amino acid residues that direct differential ligand selectivity of mammalian and nonmammalian V1a type receptors for arginine vasopressin and vasotocin. Insights into molecular coevolution of V1a type receptors and their ligands.

  The Journal of biological chemistry 20041224

• Charged residues at the 2' position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability.

  The Journal of biological chemistry 20041224

• Functional consequences of alterations to Thr247, Pro248, Glu340, Asp813, Arg819, and Arg822 at the interfaces between domain P, M3, and L6-7 of sarcoplasmic reticulum Ca2+-ATPase. Roles in Ca2+ interaction and phosphoenzyme processing.

  The Journal of biological chemistry 20041224

• Granzyme M is a regulatory protease that inactivates proteinase inhibitor 9, an endogenous inhibitor of granzyme B.

  The Journal of biological chemistry 20041224

• Impact of azaproline on Peptide conformation.

  The Journal of organic chemistry 20041224

• Identification, expression analysis and polymorphism of a novel RLTPR gene encoding a RGD motif, tropomodulin domain and proline/leucine-rich regions.

  Gene 20041222

• Probing the active catalyst in product-accelerated proline-mediated reactions.

  Journal of the American Chemical Society 20041222

• The synthesis of SNAT2 transporters is required for the hypertonic stimulation of system A transport activity.

  Biochimica et biophysica acta 20041215

• Activity regulation of the betaine transporter BetP of Corynebacterium glutamicum in response to osmotic compensation.

  Biochimica et biophysica acta 20041215

• Membrane translocation mechanism of the antimicrobial peptide buforin 2.

  Biochemistry 20041214

• Analysis of the secondary structure of beta-amyloid (Abeta42) fibrils by systematic proline replacement.

  The Journal of biological chemistry 20041210

• Substituted 2-azabicyclo[2.1.1]hexanes as constrained proline analogues: implications for collagen stability.

  The Journal of organic chemistry 20041210

• Pseudoprolines as removable turn inducers: tools for the cyclization of small peptides.

  The Journal of organic chemistry 20041210

• Synthesis and alpha4beta2 nicotinic affinity of 2-pyrrolidinylmethoxyimines and prolinal oxime ethers.

  Bioorganic & medicinal chemistry letters 20041206

• p53-dependent down-regulation of telomerase is mediated by p21waf1.

  The Journal of biological chemistry 20041203

• Myristoylation, a protruding loop, and structural plasticity are essential features of a nonenveloped virus fusion peptide motif.

  The Journal of biological chemistry 20041203

• Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site 3: role of site-specific mutations.

  Chembiochem : a European journal of chemical biology 20041203

• DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: one involves direct binding to the cdc25C promoter.

  Molecular cell 20041203

• Zn2[(S)-O3PCH2NHC4H7CO2]2: a homochiral 3D zinc phosphonate with helical channels.

  Angewandte Chemie (International ed. in English) 20041203

• Hepatocyte nuclear factors 1alpha and 4alpha control expression of proline oxidase in adult liver.

  FEBS letters 20041203

• Cyclophilin A functions as an endogenous inhibitor for membrane-bound guanylate cyclase-A.

  Hypertension (Dallas, Tex. : 1979) 20041201

• Elucidation of the isomeric domains formed by sodium N-dodecanoyl-L-prolinate.

  Journal of colloid and interface science 20041201

• Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study.

  Arteriosclerosis, thrombosis, and vascular biology 20041201

• Response of antioxidants in sunflower (Helianthus annuus L.) grown on different amendments of tannery sludge: its metal accumulation potential.

  Chemosphere 20041201

• Characterization of the in vivo forms of lacrimal-specific proline-rich proteins in human tear fluid.

  Proteomics 20041201

• The role of [Delta]1-pyrroline-5-carboxylate dehydrogenase in proline degradation.

  The Plant cell 20041201

• SHIP2 is recruited to the cell membrane upon macrophage colony-stimulating factor (M-CSF) stimulation and regulates M-CSF-induced signaling.

  Journal of immunology (Baltimore, Md. : 1950) 20041201

• Azetidine-induced accumulation of class I small heat shock proteins in the soluble fraction provides thermotolerance in soybean seedlings.

  Plant & cell physiology 20041201

• Renal apolipoprotein A-I amyloidosis associated with a novel mutant Leu64Pro.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20041201

• Conformationally locked isostere of phosphoSer-cis-Pro inhibits Pin1 23-fold better than phosphoSer-trans-Pro isostere.

  Journal of the American Chemical Society 20041201

• Severe hypercalcemia in a 9-year-old Brazilian girl due to a novel inactivating mutation of the calcium-sensing receptor.

  The Journal of clinical endocrinology and metabolism 20041201

• An analysis of the genetic factors involved in testicular descent in a cohort of 14 male patients with anorchia.

  The Journal of clinical endocrinology and metabolism 20041201

• Chromosomal localization of three somatostatin genes in zebrafish. Evidence that the [Pro2]-somatostatin-14 isoform and cortistatin are encoded by orthologous genes.

  Journal of molecular endocrinology 20041201

• Nutrients released by gastric epithelial cells enhance Helicobacter pylori growth.

  Helicobacter 20041201

• A comprehensive expression analysis of the Arabidopsis proline-rich extensin-like receptor kinase gene family using bioinformatic and experimental approaches.

  Plant & cell physiology 20041201

• Influence of proline on rat brain activities of alanine aminotransferase, aspartate aminotransferase and acid phosphatase.

  Neurochemical research 20041201

• Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline.

  Journal of alternative and complementary medicine (New York, N.Y.) 20041201

• NMR solution structure of the archaebacterial chromosomal protein MC1 reveals a new protein fold.

  Biochemistry 20041130

• Involvement of the C-terminal proline-rich motif of G protein-coupled receptor kinases in recognition of activated rhodopsin.

  The Journal of biological chemistry 20041126

• Novel assembly properties of recombinant spider dragline silk proteins.

  Current biology : CB 20041123

• Degradation of the gluconeogenic enzymes fructose-1,6-bisphosphatase and malate dehydrogenase is mediated by distinct proteolytic pathways and signaling events.

  The Journal of biological chemistry 20041119

• Protein phosphatase 4 is a positive regulator of hematopoietic progenitor kinase 1.

  The Journal of biological chemistry 20041119

• Assay and subcellular localization of pyrroline-5-carboxylate dehydrogenase in rat liver.

  Biochimica et biophysica acta 20041118

• Effects of a redox-active agent on lymphocyte activation and early gene expression patterns.

  Free radical biology & medicine 20041115

• Structural basis for the binding of compatible solutes by ProX from the hyperthermophilic archaeon Archaeoglobus fulgidus.

  The Journal of biological chemistry 20041112

• The roles of amino acid residues at positions 43 and 45 in microsomal contents and enzymatic functions of rat CYP2D1 and CYP2D2.

  Biochemical and biophysical research communications 20041112

• Folding mechanism of the CH2 antibody domain.

  Journal of molecular biology 20041112

• Asymmetric synthesis of 3-substituted proline chimeras bearing polar side chains of proteinogenic amino acids.

  The Journal of organic chemistry 20041112

• Large structural modification with conserved conformation: analysis of delta(3)-fused aryl prolines in model beta-turns.

  Journal of the American Chemical Society 20041110

• Investigation of the role of the N-terminal proline, the distal heme ligand in the CO sensor CooA.

  Biochemistry 20041109

• L-proline catalyzed asymmetric transfer aldol reaction between diacetone alcohol and aldehydes.

  Chemical communications (Cambridge, England) 20041107

• Protein kinase CK2 is an inhibitor of the neuronal Cdk5 kinase.

  The Journal of biological chemistry 20041105

• Computational evidence for the enamine mechanism of intramolecular aldol reactions catalyzed by proline.

  Angewandte Chemie (International ed. in English) 20041105

• Identification and characterisation of a novel KCNQ1 mutation in a family with Romano-Ward syndrome.

  Biochimica et biophysica acta 20041105

• A cyclopent-2-enecarbonyl group mimics proline at the P2 position of prolyl oligopeptidase inhibitors.

  Journal of medicinal chemistry 20041104

• Long-range electron transfer across Peptide bridges: the transition from electron superexchange to hopping.

  Journal of the American Chemical Society 20041103

• Origins of selectivities in proline-catalyzed alpha-aminoxylations.

  Journal of the American Chemical Society 20041103

• Folding and domain-domain interactions of the chaperone PapD measured by 19F NMR.

  Biochemistry 20041102

• A common antitussive drug, clobutinol, precipitates the long QT syndrome 2.

  Molecular pharmacology 20041101

• Changes in water status and proline and abscisic acid concentrations in developing somatic embryos of pedunculate oak (Quercus robur) during maturation and germination.

  Tree physiology 20041101

• Actin mutations are one cause of congenital fibre type disproportion.

  Annals of neurology 20041101

• Vpx proteins of SIVmac239 and HIV-2ROD interact with the cytoskeletal protein alpha-actinin 1.

  The Journal of general virology 20041101

• Structural and functional studies of mutations affecting the UBA domain of SQSTM1 (p62) which cause Paget's disease of bone.

  Biochemical Society transactions 20041101

• Computational peptide dissection of Melan-a/MART-1 oncoprotein antigenicity.

  Peptides 20041101

• Inhibition of mitogen-mediated proliferation of rat vascular smooth muscle cells by labedipinedilol-A through PKC and ERK 1/2 pathway.

  Journal of cardiovascular pharmacology 20041101

• Gender dependent association of thrombospondin-4 A387P polymorphism with myocardial infarction.

  Arteriosclerosis, thrombosis, and vascular biology 20041101

• Lattice corneal dystrophy associated with the Ala546Asp and Pro551Gln missense changes in the TGFBI gene.

  American journal of ophthalmology 20041101

• Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin.

  European journal of biochemistry 20041101

• [Determination of stachydrine and leonurine in Herba Leonuri by ion- pair reversed-phase high-performance liquid chromatography].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20041101

• Importance of N source on heat stress tolerance due to the accumulation of proline and quaternary ammonium compounds in tomato plants.

  Plant biology (Stuttgart, Germany) 20041101

• Effect of drought and rewatering on the metabolism of Lupinus albus organs.

  Journal of plant physiology 20041101

• Photosynthetic response of transgenic soybean plants, containing an Arabidopsis P5CR gene, during heat and drought stress.

  Journal of plant physiology 20041101

• [Association of p53 gene polymorphism with susceptibility to ovarian cancer].

  Zhonghua fu chan ke za zhi 20041101

• Family of two patients with congenital lipoid adrenal hyperplasia due to StAR mutation.

  Endocrine research 20041101

• A male twin infant with skull deformity and elevated neonatal 17-hydroxyprogesterone: a prismatic case of P450 oxidoreductase deficiency.

  Endocrine research 20041101

• Dynamic changes in intranuclear and subcellular localizations of mouse Prrp/DAZAP1 during spermatogenesis: the necessity of the C-terminal proline-rich region for nuclear import and localization.

  Archives of histology and cytology 20041101

• Post-translational modifications of arabinogalactan-peptides of Arabidopsis thaliana. Endoplasmic reticulum and glycosylphosphatidylinositol-anchor signal cleavage sites and hydroxylation of proline.

  The Journal of biological chemistry 20041029

• Charge translocation during cosubstrate binding in the Na+/proline transporter of E.coli.

  Journal of molecular biology 20041029

• AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation.

  The Journal of biological chemistry 20041022

• A novel method of analyzing proline synonymous codons in E. coli.

  FEBS letters 20041022

• Identification and specificity studies of small-molecule ligands for SH3 protein domains.

  Journal of medicinal chemistry 20041021

• Evaluation of lactam-bridged neurotensin analogues adjusting psi(Pro10) close to the experimentally derived bioactive conformation of NT(8-13).

  Journal of medicinal chemistry 20041021

• Chiral recognition of dipeptides in a biomembrane model.

  Journal of the American Chemical Society 20041020

• Regulation of PutA-membrane associations by flavin adenine dinucleotide reduction.

  Biochemistry 20041019

• Potent and selective proline derived dipeptidyl peptidase IV inhibitors.

  Bioorganic & medicinal chemistry letters 20041018

• Raman optical activity demonstrates poly(L-proline) II helix in the N-terminal region of the ovine prion protein: implications for function and misfunction.

  Journal of molecular biology 20041015

• Asymptomatic hereditary Alexander's disease caused by a novel mutation in GFAP.

  Journal of the neurological sciences 20041015

• Diastereoselective [2+2]-cycloaddition reactions of unsymmetrical cyclic ketenes with imines: synthesis of modified prolines and theoretical study of the reaction mechanism.

  The Journal of organic chemistry 20041015

• Conformational studies of peptides containing cis-3-hydroxy-D-proline.

  The Journal of organic chemistry 20041015

• Structure and function of the NPC2 protein.

  Biochimica et biophysica acta 20041011

• The alphaM1 segment of the nicotinic acetylcholine receptor exhibits conformational flexibility in a membrane environment.

  Biochimica et biophysica acta 20041011

• Interaction of the BMPR-IA tumor suppressor with a developmentally relevant splicing factor.

  Biochemical and biophysical research communications 20041008

• A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease.

  Journal of the American College of Cardiology 20041006

• Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors.

  Biochemistry 20041005

• NF-kappaB activation is required for the development of cardiac hypertrophy in vivo.

  American journal of physiology. Heart and circulatory physiology 20041001

• p53 polymorphism in human papillomavirus-associated Kazakh's esophageal cancer in Xinjiang, China.

  World journal of gastroenterology 20041001

• Release of short and proline-rich antihypertensive peptides from casein hydrolysate with an Aspergillus oryzae protease.

  Journal of dairy science 20041001

• Cis-trans isomerization and puckering of proline residue.

  Biophysical chemistry 20041001

• The modified wobble nucleoside uridine-5-oxyacetic acid in tRNAPro(cmo5UGG) promotes reading of all four proline codons in vivo.

  RNA (New York, N.Y.) 20041001

• Characterization of beta-keratins and associated proteins in adult and regenerating epidermis of lizards.

  Tissue & cell 20041001

• Structure of Escherichia coli aminopeptidase P in complex with the inhibitor apstatin.

  Acta crystallographica. Section D, Biological crystallography 20041001

• Bacteroid proline catabolism affects N(2) fixation rate of drought-stressed soybeans.

  Plant physiology 20041001

• A novel IMPDH1 mutation (Arg231Pro) in a family with a severe form of autosomal dominant retinitis pigmentosa.

  Ophthalmology 20041001

• Ena/VASP family: new partners, bigger enigma.

  Developmental cell 20041001

• RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion.

  Developmental cell 20041001

• Proline-coated column for the capillary electrochromatographic separation of amino acids by in-column derivatization.

  Electrophoresis 20041001

• Association of male infertility with Pro185Ala polymorphism in the aryl hydrocarbon receptor repressor gene: implication for the susceptibility to dioxins.

  Fertility and sterility 20041001

• Phenotypic features and genetic findings in 2 chinese families with Miyoshi distal myopathy.

  Archives of neurology 20041001

• Abnormal metabotropic glutamate receptor expression and signaling in the cerebral cortex in diffuse Lewy body disease is associated with irregular alpha-synuclein/phospholipase C (PLCbeta1) interactions.

  Brain pathology (Zurich, Switzerland) 20041001

• Effects of histidine-proline-rich glycoprotein on plasminogen activation in solution and on surfaces.

  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20041001

• A new set of monoclonal antibodies directed to proline-rich and central regions of p53.

  Hybridoma and hybridomics 20041001

• [Is obesity associated with a polymorphism Pro12Ala and Pro115Gln in the PPARgamma gene?].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20041001

• Direct organocatalytic asymmetric aldol reactions of alpha-amino aldehydes: expedient syntheses of highly enantiomerically enriched anti-beta-hydroxy-alpha-amino acids.

  Organic letters 20040930

• In situ catalyst improvement in the proline-mediated alpha-amination of aldehydes.

  Journal of the American Chemical Society 20040929

• Expression of transglutaminase substrate activity on Candida albicans germ tubes through a coiled, disulfide-bonded N-terminal domain of Hwp1 requires C-terminal glycosylphosphatidylinositol modification.

  The Journal of biological chemistry 20040924

• Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress.

  The Journal of biological chemistry 20040924

• A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.

  Molecular cell 20040924

• Molecular structure of proline.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20040920

• Two-step synthesis of carbohydrates by selective aldol reactions.

  Science (New York, N.Y.) 20040917

• Chemistry. A dash of proline makes things sweet.

  Science (New York, N.Y.) 20040917

• Total synthesis of (+)-cocaine via desymmetrization of a meso-dialdehyde.

  Organic letters 20040916

• Asymmetric synthesis of alpha-amino 1,3-dithioketals from sulfinimines (N-sulfinyl imines). Synthesis of (2S,3R)-(-)-3-hydroxy-3-methylproline.

  Organic letters 20040916

• Effects of endothelin-1 on hepatic stellate cell proliferation, collagen synthesis and secretion, intracellular free calcium concentration.

  World journal of gastroenterology 20040915

• Oxidation of 3,4-dehydro-D-proline and other D-amino acid analogues by D-alanine dehydrogenase from Escherichia coli.

  FEMS microbiology letters 20040915

• Structural basis for the role in protein folding of conserved proline-rich regions in cytochromes P450.

  Toxicology and applied pharmacology 20040915

• A case of complicated spastic paraplegia 2 due to a point mutation in the proteolipid protein 1 gene.

  Journal of the neurological sciences 20040915

• The effect of penetration enhancers on drug delivery through skin: a QSAR study.

  Journal of controlled release : official journal of the Controlled Release Society 20040914

• Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2).

  Biochemistry 20040914

• Expression of a nonpolymerizable actin mutant in Sf9 cells.

  Biochemistry 20040914

• Asb6, an adipocyte-specific ankyrin and SOCS box protein, interacts with APS to enable recruitment of elongins B and C to the insulin receptor signaling complex.

  The Journal of biological chemistry 20040910

• A functional aquaporin co-localizes with the vacuolar proton pyrophosphatase to acidocalcisomes and the contractile vacuole complex of Trypanosoma cruzi.

  The Journal of biological chemistry 20040910

• New mutation (T1232P) of the ATP-7B gene associated with neurologic and neuropsychiatric dominance onset of Wilson's disease in three unrelated Colombian kindred.

  Neuroscience letters 20040909

• Detailed investigation of the production of the bread flavor component 6-acetyl-1,2,3,4-tetrahydropyridine in proline/1,3-dihydroxyacetone model systems.

  Journal of agricultural and food chemistry 20040908

• A case study of 2,2-dimethylthiazolidine as locked cis proline amide bond: synthesis, NMR and molecular modeling studies of a delta-conotoxin EVIA peptide analog.

  Organic & biomolecular chemistry 20040907

• First catalytic asymmetric synthesis of beta-amino-beta-polyfluoroalkyl ketones via proline-catalysed direct asymmetric carbon-carbon bond formation reaction of polyfluoroalkylated aldimines.

  Chemical communications (Cambridge, England) 20040907

• Evidence for differences in the metabolism of saxitoxin and C1+2 toxins in the freshwater cyanobacterium Cylindrospermopsis raciborskii T3.

  Biochimica et biophysica acta 20040906

• The homeoprotein Alx3 contains discrete functional domains and exhibits cell-specific and selective monomeric binding and transactivation.

  The Journal of biological chemistry 20040903

• NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in Saccharomyces cerevisiae.

  The Journal of biological chemistry 20040903

• A miniprotein scaffold used to assemble the polyproline II binding epitope recognized by SH3 domains.

  Journal of molecular biology 20040903

• Direct proline-catalyzed asymmetric alpha-aminoxylation of aldehydes and ketones.

  The Journal of organic chemistry 20040903

• Collagen turnover is diminished by different clones of skin fibroblasts from early- but not late-stage systemic sclerosis.

  Rheumatology international 20040901

• The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo ischaemia-induced cell death.

  Cell death and differentiation 20040901

• Arginine synthesis is regulated by dietary arginine intake in the enterally fed neonatal piglet.

  American journal of physiology. Endocrinology and metabolism 20040901

• Obligatory involvement of CD26/dipeptidyl peptidase IV in the activation of the antiretroviral tripeptide glycylprolylglycinamide (GPG-NH(2)).

  The international journal of biochemistry & cell biology 20040901

• Hyporesponsiveness in alloreactive T-cells by NF-kappaB inhibitor-treated dendritic cells: resistance to calcineurin inhibition.

  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040901

• YC-1-induced cyclooxygenase-2 expression is mediated by cGMP-dependent activations of Ras, phosphoinositide-3-OH-kinase, Akt, and nuclear factor-kappaB in human pulmonary epithelial cells.

  Molecular pharmacology 20040901

• High incidence of type 2 diabetes in peroxisome proliferator-activated receptor gamma2 Pro12Ala carriers exposed to a high chronic intake of trans fatty acids and saturated fatty acids.

  Diabetes care 20040901

• Leucine7 to proline7 polymorphism in prepro-NPY gene and femoral neck bone mineral density in postmenopausal women.

  Bone 20040901

• The CAP-Gly domain of CYLD associates with the proline-rich sequence in NEMO/IKKgamma.

  Structure (London, England : 1993) 20040901

• Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri.

  Microbiology (Reading, England) 20040901

• LWR1 and LWR2 are required for osmoregulation and osmotic adjustment in Arabidopsis.

  Plant physiology 20040901

• Irregular dimerization of guanylate cyclase-activating protein 1 mutants causes loss of target activation.

  European journal of biochemistry 20040901

• Escherichia coli cyclophilin B binds a highly distorted form of trans-prolyl peptide isomer.

  European journal of biochemistry 20040901

• Antimicrobial resistance of Neisseria gonorrhoeae in Japan, 1993-2002: continuous increasing of ciprofloxacin-resistant isolates.

  International journal of antimicrobial agents 20040901

• Electronic structure of the nickel(II) complex of the Schiff base of (S)-N-(2-benzoylphenyl)-1-benzylprolinamide and glycine.

  Acta crystallographica. Section A, Foundations of crystallography 20040901

• Is osmotic adjustment required for water stress resistance in the Mediterranean shrub Atriplex halimus L?

  Journal of plant physiology 20040901

• Selective loss of codon 72 proline p53 and frequent mutational inactivation of the retained arginine allele in colorectal cancer.

  Neoplasia (New York, N.Y.) 20040901

• Novel prolyl tri/tetra-peptidyl aminopeptidase from Streptomyces mobaraensis: substrate specificity and enzyme gene cloning.

  Journal of biochemistry 20040901

• Deletion and purification studies to elucidate the structure of the Actinobacillus actinomycetemcomitans cytolethal distending toxin.

  Journal of biochemistry 20040901

• Probing the reaction pathways of DL-proline on TiO2 (001) single crystal surfaces.

  Langmuir : the ACS journal of surfaces and colloids 20040831

• The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK.

  The Journal of biological chemistry 20040827

• Structural mechanism governing cis and trans isomeric states and an intramolecular switch for cis/trans isomerization of a non-proline peptide bond observed in crystal structures of scorpion toxins.

  Journal of molecular biology 20040827

• LcoP, an osmoregulated betaine/ectoine uptake system from Corynebacterium glutamicum.

  FEBS letters 20040827

• Study of the role of the carbohydrate and protein moieties of soy soluble polysaccharides in their emulsifying properties.

  Journal of agricultural and food chemistry 20040825

• A likely biogenetic gateway linking 2-aminoimidazolinone metabolites of sponges to proline: spontaneous oxidative conversion of the pyrrole-proline-guanidine pseudo-peptide to dispacamide A.

  Journal of the American Chemical Society 20040825

• Synthesis and solid state conformation of phenylalanine mimetics constrained in a proline-like conformation.

  Organic & biomolecular chemistry 20040821

• Novel asymmetric approach to proline-derived spiro-beta-lactams.

  The Journal of organic chemistry 20040820

• Characterization of the conformational behavior of peptide Contryphan Vn: a theoretical study.

  Biopolymers 20040815

• NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding.

  The Journal of biological chemistry 20040813

• The proline-rich homeodomain protein recruits members of the Groucho/Transducin-like enhancer of split protein family to co-repress transcription in hematopoietic cells.

  The Journal of biological chemistry 20040813

• Association of immunophilins with mammalian TRPC channels.

  The Journal of biological chemistry 20040813

• Caspase-mediated specific cleavage of human histone deacetylase 4.

  The Journal of biological chemistry 20040813

• Alanine-scanning mutagenesis in the signature disulfide loop of the glycine receptor alpha 1 subunit: critical residues for activation and modulation.

  Biochemistry 20040810

• The direct catalytic asymmetric alpha-aminooxylation reaction: development of stereoselective routes to 1,2-diols and 1,2-amino alcohols and density functional calculations.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20040806

• Genetic polymorphisms in human proton-dependent dipeptide transporter PEPT1: implications for the functional role of Pro586.

  The Journal of pharmacology and experimental therapeutics 20040801

• Short-term peaks in glucose promote renal fibrogenesis independently of total glucose exposure.

  American journal of physiology. Renal physiology 20040801

• Arbuscular mycorrhizal influence on leaf water potential, solute accumulation, and oxidative stress in soybean plants subjected to drought stress.

  Journal of experimental botany 20040801

• L-proline is essential for the intracellular differentiation of Trypanosoma cruzi.

  Cellular microbiology 20040801

• Lithium suppressed Tyr-402 phosphorylation of proline-rich tyrosine kinase (Pyk2) and interactions of Pyk2 and PSD-95 with NR2A in rat hippocampus following cerebral ischemia.

  Neuroscience research 20040801

• Altered GABAB receptor immunoreactivity in the gerbil hippocampus induced by baclofen and phaclofen, not seizure activity.

  Neuroscience research 20040801

• Increased risk of bladder cancer associated with a glutathione peroxidase 1 codon 198 variant.

  The Journal of urology 20040801

• Expressing and purifying an anti-atherosclerosis polypeptide vaccine in Escherichia coli.

  Protein expression and purification 20040801

• A novel NOG mutation Pro37Arg in a family with tarsal and carpal synostoses.

  American journal of medical genetics. Part A 20040801

• Antigen presentation to celiac lesion-derived T cells of a 33-mer gliadin peptide naturally formed by gastrointestinal digestion.

  Journal of immunology (Baltimore, Md. : 1950) 20040801

• Cyclic strain stimulates L-proline transport in vascular smooth muscle cells.

  American journal of hypertension 20040801

• Effect of mutational inactivation of tyrosine kinase activity on BCR/ABL-induced abnormalities in cell growth and adhesion in human hematopoietic progenitors.

  Cancer research 20040801

• Substrate specificity and transport mode of the proton-dependent amino acid transporter mPAT2.

  European journal of biochemistry 20040801

• EspFU is a translocated EHEC effector that interacts with Tir and N-WASP and promotes Nck-independent actin assembly.

  Developmental cell 20040801

• Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk.

  Immunity 20040801

• The effect of sugar, amino acid, metal ion, and NaCl on model Maillard reaction under pH control.

  Amino acids 20040801

• Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs.

  Current opinion in structural biology 20040801

• Response to lysine intake in composition of body weight gain and efficiency of lysine utilization of growing male chickens from two genotypes.

  Poultry science 20040801

• Design, synthesis and antibacterial activity studies of model peptidess of proline/arginine-rich region in bactenecin7.

  Protein and peptide letters 20040801

• L-proline microinjected into the rat ventrolateral medulla induces a depressor response distinct from L-glutamate.

  The Japanese journal of physiology 20040801

• Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region.

  The Journal of biological chemistry 20040730

• Proline substitutions are not easily accommodated in a membrane protein.

  Journal of molecular biology 20040730

• Common mechanism of ligand recognition by group II/III WW domains: redefining their functional classification.

  The Journal of biological chemistry 20040723

• Synthesis of 3 10-helix-inducing constrained analogues of L-proline.

  The Journal of organic chemistry 20040723

• Virtually complete control of simple and face diastereoselectivity in the Michael addition reactions between achiral equivalents of a nucleophilic glycine and (S)- or (R)-3-(E-enoyl)-4-phenyl-1,3-oxazolidin-2-ones: practical method for preparation of beta-substituted pyroglutamic acids and prolines.

  The Journal of organic chemistry 20040723

• Catalytic route to the synthesis of optically active beta,beta-difluoroglutamic acid and beta,beta-difluoroproline derivatives.

  The Journal of organic chemistry 20040723

• BetP of Corynebacterium glutamicum, a transporter with three different functions: betaine transport, osmosensing, and osmoregulation.

  Biochimica et biophysica acta 20040723

• Asymmetric synthesis of quaternary alpha- and beta-amino acids and beta-lactams via proline-catalyzed mannich reactions with branched aldehyde donors.

  Organic letters 20040722

• Direct asymmetric organocatalytic Michael reactions of alpha,alpha-disubstituted aldehydes with beta-nitrostyrenes for the synthesis of quaternary carbon-containing products.

  Organic letters 20040722

• Hepatitis C virus glycoprotein E2 contains a membrane-proximal heptad repeat sequence that is essential for E1E2 glycoprotein heterodimerization and viral entry.

  The Journal of biological chemistry 20040716

• Histidine-rich glycoprotein binds to cell-surface heparan sulfate via its N-terminal domain following Zn2+ chelation.

  The Journal of biological chemistry 20040716

• Proline homozygosity in codon 72 of p53 is a factor of susceptibility for thyroid cancer.

  Cancer letters 20040716

• Association of p53 genetic polymorphism (Arg72Pro) with estrogen receptor positive breast cancer risk in Japanese women.

  Cancer letters 20040716

• Design of temperature sensitive imprinted polymer hydrogels based on multiple-point hydrogen bonding.

  Macromolecular bioscience 20040714

• Structure of the plasminogen kringle 4 binding calcium-free form of the C-type lectin-like domain of tetranectin.

  Biochemistry 20040713

• The LEF-1 high-mobility group domain undergoes a disorder-to-order transition upon formation of a complex with cognate DNA.

  Biochemistry 20040713

• Synthesis of fused heteroarylprolines and pyrrolopyrroles.

  The Journal of organic chemistry 20040709

• Zinc-proline catalyzed pathway for the formation of sugars.

  Chemical communications (Cambridge, England) 20040707

• Conservation and expression of an alternative 3' exon of Runx2 encoding a novel proline-rich C-terminal domain.

