3539-97-7 | (S)-1,1,1-Trifluoro-2-propanol

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$5.00	$4.00
250mg	98%	in stock	$6.00	$5.00
10g	98%	in stock	$22.00	$16.00
25g	98%	in stock	$53.00	$38.00

Description

• Catalog Number: AF73888
• Chemical Name: (S)-1,1,1-Trifluoro-2-propanol
• CAS Number: 3539-97-7
• Molecular Formula: C3H5F3O
• Molecular Weight: 114.0664096
• MDL Number: MFCD06797331
• SMILES: C[C@@H](C(F)(F)F)O

Computed Properties

• Complexity: 57.7
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 7
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• XLogP3: 0.7

Upstream Synthesis Route

(S)-1,1,1-Trifluoro-2-propanol, often referred to simply as TFIP, is a valuable building block in chemical synthesis due to its unique properties and reactivity. This compound is commonly used as a chiral auxiliary in asymmetric synthesis, where its distinct three-carbon structure and trifluoromethyl group play a crucial role in controlling stereochemistry.One key application of (S)-1,1,1-Trifluoro-2-propanol is in the preparation of various pharmaceutical intermediates and fine chemicals. Its chirality can induce asymmetry in reactions, leading to the formation of enantiomerically enriched products. This is particularly important in the synthesis of drugs and biologically active compounds, where the specific spatial arrangement of molecules can significantly impact their interactions with biological targets.Furthermore, TFIP can serve as a precursor for the synthesis of fluorinated organic compounds, which are widely used in medicinal chemistry, materials science, and agrochemicals. The trifluoromethyl group in (S)-1,1,1-Trifluoro-2-propanol can be functionalized to introduce fluorine atoms into organic molecules, enhancing their chemical and physical properties.Overall, the versatility and utility of (S)-1,1,1-Trifluoro-2-propanol make it a valuable tool in the hands of synthetic chemists for designing and synthesizing complex molecules with high efficiency and selectivity.