3701-01-7 | Benzene-1,3-disulfonamide

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$188.00	$132.00
200mg	>98.0%(HPLC)(N)	in stock	$200.00	$140.00
1g	>98.0%(HPLC)(N)	in stock	$598.00	$419.00

Description

• Catalog Number: AB45587
• Chemical Name: Benzene-1,3-disulfonamide
• CAS Number: 3701-01-7
• Molecular Formula: C6H8N2O4S2
• Molecular Weight: 236.2687
• MDL Number: MFCD00025383
• SMILES: NS(=O)(=O)c1cccc(c1)S(=O)(=O)N

Computed Properties

• Complexity: 351
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: -0.6

Literature

• Carbonic anhydrase inhibitors: purification and inhibition studies of pigeon (Columba livia var. domestica) red blood cell carbonic anhydrase with sulfonamides.

  Journal of enzyme inhibition and medicinal chemistry 20111001

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations.

  Bioorganic & medicinal chemistry 20100715

• Carbonic anhydrase inhibitors: inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides--solution and crystallographic studies.

  Bioorganic & medicinal chemistry letters 20070801

• Carbonic anhydrase inhibitors: inhibition of the human transmembrane isozyme XIV with a library of aromatic/heterocyclic sulfonamides.

  Bioorganic & medicinal chemistry 20051115

• Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozymes IX and XII with a library of aromatic and heteroaromatic sulfonamides.

  Bioorganic & medicinal chemistry letters 20051101

• Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.

  Bioorganic & medicinal chemistry letters 20050901

• Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides.

  Bioorganic & medicinal chemistry letters 20041220

• Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.

  Bioorganic & medicinal chemistry letters 20030324