372-75-8 | L-Citrulline

Packsize	Purity	Availability	Price	Discounted Price
100g	98%	in stock	$16.00	$11.00
500g	98%	in stock	$58.00	$40.00

Description

• Catalog Number: AB49586
• Chemical Name: L-Citrulline
• CAS Number: 372-75-8
• Molecular Formula: C6H13N3O3
• Molecular Weight: 175.1857
• MDL Number: MFCD00064397
• SMILES: NC(=O)NCCC[C@@H](C(=O)O)N

Computed Properties

• Complexity: 171
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 5
• XLogP3: -4.3

Upstream Synthesis Route

N5-(Aminocarbonyl)-L-ornithine, a versatile compound in chemical synthesis, serves as a crucial building block in the production of various pharmaceuticals and bioactive molecules. With its unique molecular structure, this compound plays a pivotal role in the creation of peptide sequences and complex organic compounds. Additionally, N5-(Aminocarbonyl)-L-ornithine is widely utilized as a key intermediate in the synthesis of enzyme inhibitors, amino acid derivatives, and potential drug candidates. Its exceptional reactivity and functional groups make it a valuable tool for researchers and chemists engaged in the development of novel substances with diverse biological activities.

Literature

• Plasma citrulline is a sensitive safety biomarker for small intestinal injury in rats.

  Toxicology letters 20181001

• Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

  Nature chemical biology 20150301

• Endothelial arginine resynthesis contributes to the maintenance of vasomotor function in male diabetic mice.

  PloS one 20140101

• Effect of ethanol and low pH on citrulline and ornithine excretion and arc gene expression by strains of Lactobacillus brevis and Pediococcus pentosaceus.

  Food microbiology 20130201

• Leucine and citrulline: two major regulators of protein turnover.

  World review of nutrition and dietetics 20130101

• Ageing alters behavioural function and brain arginine metabolism in male Sprague-Dawley rats.

  Neuroscience 20121213

• Glucagon-like peptide-2 (GLP-2) increases net amino acid utilization by the portal-drained viscera of ruminating calves.

  Animal : an international journal of animal bioscience 20121201

• Dexamethasone significantly attenuates sub-arachnoid hemorrhage-induced elevation in cerebrospinal fluid citrulline and leukocytes.

  Journal of neurosurgical sciences 20121201

• Quantification of citrullination by means of skewed isotope distribution pattern.

  Journal of proteome research 20121102

• Expression of endothelial nitric oxide synthase protein is not necessary for mechanical strain-induced nitric oxide production by cultured osteoblasts.

  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20121101

• Metabolomic biomarkers in women with polycystic ovary syndrome: a pilot study.

  Molecular human reproduction 20121101

• Citrulline and arginine utility in treating nitric oxide deficiency in mitochondrial disorders.

  Molecular genetics and metabolism 20121101

• Effects of supplementation on food intake, body weight and hepatic metabolites in the citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mouse model of human citrin deficiency.

  Molecular genetics and metabolism 20121101

• Brassica juncea nitric oxide synthase like activity is stimulated by PKC activators and calcium suggesting modulation by PKC-like kinase.

  Plant physiology and biochemistry : PPB 20121101

• A randomized controlled trial to evaluate the effects of high-dose versus low-dose of arginine therapy on hepatic function tests in argininosuccinic aciduria.

  Molecular genetics and metabolism 20121101

• Seeing citrulline: development of a phenylglyoxal-based probe to visualize protein citrullination.

  Journal of the American Chemical Society 20121017

• ATP induces protein arginine deiminase 2-dependent citrullination in mast cells through the P2X7 purinergic receptor.

  Journal of immunology (Baltimore, Md. : 1950) 20121015

• Crystal structures of arginine kinase in complex with ADP, nitrate, and various phosphagen analogs.

  Biochemical and biophysical research communications 20121012

• A biophysical model of the mitochondrial ATP-Mg/P(i) carrier.

  Biophysical journal 20121003

• Urinary citrulline in very low birth weight preterm infants receiving intravenous nutrition.

  The British journal of nutrition 20121001

• An in silico model of enterocytic glutamine to citrulline conversion pathway.

  Amino acids 20121001

• Diet-induced weight loss in overweight or obese women and changes in high-density lipoprotein levels and function.

  Obesity (Silver Spring, Md.) 20121001

• Multifactorial risk factor intervention in patients with Type 2 diabetes improves arginine bioavailability ratios.

  Diabetic medicine : a journal of the British Diabetic Association 20121001

• eNOS overexpression exacerbates vascular closure in the obliterative phase of OIR and increases angiogenic drive in the subsequent proliferative stage.

  Investigative ophthalmology & visual science 20121001

• High sensitivity measurement of amino acid isotope enrichment using liquid chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120915

• Simultaneous measurement of protein-bound 3-chlorotyrosine and homocitrulline by LC-MS/MS after hydrolysis assisted by microwave: application to the study of myeloperoxidase activity during hemodialysis.

  Talanta 20120915

• Sustained generation of nitric oxide and control of mycobacterial infection requires argininosuccinate synthase 1.

  Cell host & microbe 20120913

• Continuous exposure to L-arginine induces oxidative stress and physiological tolerance in cultured human endothelial cells.

  Amino acids 20120901

• Effects of leucine and citrulline versus non-essential amino acids on muscle protein synthesis in fasted rat: a common activation pathway?

  Amino acids 20120901

• Understanding pyrroline-5-carboxylate synthetase deficiency: clinical, molecular, functional, and expression studies, structure-based analysis, and novel therapy with arginine.

  Journal of inherited metabolic disease 20120901

• Reassessment of a suggested pharmacological approach to heart failure: L-arginine is only a marginal NO donor in pigs.

  Journal of cardiovascular pharmacology 20120901

• Adhesive properties and inflammatory potential of citrullinated myelin basic protein peptide 45-89.

  Neurochemical research 20120901

• Online photolytic optical gating of caged fluorophores in capillary zone electrophoresis utilizing an ultraviolet light-emitting diode.

  Electrophoresis 20120901

• Structure of anabolic ornithine carbamoyltransferase from Campylobacter jejuni at 2.7 Å resolution.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20120901

• Dysregulation of dimethylargininedimethylaminohydrolase/asymmetric dimethylarginine pathway in rat type II diabetic nephropathy.

  Journal of clinical biochemistry and nutrition 20120901

• Citrullination of histone H3 interferes with HP1-mediated transcriptional repression.

  PLoS genetics 20120901

• Interactions between the NO-citrulline cycle and brain-derived neurotrophic factor in differentiation of neural stem cells.

  The Journal of biological chemistry 20120824

• Nitric oxide and L-arginine metabolism in a devascularized porcine model of acute liver failure.

  American journal of physiology. Gastrointestinal and liver physiology 20120801

• L-citrulline prevents alveolar and vascular derangement in a rat model of moderate hyperoxia-induced lung injury.

  Lung 20120801

• Plasma citrulline in Crohn's disease as a marker of inflammation or disease localization.

  Journal of clinical gastroenterology 20120801

• Up regulation of nitric oxide synthase-nitric oxide system in the testis of rats undergoing autoimmune orchitis.

  Immunobiology 20120801

• Prolonged hypoxia augments L-citrulline transport by system A in the newborn piglet pulmonary circulation.

  Cardiovascular research 20120801

• Is there a correlation between circulating levels of citrulline and intestinal dysfunction in the critically ill?

  Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 20120801

• Angiotensin-(1-7) inhibits neuronal activity of dorsolateral periaqueductal gray via a nitric oxide pathway.

  Neuroscience letters 20120801

• New insights into the genetics of immune responses in rheumatoid arthritis.

  Tissue antigens 20120801

• The first Korean case of lysinuric protein intolerance: presented with short stature and increased somnolence.

  Journal of Korean medical science 20120801

• Assessment of total- and partial-body irradiation in a baboon model: preliminary results of a kinetic study including clinical, physical, and biological parameters.

  Health physics 20120801

• Role of specific dietary amino acids in clinical conditions.

  The British journal of nutrition 20120801

• Protein kinase Cα phosphorylates a novel argininosuccinate synthase site at serine 328 during calcium-dependent stimulation of endothelial nitric-oxide synthase in vascular endothelial cells.

  The Journal of biological chemistry 20120727

• Peptidylarginine deiminase modulates the physiological roles of enolase via citrullination: links between altered multifunction of enolase and neurodegenerative diseases.

  The Biochemical journal 20120715

• Electron paramagnetic resonance characterization of tetrahydrobiopterin radical formation in bacterial nitric oxide synthase compared to mammalian nitric oxide synthase.

  Biophysical journal 20120703

• Regulatory role for L-arginine in the utilization of amino acids by pig small-intestinal bacteria.

  Amino acids 20120701

• Plasma citrulline levels in preterm neonates with necrotizing enterocolitis.

  Early human development 20120701

• Evaluation of asymmetric dimethylarginine, arginine, and carnitine metabolism in pediatric sepsis.

  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20120701

• Differential effects of chronic hyperammonemia on modulation of the glutamate-nitric oxide-cGMP pathway by metabotropic glutamate receptor 5 and low and high affinity AMPA receptors in cerebellum in vivo.

  Neurochemistry international 20120701

• Plasma amino acid levels discriminate between control subjects and mildly depressed elderly women.

  Archives of medical research 20120701

• [Synergetic activation of the nucleus accumbens nirtergic system by dopamine D1 and D2 receptor agonists].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20120701

• Novel cathepsin B-sensitive paclitaxel conjugate: Higher water solubility, better efficacy and lower toxicity.

  Journal of controlled release : official journal of the Controlled Release Society 20120628

• Ethanol transiently suppresses choline-acetyltransferase in basal nucleus of Meynert slices.

  Brain research 20120612

• Long-term enteral arginine supplementation in rats with intestinal ischemia and reperfusion.

  The Journal of surgical research 20120601

• L-arginine is a radioprotector for hematopoietic progenitor cells.

  Radiation research 20120601

• Impact of carbamylation and glycation of collagen type I on migration of HT1080 human fibrosarcoma cells.

  International journal of oncology 20120601

• Watermelon extract supplementation reduces ankle blood pressure and carotid augmentation index in obese adults with prehypertension or hypertension.

  American journal of hypertension 20120601

• Nitric oxide in the regulation of the sleep-wake states.

  Sleep medicine reviews 20120601

• A novel biochemically salvageable animal model of hyperammonemia devoid of N-acetylglutamate synthase.

  Molecular genetics and metabolism 20120601

• Melatonin synthetic analogs as nitric oxide synthase inhibitors.

  Mini reviews in medicinal chemistry 20120601

• Neuronal PAD4 expression and protein citrullination: possible role in production of autoantibodies associated with neurodegenerative disease.

  Journal of autoimmunity 20120601

• Crystallization and preliminary X-ray crystallographic analysis of human peptidylarginine deiminase type III.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20120601

• Angiotensin-(1-7) upregulates central nitric oxide synthase in spontaneously hypertensive rats.

  Brain research 20120509

• Urinary asymmetric dimethylarginine (ADMA) is a predictor of mortality risk in patients with coronary artery disease.

  International journal of cardiology 20120503

• Aging affects L-arginine and its metabolites in memory-associated brain structures at the tissue and synaptoneurosome levels.

  Neuroscience 20120503

• Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate.

  Rheumatology international 20120501

• Argininosuccinate lyase deficiency.

  Genetics in medicine : official journal of the American College of Medical Genetics 20120501

• Influence of maternal metabolism and parental genetics on fetal maldevelopment in diabetic rat pregnancy.

  American journal of physiology. Endocrinology and metabolism 20120501

• Dopamine agonist-induced penile erection and yawning: differential role of D₂-like receptor subtypes and correlation with nitric oxide production in the paraventricular nucleus of the hypothalamus of male rats.

  Behavioural brain research 20120501

• Lysinuric protein intolerance (LPI): a multi organ disease by far more complex than a classic urea cycle disorder.

  Molecular genetics and metabolism 20120501

• Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin.

  The Journal of clinical investigation 20120501

• Hyperammonemia in a patient with late-onset ornithine carbamoyltransferase deficiency.

  Journal of Korean medical science 20120501

• Five-year outcomes after serial transverse enteroplasty in children with short bowel syndrome.

  Journal of pediatric surgery 20120501

• Toward personalized hemodialysis by low molecular weight amino-containing compounds: future perspective of patient metabolic fingerprint.

  Blood transfusion = Trasfusione del sangue 20120501

• Oxygen activation in neuronal NO synthase: resolving the consecutive mono-oxygenation steps.

  The Biochemical journal 20120415

• Fluvastatin upregulates endothelial nitric oxide synthase activity via enhancement of its phosphorylation and expression and via an increase in tetrahydrobiopterin in vascular endothelial cells.

  International journal of cardiology 20120405

• Leucine and citrulline modulate muscle function in malnourished aged rats.

  Amino acids 20120401

• Expression and function of arginine-producing and consuming-enzymes in the kidney.

  Amino acids 20120401

• Plasma citrulline concentration as a marker for disease activity in patients with Crohn's disease.

  Journal of clinical gastroenterology 20120401

• Absence of post-prandial gut anabolism after intake of a low quality protein meal.

  Clinical nutrition (Edinburgh, Scotland) 20120401

• The role of inducible nitric oxide synthase and haem oxygenase 1 in growth and development of dental tissue'.

  Cell biochemistry and function 20120401

• Endotoxemia exacerbates kidney injury and increases asymmetric dimethylarginine in young bile duct-ligated rats.

  Shock (Augusta, Ga.) 20120401

• N-Carbamoylputrescine, a citrulline-derived polyamine, is not a significant citrulline metabolite in rats.

  Analytical biochemistry 20120401

• Increased leukocyte Rho-associated coiled-coil containing protein kinase activity predicts the presence and severity of coronary vasospastic angina.

  Atherosclerosis 20120401

• Restoration of impaired nitric oxide production in MELAS syndrome with citrulline and arginine supplementation.

  Molecular genetics and metabolism 20120401

• Production of autoantibodies against citrullinated antigens/peptides by human B cells.

  Journal of immunology (Baltimore, Md. : 1950) 20120401

• Evaluation of potential gastrointestinal biomarkers in a PAK4 inhibitor-treated preclinical toxicity model to address unmonitorable gastrointestinal toxicity.

  Toxicologic pathology 20120401

• Unrecognized citrullinemia mimicking encephalitis in a 14-year-old boy: unexpected result through the use of a standardized lumbar puncture protocol.

  Neuropediatrics 20120401

• Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation.

  PLoS biology 20120401

• [Mediolateral gradient of the nucleus accumbens nitrergic activation during exploratory behavior].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20120401

• Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men.

  International journal of cardiology 20120308

• Peptides induce persistent signaling from endosomes by a nutrient transceptor.

  Nature chemical biology 20120304

• Endotoxemia affects citrulline, arginine and glutamine bioavailability.

  European journal of clinical investigation 20120301

• Systemic L-citrulline prevents cerebral vasospasm in haptoglobin 2-2 transgenic mice after subarachnoid hemorrhage.

  Neurosurgery 20120301

• NO-dependent protective effect of VEGF against excitotoxicity on layer VI of the developing cerebral cortex.