  Gene 20040707

• The hydrogen bonds between Arg423 and Glu472 and other key residues, Asp443, Ser477, and Pro489, are responsible for the formation and a different positioning of TNP-ATP and ATP within the nucleotide-binding site of Na(+)/K(+)-ATPase.

  Biochemistry 20040706

• Cotranslational incorporation of a structurally diverse series of proline analogues in an Escherichia coli expression system.

  Chembiochem : a European journal of chemical biology 20040705

• Recognition sequences for the GYF domain reveal a possible spliceosomal function of CD2BP2.

  The Journal of biological chemistry 20040702

• Roles of a conserved proline in the internal fusion peptide of Ebola glycoprotein.

  FEBS letters 20040702

• Relationship between copper- and zinc-induced oxidative stress and proline accumulation in Scenedesmus sp.

  Planta 20040701

• Restoration of wild-type conformation to full-length and truncated p53 proteins: specific effects of ATP and ADP.

  Cancer biology & therapy 20040701

• HNPCC mutation MLH1 P648S makes the functional protein unstable, and homozygosity predisposes to mild neurofibromatosis type 1.

  Genes, chromosomes & cancer 20040701

• Homocysteine increases the production of asymmetric dimethylarginine in cultured neurons.

  Journal of neuroscience research 20040701

• Redox state regulates HIF-1alpha and its DNA binding and phosphorylation in salmonid cells.

  Journal of cell science 20040701

• Lack of major involvement of human uroplakin genes in vesicoureteral reflux: implications for disease heterogeneity.

  Kidney international 20040701

• 1H-, 13C- and 15N-NMR assignment of the conserved hypothetical protein TM0487 from Thermotoga maritima.

  Journal of biomolecular NMR 20040701

• The SH3 domain of Tec kinase is essential for its targeting to activated CD28 costimulatory molecule.

  European journal of immunology 20040701

• Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma.

  Human mutation 20040701

• Proline betaine accumulation and metabolism in alfalfa plants under sodium chloride stress. Exploring its compartmentalization in nodules.

  Plant physiology 20040701

• A novel point mutation of the RET protooncogene involving the second intracellular tyrosine kinase domain in a family with medullary thyroid carcinoma.

  The Journal of clinical endocrinology and metabolism 20040701

• Comparative genomics in salt tolerance between Arabidopsis and aRabidopsis-related halophyte salt cress using Arabidopsis microarray.

  Plant physiology 20040701

• Allergen activates peripheral blood eosinophil nuclear factor-kappaB to generate granulocyte macrophage-colony stimulating factor, tumour necrosis factor-alpha and interleukin-8.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040701

• Computational identification and characterization of novel genes from legumes.

  Plant physiology 20040701

• New information on the mechanism of forcible ascospore discharge from Ascobolus immersus.

  Fungal genetics and biology : FG & B 20040701

• Arginine revisited: minireview article.

  Amino acids 20040701

• Effect of peptide Pro-Gly-Pro on stress-induced behavioral changes in rats.

  Bulletin of experimental biology and medicine 20040701

• Inhibition of nuclear factor-kappa B prevents staphylococcal enterotoxin A-induced fever.

  Molecular and cellular biochemistry 20040701

• A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040630

• Dynamic influences on a high-affinity, high-specificity interaction involving the C-terminal SH3 domain of p67phox.

  Biochemistry 20040629

• WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins.

  Oncogene 20040624

• Small peptides catalyze highly enantioselective direct aldol reactions of aldehydes with hydroxyacetone: unprecedented regiocontrol in aqueous media.

  Organic letters 20040624

• Amplification of enantiomeric excess in a proline-mediated reaction.

  Angewandte Chemie (International ed. in English) 20040621

• Heterogeneous nuclear ribonuclear protein U associates with YAP and regulates its co-activation of Bax transcription.

  The Journal of biological chemistry 20040618

• Design of peptoid analogue dimers and measure of their affinity for Grb2 SH3 domains.

  Biochemistry 20040615

• Characteristics of selenazolidine prodrugs of selenocysteine: toxicity, selenium levels, and glutathione peroxidase induction in A/J mice.

  Life sciences 20040611

• Espins are multifunctional actin cytoskeletal regulatory proteins in the microvilli of chemosensory and mechanosensory cells.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040609

• Biochemical demonstration of the involvement of fatty acyl-CoA synthetase in fatty acid translocation across the plasma membrane.

  The Journal of biological chemistry 20040604

• Catalysis of proline-directed protein phosphorylation by peptidyl-prolyl cis/trans isomerases.

  Journal of molecular biology 20040604

• Analysis of polymorphisms at the tumor suppressor gene p53 (TP53) in contributing to the risk for schizophrenia and its associated neurocognitive deficits.

  Neuroscience letters 20040603

• Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125.

  The EMBO journal 20040602

• Metabolism of MDCK cells during cell growth and influenza virus production in large-scale microcarrier culture.

  Vaccine 20040602

• Leu-574 of human HIF-1alpha is a molecular determinant of prolyl hydroxylation.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040601

• Replacement of proline with valine does not remove an apparent proline isomerization-dependent folding event in CRABP I.

  Protein science : a publication of the Protein Society 20040601

• Salivary receptors for the proline-rich protein-binding and lectin-like adhesins of oral actinomyces and streptococci.

  Journal of dental research 20040601

• Agrobacterium proteins VirD2 and VirE2 mediate precise integration of synthetic T-DNA complexes in mammalian cells.

  EMBO reports 20040601

• Changes in insulin sensitivity in response to troglitazone do not differ between subjects with and without the common, functional Pro12Ala peroxisome proliferator-activated receptor-gamma2 gene variant: results from the Troglitazone in Prevention of Diabetes (TRIPOD) study.

  Diabetes care 20040601

• Molecular recognition properties of FN3 monobodies that bind the Src SH3 domain.

  Chemistry & biology 20040601

• Hyperhydricity of Prunus avium shoots cultured on gelrite: a controlled stress response.

  Plant physiology and biochemistry : PPB 20040601

• Effect of NaCl and mannitol iso-osmotic stresses on proline and free polyamine levels in embryogenic Fraxinus angustifolia callus.

  Journal of plant physiology 20040601

• Novel CLCN1 mutations in Taiwanese patients with myotonia congenita.

  Journal of neurology 20040601

• Engineering a thermostable human prolyl endopeptidase for antibody-directed enzyme prodrug therapy.

  Biochemistry 20040525

• The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling.

  The Journal of biological chemistry 20040521

• Conformationally tailored N-[(2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl)carbonyl]proline templates as molecular tools for the design of peptidomimetics. Design and synthesis of fibrinogen receptor antagonists.

  Organic & biomolecular chemistry 20040521

• Ursolic acid, an antagonist for transforming growth factor (TGF)-beta1.

  FEBS letters 20040521

• A new class of foldamers based on cis-gamma-amino-L-proline.

  Journal of the American Chemical Society 20040519

• Role of the conserved arginine pair in proton and electron transfer in cytochrome C oxidase.

  Biochemistry 20040518

• Comparison between catalase-peroxidase and cytochrome c peroxidase. The role of the hydrogen-bond networks for protein stability and catalysis.

  Biochemistry 20040518

• Short sequences of non-proline residues can adopt the polyproline II helical conformation.

  Biochemistry 20040518

• Discrimination of single amino acid mutations of the p53 protein by means of deterministic singularities of recurrence quantification analysis.

  Proteins 20040515

• Disruption of the toxic conformation of the expanded polyglutamine stretch leads to suppression of aggregate formation and cytotoxicity.

  Biochemical and biophysical research communications 20040514

• Severity of osteogenesis imperfecta and structure of a collagen-like peptide modeling a lethal mutation site.

  Biochemistry 20040511

• Synthesis of novel potent dipeptidyl peptidase IV inhibitors with enhanced chemical stability: interplay between the N-terminal amino acid alkyl side chain and the cyclopropyl group of alpha-aminoacyl-l-cis-4,5-methanoprolinenitrile-based inhibitors.

  Journal of medicinal chemistry 20040506

• Brain-specific RGS9-2 is localized to the nucleus via its unique proline-rich domain.

  Biochimica et biophysica acta 20040503

• Proteasome inhibitors up-regulate haem oxygenase-1 gene expression: requirement of p38 MAPK (mitogen-activated protein kinase) activation but not of NF-kappaB (nuclear factor kappaB) inhibition.

  The Biochemical journal 20040501

• Muenke syndrome.

  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20040501

• The signal transduction pathway that mediates the effect of interleukin-1 beta on the Na+-K+-ATPase in LLC-PK1 cells.

  Pflugers Archiv : European journal of physiology 20040501

• Inhibition of polyglutamine aggregate cytotoxicity by a structure-based elongation inhibitor.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040501

• Mutations of the 2' proline in the M2 domain of the human GABAC rho1 subunit alter agonist responses.

  Neuropharmacology 20040501

• Prolyl oligopeptidase is involved in release of the antifibrotic peptide Ac-SDKP.

  Hypertension (Dallas, Tex. : 1979) 20040501

• P53 codon 72 polymorphism and risk of gastric cancer in a Chinese population.

  Oncology reports 20040501

• A mutant impaired in SNARE complex dissociation identifies the plasma membrane as first target of synaptobrevin 2.

  Traffic (Copenhagen, Denmark) 20040501

• A proline-rich motif in the C terminus of Akt contributes to its localization in the immunological synapse.

  Journal of immunology (Baltimore, Md. : 1950) 20040501

• A microtitre format assay for proline in human serum or plasma.

  Clinica chimica acta; international journal of clinical chemistry 20040501

• Increase of cyclooxygenase-2 expression by interleukin 15 in rheumatoid synoviocytes.

  The Journal of rheumatology 20040501

• Functional analysis of two recurrent amino acid substitutions in the CYP21 gene from Italian patients with congenital adrenal hyperplasia.

  The Journal of clinical endocrinology and metabolism 20040501

• Liver biopsy discloses a new apolipoprotein A-I hereditary amyloidosis in several unrelated Italian families.

  Gastroenterology 20040501

• Expression of AT(1a) mRNA in rat hepatic stellate cells and its effects on cell growth collagen production.

  Chinese medical journal 20040501

• Hb Cardarelli [beta86(F2)Ala-->Pro]: a new unstable and hyperaffine variant in association with beta(+)-thalassemia.

  Hemoglobin 20040501

• A short alpha-helical antimicrobial peptide with antibacterial selectivity.

  Biotechnology letters 20040501

• Copper-induced oxidative stress in the chlorophycean microalga Chlorella vulgaris: response of the antioxidant system.

  Journal of plant physiology 20040501

• [Association of Pro12Ala mutation in peroxisome proliferator-activated receptor gamma 2 with obesity and diabetes in Chinese population].

  Wei sheng yan jiu = Journal of hygiene research 20040501

• [Is obesity associated with a polymorphism Pro12Ala and Pro115Gln in PPARgamma gene?].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20040501

• Pro7.33(303) of the human GnRH receptor regulates selective binding of mammalian GnRH.

  Molecular and cellular endocrinology 20040430

• Effects of Parkinson's disease-linked mutations on the structure of lipid-associated alpha-synuclein.

  Biochemistry 20040427

• The Pro-451 to Leu polymorphism within the C-terminal tail of P2X7 receptor impairs cell death but not phospholipase D activation in murine thymocytes.

  The Journal of biological chemistry 20040423

• Sorting competition with membrane-permeable peptides in intact epithelial cells revealed discrimination of transmembrane proteins not only at the trans-Golgi network but also at pre-Golgi stages.

  The Journal of biological chemistry 20040423

• Structural properties of cyclic peptides containing cis- or trans-2-aminocyclohexane carboxylic acid.

  Organic & biomolecular chemistry 20040421

• Sonochemical asymmetric hydrogenation of isophorone on proline modified Pd/Al2O3 catalysts.

  Chemical communications (Cambridge, England) 20040421

• Inhibitors of hepatitis C virus NS3.4A protease. Part 3: P2 proline variants.

  Bioorganic & medicinal chemistry letters 20040419

• Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040415

• Characterization of collagen-like heterotrimers: implications for triple-helix stability.

  Biopolymers 20040415

• Dirhodium(II) tetra(N-(dodecylbenzenesulfonyl)prolinate) catalyzed enantioselective cyclopropenation of alkynes.

  Organic letters 20040415

• The roles of active-site residues in the catalytic mechanism of trans-3-chloroacrylic acid dehalogenase: a kinetic, NMR, and mutational analysis.

  Biochemistry 20040413

• Roles of the proline-rich domain in SLP-76 subcellular localization and T cell function.

  The Journal of biological chemistry 20040409

• Phospholipase D is a negative regulator of proline biosynthesis in Arabidopsis thaliana.

  The Journal of biological chemistry 20040409

• Synthesis of aryl azides and vinyl azides via proline-promoted CuI-catalyzed coupling reactions.

  Chemical communications (Cambridge, England) 20040407

• Molecular dynamics simulations of glycosyltransferase LgtC.

  Carbohydrate research 20040402

• Conformational preferences and self-template macrocyclization of squaramide-based foldable modules.

  The Journal of organic chemistry 20040402

• SUMO modification of Huntingtin and Huntington's disease pathology.

  Science (New York, N.Y.) 20040402

• Asymmetric direct aldol reaction assisted by water and a proline-derived tetrazole catalyst.

  Angewandte Chemie (International ed. in English) 20040402

• [Effects of anti-sense Smad4 gene on the biological characteristics of the fat-storing cell line CFSC].

  Zhonghua yi xue za zhi 20040402

• Tyrosine agonists reverse the molecular defects associated with dominant-negative mutations in human peroxisome proliferator-activated receptor gamma.

  Endocrinology 20040401

• Proline residues in transmembrane segment IV are critical for activity, expression and targeting of the Na+/H+ exchanger isoform 1.

  The Biochemical journal 20040401

• Transport of pharmacologically active proline derivatives by the human proton-coupled amino acid transporter hPAT1.

  The Journal of pharmacology and experimental therapeutics 20040401

• The plasma membrane-bound phospholipase Ddelta enhances freezing tolerance in Arabidopsis thaliana.

  Nature biotechnology 20040401

• When defense pathways collide. The response of Arabidopsis to a combination of drought and heat stress.

  Plant physiology 20040401

• Conserved 'PAL' sequence in presenilins is essential for gamma-secretase activity, but not required for formation or stabilization of gamma-secretase complexes.

  Neurobiology of disease 20040401

• TWEAK can induce pro-inflammatory cytokines and matrix metalloproteinase-9 in macrophages.

  Circulation journal : official journal of the Japanese Circulation Society 20040401

• S-stereoselective piperazine-2-tert-butylcarboxamide hydrolase from Pseudomonas azotoformans IAM 1603 is a novel L-amino acid amidase.

  European journal of biochemistry 20040401

• A model of chronic heart failure in spontaneous hypertensive rats (SHR).

  Laboratory animals 20040401

• Low-proline environments impair growth, proline transport and in vivo survival of Staphylococcus aureus strain-specific putP mutants.

  Microbiology (Reading, England) 20040401

• Proline accumulation and AtP5CS2 gene activation are induced by plant-pathogen incompatible interactions in Arabidopsis.

  Molecular plant-microbe interactions : MPMI 20040401

• Pinning down cell signaling, cancer and Alzheimer's disease.

  Trends in biochemical sciences 20040401

• Hyperhomocysteinemia activates NF-kappaB and inducible nitric oxide synthase in the kidney.

  Kidney international 20040401

• [Effect of protein kinase C-nuclear factor-kappa B signal transduction pathway on proliferation and expression of vascular endothelial growth factor in human pulmonary artery smooth muscle cells].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20040401

• [Exogenous nitric oxide alleviates osmotic stress-induced membrane lipid peroxidation in wheat seedling leaves].

  Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20040401

• Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions.

  The Journal of biological chemistry 20040326

• Identification of a novel conserved motif in the STAT family that is required for tyrosine phosphorylation.

  The Journal of biological chemistry 20040326

• Structure of a hydroxyproline (Hyp)-arabinogalactan polysaccharide from repetitive Ala-Hyp expressed in transgenic Nicotiana tabacum.

  The Journal of biological chemistry 20040326

• Potential peptide carriers: amphipathic proline-rich peptides derived from the N-terminal domain of gamma-zein.

  Angewandte Chemie (International ed. in English) 20040326

• Structure-activity study on a novel series of macrocyclic inhibitors of the hepatitis C virus NS3 protease leading to the discovery of BILN 2061.

  Journal of medicinal chemistry 20040325

• A gating hinge in Na+ channels; a molecular switch for electrical signaling.

  Neuron 20040325

• Proton release and uptake of pharaonis phoborhodopsin (sensory rhodopsin II) reconstituted into phospholipids.

  Biochemistry 20040323

• Diastereoselective aldol reaction of N,N-dibenzyl-alpha-amino aldehydes with ketones catalyzed by proline.

  Organic letters 20040318

• Structure of the prolidase from Pyrococcus furiosus.

  Biochemistry 20040316

• Analysis of the substrate specificity loop of the HAD superfamily cap domain.

  Biochemistry 20040316

• A novel proteomic screen for peptide-protein interactions.

  The Journal of biological chemistry 20040312

• Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.

  The Journal of biological chemistry 20040312

• Enhancement of chemotherapeutic response of tumor cells by a heme oxygenase inhibitor, pegylated zinc protoporphyrin.

  International journal of cancer 20040301

• Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands.

  Journal of structural biology 20040301

• Mechanical stabilization of desiccated vegetative tissues of the resurrection grass Eragrostis nindensis: does a TIP 3;1 and/or compartmentalization of subcellular components and metabolites play a role?

  Journal of experimental botany 20040301

• Age-dependent changes of the periodontal ligament in rats.

  Microscopy research and technique 20040301

• Cycloanthranilylproline-derived constituents from a myxomycete Fuligo candida.

  Chemical & pharmaceutical bulletin 20040301

• A map of WW domain family interactions.

  Proteomics 20040301

• Association of a four-amino acid residue insertion polymorphism of the HS1 gene with systemic lupus erythematosus: molecular and functional analysis.

  Arthritis and rheumatism 20040301

• A twist code determines the onset of osteoblast differentiation.

  Developmental cell 20040301

• Biological activity of silylated amino acid containing substance P analogues.

  The journal of peptide research : official journal of the American Peptide Society 20040301

• PaASK1, a mitogen-activated protein kinase kinase kinase that controls cell degeneration and cell differentiation in Podospora anserina.

  Genetics 20040301

• Pharmacological and electrophysiological properties of the naturally occurring Pro391Arg variant of the human 5-HT3A receptor.

  Pharmacogenetics 20040301

• Arabidopsis transcriptional activators CBF1, CBF2, and CBF3 have matching functional activities.

  Plant molecular biology 20040301

• Quantitative observation of backbone disorder in native elastin.

  The Journal of biological chemistry 20040227

• Comparative vibrational spectroscopy of intracellular tau and extracellular collagen I reveals parallels of gelation and fibrillar structure.

  The Journal of biological chemistry 20040227

• The peptidyl prolyl cis/trans-isomerase Pin1 recognizes the phospho-Thr212-Pro213 site on Tau.

  Biochemistry 20040224

• Modulating calcitonin fibrillogenesis: an antiparallel alpha-helical dimer inhibits fibrillation of salmon calcitonin.

  The Journal of biological chemistry 20040220

• Ligand recognition and homophilic interactions in Tyro3: structural insights into the Axl/Tyro3 receptor tyrosine kinase family.

  The Journal of biological chemistry 20040220

• Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene.

  The Journal of biological chemistry 20040220

• Outer pore topology of the ECaC-TRPV5 channel by cysteine scan mutagenesis.

  The Journal of biological chemistry 20040220

• DsbB elicits a red-shift of bound ubiquinone during the catalysis of DsbA oxidation.

  The Journal of biological chemistry 20040220

• A conserved proline in the last transmembrane segment of Gaa1 is required for glycosylphosphatidylinositol (GPI) recognition by GPI transamidase.

  The Journal of biological chemistry 20040220

• Direct proline-catalyzed asymmetric alpha-aminoxylation of ketones.

  Angewandte Chemie (International ed. in English) 20040220

• The disassembly and reassembly of mutants of Escherichia coli heat-labile enterotoxin: replacement of proline 93 does not abolish the reassembly-competent and reassembly-incompetent states.

  Biochemistry 20040217

• Cation-pi interactions as determinants for binding of the compatible solutes glycine betaine and proline betaine by the periplasmic ligand-binding protein ProX from Escherichia coli.

  The Journal of biological chemistry 20040213

• An immunodominant epitope of myelin basic protein is an amphipathic alpha-helix.

  The Journal of biological chemistry 20040213

• Thermodynamic dissection of the binding energetics of proline-rich peptides to the Abl-SH3 domain: implications for rational ligand design.

  Journal of molecular biology 20040213

• Trypsin disrupts the trafficking of the human dopamine transporter by alpha-synuclein and its A30P mutant.

  Biochemistry 20040210

• Enzymatic mechanism of low-activity mouse alcohol dehydrogenase 2.

  Biochemistry 20040210

• Hydrophytes lack potential to exhibit cadmium stress induced enhancement in lipid peroxidation and accumulation of proline.

  Aquatic toxicology (Amsterdam, Netherlands) 20040210

• Effects of L- or D-Pro incorporation into hydrophobic or hydrophilic helix face of amphipathic alpha-helical model peptide on structure and cell selectivity.

  Biochemical and biophysical research communications 20040206

• Re: Integrin beta3 Leu33Pro homozygosity and risk of cancer.

  Journal of the National Cancer Institute 20040204

• Investigating the importance of the flexible hinge in caerin 1.1: solution structures and activity of two synthetically modified caerin peptides.

  Biochemistry 20040203

• PDTC, metal chelating compound, induces G1 phase cell cycle arrest in vascular smooth muscle cells through inducing p21Cip1 expression: involvement of p38 mitogen activated protein kinase.

  Journal of cellular physiology 20040201

• A novel missense mutation in the paired domain of PAX9 causes non-syndromic oligodontia.

  Human genetics 20040201

• Encapsulation of PROLI/NO in biodegradable microparticles.

  Journal of microencapsulation 20040201

• The cellular responses of articular cartilage to sharp and blunt trauma.

  Osteoarthritis and cartilage 20040201

• Overexpression of NtHAL3 genes confers increased levels of proline biosynthesis and the enhancement of salt tolerance in cultured tobacco cells.

  Journal of experimental botany 20040201

• Serotonin transporter and GABAA alpha 6 receptor variants are associated with neuroticism.

  Biological psychiatry 20040201

• Leucine 7 to proline 7 polymorphism in the preproneuropeptide Y is associated with proteinuria, coronary heart disease, and glycemic control in type 1 diabetic patients.

  Diabetes care 20040201

• Influence of the polymorphisms Tpr64Arg in the beta 3-adrenergic receptor gene and Pro12Ala in the PPAR gamma 2 gene on metabolic syndrome-related phenotypes in an indigenous population of the Brazilian Amazon.

  Diabetes care 20040201

• Polyproline II helix conformation in a proline-rich environment: a theoretical study.

  Biophysical journal 20040201

• Structure of the core region of the soybean beta-conglycinin alpha' subunit.

  Acta crystallographica. Section D, Biological crystallography 20040201

• Synthesis of interkeratin matrix in differentiating lizard epidermis: an ultrastructural autoradiographic study after injection of tritiated proline and histidine.

  Journal of morphology 20040201

• The metabolic response to ingestion of proline with and without glucose.

  Metabolism: clinical and experimental 20040201

• Four permeases import proline and the toxic proline analogue azetidine-2-carboxylate into yeast.

  Yeast (Chichester, England) 20040201

• A novel highly pathogenic Alzheimer presenilin-1 mutation in codon 117 (Pro117Ser): Comparison of clinical, neuropathological and cell culture phenotypes of Pro117Leu and Pro117Ser mutations.

  Journal of Alzheimer's disease : JAD 20040201

• Laminar shear stress up-regulates inducible nitric oxide synthase in the endothelium.

  Hypertension research : official journal of the Japanese Society of Hypertension 20040201

• Biological and conformational study of beta-substituted prolines in MT-II template: steric effects leading to human MC5 receptor selectivity.

  The journal of peptide research : official journal of the American Peptide Society 20040201

• A new mutation in the hepatocyte nuclear factor-1-alpha gene (P224S) in a newly discovered German family with maturity-onset diabetes of the young 3 (MODY 3). Family members carry additionally the homozygous I27L amino acid polymorphism in the HNF1 alpha gene.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20040201

• Distribution of proline-rich (PxxP) motifs in distinct proteomes: functional and therapeutic implications for malaria and tuberculosis.

  Protein engineering, design & selection : PEDS 20040201

• Structure and fungicidal activity of a synthetic antimicrobial peptide, P18, and its truncated peptides.

  Biotechnology letters 20040201

• Development of co-culture system of hepatocytes with bone marrow cells for expression and maintenance of hepatic functions.

  The International journal of artificial organs 20040201

• [Increase in the level of proline and osmotic pressure of cytoplasm in transformed tobacco bearing an antisense suppressor of the proline dehydrogenase gene].

  Genetika 20040201

• Identification and characterization of a nitrate transporter gene in Neurospora crassa.

  Biochemical genetics 20040201

• Artifactually elevated serum-free thyroxine levels measured by equilibrium dialysis in a pregnant woman with familial dysalbuminemic hyperthyroxinemia.

  Thyroid : official journal of the American Thyroid Association 20040201

• A comparison study of gastric cancer risk in patients with duodenal and gastric ulcer: roles of gastric mucosal histology and p53 codon 72 polymorphism.

  Digestive diseases and sciences 20040201

• [Changes in solute content of different tomato genotypes under salt stress].

  Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20040201

• Improving protein pharmacokinetics by genetic fusion to simple amino acid sequences.

  The Journal of biological chemistry 20040130

• Unexpectedly fast cis/trans isomerization of Xaa-Pro peptide bonds in disulfide-constrained cyclic peptides.

  Journal of the American Chemical Society 20040128

• Overcoming the toxicity of membrane peptide expression in bacteria by upstream insertion of Asp-Pro sequence.

  Biochimica et biophysica acta 20040128

• Reactions of 4-oxalocrotonate tautomerase and YwhB with 3-halopropiolates: analysis and implications.

  Biochemistry 20040127

• Cloning, expression, and characterization of a cis-3-chloroacrylic acid dehalogenase: insights into the mechanistic, structural, and evolutionary relationship between isomer-specific 3-chloroacrylic acid dehalogenases.

  Biochemistry 20040127

• Interactions at the dimer interface influence the relative efficiencies for purine nucleotide synthesis and pyrophosphorolysis in a phosphoribosyltransferase.

  Journal of molecular biology 20040123

• Snapshots of DsbA in action: detection of proteins in the process of oxidative folding.

  Science (New York, N.Y.) 20040123

• An atypical topoisomerase II sequence from the slime mold Physarum polycephalum.

  Gene 20040121

• Chloride complexation by heptapeptides: influence of C- and N-terminal sidechains and counterion.

  Chemical communications (Cambridge, England) 20040121

• Mapping abeta amyloid fibril secondary structure using scanning proline mutagenesis.

  Journal of molecular biology 20040116

• A novel nuclear localization signal in the human single-minded proteins SIM1 and SIM2.

  Biochemical and biophysical research communications 20040116

• Restriction of a peptide turn conformation and conformational analysis of guanidino group using arginine-proline fused amino acids: application to mini atrial natriuretic peptide on binding to the receptor.

  Journal of medicinal chemistry 20040115

• High affinity, paralog-specific recognition of the Mena EVH1 domain by a miniature protein.

  Journal of the American Chemical Society 20040114

• p53 polymorphic variants at codon 72 exert different effects on cell cycle progression.

  International journal of cancer 20040110

• Influence of proline residues in transmembrane helix packing.

  Journal of molecular biology 20040109

• Discovery of a novel bicycloproline P2 bearing peptidyl alpha-ketoamide LY514962 as HCV protease inhibitor.

  Bioorganic & medicinal chemistry letters 20040105

• P1 and P3 optimization of novel bicycloproline P2 bearing tetrapeptidyl alpha-ketoamide based HCV protease inhibitors.

  Bioorganic & medicinal chemistry letters 20040105

• Proline-directed random-coil chemical shift values as a tool for the NMR assignment of the tau phosphorylation sites.

  Chembiochem : a European journal of chemical biology 20040103

• A (4R)- or a (4S)-fluoroproline residue in position Xaa of the (Xaa-Yaa-Gly) collagen repeat severely affects triple-helix formation.

  Chembiochem : a European journal of chemical biology 20040103

• The peptides acetyl-(Gly-3(S)Hyp-4(R)Hyp)10-NH2 and acetyl-(Gly-Pro-3(S)Hyp)10-NH2 do not form a collagen triple helix.

  The Journal of biological chemistry 20040102

• Position of Pro and Ser near Glu7.32 in the extracellular loop 3 of mammalian and nonmammalian gonadotropin-releasing hormone (GnRH) receptors is a critical determinant for differential ligand selectivity for mammalian GnRH and chicken GnRH-II.

  Molecular endocrinology (Baltimore, Md.) 20040101

• Overexpression of decorin by rat arterial smooth muscle cells enhances contraction of type I collagen in vitro.

  Arteriosclerosis, thrombosis, and vascular biology 20040101

• The effect of step-wise increased stretching on rat calvarial osteoblast collagen production.

  Journal of biomechanics 20040101

• Role of proline residues in the expression and function of the human noradrenaline transporter.

  Journal of neurochemistry 20040101

• Does peroxisome proliferator-activated receptor gamma genotype (Pro12ala) modify the association of physical activity and dietary fat with fasting insulin level?

  Metabolism: clinical and experimental 20040101

• Plant-dependent active biological containment system for recombinant rhizobacteria.

  Environmental microbiology 20040101

• Identification of in vivo pellicle constituents by analysis of serum immune responses.

  Journal of dental research 20040101

• Ser and Thr residues modulate the conformation of pro-kinked transmembrane alpha-helices.

  Biophysical journal 20040101

• NMR structural characterization of peptide inhibitors bound to the Hepatitis C virus NS3 protease: design of a new P2 substituent.

  Journal of medicinal chemistry 20040101

• Endotoxin releases a precursor to vasodilation from large veins in an NF-kappaB-dependent manner.

  The Journal of surgical research 20040101

• Imaging of gliomas with Cis-4-[18F]fluoro-L-proline.

