35661-60-0 | Fmoc-leu-oh

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$6.00	$4.00
10g	98%	in stock	$7.00	$5.00
25g	98%	in stock	$13.00	$9.00
100g	98%	in stock	$44.00	$31.00
500g	98%	in stock	$164.00	$115.00

Description

• Catalog Number: AI48784
• Chemical Name: Fmoc-leu-oh
• CAS Number: 35661-60-0
• Molecular Formula: C21H23NO4
• Molecular Weight: 353.4116
• MDL Number: MFCD10567377
• SMILES: CC(C[C@@H](C(=O)O)NC(=O)OCC1c2ccccc2c2c1cccc2)C

Computed Properties

• Complexity: 484
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 26
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 7
• XLogP3: 4.4

Literature

• Study on cow ghee versus soybean oil on 7,12-dimethylbenz(a)-anthracene induced mammary carcinogenesis & expression of cyclooxygenase-2 & peroxisome proliferators activated receptor-γ in rats.

  The Indian journal of medical research 20110501

• Comparative dynamics of leucine methyl groups in FMOC-leucine and in a protein hydrophobic core probed by solid-state deuteron nuclear magnetic resonance over 7-324 K temperature range.

  The journal of physical chemistry. B 20101209

• The 20S proteasome splicing activity discovered by SpliceMet.

  PLoS computational biology 20100601

• Hydrogelation and self-assembly of Fmoc-tripeptides: unexpected influence of sequence on self-assembled fibril structure, and hydrogel modulus and anisotropy.

  Langmuir : the ACS journal of surfaces and colloids 20100406

• Suppression of tumor formation by a cyclooxygenase-2 inhibitor and a peroxisome proliferator-activated receptor gamma agonist in an in vivo mouse model of spontaneous breast cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080801

• The PPARgamma agonist FMOC-L-leucine protects both mature and immature brain.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080101

• 'Striking the Right Balance' in Targeting PPARgamma in the Metabolic Syndrome: Novel Insights from Human Genetic Studies.

  PPAR research 20070101

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Characterization of compound mechanisms and secondary activities by BioMAP analysis.

  Journal of pharmacological and toxicological methods 20060101

• Self-assembly of small molecules affords multifunctional supramolecular hydrogels for topically treating simulated uranium wounds.

  Chemical communications (Cambridge, England) 20050921

• Inhibition of rat mammary gland carcinogenesis by simultaneous targeting of cyclooxygenase-2 and peroxisome proliferator-activated receptor gamma.

  Cancer research 20040201

• PPAR-gamma: a thrifty transcription factor.

  Nuclear receptor signaling 20030101

• Effect of NPC-15199 on Ca2+ levels in renal tubular cells.

  The Chinese journal of physiology 20020930

• PPARgamma, an X-ceptor for Xs.

  Annals of the New York Academy of Sciences 20020601