  Neurobiology of disease 20120301

• Nitric oxide synthase and tyrosine nitration in idiopathic asthenozoospermia: an immunohistochemical study.

  Fertility and sterility 20120301

• The role of deimination in ATP5b mRNA transport in a transgenic mouse model of multiple sclerosis.

  EMBO reports 20120301

• Year in review in Intensive Care Medicine 2011. II. Cardiovascular, infections, pneumonia and sepsis, critical care organization and outcome, education, ultrasonography, metabolism and coagulation.

  Intensive care medicine 20120301

• Periodontitis, Porphyromonas, and the pathogenesis of rheumatoid arthritis.

  Mucosal immunology 20120301

• Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal Problems.

  Intensive care medicine 20120301

• In vivo relevance of citrullinated proteins and the challenges in their detection.

  Proteomics 20120301

• Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming.

  PLoS pathogens 20120301

• Correlative analysis of neoplasm patients with phlegm-stasis or abnormal Savda syndrome, based on metabonomics.

  Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20120301

• [Influence of D2-receptor blockade on the nitrergic system activity of the nucleus accumbens].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20120301

• Lactic acid bacteria isolated from apples are able to catabolise arginine.

  World journal of microbiology & biotechnology 20120301

• Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.

  Nature communications 20120214

• Effects of nitric oxide on the survival and neuritogenesis of cerebellar Purkinje neurons.

  Journal of molecular neuroscience : MN 20120201

• Peptidylarginine deiminases present in the airways during tobacco smoking and inflammation can citrullinate the host defense peptide LL-37, resulting in altered activities.

  American journal of respiratory cell and molecular biology 20120201

• Rheumatoid arthritis and periodontitis: a possible link via 'citation'.

  Anaerobe 20120201

• Partial deletion of argininosuccinate synthase protects from pyrazole plus lipopolysaccharide-induced liver injury by decreasing nitrosative stress.

  American journal of physiology. Gastrointestinal and liver physiology 20120201

• Quantification of plasma homocitrulline using hydrophilic interaction liquid chromatography (HILIC) coupled to tandem mass spectrometry.

  Analytical and bioanalytical chemistry 20120201

• Determination of nonprotein amino acids and betaines in vegetable oils by flow injection triple-quadrupole tandem mass spectrometry: a screening method for the detection of adulterations of olive oils.

  Journal of agricultural and food chemistry 20120201

• Neuronal nitric oxide synthase, nNOS, regulates renal hemodynamics in the postnatal developing piglet.

  Pediatric research 20120201

• The effect of nitric-oxide-related supplements on human performance.

  Sports medicine (Auckland, N.Z.) 20120201

• Recombinant human arginase toxicity in mice is reduced by citrulline supplementation.

  Translational oncology 20120201

• Effect of anti-rheumatic agents on periodontal parameters and biomarkers of inflammation: a systematic review and meta-analysis.

  Journal of periodontal & implant science 20120201

• The influence of ACPA status and characteristics on the course of RA.

  Nature reviews. Rheumatology 20120131

• Mutated citrullinated vimentin antibodies in rheumatoid arthritis.

  Clinica chimica acta; international journal of clinical chemistry 20120118

• Age-related changes in serum amino acids concentrations in healthy individuals.

  Clinical chemistry and laboratory medicine 20120104

• Anti-mutated citrullinated vimentin (anti-MCV) and anti-65 kDa heat shock protein (anti-hsp65): new biomarkers in ankylosing spondylitis.

  Joint, bone, spine : revue du rhumatisme 20120101

• Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy.

  Advances in hematology 20120101

• Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis.

  Annals of the rheumatic diseases 20120101

• Nonimmune Cells Contribute to Crosstalk between Immune Cells and Inflammatory Mediators in the Innate Response to Trypanosoma cruzi Infection.

  Journal of parasitology research 20120101

• Human traumatic brain injury alters circulating L-arginine and its metabolite levels: possible link to cerebral blood flow, extracellular matrix remodeling, and energy status.

  Journal of neurotrauma 20120101

• 18F-FDG PET/CT for diagnosing infectious complications in patients with severe neutropenia after intensive chemotherapy for haematological malignancy or stem cell transplantation.

  European journal of nuclear medicine and molecular imaging 20120101

• The effects of modulating eNOS activity and coupling in ischemia/reperfusion (I/R).

  Naunyn-Schmiedeberg's archives of pharmacology 20120101

• Cytotoxicity of human recombinant arginase I (Co)-PEG5000 in the presence of supplemental L-citrulline is dependent on decreased argininosuccinate synthetase expression in human cells.

  Anti-cancer drugs 20120101

• Pretreatment with citrulline improves gut barrier after intestinal obstruction in mice.

  JPEN. Journal of parenteral and enteral nutrition 20120101

• Arginases and arginine deficiency syndromes.

  Current opinion in clinical nutrition and metabolic care 20120101

• Expression of bleomycin hydrolase in keratinization disorders.

  Archives of dermatological research 20120101

• Methods for analyzing histone citrullination in chromatin structure and gene regulation.

  Methods in molecular biology (Clifton, N.J.) 20120101

• Spectroscopic, catalytic and binding properties of Bacillus subtilis NO synthase-like protein: comparison with other bacterial and mammalian NO synthases.

  Journal of inorganic biochemistry 20120101

• Sequential injection chromatography for fluorimetric determination of intracellular amino acids in marine microalgae.

  Methods in molecular biology (Clifton, N.J.) 20120101

• Host cell signalling and leishmania mechanisms of evasion.

  Journal of tropical medicine 20120101

• Peripartum management of two parturients with ornithine transcarbamylase deficiency.

  International journal of obstetric anesthesia 20120101

• Systemic arginine depletion after a murine model of surgery or trauma.

  JPEN. Journal of parenteral and enteral nutrition 20120101

• New advances in the management of children with intestinal failure.

  JPEN. Journal of parenteral and enteral nutrition 20120101

• Glutaminase immunoreactivity and enzyme activity is increased in the rat dorsal root ganglion following peripheral inflammation.

  Pain research and treatment 20120101

• Inhibition of endothelial- and neuronal-type, but not inducible-type, nitric oxide synthase by the oxidized cholesterol metabolite secosterol aldehyde: Implications for vascular and neurodegenerative diseases.

  Journal of clinical biochemistry and nutrition 20120101

• Emerging Pharmacotherapy for Relapsed or Refractory Hodgkin's Lymphoma: Focus on Brentuximab Vedotin.

  Clinical Medicine Insights. Oncology 20120101

• Arginase inhibition alleviates hypertension associated with diabetes: effect on endothelial dependent relaxation and NO production.

  Vascular pharmacology 20120101

• Metal toxicity at the synapse: presynaptic, postsynaptic, and long-term effects.

  Journal of toxicology 20120101

• eNOS protects from atherosclerosis despite relevant superoxide production by the enzyme in apoE mice.

  PloS one 20120101

• Calcimimetic R-568 and its enantiomer S-568 increase nitric oxide release in human endothelial cells.

  PloS one 20120101

• Pegylated arginine deiminase downregulates colitis in murine models.

  Mediators of inflammation 20120101

• Accelerated growth rate induced by neonatal high-protein milk formula is not supported by increased tissue protein synthesis in low-birth-weight piglets.

  Journal of nutrition and metabolism 20120101

• Endogenous urotensin II selectively modulates erectile function through eNOS.

  PloS one 20120101

• Anti-citrullinated fibronectin antibodies in rheumatoid arthritis are associated with human leukocyte antigen-DRB1 shared epitope alleles.

  Arthritis research & therapy 20120101

• A preliminary study on protective effect of L-citrulline against ischemia-reperfusion induced gastric mucosal lesions in rat.

  Indian journal of pharmacology 20120101

• Rheumatoid arthritis and periodontitis - inflammatory and infectious connections. Review of the literature.

  Journal of oral microbiology 20120101

• Nitration of the pollen allergen bet v 1.0101 enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells.

  PloS one 20120101

• Efficacy of different nitric oxide-based strategies in preventing experimental cerebral malaria by Plasmodium berghei ANKA.

  PloS one 20120101

• Metabolite profiling of Alzheimer's disease cerebrospinal fluid.

  PloS one 20120101

• Anandamide induces sperm release from oviductal epithelia through nitric oxide pathway in bovines.

  PloS one 20120101

• New insight into the transcarbamylase family: the structure of putrescine transcarbamylase, a key catalyst for fermentative utilization of agmatine.

  PloS one 20120101

• Screening for inborn errors of metabolism in high-risk children: a 3-year pilot study in Zhejiang Province, China.

  BMC pediatrics 20120101

• Myocardial citrullination in rheumatoid arthritis: a correlative histopathologic study.

  Arthritis research & therapy 20120101

• Protease-activated drug development.

  Theranostics 20120101

• ArgR of Streptomyces coelicolor is a versatile regulator.

  PloS one 20120101

• Regulation of eNOS in caveolae.

  Advances in experimental medicine and biology 20120101

• [Rheumatic diseases and research on laboratory medicine: new applications of old knowledge].

  Rinsho byori. The Japanese journal of clinical pathology 20120101

• Pilot study of the association of the DDAH2 -449G polymorphism with asymmetric dimethylarginine and hemodynamic shock in pediatric sepsis.

  PloS one 20120101

• L-arginine supplementation improves responses to injury and inflammation in dextran sulfate sodium colitis.

  PloS one 20120101

• Biomarker discovery by novel sensors based on nanoproteomics approaches.

  Sensors (Basel, Switzerland) 20120101

• Nebivolol: impact on cardiac and endothelial function and clinical utility.

  Vascular health and risk management 20120101

• The regulatory repertoire of Pseudomonas aeruginosa AmpC ß-lactamase regulator AmpR includes virulence genes.

  PloS one 20120101

• Nitric oxide-driven hypoxia initiates synovial angiogenesis, hyperplasia and inflammatory lesions in mice.

  PloS one 20120101

• Myocardial dysfunction in sepsis: a large, unsolved puzzle.

  Critical care research and practice 20120101

• Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes.

  International journal of vascular medicine 20120101

• Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways.

  PloS one 20120101

• Comparative analysis of peptidylarginine deiminase-2 expression in canine, feline and human mammary tumours.

  Journal of comparative pathology 20120101

• Solar radiation and vitamin D: mitigating environmental factors in autoimmune disease.

  Journal of environmental and public health 20120101

• Chemically modified tetracyclines: Novel therapeutic agents in the management of chronic periodontitis.

  Indian journal of pharmacology 20120101

• DNA aptamers against the Lup an 1 food allergen.

  PloS one 20120101

• Nitric oxide synthases and atrial fibrillation.

  Frontiers in physiology 20120101

• Nitric oxide manipulation: a therapeutic target for peripheral arterial disease?

  Cardiology research and practice 20120101

• A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with insulin sensitivity.

  PloS one 20120101

• The influence of autonomic dysfunction associated with aging and type 2 diabetes on daily life activities.

  Experimental diabetes research 20120101

• Reactive oxygen species and nitric oxide in cutaneous leishmaniasis.

  Journal of parasitology research 20120101

• Association of oxidative stress markers with atherogenic index of plasma in adult sickle cell nephropathy.

  Anemia 20120101

• Pharmacogenetics meets metabolomics: discovery of tryptophan as a new endogenous OCT2 substrate related to metformin disposition.

  PloS one 20120101

• Impact of environmental thermal stimulation on activation of hypothalamic neuronal nitric oxide synthase during the prenatal ontogenesis in Muscovy ducks.

  TheScientificWorldJournal 20120101

• Anti citrullinated protein antibodies and mechanism of action of common disease modifying drugs--insights in pathomechanisms of autoimmunity.

  Current pharmaceutical design 20120101

• L-arginine and asymmetric dimethylarginine are early predictors for survival in septic patients with acute liver failure.

  Mediators of inflammation 20120101

• The plant mitochondrial carrier family: functional and evolutionary aspects.

  Frontiers in plant science 20120101

• Investigation of serum amino acid and serum amyloid A concentrations in chickens with amyloid arthropathy.

  The Veterinary quarterly 20120101

• Do the interactions between glucocorticoids and sex hormones regulate the development of the metabolic syndrome?

  Frontiers in endocrinology 20120101

• Prenatal hyperandrogenization induces metabolic and endocrine alterations which depend on the levels of testosterone exposure.

  PloS one 20120101

• Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis.

  PloS one 20120101

• Citrulline a more suitable substrate than arginine to restore NO production and the microcirculation during endotoxemia.

  PloS one 20120101

• The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection.

  Oxidative medicine and cellular longevity 20120101

• Genetics Techniques for Thermococcus kodakarensis.

  Frontiers in microbiology 20120101

• Potential role for PADI-mediated histone citrullination in preimplantation development.

  BMC developmental biology 20120101

• Lobe-specific calcium binding in calmodulin regulates endothelial nitric oxide synthase activation.

  PloS one 20120101

• Successful prospective management of neonatal citrullinemia.

  Journal of pediatric endocrinology & metabolism : JPEM 20120101

• Role for peptidylarginine deiminase enzymes in disease and female reproduction.

  The Journal of reproduction and development 20120101

• Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment.

  PloS one 20120101

• L-citrulline supplementation reverses the impaired airway relaxation in neonatal rats exposed to hyperoxia.

  Respiratory research 20120101

• Potential role for PAD2 in gene regulation in breast cancer cells.

  PloS one 20120101

• Detection of nitric oxide and superoxide radical anion by electron paramagnetic resonance spectroscopy from cells using spin traps.

  Journal of visualized experiments : JoVE 20120101

• Interferon-gamma-induced nitric oxide inhibits the proliferation of murine renal cell carcinoma cells.

  International journal of biological sciences 20120101

• Arginine consumption by the intestinal parasite Giardia intestinalis reduces proliferation of intestinal epithelial cells.

  PloS one 20120101

• [Signals of danger inhibit exploration-induced activation of the nitrergic system of the nucleus accumbens].

  Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20120101

• PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures.

  Frontiers in immunology 20120101

• Neonatal intrahepatic cholestasis caused by citrin deficiency: prevalence and SLC25A13 mutations among Thai infants.

  BMC gastroenterology 20120101

• Arginine and citrulline supplementation in sports and exercise: ergogenic nutrients?

  Medicine and sport science 20120101

• Asymmetric dimethylarginine, endothelial dysfunction and renal disease.

  International journal of molecular sciences 20120101

• Citrullination of autoantigens: upstream of TNFα in the pathogenesis of rheumatoid arthritis.

  FEBS letters 20111201

• Early-onset hepatic fibrosis in lysinuric protein intolerance.

  Journal of pediatric gastroenterology and nutrition 20111201

• Oral citrulline does not affect whole body protein metabolism in healthy human volunteers: results of a prospective, randomized, double-blind, cross-over study.

  Clinical nutrition (Edinburgh, Scotland) 20111201

• Ornithine transcarbamylase deficiency diagnosed in pregnancy.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20111201

• Effects of heavy metal cations on the mitochondrial ornithine/citrulline transporter reconstituted in liposomes.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20111201

• The antigen specificity of the rheumatoid arthritis-associated ACPA directed to citrullinated fibrin is very closely restricted.