  Nuclear medicine and biology 20040101

• Ab initio calculations of proton affinities of glycine, proline, cysteine and phenylalanine: comparison with the experimental values obtained using an electrospray ionisation ion trap mass spectrometer.

  Rapid communications in mass spectrometry : RCM 20040101

• Effects of the hydroxyl radical and hydrogen peroxide on tooth bleaching.

  Journal of endodontics 20040101

• Support vector machines for prediction of peptidyl prolyl cis/trans isomerization.

  The journal of peptide research : official journal of the American Peptide Society 20040101

• Spinal phenotype of cerebrotendinous xanthomatosis--a pitfall in the diagnosis of multiple sclerosis.

  Journal of neurology 20040101

• A model for the role of the proline-linked pentose-phosphate pathway in phenolic phytochemical bio-synthesis and mechanism of action for human health and environmental applications.

  Asia Pacific journal of clinical nutrition 20040101

• An Aneurinibacillus sp. strain AM-1 produces a proline-specific aminopeptidase useful for collagen degradation.

  Journal of applied microbiology 20040101

• Kinetics of asparaginase II fermentation in Saccharomyces cerevisiae ure2dal80 mutant: effect of nitrogen nutrition and pH.

  Applied biochemistry and biotechnology 20040101

• Transgenic tobacco plants accumulating osmolytes show reduced oxidative damage under freezing stress.

  Plant physiology and biochemistry : PPB 20040101

• Polyamine, carbohydrate, and proline content changes during salt stress exposure of aspen (Populus tremula L.): involvement of oxidation and osmoregulation metabolism.

  Plant biology (Stuttgart, Germany) 20040101

• Overlapping motifs in the membrane-proximal region of cytokine receptor accessory and signaling subunits.

  Cytokine & growth factor reviews 20040101

• The epithelial sodium channel: from molecule to disease.

  Reviews of physiology, biochemistry and pharmacology 20040101

• A novel zinc-finger protein with a proline-rich domain mediates ABA-regulated seed dormancy in Arabidopsis.

  Plant molecular biology 20040101

• Type II hyperprolinemia: a case report.

  The Turkish journal of pediatrics 20040101

• Selected cyclic dipeptides inhibit cancer cell growth and induce apoptosis in HT-29 colon cancer cells.

  Anticancer research 20040101

• Congenital methaemoglobinaemia Type I in a Turkish infant due to a novel mutation, Pro144Ser, in NADH-cytochrome b5 reductase.

  The hematology journal : the official journal of the European Haematology Association 20040101

• The influence of oxygen and hydrostatic pressure on articular chondrocytes and adherent bone marrow cells in vitro.

  Biorheology 20040101

• Effect of molecular crowding on self-association of phosphorylase kinase and its interaction with phosphorylase b and glycogen.

  Journal of molecular recognition : JMR 20040101

• Crystal structures of collagen model peptides with Pro-Hyp-Gly repeating sequence at 1.26 A resolution: implications for proline ring puckering.

  Biopolymers 20040101

• Effects of single amino acid substitution on the collision-induced dissociation of intact protein ions: Turkey ovomucoid third domain.

  Journal of proteome research 20040101

• [Pharmacokinetics of glyprolines (PGP) upon intragastric administration].

  Eksperimental'naia i klinicheskaia farmakologiia 20040101

• Computational approach to solvent-free synthesis of ethyl oleate using Candida rugosa and Candida antarctica B Lipases. I. Interfacial activation and substrate (ethanol, oleic acid) adsorption.

  Biomacromolecules 20040101

• [Antiulcer effects of the tripeptide PGP and its possible metabolites (PG, GP, glycine, and proline) in different models of ulcer induction in rats].

  Izvestiia Akademii nauk. Seriia biologicheskaia 20040101

• Water stress induces changes in the proline content and up-regulates the activities of anti-oxidant enzymes in tomato leaves.

  Communications in agricultural and applied biological sciences 20040101

• [Protective effect of the intraperitoneal and intragastric administration of PGP-peptide on ethanol-induced erosions and acetate-induced ulcers in rats].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20040101

• The frequency of alleles of the Pro12Ala polymorphism in PPARgamma2 is different between healthy controls and patients with type 2 diabetes.

  Folia biologica 20040101

• 2R,4R-APDC influence on hypoxia-induced impairment of learning and memory processes in passive avoidance test.

  Polish journal of pharmacology 20040101

• Association between transforming growth factor beta1 gene polymorphisms and IgA nephropathy.

  Journal of nephrology 20040101

• Association of TGF-beta1 polymorphisms with chronic renal disease.

  Journal of nephrology 20040101

• Molecular characterization and diagnosis of Hb Crete [beta129(H7)Ala-->Pro].

  Hemoglobin 20040101

• Quantification of the particle method for chemotactic bioassay using Peronosporomycete zoospores.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

• [Simultaneous determination of amino acids in food by capillary electrophoresis with indirect ultraviolet detection].

  Se pu = Chinese journal of chromatography 20040101

• [Usefulness of D-proline in the differentiation of varieties of Cryptococcus neoformans].

  Revista cubana de medicina tropical 20040101

• Anti-tumor effect of ascorbic acid, lysine, proline, arginine, and epigallocatechin gallate on prostate cancer cell lines PC-3, LNCaP, and DU145.

  Research communications in molecular pathology and pharmacology 20040101

• An isolated class II aminoacyl-tRNA synthetase insertion domain is functional in amino acid editing.

  The Journal of biological chemistry 20031226

• Regulation of SPIN90 phosphorylation and interaction with Nck by ERK and cell adhesion.

  The Journal of biological chemistry 20031226

• Isolation and characterisation of proline/arginine-rich cathelicidin peptides from ovine neutrophils.

  Biochemical and biophysical research communications 20031226

• Conformational behavior of beta-proline oligomers.

  Journal of the American Chemical Society 20031224

• Estimation of the potential for nitrosation and its inhibition in subjects from high- and low-risk areas for esophageal cancer in southern China.

  International journal of cancer 20031220

• Protease-activated receptor-4 uses dual prolines and an anionic retention motif for thrombin recognition and cleavage.

  The Biochemical journal 20031215

• Gating of shaker-type channels requires the flexibility of S6 caused by prolines.

  The Journal of biological chemistry 20031212

• The nature of the rate-limiting steps in the refolding of the cofactor-dependent protein aspartate aminotransferase.

  The Journal of biological chemistry 20031212

• The direct organocatalytic asymmetric mannich reaction: unmodified aldehydes as nucleophiles.

  The Journal of organic chemistry 20031212

• N-tritylprolinal: an efficient building block for the stereoselective synthesis of proline-derived amino alcohols.

  The Journal of organic chemistry 20031212

• What is so special about Arg 55 in the catalysis of cyclophilin A? insights from hybrid QM/MM simulations.

  Journal of the American Chemical Society 20031210

• Cathelicidin family of antimicrobial peptides: proteolytic processing and protease resistance.

  Bioorganic chemistry 20031201

• Alpha-substituted hydroxamic acids as novel bacterial deformylase inhibitor-based antibacterial agents.

  Bioorganic & medicinal chemistry letters 20031201

• IGF-I and MAP kinase involvement in the stimulatory effects of LNCaP prostate cancer cell conditioned media on cell proliferation and protein synthesis in MC3T3-E1 osteoblastic cells.

  Journal of cellular biochemistry 20031201

• Role of extracellular matrix in insulin-like growth factor (IGF) binding protein-2 regulation of IGF-II action in normal human osteoblasts.

  Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20031201

• Ammonia cleaves polypeptides at asparagine proline bonds.

  The journal of peptide research : official journal of the American Peptide Society 20031201

• Thermodynamic effects of replacements of Pro residues in helix interiors of maltose-binding protein.

  Proteins 20031201

• Synthesis, conformation, and immunosuppressive activity of CLX and its analogues.

  Biopolymers 20031201

• Perturbation of folding and reassociation of lactate dehydrogenase by proline and trimethylamine oxide.

  European journal of biochemistry 20031201

• Solution structure and stability of the full-length excisionase from bacteriophage HK022.

  European journal of biochemistry 20031201

• VARICOSE, a WD-domain protein, is required for leaf blade development.

  Development (Cambridge, England) 20031201

• Direct inhibition of neutral endopeptidase in vasopeptidase inhibitor-mediated amelioration of cardiac remodeling in rats with chronic heart failure.

  Molecular and cellular biochemistry 20031201

• Metabolic stability, receptor binding, cAMP generation, insulin secretion and antihyperglycaemic activity of novel N-terminal Glu9-substituted analogues of glucagon-like peptide-1.

  Biological chemistry 20031201

• Cryopreservation of the unicellular marine alga, Nannochloropsis oculata.

  Biotechnology letters 20031201

• Proline versus charge concept for protein stabilization against proteolytic attack.

  Protein engineering 20031201

• Hepatic amyloidosis resulting from deposition of the apolipoprotein A-I variant Leu75Pro.

  Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20031201

• NF-kappaB inhibition restores sensitivity to Fas-mediated apoptosis in lymphoma cell lines.

  Annals of the New York Academy of Sciences 20031201

• Spatial approximation between two residues in the mid-region of secretin and the amino terminus of its receptor. Incorporation of seven sets of such constraints into a three-dimensional model of the agonist-bound secretin receptor.

  The Journal of biological chemistry 20031128

• Modification of 1-substituents in the 2-azabicyclo[2.1.1]hexane ring system; approaches to potential nicotinic acetylcholine receptor ligands from 2,4-methanoproline derivatives.

  The Journal of organic chemistry 20031128

• Amyloid fibril formation in the context of full-length protein: effects of proline mutations on the amyloid fibril formation of beta2-microglobulin.

  The Journal of biological chemistry 20031121

• In vivo and in vitro effects of proline on some parameters of oxidative stress in rat brain.

  Brain research 20031121

• Application of HN(C)N to rapid estimation of 1J(N-C(alpha)) coupling constants correlated to psi torsion angles in proteins: implication to structural genomics.

  Biochemical and biophysical research communications 20031121

• The contribution of proline 250 (P-2') to pore diameter and ion selectivity in the human glycine receptor channel.

  Neuroscience letters 20031120

• The structure of the S127P mutant of cytochrome b5 reductase that causes methemoglobinemia shows the AMP moiety of the flavin occupying the substrate binding site.

  Biochemistry 20031118

• Dissection of human tropoelastin: exon-by-exon chemical synthesis and related conformational studies.

  Biochemistry 20031118

• Interaction between a peroxisome proliferator-activated receptor gamma gene polymorphism and dietary fat intake in relation to body mass.

  Human molecular genetics 20031115

• Fatal hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection in a patient with a novel mutation in the signaling lymphocytic activation molecule-associated protein.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20031115

• Concerted regulation of cell dynamics by BNIP-2 and Cdc42GAP homology/Sec14p-like, proline-rich, and GTPase-activating protein domains of a novel Rho GTPase-activating protein, BPGAP1.

  The Journal of biological chemistry 20031114

• PACSIN3 binds ADAM12/meltrin alpha and up-regulates ectodomain shedding of heparin-binding epidermal growth factor-like growth factor.

  The Journal of biological chemistry 20031114

• Factors affecting conformation in proline-containing peptides.

  Organic letters 20031113

• Monitoring the early steps of unfolding of dicalcium and mono-Ce3+-substituted forms of P43M calbindin D9k.

  Biochemistry 20031111

• Synthesis and evaluation of chiral bicyclic proline FKBP12 ligands.

  Bioorganic & medicinal chemistry letters 20031103

• Synthesis, molecular modeling and biological evaluation of aza-proline and aza-pipecolic derivatives as FKBP12 ligands and their in vivo neuroprotective effects.

  Bioorganic & medicinal chemistry 20031103

• Regional differences in water content, collagen content, and collagen degradation in the cervix of nonpregnant cows.

  Biology of reproduction 20031101

• NF-kappaB in critical diseases: a bad guy?

  Intensive care medicine 20031101

• Proline induces the expression of salt-stress-responsive proteins and may improve the adaptation of Pancratium maritimum L. to salt-stress.

  Journal of experimental botany 20031101

• Vascularization, high-volume solution flow, and localized roles for enzymes of sucrose metabolism during tumorigenesis by Agrobacterium tumefaciens.

  Plant physiology 20031101

• PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis.

  Nature neuroscience 20031101

• Extensive structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5.

  The journal of peptide research : official journal of the American Peptide Society 20031101

• Using protein-based motifs to stabilize peptides.

  The journal of peptide research : official journal of the American Peptide Society 20031101

• Proline analogue of melphalan as a prodrug susceptible to the action of prolidase in breast cancer MDA-MB 231 cells.

  Farmaco (Societa chimica italiana : 1989) 20031101

• A missense mutation in the SH3BP2 gene on chromosome 4p16.3 found in a case of nonfamilial cherubism.

  The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 20031101

• The Pro12Ala polymorphism of PPARgamma2 gene and susceptibility to type 2 diabetes mellitus in a Polish population.

  Diabetes research and clinical practice 20031101

• Metabotropic glutamate receptor regulation of neuronal cell death.

  Experimental neurology 20031101

• P301L Tau mutation and non-Alzheimer dementias in Italy.

  Acta neurologica Scandinavica 20031101

• Stabilization of a chitinase from Serratia marcescens by Gly-->Ala and Xxx-->Pro mutations.

  Protein engineering 20031101

• [Of protein kinases involved in nutrient signaling in plants].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20031101

• Brain amino acid abnormalities in liver disease--a postmortem study.

  Journal of forensic sciences 20031101

• Protection of mitochondrial perturbation by human T-lymphotropic virus type 1 tax through induction of Bcl-xL expression.

  The Journal of laboratory and clinical medicine 20031101

• Prefrontal group II metabotropic glutamate receptor activation decreases performance on a working memory task.

  Annals of the New York Academy of Sciences 20031101

• Bidirectional modulation of cystine/glutamate exchanger activity in cultured cortical astrocytes.

  Annals of the New York Academy of Sciences 20031101

• A novel missense mutation of the MEN1 gene in a multiple endocrine neoplasia type 1 patient associated with carcinoid syndrome.

  Internal medicine (Tokyo, Japan) 20031101

• Glyprolines and semax prevent stress-induced microcirculatory disturbances in the mesentery.

  Bulletin of experimental biology and medicine 20031101

• Neuromodulatory mechanism underlying the effect of the atypical dipeptide neuroleptic dilept.

  Bulletin of experimental biology and medicine 20031101

• [Physiological response to salt-alkali stress in experimental populations in two ecotypes of Leymus chinensis in the Songnen Plains of China].

  Ying yong sheng tai xue bao = The journal of applied ecology 20031101

• Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression.

  The Journal of biological chemistry 20031031

• Structural characterization of the HIV-1 Vpr N terminus: evidence of cis/trans-proline isomerism.

  The Journal of biological chemistry 20031031

• Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I.

  The Journal of biological chemistry 20031031

• Transmembrane domain II of the Na+/proline transporter PutP of Escherichia coli forms part of a conformationally flexible, cytoplasmic exposed aqueous cavity within the membrane.

  The Journal of biological chemistry 20031031

• Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles.

  Neuron 20031030

• Interaction between extracellular Hanatoxin and the resting conformation of the voltage-sensor paddle in Kv channels.

  Neuron 20031030

• Asymmetric synthesis of unsaturated, fused bicyclic proline analogues through amino alkylation of cyclic bis(allylsulfoximine)titanium complexes and migratory cyclization of delta-amino alkenyl aminosulfoxonium salts.

  Journal of the American Chemical Society 20031029

• A binding event converted into a folding event.

  FEBS letters 20031023

• Two prolines with a difference: contrasting stereoelectronic effects of 4R/S-aminoproline on triplex stability in collagen peptides [pro(X)-pro(Y)-Gly]n.

  Chemical communications (Cambridge, England) 20031021

• Trichohyalin mechanically strengthens the hair follicle: multiple cross-bridging roles in the inner root shealth.

  The Journal of biological chemistry 20031017

• Targeting and assembly of mitochondrial tail-anchored protein Tom5 to the TOM complex depend on a signal distinct from that of tail-anchored proteins dispersed in the membrane.

  The Journal of biological chemistry 20031017

• Protein-tyrosine phosphatase 1B mediates the effects of insulin on the actin cytoskeleton in immortalized fibroblasts.

  The Journal of biological chemistry 20031017

• GPVI levels in platelets: relationship to platelet function at high shear.

  Blood 20031015

• The conserved cis-Pro39 residue plays a crucial role in the proper positioning of the catalytic base Asp38 in ketosteroid isomerase from Comamonas testosteroni.

  The Biochemical journal 20031015

• Analysis of the isomeric composition of the proline peptide bond in an angiotensin-converting enzyme inhibitor using capillary electrophoresis.

  Analytical biochemistry 20031015

• Retention of the p53 codon 72 arginine allele is associated with a reduction of disease-free and overall survival in arginine/proline heterozygous breast cancer patients.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20031015

• Probing hydrogen-bonding interactions in the active site of medium-chain acyl-CoA dehydrogenase using Raman spectroscopy.

  Biochemistry 20031014

• [Familial hypocalciuric hypercalcemia].

  Orvosi hetilap 20031012

• Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors.

  The Journal of biological chemistry 20031010

• New prolyl oligopeptidase inhibitors developed from dicarboxylic acid bis(l-prolyl-pyrrolidine) amides.

  Journal of medicinal chemistry 20031009

• Proline-catalysed asymmetric amination of alpha,alpha-disubstituted aldehydes: synthesis of configurationally stable enantioenriched alpha-aminoaldehydes.

  Chemical communications (Cambridge, England) 20031007

• A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice.

  The Journal of biological chemistry 20031003

• Inhibition of glutamine synthetase in the mouse kidney: a novel mechanism of adaptation to metabolic acidosis.

  The Journal of biological chemistry 20031003

• Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation.

  The Journal of biological chemistry 20031003

• Indolicidin, a 13-residue basic antimicrobial peptide rich in tryptophan and proline, interacts with Ca(2+)-calmodulin.

  Biochemical and biophysical research communications 20031003

• Dual catalyst control in the amino acid-peptide-catalyzed enantioselective Baylis-Hillman reaction.

  Organic letters 20031002

• Structural investigations of a GYF domain covalently linked to a proline-rich peptide.

  Journal of biomolecular NMR 20031001

• Stress reactions in Vitis vinifera L. following soil application of the herbicide flumioxazin.

  Chemosphere 20031001

• Evidence that oxidative stress is involved in the inhibitory effect of proline on Na(+),K(+)-ATPase activity in synaptic plasma membrane of rat hippocampus.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20031001

• Allosteric modulation of a neuronal K+ channel by 1-alkanols is linked to a key residue in the activation gate.

  American journal of physiology. Cell physiology 20031001

• Salivary gland function in persons with ectodermal dysplasias.

  European journal of oral sciences 20031001

• Detection of four oxidation sites in viral prolyl-4-hydroxylase by top-down mass spectrometry.

  Protein science : a publication of the Protein Society 20031001

• Peptide self-replication enhanced by a proline kink.

  Journal of the American Chemical Society 20031001

• Multiple GATA sites: protein binding and physiological relevance for the regulation of the proline transporter gene of Aspergillus nidulans.

  Molecular microbiology 20031001

• Prospective study of the association between the proline to alanine codon 12 polymorphism in the PPARgamma gene and type 2 diabetes.

  Diabetes care 20031001

• Missense mutation of Pro387Leu in protein tyrosine phosphatase-1B (PTP-1B) is not associated with type 2 diabetes in a Chinese Han population.

  Diabetes care 20031001

• Modulation of transcription factor function by an amino acid: activation of Put3p by proline.

  The EMBO journal 20031001

• A conserved catalytic residue in the ubiquitin-conjugating enzyme family.

  The EMBO journal 20031001

• Characterization of cereal toxicity for celiac disease patients based on protein homology in grains.

  Gastroenterology 20031001

• Selective opening of the blood-tumor barrier by a nitric oxide donor and long-term survival in rats with C6 gliomas.

  Journal of neurosurgery 20031001

• Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: a meta-analysis.

  Journal of medical genetics 20031001

• A role of P301L tau mutant in anti-apoptotic gene expression, cell cycle and apoptosis.

  Molecular and cellular neurosciences 20031001

• Polymorphism of the p53 codon 72 Arg/Pro and the risk of HPV type 16/18-associated cervical and oral cancer in India.

  Molecular and cellular biochemistry 20031001

• The association of Pro12Ala polymorphism in PPARgamma2 with lower carotid artery IMT in Japanese.

  Diabetes research and clinical practice 20031001

• Deciphering the molecular basis of the broad substrate specificity of alpha-glucosidase from Bacillus sp. SAM1606.

  Journal of biochemistry 20031001

• Secretory activity of mast cell during stress: effect of prolyl-glycyl-proline and Semax.

  Bulletin of experimental biology and medicine 20031001

• Triple-helix propensity of hydroxyproline and fluoroproline: comparison of host-guest and repeating tripeptide collagen models.

  Journal of the American Chemical Society 20030924

• Impact of proline residues on parvalbumin stability.

  Biochemistry 20030923

• Effect of proline to alanine mutation on the thermal stability of the all-beta-sheet protein tendamistat.

  Biochimica et biophysica acta 20030923

• Solution structure of the recombinant penaeidin-3, a shrimp antimicrobial peptide.

  The Journal of biological chemistry 20030919

• Delineation of the region in the glycoprotein VI tail required for association with the Fc receptor gamma-chain.

  The Journal of biological chemistry 20030919

• Functional analysis of RF2a, a rice transcription factor.

  The Journal of biological chemistry 20030919

• Design of N-substituted peptomer ligands for EVH1 domains.

  The Journal of biological chemistry 20030919

• Synthesis of functionally diverse and conformationally constrained polycyclic analogues of proline and prolinol.

  The Journal of organic chemistry 20030919

• Studies on the synthesis of (2S,3R)-3-hydroxy-3-methylproline via C2-N bond formation.

  The Journal of organic chemistry 20030919

• A mechanistically guided design leads to the synthesis of an efficient and practical new reagent for the highly enantioselective, catalytic dihydroxylation of olefins.

  Organic letters 20030918

• Synthesis of an oxazoline analogue of apratoxin A.

  Organic letters 20030918

• A proline-rich domain in the gamma subunit of phosphodiesterase 6 mediates interaction with SH3-containing proteins.

  Molecular vision 20030918

• Mechanisms of redox-coupled proton transfer in proteins: role of the proximal proline in reactions of the [3Fe-4S] cluster in Azotobacter vinelandii ferredoxin I.

  Biochemistry 20030916

• Malleable conformation of the elastic PEVK segment of titin: non-co-operative interconversion of polyproline II helix, beta-turn and unordered structures.

  The Biochemical journal 20030915

• The peptide-substrate-binding domain of human collagen prolyl 4-hydroxylases. Backbone assignments, secondary structure, and binding of proline-rich peptides.

  The Journal of biological chemistry 20030912

• A dynamic constitutive and inducible binding of c-Cbl by PLCgamma1 SH3 and SH2 domains (negatively) regulates antigen receptor-induced PLCgamma1 activation in lymphocytes.

  Experimental cell research 20030910

• The direct and enantioselective organocatalytic alpha-oxidation of aldehydes.

  Journal of the American Chemical Society 20030910

• GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2.

  The Journal of biological chemistry 20030905

• Proline365 is a critical residue for the activity of XMI-ER1 in Xenopus embryonic development.

  Biochemical and biophysical research communications 20030905

• Improved synthesis of proline-derived Ni(II) complexes of glycine: versatile chiral equivalents of nucleophilic glycine for general asymmetric synthesis of alpha-amino acids.

  The Journal of organic chemistry 20030905

• Impact of transport processes in the osmotic response of Corynebacterium glutamicum.

  Journal of biotechnology 20030904

• Mutation of proline residues in the NH(2)-terminal region of the multidrug resistance protein, MRP1 (ABCC1): effects on protein expression, membrane localization, and transport function.

  Biochimica et biophysica acta 20030902

• Decrease in activity of smooth muscle L-type Ca2+ channels and its reversal by NF-kappaB inhibitors in Crohn's colitis model.

  American journal of physiology. Gastrointestinal and liver physiology 20030901

• Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030901

• Development and structure of drought-tolerant leaves of the Mediterranean shrub Capparis spinosa L.

  Annals of botany 20030901

• Physiological aspects of vetiver grass for rehabilitation in abandoned metalliferous mine wastes.

  Chemosphere 20030901

• Intrinsically unstructured proteins evolve by repeat expansion.

  BioEssays : news and reviews in molecular, cellular and developmental biology 20030901

• Physical properties of type I collagen extracted from fish scales of Pagrus major and Oreochromis niloticas.

  International journal of biological macromolecules 20030901

• Protein kinase C epsilon-dependent activation of proline-rich tyrosine kinase 2 in neonatal rat ventricular myocytes.

  Journal of molecular and cellular cardiology 20030901

• A simple and low-cost electrochemiluminescence detector for capillary electrophoresis.

  Electrophoresis 20030901

• Highly water-soluble derivatives of the anesthetic agent propofol: in vitro and in vivo evaluation of cyclic amino acid esters.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030901

• Transport of proline and hydroxyproline by the neutral amino-acid exchanger ASCT1.

  The Journal of membrane biology 20030901

• Inhibition of NF-kB renders cells more vulnerable to apoptosis induced by amyloid beta peptides.

  Free radical research 20030901

• [Eco-physiological responses of Picea mongolica ecotypes to drought stress].

  Ying yong sheng tai xue bao = The journal of applied ecology 20030901

• Comparison of soluble decoy IgG fusion proteins of BAFF-R and BCMA as antagonists for BAFF.

  The Journal of biological chemistry 20030829

• A proline switch controls folding and domain interactions in the gene-3-protein of the filamentous phage fd.

  Journal of molecular biology 20030829

• Stereospecific interactions of proline residues in protein structures and complexes.

  Journal of molecular biology 20030822

• Characterization of collagen model peptides containing 4-fluoroproline; (4(S)-fluoroproline-pro-gly)10 forms a triple helix, but (4(R)-fluoroproline-pro-gly)10 does not.

  Journal of the American Chemical Society 20030820

• Native state proline isomerization: an intrinsic molecular switch.

  Biochemistry 20030819

• Auxin action in a cell-free system.

  Current biology : CB 20030819

• A novel role for FAK as a protease-targeting adaptor protein: regulation by p42 ERK and Src.

  Current biology : CB 20030819

• Design and synthesis of potent and selective macrocyclic thrombin inhibitors.

  Bioorganic & medicinal chemistry letters 20030818

• Transforming growth factor-beta1 gene polymorphisms are associated with disease progression in idiopathic pulmonary fibrosis.

  American journal of respiratory and critical care medicine 20030815

• Role of proline residues in the folding of serine hydroxymethyltransferase.

  The Journal of biological chemistry 20030815

• Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor.

  The Journal of biological chemistry 20030815

• Novel inhibitor for prolyl aminopeptidase from Serratia marcescens and studies on the mechanism of substrate recognition of the enzyme using the inhibitor.

  Archives of biochemistry and biophysics 20030815

• Catalytic oxidation of acetaminophen by tyrosinase in the presence of L-proline: a kinetic study.

  Archives of biochemistry and biophysics 20030815

• Genetic factors in idiopathic pulmonary fibrosis: transforming growth factor-beta implicated at last.

  American journal of respiratory and critical care medicine 20030815

• In vitro nutritional requirements and metabolic products of pathogenic and nonpathogenic strains of Cryptobia salmositica: essential carbohydrates and amino acids.

  Diseases of aquatic organisms 20030815

• Prolyl hydroxylation of collagen type I is required for efficient binding to integrin alpha 1 beta 1 and platelet glycoprotein VI but not to alpha 2 beta 1.

  The Journal of biological chemistry 20030808

• The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1.

  The Journal of biological chemistry 20030808

• Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK.

  The Journal of biological chemistry 20030808

• The functional integrity of the serpin domain of C1-inhibitor depends on the unique N-terminal domain, as revealed by a pathological mutant.

  The Journal of biological chemistry 20030808

• Nucleation of beta-hairpin structures with cis amide bonds in E-vinylogous proline-containing peptides.

  The Journal of organic chemistry 20030808

• Stereoelectronic effects on collagen stability: the dichotomy of 4-fluoroproline diastereomers.

  Journal of the American Chemical Society 20030806

• Integrin beta3 Leu33Pro homozygosity and risk of cancer.

  Journal of the National Cancer Institute 20030806

• Detection of in vivo genotoxicity of endogenously formed N-nitroso compounds and suppression by ascorbic acid, teas and fruit juices.

  Mutation research 20030805

• Discovery of new peptide-based catalysts for the direct asymmetric aldol reaction.

  Bioorganic & medicinal chemistry letters 20030804

• CloN6, a novel methyltransferase catalysing the methylation of the pyrrole-2-carboxyl moiety of clorobiocin.

  Chembiochem : a European journal of chemical biology 20030804

• Structure-expression relationship of tumor necrosis factor receptor mutants that increase expression.

  The Journal of biological chemistry 20030801

• The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates its intracellular distribution.

  The Journal of biological chemistry 20030801

• Stress effects of flumioxazin herbicide on grapevine ( Vitis vinifera L.) grown in vitro.

  Plant cell reports 20030801

• Conformation of the transmembrane domains in peripheral myelin protein 22. Part 1. Solution-phase synthesis and circular dichroism study of protected 17-residue partial peptides in the first putative transmembrane domain.

  The journal of peptide research : official journal of the American Peptide Society 20030801

• Proline reduces creatine kinase activity in the brain cortex of rats.

  Neurochemical research 20030801

• Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation.

  Traffic (Copenhagen, Denmark) 20030801

• A novel single-nucleotide substitution, Leu 467 Pro, in the interferon-gamma receptor 1 gene associated with allergic diseases.

  International journal of molecular medicine 20030801

• A new role of Pro-73 of p47phox in the activation of neutrophil NADPH oxidase.

  Archives of biochemistry and biophysics 20030801

• Novel proline hydroxylase activities in the pneumocandin-producing fungus Glarea lozoyensis responsible for the formation of trans 3- and trans 4-hydroxyproline.

  Applied microbiology and biotechnology 20030801

• Proline can have opposite effects on fast and slow protein folding phases.

  Biophysical journal 20030801

• Measurement of 5-hydroxy-2-aminovaleric acid as a specific marker of metal catalysed oxidation of proline and arginine residues of low density lipoprotein apolipoprotein B-100 in human atherosclerotic lesions.

