35457-80-8 | Midecamycin

Packsize	Purity	Availability	Price	Discounted Price
50mg	95%	in stock	$15.00	$10.00
100mg	95%	in stock	$18.00	$12.00
250mg	95%	in stock	$28.00	$19.00
1g	95%	in stock	$45.00	$32.00
5g	95%	in stock	$137.00	$96.00
25g	95%	in stock	$421.00	$295.00

Description

• Catalog Number: AD41807
• Chemical Name: Midecamycin
• CAS Number: 35457-80-8
• Molecular Formula: C41H67NO15
• Molecular Weight: 813.9684
• MDL Number: MFCD00865000
• SMILES: O=CC[C@@H]1C[C@H](C)[C@H](O)C=CC=CC[C@@H](OC(=O)C[C@H]([C@H]([C@@H]1O[C@H]1O[C@@H](C)[C@@H]([C@H]([C@@H]1O)N(C)C)O[C@H]1O[C@H](C)[C@H]([C@@](C1)(C)O)OC(=O)CC)OC)OC(=O)CC)C

Computed Properties

• Complexity: 1360
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 16
• Defined Bond Stereocenter Count: 2
• Heavy Atom Count: 57
• Hydrogen Bond Acceptor Count: 16
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 14
• XLogP3: 2.6

Literature

• A Good War? Exploring British veterans' moral evaluation of deployment.

  Journal of anxiety disorders 20110101

• [Experimental study of cardioprotective and endothelioprotective action of macrolides and azalides].

  Eksperimental'naia i klinicheskaia farmakologiia 20090101

• [Acylation specificity of midecamycin 3-O-acyltransferase within Streptomyces spiramyceticus F21].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20081201

• Novel 16-membered macrolides modified at C-12 and C-13 positions of midecamycin A1 and miokamycin. Part 1: Synthesis and evaluation of 12,13-carbamate and 12-arylalkylamino-13-hydroxy analogues.

  Bioorganic & medicinal chemistry 20080401

• Cloning and characterization of genes encoded in dTDP-D-mycaminose biosynthetic pathway from a midecamycin-producing strain, Streptomyces mycarofaciens.

  Acta biochimica et biophysica Sinica 20070301

• Application of liquid chromatography-ion trap mass spectrometry to the characterization of the 16-membered ring macrolide josamycin propionate.

  Journal of mass spectrometry : JMS 20040401

• Effects of the macrolide antibiotic, midecamycin, on Staphylococcus aureus product-induced Th2 cytokine response in patients with atopic dermatitis.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20040301

• Antibiotic use profile at paediatric clinics in two transitional countries.

  Pharmacoepidemiology and drug safety 20040301

• Determination of midecamycin by capillary zone electrophoresis with electrochemical detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030115

• [Drug sensitivity of Ureaplasma urealyticum, persisting in patients with chronic inflammatory diseases of the urogenital tract].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20030101

• Potential cholestatic activity of various therapeutic agents assessed by bile canalicular membrane vesicles isolated from rats and humans.

  Drug metabolism and pharmacokinetics 20030101

• [Macrolide consumption according to geographic areas in the province of Valladolid].

  Enfermedades infecciosas y microbiologia clinica 20021201

• Quantitative comparison of the cytocidal effect of seven macrolide antibiotics on human periodontal ligament fibroblasts.

  Journal of periodontal research 20020801

• Modulatory effect of macrolide antibiotics on the Th1- and Th2-type cytokine production.

  International journal of antimicrobial agents 20020101

• In vitro activity of midecamycin diacetate, a 16-membered macrolide, against Streptococcus pyogenes isolated in France, 1995-1999.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20010701

• In vitro activity of midecamycin diacetate against Mycoplasma pneumoniae and Chlamydia pneumoniae.

  The Journal of antimicrobial chemotherapy 20010201

• [Midekamycin and midekamycin acetate--macrolide antibiotics for treatment of respiratory infections].

  Terapevticheskii arkhiv 20010101