  Journal of autoimmunity 20111201

• Scopolamine impairs behavioural function and arginine metabolism in the rat dentate gyrus.

  Neuropharmacology 20111201

• Metabolomic analysis reveals hepatic metabolite perturbations in citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mice, a model of human citrin deficiency.

  Molecular genetics and metabolism 20111201

• Oxygen-dependent regulation of nitric oxide production by inducible nitric oxide synthase.

  Free radical biology & medicine 20111201

• Hypoxia-reduced nitric oxide synthase activity is partially explained by higher arginase-2 activity and cellular redistribution in human umbilical vein endothelium.

  Placenta 20111201

• Characterization of alpha-amino-n-butyric acid correlations in sepsis.

  Translational research : the journal of laboratory and clinical medicine 20111201

• Prenatal diagnosis of citrin deficiency in a Chinese family with a fatal proband.

  The Tohoku journal of experimental medicine 20111201

• Autoantibodies in early rheumatoid arthritis: Brasília cohort: results of a three-year serial analysis.

  Revista brasileira de reumatologia 20111201

• Anti-citrullinated peptide antibodies and rheumatoid factor in Sudanese patients with Leishmania donovani infection.

  Revista brasileira de reumatologia 20111201

• Plasma citrulline concentration as a biomarker for bowel loss and adaptation in hospitalized pediatric patients requiring parenteral nutrition.

  Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 20111201

• Effect of probiotic bacteria on microbial host defense, growth, and immune function in human immunodeficiency virus type-1 infection.

  Nutrients 20111201

• Influence of wine-like conditions on arginine utilization by lactic acid bacteria.

  International microbiology : the official journal of the Spanish Society for Microbiology 20111201

• Arginine or citrulline associated with a statin stimulates nitric oxide production in bovine aortic endothelial cells.

  European journal of pharmacology 20111130

• Nitric oxide synthase is not expressed, nor up-regulated in response to cold acclimation in liver or muscle of threespine stickleback (Gasterosteus aculeatus).

  Nitric oxide : biology and chemistry 20111130

• Influence of heme-thiolate in shaping the catalytic properties of a bacterial nitric-oxide synthase.

  The Journal of biological chemistry 20111111

• The use of chimeric vimentin citrullinated peptides for the diagnosis of rheumatoid arthritis.

  Journal of medicinal chemistry 20111110

• Intracellular L-arginine concentration does not determine NO production in endothelial cells: implications on the 'L-arginine paradox'.

  Biochemical and biophysical research communications 20111104

• Antibodies against cyclic citrullinated peptide don't decrease after 6 months of infliximab treatment in refractory rheumatoid arthritis.

  Rheumatology international 20111101

• Defective leptin-AMP-dependent kinase pathway induces nitric oxide release and contributes to mitochondrial dysfunction and obesity in ob/ob mice.

  Antioxidants & redox signaling 20111101

• Plasma citrulline as surrogate marker of intestinal inflammation in pediatric and adolescent with Crohn's disease: preliminary report.

  International journal of colorectal disease 20111101

• Relative contribution of different l-arginine sources to the substrate supply of endothelial nitric oxide synthase.

  Journal of molecular and cellular cardiology 20111101

• Plasma citrulline levels predict intestinal toxicity in patients treated with pelvic radiotherapy.

  Acta oncologica (Stockholm, Sweden) 20111101

• Glutamine as an immunonutrient.

  Yonsei medical journal 20111101

• Orally administered L-ornithine elevates brain L-ornithine levels and has an anxiolytic-like effect in mice.

  Nutritional neuroscience 20111101

• Modeling gas phase nitric oxide release in lung epithelial cells.

  Nitric oxide : biology and chemistry 20111030

• Site-specific incorporation of arginine analogs into proteins using arginyl-tRNA synthetase.

  Biochemical and biophysical research communications 20111028

• Generation, translocation, and action of nitric oxide in living systems.

  Chemistry & biology 20111028

• Pre-aggregated Aβ(25-35) alters arginine metabolism in the rat hippocampus and prefrontal cortex.

  Neuroscience 20111013

• Clickable enzyme-linked immunosorbent assay.

  Biomacromolecules 20111010

• Ureido-derivatized polymers based on both poly(allylurea) and poly(L-citrulline) exhibit UCST-type phase transition behavior under physiologically relevant conditions.

  Biomacromolecules 20111010

• Citrulline levels in premature infants.

  Clinica chimica acta; international journal of clinical chemistry 20111009

• Genetic dysregulation of glutathione synthesis predicts alteration of plasma thiol redox status in schizophrenia.

  Antioxidants & redox signaling 20111001

• The diagnostic value of CRP, IL-8, PCT, and sTREM-1 in the detection of bacterial infections in pediatric oncology patients with febrile neutropenia.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20111001

• A role for PPARα in the regulation of arginine metabolism and nitric oxide synthesis.

  Amino acids 20111001

• Plasma citrulline as marker of bowel adaptation in children with short bowel syndrome.

  Langenbeck's archives of surgery 20111001

• Biomarkers of regimen-related mucosal injury.

  Cancer treatment reviews 20111001

• A continuous, fluorescent, high-throughput assay for human dimethylarginine dimethylaminohydrolase-1.

  Journal of biomolecular screening 20111001

• Hydrogen peroxide: a Jekyll and Hyde signalling molecule.

  Cell death & disease 20111001

• Enantiomeric separation of FMOC-amino acids by nano-LC and CEC using a new chiral stationary phase, cellulose tris(3-chloro-4-methylphenylcarbamate).

  Electrophoresis 20111001

• Citrulline: a potential immunomodulator in sepsis.

  Surgery 20111001

• Acute treatment of hyperammonemia by continuous renal replacement therapy in a newborn patient with ornithine transcarbamylase deficiency.

  Korean journal of pediatrics 20111001

• Profile of plasma amino Acid levels in rats exposed to acute hypoxic hypoxia.

  Indian journal of clinical biochemistry : IJCB 20111001

• Dietary arginine depletion reduces depressive-like responses in male, but not female, mice.

  Behavioural brain research 20110930

• Citrulline malate supplementation increases muscle efficiency in rat skeletal muscle.

  European journal of pharmacology 20110930

• Carbon nanotube composite peptide-based biosensors as putative diagnostic tools for rheumatoid arthritis.

  Biosensors & bioelectronics 20110915

• Differential modulation of the glutamate-nitric oxide-cyclic GMP pathway by distinct neurosteroids in cerebellum in vivo.

  Neuroscience 20110908

• Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling.

  British journal of pharmacology 20110901

• 3-nitro-tyrosine as a peripheral biomarker of minimal hepatic encephalopathy in patients with liver cirrhosis.

  The American journal of gastroenterology 20110901

• Genome-wide and species-wide dissection of the genetics of arthritis severity in heterogeneous stock mice.

  Arthritis and rheumatism 20110901

• Arginine bioavailability ratios are associated with cardiovascular mortality in patients referred to coronary angiography.

  Atherosclerosis 20110901

• In vitro and in vivo responses of advanced prostate tumors to PSMA ADC, an auristatin-conjugated antibody to prostate-specific membrane antigen.

  Molecular cancer therapeutics 20110901

• Identification of citrullinated histone H3 as a potential serum protein biomarker in a lethal model of lipopolysaccharide-induced shock.

  Surgery 20110901

• Pharmaconutrition for the obese, critically ill patient.

  JPEN. Journal of parenteral and enteral nutrition 20110901

• Ornithine transcarbamylase deficiency presenting as recurrent abdominal pain in childhood.

  Pediatric emergency care 20110901

• Advances in the management of pediatric pulmonary hypertension.

  Respiratory care 20110901

• Chemical and metabolic aspects of antimetabolite toxins produced by Pseudomonas syringae pathovars.

  Toxins 20110901

• Was citrulline first a laxative substance? The truth about modern citrulline and its isolation.

  Nihon ishigaku zasshi. [Journal of Japanese history of medicine] 20110901

• The link between erectile and cardiovascular health: the canary in the coal mine.

  The American journal of cardiology 20110815

• Measurement of in vivo nitric oxide synthesis in humans using stable isotopic methods: a systematic review.

  Free radical biology & medicine 20110815

• The effect of nNOS inhibitors on toxin-induced cell death in dopaminergic cell lines depends on the extent of enzyme expression.

  Brain research 20110802

• Amino acid profile during exercise and training in Standardbreds.

  Research in veterinary science 20110801

• New insights on the mechanisms of valproate-induced hyperammonemia: inhibition of hepatic N-acetylglutamate synthase activity by valproyl-CoA.

  Journal of hepatology 20110801

• Calcium/calmodulin-dependent protein kinases as potential targets of nitric oxide.

  Nitric oxide : biology and chemistry 20110801

• Increased arginase activity contributes to airway remodelling in chronic allergic asthma.

  The European respiratory journal 20110801

• Metabolic cutis laxa syndromes.

  Journal of inherited metabolic disease 20110801

• Surfactant blocks lipopolysaccharide signaling by inhibiting both NFκB and PARP activation in experimental ARDS.

  Molecular and cellular biochemistry 20110801

• Rheumatoid arthritis and periodontitis; a possible link via citrullination.

  Anaerobe 20110801

• Arginine synthesis from enteral glutamine in healthy adults in the fed state.

  American journal of physiology. Endocrinology and metabolism 20110801

• Genetics of rheumatoid arthritis: what have we learned?

  Immunogenetics 20110801

• Is glutamine still an important precursor of citrulline?

  American journal of physiology. Endocrinology and metabolism 20110801

• Time-dependent changes in the plasma amino acid concentration in diabetes mellitus.

  Molecular genetics and metabolism 20110801

• Inducible nitric oxide synthase (iNOS) in muscle wasting syndrome, sarcopenia, and cachexia.

  Aging 20110801

• Association analysis of anti-Epstein-Barr nuclear antigen-1 antibodies, anti-cyclic citrullinated peptide antibodies, the shared epitope and smoking status in Brazilian patients with rheumatoid arthritis.

  Clinics (Sao Paulo, Brazil) 20110801

• Modes of action of microbially-produced phytotoxins.

  Toxins 20110801

• A capillary electrophoresis-tandem mass spectrometry methodology for the determination of non-protein amino acids in vegetable oils as novel markers for the detection of adulterations in olive oils.

  Journal of chromatography. A 20110729

• Protein deiminases: new players in the developmentally regulated loss of neural regenerative ability.

  Developmental biology 20110715

• Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome.

  Gut 20110701

• Autopathogenic correlation of periodontitis and rheumatoid arthritis.

  Rheumatology (Oxford, England) 20110701

• Discovery of peptidylarginine deiminase-4 substrates by protein array: antagonistic citrullination and methylation of human ribosomal protein S2.

  Molecular bioSystems 20110701

• Glutamine, ornithine, citrulline and arginine levels in children with phenylketonuria: The diet effect.

  Clinical biochemistry 20110701

• The effect of L-arginine or L-citrulline supplementation on biochemical parameters and the vascular aortic wall in high-fat and high-cholesterol-fed rats.

  Cell biochemistry and function 20110701

• Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity.

  International journal of environmental research and public health 20110701

• Endothelial arginase II and atherosclerosis.

  Korean journal of anesthesiology 20110701

• New and revisited species in Aspergillus section Nigri.

  Studies in mycology 20110630

• Down-regulation of hepatic urea synthesis by oxypurines: xanthine and uric acid inhibit N-acetylglutamate synthase.

  The Journal of biological chemistry 20110624

• Modification of citrulline residues with 2,3-butanedione facilitates their detection by liquid chromatography/mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20110615

• The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis.

  Science translational medicine 20110615

• Anti-CCP antibodies: the past, the present and the future.

  Nature reviews. Rheumatology 20110607

• A GC/MS-based metabolomic approach for diagnosing citrin deficiency.

  Analytical and bioanalytical chemistry 20110601

• Acute intestinal failure in critically ill patients: is plasma citrulline the right marker?

  Intensive care medicine 20110601

• Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.

  Free radical biology & medicine 20110601

• Antibodies to a new viral citrullinated peptide, VCP2: fine specificity and correlation with anti-cyclic citrullinated peptide (CCP) and anti-VCP1 antibodies.

  Clinical and experimental immunology 20110601

• Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor.

  American journal of physiology. Gastrointestinal and liver physiology 20110601

• Synthesis of a citrulline-rich cyanophycin by use of Pseudomonas putida ATCC 4359.

  Applied microbiology and biotechnology 20110601

• Hot topics in postsmall bowel transplantation: noninvasive graft monitoring including stool calprotectin and plasma citrulline.

  Current opinion in organ transplantation 20110601

• Insulin restores gestational diabetes mellitus-reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium.

  Diabetes 20110601

• Citrulline-modified phage display: a novel high-throughput discovery approach for the identification of citrulline-containing ligands.

  Proteomics 20110601

• Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells.

  PLoS genetics 20110601

• Association of NOS3 tag polymorphisms with hypoxic-ischemic encephalopathy.

  Croatian medical journal 20110601

• Biochemical aspects of nitric oxide synthase feedback regulation by nitric oxide.

  Interdisciplinary toxicology 20110601

• [Citrulline extracellular level in the nucleus accumbens during feeding behaviour].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20110601

• Auxiliary partial orthotopic liver transplantation for adult onset type II citrullinemia.

  Journal of the Korean Surgical Society 20110601

• Quantitative analysis of 15N-labeled positional isomers of glutamine and citrulline via electrospray ionization tandem mass spectrometry of their dansyl derivatives.

  Rapid communications in mass spectrometry : RCM 20110515

• Citrullination of inhibitor of growth 4 (ING4) by peptidylarginine deminase 4 (PAD4) disrupts the interaction between ING4 and p53.

  The Journal of biological chemistry 20110513

• Dual immunofluorescence study of citrullinated proteins in Parkinson diseased substantia nigra.

  Neuroscience letters 20110509

• Reduced expression of intestinal N-acetylglutamate synthase in suckling piglets: a novel molecular mechanism for arginine as a nutritionally essential amino acid for neonates.

  Amino acids 20110501

• The swollen joint, the thickened artery, and the smoking gun: tobacco exposure, citrullination and rheumatoid arthritis.

  Rheumatology international 20110501

• Citrullinaemia type I: a common mutation in the Pacific Island population.

  Journal of paediatrics and child health 20110501

• Quantification of arginine and its metabolites in human erythrocytes using liquid chromatography-tandem mass spectrometry.

  Analytical biochemistry 20110501

• Amino Acid profiles in human tear fluids analyzed by high-performance liquid chromatography and electrospray ionization tandem mass spectrometry.

  American journal of ophthalmology 20110501

• The kinetics of the arginine deiminase pathway in the meat starter culture Lactobacillus sakei CTC 494 are pH-dependent.

  Food microbiology 20110501

• Association of anti-modified citrullinated vimentin with subclinical atherosclerosis in early rheumatoid arthritis compared with anti-cyclic citrullinated peptide.

  The Journal of rheumatology 20110501

• Simultaneous determination of 6 L-arginine metabolites in human and mouse plasma by using hydrophilic-interaction chromatography and electrospray tandem mass spectrometry.