  Journal of clinical pathology 20030801

• L-Serine, D- and L-proline and alanine as respiratory substrates of Helicobacter pylori: correlation between in vitro and in vivo amino acid levels.

  Microbiology (Reading, England) 20030801

• CloN2, a novel acyltransferase involved in the attachment of the pyrrole-2-carboxyl moiety to the deoxysugar of clorobiocin.

  Microbiology (Reading, England) 20030801

• Structural basis of proline-specific exopeptidase activity as observed in human dipeptidyl peptidase-IV.

  Structure (London, England : 1993) 20030801

• The structural roles of conserved Pro196, Pro197 and His199 in the mechanism of thymidylate synthase.

  Protein engineering 20030801

• Influence of external uniaxial cyclic strain on oriented fibroblast-seeded collagen gels.

  Tissue engineering 20030801

• The influence of His94 and Pro149 in modulating the activity of V. cholerae DsbA.

  Antioxidants & redox signaling 20030801

• Repression of formate dehydrogenase in Solanum tuberosum increases steady-state levels of formate and accelerates the accumulation of proline in response to osmotic stress.

  Plant molecular biology 20030801

• Proline- and arginine-rich peptides constitute a novel class of allosteric inhibitors of proteasome activity.

  Biochemistry 20030729

• NMR and CD spectroscopy show that imino acid restriction of the unfolded state leads to efficient folding.

  Biochemistry 20030729

• The swapping of terminal arms in ribonucleases: comparison of the solution structure of monomeric bovine seminal and pancreatic ribonucleases.

  Biochemistry 20030729

• Identification of peptide substrates for human MMP-11 (stromelysin-3) using phage display.

  The Journal of biological chemistry 20030725

• Proline replacements and the simplification of the complex, parallel channel folding mechanism for the alpha subunit of Trp synthase, a TIM barrel protein.

  Journal of molecular biology 20030725

• Characteristics of selenazolidine prodrugs of selenocysteine: toxicity and glutathione peroxidase induction in V79 cells.

  Journal of medicinal chemistry 20030717

• The proline-rich region of mouse p53 influences transactivation and apoptosis but is largely dispensable for these functions.

  Oncogene 20030717

• Carbapenem biosynthesis: confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-proline.

  Journal of the American Chemical Society 20030716

• Mutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1.

  The Biochemical journal 20030715

• Fractalkine (CX3CL1) stimulated by nuclear factor kappaB (NF-kappaB)-dependent inflammatory signals induces aortic smooth muscle cell proliferation through an autocrine pathway.

  The Biochemical journal 20030715

• Potential osmoprotectants for the lactic acid bacteria Pediococcus pentosaceus and Tetragenococcus halophila.

  International journal of food microbiology 20030715

• Formation and stability of the enolates of N-protonated proline methyl ester and proline zwitterion in aqueous solution: a nonenzymatic model for the first step in the racemization of proline catalyzed by proline racemase.

  Biochemistry 20030715

• The structure of the cell cycle protein Cdc14 reveals a proline-directed protein phosphatase.

  The EMBO journal 20030715

• Flexible DNA bending in HU-DNA cocrystal structures.

  The EMBO journal 20030715

• Comparison of the folding processes of distantly related proteins. Importance of hydrophobic content in folding.

  Journal of molecular biology 20030711

• Group II metabotropic glutamate receptors regulate the vulnerability to hypoxic brain damage.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030709

• The two NK-1 binding sites are distinguished by one radiolabelled substance P analogue.

  Biochemical and biophysical research communications 20030704

• Human recombinant endopeptidase PHEX has a strict S1' specificity for acidic residues and cleaves peptides derived from fibroblast growth factor-23 and matrix extracellular phosphoglycoprotein.

  The Biochemical journal 20030701

• Neuropathological features of a case with schizophrenia and prion protein gene P102L mutation before onset of Gerstmann-Sträussler-Scheinker disease.

  Acta neuropathologica 20030701

• Mutational Engineering of the cyanobacterium Nostoc muscorum for resistance to growth-inhibitory action of LiCl and NaCl.

  Current microbiology 20030701

• Effect of dynamic hydrostatic pressure on rabbit intervertebral disc cells.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20030701

• Alteration of protein constituents induced by low-energy (<35 eV) electrons: II. Dissociative electron attachment to amino acids containing cyclic groups.

  Radiation research 20030701

• The p53 codon 72 genotypes in HPV infection and cervical disease.

  European journal of obstetrics, gynecology, and reproductive biology 20030701

• Enhancement of low-voltage-activated calcium currents by group II metabotropic glutamate receptors in rat retinal ganglion cells.

  Molecular and cellular neurosciences 20030701

• Autoinhibition of Bcr-Abl through its SH3 domain.

  Molecular cell 20030701

• [The identification of the immunodominant gliadin epitope].

  Harefuah 20030701

• Fine tuning the myosin motor: the role of the essential light chain in striated muscle myosin.

  Biochimie 20030701

• Effects of selective prostaglandin EP2 and EP4 receptor agonists on bone resorption and formation in fetal rat organ cultures.

  Prostaglandins & other lipid mediators 20030701

• IGF-1 potentiation of IL-4-induced CD23/Fc(epsilon)RII expression in human B cells.

  Molecules and cells 20030630

• Asymmetric synthesis of cis-5-tert-butylproline with metal carbenoid NH insertion.

  The Journal of organic chemistry 20030627

• Protein prosthesis: a nonnatural residue accelerates folding and increases stability.

  Journal of the American Chemical Society 20030625

• Determinants of intra versus intermolecular self-association within the regulatory domains of Rlk and Itk.

  Journal of molecular biology 20030620

• Determination of free proline and monosaccharides in wine samples by high-performance anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD).

  Journal of agricultural and food chemistry 20030618

• A PAR domain transcription factor is involved in the expression from a hematopoietic-specific promoter for the human LMO2 gene.

  Blood 20030615

• Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium.

  Cancer research 20030615

• Dykellic acid inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting nuclear factor kappa B transcriptional activity.

  Cancer research 20030615

• Synthesis of a novel cis-proline-derived cyclic type VI beta-turn mimic via ring-closing metathesis.

  The Journal of organic chemistry 20030613

• A second site rescue mutation partially restores functional expression to the serotonin transporter mutant V382P.

  Biochemistry 20030610

• Formation of odorants in Maillard model systems based on l-proline as affected by pH.

  Journal of agricultural and food chemistry 20030604

• Diesel exhaust particles upregulate eotaxin gene expression in human bronchial epithelial cells via nuclear factor-kappa B-dependent pathway.

  American journal of physiology. Lung cellular and molecular physiology 20030601

• Measurement of protein metabolism in epidermis and dermis.

  American journal of physiology. Endocrinology and metabolism 20030601

• PRQFVamide, a novel pentapeptide identified from the CNS and gut of Aplysia.

  Journal of neurophysiology 20030601

• Structural insights into the catalytic mechanism of cyclophilin A.

  Nature structural biology 20030601

• An electronic effect on protein structure.

  Protein science : a publication of the Protein Society 20030601

• Why is Leu55-->Pro55 transthyretin variant the most amyloidogenic: insights from molecular dynamics simulations of transthyretin monomers.

  Protein science : a publication of the Protein Society 20030601

• Mode of action of neuropeptides from the adipokinetic hormone family.

  General and comparative endocrinology 20030601

• Respiratory insufficiency in desminopathy patients caused by introduction of proline residues in desmin c-terminal alpha-helical segment.

  Muscle & nerve 20030601

• The major envelope protein, GP5, of a European porcine reproductive and respiratory syndrome virus contains a neutralization epitope in its N-terminal ectodomain.

  The Journal of general virology 20030601

• Activation of selective transcription factors and cytokines by water-soluble extract from Lentinus lepideus.

  Experimental biology and medicine (Maywood, N.J.) 20030601

• Monitoring expression profiles of Arabidopsis gene expression during rehydration process after dehydration using ca 7000 full-length cDNA microarray.

  The Plant journal : for cell and molecular biology 20030601

• Rapamycin treatment results in GATA factor-independent hyperphosphorylation of the proline utilization pathway activator in Saccharomyces cerevisiae.

  Eukaryotic cell 20030601

• Frontotemporal dementia and parkinsonism with the P301S tau gene mutation in a Jewish family.

  Journal of neurology 20030601

• Proline can be utilized as an energy substrate during flight of Aedes aegypti females.

  Journal of insect physiology 20030601

• Distinct phospholipase C-gamma-dependent signaling pathways in the Drosophila eye and wing are revealed by a new small wing allele.

  Genetics 20030601

• Effect of proline on creatine kinase activity in rat brain.

  Metabolic brain disease 20030601

• Production of nitric oxide and tumor necrosis factor-alpha by Smilacis rhizoma in mouse peritoneal macrophages.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030601

• Characterisation of the active site of a newly-discovered and potentially significant post-proline cleaving endopeptidase called ZIP using LC-UV-MS.

  The Analyst 20030601

• Leucine 7 to proline 7 polymorphism of the preproneuropeptide Y gene is not associated with restenosis after coronary stenting.

  Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20030601

• Cyclopropyl glycine and proline-containing preparation noopept evoke two types of membrane potential responses in synaptoneurosomes.

  Bulletin of experimental biology and medicine 20030601

• Salt-dependent expression of a nitrate transporter and two amino acid transporter genes in Mesembryanthemum crystallinum.

  Plant molecular biology 20030601

• Changes of plasma membrane ATPase activities and proline accumulation in twigs of Casuarina under different growth conditions.

  Shi yan sheng wu xue bao 20030601

• Electrothermal atomic absorption spectrometric-determination of cobalt in human serum and urine.

  Acta pharmaceutica (Zagreb, Croatia) 20030601

• Synthesis of cyclic proline-containing peptides via ring-closing metathesis.

  Organic letters 20030529

• Different protofilament-dependence of the microtubule binding between MAP2 and MAP4.

  Biochemical and biophysical research communications 20030523

• Antinociception by a peripherally administered novel endomorphin-1 analogue containing beta-proline.

  European journal of pharmacology 20030523

• Proline isomerization in bovine pancreatic ribonuclease A. 2. Folding conditions.

  Biochemistry 20030520

• The direct interaction of phospholipase C-gamma 1 with phospholipase D2 is important for epidermal growth factor signaling.

  The Journal of biological chemistry 20030516

• The design of novel N-4'-pyridinyl-alpha-methyl proline derivatives as potent catalysts for the kinetic resolution of alcohols.

  The Journal of organic chemistry 20030516

• Asymmetric hydrogenations for the synthesis of Boc-protected 4-alkylprolinols and prolines.

  The Journal of organic chemistry 20030516

• The role of an evolutionarily conserved cis-proline in the thioredoxin-like domain of human class Alpha glutathione transferase A1-1.

  The Biochemical journal 20030515

• Organocatalytic asymmetric assembly reactions: one-pot synthesis of functionalized beta-amino alcohols from aldehydes, ketones, and azodicarboxylates.

  Organic letters 20030515

• A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.

  Cancer research 20030515

• Selective detection of copper ions in aqueous solution based on an evanescent wave infrared absorption spectroscopic method.

  Analytical chemistry 20030515

• C-terminal region of herpes simplex virus ICP8 protein needed for intranuclear localization.

  Virology 20030510

• The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein.

  The Journal of biological chemistry 20030509

• Semisynthesis and characterization of the first analogues of pro-neuropeptide y.

  Chembiochem : a European journal of chemical biology 20030509

• Zn-proline catalyzed direct aldol reaction in aqueous media.

  Chemical communications (Cambridge, England) 20030507

• Stability against enzymatic hydrolysis of endomorphin-1 analogues containing beta-proline.

  Organic & biomolecular chemistry 20030507

• Mitotic regulation of ribosomal S6 kinase 1 involves Ser/Thr, Pro phosphorylation of consensus and non-consensus sites by Cdc2.

  The Journal of biological chemistry 20030502

• Interaction between Src and a C-terminal proline-rich motif of Akt is required for Akt activation.

  The Journal of biological chemistry 20030502

• A glutamine to proline exchange at amino acid residue 1098 in sucrase causes a temperature-sensitive arrest of sucrase-isomaltase in the endoplasmic reticulum and cis-Golgi.

  The Journal of biological chemistry 20030502

• Arginine, ornithine, and proline interconversion is dependent on small intestinal metabolism in neonatal pigs.

  American journal of physiology. Endocrinology and metabolism 20030501

• A quantitative structure-activity relationship study of hydroxamate matrix metalloproteinase inhibitors derived from functionalized 4-aminoprolines.

  Bioorganic & medicinal chemistry 20030501

• A novel pyrroline-5-carboxylic acid and acetoacetic acid adduct in hyperprolinaemia type II.

  Clinica chimica acta; international journal of clinical chemistry 20030501

• Protein uptake disturbs collagen homeostasis in proximal tubule-derived cells.

  Kidney international. Supplement 20030501

• Molecular pathways involved in the antineoplastic effects of calcitriol on insulinoma cells.

  Endocrinology 20030501

• Alcohol consumption decreases IL-2-induced NF-kappaB activity in enriched NK cells from C57BL/6 mice.

  Toxicological sciences : an official journal of the Society of Toxicology 20030501

• The transcobalamin codon 259 polymorphism should be designated 776C>G, not 775G>C.

  Blood 20030501

• The peroxisome proliferator-activated receptor-gamma2 gene polymorphism (Pro12Ala) beneficially influences insulin resistance and its tracking from childhood to adulthood: the Bogalusa Heart Study.

  Diabetes 20030501

• Cleavage N-terminal to proline: analysis of a database of peptide tandem mass spectra.

  Analytical chemistry 20030501

• 4'-iodo-4'-deoxydoxorubicin and tetracyclines disrupt transthyretin amyloid fibrils in vitro producing noncytotoxic species: screening for TTR fibril disrupters.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030501

• [Typical features of craniofacial growth of the FGFR3-associated coronal synostosis syndrome (so-called Muenke craniosynostosis)].

  Mund-, Kiefer- und Gesichtschirurgie : MKG 20030501

• Synthetic inhibitors of proline-rich ligand-mediated protein-protein interaction: potent analogs of UCS15A.

  Chemistry & biology 20030501

• Toxicity of free proline revealed in an arabidopsis T-DNA-tagged mutant deficient in proline dehydrogenase.

  Plant & cell physiology 20030501

• Pyrrolidine dithiocarbamate provides protection against hypothermic preservation and transplantation injury in the rat liver: the role of heme oxygenase-1.

  Surgery 20030501

• A crucial role for profilin-actin in the intracellular motility of Listeria monocytogenes.

  EMBO reports 20030501

• Crystallization of the proline-rich-peptide binding domain of human type I collagen prolyl 4-hydroxylase.

  Acta crystallographica. Section D, Biological crystallography 20030501

• Hb St. Luke's [alpha95(G2)Pro --> Arg (alpha1)].

  Hemoglobin 20030501

• Cold-spray ionization mass spectrometry: principle and applications.

  Journal of mass spectrometry : JMS 20030501

• [Surgical therapy of female urinary incontinence].

  Therapeutische Umschau. Revue therapeutique 20030501

• Stranded in isolation: structural role of isolated extended strands in proteins.

  Protein engineering 20030501

• Further evidence for the reliance of catalysis by rabbit muscle pyruvate kinase upon isomerization of the ternary complex between enzyme and products.

  Biophysical chemistry 20030501

• Cyclosporin A prevents the hypoxic adaptation by activating hypoxia-inducible factor-1alpha Pro-564 hydroxylation.

  The Journal of biological chemistry 20030425

• Disulfide pairings and secondary structure of porcine beta-microseminoprotein.

  FEBS letters 20030424

• The structure and function of proline recognition domains.

  Science's STKE : signal transduction knowledge environment 20030422

• Identification of regions of the tomato gamma-glutamyl kinase that are involved in allosteric regulation by proline.

  The Journal of biological chemistry 20030418

• Proline-glutamate chimeras in isopeptides. Synthesis and biological evaluation of conformationally restricted glutathione analogues.

  Bioorganic & medicinal chemistry 20030417

• Origins of opposite absolute stereoselectivities in proline-catalyzed direct Mannich and aldol reactions.

  Organic letters 20030417

• Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII.

  The Biochemical journal 20030415

• Shear stress augments the enhanced adhesive phenotype of cells expressing the Pro33 isoform of integrin beta3.

  FEBS letters 20030410

• Relationship between ligand binding and YIPP motif in the C-terminal region of human AT1 receptor.

  Biochimica et biophysica acta 20030407

• Metal ions induce bone-resorbing cytokine production through the redox pathway in synoviocytes and bone marrow macrophages.

  Biomaterials 20030401

• Dipole interaction model predicted pi-pi* circular dichroism of cyclo(L-Pro)3 using structures created by semi-empirical, ab initio, and molecular mechanics methods.

  The journal of peptide research : official journal of the American Peptide Society 20030401

• Proline induces oxidative stress in cerebral cortex of rats.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20030401

• Structure and dynamics of the DNA-binding protein HU of B. stearothermophilus investigated by Raman and ultraviolet-resonance Raman spectroscopy.

  Protein science : a publication of the Protein Society 20030401

• Solid-state NMR investigation of the buried X-proline peptide bonds of bacteriorhodopsin.

  Biochemistry 20030401

• Kinetic mechanisms of glycine oxidase from Bacillus subtilis.

  European journal of biochemistry 20030401

• Modulation of IkappaB kinase autophosphorylation and activity following brain ischemia.

  Acta pharmacologica Sinica 20030401

• Effect of the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor (PPAR) gamma2 gene on the expression of PPARgamma target genes in adipose tissue of massively obese subjects.

  The Journal of clinical endocrinology and metabolism 20030401

• Effect of amino acids on cryopreservation of cynomolgus monkey (Macaca fascicularis) sperm.

  American journal of primatology 20030401

• A new case of resistance to thyroid hormone caused by a de novo P453T mutation in the thyroid hormone receptor gene in an Israeli child.

  Thyroid : official journal of the American Thyroid Association 20030401

• Enhanced endothelium-dependent vasodilation in subjects with Proline7 substitution in the signal peptide of neuropeptide Y.

  Atherosclerosis 20030401

• Effect of glyprolines on norepinephrine tone of isolated rat aortic rings.

  Bulletin of experimental biology and medicine 20030401

• Determination of the post-translational modifications of salivary acidic proline-rich proteins.

  European journal of morphology 20030401

• The overlapping RNA-binding domains of p33 and p92 replicase proteins are essential for tombusvirus replication.

  Virology 20030330

• Identification of a proline-rich Akt substrate as a 14-3-3 binding partner.

  The Journal of biological chemistry 20030321

• Amino-zinc-enolate carbometalation reactions: application to ring closure of terminally substituted olefin for the asymmetric synthesis of cis- and trans-3-prolinoleucine.

  The Journal of organic chemistry 20030321

• Serine-cis-proline and serine-trans-proline isosteres: stereoselective synthesis of (Z)- and (E)-alkene mimics by Still-Wittig and Ireland-Claisen rearrangements.

  The Journal of organic chemistry 20030321

• Proline-rich tyrosine kinase 2 and Rac activation by chemokine and integrin receptors controls NK cell transendothelial migration.

  Journal of immunology (Baltimore, Md. : 1950) 20030315

• HIF hydroxylation and the mammalian oxygen-sensing pathway.

  The Journal of clinical investigation 20030315

• [Low prevalence of the Leu7/Pro polymorphism in the signal peptide of preproneuropeptide Y in the Spanish Mediterranean population].

  Medicina clinica 20030315

• Crystal structure of triosephosphate isomerase complexed with 2-phosphoglycolate at 0.83-A resolution.

  The Journal of biological chemistry 20030314

• Inhibitory specificity change of the ovomucoid third domain of the silver pheasant upon introduction of an engineered Cys14-Cys39 bond.

  Biochemistry 20030311

• Peptidyl aldehyde inhibitors of calpain incorporating P2-proline mimetics.

  Bioorganic & medicinal chemistry letters 20030310

• Reverse turn induced pi-facial selectivity during polyaniline-supported cobalt(II) salen catalyzed aerobic epoxidation of N-cinnamoyl L-proline derived peptides.

  The Journal of organic chemistry 20030307

• Development and conformational analysis of a pseudoproline-containing turn mimic.

  The Journal of organic chemistry 20030307

• Quantum mechanical predictions of the stereoselectivities of proline-catalyzed asymmetric intermolecular aldol reactions.

  Journal of the American Chemical Society 20030305

• Proline-catalyzed asymmetric alpha-amination of aldehydes and ketones--an astonishingly simple access to optically active alpha-hydrazino carbonyl compounds.

  Angewandte Chemie (International ed. in English) 20030303

• A convenient incorporation of conformationally constrained 5,5-dimethylproline into the ribonuclease A 89-124 sequence by condensation of synthetic peptide fragments.

  The journal of peptide research : official journal of the American Peptide Society 20030301

• The codon 72 polymorphic variants of p53 have markedly different apoptotic potential.

  Nature genetics 20030301

• Structure of a gametocyte protein essential for sexual development in Plasmodium falciparum.

  Nature structural biology 20030301

• Biosynthetic response of passaged chondrocytes in a type II collagen scaffold to mechanical compression.

  Journal of biomedical materials research. Part A 20030301

• The effect of the polyproline II (PPII) conformation on the denatured state entropy.

  Protein science : a publication of the Protein Society 20030301

• Proline reduces acetylcholinesterase activity in cerebral cortex of rats.

  Metabolic brain disease 20030301

• Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation.

  European journal of biochemistry 20030301

• Identification and characterization of amphiphysin II as a novel cellular interaction partner of the hepatitis C virus NS5A protein.

  The Journal of general virology 20030301

• Analysis of the relationship between the Pro12Ala variant in the PPAR-gamma2 gene and the response rate to therapy with pioglitazone in patients with type 2 diabetes.

  Diabetes care 20030301

• Specific induction and carbon/nitrogen repression of arginine catabolism gene of Aspergillus nidulans--functional in vivo analysis of the otaA promoter.

  Fungal genetics and biology : FG & B 20030301

• PET imaging of pulmonary fibrosis.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030301

• Antioxidant amplifies antibiotic protection in the cecal ligation and puncture model of microbial sepsis through interleukin-10 production.

  Shock (Augusta, Ga.) 20030301

• Selective stimulation of collagen synthesis in the presence of costimulatory insulin signaling by connective tissue growth factor in scleroderma fibroblasts.

  Arthritis and rheumatism 20030301

• Method enabling firefly luciferase-based bioluminometric assays at elevated temperatures.

  Analytical biochemistry 20030301

• Conformation of a group 2 late embryogenesis abundant protein from soybean. Evidence of poly (L-proline)-type II structure.

  Plant physiology 20030301

• Assignments of 1H, 15N and 13C resonances of the proline-rich matrix protein of Moloney murine leukemia virus (MA MoMuLV).

  Journal of biomolecular NMR 20030301

• Cellular defense against singlet oxygen-induced oxidative damage by cytosolic NADP+-dependent isocitrate dehydrogenase.

  Free radical research 20030301

• Chemical composition of chicken eggshell and shell membranes.

  Poultry science 20030301

• Breast and lung cancer are associated with a decrease in blood cell amino acid content.

  The Journal of nutritional biochemistry 20030301

• Full-length rat amylin forms fibrils following substitution of single residues from human amylin.

  Journal of molecular biology 20030227

• Novel alpha-melanocyte stimulating hormone peptide analogues with high candidacidal activity.

  Journal of medicinal chemistry 20030227

• Nickel in subunit beta of the acetyl-CoA decarbonylase/synthase multienzyme complex in methanogens. Catalytic properties and evidence for a binuclear Ni-Ni site.

  The Journal of biological chemistry 20030221

• The proline-rich domain of dynamin-2 is responsible for dynamin-dependent in vitro potentiation of endothelial nitric-oxide synthase activity via selective effects on reductase domain function.

  The Journal of biological chemistry 20030221

• Asymmetric intermolecular C-H activation, using immobilized dirhodium tetrakis((S)-N-(dodecylbenzenesulfonyl)- prolinate) as a recoverable catalyst.

  Organic letters 20030220

• Effects of engineering uphill electron transfer into the methylamine dehydrogenase-amicyanin-cytochrome c-551i complex.

  Biochemistry 20030218

• Conformers of gaseous proline.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030217

• Structure validation by Calpha geometry: phi,psi and Cbeta deviation.

  Proteins 20030215

• No association between the TGF-beta 1 Leu10Pro polymorphism and osteoporosis among white women in the United States.

  The American journal of medicine 20030215

• Interaction of trigger factor with the ribosome.

  Journal of molecular biology 20030214

• Enhanced activation of mitogen-activated protein kinase and myosin light chain kinase by the Pro33 polymorphism of integrin beta 3.

  The Journal of biological chemistry 20030207

• Kinetic mechanism and catalysis of a native-state prolyl isomerization reaction.

  Journal of molecular biology 20030207

• Probing the stereoselectivity of the Heck arylation of endocyclic enecarbamates with diazonium salts. Concise syntheses of (2S,5R)-phenylproline methyl ester and Schramm's C-azanucleoside.

  Organic letters 20030206

• Impact of azaproline on amide cis-trans isomerism: conformational analyses and NMR studies of model peptides including TRH analogues.

  Journal of the American Chemical Society 20030205

• Scrapie-like prion protein accumulates in aggresomes of cyclosporin A-treated cells.

  The EMBO journal 20030203

• The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth.

  The EMBO journal 20030203

• Proline-directed phosphorylation and isomerization in mitotic regulation and in Alzheimer's Disease.

  BioEssays : news and reviews in molecular, cellular and developmental biology 20030201

• Acrokeratosis verruciformis of Hopf is caused by mutation in ATP2A2: evidence that it is allelic to Darier's disease.

  The Journal of investigative dermatology 20030201

• The proline-rich region of the ecotropic Moloney murine leukaemia virus envelope protein tolerates the insertion of the green fluorescent protein and allows the generation of replication-competent virus.

  The Journal of general virology 20030201

• Impairment of signal transduction in response to stimulation of the naturally occurring Pro279Leu variant of the h5-HT7(a) receptor.

  Pharmacogenetics 20030201

• Autosomal dominant external ophthalmoplegia and bipolar affective disorder associated with a mutation in the ANT1 gene.

  Neuromuscular disorders : NMD 20030201

• RU486-induced growth inhibition of human endometrial cells involves the nuclear factor-kappa B signaling pathway.

  The Journal of clinical endocrinology and metabolism 20030201

• Three hydrates of the bisphosphonate risedronate, consisting of one molecular and two ionic structures.

  Acta crystallographica. Section C, Crystal structure communications 20030201

• Photometric determination of proline in quartz microplates: remarks on specificity.

  Analytical biochemistry 20030201

• Association of the PRO12ALA polymorphism of the PPAR-gamma2 gene with oxidized low-density lipoprotein and cardiolipin autoantibodies in nondiabetic and type 2 diabetic subjects.

  Metabolism: clinical and experimental 20030201

• Light-dependent induction of proline biosynthesis by abscisic acid and salt stress is inhibited by brassinosteroid in Arabidopsis.

  Plant molecular biology 20030201

• Gene expression of Sh3d19, a novel adaptor protein with five Src homology 3 domains, in anagen mouse hair follicles.

  Journal of dermatological science 20030201

• Structural basis for specific binding of the Gads SH3 domain to an RxxK motif-containing SLP-76 peptide: a novel mode of peptide recognition.

  Molecular cell 20030201

• Proline accumulation and glutamine synthetase activity are increased by salt-induced proteolysis in cashew leaves.

  Journal of plant physiology 20030201

• Response of barley seedlings to UV-B radiation as affected by NaCl.

  Journal of plant physiology 20030201

• Physiological mechanism of plant roots exposed to cadmium.

  Chemosphere 20030201

• Cyclooxygenase-2 inhibitor NS-398 suppresses cell growth and constitutive production of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer cells.

  Cancer science 20030201

• The role of hemolymph proline as a nitrogen sink during blood meal digestion by the mosquito Aedes aegypti.

  Journal of insect physiology 20030201

• Co-administration of proline and inorganic iron enhance the improvement of behavioral and hematological function of iron-deficient anemic rats.

  Journal of nutritional science and vitaminology 20030201

• Isolation by zinc-affinity chromatography of the histidine-proline-rich-glycoprotein molecule associated with rabbit skeletal muscle AMP deaminase. Evidence that the formation of a protein-protein complex between the catalytic subunit and the novel component is critical for the stability of the enzyme.

  Biochimica et biophysica acta 20030131

• A new turn structure for the formation of beta-hairpins in peptides.

  Journal of the American Chemical Society 20030129

• Fibrinogen Magdeburg I: a novel variant of human fibrinogen with an amino acid exchange in the fibrinopeptide A (Aalpha 9, Leu-->Pro).

  Thrombosis research 20030125

• High resolution crystal structures of human Rab5a and five mutants with substitutions in the catalytically important phosphate-binding loop.

  The Journal of biological chemistry 20030124

• The focal adhesion and nuclear targeting capacity of the LIM-containing lipoma-preferred partner (LPP) protein.

  The Journal of biological chemistry 20030124

• Palladium(II) complex as a sequence-specific peptidase: hydrolytic cleavage under mild conditions of X-Pro peptide bonds in X-Pro-Met and X-Pro-His segments.

  Journal of the American Chemical Society 20030122

• Scanning mutagenesis of the alpha repeats and of the transmembrane acidic residues of the human retinal cone Na/Ca-K exchanger.

  Biochemistry 20030121

• Identification of TNF-alpha inhibitors from a split-pool library based on a tyrosine-proline peptidomimetic scaffold.

  Bioorganic & medicinal chemistry letters 20030120

• Biosynthesis of 4-methylproline in cyanobacteria: cloning of nosE and nosF genes and biochemical characterization of the encoded dehydrogenase and reductase activities.

  The Journal of organic chemistry 20030110

• Kinetic and stereochemical evidence for the involvement of only one proline molecule in the transition states of proline-catalyzed intra- and intermolecular aldol reactions.

  Journal of the American Chemical Society 20030108

• Tandem ligation of multipartite peptides with cell-permeable activity.

  Journal of the American Chemical Society 20030108

• Co-translational incorporation of trans-4-hydroxyproline into recombinant proteins in bacteria.

  The Journal of biological chemistry 20030103

• Solution structure of a circular-permuted variant of the potent HIV-inactivating protein cyanovirin-N: structural basis for protein stability and oligosaccharide interaction.

  Journal of molecular biology 20030103

• Characterization of a novel human breast cancer associated gene (BCA3) encoding an alternatively spliced proline-rich protein.

  Biochimica et biophysica acta 20030103

• Redox-regulated mechanisms of IL-4-induced MCP-1 expression in human vascular endothelial cells.

  American journal of physiology. Heart and circulatory physiology 20030101

• Glucocorticoids aggravate hyperoxia-induced lung injury through decreased nuclear factor-kappa B activity.

  American journal of physiology. Lung cellular and molecular physiology 20030101

• Dermal fibroblasts respond to mechanical conditioning in a strain profile dependent manner.

  Biorheology 20030101

• Backbone dynamics and hydrogen exchange of Pseudomonas aeruginosa ferricytochrome c(551).

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20030101

• Remote chirality transfer in nucleophilic catalysis with N-(4-pyridinyl)-L-proline derivatives.

  Chirality 20030101

• Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D.

  Drug metabolism and disposition: the biological fate of chemicals 20030101

• N-terminal protein sequencing for special applications.

  Methods in molecular biology (Clifton, N.J.) 20030101

• Regulation of estrogen receptors and MMP-2 expression by estrogens in human retinal pigment epithelium.

  Investigative ophthalmology & visual science 20030101

• Dichlorobis(DL-proline-kappaO)zinc(II).

  Acta crystallographica. Section C, Crystal structure communications 20030101

• A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.

  The Journal of clinical investigation 20030101

• A third MRX family (MRX68) is the result of mutation in the long chain fatty acid-CoA ligase 4 (FACL4) gene: proposal of a rapid enzymatic assay for screening mentally retarded patients.

  Journal of medical genetics 20030101

• The severe form of type I hyperprolinaemia results from homozygous inactivation of the PRODH gene.

  Journal of medical genetics 20030101

• Isolation and characterization of the mouse ubiquitin-specific protease Usp15.

  Mammalian genome : official journal of the International Mammalian Genome Society 20030101

• Extensive hepatic uptake of Pz-peptide, a hydrophilic proline-containing pentapeptide, into isolated hepatocytes compared with colonocytes and Caco-2 cells.

  Archives of pharmacal research 20030101

• Salt-tolerant mutants in glycophytic salinity response (GSR) genes in Catharanthus roseus.

  TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20030101

• TGF-beta stimulates collagen (I) in vascular smooth muscle cells via a short element in the proximal collagen promoter.

  The Journal of surgical research 20030101

• Scorpion toxins from Buthus martensii Karsch all possess a predicted alpha-tight-turn.

  Cell biochemistry and biophysics 20030101

• [Proline-specific endopeptidases].

  Bioorganicheskaia khimiia 20030101

• Effects of static electromagnetic fields on characteristics of MG-63 osteoblasts grown in culture.

  Biomedical sciences instrumentation 20030101

• Phenotypic expression of the C282Y/Q283P compound heterozygosity in HFE and molecular modeling of the Q283P mutation effect.

  Blood cells, molecules & diseases 20030101

• Rapid parallel synthesis of dipeptide diphenyl phosphonate esters as inhibitors of dipeptidyl peptidases.

  Journal of combinatorial chemistry 20030101

• Cultures of ligament fibroblasts in fibrin matrix gel.

  Connective tissue research 20030101

• [Free and bound amino acids during germination of maize seeds with implemented foreign prolamines].

  Prikladnaia biokhimiia i mikrobiologiia 20030101

• [Experimental study on effects of endothelin in the proliferation and collagen synthesis of human scar-derived fibroblasts].

  Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery 20030101

• Studies on the mechanism of the osmoresistance of spores of Bacillus subtilis.

  Journal of applied microbiology 20030101

• TNF alpha down-regulates CD105 expression in vascular endothelial cells: a comparative study with TGF beta 1.

  Anticancer research 20030101

• Studies on type I collagen in skin fibroblasts cultured from twins with lethal osteogenesis imperfecta.

  Acta biochimica Polonica 20030101

• Proton affinity of proline and modified prolines using the kinetic method: role of the conformation investigated by ab initio calculations.

  Rapid communications in mass spectrometry : RCM 20030101

• [New regulatory peptides in rat stomach secretion (amylin, PGP, semax)].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20030101

• Design and synthesis of fluorescent beta-cyclodextrins for the enantioselective sensing of alpha-amino acids.

  Chirality 20030101

• Gas-phase basicity of glycine, alanine, proline, serine, lysine, histidine and some of their peptides by the thermokinetic method.

  European journal of mass spectrometry (Chichester, England) 20030101

• Amelogenin self-assembly and the role of the proline located within the carboxyl-teleopeptide.

  Connective tissue research 20030101

• Phenotypic expression of the C282Y/Q283P compound heterozygosity in HFE and molecular modeling of the Q283P mutation effect.

  Blood cells, molecules & diseases 20030101

• Getting in the ring: proline-directed substrate specificity in the cell cycle proteins Cdc14 and CDK2-cyclinA3.

  Cell cycle (Georgetown, Tex.) 20030101

• Cytokine action and oxidative stress response in differentiated neuroblastoma SH-SY5Y cells.

  Acta biochimica Polonica 20030101

• A common polymorphism in the oxygen-dependent degradation (ODD) domain of hypoxia inducible factor-1alpha (HIF-1alpha) does not impair Pro-564 hydroxylation.

  Molecular cancer 20030101

• Pro-inflammatory cytokine-induced matrix metalloproteinase-1 (MMP-1) secretion in human pancreatic periacinar myofibroblasts.

  Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20030101

• Effect of glutamine dipeptide on hepatic regeneration in partially hepatectomized malnourished rats.

  Nutrition (Burbank, Los Angeles County, Calif.) 20030101

• [Localization of proline-rich peptide (galarmin) in brain structures of rats (immunohistochemical study)].

  Morfologiia (Saint Petersburg, Russia) 20030101

• Association of p53 codon Arg72Pro and p73 G4C14-to-A4T14 at exon 2 genetic polymorphisms with the risk of Japanese breast cancer.

  Breast cancer (Tokyo, Japan) 20030101

• The structure of tri-proline in water probed by polarized Raman, Fourier transform infrared, vibrational circular dichroism, and electric ultraviolet circular dichroism spectroscopy.

  Biopolymers 20030101

• [Semax and some glyproline peptides accelerate the healing of acetic ulcers in rats].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20030101

• Mechanical conditioning influences the metabolic response of cell-seeded constructs.

  Cells, tissues, organs 20030101

• Modulation of the activation of extracellular signal-regulated kinase (ERK) and the production of inflammatory mediators by ADP-ribosylation inhibitors.

  Biological chemistry 20030101

• Tissue damage precludes the use of the everted sleeve technique to measure nutrient uptake in a small migratory shorebird, the western sandpiper (Calidris mauri).

  Physiological and biochemical zoology : PBZ 20030101

• Kinetics of gas-phase hydrogen/deuterium exchange and gas-phase structure of protonated phenylalanine, proline, tyrosine and tryptophan.

  Rapid communications in mass spectrometry : RCM 20030101

• Effects of glycine and proline on the calcium activation properties of skinned muscle fibre segments from crayfish and rat.

  Journal of muscle research and cell motility 20030101

• [Highly stable regulatory oligopeptides: experience and applications].

  Patologicheskaia fiziologiia i eksperimental'naia terapiia 20030101

• Beckwith-Wiedemann syndrome-associated hepatoblastoma: wnt signal activation occurs later in tumorigenesis in patients with 11p15.5 uniparental disomy.

  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 20030101

• Intervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathy.

  Nephron. Physiology 20030101

• Enhancing stereochemical diversity by means of microwave irradiation in the absence of solvent: synthesis of highly substituted nitroproline esters via 1,3-dipolar reactions.

  Molecular diversity 20030101

• Photoreceptor degeneration in Pro23His and S334ter transgenic rats.

  Advances in experimental medicine and biology 20030101

• Plastocyanin-cytochrome f interactions: the influence of hydrophobic patch mutations studied by NMR spectroscopy.

  Biochemistry 20021231

• Molecular characterization of NikD, a new flavoenzyme important in the biosynthesis of nikkomycin antibiotics.

  Biochemistry 20021231

• Analysis of enantiomers of chiral phenethylamine drugs by capillary gas chromatography/mass spectrometry/flame-ionization detection and pre-column chiral derivatization.

  Journal of biochemical and biophysical methods 20021231

• Investigations of cyclophilin interactions with oligopeptides containing proline by affinity capillary electrophoresis.

  Journal of chromatography. A 20021227

• Conserved proline residue at position 189 in cone visual pigments as a determinant of molecular properties different from rhodopsins.

  Biochemistry 20021224

• Congenital myasthenic syndrome caused by low-expressor fast-channel AChR delta subunit mutation.

  Neurology 20021224

• Follicle-stimulating hormone interacts with exoloop 3 of the receptor.

  The Journal of biological chemistry 20021220

• Requirement of a vasodilator-stimulated phosphoprotein family member for cell adhesion, the formation of filopodia, and chemotaxis in dictyostelium.

  The Journal of biological chemistry 20021220

• Role of dynamic interactions in effective signal transfer for Gbeta stimulation of phospholipase C-beta 2.

  The Journal of biological chemistry 20021220

• Proline cis-trans isomerization and protein folding.

  Biochemistry 20021217

• Synthetic studies of cis-4-Amino-L-proline derivatives as novel lipid lowering agents.

  Bioorganic & medicinal chemistry letters 20021216

• The structure of neutral proline.

  Angewandte Chemie (International ed. in English) 20021216

• A novel variant of the immunoglobulin fold in surface adhesins of Staphylococcus aureus: crystal structure of the fibrinogen-binding MSCRAMM, clumping factor A.

  The EMBO journal 20021216

• Proline homozygosity in codon 72 of p53: a risk genotype for human papillomavirus related cervical cancer in Indian women.

  Cancer letters 20021215

• Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis.

  Circulation research 20021213

• Brain natriuretic Peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases.

  Circulation research 20021213

• One-pot asymmetric synthesis of beta-cyanohydroxymethyl alpha-amino acid derivatives: formation of three contiguous stereogenic centers.

  Organic letters 20021212

• The Trp cage: folding kinetics and unfolded state topology via molecular dynamics simulations.

  Journal of the American Chemical Society 20021211

• Characterization of a novel mammalian Groucho isoform and its role in transcriptional regulation.

  The Journal of biological chemistry 20021206

• Two nonconsensus sites in the Epstein-Barr virus oncoprotein EBNA3A cooperate to bind the co-repressor carboxyl-terminal-binding protein (CtBP).

  The Journal of biological chemistry 20021206

• Molecular dynamics simulations on discoidal HDL particles suggest a mechanism for rotation in the apo A-I belt model.

  Journal of molecular biology 20021206

• Solution structure and ligand recognition of the WW domain pair of the yeast splicing factor Prp40.

  Journal of molecular biology 20021206

• Calcium-dependent homoassociation of E-cadherin by NMR spectroscopy: changes in mobility, conformation and mapping of contact regions.

  Journal of molecular biology 20021206

• H-NS oligomerization domain structure reveals the mechanism for high order self-association of the intact protein.

  Journal of molecular biology 20021206

• Chemistry. The simplest 'enzyme'.

  Science (New York, N.Y.) 20021206

• Glucosylisomaltol, a new indicator of browning reaction in baby cereals and bread.

  Journal of agricultural and food chemistry 20021204

• Translocating proline-rich peptides from the antimicrobial peptide bactenecin 7.

  Biochemistry 20021203

• Folding and assembly of lambda Cro repressor dimers are kinetically limited by proline isomerization.

  Biochemistry 20021203

• Halide-stabilizing residues of haloalkane dehalogenases studied by quantum mechanic calculations and site-directed mutagenesis.

  Biochemistry 20021203

• Topological analysis of peripherin/rds and abnormal glycosylation of the pathogenic Pro216-->Leu mutation.

  The Biochemical journal 20021201

• Chromaproline and Chromaperidine, nicotine agonists, and Donepezil, cholinesterase inhibitor, enhance performance of memory tasks in ovariectomized rats.

  Pharmacology, biochemistry, and behavior 20021201

• Activation of group II mGlu receptors inhibits voltage-gated Ca2+ currents in myenteric neurons.

  American journal of physiology. Gastrointestinal and liver physiology 20021201

• Interleukin 4 co-stimulates the PDGF-BB- and bFGF-mediated proliferation of mesangial cells and myofibroblasts.

  Nephron 20021201

• Structural characterization of a proline-driven conformational switch within the Itk SH2 domain.

  Nature structural biology 20021201

• All-trans retinoic acid improves structure and function of diabetic rat skin in organ culture.

  Diabetes 20021201

• The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish population.

  American journal of human genetics 20021201

• The transcobalamin codon 259 polymorphism influences the risk of human spontaneous abortion.

  Human reproduction (Oxford, England) 20021201

• Activation time course of activator protein-1 and effect of proline dithiocarbamate during ischemia-reperfusion in rat skeletal muscle.

  Annals of plastic surgery 20021201

• Silicon deprivation decreases collagen formation in wounds and bone, and ornithine transaminase enzyme activity in liver.

  Biological trace element research 20021201

• Activation of the cannabinoid CB1 receptor may involve a W6 48/F3 36 rotamer toggle switch.

  The journal of peptide research : official journal of the American Peptide Society 20021201

• Dopamine efflux via wild-type and mutant dopamine transporters: alanine substitution for proline-572 enhances efflux and reduces dependence on extracellular dopamine, sodium and chloride concentrations.

  Brain research. Molecular brain research 20021201

• Effects of proline analog binding on the spectroscopic and redox properties of PutA.

  Archives of biochemistry and biophysics 20021201

• Conserved proline residues near the N-terminus are important for enzymatic activity of class A bacterial acid phosphatases.

  Archives of biochemistry and biophysics 20021201

• Tomato tos1 mutation identifies a gene essential for osmotic tolerance and abscisic acid sensitivity.

  The Plant journal : for cell and molecular biology 20021201

• A proline-threonine substitution in codon 351 of ADH1C is common in Native Americans.

  Alcoholism, clinical and experimental research 20021201

• Early and persistent sensory-psychiatric symptoms in an inherited prion disease with a PrP P105L mutation.

  Journal of neurology 20021201

• Novel mutant human fibronectin FIII9-10 domain pair with increased conformational stability and biological activity.

  Protein engineering 20021201

• A pharmacological analysis of the contractile effects of glutamate on rat and human isolated gut smooth muscle strips.

  Methods and findings in experimental and clinical pharmacology 20021201

• [Cloning and sequencing of the proBA gene from the selected mutant resistant to proline analogue from Bacillus subtilis].

  Yi chuan xue bao = Acta genetica Sinica 20021201

• Role of proline, cysteine and a disulphide bridge in the structure and activity of the anti-microbial peptide gaegurin 5.

  The Biochemical journal 20021115

• Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules.

  The EMBO journal 20021115

• Dissection of c-MOS degron.

  The EMBO journal 20021115

• Syndapins integrate N-WASP in receptor-mediated endocytosis.

  The EMBO journal 20021115

• Catalytic asymmetric 1,3-dipolar cycloaddition reactions of azomethine ylides-a simple approach to optically active highly functionalized proline derivatives.

  Angewandte Chemie (International ed. in English) 20021115

• Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich Syndrome.

  Cell 20021115

• Catalytic diastereoselective Pauson-Khand reaction: an efficient route to enantiopure cyclopenta[c]proline derivatives.

  Organic letters 20021114

• Proline-induced distortions of transmembrane helices.

  Journal of molecular biology 20021108

• Absence of a conserved proline and presence of a conserved tyrosine in the CB2 cannabinoid receptor are crucial for its function.

  FEBS letters 20021106

• Constitutively active NFkappa B is required for the survival of S-type neuroblastoma.

  The Journal of biological chemistry 20021101

• Homozygous proline at codon 72 of p53 as a potential risk factor favoring the development of undifferentiated thyroid carcinoma.

  International journal of oncology 20021101

• The proline-rich, extensin-like receptor kinase-1 (PERK1) gene is rapidly induced by wounding.

  Plant molecular biology 20021101

• Practical enantioselective synthesis of endothelin antagonist S-1255 by dynamic resolution of 4-methoxychromene-3-carboxylic acid intermediate.

  The Journal of organic chemistry 20021101

• Stereoselective synthesis of beta-substituted phenylalanine-beta-phenylisoserine-derived tripeptides using N-cinnamoyl-L-proline as template: synthesis of structural analogues of HIV protease inhibitors.

  The Journal of organic chemistry 20021101

• PPAR(gamma)2 gene Pro12Ala polymorphism may influence serum level of an adipocyte-derived protein, adiponectin, in the Japanese population.

  Metabolism: clinical and experimental 20021101

• Dose-dependent impairment of collagen deposition by topical granulocyte-macrophage colony-stimulating factor in human experimental wounds.

  Annals of surgery 20021101

• Evidence for early cytotoxic aggregates in transgenic mice for human transthyretin Leu55Pro.

  The American journal of pathology 20021101

• Molecular mechanisms of proline-mediated tolerance to toxic heavy metals in transgenic microalgae.

  The Plant cell 20021101

• Capillary electrophoresis with solid-state electrochemiluminescence detector.

  Electrophoresis 20021101

• [Innovative molecular transformation using optically active alpha-amino acids].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20021101

• Development-associated differences in integrative cartilage repair: roles of biosynthesis and matrix.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20021101

• Hb Manawatu [alpha 37(C2)Pro-->Leu]: a new mildly unstable mutation at an invariant proline residue.

  Hemoglobin 20021101

• Hb Rampa [alpha 95(G2)pro-->Ser (alpha 2)] in a family of European ancestry: DNA analysis confirms the CCG-->TCG mutation at codon 95 of the alpha 2-globin gene; clinical and laboratory features.

  Hemoglobin 20021101

• A molecular oyster: a neutral anion receptor containing two cyclopeptide subunits with a remarkable sulfate affinity in aqueous solution.

  Journal of the American Chemical Society 20021030

• Vibrational spectroscopy favors a unique QB binding site at the proximal position in wild-type reaction centers and in the Pro-L209 --> Tyr mutant from Rhodobacter sphaeroides.

  Biochemistry 20021029

• Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch.

  The Journal of biological chemistry 20021025

• Association of p53 codon 72 polymorphism with advanced lung cancer: the Arg allele is preferentially retained in tumours arising in Arg/Pro germline heterozygotes.

  British journal of cancer 20021021

• Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.

  The Journal of biological chemistry 20021018

• Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha.

  The Journal of biological chemistry 20021018

• Proline-rich cell surface antigens of horseshoe crab hemocytes are substrates for protein cross-linking with a clotting protein coagulin.

  The Journal of biological chemistry 20021018

• Parallel channels and rate-limiting steps in complex protein folding reactions: prolyl isomerization and the alpha subunit of Trp synthase, a TIM barrel protein.

  Journal of molecular biology 20021018

• Anodic modification of proline derivatives using a lithium perchlorate/nitromethane electrolyte solution.

  Organic letters 20021017

• Cutting edge: a natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor.

  Journal of immunology (Baltimore, Md. : 1950) 20021015

• The final N-terminal trimming of a subaminoterminal proline-containing HLA class I-restricted antigenic peptide in the cytosol is mediated by two peptidases.

  Journal of immunology (Baltimore, Md. : 1950) 20021015

• The epidermal growth factor receptor juxtamembrane domain has multiple basolateral plasma membrane localization determinants, including a dominant signal with a polyproline core.

  The Journal of biological chemistry 20021011

• Structural model of the transmembrane Fo rotary sector of H+-transporting ATP synthase derived by solution NMR and intersubunit cross-linking in situ.

  Biochimica et biophysica acta 20021011

• Practical synthesis of Boc-protected cis-4-trifluoromethyl and cis-4-difluoromethyl-L- prolines.

  The Journal of organic chemistry 20021004

• The sodium/substrate symporter family: structural and functional features.

  FEBS letters 20021002

• TGF-beta and CTGF have overlapping and distinct fibrogenic effects on human renal cells.

  American journal of physiology. Renal physiology 20021001

• Effect of guanidino modification and proline substitution on the in vitro stability and blood-brain barrier permeability of endomorphin II.

  Journal of pharmaceutical sciences 20021001

• Probing Src homology 2 domain ligand interactions by differential line broadening.

  Biochemistry 20021001

• Assessment of enamelysin (MMP-20) selectivity to three peptide bonds on amelogenin sequence.

  Journal of dental research 20021001

• Can the nitrogenous composition of xylem sap be used to assess salinity stress in Casuarina glauca?

  Tree physiology 20021001

• Heterozygous P250L mutation of fibroblast growth factor receptor 3 in a case of isolated craniosynostosis.

  Journal of medical genetics 20021001

• Tomato plants ectopically expressing Arabidopsis CBF1 show enhanced resistance to water deficit stress.

  Plant physiology 20021001

• ACTCAT, a novel cis-acting element for proline- and hypoosmolarity-responsive expression of the ProDH gene encoding proline dehydrogenase in Arabidopsis.

  Plant physiology 20021001

• Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.

  Journal of leukocyte biology 20021001

• Suppression of cerulein-induced cytokine expression by antioxidants in pancreatic acinar cells.

  Laboratory investigation; a journal of technical methods and pathology 20021001

• Amino acid content of cell cultures infected with Cowdria ruminantium propagated in a protein-free medium.

  Annals of the New York Academy of Sciences 20021001

• Competitive formation of 10- and 7-membered hydrogen-bonded rings of proline-containing model peptides.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20021001

• FindPept, a tool to identify unmatched masses in peptide mass fingerprinting protein identification.

  Proteomics 20021001

• A software tool for the prediction of Xaa-Pro peptide bond conformations in proteins based on 13C chemical shift statistics.

  Journal of biomolecular NMR 20021001

• Individual and combined effect of mercury and manganese on phenol and proline content in leaf and stem of mungbean seedlings.

  Journal of environmental biology 20021001

• Modular arrangement and secretion of a multidomain serine protease. Evidence for involvement of proline-rich region and N-glycans in the secretion pathway.

  The Journal of biological chemistry 20020927

• In vivo and in vitro phosphorylation at Ser-493 in the glutamate (E)-segment of neurofilament-H subunit by glycogen synthase kinase 3beta.

  The Journal of biological chemistry 20020927

• Chondrocyte protein with a poly-proline region is a novel protein expressed by chondrocytes in vitro and in vivo.

  Biochimica et biophysica acta 20020927

• Dicarboxylic acid bis(L-prolyl-pyrrolidine) amides as prolyl oligopeptidase inhibitors.

  Journal of medicinal chemistry 20020926

• Cellular munc18c levels can modulate glucose transport rate and GLUT4 translocation in 3T3L1 cells.

  FEBS letters 20020925

• Synthesis and 12-helical secondary structure of beta-peptides containing (2R,3R)-aminoproline.

  Organic letters 20020919

• PRODH mutations and hyperprolinemia in a subset of schizophrenic patients.

  Human molecular genetics 20020915

• Protein dynamics: imidazole and 2-mercaptoethanol binding to the Rhodobacter capsulatus cytochrome c(2) mutant, glycine 95 proline.

  Archives of biochemistry and biophysics 20020915

• Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets.

  The Journal of clinical investigation 20020915

• Proline residues at the C terminus of nascent chains induce SsrA tagging during translation termination.

  The Journal of biological chemistry 20020913

• The structure of an endomorphin analogue incorporating 1-aminocyclohexane-1-carboxlylic acid for proline is similar to the beta-turn of Leu-enkephalin.

  Biochemical and biophysical research communications 20020913

• Synthesis of an L-proline modified mimetic of the A83586C antitumour cyclodepsipeptide.

  Chemical communications (Cambridge, England) 20020907

• Synthesis of 2,4-methanoproline analogues via an addition-intramolecular substitution sequence.

  The Journal of organic chemistry 20020906

• Complex-induced proximity effects. Temperature-dependent regiochemical diversity in lithiation-electrophilic substitution reactions of N-BOC-2-azabicyclo[2.1.1]hexane. 2,4- and 3,5-methanoprolines.

  Organic letters 20020905

• Inhibitors of metalloendopeptidase EC 3.4.24.15 and EC 3.4.24.16 stabilized against proteolysis by the incorporation of beta-amino acids.

  Biochemistry 20020903

• Conformational dynamics of helix S6 from Shaker potassium channel: simulation studies.

  Biopolymers 20020901

• Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes.

  Kidney international 20020901

• Drug testing in blood: validated negative-ion chemical ionization gas chromatographic-mass spectrometric assay for determination of amphetamine and methamphetamine enantiomers and its application to toxicology cases.

  Clinical chemistry 20020901

• Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues.

  Gastroenterology 20020901

• Identification of crucial residues for the antibacterial activity of the proline-rich peptide, pyrrhocoricin.

  European journal of biochemistry 20020901

• Influence of structure and chirality of the selector on the chiral recognition of amino acids using ligand-exchange capillary electrophoresis.

  Electrophoresis 20020901

• Epithelial barrier function: assembly and structural features of the cornified cell envelope.

  BioEssays : news and reviews in molecular, cellular and developmental biology 20020901

• Regional alterations of type I collagen in rat tibia induced by skeletal unloading.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020901

• In vitro quantitative study of the degradation of endomorphins.

  Peptides 20020901

• Does proline accumulation play an active role in stress-induced growth reduction?

  The Plant journal : for cell and molecular biology 20020901

• [Morphological changes responding to abiotic environmental stress].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20020901

• The (beta)gamma subunits of G proteins gate a K(+) channel by pivoted bending of a transmembrane segment.

  Molecular cell 20020901

• [In vitro study of the apoptosis effect of DNR on HL-60 cells and its relationship with ROS, CER and NF-kappaB].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20020901

• [Stress effects of simulant acid rain on three woody plants].

  Huan jing ke xue= Huanjing kexue 20020901

• [Experimental study on rabbit periosteal osteoblasts and renal vascular endothelial cells indirect co-culture in vitro].

  Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20020901

• IL-2 receptor signaling through the Shb adapter protein in T and NK cells.

  Biochemical and biophysical research communications 20020830

• DNA damage, death receptor activation and reactive oxygen species contribute to ultraviolet radiation-induced apoptosis in an essential and independent way.

  Oncogene 20020829

• Quantitative model studies on the efficiency of precursors in the formation of cooling-active 1-pyrrolidinyl-2-cyclopenten-1-ones and bitter-tasting cyclopenta-[b]azepin-8(1H)-ones.

  Journal of agricultural and food chemistry 20020828

• Rotenone-insensitive NADH dehydrogenase is a potential source of superoxide in procyclic Trypanosoma brucei mitochondria.

  Molecular and biochemical parasitology 20020828

• A conserved cis peptide bond is necessary for the activity of Bowman-Birk inhibitor protein.

  Biochemistry 20020827

• An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells.

  Biochemical and biophysical research communications 20020823

• Regio- and stereoselective synthesis of (E)-alkene trans-Xaa-Pro dipeptide mimetics utilizing organocopper-mediated anti-S(N)2' reactions.

  The Journal of organic chemistry 20020823

• Diastereoselective synthesis of new psi[(E)-CH=CMe]- and psi[(Z)-CH=CMe]-type alkene dipeptide isosteres by organocopper reagents and application to conformationally restricted cyclic RGD peptidomimetics.

  The Journal of organic chemistry 20020823

• Synthesis of the pro-gly dipeptide alkene isostere using olefin cross-metathesis.

  The Journal of organic chemistry 20020823

• Lanthanide Lewis acid-mediated enantioselective conjugate radical additions.

  Organic letters 20020822

• Multiple conformations of the proline-rich protein/epigallocatechin gallate complex determined by time-averaged nuclear Overhauser effects.

  Journal of the American Chemical Society 20020821

• Tandem mass spectrometry for structural characterization of proline-rich proteins: application to salivary PRP-3.

  Analytical chemistry 20020815

• The proline rich region of the Tec homology domain of ITK regulates its activity.

  FEBS letters 20020814

• Stereoselective synthesis of unnatural spiroisoxazolinoproline-based amino acids and derivatives.

  The Journal of organic chemistry 20020809

• Highly diastereoselective desymmetrizations of cyclo(Pro,Pro): an enantioselective strategy toward phakellstatin and phakellin.

  Organic letters 20020808

• Structural evidence that the P/Q domain of ZipA is an unstructured, flexible tether between the membrane and the C-terminal FtsZ-binding domain.

  Journal of bacteriology 20020801

• The antifungal drug ciclopirox inhibits deoxyhypusine and proline hydroxylation, endothelial cell growth and angiogenesis in vitro.

  International journal of cancer 20020801

• Spatial analysis of ocular dominance patterns in monocularly deprived cats.

  Cerebral cortex (New York, N.Y. : 1991) 20020801

• Supramolecular properties of the proline-rich gamma-Zein N-terminal domain.

  Biophysical journal 20020801

• Proline biosynthesis genes and their regulation under salinity stress in the euryhaline copepod Tigriopus californicus.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020801

• The intracellular loops of the GB2 subunit are crucial for G-protein coupling of the heteromeric gamma-aminobutyrate B receptor.

  Molecular pharmacology 20020801

• Synthesis of N-glyoxyl prolyl and pipecolyl amides and thioesters and evaluation of their in vitro and in vivo nerve regenerative effects.

  Journal of medicinal chemistry 20020801

• Synthesis of ketone analogues of prolyl and pipecolyl ester FKBP12 ligands.

  Journal of medicinal chemistry 20020801

• HPV16/18 prevalence in cervical lesions/cancers and p53 genotypes in cervical cancer patients from India.

  Gynecologic oncology 20020801

• The peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism.

  Diabetes 20020801

• Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study.

  Diabetes 20020801

• Peroxisome proliferator-activated receptor-gamma2 polymorphism Pro12Ala is associated with nephropathy in type 2 diabetes: The Berlin Diabetes Mellitus (BeDiaM) Study.

  Diabetes 20020801

• The Pro115Gln polymorphism within the PPAR gamma2 gene has no epidemiological impact on morbid obesity.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20020801

• Peripheral group II metabotropic glutamate receptors (mGluR2/3) regulate prostaglandin E2-mediated sensitization of capsaicin responses and thermal nociception.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020801

• The (ProB27, ThrB28) human insulin analogue is more potent and more rapidly absorbed from subcutis than human insulin.