  Clinical chemistry 20110501

• Influence of inflammation-related changes on conformational characteristics of HLA-B27 subtypes as detected by IR spectroscopy.

  The FEBS journal 20110501

• Pathophysiology of rheumatoid arthritis.

  Current opinion in rheumatology 20110501

• Varying diet alone can reduce stool output and enhance fluid and nutrient absorption.

  JPEN. Journal of parenteral and enteral nutrition 20110501

• Clinical applications of autoimmunity to citrullinated proteins in rheumatoid arthritis, from improving diagnostics to future therapies.

  Recent patents on inflammation & allergy drug discovery 20110501

• Cisapride improves enteral tolerance in pediatric short-bowel syndrome with dysmotility.

  Journal of pediatric gastroenterology and nutrition 20110501

• Protective effect of L-citrulline against acute gastric mucosal lesions induced by ischemia-reperfusion in rats.

  Canadian journal of physiology and pharmacology 20110501

• Involvement of nitric oxide in learning & memory processes.

  The Indian journal of medical research 20110501

• [Analysis of clinical features, biochemical analysis and gene mutations in one Chinese pedigree with neonatal-onset ornithine transcarbamylase deficiency].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20110501

• The complete microspeciation of arginine and citrulline.

  Journal of pharmaceutical and biomedical analysis 20110405

• Pyruvate: immunonutritional effects on neutrophil intracellular amino or alpha-keto acid profiles and reactive oxygen species production.

  Amino acids 20110401

• Interaction of nitric oxide and the cytochrome P-450 system on blood pressure and renal function in the rat: dependence on sodium intake.

  Acta physiologica (Oxford, England) 20110401

• Pathogenetic role of eNOS uncoupling in cardiopulmonary disorders.

  Free radical biology & medicine 20110401

• Transient fulminant liver failure as an initial presentation in citrullinemia type I.

  Molecular genetics and metabolism 20110401

• Metabotropic glutamate receptor 5 modulates the nitric oxide-cGMP pathway in cerebellum in vivo through activation of AMPA receptors.

  Neurochemistry international 20110401

• N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis.

  Journal of immunology (Baltimore, Md. : 1950) 20110401

• Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis.

  Seminars in immunology 20110401

• The therapeutic potential of targeting endogenous inhibitors of nitric oxide synthesis.

  Nature reviews. Drug discovery 20110401

• [Plasma metabonomics analysis of tumor patients of phlegm-stasis syndrome].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20110401

• Upregulation of cardiac NO/NOS system during short-term hypoxia and the subsequent reoxygenation period.

  European journal of histochemistry : EJH 20110401

• Role of anti-citrullinated protein antibodies in diagnosis and prognosis of rheumatoid arthritis.

  Archives of medical science : AMS 20110401

• Bioactive compounds from flesh and by-product of fresh-cut watermelon cultivars.

  Journal of the science of food and agriculture 20110330

• Adduction of cholesterol 5,6-secosterol aldehyde to membrane-bound myelin basic protein exposes an immunodominant epitope.

  Biochemistry 20110329

• Citrulline levels in a paediatric age group: does measurement on dried blood spots have additional value?

  Clinica chimica acta; international journal of clinical chemistry 20110318

• Decreased glutamine synthetase, increased citrulline-nitric oxide cycle activities, and oxidative stress in different regions of brain in epilepsy rat model.

  Journal of physiology and biochemistry 20110301

• Plasma citrulline levels in paediatric patients with celiac disease and the effect of a gluten-free diet.

  European journal of gastroenterology & hepatology 20110301

• Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice.

  Diabetes 20110301

• Simultaneous bioanalysis of L-arginine, L-citrulline, and dimethylarginines by LC-MS/MS.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110301

• Quantification of 22 plasma amino acids combining derivatization and ion-pair LC-MS/MS.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110301

• The anandamide effect on NO/cGMP pathway in human platelets.

  Journal of cellular biochemistry 20110301

• Low serum citrulline concentration correlates with catheter-related bloodstream infections in children with intestinal failure.

  JPEN. Journal of parenteral and enteral nutrition 20110301

• Effect of specimen storage conditions on newborn dried blood spots used to assess Toxoplasma gondii immunoglobulin M (IgM).

  Clinica chimica acta; international journal of clinical chemistry 20110220

• Assessment of circulating biomarkers for potential pharmacodynamic utility in patients with lymphoma.

  British journal of cancer 20110215

• Pathophysiology of sickle cell disease is mirrored by the red blood cell metabolome.

  Blood 20110210

• Are patients with potential celiac disease really potential? The answer of metabonomics.

  Journal of proteome research 20110204

• Long-term memory of visually cued fear conditioning: roles of the neuronal nitric oxide synthase gene and cyclic AMP response element-binding protein.

  Neuroscience 20110203

• Stratum corneum free amino acids following barrier perturbation and repair.

  International journal of cosmetic science 20110201

• Serum markers and intestinal mucosal injury in chronic gastrointestinal ischemia.

  Digestive diseases and sciences 20110201

• Heterologous expression of Anabaena sp. PCC7120 cyanophycin metabolism genes cphA1 and cphB1 in Sinorhizobium (Ensifer) meliloti 1021.

  Applied microbiology and biotechnology 20110201

• Statin therapy in metabolic syndrome and hypertension post-JUPITER: what is the value of CRP?

  Current atherosclerosis reports 20110201

• Acute endotoxemia following transjugular intrahepatic stent-shunt insertion is associated with systemic and cerebral vasodilatation with increased whole body nitric oxide production in critically ill cirrhotic patients.

  Journal of hepatology 20110201

• Small intestinal alterations in severely obese hyperglycemic subjects.

  The Journal of clinical endocrinology and metabolism 20110201

• Lactose maldigestion during methotrexate-induced gastrointestinal mucositis in a rat model.

  American journal of physiology. Gastrointestinal and liver physiology 20110201

• Year in review in Intensive Care Medicine 2010: II. Pneumonia and infections, cardiovascular and haemodynamics, organization, education, haematology, nutrition, ethics and miscellanea.

  Intensive care medicine 20110201

• Structural and biochemical analyses of the human PAD4 variant encoded by a functional haplotype gene.

  Acta crystallographica. Section D, Biological crystallography 20110201

• Analysis of ven3 and ven6 reticulate mutants reveals the importance of arginine biosynthesis in Arabidopsis leaf development.

  The Plant journal : for cell and molecular biology 20110201

• Subcellular localization of peptidylarginine deiminase 2 and citrullinated proteins in brains of scrapie-infected mice: nuclear localization of PAD2 and membrane fraction-enriched citrullinated proteins.

  Journal of neuropathology and experimental neurology 20110201

• The genome sequence of the leaf-cutter ant Atta cephalotes reveals insights into its obligate symbiotic lifestyle.

  PLoS genetics 20110201

• Dual mechanism of brain damage induced in vivo by the major metabolites accumulating in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome.

  Brain research 20110119

• Synergism between methamphetamine and the neuropeptide substance P on the production of nitric oxide in the striatum of mice.

  Brain research 20110119

• Reduction of N(ω)-hydroxy-L-arginine by the mitochondrial amidoxime reducing component (mARC).

  The Biochemical journal 20110115

• Effect of a single hemodialysis session on endothelial dysfunction.

  Journal of nephrology 20110101

• Effects of watermelon supplementation on aortic blood pressure and wave reflection in individuals with prehypertension: a pilot study.

  American journal of hypertension 20110101

• Dimethylarginine metabolism during acute and chronic rejection of rat renal allografts.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110101

• Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities.

  Annals of the rheumatic diseases 20110101

• Arginine is synthesized from proline, not glutamate, in enterally fed human preterm neonates.

  Pediatric research 20110101

• Nitric oxide/cGMP signaling in the corpora allata of female grasshoppers.

  Journal of insect physiology 20110101

• Etiological analysis of neurodevelopmental disabilities: single-center eight-year clinical experience in south China.

  Journal of biomedicine & biotechnology 20110101

• Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor.

  Arthritis and rheumatism 20110101

• Effects of endomorphins on human umbilical vein endothelial cells under high glucose.

  Peptides 20110101

• Enteral arginase II provides ornithine for citrulline synthesis.

  American journal of physiology. Endocrinology and metabolism 20110101

• Nitric oxide synthase inhibitors and cerebral vasospasm.

  Acta neurochirurgica. Supplement 20110101

• Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction.

  Urology 20110101

• Obesity in pregnancy: problems and potential solutions.

  Frontiers in bioscience (Elite edition) 20110101

• Identification of drought-response genes and a study of their expression during sucrose accumulation and water deficit in sugarcane culms.

  BMC plant biology 20110101

• Effect of parvoviral enteritis on plasma citrulline concentration in dogs.

  Journal of veterinary internal medicine 20110101

• Modulation of the major paths of carbon in photorespiratory mutants of synechocystis.

  PloS one 20110101

• [Deimination or citrullination, a post-translational modification with many physiological and pathophysiological facets].

  Medecine sciences : M/S 20110101

• Diagnostic properties of metabolic perturbations in rheumatoid arthritis.

  Arthritis research & therapy 20110101

• The association of dimethylarginine dimethylaminohydrolase 1 gene polymorphism with type 2 diabetes: a cohort study.

  Cardiovascular diabetology 20110101

• Recent Advances in the Pathobiology of Hodgkin's Lymphoma: Potential Impact on Diagnostic, Predictive, and Therapeutic Strategies.

  Advances in hematology 20110101

• Attenuation of brain nitrostative and oxidative damage by brain cooling during experimental traumatic brain injury.

  Journal of biomedicine & biotechnology 20110101

• Relationship between anti-CCP antibodies and oxidant and anti-oxidant activity in patients with rheumatoid arthritis.

  International journal of medical sciences 20110101

• Hyperbaric oxygen upregulates cochlear constitutive nitric oxide synthase.

  BMC neuroscience 20110101

• Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsis.

  PloS one 20110101

• New developments in the treatment of hyperammonemia: emerging use of carglumic acid.

  International journal of general medicine 20110101

• Cerebral changes occurring in arginase and dimethylarginine dimethylaminohydrolase (DDAH) in a rat model of sleeping sickness.

  PloS one 20110101

• Dose effects of chronically infused nitric oxide synthase inhibitor N(G)-nitro-L-arginine methyl ester on anabolic response and arginine metabolism in rats with subacute peritonitis.

  Biological & pharmaceutical bulletin 20110101

• Rationale and design of a proof-of-concept trial investigating the effect of uninterrupted perioperative (par)enteral nutrition on amino acid profile, cardiomyocytes structure, and cardiac perfusion and metabolism of patients undergoing coronary artery bypass grafting.

  Journal of cardiothoracic surgery 20110101

• Evidence of fibrinogen as a target of citrullination in IgM rheumatoid factor-positive polyarticular juvenile idiopathic arthritis.

  Pediatric rheumatology online journal 20110101

• [Anticitrullin antibodies--modern markers of rheumatoid arthritis].

  Terapevticheskii arkhiv 20110101

• RNA interference of argininosuccinate synthetase restores sensitivity to recombinant arginine deiminase (rADI) in resistant cancer cells.

  Journal of biomedical science 20110101

• Assessment of small bowel function in critical illness: potential role of citrulline metabolism.

  Journal of intensive care medicine 20110101

• High plasma citrulline and arginine levels ensured by sustained-release citrulline supplementation in rats.

  Nutrition (Burbank, Los Angeles County, Calif.) 20110101

• The effect of L-citrulline ingestion on ECG QT interval and autonomic nervous system activity.

  Journal of physiological anthropology 20110101

• Berberine chloride mediates its anti-leishmanial activity via differential regulation of the mitogen activated protein kinase pathway in macrophages.

  PloS one 20110101

• Parasite killing in malaria non-vector mosquito Anopheles culicifacies species B: implication of nitric oxide synthase upregulation.

  PloS one 20110101

• Argininosuccinate synthase: at the center of arginine metabolism.

  International journal of biochemistry and molecular biology 20110101

• L-lysine as adjunctive treatment in patients with schizophrenia: a single-blinded, randomized, cross-over pilot study.

  BMC medicine 20110101

• Neonatal skin maturation--vernix caseosa and free amino acids.

  Pediatric dermatology 20110101

• Systematic mutational analysis of the intracellular regions of yeast Gap1 permease.

  PloS one 20110101

• The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease.

  PloS one 20110101

• The effect of anandamide on uterine nitric oxide synthase activity depends on the presence of the blastocyst.

  PloS one 20110101

• Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the Generalized Singular Value Decomposition.

  BMC systems biology 20110101

• Relationship between time-integrated disease activity estimated by DAS28-CRP and radiographic progression of anatomical damage in patients with early rheumatoid arthritis.

  BMC musculoskeletal disorders 20110101

• NOA1 functions in a temperature-dependent manner to regulate chlorophyll biosynthesis and Rubisco formation in rice.

  PloS one 20110101

• (-)-Epigallocatechin gallate attenuates NADPH-d/nNOS expression in motor neurons of rats following peripheral nerve injury.

  BMC neuroscience 20110101

• Peripheral vascular dysfunction in chronic kidney disease.

  Cardiology research and practice 20110101

• Liver transplantation in an adult with citrullinaemia type 2.

  Journal of transplantation 20110101

• The metabolic advantage of tumor cells.

  Molecular cancer 20110101

• Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity.

  Nutrition & metabolism 20110101

• Inducible nitric oxide synthase genetic polymorphism and risk of asbestosis.

  Journal of biomedicine & biotechnology 20110101

• Effect of enhanced glycemic control with saxagliptin on endothelial nitric oxide release and CD40 levels in obese rats.

  Journal of atherosclerosis and thrombosis 20110101

• Network screening of Goto-Kakizaki rat liver microarray data during diabetic progression.

  BMC systems biology 20110101

• L-NAME treatment enhances exercise-induced content of myocardial heat shock protein 72 (Hsp72) in rats.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

• Investigating the pathogenic role of PADI4 in oesophageal cancer.

  International journal of biological sciences 20110101

• Simplivariate models: uncovering the underlying biology in functional genomics data.

  PloS one 20110101

• Shared epitope alleles remain a risk factor for anti-citrullinated proteins antibody (ACPA)--positive rheumatoid arthritis in three Asian ethnic groups.

  PloS one 20110101

• Novel multiplex technology for diagnostic characterization of rheumatoid arthritis.

  Arthritis research & therapy 20110101

• Defining the role of polyamines in colon carcinogenesis using mouse models.

  Journal of carcinogenesis 20110101

• Protein functional links in Trypanosoma brucei, identified by gene fusion analysis.

  BMC evolutionary biology 20110101

• An observational cohort study of the kynurenine to tryptophan ratio in sepsis: association with impaired immune and microvascular function.

  PloS one 20110101

• Functional role of dimerization of human peptidylarginine deiminase 4 (PAD4).

  PloS one 20110101

• Comparative genomics and transcriptomics of Propionibacterium acnes.

  PloS one 20110101

• Arginase and arginine dysregulation in asthma.

  Journal of allergy 20110101

• Arginase inhibitor in the pharmacological correction of endothelial dysfunction.