  European journal of endocrinology 20020801

• Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: homozygosity of the Ala allele confers a decreased risk of the insulin resistance syndrome.

  The Journal of clinical endocrinology and metabolism 20020801

• Effect of supplemental ornithine on wound healing.

  The Journal of surgical research 20020801

• Up-regulation of CD13/aminopeptidase N induced by phorbol ester is involved in redox regulation and tumor necrosis factor alpha production in HL-60 cells.

  Inflammation 20020801

• Transport of cis- and trans-4-[(18)F]fluoro-L-proline in F98 glioma cells.

  Nuclear medicine and biology 20020801

• Effects of epidermal growth factor on placental amino acids uptake in pregnant rats.

  The Journal of veterinary medical science 20020801

• Structural consequences of replacement of an alpha-helical Pro residue in Escherichia coli thioredoxin.

  Protein engineering 20020801

• The epithelial mitogen keratinocyte growth factor binds to collagens via the consensus sequence glycine-proline-hydroxyproline.

  The Journal of biological chemistry 20020726

• Role of cis prolines 112 and 126 in the functional activity of ribonucleolytic toxin restrictocin.

  Biochemical and biophysical research communications 20020726

• An effective new synthesis of 4-aminopyrrole-2-carboxylates.

  Organic letters 20020725

• Recessive inheritance and variable penetrance of slow-channel congenital myasthenic syndromes.

  Neurology 20020723

• DNA ligase III is degraded by calpain during cell death induced by DNA-damaging agents.

  The Journal of biological chemistry 20020719

• A new technique to co-localise membrane proteins with Homer/vesl.

  Biochemical and biophysical research communications 20020719

• Aggregation and neurotoxicity of mutant amyloid beta (A beta) peptides with proline replacement: importance of turn formation at positions 22 and 23.

  Biochemical and biophysical research communications 20020712

• Pyrrolidine-5,5-trans-lactams as novel mechanism-based inhibitors of human cytomegalovirus protease. Part 3: potency and plasma stability.

  Bioorganic & medicinal chemistry letters 20020708

• Regulation of collagenase-3 and osteocalcin gene expression by collagen and osteopontin in differentiating MC3T3-E1 cells.

  The Journal of biological chemistry 20020705

• Conformational preferences of substituted prolines in the collagen triple helix.

  Biopolymers 20020705

• Human papillomavirus type 11 alters the transcription and expression of loricrin, the major cell envelope protein.

  Virology 20020705

• Role of protein flexibility in the catalytic cycle of p-hydroxybenzoate hydroxylase elucidated by the Pro293Ser mutant.

  Biochemistry 20020702

• TCR engagement induces proline-rich tyrosine kinase-2 (Pyk2) translocation to the T cell-APC interface independently of Pyk2 activity and in an immunoreceptor tyrosine-based activation motif-mediated fashion.

  Journal of immunology (Baltimore, Md. : 1950) 20020701

• Structure of the 1-36 N-terminal fragment of human phospholamban phosphorylated at Ser-16 and Thr-17.

  Biophysical journal 20020701

• Familial isolated hyperCKaemia associated with a new mutation in the caveolin-3 (CAV-3) gene.

  Journal of neurology, neurosurgery, and psychiatry 20020701

• The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth.

  Diabetes 20020701

• Uptake of cis-4-[18 F]fluoro-L-proline in scar formation: a marker of collagen synthesis?

  Nuclear medicine communications 20020701

• NF-kappaB p50 and p52 expression is not required for RANK-expressing osteoclast progenitor formation but is essential for RANK- and cytokine-mediated osteoclastogenesis.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020701

• Interleukin-1beta elevates cyclooxygenase-2 protein level and enzyme activity via increasing its mRNA stability in human endometrial stromal cells: an effect mediated by extracellularly regulated kinases 1 and 2.

  The Journal of clinical endocrinology and metabolism 20020701

• [PHS--a double-leaved mesh in the open surgery of inguinal hernias].

  Zentralblatt fur Chirurgie 20020701

• [Polymorphism in codon 72 of the p53 gene and cervico-uterine cancer risk in Mexico].

  Ginecologia y obstetricia de Mexico 20020701

• The short proline-rich antibacterial peptide family.

  Cellular and molecular life sciences : CMLS 20020701

• Regulation of gene expression by the hypoxia-inducible factors.

  Molecular interventions 20020701

• Toward a general strategy for the synthesis of 3,4-dihydroxyprolines from pentose sugars.

  The Journal of organic chemistry 20020628

• Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation.

  Cell 20020628

• The mechanism of cis-trans isomerization of prolyl peptides by cyclophilin.

  Journal of the American Chemical Society 20020626

• Key motif to gain selectivity at the neuropeptide Y5-receptor: structure and dynamics of micelle-bound [Ala31, Pro32]-NPY.

  Biochemistry 20020625

• Scanning mutagenesis of a Janus-faced atracotoxin reveals a bipartite surface patch that is essential for neurotoxic function.

  The Journal of biological chemistry 20020621

• Active site residues of cyclophilin A are crucial for its signaling activity via CD147.

  The Journal of biological chemistry 20020621

• A short segment of the R domain of cystic fibrosis transmembrane conductance regulator contains channel stimulatory and inhibitory activities that are separable by sequence modification.

  The Journal of biological chemistry 20020621

• Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters.

  The Journal of biological chemistry 20020621

• Organization of an efficient carbonic anhydrase: implications for the mechanism based on structure-function studies of a T199P/C206S mutant.

  Biochemistry 20020618

• How oxygen makes its presence felt.

  Genes & development 20020615

• Proline metabolism and transport in maize seedlings at low water potential.

  Annals of botany 20020615

• Biochemical defects in retina-specific human ATP binding cassette transporter nucleotide binding domain 1 mutants associated with macular degeneration.

  The Journal of biological chemistry 20020614

• Role of the proline-rich domain of dynamin-2 and its interactions with Src homology 3 domains during endocytosis of the AT1 angiotensin receptor.

  The Journal of biological chemistry 20020614

• Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling.

  The Journal of biological chemistry 20020614

• Incorporation of Ahc into model dipeptides as an inducer of a beta-turn with a distorted amide bond. Conformational analysis.

  The Journal of organic chemistry 20020614

• Endomorphin-1 analogues containing beta-proline are mu-opioid receptor agonists and display enhanced enzymatic hydrolysis resistance.

  Journal of medicinal chemistry 20020606

• Impact of four (13)C-proline isotope labels on the infrared spectra of ribonuclease T1.

  Journal of the American Chemical Society 20020605

• Disruption of the alpha5 helix of transducin impairs rhodopsin-catalyzed nucleotide exchange.

  Biochemistry 20020604

• Functional role of the prokaryotic proline-tRNA synthetase insertion domain in amino acid editing.

  Biochemistry 20020604

• A plant for all seasons: alterations in photosynthetic carbon metabolism during cold acclimation in Arabidopsis.

  Current opinion in plant biology 20020601

• Enhancement of tolerance of abiotic stress by metabolic engineering of betaines and other compatible solutes.

  Current opinion in plant biology 20020601

• IL-17 stimulates inflammatory responses via NF-kappaB and MAP kinase pathways in human colonic myofibroblasts.

  American journal of physiology. Gastrointestinal and liver physiology 20020601

• ATA2 is predominantly expressed as system A at the blood-brain barrier and acts as brain-to-blood efflux transport for L-proline.

  Molecular pharmacology 20020601

• The dynamics, structure, and conformational free energy of proline-containing antifreeze glycoprotein.

  Biophysical journal 20020601

• Influence of the environment in the conformation of alpha-helices studied by protein database search and molecular dynamics simulations.

  Biophysical journal 20020601

• Cross-reactivities between date palm (Phoenix dactylifera L.) polypeptides and foods implicated in the oral allergy syndrome.

  Allergy 20020601

• Substitution of isoleucine-31 by helical-breaking proline abolishes oxidative stress and neurotoxic properties of Alzheimer's amyloid beta-peptide.

  Free radical biology & medicine 20020601

• Tumor-targeted delivery of polyethylene glycol-conjugated D-amino acid oxidase for antitumor therapy via enzymatic generation of hydrogen peroxide.

  Cancer research 20020601

• Potential role of nuclear factor kappaB and reactive oxygen species in cAMP and cytokine regulation of surfactant protein-A gene expression in lung type II cells.

  Molecular endocrinology (Baltimore, Md.) 20020601

• [Association of Pro12Ala variant in peroxisome proliferator-activated receptor-gamma2 gene with type 2 diabetes mellitus].

  Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20020601

• Is a Pro12Ala polymorphism of the PPARgamma2 gene related to obesity and type 2 diabetes mellitus in the Czech population?

  Annals of the New York Academy of Sciences 20020601

• The single nucleotide polymorphism T1128C in the signal peptide of neuropeptide Y (NPY) was not identified in a Korean population.

  Journal of clinical pharmacy and therapeutics 20020601

• Humectant permeability influences growth and compatible solute uptake by Staphylococcus aureus subjected to osmotic stress.

  Journal of food protection 20020601

• The measurement of insulin-like growth factor-I (IGF-I) concentration in random urine samples.

  Clinical chemistry and laboratory medicine 20020601

• Dental biofilms at healthy and inflamed gingival margins.

  Journal of clinical periodontology 20020601

• Effect of dietary amino acids on behavior and serum levels of amino acids in stress loaded rats.

  Journal of nutritional science and vitaminology 20020601

• Novel dipeptide macrocycles from 4-oxo, -thio, and -amino-substituted proline derivatives.

  The Journal of organic chemistry 20020531

• Functional characterization of betaine/proline transporters in betaine-accumulating mangrove.

  The Journal of biological chemistry 20020524

• Quantification of the influence of HPrSer46P on CcpA-cre interaction.

  Journal of molecular biology 20020524

• Hsc62, Hsc56, and GrpE, the third Hsp70 chaperone system of Escherichia coli.

  Biochemical and biophysical research communications 20020524

• Direct catalytic asymmetric alpha-amination of aldehydes.

  Journal of the American Chemical Society 20020522

• Structural consequences of tumor-derived mutations in p16INK4a probed by limited proteolysis.

  Biochemistry 20020521

• Pale cytochrome oxidase stripes in V2 receive the richest projection from macaque striate cortex.

  The Journal of comparative neurology 20020520

• Structural characterization of the M* partly folded intermediate of wild type and P138A aspartate aminotransferase from Escherichia coli.

  The Journal of biological chemistry 20020517

• Structural mimicry of proline kinks: tertiary packing interactions support local structural distortions.

  Journal of molecular biology 20020517

• Direct organo-catalytic asymmetric alpha-amination of aldehydes--a simple approach to optically active alpha-amino aldehydes, alpha-amino alcohols, and alpha-amino acids.

  Angewandte Chemie (International ed. in English) 20020517

• Modulation of triple-helical stability and subsequent melanoma cellular responses by single-site substitution of fluoroproline derivatives.

  Biochemistry 20020514

• Differential role of the proline-rich domain of nuclear factor 1-C splice variants in DNA binding and transactivation.

  The Journal of biological chemistry 20020510

• Recognition of hybrid peptidyl carrier proteins/acyl carrier proteins in nonribosomal peptide synthetase modules by the 4'-phosphopantetheinyl transferases AcpS and Sfp.

  The Journal of biological chemistry 20020510

• A kinetic model of intermediate formation during assembly of cholera toxin B-subunit pentamers.

  The Journal of biological chemistry 20020510

• Acid-labile formylation of amino terminal proline of human immunodeficiency virus type 1 p24(gag) was found by proteomics using two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry.

  Biochemical and biophysical research communications 20020510

• Sequence conservation in Ig-like domains: the role of highly conserved proline residues in the fibronectin type III superfamily.

  Journal of molecular biology 20020510

• Crystal structure of the Homer 1 family conserved region reveals the interaction between the EVH1 domain and own proline-rich motif.

  Journal of molecular biology 20020510

• Structure-activity relationships for mini atrial natriuretic peptide by proline-scanning mutagenesis and shortening of peptide backbone.

  Bioorganic & medicinal chemistry letters 20020506

• A solid-phase synthetic route to unnatural amino acids with diverse side-chain substitutions.

  The Journal of organic chemistry 20020503

• Stereoselective synthesis of Boc-protected cis and trans-4-trifluoromethylprolines by asymmetric hydrogenation reactions.

  Angewandte Chemie (International ed. in English) 20020503

• Asymmetric synthesis of substituted prolines from delta-amino beta-ketoesters. Methyl (2S,5R)-(+)-5-phenylpyrrolidine-2-carboxylate.

  Organic letters 20020502

• 1H-NMR parameters of common amino acid residues measured in aqueous solutions of the linear tetrapeptides Gly-Gly-X-Ala at pressures between 0.1 and 200 MPa.

  Biophysical chemistry 20020502

• Local structural changes caused by peptidyl-prolyl cis/trans isomerization in the native state of proteins.

  Biophysical chemistry 20020502

• Synthesis of potential thrombin inhibitors. Incorporation of tartaric acid templates as P2 proline mimetics.

  Bioorganic & medicinal chemistry 20020501

• A protein sequence that can encode native structure by disfavoring alternate conformations.

  Nature structural biology 20020501

• The critical role of transmembrane prolines in human prostacyclin receptor activation.

  Molecular pharmacology 20020501

• Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure.

  Blood 20020501

• Putting the beta-breaks on membrane protein misfolding.

  Nature structural biology 20020501

• Proacrosin-deficient mice and zona pellucida modifications in an experimental model of multifactorial infertility.

  Molecular human reproduction 20020501

• Beetles' choice--proline for energy output: control by AKHs.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020501

• Differences in collagen production between normal and keloid-derived fibroblasts in serum-media co-culture with keloid-derived keratinocytes.

  Journal of dermatological science 20020501

• A plant gene up-regulated at rust infection sites.

  Plant physiology 20020501

• Cis-trans signatures of proline-containing tryptic peptides in the gas phase.

  Analytical chemistry 20020501

• Modelling the structure of the fusion protein from human respiratory syncytial virus.

  Protein engineering 20020501

• [Effect of the bonding amounts of chiral ligand exchange chromatographic stationary phases on the enantioseparation of amino acids].

  Se pu = Chinese journal of chromatography 20020501

• A simple method for focally delivering multiple drugs or ligands to cells.

  Journal of neuroscience methods 20020430

• A 15N NMR mobility study on the dicalcium P43M calbindin D9k and its mono-La3+-substituted form.

  Biochemistry 20020423

• SmI(2)-mediated cyclizations of derivatized beta-lactams for the highly diastereoselective construction of functionalized prolines.

  The Journal of organic chemistry 20020419

• Syntheses of novel 4-tert-alkyl ether proline-based 16- and 17-membered macrocyclic compounds.

  The Journal of organic chemistry 20020419

• Crystal structure of the V-region of Streptococcus mutans antigen I/II at 2.4 A resolution suggests a sugar preformed binding site.

  Journal of molecular biology 20020419

• Myocardial fibrosis in chronic aortic regurgitation: molecular and cellular responses to volume overload.

  Circulation 20020416

• Interaction between Btk TH and SH3 domain.

  Biopolymers 20020415

• Electron transfer studies on self-assembled monolayers of helical ferrocenoyl-oligoproline-cystamine bound to gold.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20020415

• Transthyretin fibrillogenesis entails the assembly of monomers: a molecular model for in vitro assembled transthyretin amyloid-like fibrils.

  Journal of molecular biology 20020412

• Folding kinetics of the protein pectate lyase C reveal fast-forming intermediates and slow proline isomerization.

  Biochemistry 20020409

• Identification of proline residues responsible for the slow folding kinetics in pectate lyase C by mutagenesis.

  Biochemistry 20020409

• Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway.

  The Journal of biological chemistry 20020405

• Conformational studies of cyclic enkephalin analogues with L- or D-proline in position 3.

  Biopolymers 20020405

• Non-sequence-specific DNA binding by the FILAMENTOUS FLOWER protein from Arabidopsis thaliana is reduced by EDTA.

  The Journal of biological chemistry 20020405

• Effect of multivalency on the performance of enantioselective separation media for chiral HPLC prepared by linking multiple selectors to a porous polymer support via aliphatic dendrons.

  The Journal of organic chemistry 20020405

• Studies on novel peptidomimetics having bi-directional dispositions of hydroxylated D-Pro-Gly motifs anchored on a C(2)-symmetric iminosugar-based foundation.

  The Journal of organic chemistry 20020405

• Two-dimensional (13)C-(13)C correlation spectroscopy with magic angle spinning and dynamic nuclear polarization.

  Journal of the American Chemical Society 20020403

• Aqueous aldol catalysis by a nicotine metabolite.

  Journal of the American Chemical Society 20020403

• Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma2 (PPARgamma2) is associated with higher levels of total cholesterol and LDL-cholesterol in male caucasian type 2 diabetes patients.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20020401

• The role of proline in osmoregulation in Phytophthora nicotianae.

  Fungal genetics and biology : FG & B 20020401

• Catecholamines block 2-hydroxyestradiol-induced antimitogenesis in mesangial cells.

  Hypertension (Dallas, Tex. : 1979) 20020401

• Pinning down proline-directed phosphorylation signaling.

  Trends in cell biology 20020401

• Role of Ca2+ in drought stress signaling in wheat seedlings.

  Biochemistry. Biokhimiia 20020401

• Prolidase deficiency with hyperimmunoglobulin E: a case report.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20020401

• Activin A increases the bone mass of grafted bone in C3H/HeJ mice.

  Calcified tissue international 20020401

• Sequential extracts of human bone show differing collagen synthetic rates.

  Biochemical Society transactions 20020401

• Induction of iNOS expression in skeletal muscle by IL-1beta and NFkappaB activation: an in vitro and in vivo study.

  Cardiovascular research 20020401

• [Study on the relationship between cervical cancer and p53 codon 72 polymorphism].

  Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20020401

• An N-terminal arginine-rich cluster and a proline-alanine-threonine repeat region determine the cellular localization of the herpes simplex virus type 1 ICP34.5 protein and its ligand, protein phosphatase 1.

  The Journal of biological chemistry 20020329

• Influence of silaproline on peptide conformation and bioactivity.

  Journal of the American Chemical Society 20020327

• Precursors of 2-acetyl-1-pyrroline, a potent flavor compound of an aromatic rice variety.

  Journal of agricultural and food chemistry 20020327

• Repression of the 14-3-3 gene affects the amino acid and mineral composition of potato tubers.

  Journal of agricultural and food chemistry 20020327

• Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A 'knock-out' allosteric enzyme.

  The Journal of biological chemistry 20020322

• The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression.

  The Journal of biological chemistry 20020322

• Effect of sequence on peptide geometry in 5-tert-butylprolyl type VI beta-turn mimics.

  Journal of the American Chemical Society 20020320

• Collagen stability: insights from NMR spectroscopic and hybrid density functional computational investigations of the effect of electronegative substituents on prolyl ring conformations.

  Journal of the American Chemical Society 20020320

• [Genetics of blood coagulation in young stroke patients].

  Ideggyogyaszati szemle 20020320

• Sites important for Na+ and substrate binding in the Na+/proline transporter of Escherichia coli, a member of the Na+/solute symporter family.

  The Journal of biological chemistry 20020315

• A conserved proline residue is present in the transmembrane-spanning domain of Tom7 and other tail-anchored protein subunits of the TOM translocase.

  FEBS letters 20020313

• Helix D elongation and allosteric activation of antithrombin.

  The Journal of biological chemistry 20020308

• Structure function analysis of interleukin 7: requirement for an aromatic ring at position 143 of helix D.

  Cytokine 20020307

• A highly enantioselective route to either enantiomer of both alpha- and beta-amino acid derivatives.

  Journal of the American Chemical Society 20020306

• Cysteinyl-tRNA formation and prolyl-tRNA synthetase.

  FEBS letters 20020306

• Altered regulation of SHP-2 and PTP 1B tyrosine phosphatases in cystic kidneys from bcl-2 -/- mice.

  American journal of physiology. Renal physiology 20020301

• A novel proline rich bombesin-related peptide (PR-bombesin) from toad Bombina maxima.

  Peptides 20020301

• Proline metabolism and NAD kinase activity in greenbean plants subjected to cold-shock.

  Phytochemistry 20020301

• Structure, genomic DNA typing, and kinetic characterization of the D allozyme of placental alkaline phosphatase (PLAP/ALPP).

  Human mutation 20020301

• Identification of a novel NOG gene mutation (P35S) in an Italian family with symphalangism.

  Human mutation 20020301

• Free amino acids in claw muscle and haemolymph from Australian freshwater crayfish at different stages of the moult cycle.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020301

• The proline 12 alanine substitution in the peroxisome proliferator--activated receptor-gamma2 gene is associated with lower lipoprotein lipase activity in vivo.

  Diabetes 20020301

• Cis-4-[(18)F]fluoro-L-proline PET imaging of pulmonary fibrosis in a rabbit model.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20020301

• A novel 196Leu to Pro substitution in the beta3 subunit of the alphaIIbbeta3 integrin in a patient with a variant form of Glanzmann thrombasthenia.

  Platelets 20020301

• Association of leucine 7 to proline 7 polymorphism in the preproneuropeptide Y with serum lipids in patients with coronary heart disease.

  Molecular genetics and metabolism 20020301

• A novel mutation of the cathepsin C gene in Papillon-Lefèvre syndrome.

  Journal of periodontology 20020301

• Gelria glutamica gen. nov., sp. nov., a thermophilic, obligately syntrophic, glutamate-degrading anaerobe.

  International journal of systematic and evolutionary microbiology 20020301

• Screening and modulation of extracellular signals by mucous barrier. Serum glycosylphosphatidylinositol phospholipase D (GPI-PLD) releases protective mucous barrier from oral mucosa.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20020301

• Mutation of the GABAA receptor M1 transmembrane proline increases GABA affinity and reduces barbiturate enhancement.

  Neuropharmacology 20020301

• Changes in collagen matrix composition in human posterior tibial tendon dysfunction.

  Joint, bone, spine : revue du rhumatisme 20020301

• Flow cytometry as a useful tool for process development: rapid evaluation of expression systems.

  Journal of biotechnology 20020227

• Interactions between flavonoids and proteins: effect on the total antioxidant capacity.

  Journal of agricultural and food chemistry 20020227

• Amino acid activation of a dual-specificity tRNA synthetase is independent of tRNA.

  Journal of molecular biology 20020222

• WW and SH3 domains, two different scaffolds to recognize proline-rich ligands.

  FEBS letters 20020220

• EVH1 domains: structure, function and interactions.

  FEBS letters 20020220

• Cadmium resistance conferred to yeast by a non-metallothionein-encoding gene of the earthworm Enchytraeus.

  The Journal of biological chemistry 20020215

• Effects of osmoprotectant compounds on NCAM polysialylation under hyperosmotic stress and elevated pCO(2).

  Biotechnology and bioengineering 20020215

• Comparison of the folding processes of T. thermophilus and E. coli ribonucleases H.

  Journal of molecular biology 20020215

• Inhibition of hepatic stellate cell collagen synthesis by N-(methylamino)isobutyric acid.

  Biochemical pharmacology 20020215

• Kinetic control of proline amide rotamers: total synthesis of trans,trans- and cis,cis-ceratospongamide.

  Journal of the American Chemical Society 20020213

• Involvement of the N-terminus of Bax in its intracellular localization and function.

  FEBS letters 20020213

• Characterization of the cellular and metabolic effects of a novel enzyme-resistant antagonist of glucose-dependent insulinotropic polypeptide.

  Biochemical and biophysical research communications 20020208

• Enantioselective synthesis of (2S,3R)-3-hydroxy-3-methylproline, a novel amino acid found in polyoxypeptins.

  The Journal of organic chemistry 20020208

• A new and short method for the synthesis of 2,4-methanoproline.

  Chemical communications (Cambridge, England) 20020207

• The proline-catalyzed direct asymmetric three-component Mannich reaction: scope, optimization, and application to the highly enantioselective synthesis of 1,2-amino alcohols.

  Journal of the American Chemical Society 20020206

• Allelic variation in the highly polymorphic locus pspC of Streptococcus pneumoniae.

  Gene 20020206

• Rapid screening of urinary proline-hydroxyproline dipeptide in bone turnover studies.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020205

• Crystal structure of the collagen triple helix model [(Pro-Pro-Gly)(10)](3).

  Protein science : a publication of the Protein Society 20020201

• Doing (F/L)PPPPs: EVH1 domains and their proline-rich partners in cell polarity and migration.

  Current opinion in cell biology 20020201

• Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein.

  Human mutation 20020201

• C-terminal anchoring of a peptide to class II MHC via the P10 residue is compatible with a peptide bulge.

  Journal of immunology (Baltimore, Md. : 1950) 20020201

• Effect of osmolytes as folding aids on creatine kinase refolding pathway.

  The international journal of biochemistry & cell biology 20020201

• Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch.

  Science (New York, N.Y.) 20020201

• Prevention of mis-aminoacylation of a dual-specificity aminoacyl-tRNA synthetase.

  Journal of molecular biology 20020201

• Spastic paraparesis and atypical dementia caused by PSEN1 mutation (P264L), responsible for Alzheimer's disease.

  Journal of medical genetics 20020201

• [p53 gene codon 72 polymorphism and susceptibility to esophageal squamous cell carcinoma in a Chinese population].

  Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20020201

• The impact of the leucine 7 to proline 7 polymorphism of the neuropeptide Y gene on postprandial lipemia and on the response of serum total and lipoprotein lipids to a reduced fat diet.

  European journal of clinical nutrition 20020201

• Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling.

  Development (Cambridge, England) 20020201

• Conversion of L-proline to pyrrolyl-2-carboxyl-S-PCP during undecylprodigiosin and pyoluteorin biosynthesis.

  Chemistry & biology 20020201

• Insights on the conformational stability of collagen.

  Natural product reports 20020201

• Quantum mechanical study of the conformational behavior of proline and 4R-hydroxyproline dipeptide analogues in vacuum and in aqueous solution.

  Journal of computational chemistry 20020201

• Regulation of p73 by c-Abl through the p38 MAP kinase pathway.

  Oncogene 20020131

• Determination of active site residues in Escherichia coli endonuclease VIII.

  The Journal of biological chemistry 20020125

• PRiMA: the membrane anchor of acetylcholinesterase in the brain.

  Neuron 20020117

• Differential induction of mafF, mafG and mafK expression by electrophile-response-element activators.

  The Biochemical journal 20020115

• Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif.

  The EMBO journal 20020115

• Proline-catalyzed one-step asymmetric synthesis of 5-hydroxy-(2E)-hexenal from acetaldehyde.

  The Journal of organic chemistry 20020111

• Differential effect of brefeldin A on the palmitoylation of surfactant protein C proprotein mutants.

  Biochemical and biophysical research communications 20020111

• Folding of the yeast prion protein Ure2: kinetic evidence for folding and unfolding intermediates.

  Journal of molecular biology 20020111

• The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells.

  Oncogene 20020103

• Differing substrate specificities of members of the DYRK family of arginine-directed protein kinases.

  FEBS letters 20020102

• Competing modes of self-association in the regulatory domains of Bruton's tyrosine kinase: intramolecular contact versus asymmetric homodimerization.

  Protein science : a publication of the Protein Society 20020101

• Effect of temperature on dietary vitamin C requirement and lipid in common carp.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020101

• Mutations throughout the S6 region of the hKv1.5 channel alter the stability of the activation gate.

  American journal of physiology. Cell physiology 20020101

• Determination of phenoxyacid herbicides and their phenolic metabolites in surface and drinking water.

  Rapid communications in mass spectrometry : RCM 20020101

• Effects of replacement of prolines with alanines on the catalytic activity and thermostability of inorganic pyrophosphatase from thermophilic bacterium PS-3.

  Journal of biochemistry 20020101

• Role of group II and group III metabotropic glutamate receptors in spinal cord injury.

  Experimental neurology 20020101

• The proton affinity of proline analogs using the kinetic method with full entropy analysis.

  Journal of the American Society for Mass Spectrometry 20020101

• The proline form of p53 codon 72 polymorphism is associated with endometriosis.

  Fertility and sterility 20020101

• Proline-rich transcript of the brain (prtb) is a serum-responsive gene in osteoblasts and upregulated during adhesion.

  Journal of cellular biochemistry 20020101

• Altered levels of proline dehydrogenase cause hypersensitivity to proline and its analogs in Arabidopsis.

  Plant physiology 20020101

• Prognostic significance of the proline form of p53 codon 72 polymorphism in nasopharyngeal carcinoma.

  The Laryngoscope 20020101

• Vibrational spectrum of methyl pyrrole-2-carboxylate.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20020101

• Non-protein amino acids of Bocoa (Leguminosae; Papilionoideae).

  Phytochemistry 20020101

• Repair of oxidized purines and damaged pyrimidines by E. coli Fpg protein: different roles of proline 2 and lysine 57 residues.

  Environmental and molecular mutagenesis 20020101

• Predominant role by CaM kinase in NPY Y(1) receptor signaling: involvement of CREB [corrected].

  Peptides 20020101

• Characterization of the aryl hydrocarbon receptor repressor gene and association of its Pro185Ala polymorphism with micropenis.

  Teratology 20020101

• Angiotensin II induced inflammation in the kidney and in the heart of double transgenic rats.

  BMC cardiovascular disorders 20020101

• The effect of proline insertions on the thermostability of a barley alpha-glucosidase.

  Protein engineering 20020101

• Reduced lipolysis as possible cause for greater weight gain in subjects with the Pro12Ala polymorphism in PPARgamma2?

  Diabetologia 20020101

• PPARgamma2 pro12Ala polymorphism and insulin resistance in Japanese hypertensive patients.

  Hypertension research : official journal of the Japanese Society of Hypertension 20020101

• Pro-rich antimicrobial peptides from animals: structure, biological functions and mechanism of action.

  Current pharmaceutical design 20020101

• In vivo metabolism and clearance of substance P and co-expressed tachykinins in rat striatum.

  Neuroscience 20020101

• Time-resolved FTIR difference spectroscopy as tool for investigating refolding reactions of ribonuclease T1 synchronized with trans --> cis prolyl isomerization.

  Biopolymers 20020101

• Analysis of the kefA2 mutation suggests that KefA is a cation-specific channel involved in osmotic adaptation in Escherichia coli.

  Molecular microbiology 20020101

• [Neuroleptic-like activity of the tripeptide neurotensin analog GZR-123].

  Eksperimental'naia i klinicheskaia farmakologiia 20020101

• [Effect of dermorphin analogs on thermoregulation of rats under various thermal conditions].

  Izvestiia Akademii nauk. Seriia biologicheskaia 20020101

• Testosterone is a potential augmentor of antioxidant-induced apoptosis in human prostate cancer cells.

  Cancer detection and prevention 20020101

• Diabetic ketoacidosis depletes plasma tryptophan.

  Endocrine research 20020101

• Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex.

  Advances in enzyme regulation 20020101

• New example of proline-induced fragmentation in electrospray ionization mass spectrometry of peptides.

  Rapid communications in mass spectrometry : RCM 20020101

• Oral mucosal immunity and HIV infection: current status.

  Oral diseases 20020101

• [Effect of structural changes of Pro6 in dermorphin molecule on its antinociceptive activity].

  Izvestiia Akademii nauk. Seriia biologicheskaia 20020101

• Salt stress response and proline accumulation in Brachiaria humidicola plants with and without mycorrhizal inoculation.

  Revista Argentina de microbiologia 20020101

• The analgesic domain of interferon-alpha2b contains an essential proline(39) residue.

  Neuroimmunomodulation 20020101

• Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is associated with increased leptin levels in women with type-2 diabetes mellitus.

  Hormone research 20020101

• Mutational analyses of the signals involved in the subcellular location of DSCR1.

  BMC cell biology 20020101

• Inhibition of nuclear factor kappaB induces apoptosis following treatment with tumor necrosis factor alpha and an antioxidant in human prostate cancer cells.

  Cancer detection and prevention 20020101

• The PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulator.

  BMC biochemistry 20020101

• Haplotype analysis of the PPARgamma Pro12Ala and C1431T variants reveals opposing associations with body weight.

  BMC genetics 20020101

• Electroretinographic findings in three family members with X-linked juvenile retinoschisis associated with a novel Pro192Thr mutation of the XLRS1 gene.

  Japanese journal of ophthalmology 20020101

• How SH3 domains recognize proline.

  Advances in protein chemistry 20020101

• Active transport of L-proline in Trypanosoma cruzi.

  The Journal of eukaryotic microbiology 20020101

• [Stereochemistry of the reductive amination of 4-oxoproline derivatives with glycine esters].

  Bioorganicheskaia khimiia 20020101

• TP53 codon 72 polymorphism in oral squamous cell carcinoma.

  Anticancer research 20020101

• Altered expression of cardiac ankyrin repeat protein and its homologue, ankyrin repeat protein with PEST and proline-rich region, in atrophic muscles in amyotrophic lateral sclerosis.

  Pathobiology : journal of immunopathology, molecular and cellular biology 20020101

• Endogenous prolyl 4-hydroxylation in Hansenula polymorpha and its use for the production of hydroxylated recombinant gelatin.

  FEMS yeast research 20020101

• The origin of stereoselectivity in proline-catalyzed intramolecular aldol reactions.

  Journal of the American Chemical Society 20011226

• The small 11-kDa protein from B19 parvovirus binds growth factor receptor-binding protein 2 in vitro in a Src homology 3 domain/ligand-dependent manner.

  Virology 20011220

• Understanding the role of stereoelectronic effects in determining collagen stability. 1. A quantum mechanical study of proline, hydroxyproline, and fluoroproline dipeptide analogues in aqueous solution.

  Journal of the American Chemical Society 20011219

• Very strong C-H...O, N-H...O, and O-H...O hydrogen bonds involving a cyclic phosphate.

  Journal of the American Chemical Society 20011219

• Apoflavodoxin folding mechanism: an alpha/beta protein with an essentially off-pathway intermediate.

  Biochemistry 20011218

• Differential association of the codon 72 p53 and GSTM1 polymorphisms on histological subtype of non-small cell lung carcinoma.

  Cancer research 20011215

• Dynamic association of trigger factor with protein substrates.

  Journal of molecular biology 20011214

• Compensatory changes in enzymes of arginine metabolism during renal hypertrophy in mice.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20011201

• Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism.

  Journal of immunology (Baltimore, Md. : 1950) 20011201

• Preferred proline puckerings in cis and trans peptide groups: implications for collagen stability.

  Protein science : a publication of the Protein Society 20011201

• Transforming growth factor-beta 1 stimulates vascular smooth muscle cell L-proline transport by inducing system A amino acid transporter 2 (SAT2) gene expression.

  The Biochemical journal 20011201

• Hormonal stimulation of proline synthesis in the fat body of the fruit beetle, Pachnoda sinuata, is calcium dependent.

  Insect biochemistry and molecular biology 20011201

• Much huffing about HIF: oxygen dependent proline hydroxylation and the regulation of hypoxia inducible factors.

  Pediatric research 20011201

• Isolation, quantitation, and characterization of a stable complex formed by Lp[a] binding to triglyceride-rich lipoproteins.

  Journal of lipid research 20011201

• Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases.

  European journal of biochemistry 20011201

• The characterization of a (nutritionally important) proline iminopeptidase from Eikenella corrodens.

  Oral microbiology and immunology 20011201

• Nuclear factor kappa B is involved in lipopolysaccharide-stimulated induction of interferon regulatory factor-1 and GAS/GAF DNA-binding in human umbilical vein endothelial cells.

  British journal of pharmacology 20011201

• Use of the carbonyl chemical shift to relieve degeneracies in triple-resonance assignment experiments.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20011201

• Heat labile ribonuclease HI from a psychrotrophic bacterium: gene cloning, characterization and site-directed mutagenesis.

  Protein engineering 20011201

• Association between proline-requiring auxotype and fluoroquinolone resistance in Neisseria gonorrhoeae isolated in Japan.

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20011201

• Depressor and bradycardic actions of L-proline injected into the nucleus tractus solitarii of anesthetized rats.

  The Japanese journal of physiology 20011201

• Inhibition of Na+,K+-ATPase activity from rat hippocampus by proline.

  Neurochemical research 20011201

• Prolidase deficiency diagnosed by 1H NMR spectroscopy of urine.

  Journal of inherited metabolic disease 20011201

• Angiotensin II-induced growth effects in vascular smooth muscle in cell culture and in the aortic tunica media in organ culture.

  Archives of physiology and biochemistry 20011201

• IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells.

  The Journal of biological chemistry 20011130

• Conformational and functional significance of residue proline 17 in chicken muscle adenylate kinase.

  FEBS letters 20011123

• Syndrome of coronal craniosynostosis, Klippel-Feil anomaly, and sprengel shoulder with and without Pro250Arg mutation in the FGFR3 gene.

  American journal of medical genetics 20011122

• Transport-defective mutations alter the conformation of the energy-coupling motif of an outer membrane transporter.

  Biochemistry 20011120

• Selenazolidines as novel organoselenium delivery agents.

  Bioorganic & medicinal chemistry letters 20011119

• Novel mechanism of regulation of the non-receptor protein tyrosine kinase Csk: insights from NMR mapping studies and site-directed mutagenesis.

  Journal of molecular biology 20011116

• Determination of free D-proline and D-leucine in the brains of mutant mice lacking D-amino acid oxidase activity.

  Analytical biochemistry 20011115

• A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcohols.

  The EMBO journal 20011115

• A novel acetyltransferase found in Saccharomyces cerevisiae Sigma1278b that detoxifies a proline analogue, azetidine-2-carboxylic acid.

  The Journal of biological chemistry 20011109

• Pseudoproline-containing analogues of morphiceptin and endomorphin-2: evidence for a cis Tyr-Pro amide bond in the bioactive conformation.

  Journal of medicinal chemistry 20011108

• Conversion of pyrrole to pyrrole-2-carboxylate by cells of Bacillus megaterium in supercritical CO2.

  Chemical communications (Cambridge, England) 20011107

• Proline-based P, N ligands in asymmetric allylation and the Heck reaction.

  The Journal of organic chemistry 20011102

• Amino acid residues before the hydrophobic region which are critical for membrane translocation of the N-terminal domain of synaptotagmin II.

  FEBS letters 20011102

• Calcium binding of enamel proteins and their derivatives with emphasis on the calcium-binding domain of porcine sheathlin.

  Archives of oral biology 20011101

• Extracellular matrix regulates induction of alkaline phosphatase expression by ascorbic acid in human fibroblasts.

  Journal of cellular physiology 20011101

• Solid-state NMR structure determination of melittin in a lipid environment.

  Biophysical journal 20011101

• Tissue shear deformation stimulates proteoglycan and protein biosynthesis in bovine cartilage explants.

  Archives of biochemistry and biophysics 20011101

• Inhibitory effect of a complementary peptide on ulceration in the alkali-injured rabbit cornea.

  Investigative ophthalmology & visual science 20011101

• Leucine7 to proline7 polymorphism in the preproneuropeptide Y is associated with the progression of carotid atherosclerosis, blood pressure and serum lipids in Finnish men.

  Atherosclerosis 20011101

• GSTZ1d: a new allele of glutathione transferase zeta and maleylacetoacetate isomerase.

  Pharmacogenetics 20011101

• Antioxidants increase lipopolysaccharide-stimulated TNF alpha release in murine macrophages: role for altered TNF alpha mRNA stability.

  Shock (Augusta, Ga.) 20011101

• Enhanced exercise-induced GH secretion in subjects with Pro7 substitution in the prepro-NPY.

  The Journal of clinical endocrinology and metabolism 20011101

• Placental transport of leucine, phenylalanine, glycine, and proline in intrauterine growth-restricted pregnancies.

  The Journal of clinical endocrinology and metabolism 20011101

• Sequence analysis of fibroblast growth factor receptor 2 ( FGFR2 ) in Japanese patients with craniosynostosis.

  The Journal of craniofacial surgery 20011101

• Sibling-based association study of the PPARgamma2 Pro12Ala polymorphism and metabolic variables in Chinese and Japanese hypertension families: a SAPPHIRe study. Stanford Asian-Pacific Program in Hypertension and Insulin Resistance.

  Journal of molecular medicine (Berlin, Germany) 20011101

• CheC is related to the family of flagellar switch proteins and acts independently from CheD to control chemotaxis in Bacillus subtilis.

  Molecular microbiology 20011101

• Functional analysis of salt-inducible proline transporter of barley roots.

  Plant & cell physiology 20011101

• Microtubule-targeting drugs induce bcl-2 phosphorylation and association with Pin1.

  Neoplasia (New York, N.Y.) 20011101

• Integrative cartilage repair: adhesive strength is correlated with collagen deposition.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20011101

• Biosynthetic response and mechanical properties of articular cartilage after injurious compression.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20011101

• [Correction of the stomach blood flow as a mechanism of anti-ulcer effects of short proline-containing peptides].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20011101

• [Effects of calcium on biological characteristics of wheat seedlings under ultraviolet-B radiation stress].

  Huan jing ke xue= Huanjing kexue 20011101

• [Serapharmacological effect of kangxian ruangan granula on the proliferation of hepatic stellate cells].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20011101

• Dynamic characterization of the water binding loop in the P-type cardiotoxin: implication for the role of the bound water molecule.

  Biochemistry 20011030

• Inhibition of collagen synthesis with prolyl 4-hydroxylase inhibitor improves left ventricular function and alters the pattern of left ventricular dilatation after myocardial infarction.

  Circulation 20011030

• Chemical chaperones regulate molecular chaperones in vitro and in cells under combined salt and heat stresses.

  The Journal of biological chemistry 20011026

• A simple way to measure protein refolding rates in water.

  Journal of molecular biology 20011026

• mDia-interacting protein acts downstream of Rho-mDia and modifies Src activation and stress fiber formation.

  The Journal of biological chemistry 20011019

• Influence of chirality of the preceding acyl moiety on the cis/trans ratio of the proline peptide bond.

  The Journal of organic chemistry 20011019

• A WASp-VASP complex regulates actin polymerization at the plasma membrane.

  The EMBO journal 20011015

• The role and predicted propensity of conserved proline residues in the 5-HT3 receptor.

  The Journal of biological chemistry 20011012

• Solution conformation of human apolipoprotein C-1 inferred from proline mutagenesis: far- and near-UV CD study.

  Biochemistry 20011009

• The unique proline of the Prochlorothrix hollandica plastocyanin hydrophobic patch impairs electron transfer to photosystem I.

  The Journal of biological chemistry 20011005

• Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues.

  Bioorganic & medicinal chemistry 20011001

• Site-directed mutagenesis of the putative distal helix of peroxygenase cytochrome P450.

  Archives of biochemistry and biophysics 20011001

• The role of the adapter molecule SLP-76 in platelet function.

  Oncogene 20011001

• The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway.

  Developmental cell 20011001

• Binding of external ligands onto an engineered virus capsid.

  Protein engineering 20011001

• Increased proteolytic resistance of ribonuclease A by protein engineering.

  Protein engineering 20011001

• A biochemical analysis of people with chronic fatigue who have Irlen Syndrome: speculation concerning immune system dysfunction.

  Perceptual and motor skills 20011001

• Proline-containing dipeptide GVS-111 retains nootropic activity after oral administration.

  Bulletin of experimental biology and medicine 20011001

• CAMP-dependent protein kinase inhibits proline transport across the rat renal tubular brush border membrane.

  Bioscience reports 20011001

• Amelogenin-cytokeratin 14 interaction in ameloblasts during enamel formation.

  The Journal of biological chemistry 20010928

• Synthesis of conformationally constrained arginine and ornithine analogues based on the 3-substituted pyrrolidine framework.

  The Journal of organic chemistry 20010921

• Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation.

  The EMBO journal 20010917

• Effect of single mutations on the specificity of Escherichia coli FPG protein for excision of purine lesions from DNA damaged by free radicals.

  Free radical biology & medicine 20010915

• Design and synthesis of matrix metalloproteinase inhibitors guided by molecular modeling. Picking the S(1) pocket using conformationally constrained inhibitors.

  Journal of medicinal chemistry 20010913

• Molecular basis of the length variation in the N-terminal part of Mycoplasma synoviae hemagglutinin.

  FEMS microbiology letters 20010911

• Conformational study and enantioselective, regiospecific syntheses of novel aminoxy trans-proline analogues derived from an acylnitroso Diels-Alder cycloaddition.

  The Journal of organic chemistry 20010907

• Design and synthesis of a new bicyclic dipeptide isostere.

  Chemical communications (Cambridge, England) 20010907

• Structure, histone deacetylase, and antiprotozoal activities of apicidins B and C, congeners of apicidin with proline and valine substitutions.

  Organic letters 20010906

• p53 binds the nuclear matrix in normal cells: binding involves the proline-rich domain of p53 and increases following genotoxic stress.

  Oncogene 20010906

• TGF-beta-induced p38 activation is mediated by Rac1-regulated generation of reactive oxygen species in cultured human keratinocytes.

  International journal of molecular medicine 20010901

• Proline residue 280 in the second extracellular loop (EC2) of the VPAC2 receptor is essential for the receptor structure.

  Peptides 20010901

• Cyclooxygenase-2 gene expression and regulation in human retinal pigment epithelial cells.

  Investigative ophthalmology & visual science 20010901

• Differential modulation of the D1-like- and D2-like dopamine receptor-induced locomotor responses by group II metabotropic glutamate receptors in the rat nucleus accumbens.

  Neuropharmacology 20010901

• Mechanisms of plant desiccation tolerance.

  Trends in plant science 20010901

• Copper stimulates human oral fibroblasts in vitro: a role in the pathogenesis of oral submucous fibrosis.

  Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20010901

• Effect of food shortage on the physiology and competitive abilities of sand martin (Riparia riparia) nestlings.

  The Journal of experimental biology 20010901

• Dysideaprolines A-F and barbaleucamides A-B, novel polychlorinated compounds from a Dysidea species.

  Journal of natural products 20010901

• The influence of steric interactions on the conformation and biology of oxytocin. Synthesis and analysis of penicillamine(6)-oxytocin and penicillamine(6)-5-tert-butylproline(7)-oxytocin analogs.

  The journal of peptide research : official journal of the American Peptide Society 20010901

• Chemically L-prolinamide-modified monolithic silica column for enantiomeric separation of dansyl amino acids and hydroxy acids by capillary electrochromatography and mu-high performance liquid chromatography.

  Electrophoresis 20010901

• Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) gene in relation to insulin sensitivity among glucose tolerant caucasians.

  Diabetologia 20010901

• Cytotoxicity and effect on collagen biosynthesis of proline analogue of melphalan as a prolidase-convertible prodrug in cultured human skin fibroblasts.

  Farmaco (Societa chimica italiana : 1989) 20010901

• Structural analysis of free and enzyme-bound amaranth alpha-amylase inhibitor: classification within the knottin fold superfamily and analysis of its functional flexibility.

  Protein engineering 20010901

• The first proline of PALP motif at the C terminus of presenilins is obligatory for stabilization, complex formation, and gamma-secretase activities of presenilins.

  The Journal of biological chemistry 20010831

• Probing subtle differences in the hydrogen exchange behavior of variants of the human alpha-lactalbumin molten globule using mass spectrometry.

  Journal of molecular biology 20010824

• Selective functionalization of amino acids in water: a synthetic method via catalytic C-H bond activation.

  Journal of the American Chemical Society 20010822

• Species-specific differences in amino acid editing by class II prolyl-tRNA synthetase.

  The Journal of biological chemistry 20010817

• Solution structures by 1H NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant.

  Journal of molecular biology 20010817

• Functional roles of conserved transmembrane prolines in the human VPAC(1) receptor.

  FEBS letters 20010817

• A sequential application of kinetic resolution and polymer-supported scavenging for the isolation of chiral secondary alcohols.

  The Journal of organic chemistry 20010810

• Short, highly efficient syntheses of protected 3-azido- and 4-azidoproline and their precursors.

  Organic letters 20010809

• Ammonia regulates VID30 expression and Vid30p function shifts nitrogen metabolism toward glutamate formation especially when Saccharomyces cerevisiae is grown in low concentrations of ammonia.

  The Journal of biological chemistry 20010803

• Deletion of the Src homology 3 domain and C-terminal proline-rich sequences in Bcr-Abl prevents Abl interactor 2 degradation and spontaneous cell migration and impairs leukemogenesis.

  The Journal of biological chemistry 20010803

• Metal ion effects on the cis/trans isomerization equilibrium of proline in short-chain peptides: a solution NMR study.

  Chembiochem : a European journal of chemical biology 20010803

• Structure-activity studies of ground- and transition-state analogue inhibitors of cyclophilin.

  Journal of medicinal chemistry 20010802

• Isolation and characterisation of dipeptidyl peptidase IV from Prevotella loescheii ATCC 15930.

  Archives of oral biology 20010801

• Proline-induced hinges in transmembrane helices: possible roles in ion channel gating.

  Proteins 20010801

• Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein.

  The Biochemical journal 20010801

• The potential mechanism for glutamine-induced collagen biosynthesis in cultured human skin fibroblasts.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010801

• Regulation of MARCKS and MARCKS-related protein expression in BV-2 microglial cells in response to lipopolysaccharide.

  Journal of neurochemistry 20010801

• Purification, characterization and gene expression of a glycine and proline-rich antibacterial protein family from larvae of a beetle, Allomyrina dichotoma.

  Insect molecular biology 20010801

• Wasp recruitment to the T cell:APC contact site occurs independently of Cdc42 activation.

  Immunity 20010801

• A nuclear gene encoding mitochondrial Delta-pyrroline-5-carboxylate dehydrogenase and its potential role in protection from proline toxicity.

  The Plant journal : for cell and molecular biology 20010801

• Heme oxygenase-2 interaction with metalloporphyrins: function of heme regulatory motifs.

  Antioxidants & redox signaling 20010801

• [Inhibition of glucose transporter 1 overexpression in mesangial cells by rhein].

  Zhonghua nei ke za zhi 20010801

• The inhibitory role of DOC-2/DAB2 in growth factor receptor-mediated signal cascade. DOC-2/DAB2-mediated inhibition of ERK phosphorylation via binding to Grb2.

  The Journal of biological chemistry 20010727

• Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonists.

  Brain research 20010727

• Effect of mutation of proline 93 on redox unfolding/folding of bovine pancreatic ribonuclease A.

  Biochemistry 20010724

• Structure of Ala(20) --> Pro/Pro(64) --> Ala substituted subunit c of Escherichia coli ATP synthase in which the essential proline is switched between transmembrane helices.

  The Journal of biological chemistry 20010720

• Kinetic resolution in palladium-catalyzed asymmetric allylic alkylations by a P,O ligand system.

  Organic letters 20010712

• Full-sized RanBPM cDNA encodes a protein possessing a long stretch of proline and glutamine within the N-terminal region, comprising a large protein complex.

  Gene 20010711

• Structural role of the proline residues of the beta-hinge region of p13suc1 as revealed by site-directed mutagenesis and fluorescence studies.

  Biochemistry 20010710

• Mechanism of colon cancer cell apoptosis mediated by pyropheophorbide-a methylester photosensitization.

  Oncogene 20010705

• Contribution of tertiary amides to the conformational stability of collagen triple helices.

  Biopolymers 20010701

• Role of proline, glycerol, and heparin as protein folding aids during refolding of rabbit muscle creatine kinase.

  The international journal of biochemistry & cell biology 20010701

• Positional importance of Pro53 adjacent to the Arg49-Gly50-Asp51 sequence of rhodostomin in binding to integrin alphaIIbbeta3.

  The Biochemical journal 20010701

• ER aminopeptidases generate a unique pool of peptides for MHC class I molecules.

  Nature immunology 20010701

• Identification of differentially expressed genes by the cDNA-AFLP technique during dehydration of almond (Prunus amygdalus).

  Tree physiology 20010701

• Mitochondrial adaptations to NaCl. Complex I is protected by anti-oxidants and small heat shock proteins, whereas complex II is protected by proline and betaine.

  Plant physiology 20010701

• Non-equilibrium proteins.

  Computers & chemistry 20010701

• Purification and characterization of Delta(1)-pyrroline-5-carboxylate reductase isoenzymes, indicating differential distribution in spinach (Spinacia oleracea L.) leaves.

  Plant & cell physiology 20010701

• A type-II beta-turn, proline-containing, cyclic pentapeptide as a building block for the construction of models of the cleavage site of pro-oxytocin.

  Journal of peptide science : an official publication of the European Peptide Society 20010701

• Effect of the Pro12Ala polymorphism of the PPAR-gamma2 gene on long-term weight change in Finnish non-diabetic subjects.

  Diabetologia 20010701

• A fast method for predicting amino acid mutations that lead to unfolding.

  Protein engineering 20010701

• Role of nuclear WW domains and proline-rich proteins in dinoflagellate transcription.

  Protist 20010701

• Fas ligand is targeted to secretory lysosomes via a proline-rich domain in its cytoplasmic tail.

  Journal of cell science 20010701

• [Aluminum toxicity and tolerance in wheat].

  Huan jing ke xue= Huanjing kexue 20010701

• Comparative study of modulatory effects of Semax and primary proline-containing peptides on hemostatic reactions.

  Bulletin of experimental biology and medicine 20010701

• A point mutation in nucleoside diphosphate kinase results in a deficient light response for perithecial polarity in Neurospora crassa.

  The Journal of biological chemistry 20010615

• A succession of substrate induced conformational changes ensures the amino acid specificity of Thermus thermophilus prolyl-tRNA synthetase: comparison with histidyl-tRNA synthetase.

  Journal of molecular biology 20010615

• Novel recognition mode between Vav and Grb2 SH3 domains.

  The EMBO journal 20010615

• Fluorometric determination of N-terminal prolyl dipeptides, proline and hydroxyproline in human serum by pre-column high-performance liquid chromatography using 4-(5,6-dimethoxy-2-phthalimidinyl)-2-methoxyphenylsufonyl chloride.

  Journal of chromatography. B, Biomedical sciences and applications 20010615

• Solution structure of the Reps1 EH domain and characterization of its binding to NPF target sequences.

  Biochemistry 20010612

• Structural organization and regulation of the small proline-rich family of cornified envelope precursors suggest a role in adaptive barrier function.

  The Journal of biological chemistry 20010601

• Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling.

  The Journal of biological chemistry 20010601

• Proline residues in two tightly coupled helices of the sulphate transporter, SHST1, are important for sulphate transport.

  The Biochemical journal 20010601

• A partially folded intermediate species of the beta-sheet protein apo-pseudoazurin is trapped during proline-limited folding.

  Protein science : a publication of the Protein Society 20010601

• Solution structure of the PX domain, a target of the SH3 domain.

  Nature structural biology 20010601

• Preorganized secondary structure as an important determinant of fast protein folding.

  Nature structural biology 20010601

• Secretion of non-helical collagenous polypeptides of alpha1(IV) and alpha2(IV) chains upon depletion of ascorbate by cultured human cells.

  Journal of biochemistry 20010601

• Cyclic hydroxamic-acid-containing peptide 31, a potent synthetic histone deacetylase inhibitor with antitumor activity.

  Cancer research 20010601

• Proteolytic processing of a human salivary proline-rich protein precursor by proprotein convertases.

  European journal of biochemistry 20010601

• The group I metabotropic glutamate receptor antagonist S-4-CPG modulates the locomotor response produced by the activation of D1-like, but not D2-like, dopamine receptors in the rat nucleus accumbens.

  The European journal of neuroscience 20010601

• A leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y was not identified in the Japanese population.

  Journal of clinical pharmacy and therapeutics 20010601

• The beta-cell Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) beta3 isoform containing a proline-rich tandem repeat in the association domain can be found in the human genome.

  Diabetologia 20010601

• In vitro comparison of bioabsorbable and non-resorbable membranes in bone regeneration.

  Journal of periodontology 20010601

• The influence of transforming growth factor-beta1 gene polymorphisms on the severity of gingival overgrowth associated with concomitant use of cyclosporin A and a calcium channel blocker.

  Journal of periodontology 20010601

• High constitutive level of NF-kappaB is crucial for viability of adenocarcinoma cells.

  Cell death and differentiation 20010601

• The N-terminal domain of Homer/Vesl is a new class II EVH1 domain.

  Journal of molecular biology 20010525

• Familial parkinsonism with synuclein pathology: clinical and PET studies of A30P mutation carriers.

  Neurology 20010522

• Synthesis of 4-cis-phenyl-L-proline via hydrogenolysis.

  The Journal of organic chemistry 20010518

• Helical stalk segments S4 and S5 of the plasma membrane H+-ATPase from Saccharomyces cerevisiae are optimized to impact catalytic site environment.

  The Journal of biological chemistry 20010511

• Residue Gly1326 of the N-type calcium channel alpha 1B subunit controls reversibility of omega-conotoxin GVIA and MVIIA block.

  The Journal of biological chemistry 20010511

• Binding and regulation of the transcription factor NFAT by the peptidyl prolyl cis-trans isomerase Pin1.

  FEBS letters 20010511

• Convenient method for the determination of arginine and its related compounds in rumen fluid by reversed-phase high-performance liquid chromatography.

  Journal of chromatography. B, Biomedical sciences and applications 20010505

• Pyridoxal phosphate de-activation by pyrroline-5-carboxylic acid. Increased risk of vitamin B6 deficiency and seizures in hyperprolinemia type II.

  The Journal of biological chemistry 20010504

• Aminoethylprolyl (aep) PNA: mixed purine/pyrimidine oligomers and binding orientation preferences for PNA:DNA duplex formation.

  Organic letters 20010503

• Amino acid distributions in integral membrane protein structures.

  Biochimica et biophysica acta 20010502

• NMR conformational analysis of cis and trans proline isomers in the neutrophil chemoattractant, N-acetyl-proline-glycine-proline.

  Biopolymers 20010501

• Towards the molecular mechanism of Na(+)/solute symport in prokaryotes.

  Biochimica et biophysica acta 20010501

• Long-term impairment of anterograde axonal transport along fiber projections originating in the rostral raphe nuclei after treatment with fenfluramine or methylenedioxymethamphetamine.

  Synapse (New York, N.Y.) 20010501

• Evaluation of the role of proline residues flanking the RGD motif of dendroaspin, an inhibitior of platelet aggregation and cell adhesion.

  The Biochemical journal 20010501

• Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL.

  Journal of immunology (Baltimore, Md. : 1950) 20010501

• An extended hydrophobic core induces EF-hand swapping.

  Protein science : a publication of the Protein Society 20010501

• Proline not the only culprit?

  Nature structural biology 20010501

• Nonprolyl cis peptide bonds in unfolded proteins cause complex folding kinetics.

  Nature structural biology 20010501

• Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator--activated receptor-gamma2 gene.

  Diabetes 20010501

• Uptake of cis-4-[18F]fluoro-L-proline in urologic tumors.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20010501

• Effect of sporulation and recovery medium on the heat resistance and amount of injury of spores from spoilage bacilli.

  Journal of applied microbiology 20010501

• 96-well plate-based method for total collagen analysis of cell cultures.

  BioTechniques 20010501

• Complete primary structure of rainbow trout type I collagen consisting of alpha1(I)alpha2(I)alpha3(I) heterotrimers.

  European journal of biochemistry 20010501

• AWD 140-190: a potent anticonvulsant in the amygdala-kindling model of partial epilepsy.

  Epilepsia 20010501

• Pin1 acts catalytically to promote a conformational change in Cdc25.

  Molecular cell 20010501

• Maltodextrins as new chiral selectors in the design of potentiometric, enantioselective membrane electrodes.

  Fresenius' journal of analytical chemistry 20010501

• Conformational changes play a role in regulating the activity of the proline utilization pathway-specific regulator in Saccharomyces cerevisiae.

  Molecular microbiology 20010501

• Effect of solvent on the cis-trans conformational equilibrium of a proline imide bond of short model peptides in solution.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20010501

• Effect of an alpha-blocker (Nicergoline) and of a beta-blocker (Acebutolol) on the in vitro biosynthesis of vascular extracellular matrix.

  Pathologie-biologie 20010501

• Identification and characterization of the major Drosophila melanogaster mating plug protein.

  Insect biochemistry and molecular biology 20010427

• Phosphorylation of protein phosphatase inhibitor-1 by Cdk5.

  The Journal of biological chemistry 20010427

• Proline residues in transmembrane alpha helices affect the folding of bacteriorhodopsin.