  International journal of hypertension 20110101

• Expression of constitutive nitric oxide synthase isoforms in varicose vein wall; preliminary results.

  International journal of vascular medicine 20110101

• Inhaled nitric oxide for the adjunctive therapy of severe malaria: protocol for a randomized controlled trial.

  Trials 20110101

• Effect of silibinin on endothelial dysfunction and ADMA levels in obese diabetic mice.

  Cardiovascular diabetology 20110101

• Smoking and pulmonary fibrosis: novel insights.

  Pulmonary medicine 20110101

• PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection.

  PloS one 20110101

• [Methotrexate-induced changes in the concentration of antibodies to mutaded citrullinated vimentin in blood serum of patients with rheumatoid arthritis].

  Terapevticheskii arkhiv 20110101

• Increased nitric oxide availability attenuates high fat diet metabolic alterations and gene expression associated with insulin resistance.

  Cardiovascular diabetology 20110101

• Metabolomic profiling reveals a role for androgen in activating amino acid metabolism and methylation in prostate cancer cells.

  PloS one 20110101

• Thalidomide Analogues Suppress Lipopolysaccharide-Induced Synthesis of TNF-α and Nitrite, an Intermediate of Nitric Oxide, in a Cellular Model of Inflammation.

  The open biochemistry journal 20110101

• Regulation of Inducible Nitric Oxide Synthase (iNOS) and its Potential Role in Insulin Resistance, Diabetes and Heart Failure.

  The open cardiovascular medicine journal 20110101

• [Citrullinated proteins in rheumatoid arthritis].

  Reumatologia clinica 20110101

• [Predictors of response to biologic therapies in rheumatoid arthritis].

  Reumatologia clinica 20110101

• Renal mitochondrial cytopathies.

  International journal of nephrology 20110101

• Metabolic deficiences revealed in the biotechnologically important model bacterium Escherichia coli BL21(DE3).

  PloS one 20110101

• Pancreatic β-cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis.

  PloS one 20110101

• Fatty acid binding protein 1 is related with development of aspirin-exacerbated respiratory disease.

  PloS one 20110101

• Toll-like receptor 4 is involved in inflammatory and joint destructive pathways in collagen-induced arthritis in DBA1J mice.

  PloS one 20110101

• Bothrops jararaca peptide with anti-hypertensive action normalizes endothelium dysfunction involved in physiopathology of preeclampsia.

  PloS one 20110101

• Garlic and onion attenuates vascular inflammation and oxidative stress in fructose-fed rats.

  Journal of nutrition and metabolism 20110101

• Iron restriction induces preferential down-regulation of H(2)-consuming over H(2)-evolving reactions during fermentative growth of Escherichia coli.

  BMC microbiology 20110101

• Cochlin induced TREK-1 co-expression and annexin A2 secretion: role in trabecular meshwork cell elongation and motility.

  PloS one 20110101

• 7th meeting of the Global Arthritis Research Network.

  Arthritis research & therapy 20110101

• Biological activity of CXCL8 forms generated by alternative cleavage of the signal peptide or by aminopeptidase-mediated truncation.

  PloS one 20110101

• Effects of citrulline supplementation on fatigue and exercise performance in mice.

  Journal of nutritional science and vitaminology 20110101

• A split-ubiquitin two-hybrid screen for proteins physically interacting with the yeast amino acid transceptor Gap1 and ammonium transceptor Mep2.

  PloS one 20110101

• ROS and RNS signaling in heart disorders: could antioxidant treatment be successful?

  Oxidative medicine and cellular longevity 20110101

• Plasma free amino acid profiling of five types of cancer patients and its application for early detection.

  PloS one 20110101

• A systematic review of serum biomarkers anti-cyclic citrullinated Peptide and rheumatoid factor as tests for rheumatoid arthritis.

  Autoimmune diseases 20110101

• The core components of organelle biogenesis and membrane transport in the hydrogenosomes of Trichomonas vaginalis.

  PloS one 20110101

• Nitric oxide involvement in the acrosome reaction triggered by leptin in pig sperm.

  Reproductive biology and endocrinology : RB&E 20110101

• HLA-DRB1 shared epitope genotyping using the revised classification and its association with circulating autoantibodies, acute phase reactants, cytokines and clinical indices of disease activity in a cohort of South African rheumatoid arthritis patients.

  Arthritis research & therapy 20110101

• Neurochemical architecture of the central complex related to its function in the control of grasshopper acoustic communication.

  PloS one 20110101

• Helicobacter pylori Induces Disturbances in Gastric Mucosal Akt Activation through Inducible Nitric Oxide Synthase-Dependent S-Nitrosylation: Effect of Ghrelin.

  ISRN gastroenterology 20110101

• Management of hepatic encephalopathy.

  International journal of hepatology 20110101

• Alteration of plasma glutamate and glutamine levels in children with high-functioning autism.

  PloS one 20110101

• [Circulating citrulline levels: a biomarker for intestinal functionality assessment].

  Annales de biologie clinique 20110101

• Emerging treatment options for short bowel syndrome: potential role of teduglutide.

  Clinical and experimental gastroenterology 20110101

• Pharmacological investigations of Punica granatum in glycerol-induced acute renal failure in rats.

  Indian journal of pharmacology 20110101

• The intestinal peptide transporter PEPT1 is involved in food intake regulation in mice fed a high-protein diet.

  PloS one 20110101

• The role of asymmetric dimethyl arginine and oxidant/antioxidant system in preeclampsia.

  Fetal and pediatric pathology 20110101

• Endothelial dysfunction in the apolipoprotein E-deficient mouse: insights into the influence of diet, gender and aging.

  Lipids in health and disease 20110101

• Increased excretion of c4-carnitine species after a therapeutic acetylsalicylic Acid dose: evidence for an inhibitory effect on short-chain Fatty Acid metabolism.

  ISRN pharmacology 20110101

• Features, causes and consequences of splanchnic sequestration of amino acid in old rats.

  PloS one 20110101

• Identification and characterization of genes involved in leishmania pathogenesis: the potential for drug target selection.

  Molecular biology international 20110101

• Genome economization in the endosymbiont of the wood roach Cryptocercus punctulatus due to drastic loss of amino acid synthesis capabilities.

  Genome biology and evolution 20110101

• Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis.

  Arthritis research & therapy 20110101

• Severe malarial anemia: innate immunity and pathogenesis.

  International journal of biological sciences 20110101

• ACPA (anti-citrullinated protein antibodies) and rheumatoid arthritis.

  Acta reumatologica portuguesa 20110101

• The fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA.

  Arthritis research & therapy 20110101

• Neuroinflammation and cerebrovascular disease in old age: a translational medicine perspective.

  Journal of aging research 20110101

• Fetoplacental vascular endothelial dysfunction as an early phenomenon in the programming of human adult diseases in subjects born from gestational diabetes mellitus or obesity in pregnancy.

  Experimental diabetes research 20110101

• Establishment of reference range of plasma amino acids for younger Chinese children by reverse phase HPLC.

  Journal of pediatric endocrinology & metabolism : JPEM 20110101

• Emergent role of gasotransmitters in ischemia-reperfusion injury.

  Medical gas research 20110101

• Effect of an hyperbaric nitrogen narcotic ambience on arginine and citrulline levels, the precursor and co-product of nitric oxide, in rat striatum.

  Medical gas research 20110101

• Influence of conserved and hypervariable genetic markers on genotyping circulating strains of Neisseria gonorrhoeae.

  PloS one 20110101

• Profiling the human response to physical exercise: a computational strategy for the identification and kinetic analysis of metabolic biomarkers.

  Journal of clinical bioinformatics 20110101

• PPAR-α Agonist Fenofibrate Upregulates Tetrahydrobiopterin Level through Increasing the Expression of Guanosine 5'-Triphosphate Cyclohydrolase-I in Human Umbilical Vein Endothelial Cells.

  PPAR research 20110101

• Rapid S-nitrosylation of actin by NO-generating donors and in inflammatory pain model mice.

  Molecular pain 20110101

• A metabolic index of ischemic injury for perfusion-recovery of cadaveric rat livers.

  PloS one 20110101

• Detection and quantification of citrullinated chemokines.

  PloS one 20110101

• Protein profile changes during porcine oocyte aging and effects of caffeine on protein expression patterns.

  PloS one 20110101

• Analysis of inducible nitric oxide synthase gene polymorphisms in vitiligo in Han Chinese people.

  PloS one 20110101

• Biochemistry of nitric oxide.

  Indian journal of clinical biochemistry : IJCB 20110101

• The HIV-1 transactivator factor (Tat) induces enterocyte apoptosis through a redox-mediated mechanism.

  PloS one 20110101

• Peptidyl-arginine deiminase: an additional marker of rheumatoid arthritis.

  Clinical laboratory 20110101

• Transcriptomic analysis in diabetic nephropathy of streptozotocin-induced diabetic rats.

  International journal of molecular sciences 20110101

• The synovium in rheumatoid arthritis.

  The open rheumatology journal 20110101

• Perinatal exogenous nitric oxide in fawn-hooded hypertensive rats reduces renal ribosomal biogenesis in early life.

  Frontiers in genetics 20110101

• [Role of charge and hydrophobic effects in reactions of peptide substrates and inhibitors with thrombin].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101

• [Plasma citrulline as a marker of loss of enterocitary mass in coeliac disease in childhood].

  Nutricion hospitalaria 20110101

• Metabolite profile changes in xylem sap and leaf extracts of strategy I plants in response to iron deficiency and resupply.

  Frontiers in plant science 20110101

• Peptidylarginine deiminase 2 suppresses inhibitory {kappa}B kinase activity in lipopolysaccharide-stimulated RAW 264.7 macrophages.

  The Journal of biological chemistry 20101217

• In vitro and in vivo induction and activation of nNOS by LPS in oligodendrocytes.

  Journal of neuroimmunology 20101215

• Re and Tc tricarbonyl complexes: from the suppression of NO biosynthesis in macrophages to in vivo targeting of inducible nitric oxide synthase.

  Bioconjugate chemistry 20101215

• Insulin resistance in obesity and metabolic syndrome: is there a connection with platelet l-arginine transport?

  Blood cells, molecules & diseases 20101215

• Enhancement of the citrulline-nitric oxide cycle in astroglioma cells by the proline-rich peptide-10c from Bothrops jararaca venom.

  Brain research 20101202

• Plasma citrulline as a quantitative biomarker of HIV-associated villous atrophy in a tropical enteropathy population.

  Clinical nutrition (Edinburgh, Scotland) 20101201

• Arginine metabolism in Trichomonas vaginalis infected with Mycoplasma hominis.

  Microbiology (Reading, England) 20101201

• All you wanted to know about anti-CCP but were afraid to ask.

  Autoimmunity reviews 20101201

• L-citrulline attenuates arrested alveolar growth and pulmonary hypertension in oxygen-induced lung injury in newborn rats.

  Pediatric research 20101201

• Periodontitis in RA-the citrullinated enolase connection.

  Nature reviews. Rheumatology 20101201

• Structure-activity studies of GmSubPep, a soybean peptide defense signal derived from an extracellular protease.

  Peptides 20101201

• Anti-citrullinated peptide antibody-negative RA is a genetically distinct subset: a definitive study using only bone-erosive ACPA-negative rheumatoid arthritis.

  Rheumatology (Oxford, England) 20101201

• Increased levels of citrullinated antithrombin in plasma of patients with rheumatoid arthritis and colorectal adenocarcinoma determined by a newly developed ELISA using a specific monoclonal antibody.

  Thrombosis and haemostasis 20101201

• Arginine-induced stimulation of protein synthesis and survival in IPEC-J2 cells is mediated by mTOR but not nitric oxide.

  American journal of physiology. Endocrinology and metabolism 20101201

• Assessment of metabolic phenotypes in patients with non-ischemic dilated cardiomyopathy undergoing cardiac resynchronization therapy.

  Journal of cardiovascular translational research 20101201

• The role of asymmetric dimethylarginine and arginine in the failing heart and its vasculature.

  European journal of heart failure 20101201

• Involvement of autoimmunity in the pathogenesis of aggressive periodontitis.

  Journal of dental research 20101201

• Behavioural responses of the snail Lymnaea acuminata to carbohydrates and amino acids in bait pellets.

  Annals of tropical medicine and parasitology 20101201

• Argininosuccinic aciduria: clinical and biochemical phenotype findings in Malaysian children.

  The Malaysian journal of pathology 20101201

• Effects of angiotensin type 1 receptor blockade on arginine and ADMA synthesis and metabolic pathways in fawn-hooded hypertensive rats.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101101

• An intronic enhancer driven by NF-κB contributes to transcriptional regulation of peptidylarginine deiminase type I gene in human keratinocytes.

  The Journal of investigative dermatology 20101101

• Anticitrulline antibodies can be caused by homocitrulline-containing proteins in rabbits.

  Arthritis and rheumatism 20101101

• Cancer cell sensitivity to arginine deprivation in vitro is not determined by endogenous levels of arginine metabolic enzymes.

  Cell biology international 20101101

• Polymorphic variants of genes related to arginine metabolism and the risk of orofacial clefts.

  Archives of oral biology 20101101

• Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats.

  Journal of pineal research 20101101

• No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers.

  Cephalalgia : an international journal of headache 20101101

• Transcriptome analysis of nitrate assimilation in Aspergillus nidulans reveals connections to nitric oxide metabolism.

  Molecular microbiology 20101101

• PADI4 gene polymorphism is not associated with ankylosing spondylitis in Chinese Han population.

  Scandinavian journal of immunology 20101101

• LXR deficiency confers increased protection against visceral Leishmania infection in mice.

  PLoS neglected tropical diseases 20101101

• Characterization of a nitric oxide synthase from the plant kingdom: NO generation from the green alga Ostreococcus tauri is light irradiance and growth phase dependent.

  The Plant cell 20101101

• [Therapeutic approaches for patients with adult-onset type II citrullinemia (CTLN2): effectiveness of treatment with low-carbohydrate diet and sodium pyruvate].

  Rinsho shinkeigaku = Clinical neurology 20101101

• Modulatory Role of Nitric Oxide/cGMP System in Endothelin-1-Induced Signaling Responses in Vascular Smooth Muscle Cells.

  Current cardiology reviews 20101101

• Descending serotonergic facilitation mediated by spinal 5-HT3 receptors engages spinal rapamycin-sensitive pathways in the rat.

  Neuroscience letters 20101029

• Secondary structure and solvent accessibility of a calmodulin-binding C-terminal segment of membrane-associated myelin basic protein.

  Biochemistry 20101019

• [Screening and identification of a novel ovarian specific protein in mouse].

  Zhonghua yi xue za zhi 20101012

• Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption.

  Diabetes 20101001

• HLA-DR1001 presents 'altered-self' peptides derived from joint-associated proteins by accepting citrulline in three of its binding pockets.

  Arthritis and rheumatism 20101001

• Modulation of gene expression by Polyalthia longifolia in postmenopausal women with coronary artery disease: an in vitro study.

  Journal of cardiovascular translational research 20101001

• A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts anti-inflammatory action in endothelial cells.