  Journal of molecular biology 20010427

• Expression of the platelet receptor GPVI confers signaling via the Fc receptor gamma -chain in response to the snake venom convulxin but not to collagen.

  The Journal of biological chemistry 20010420

• Asymmetric synthesis of alpha-branched primary amines on solid support via novel hydrazine resins.

  Organic letters 20010419

• Structural bases of collagen stabilization induced by proline hydroxylation.

  Biopolymers 20010415

• Binding of CO at the Pro2 side is crucial for the activation of CO-sensing transcriptional activator CooA. (1)H NMR spectroscopic studies.

  The Journal of biological chemistry 20010413

• Selection of ligands by panning of domain libraries displayed on phage lambda reveals new potential partners of synaptojanin 1.

  Journal of molecular biology 20010413

• Studies on the biosynthesis of paraherquamide: concerning the mechanism of the oxidative cyclization of L-isoleucine to beta-methylproline.

  Journal of the American Chemical Society 20010411

• X-ray structure analyses of photosynthetic reaction center variants from Rhodobacter sphaeroides: structural changes induced by point mutations at position L209 modulate electron and proton transfer.

  Biochemistry 20010410

• Sequence-dependent correction of random coil NMR chemical shifts.

  Journal of the American Chemical Society 20010404

• Inhibition of the initial wave of NF-kappaB activity in rat muscle reduces ischemia/reperfusion injury.

  Muscle & nerve 20010401

• Identification of two loci in tomato reveals distinct mechanisms for salt tolerance.

  The Plant cell 20010401

• Effects of synthetic serine protease inhibitors on proliferation and collagen synthesis of human pancreatic periacinar fibroblast-like cells.

  Pancreas 20010401

• Role of EspF in host cell death induced by enteropathogenic Escherichia coli.

  Cellular microbiology 20010401

• Solution structure of the main alpha-amylase inhibitor from amaranth seeds.

  European journal of biochemistry 20010401

• Effects of nitric oxide on reactive oxygen species production and infarction size after brain reperfusion injury.

  Neurosurgery 20010401

• Whole-body kinetics and dosimetry of cis-4-[(18)F]fluoro-L-proline.

  Nuclear medicine and biology 20010401

• Solution structure of an immunoactive peptide fragment of Staphylococcal protein-A.

  Journal of biomolecular structure & dynamics 20010401

• Fullerene-based amino acids and peptides.

  Journal of peptide science : an official publication of the European Peptide Society 20010401

• Effects of amino acid and trace element supplementation on pneumocandin production by Glarea lozoyensis: impact on titer, analogue levels, and the identification of new analogues of pneumocandin B(0).

  Journal of industrial microbiology & biotechnology 20010401

• Phosphorylation-induced structural changes in the amyloid precursor protein cytoplasmic tail detected by NMR.

  Journal of molecular biology 20010330

• Proline suppresses Rubisco activity by dissociating small subunits from holoenzyme.

  Biochemical and biophysical research communications 20010323

• Synthesis of Fmoc-protected trans-4-methylproline.

  The Journal of organic chemistry 20010323

• Factors that control the reactivity of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruzi.

  Biochemistry 20010313

• Modular motif, structural folds and affinity profiles of the PEVK segment of human fetal skeletal muscle titin.

  The Journal of biological chemistry 20010309

• A genetic investigation of the essential role of glutathione: mutations in the proline biosynthesis pathway are the only suppressors of glutathione auxotrophy in yeast.

  The Journal of biological chemistry 20010309

• Sequence requirements for the N-methyl-D-aspartate receptor antagonist activity of conantokin-R.

  The Journal of biological chemistry 20010309

• Masked oxo sulfinimines (N-sulfinyl imines) in the asymmetric synthesis of proline and pipecolic acid derivatives.

  Organic letters 20010308

• Enhanced triple helix stability of collagen peptides with 4R-aminoprolyl (Amp) residues: relative roles of electrostatic and hydrogen bonding effects.

  Journal of the American Chemical Society 20010307

• Difference in molecular structure of rod and cone visual pigments studied by Fourier transform infrared spectroscopy.

  Biochemistry 20010306

• Arginine and ornithine kinetics in severely burned patients: increased rate of arginine disposal.

  American journal of physiology. Endocrinology and metabolism 20010301

• Chemical C-terminal protein sequence analysis: improved sensitivity, length of degradation, proline passage, and combination with edman degradation.

  Analytical biochemistry 20010301

• Purification, crystallization and preliminary crystallographic analysis of the periplasmic binding protein ProX from Escherichia coli.

  Acta crystallographica. Section D, Biological crystallography 20010301

• A prion-like shift between two conformational forms of a recombinant thyrotropin receptor A-subunit module: purification and stabilization using chemical chaperones of the form reactive with Graves' autoantibodies.

  The Journal of clinical endocrinology and metabolism 20010301

• Differences in proliferation of the hematopoietic cell line TF-1 and cytokine production by peripheral blood leukocytes induced by 2 naturally occurring forms of human IL-3.

  The Journal of allergy and clinical immunology 20010301

• A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidaemia in obesity.

  European journal of endocrinology 20010301

• Is the P25L a 'real' VHL mutation?

  Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology 20010301

• Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen species.

  Cancer research 20010301

• Density functional computations of proton affinity and gas-phase basicity of proline.

  Journal of mass spectrometry : JMS 20010301

• Characterization of natural 'cooling' compounds formed from glucose and l-proline in dark malt by application of taste dilution analysis.

  Journal of agricultural and food chemistry 20010301

• The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif.

  Oncogene 20010301

• The product of ORF III in cauliflower mosaic virus interacts with the viral coat protein through its C-terminal proline rich domain.

  Virus genes 20010301

• Basic proline-rich proteins: multifunctional defence molecules?

  Oral diseases 20010301

• Parotid salivary basic proline-rich proteins inhibit HIV-I infectivity.

  Oral diseases 20010301

• Molecular cloning, physical mapping, and expression analysis of a novel gene, BCL2L12, encoding a proline-rich protein with a highly conserved BH2 domain of the Bcl-2 family.

  Genomics 20010301

• No leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y in Japanese population or Japanese with alcoholism.

  Psychiatric genetics 20010301

• Wiskott-Aldrich syndrome (role of WASP).

  Journal of medical and dental sciences 20010301

• Transforming growth factor-beta(1) stimulates L-arginine transport and metabolism in vascular smooth muscle cells: role in polyamine and collagen synthesis.

  Circulation 20010227

• Solution structure of Grb2 reveals extensive flexibility necessary for target recognition.

  Journal of molecular biology 20010223

• Different susceptibility to oxidation of proline and arginine residues of apolipoprotein B-100 among subspecies of low density lipoproteins.

  FEBS letters 20010223

• Proline-catalyzed asymmetric aldol reactions between ketones and alpha-unsubstituted aldehydes.

  Organic letters 20010222

• Identification of human CYP2C19 residues that confer S-mephenytoin 4'-hydroxylation activity to CYP2C9.

  Biochemistry 20010220

• The structural basis for the perturbed pKa of the catalytic base in 4-oxalocrotonate tautomerase: kinetic and structural effects of mutations of Phe-50.

  Biochemistry 20010220

• Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.

  The Journal of biological chemistry 20010216

• The mGlu(2/3) agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate, is anti- and proconvulsant in DBA/2 mice.

  Neuroscience letters 20010216

• Effects of glycyrrhetinic acid on collagen metabolism of hepatic stellate cells at different stages of liver fibrosis in rats.

  World journal of gastroenterology 20010215

• Involvement of glycine 141 in substrate activation by enoyl-CoA hydratase.

  Biochemistry 20010213

• The adaptive regulation of amino acid transport system A is associated to changes in ATA2 expression.

  FEBS letters 20010209

• The role of a proline-induced broken-helix motif in alpha-helix 2 of Bacillus thuringiensis delta-endotoxins.

  FEBS letters 20010209

• Practical and efficient synthesis of orthogonally protected constrained 4-guanidinoprolines.

  The Journal of organic chemistry 20010209

• A polymer-supported proline-based diamine catalyst for the kinetic resolution of racemic secondary alcohols.

  The Journal of organic chemistry 20010209

• DNA recognition by the methyl-CpG binding domain of MeCP2.

  The Journal of biological chemistry 20010202

• Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity.

  The Journal of biological chemistry 20010202

• Glycogen synthase kinase-3 inhibits the DNA binding activity of NFATc.

  The Journal of biological chemistry 20010202

• A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling.

  The Journal of biological chemistry 20010202

• The scFv fragment of the antibody hu4D5-8: evidence for early premature domain interaction in refolding.

  Journal of molecular biology 20010202

• Disulfide bridge reorganization induced by proline mutations in maurotoxin.

  FEBS letters 20010202

• Effect of the peroxisome proliferator-activated receptor-gamma 2 pro(12)ala variant on obesity, glucose homeostasis, and blood pressure in members of familial type 2 diabetic kindreds.

  The Journal of clinical endocrinology and metabolism 20010201

• Database analysis of O-glycosylation sites in proteins.

  Biophysical journal 20010201

• Hypoxia/reoxygenation promotes myocardial angiogenesis via an NF kappa B-dependent mechanism in a rat model of chronic myocardial infarction.

  Journal of molecular and cellular cardiology 20010201

• Microsomal p450s use specific proline-rich sequences for efficient folding, but not for maintenance of the folded structure.

  Journal of biochemistry 20010201

• Importance of a proline-rich sequence in the amino-terminal region for correct folding of mitochondrial and soluble microbial p450s.

  Journal of biochemistry 20010201

• Mutation at codon 130 in hepatitis B virus (HBV) core region increases markedly during acute exacerbation of hepatitis in chronic HBV carriers.

  Journal of gastroenterology 20010201

• p38 Map kinase regulates vascular smooth muscle cell collagen synthesis by angiotensin II in SHR but not in WKY.

  Hypertension (Dallas, Tex. : 1979) 20010201

• Long-term antioxidant administration attenuates mineralocorticoid hypertension and renal inflammatory response.

  Hypertension (Dallas, Tex. : 1979) 20010201

• NMR and simulated annealing investigations of bradykinin in presence of polyphenols.

  Journal of biomolecular structure & dynamics 20010201

• Cycloheximide resistance conferred by novel mutations in ribosomal protein L41 of Chlamydomonas reinhardtii.

  Molecular & general genetics : MGG 20010201

• Improving water stress tolerance of the biocontrol yeast Candida sake grown in molasses-based media by physiological manipulation.

  Canadian journal of microbiology 20010201

• Discrimination between orange juice and pulp wash by (1)H Nuclear Magnetic Resonance spectroscopy: identification of marker compounds.

  Journal of agricultural and food chemistry 20010201

• Antibodies recognizing CD24 LAP epitope on human T cells enhance CD28 and IL-2 T cell proliferation.

  Journal of leukocyte biology 20010201

• Influence of N-terminal residue stereochemistry on the prolyl amide geometry and the conformation of 5-tert-butylproline type VI beta-turn mimics.

  Journal of peptide science : an official publication of the European Peptide Society 20010201

• S-nitrosoglutathione inhibits TNF-alpha-induced NFkappaB activation in neutrophils.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010201

• Molecular cloning and functional characterization of two kinds of betaine-aldehyde dehydrogenase in betaine-accumulating mangrove Avicennia marina (Forsk.) Vierh.

  Plant molecular biology 20010201

• New Zealand Maori family with the pro250arg fibroblast growth factor receptor 3 mutation associated with craniosynostosis.

  Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 20010201

• [Effects of copper mine tailings on growth and development and physiological function of wheat].

  Ying yong sheng tai xue bao = The journal of applied ecology 20010201

• PRH represses transcription in hematopoietic cells by at least two independent mechanisms.

  The Journal of biological chemistry 20010126

• Absence of association between HPV DNA, TP53 codon 72 polymorphism, and risk of oesophageal cancer in a high-risk area of China.

  Cancer letters 20010126

• Intermolecular interactions between the SH3 domain and the proline-rich TH region of Bruton's tyrosine kinase.

  FEBS letters 20010126

• Poly-L-proline type II peptide mimics based on the 3-azabicyclo[3.1.0]hexane system.

  The Journal of organic chemistry 20010126

• p13(SUC1) and the WW domain of PIN1 bind to the same phosphothreonine-proline epitope.

  The Journal of biological chemistry 20010112

• Antioxidant therapy attenuates JNK activation and apoptosis in the remote noninfarcted myocardium after large myocardial infarction.

  Biochemical and biophysical research communications 20010112

• Three-dimensional structure topology of the calreticulin P-domain based on NMR assignment.

  FEBS letters 20010112

• Methanococcus jannaschii prolyl-cysteinyl-tRNA synthetase possesses overlapping amino acid binding sites.

  Biochemistry 20010109

• The mechanism for anthracycline-induced inhibition of collagen biosynthesis.

  European journal of pharmacology 20010105

• NMR studies of adrenocorticotropin hormone peptides in sodium dodecylsulfate and dodecylphosphocholine micelles: proline isomerism and interactions of the peptides with micelles.

  Biopolymers 20010101

• Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells.

  American journal of physiology. Endocrinology and metabolism 20010101

• Intestinal apical amino acid absorption during development of the pig.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010101

• The destabilization of human GCAP1 by a proline to leucine mutation might cause cone-rod dystrophy.

  Human molecular genetics 20010101

• Prevalence of mutations causing retinitis pigmentosa and other inherited retinopathies.

  Human mutation 20010101

• Novel mutations in the GALK1 gene in patients with galactokinase deficiency.

  Human mutation 20010101

• T>C transition in codon 72 (TCG-->CCG), S72P, a putative hotspot in PMP22.

  Human mutation 20010101

• Cell motility: proline-rich proteins promote protrusions.

  Trends in cell biology 20010101

• Mutated-gamma-actin restores growth to a yeast amino acid transport defective mutant.

  Journal of cellular physiology 20010101

• Analysis of collagenase-cleavage of type II collagen using a neoepitope ELISA.

  Journal of immunological methods 20010101

• Proline transport in MDCK cells expressing a mutant regulatory subunit of cAMP-dependent protein kinase.

  Molecular genetics and metabolism 20010101

• Effects of L-proline on phase I and phase II xenobiotic biotransformation capacities of rat and human hepatocytes in long-term collagen gel cultures.

  Alternatives to laboratory animals : ATLA 20010101

• Nonproteolytic cleavage of aspartyl proline bonds in the cellulosomal scaffoldin subunit from Clostridium thermocellum.

  Applied biochemistry and biotechnology 20010101

• The effect of dynamic compression on the response of articular cartilage to insulin-like growth factor-I.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20010101

• Characterization of the amino acid transport of new immortalized choroid plexus epithelial cell lines: a novel in vitro system for investigating transport functions at the blood-cerebrospinal fluid barrier.

  Pharmaceutical research 20010101

• [Oxidation-reduction and production of molecular hydrogen by Escherichia coli in the hyperosmotic medium].

  Biofizika 20010101

• Perichondrium-wrapped collagenous matrices to induce chondroneogenesis: an in vitro study.

  Archives of facial plastic surgery 20010101

• Estimation of proton affinity of proline and tryptophan under electrospray ionization conditions using the extended kinetic method.

  Rapid communications in mass spectrometry : RCM 20010101

• Release behavior of ketoprofen from poly(acryloyl-L-proline methyl ester) gels having different crosslinked networks.

  Pharmaceutical development and technology 20010101

• Site-directed mutagenesis of proline-285 to leucine in Cephalosporium acremonium isopenicillin-N-synthase affects catalysis and increases soluble expression at higher temperatures.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101

• Solid-phase library synthesis of alkoxyprolines.

  Journal of combinatorial chemistry 20010101

• The effect of heat shock on amino acid transport and cell volume in 3T3 cells.

  Amino acids 20010101

• [Hyperprolinemia].

  Ryoikibetsu shokogun shirizu 20010101

• Peripherin/RDS gene mutation (Pro210Leu) and polymorphisms in Japanese patients with retinal dystrophies.

  Japanese journal of ophthalmology 20010101

• Morphohistobiochemical characteristics of embryogenic and nonembryogenic callus cultures of sweet potato (Ipomoea batatas L.).

  Cytobios 20010101

• Synthesis and evaluation of prolyl carbamate nucleic acids (PrCNA).

  Nucleosides, nucleotides & nucleic acids 20010101

• Nitric oxide and vasospasm.

  Acta neurochirurgica. Supplement 20010101

• Application of L-threonine aldolase-catalyzed reaction to the preparation of protected 3R,5R-dihydroxy-L-homoproline as a mimetic of idulonic acid.

  Chirality 20010101

• Survivability of biomolecules during extraterrestrial delivery: new results on pyrolysis of amino acids and poly-amino acids.

  Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20010101

• Substrate recognition by proline permease in Salmonella.

  Amino acids 20010101

• Effect of proline on the production of singlet oxygen.

  Amino acids 20010101

• [The factors of improving rice transformation efficiency].

  Yi chuan xue bao = Acta genetica Sinica 20010101

• Proline alleviates heavy metal stress in Scenedesmus armatus.

  Folia microbiologica 20010101

• Relation between the flexibility of the WPD loop and the activity of the catalytic domain of protein tyrosine phosphatase SHP-1.

  Journal of cellular biochemistry 20010101

• Atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry of sulfonic acid derivatized tryptic peptides.

  Rapid communications in mass spectrometry : RCM 20010101

• A new mutation of the arginine vasopressin-neurophysin II gene in a family with autosomal dominant neurohypophyseal diabetes insipidus.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20010101

• Methods and strategies of peptide ligation.

  Biopolymers 20010101

• L-proline analogues of anthraquinone-2-carboxylic acid: cytotoxic activity in breast cancer MCF-7 cells and inhibitory activity against topoisomerase I and II.

  Polish journal of pharmacology 20010101

• Cholesterol-induced upregulation of angiotensin II and its effects on monocyte-endothelial interaction and superoxide production.

  Vascular medicine (London, England) 20010101

• Determination of Ascochyta caulina phytotoxins by high-performance anion exchange chromatography and pulsed amperometric detection.

  Phytochemical analysis : PCA 20010101

• Cytotoxicity activity of L-proline analogues of anthraquinone-2-carboxylic acid in breast cancer MCF-7 cells.

  Folia histochemica et cytobiologica 20010101

• Proline analogue of melphalan as a prolidase-convertible pro-drug in breast cancer MCF-7 cells.

  Folia histochemica et cytobiologica 20010101

• Regulation of L-arginine transport and metabolism in vascular smooth muscle cells.

  Cell biochemistry and biophysics 20010101

• Alterations of collagen matrix in weight-bearing bones during skeletal unloading.

  Connective tissue research 20010101

• Antibacterial peptides of the moth Galleria mellonella.

  Acta biochimica Polonica 20010101

• [Fibrin-depolymerization activity and the antiplatelet effect of small cyclic and linear proline-containing peptides].

  Izvestiia Akademii nauk. Seriia biologicheskaia 20010101

• Effect of the two conserved prolines of human growth inhibitory factor (metallothionein-3) on its biological activity and structure fluctuation: comparison with a mutant protein.

  Biochemistry 20001128

• Use of proline bioisosteres in potential HIV protease inhibitors: phenylalanine-2-thiophenoxy-3-pyrrolidinone: synthesis and anti-HIV evaluation.

  Bioorganic & medicinal chemistry letters 20000904

• Computer-assisted design, synthesis and biological evaluation of novel pyrrolyl heteroaryl sulfones targeted at HIV-1 reverse transcriptase as non-nucleoside inhibitors.

  Bioorganic & medicinal chemistry 20000901

• GABA uptake inhibitors. Design, molecular pharmacology and therapeutic aspects.

  Current pharmaceutical design 20000801

• Total synthesis and antifungal evaluation of cyclic aminohexapeptides.

  Bioorganic & medicinal chemistry 20000701

• Probing the role of a conserved M1 proline residue in 5-hydroxytryptamine(3) receptor gating.

  Molecular pharmacology 20000601

• Estradiol inhibits smooth muscle cell growth in part by activating the cAMP-adenosine pathway.

  Hypertension (Dallas, Tex. : 1979) 20000101

• A new point mutation (P157S) in the reverse transcriptase of human immunodeficiency virus type 1 confers low-level resistance to (-)-beta-2',3'-dideoxy-3'-thiacytidine.

  Antimicrobial agents and chemotherapy 19990801

• Influence of fulvic acid on the collagen secretion of bovine chondrocytes in vitro.

  Cell and tissue research 19990701

• Induction of stromelysin gene expression by tumor necrosis factor alpha is inhibited by dexamethasone, salicylate, and N-acetylcysteine in synovial fibroblasts.

  The Journal of pharmacology and experimental therapeutics 19990601

• Pyrimidine thioethers: a novel class of HIV-1 reverse transcriptase inhibitors with activity against BHAP-resistant HIV.

  Journal of medicinal chemistry 19980924

• Antibody catalysis of peptidyl-prolyl cis-trans isomerization in the folding of RNase T1.

  Proceedings of the National Academy of Sciences of the United States of America 19980623

• A proline-to-histidine substitution at position 225 of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) sensitizes HIV-1 RT to BHAP U-90152.

  The Journal of general virology 19980601

• Antifungal activities of rapamycin and its derivatives, prolylrapamycin, 32-desmethylrapamycin, and 32-desmethoxyrapamycin.

  The Journal of antibiotics 19980501

• Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B.

  The Journal of clinical investigation 19980301

• Syntheses of new modified Phe-Pro peptides. Use of proline replacements in potential HIV inhibitors.

  Bioorganic & medicinal chemistry letters 19980203

• Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism.

  Science (New York, N.Y.) 19971212

• MTC28, a novel 28-kilodalton proline-rich secreted antigen specific for the Mycobacterium tuberculosis complex.

  Infection and immunity 19971201

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  Biochemistry 19971111

• Characteristics of the Pro225His mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase that appears under selective pressure of dose-escalating quinoxaline treatment of HIV-1.

  Journal of virology 19971101

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  FEBS letters 19970901

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  Journal of the American Society of Nephrology : JASN 19970401

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  The Journal of biological chemistry 19970307

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  British journal of pharmacology 19970301

• Distinct sequences of AKH/RPCH family members in beetle (Scarabaeus-species) corpus cardiacum contain three aromatic amino acid residues.

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• Hyperprolinaemia caused by novel members of the adipokinetic hormone/red pigment-concentrating hormone family of peptides isolated from corpora cardiaca of onitine beetles.

  The Biochemical journal 19970101

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  Folding & design 19970101

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  Bioscience, biotechnology, and biochemistry 19960801

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  FEBS letters 19960603

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  FEBS letters 19950213

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  Peptides 19950101

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  Journal of molecular biology 19941104

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  Bioorganic & medicinal chemistry 19941001

• Turn induction by N-aminoproline. Comparison of the Gly-Pro-Gly and Gly psi [CO-NH-N]Pro-Gly sequences.

  International journal of peptide and protein research 19941001

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  Biopolymers 19940201

• Specificity for various imino-acid-residues of a proline-specific dipeptidylcarboxypeptidase from a Streptomyces species.

  Biochimica et biophysica acta 19930305

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  Proteins 19930301

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  Epilepsy research 19930201

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  The Biochemical journal 19930201

• The presence of free D-serine, D-alanine and D-proline in human plasma.

  Experientia 19921015

• Pharmacology of a phosphorus-containing novel angiotensin converting enzyme inhibitor, SQ 29 852 in anesthetized dogs.

  Journal of pharmacobio-dynamics 19911201

• Synthesis, conformational properties, and antibody recognition of peptides containing beta-turn mimetics based on alpha-alkylproline derivatives.

  Journal of medicinal chemistry 19910601

• Microbore liquid chromatography coupled to a flow fast atom bombardment probe for the on-line detection of the Tyr-Pro cleavage of a nonapeptide by recombinant HIV-1 protease.

  Journal of chromatography 19910102

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  Biomedica biochimica acta 19910101

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  Kidney international 19901201

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  Journal of cardiovascular pharmacology 19891101

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  FEBS letters 19881010

• Synergistic binding of ligands to angiotensin-converting enzyme.

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  International journal of peptide and protein research 19880201

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  The Journal of biological chemistry 19870825

• The effect of captopril on urinary protein excretion in puromycin aminonucleoside nephrosis in rats.

  Pediatric research 19850801

• Cytochemical localization and biochemical evaluation of a lysosomal serine protease in lung: dipeptidyl peptidase II in the normal rat.

  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 19850701

• Mammalian ribonucleases. The absence of a glycosylated Asn-Pro-Thr sequence in horse ribonuclease and the presence of tryptophan at position 39 in horse and dromedary ribonuclease.

  FEBS letters 19850603

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  American heart journal 19850601

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  Journal of hypertension 19850401

• Disappearance of captopril-induced taste disturbance after substitution with angiotensin-converting-enzyme inhibitor HOE 498.

  Lancet (London, England) 19850302

• Blood pressure and metabolic responses to hydrochlorothiazide, captopril, and the combination in black and white mild-to-moderate hypertensive patients.

  Journal of cardiovascular pharmacology 19850101

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  Journal of cardiovascular pharmacology 19850101

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  The American journal of physiology 19841201

• Angiotensin II levels, hemodynamics, and sympathoadrenal function after low-dose captopril in heart failure.

  The American journal of medicine 19841101

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  Klinische Wochenschrift 19840102

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  Scandinavian journal of urology and nephrology. Supplementum 19840101

• Effects of prolonged administration of D-penicillamine or captopril in various strains of rats. Brown Norway rats treated with D-penicillamine develop autoantibodies, circulating immune complexes, and disseminated intravascular coagulation.

  Clinical immunology and immunopathology 19840101

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  Pathologica 19840101

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  Journal of biochemistry 19831101

• Left ventricular mass and function before and after antihypertensive treatment.

  Journal of hypertension 19831001

• Hemodynamic responses to combined therapy with captopril and hydralazine in patients with severe heart failure.

  Journal of the American College of Cardiology 19830801

• Double-blind comparison between propranolol and bendroflumethiazide in captopril-treated resistant hypertensive patients.

  American heart journal 19830801

• Autonomic and baroreflex function after captopril in hypertension.

  American heart journal 19830601

• Structural requirements of N-glycosylation of proteins. Studies with proline peptides as conformational probes.

  The Biochemical journal 19830201

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  Hypertension (Dallas, Tex. : 1979) 19830101

• Effect of bendrofluazide on the renin-angiotensin-aldosterone system and prostaglandins in captopril-resistant hypertensive patients.

  Clinical and experimental hypertension. Part A, Theory and practice 19830101

• Effect of captopril and propranolol, alone and in combination, on the responses to isometric and dynamic exercise in normotensive and hypertensive men.

  Pharmacotherapy 19830101

• Hemodynamic and humoral interactions between captopril and nifedipine.

  Hypertension (Dallas, Tex. : 1979) 19830101

• Captopril or atenolol in essential hypertension.

  Acta medica Scandinavica. Supplementum 19830101

• Evaluation of the chronotropic property of captopril in hypertensive patients.

  American heart journal 19821201

• The renin-angiotensin system in aminoglycoside-induced acute renal failure.

  The Journal of pharmacology and experimental therapeutics 19820201

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  Clinical and experimental hypertension. Part A, Theory and practice 19820101

• Captopril and atenolol combined with hydrochlorothiazide in essential hypertension.

  British journal of clinical pharmacology 19820101

• Acute hypotensive effect of captopril in man modified by prostaglandin synthesis inhibition.

  British journal of clinical pharmacology 19820101

• Effects of prostaglandins inhibition on changes in active and inactive renin induced by antihypertensive drugs.

  Clinical and experimental hypertension. Part A, Theory and practice 19820101

• The hypotensive effect of propranolol in captopril-treated patients does not involve the plasma renin--angiotensin--aldosterone system.

  Clinical science (London, England : 1979) 19811201

• Potentiation of the morphine-induced respiratory rate depression by captopril.

  European journal of pharmacology 19810326

• Effect of captopril on pre-existing and aminonucleoside-induced proteinuria in spontaneously hypertensive rats.

  Research communications in chemical pathology and pharmacology 19810301

• Comparison of antihypertensive effects of captopril and propranolol in essential hypertension.

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• Changes in prolyl endopeptidase during maturation of rat brain and hydrolysis of substance P by the purified enzyme.

  Journal of neurochemistry 19800901

• Neurological dysfunction in two patients receiving captopril and cimetidine.

  Lancet (London, England) 19800705

• The amino acid sequence of a salivary proline-rich peptide, P-C, and its relation to a salivary proline-rich phosphoprotein, protein C.

  Journal of biochemistry 19800401

• Comparison of the acute and chronic hemodynamic effects of captopril and guanethidine in spontaneously hypertensive rats.

  Clinical and experimental hypertension 19800201

• First dose effect of the oral angiotensin converting enzyme inhibitor captopril.

  Archives internationales de pharmacodynamie et de therapie 19800101

• Captopril in the treatment of clinical hypertension and cardiac failure.

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• Reversible renal failure during treatment with captopril.

  British medical journal 19790908

• An incipient 3(10) helix in Piv-Pro-Pro-Ala-NHMe as a model for peptide folding.

  Nature 19790906

• Effects of chronic treatment with captopril (SQ 14,225), an orally active inhibitor of angiotensin I-converting enzyme, in spontaneously hypertensive rats.

  Japanese journal of pharmacology 19790401

• Nuclear-magnetic-resonance study of aggregations and conformations of melanostatin and related peptides.

  European journal of biochemistry 19780901

• Selenaproline and protein synthesis.

  Biochimica et biophysica acta 19770920

• C-Terminal peptidyl-L-proline hydrolase activity of Aspergillus acid carboxypeptidase.

  Journal of biochemistry 19770601

• Post-proline cleaving enzyme. Purification of this endopeptidase by affinity chromatography.

  The Journal of biological chemistry 19761210

• The pH dependence of the conformation of angiotensin peptides by nuclear magnetic resonance: cis-trans isomerism of proline 7.

  Biochemistry 19760601

• Intestinal absorption of amino acids in rats infected with Nematospiroides dubius.

  Comparative biochemistry and physiology. A, Comparative physiology 19751201

• Prolyl hydroxylase and collagen metabolism after experimental mycardial infarction.

  The American journal of physiology 19750101

• Conformational interconversions of the cyclic hexapeptide cyclo(Pro-Gly) 3 .

  Proceedings of the National Academy of Sciences of the United States of America 19720701