  Diabetologia 20101001

• A multivariate analysis of the effects of aging on glutamate, GABA and arginine metabolites in the rat vestibular nucleus.

  Hearing research 20101001

• Interstitial lung disease in rheumatoid arthritis.

  Current rheumatology reports 20101001

• Analysis of plasma citrulline and intestinal morphometry in mice with hepatosplenic schistosomiasis.

  Surgical infections 20101001

• Angiotensin-(1-7) upregulates cardiac nitric oxide synthase in spontaneously hypertensive rats.

  American journal of physiology. Heart and circulatory physiology 20101001

• MR imaging of atlantoaxial joint in early rheumatoid arthritis.

  La Radiologia medica 20101001

• Activation of the NO-ergic system of the nucleus accumbens on presentation of contextual danger signals.

  Neuroscience and behavioral physiology 20101001

• The 2009 ESPEN Sir David Cuthbertson. Citrulline: a new major signaling molecule or just another player in the pharmaconutrition game?

  Clinical nutrition (Edinburgh, Scotland) 20101001

• Analysis of the rice mitochondrial carrier family reveals anaerobic accumulation of a basic amino acid carrier involved in arginine metabolism during seed germination.

  Plant physiology 20101001

• Effect of oral arginine supplementation on exhaled nitric oxide concentration in sickle cell anemia and acute chest syndrome.

  Journal of pediatric hematology/oncology 20101001

• Elevated levels of asymmetric dimethylarginine in chronic heart failure: a pathophysiologic link between oxygen radical load and impaired vasodilator capacity and the therapeutic effect of allopurinol.

  Clinical pharmacology and therapeutics 20101001

• Comparative pharmacology of chemically distinct NADPH oxidase inhibitors.

  British journal of pharmacology 20101001

• Glutamine: precursor or nitrogen donor for citrulline synthesis?

  American journal of physiology. Endocrinology and metabolism 20101001

• Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis.

  Nature genetics 20101001

• Citrullinated peptide and its relevance to rheumatoid arthritis: an update.

  International journal of rheumatic diseases 20101001

• Diagnostic value of anti-modified citrullinated vimentin in rheumatoid arthritis.

  International journal of rheumatic diseases 20101001

• A randomised phase II study of pegylated arginine deiminase (ADI-PEG 20) in Asian advanced hepatocellular carcinoma patients.

  British journal of cancer 20100928

• Nitric oxide and cancer.

  World journal of hepatology 20100927

• Posttranslational modification of the NH2-terminal region of CXCL5 by proteases or peptidylarginine Deiminases (PAD) differently affects its biological activity.

  The Journal of biological chemistry 20100924

• Simultaneous quantitative determination of N(G),N(G)-dimethyl-L-arginine or asymmetric dimethylarginine and related pathway's metabolites in biological fluids by ultrahigh-performance liquid chromatography/electrospray ionization-tandem mass spectrometry.

  Analytica chimica acta 20100916

• L-citrulline-malate influence over branched chain amino acid utilization during exercise.

  European journal of applied physiology 20100901

• Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis.

  Arthritis and rheumatism 20100901

• Simultaneous determination of l-citrulline and l-arginine in plasma by high performance liquid chromatography.

  Clinical biochemistry 20100901

• Exploring a link between fatigue and intestinal injury during pelvic radiotherapy.

  The oncologist 20100901

• Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species.

  Arteriosclerosis, thrombosis, and vascular biology 20100901

• Recurrent liver failure in a 25-year-old female.

  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20100901

• Role of acetyl-phosphate in activation of the Rrp2-RpoN-RpoS pathway in Borrelia burgdorferi.

  PLoS pathogens 20100901

• HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus.

  PLoS pathogens 20100901

• Nitric oxide is an essential mediator for neuronal differentiation of rat primary cortical neuron cells.

  Experimental neurobiology 20100901

• In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitors.

  Journal of the American Chemical Society 20100825

• Artifacts related to N-methyl-N-(tert-butyldimethylsilyl)trifluoroacetamide derivatization of citrulline revealed by gas chromatography-mass spectrometry using both electron and chemical ionization.

  Journal of chromatography. A 20100813

• Citrullinemia type I: molecular screening of the ASS1 gene by exonic sequencing and targeted mutation analysis.

  Genetics and molecular research : GMR 20100803

• Changes in intramuscular amino acid levels in submaximally exercised horses - a pilot study.

  Journal of animal physiology and animal nutrition 20100801

• Consumption of pasteurized human lysozyme transgenic goats' milk alters serum metabolite profile in young pigs.

  Transgenic research 20100801

• Citrulline-based assessment score: first choice for measuring and monitoring intestinal failure after high-dose chemotherapy.

  Annals of oncology : official journal of the European Society for Medical Oncology 20100801

• Effects of maternal L-citrulline supplementation on renal function and blood pressure in offspring exposed to maternal caloric restriction: the impact of nitric oxide pathway.

  Nitric oxide : biology and chemistry 20100801

• A technique for the specific enrichment of citrulline-containing peptides.

  Analytical biochemistry 20100801

• Low citrulline in Leigh disease: still a biomarker of maternally inherited Leigh syndrome.

  Journal of child neurology 20100801

• Understanding the role of NOS-3 in ventilator-induced lung injury: don't take NO for an answer.

  American journal of physiology. Lung cellular and molecular physiology 20100801

• Fumaric aciduria: an overview and the first Brazilian case report.

  Journal of inherited metabolic disease 20100801

• The role of vacuolar processing enzyme (VPE) from Nicotiana benthamiana in the elicitor-triggered hypersensitive response and stomatal closure.

  Journal of experimental botany 20100801

• Transcriptional profiles of drought-responsive genes in modulating transcription signal transduction, and biochemical pathways in tomato.

  Journal of experimental botany 20100801

• Deimination stabilizes histone H2A/H2B dimers as revealed by electrospray ionization mass spectrometry.

  Journal of mass spectrometry : JMS 20100801

• Evaluation of inflammatory biomarkers associated with oxidative stress and histological assessment of low-level laser therapy in experimental myopathy.

  Lasers in surgery and medicine 20100801

• Inhibition of arginase activity ameliorates L-arginine-induced acute pancreatitis in rats.

  Pancreas 20100801

• Packed red blood cells suppress T-cell proliferation through a process involving cell-cell contact.

  The Journal of trauma 20100801

• Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes.

  Oncotarget 20100801

• Flavonoids: antioxidants against atherosclerosis.

  Nutrients 20100801

• Evidence for interaction between 5-hydroxytryptamine (serotonin) receptor 2A and MHC type II molecules in the development of rheumatoid arthritis.

  European journal of human genetics : EJHG 20100701

• Arginase is overactive in psoriatic skin.

  The British journal of dermatology 20100701

• Dysregulation of L-arginine metabolism and bioavailability associated to free plasma heme.

  American journal of physiology. Cell physiology 20100701

• Glutamine: precursor or nitrogen donor for citrulline synthesis?

  American journal of physiology. Endocrinology and metabolism 20100701

• Effect of a high-protein diet on food intake and liver metabolism during pregnancy, lactation and after weaning in mice.

  Proteomics 20100701

• Regulation of the nitrogen transfer pathway in the arbuscular mycorrhizal symbiosis: gene characterization and the coordination of expression with nitrogen flux.

  Plant physiology 20100701

• The intestinal fatty acid binding protein diagnosing gut dysfunction in acute pancreatitis: a pilot study.

  Pancreas 20100701

• The roles of NADPH-oxidase and nNOS for the increased oxidative stress and the oxygen consumption in the diabetic kidney.

  Diabetes/metabolism research and reviews 20100701

• Importance of research on peptidylarginine deiminase and citrullinated proteins in age-related disease.

  Geriatrics & gerontology international 20100701

• Piper sarmentosum increases nitric oxide production in oxidative stress: a study on human umbilical vein endothelial cells.

  Clinics (Sao Paulo, Brazil) 20100701

• Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3.

  Biochemistry 20100615

• Carbamylation-dependent activation of T cells: a novel mechanism in the pathogenesis of autoimmune arthritis.

  Journal of immunology (Baltimore, Md. : 1950) 20100615

• Peptidylarginine deiminase gene is differentially expressed in freshwater and brackish water rainbow trout.

  Molecular biology reports 20100601

• Teduglutide, a novel mucosally active analog of glucagon-like peptide-2 (GLP-2) for the treatment of moderate to severe Crohn's disease.

  Inflammatory bowel diseases 20100601

• Potential utility of full-spectrum antioxidant therapy, citrulline, and dietary nitrate in the management of sickle cell disease.

  Medical hypotheses 20100601

• Does pharmacological dose of parenteral arginine have beneficial effect in rats with sub-acute peritonitis?

  Pediatric surgery international 20100601

• Expression of neuronal nitric oxide synthase in rabbit carotid body glomus cells regulates large-conductance Ca2+-activated potassium currents.

  Journal of neurophysiology 20100601

• Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma.

  Current molecular medicine 20100601

• Correlation of anti-cyclic citrullinated antibody with hand joint erosion score in rheumatoid arthritis patients.

  The Korean journal of internal medicine 20100601

• Modulation of the arginase pathway in the context of microbial pathogenesis: a metabolic enzyme moonlighting as an immune modulator.

  PLoS pathogens 20100601

• Neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) in three Malay children.

  The Malaysian journal of pathology 20100601

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20100601

• Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression.

  Oncogene 20100527

• Activation of endothelial nitric oxide synthase by the pro-apoptotic drug embelin: Striking discrepancy between nitric oxide-mediated cyclic GMP accumulation and L-citrulline formation.

  Nitric oxide : biology and chemistry 20100515

• The role of nitric oxide in the expression of renal aquaporin 2 in a cirrhotic rat model: does an AVP-independent mechanism exist for the regulation of AQP2 expression?

  Digestive diseases and sciences 20100501

• Rhodotorula arctica sp. nov., a basidiomycetous yeast from Arctic soil.

  International journal of systematic and evolutionary microbiology 20100501

• Antibodies targeting mutated citrullinated vimentin in patients with psoriatic arthritis.

  Clinical rheumatology 20100501

• Deimination is regulated at multiple levels including auto-deimination of peptidylarginine deiminases.

  Cellular and molecular life sciences : CMLS 20100501

• Anti-citrullinated protein antibodies bind surface-expressed citrullinated Grp78 on monocyte/macrophages and stimulate tumor necrosis factor alpha production.

  Arthritis and rheumatism 20100501

• Pharmacological modulators of nitric oxide signaling and contextual fear conditioning in mice.

  Psychopharmacology 20100501

• Long-term outcome of patients with argininosuccinate lyase deficiency diagnosed by newborn screening in Austria.

  Molecular genetics and metabolism 20100501

• Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness.

  Journal of strength and conditioning research 20100501

• The role of intestinal microbiota in the development and severity of chemotherapy-induced mucositis.

  PLoS pathogens 20100501

• [Anti-cyclic citrullinated peptide antibodies and rheumatoid arthritis].

  Rinsho byori. The Japanese journal of clinical pathology 20100501

• MS analysis of rheumatoid arthritic synovial tissue identifies specific citrullination sites on fibrinogen.

  Proteomics. Clinical applications 20100501

• The Role of Asymmetric Dimethylarginine (ADMA) in Endothelial Dysfunction and Cardiovascular Disease.

  Current cardiology reviews 20100501

• Development of nitrergic neurons in the nervous system of the locust embryo.

  The Journal of comparative neurology 20100415

• Effects of neuronal nitric oxide synthase inhibition on resting and exercising hindlimb muscle blood flow in the rat.

  The Journal of physiology 20100415

• Pterin-centered radical as a mechanistic probe of the second step of nitric oxide synthase.

  Journal of the American Chemical Society 20100414

• Arginase activity in mitochondria--An interfering factor in nitric oxide synthase activity assays.

  Biochemical and biophysical research communications 20100409

• PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population.

  Annals of the rheumatic diseases 20100401

• Are anti-citrulline autoantibodies better serum markers for rheumatoid arthritis than rheumatoid factor in Thai population?

  Rheumatology international 20100401

• Increased nitric oxide stress is associated with migraine.

  Cephalalgia : an international journal of headache 20100401

• Plasma citrulline is a marker of absorptive small bowel length in patients with transient enterostomy and acute intestinal failure.

  Clinical nutrition (Edinburgh, Scotland) 20100401

• Potential of lithium to reduce aluminium-induced cytotoxic effects in rat brain.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20100401

• Coupling of the citrulline recycling to endothelial NO production.

  Molecular genetics and metabolism 20100401

• Plasma citrulline kinetics and prognostic value in critically ill patients.

  Intensive care medicine 20100401

• Possibility of the regression of atherosclerosis through the prevention of endothelial senescence by the regulation of nitric oxide and free radical scavengers.

  Geriatrics & gerontology international 20100401

• In vitro inhibition of low density lipoprotein carbamylation by vitamins, as an ameliorating atherosclerotic risk in uremic patients.

  Scandinavian journal of clinical and laboratory investigation 20100401

• Nitric oxide and oral diseases: can we talk about it?

  Cardiovascular & hematological agents in medicinal chemistry 20100401

• Glembatumumab vedotin, a conjugate of an anti-glycoprotein non-metastatic melanoma protein B mAb and monomethyl auristatin E for the treatment of melanoma and breast cancer.

  Current opinion in molecular therapeutics 20100401

• [Studies on the clinical manifestation and SLC25A13 gene mutation of Chinese patients with neonatal intrahepatic cholestasis caused by citrin deficiency].

  Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20100401

• Retinal protective effects of resveratrol via modulation of nitric oxide synthase on oxygen-induced retinopathy.

  Korean journal of ophthalmology : KJO 20100401

• Beneficial effects of probiotic and food borne yeasts on human health.

  Nutrients 20100401

• NMR-based metabonomic study of the sub-acute toxicity of titanium dioxide nanoparticles in rats after oral administration.

  Nanotechnology 20100326

• Directed evolution of an antitumor drug (arginine deiminase PpADI) for increased activity at physiological pH.

  Chembiochem : a European journal of chemical biology 20100322

• Contribution of myelin autoantigen citrullination to T cell autoaggression in the central nervous system.

  Journal of immunology (Baltimore, Md. : 1950) 20100315

• [Impact of citrullination upon antigenicity of fibrinogen].

  Zhonghua yi xue za zhi 20100309

• Role of arginine guanidinium moiety in nitric-oxide synthase mechanism of oxygen activation.

  The Journal of biological chemistry 20100305

• Plasma levels of nitric oxide related amino acids in demented subjects with Down syndrome are related to neopterin concentrations.

  Amino acids 20100301

• Developmental and age-related changes of peptidylarginine deiminase 2 in the mouse brain.

  Journal of neuroscience research 20100301

• Autoantibodies in rheumatoid arthritis: rheumatoid factors and anticitrullinated protein antibodies.

  QJM : monthly journal of the Association of Physicians 20100301

• Microbial influences on the small intestinal response to radiation injury.

  Current opinion in gastroenterology 20100301

• Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase.

  Neurochemistry international 20100301

• Effects of dl-2-hydroxy-4-methylthiobutyrate on the first-pass intestinal metabolism of dietary methionine and its extra-intestinal availability.

  The British journal of nutrition 20100301

• Magnetic circular dichroism spectroscopic characterization of the NOS-like protein from Geobacillus stearothermophilus (gsNOS).

  Journal of inorganic biochemistry 20100301

• Metabolic profiling of Arabidopsis thaliana epidermal cells.

  Journal of experimental botany 20100301

• 'Relaxers' damage hair: evidence from amino acid analysis.

  Journal of the American Academy of Dermatology 20100301

• Inhaled nitric oxide and related therapies.

  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20100301

• Inhibition of L-arginine metabolizing enzymes by L-arginine-derived advanced glycation end products.

  Journal of clinical biochemistry and nutrition 20100301

• Asymmetric Arginine dimethylation of Epstein-Barr virus nuclear antigen 2 promotes DNA targeting.

  Virology 20100220

• Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production.

  The Journal of biological chemistry 20100219

• [What is your diagnosis? Non-erosive seronegative polyarthritis].

  Praxis 20100217

• Mechanisms of nitrite reduction to nitric oxide in the heart and vessel wall.

  Nitric oxide : biology and chemistry 20100215

• Beta-actin association with endothelial nitric-oxide synthase modulates nitric oxide and superoxide generation from the enzyme.

  The Journal of biological chemistry 20100212

• Evidence for a functional role of IgE anticitrullinated protein antibodies in rheumatoid arthritis.

  Proceedings of the National Academy of Sciences of the United States of America 20100209

• Does anti-mutated citrullinated vimentin have additional value as a serological marker in the diagnostic and prognostic investigation of patients with rheumatoid arthritis? A systematic review.

  Annals of the rheumatic diseases 20100201

• Prediction of radiographic progression in rheumatoid arthritis and the role of antibodies against mutated citrullinated vimentin: results from a 10-year prospective study.

  Annals of the rheumatic diseases 20100201

• Rheumatoid arthritis, Proteus, anti-CCP antibodies and Karl Popper.

  Autoimmunity reviews 20100201

• Nitric oxide originating from NOS1 controls oxygen utilization and electrolyte transport efficiency in the diabetic kidney.

  American journal of physiology. Renal physiology 20100201

• Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells.

  Diabetes 20100201

• Involvement of peptidylarginine deiminase-mediated post-translational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease.

  Acta neuropathologica 20100201

• Neutrophil fate in gingival crevicular fluid.

  Ultrastructural pathology 20100201

• Glutamate excitotoxicity mediates neuronal apoptosis after hypothermic circulatory arrest.

  The Annals of thoracic surgery 20100201

• The assessment, and glucagon-like peptide-2 modulation, of intestinal absorption and function.

  Seminars in pediatric surgery 20100201

• Interpreting metabolomic profiles using unbiased pathway models.

  PLoS computational biology 20100201

• Pathological basis of symptoms and crises in sickle cell disorder: implications for counseling and psychotherapy.

  Hematology reports 20100126

• Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis.

  Annals of the rheumatic diseases 20100101

• Effects of alpha-ketoglutarate on neutrophil intracellular amino and alpha-keto acid profiles and ROS production.

  Amino acids 20100101

• Effect of L-arginine on metabolism of polyamines in rat's brain with extrahepatic cholestasis.

  Amino acids 20100101

• Anti-citrullinated protein/peptide autoantibodies in association with genetic and environmental factors as indicators of disease outcome in rheumatoid arthritis.

  Autoimmunity reviews 20100101

• Peptidylarginine deiminase 4 and citrullination in health and disease.

  Autoimmunity reviews 20100101

• Nitric oxide and nitric oxide synthase isoforms in the normal, hypertrophic, and failing heart.

  Molecular and cellular biochemistry 20100101

• Select nutrients and their associated transporters are increased in the ovine uterus following early progesterone administration.

  Biology of reproduction 20100101

• Arginase inhibition mediates cardioprotection during ischaemia-reperfusion.

  Cardiovascular research 20100101

• Comparison of chemiluminescence enzyme immunoassay (CLEIA) with ELISA for the determination of anti-cyclic citrullinated peptide antibodies.

  Clinica chimica acta; international journal of clinical chemistry 20100101

• Regulation of nitric oxide production in health and disease.

  Current opinion in clinical nutrition and metabolic care 20100101

• Oral L-citrulline supplementation attenuates blood pressure response to cold pressor test in young men.

  American journal of hypertension 20100101

• In vivo renal arginine release is impaired throughout development of chronic kidney disease.

  American journal of physiology. Renal physiology 20100101

• Effect of intestinal resections on arginine metabolism: practical implications for nutrition support.

  Current opinion in clinical nutrition and metabolic care 20100101

• Mechanisms of nitric oxide synthase uncoupling in endotoxin-induced acute lung injury: role of asymmetric dimethylarginine.

  Vascular pharmacology 20100101

• Effects of blockade of dopamine D2 receptors on extracellular citrulline levels in the nucleus accumbens during performance of a conditioned reflex fear response.

  Neuroscience and behavioral physiology 20100101

• A residue outside the active site CXXC motif regulates the catalytic efficiency of Glutaredoxin 3.

  Molecular bioSystems 20100101

• Rheumatoid arthritis-specific autoantibodies to peptidyl arginine deiminase type 4 inhibit citrullination of fibrinogen.

  Arthritis and rheumatism 20100101

• Response of Th17 cells to a citrullinated arthritogenic aggrecan peptide in patients with rheumatoid arthritis.

  Arthritis and rheumatism 20100101

• Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients.

  Arthritis and rheumatism 20100101

• HMG-CoA reductase inhibitor improves endothelial dysfunction in spontaneous hypertensive rats via down-regulation of caveolin-1 and activation of endothelial nitric oxide synthase.

  Journal of Korean medical science 20100101

• Levels of anti-citrullinated protein antibodies and IgM rheumatoid factor are not associated with outcome in early arthritis patients: a cohort study.

  Arthritis research & therapy 20100101

• Mice lacking thyroid hormone receptor Beta show enhanced apoptosis and delayed liver commitment for proliferation after partial hepatectomy.

  PloS one 20100101

• The anti-cyclic citrullinated peptide response in tuberculosis patients is not citrulline-dependent and sensitive to treatment.

  Arthritis research & therapy 20100101

• Anti-cyclic citrullinated peptide antibodies in juvenile idiopathic arthritis.

  Indian journal of pediatrics 20100101

• The effects of a pre-workout supplement containing caffeine, creatine, and amino acids during three weeks of high-intensity exercise on aerobic and anaerobic performance.

  Journal of the International Society of Sports Nutrition 20100101

• Cerebral and peripheral changes occurring in nitric oxide (NO) synthesis in a rat model of sleeping sickness: identification of brain iNOS expressing cells.

  PloS one 20100101

• Citrulline evaluation in bowel transplantation.

  Transplantation proceedings 20100101

• The role of apolipoprotein E in Guillain-Barré syndrome and experimental autoimmune neuritis.

  Journal of biomedicine & biotechnology 20100101

• Antibodies to citrullinated proteins: molecular interactions and arthritogenicity.

  Immunological reviews 20100101

• Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis.

  Immunological reviews 20100101

• Role of HLA class II genes in susceptibility/resistance to inflammatory arthritis: studies with humanized mice.

  Immunological reviews 20100101

• Neonatal intrahepatic cholestasis caused by citrin deficiency in two Malaysian siblings: outcome at one year of life.

  Singapore medical journal 20100101

• Inferring the ancient history of the translation machinery and genetic code via recapitulation of ribosomal subunit assembly orders.

  PloS one 20100101

• Sequence variation in DDAH1 and DDAH2 genes is strongly and additively associated with serum ADMA concentrations in individuals with type 2 diabetes.

  PloS one 20100101

• PADI4 and tumourigenesis.

  Cancer cell international 20100101

• The use of citrullinated peptides and proteins for the diagnosis of rheumatoid arthritis.

  Arthritis research & therapy 20100101

• Novel mutations underlying argininosuccinic aciduria in Saudi Arabia.

  BMC research notes 20100101

• Scorpion venom and the inflammatory response.

  Mediators of inflammation 20100101

• Arginine and antioxidant supplement on performance in elderly male cyclists: a randomized controlled trial.

  Journal of the International Society of Sports Nutrition 20100101

• Sugar alcohols, caries incidence, and remineralization of caries lesions: a literature review.

  International journal of dentistry 20100101

• [Sound signals of danger activate the nitrergic system of the medial nucleus accumbens].

  Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20100101

• Influence of HLA DRB1 alleles in the susceptibility of rheumatoid arthritis and the regulation of antibodies against citrullinated proteins and rheumatoid factor.

  Arthritis research & therapy 20100101

• Parasitic manipulation and neuroinflammation: Evidence from the system Microphallus papillorobustus (Trematoda) - Gammarus (Crustacea).

  Parasites & vectors 20100101

• Consanguinity mapping of congenital heart disease in a South Indian population.

  PloS one 20100101

• Increased concentration of two different advanced glycation end-products detected by enzyme immunoassays with new monoclonal antibodies in sera of patients with rheumatoid arthritis.

  BMC musculoskeletal disorders 20100101

• Characterisation of nitric oxide synthase in three cnidarian-dinoflagellate symbioses.

  PloS one 20100101

• Genetic background of tolerance breakdown in rheumatoid arthritis.

  Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20100101

• Molecular and biochemical features of the mitochondrial enzyme ornithine transcarbamylase: a possible new role as a signaling factor.

  Current medicinal chemistry 20100101

• Whole blood citrulline concentrations in newborns with non-syndromic oral clefts--a preliminary report.

  Asia Pacific journal of clinical nutrition 20100101

• Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis.

  BMC systems biology 20100101

• Diagnostic performances of anti-cyclic citrullinated peptide antibodies type IgM, IgA and IgG in Syrian patients with rheumatoid arthritis.

  Clinical laboratory 20100101

• Quantitative metabolomics by H-NMR and LC-MS/MS confirms altered metabolic pathways in diabetes.

  PloS one 20100101

• Angiopoietin-2 is increased in sepsis and inversely associated with nitric oxide-dependent microvascular reactivity.

  Critical care (London, England) 20100101

• [The damaging role of endogenous nitric oxide in the development of the experimental DSS-induced colitis in rats].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20100101

• [Plasma citrulline concentration--a reliable noninvasive marker of functional enterocyte mass].

  Casopis lekaru ceskych 20100101

• The T1405N carbamoyl phosphate synthetase polymorphism does not affect plasma arginine concentrations in preterm infants.

  PloS one 20100101

• Cerebrospinal fluid concentrations of functionally important amino acids and metabolic compounds in patients with mild cognitive impairment and Alzheimer's disease.

  Neuro-degenerative diseases 20100101

• Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis?

  Arthritis research & therapy 20100101

• Acute lyme infection presenting with amyopathic dermatomyositis and rapidly fatal interstitial pulmonary fibrosis: a case report.

  Journal of medical case reports 20100101

• Nitric oxide (no), citrulline - no cycle enzymes, glutamine synthetase and oxidative stress in anoxia (hypobaric hypoxia) and reperfusion in rat brain.

  International journal of medical sciences 20100101

• Characterization of a diverse secretome generated by the mouse preimplantation embryo in vitro.

  Reproductive biology and endocrinology : RB&E 20100101

• The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosis.

  Respiratory research 20100101

• GPS-SNO: computational prediction of protein S-nitrosylation sites with a modified GPS algorithm.

  PloS one 20100101

• Time course of nitric oxide synthases, nitrosative stress, and poly(ADP ribosylation) in an ovine sepsis model.

  Critical care (London, England) 20100101

• Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins.

  Arthritis research & therapy 20100101

• A specific protein-enriched enteral formula decreases cortisolemia and improves plasma albumin and amino acid concentrations in elderly patients.

  Nutrition & metabolism 20100101

• Endothelial dysfunction, inflammation, and apoptosis in diabetes mellitus.

  Mediators of inflammation 20100101

• Mobile genetic element proliferation and gene inactivation impact over the genome structure and metabolic capabilities of Sodalis glossinidius, the secondary endosymbiont of tsetse flies.

  BMC genomics 20100101

• Central tetrahydrobiopterin concentration in neurodevelopmental disorders.

  Frontiers in neuroscience 20100101

• Potential role for peptidylarginine deiminase 2 (PAD2) in citrullination of canine mammary epithelial cell histones.

  PloS one 20100101

• Selective control of amino acid metabolism by the GCN2 eIF2 kinase pathway in Saccharomyces cerevisiae.

  BMC biochemistry 20100101

• Atherosclerosis in early rheumatoid arthritis: very early endothelial activation and rapid progression of intima media thickness.

  Arthritis research & therapy 20100101

• Peptidylarginine deiminase type 2 is over expressed in the glaucomatous optic nerve.

  Molecular vision 20100101

• Prevalence of antibodies against mutated citrullinated vimentin and cyclic citrullinated peptide in children with juvenile idiopathic arthritis.

  Clinical and experimental rheumatology 20100101

• Expression of peptidylarginine deiminase type 4 in ovarian tumors.

  International journal of biological sciences 20100101

• [Possibilities of correction of rheological properties of the blood and free radical processess in patients with acute myocardial infarction combined with type 2 diabetes mellitus].

  Kardiologiia 20100101

• Three periods of one and a half decade of ischemic stroke susceptibility gene research: lessons we have learned.

  Genome medicine 20100101

• Role of nitric oxide and its metabolites as potential markers in lung cancer.

  Annals of thoracic medicine 20100101

• Effects of hydrogen sulfide on hemodynamics, inflammatory response and oxidative stress during resuscitated hemorrhagic shock in rats.

  Critical care (London, England) 20100101

• Nitric oxide is negatively correlated to pain during acute inflammation.

  Molecular pain 20100101

• The evolutionary trajectory of mitochondrial carrier family during metazoan evolution.

  BMC evolutionary biology 20100101

• Naturally occurring triggers that induce apoptosis-like programmed cell death in Plasmodium berghei ookinetes.

  PloS one 20100101

• The Role of PPARα Activation in Liver and Muscle.

  PPAR research 20100101

• Effect of recombinant human growth hormone on intestinal absorption and body composition in children with short bowel syndrome.

  JPEN. Journal of parenteral and enteral nutrition 20100101

• The effect of L-arginine and citrulline on endothelial function in patients in heart failure with preserved ejection fraction.

  Cardiology journal 20100101

• Screening for bovine leukocyte adhesion deficiency, deficiency of uridine monophosphate synthase, complex vertebral malformation, bovine citrullinaemia, and factor XI deficiency in Holstein cows reared in Turkey.

  Acta veterinaria Scandinavica 20100101

• Clostridium sticklandii, a specialist in amino acid degradation:revisiting its metabolism through its genome sequence.

  BMC genomics 20100101

• Diagnosing malabsorption in the intensive care unit.

  F1000 medicine reports 20100101

• The mechanism of (R,R) ZX-5 on increasing NO release.

  International journal of molecular sciences 20100101

• The association between rheumatoid arthritis and periodontal disease.

  Arthritis research & therapy 20100101

• Characteristic metabolism of free amino acids in cetacean plasma: cluster analysis and comparison with mice.

  PloS one 20100101

• Impact of the Staphylococcus epidermidis LytSR two-component regulatory system on murein hydrolase activity, pyruvate utilization and global transcriptional profile.

  BMC microbiology 20100101

• Insights into metazoan evolution from Alvinella pompejana cDNAs.

  BMC genomics 20100101

• Inflammatory responses in epithelia: endotoxin-induced IL-6 secretion and iNOS/NO production are differentially regulated in mouse mammary epithelial cells.

  Journal of inflammation (London, England) 20100101

• Endothelial function in migraine: a cross-sectional study.

  BMC neurology 20100101

• Antibodies to mutated citrullinated vimentin in rheumatoid arthritis: diagnostic value, association with radiological damage and axial skeleton affection.

  Clinical medicine insights. Arthritis and musculoskeletal disorders 20100101

• Unprecedented loss of ammonia assimilation capability in a urease-encoding bacterial mutualist.

  BMC genomics 20100101

• Arginase activities and global arginine bioavailability in wild-type and ApoE-deficient mice: responses to high fat and high cholesterol diets.

  PloS one 20100101

• Effect of L-arginine or L-citrulline oral supplementation on blood pressure and right ventricular function in heart failure patients with preserved ejection fraction.

  Cardiology journal 20100101

• Changes in amino acid metabolism during activation of mouse macrophage-like cell lines.

  In vivo (Athens, Greece) 20100101

• Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women.

  PloS one 20100101

• Mapping of citrullinated fibrinogen B-cell epitopes in rheumatoid arthritis by imaging surface plasmon resonance.

  Arthritis research & therapy 20100101

• Intestinal damage determines the inflammatory response and early complications in patients receiving conditioning for a stem cell transplantation.

  PloS one 20100101

• The role of tetrahydrobiopterin and dihydrobiopterin in ischemia/reperfusion injury when given at reperfusion.

  Advances in pharmacological sciences 20100101

• Early activation of wheat polyamine biosynthesis during Fusarium head blight implicates putrescine as an inducer of trichothecene mycotoxin production.

  BMC plant biology 20100101

• Helicobacter pylori eradication lowers serum asymmetric dimethylarginine levels.

  Mediators of inflammation 20100101

• Role of nitric oxide in shiga toxin-2-induced premature delivery of dead fetuses in rats.

  PloS one 20100101

• Retinal redox stress and remodeling in cardiometabolic syndrome and diabetes.

  Oxidative medicine and cellular longevity 20100101

• Detection of Viral Citrullinated Peptide Antibodies Directed Against EBV or VCP: In Early Rheumatoid Arthritis Patients of Indian Origin.

  Journal of laboratory physicians 20100101

• EBV Chronic Infections.

  Mediterranean journal of hematology and infectious diseases 20100101

• Ammonia production, excretion, toxicity, and defense in fish: a review.

  Frontiers in physiology 20100101

• Suppression by Ghrelin of Porphyromonas gingivalis-Induced Constitutive Nitric Oxide Synthase S-Nitrosylation and Apoptosis in Salivary Gland Acinar Cells.

  Journal of signal transduction 20100101

• Expression of eNOS in kidneys from hypertensive patients.

  International journal of nephrology and renovascular disease 20100101

• Loose anagen hair syndrome.

  International journal of trichology 20100101

• A Gut Feeling about GABA: Focus on GABA(B) Receptors.

  Frontiers in pharmacology 20100101

• Is tetrahydrobiopterin a therapeutic option in diabetic hypertensive patients?

  Integrated blood pressure control 20100101

• Analytical study of Kuberaksha/Kantaki Karanja Patra Churna [Caesalpinia Bonduc (L.) Roxb. leaf powder].

  Ayu 20100101

• Born-Oppenheimer ab initio QM/MM molecular dynamics simulations of the hydrolysis reaction catalyzed by protein arginine deiminase 4.

  The journal of physical chemistry. B 20091231

• Nitric oxide and endothelin after lipid apheresis - a pilot study.

  Atherosclerosis. Supplements 20091229

• Role of dimethylarginine dimethylaminohydrolases in the regulation of endothelial nitric oxide production.

  The Journal of biological chemistry 20091218

• Citrulline as a marker for chemotherapy induced mucosal barrier injury in pediatric patients.

  Pediatric blood & cancer 20091215

• Biomarkers for mucositis assessment.

  Pediatric blood & cancer 20091215

• Naphthoquinones and bioactive compounds from tobacco as modulators of neuronal nitric oxide synthase activity.

  Phytotherapy research : PTR 20091201

• Heterogeneity of microglial activation in the innate immune response in the brain.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20091201

• Role of the PRMT-DDAH-ADMA axis in the regulation of endothelial nitric oxide production.

  Pharmacological research 20091201

• Effect of peroxynitrite on endothelial L-arginine transport and metabolism.

  The international journal of biochemistry & cell biology 20091201

• Age-related changes in arginine and its metabolites in memory-associated brain structures.

  Neuroscience 20091201

• Thrombospondins in the heart: potential functions in cardiac remodeling.

  Journal of cell communication and signaling 20091201

• Citrulline dependence of anti-cyclic citrullinated peptide antibodies in systemic lupus erythematosus as a marker of deforming/erosive arthritis.

  The Journal of rheumatology 20091201

• Peptidylarginine deiminases and the pathogenesis of rheumatoid arthritis: a reflection of the involvement of transglutaminase in coeliac disease.

  European journal of internal medicine 20091201

• Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis.

  Nature genetics 20091201

• Effect of fish oils containing different amounts of EPA, DHA, and antioxidants on plasma and brain fatty acids and brain nitric oxide synthase activity in rats.

  Upsala journal of medical sciences 20091201

• [Is rheumatoid arthritis without anti-citrullinated peptide antibody a genetically distinct subset?].

  Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20091201

• Environmental pH determines citrulline and ornithine release through the arginine deiminase pathway in Lactobacillus fermentum IMDO 130101.

  International journal of food microbiology 20091115

• Regulation of protein Citrullination through p53/PADI4 network in DNA damage response.

  Cancer research 20091115

• Single crystal structural and absorption spectral characterizations of nitric oxide synthase complexed with N(omega)-hydroxy-L-arginine and diatomic ligands.

  Biochemistry 20091103

• Effect of centrophenoxine against rotenone-induced oxidative stress in an animal model of Parkinson's disease.

  Neurochemistry international 20091101

• Argininosuccinate lyase deficiency: longterm outcome of 13 patients detected by newborn screening.

  Molecular genetics and metabolism 20091101

• Evidence that the major metabolites accumulating in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome induce oxidative stress in brain of young rats.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20091101

• Dietary fish and fish oil and the risk of rheumatoid arthritis.

  Epidemiology (Cambridge, Mass.) 20091101

• Effect of citrullination on the function and conformation of antithrombin.

  The FEBS journal 20091101

• Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica.

  PLoS genetics 20091101

• Neuronal nitric oxide synthase and human vascular regulation.

  Trends in cardiovascular medicine 20091101

• Regulation of interdomain interactions by calmodulin in inducible nitric-oxide synthase.

  The Journal of biological chemistry 20091030

• Crystal structure of the hexameric catabolic ornithine transcarbamylase from Lactobacillus hilgardii: Structural insights into the oligomeric assembly and metal binding.

  Journal of molecular biology 20091023

• Blom7alpha is a novel heterogeneous nuclear ribonucleoprotein K homology domain protein involved in pre-mRNA splicing that interacts with SNEVPrp19-Pso4.

  The Journal of biological chemistry 20091016

• Protection of DFP-induced oxidative damage and neurodegeneration by antioxidants and NMDA receptor antagonist.

  Toxicology and applied pharmacology 20091015

• EPR and ENDOR characterization of the reactive intermediates in the generation of NO by cryoreduced oxy-nitric oxide synthase from Geobacillus stearothermophilus.

  Journal of the American Chemical Society 20091014

• Nitric oxide production and monoamine oxidase activity in cancer patients during interferon-alpha therapy.

  Amino acids 20091001

• The expression of PADI4 in synovium of rheumatoid arthritis.

  Rheumatology international 20091001

• Nitric oxide as an initiator of brain lesions during the development of Alzheimer disease.

  Neurotoxicity research 20091001

• Citrullination of CXCL8 increases this chemokine's ability to mobilize neutrophils into the blood circulation.

  Haematologica 20091001

• Improving adaptation to weaning: effect of intermittent suckling regimens on piglet feed intake, growth, and gut characteristics.

  Journal of animal science 20091001

• Mechanisms of catalysis and inhibition operative in the arginine deiminase from the human pathogen Giardia lamblia.

  Bioorganic chemistry 20091001

• Long-term ventilatory adaptation and ventilatory response to hypoxia in plateau pika (Ochotona curzoniae): role of nNOS and dopamine.

  American journal of physiology. Regulatory, integrative and comparative physiology 20091001

• The use of post-translationally modified peptides for detection of biomarkers of immune-mediated diseases.

  Journal of peptide science : an official publication of the European Peptide Society 20091001

• The arginine deiminase pathway of Lactobacillus fermentum IMDO 130101 responds to growth under stress conditions of both temperature and salt.

  Food microbiology 20091001

• Life on arginine for Mycoplasma hominis: clues from its minimal genome and comparison with other human urogenital mycoplasmas.

  PLoS genetics 20091001

• Chemical and functional aspects of posttranslational modification of proteins.

  Acta naturae 20091001

• Experimental evidence that ornithine and homocitrulline disrupt energy metabolism in brain of young rats.

  Brain research 20090929

• Differential regulation of neuronal and inducible nitric oxide synthase (NOS) in the spinal cord of mutant SOD1 (G93A) ALS mice.

  Biochemical and biophysical research communications 20090911

• Antibody against mutated citrullinated vimentin: a new sensitive marker in the diagnosis of rheumatoid arthritis.

  Rheumatology international 20090901

• Expression and citrullination of keratin in synovial tissue of rheumatoid arthritis.

  Rheumatology international 20090901

• Glutathione-supported arsenate reduction coupled to arsenolysis catalyzed by ornithine carbamoyl transferase.

  Toxicology and applied pharmacology 20090901

• In vivo arginine production and nitric oxide synthesis in pregnant Indian women with normal and low body mass indices.

  European journal of clinical nutrition 20090901

• Association of severe inflammatory polyarthritis in primary Sjögren's syndrome: clinical, serologic, and HLA analysis.

  The Journal of rheumatology 20090901

• Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition.

  Arteriosclerosis, thrombosis, and vascular biology 20090901

• Effects of L-citrulline oral supplementation on polymorphonuclear neutrophils oxidative burst and nitric oxide production after exercise.

  Free radical research 20090901

• L-Citrulline ameliorates chronic hypoxia-induced pulmonary hypertension in newborn piglets.

  American journal of physiology. Lung cellular and molecular physiology 20090901

• Targeted analysis of protein citrullination using chemical modification and tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20090901

• A possible mechanism for the apocynin-induced nitric oxide accumulation in plants.

  Plant signaling & behavior 20090901

• [A case of adult-onset type II citrullinemia with repeated nonconvulsive status epilepticus].

  Rinsho shinkeigaku = Clinical neurology 20090901

• Pain modulation by nitric oxide in the spinal cord.

  Frontiers in neuroscience 20090901

• Translationally controlled tumor protein is a novel heat shock protein with chaperone-like activity.

  Biochemical and biophysical research communications 20090821

• Effect of enzymatic deimination on the conformation of recombinant prion protein.

  Biochimica et biophysica acta 20090801

• NO/cGMP signalling: L: -citrulline and cGMP immunostaining in the central complex of the desert locust Schistocerca gregaria.

  Cell and tissue research 20090801

• Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli.

  Nature chemical biology 20090801

• Retinal degeneration.

  Ophthalmology 20090801

• FLORA: a novel method to predict protein function from structure in diverse superfamilies.

  PLoS computational biology 20090801

• [NO-ergic system activation in the nucleus accumbens during presentation of contextual signals of danger].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20090801

• Absence of nitric-oxide synthase in sequentially purified rat liver mitochondria.

  The Journal of biological chemistry 20090724

• Neutralizing a surface charge on the FMN subdomain increases the activity of neuronal nitric-oxide synthase by enhancing the oxygen reactivity of the enzyme heme-nitric oxide complex.

  The Journal of biological chemistry 20090717

• Inoculation of sugarcane with Pantoea sp. increases amino acid contents in shoot tissues; serine, alanine, glutamine and asparagine permit concomitantly ammonium excretion and nitrogenase activity of the bacterium.

  Journal of plant physiology 20090715

• Hypocitrullinemia in expanded newborn screening by LC-MS/MS is not a reliable marker for ornithine transcarbamylase deficiency.

  Journal of pharmaceutical and biomedical analysis 20090712

• Synthesis, hydrolysis, and skin retention of amino acid esters of alpha-tocopherol.

  Journal of pharmaceutical sciences 20090701

• Serum and urine nitric oxide levels in children with Henoch-Schonlein purpura during activity and remission: a study from North India.

  Rheumatology international 20090701

• Memory-related changes in L-citrulline and agmatine in the rat brain.

  Hippocampus 20090701

• Consequences of perinatal treatment with L-arginine and antioxidants for the renal transcriptome in spontaneously hypertensive rats.

  Pflugers Archiv : European journal of physiology 20090701

• Profile of autoantibodies in Jaccoud's arthropathy.

  Joint, bone, spine : revue du rhumatisme 20090701

• Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in salt-sensitive hypertension-induced heart failure.

  The journal of physiological sciences : JPS 20090701

• Ornithine transcarbamylase deficiency: a possible risk factor for thrombosis.

  Pediatric blood & cancer 20090701

• Muscarinic receptor-mediated nitric oxide release in a K562 erythroleukaemia cell line.

  Autonomic & autacoid pharmacology 20090701

• Organic anion transporter OAT1 is involved in renal handling of citrulline.

  American journal of physiology. Renal physiology 20090701

• A two-stage case-control association study of PADI2 with schizophrenia.

  Journal of human genetics 20090701

• The peroxisome proliferator-activated receptor-alpha (PPAR-alpha) agonist, AVE8134, attenuates the progression of heart failure and increases survival in rats.

  Acta pharmacologica Sinica 20090701

• Diagnostic and prognostic usefulness of antibodies to citrullinated peptides.

  Joint, bone, spine : revue du rhumatisme 20090701

• Dimethylarginine dimethylaminohydrolase in rat penile tissue: reduced enzyme activity is responsible for erectile dysfunction in a rat model of atherosclerosis.

  International journal of impotence research 20090701

• Arginine, citrulline and nitric oxide metabolism in sepsis.

  Clinical science (London, England : 1979) 20090602

• Diminished global arginine bioavailability and increased arginine catabolism as metabolic profile of increased cardiovascular risk.

  Journal of the American College of Cardiology 20090602

• No effect of short-term arginine supplementation on nitric oxide production, metabolism and performance in intermittent exercise in athletes.

  The Journal of nutritional biochemistry 20090601

• Neurochemical approaches in the laboratory diagnosis of Parkinson and Parkinson dementia syndromes: a review.

  CNS neuroscience & therapeutics 20090601

• Quantitative RT-PCR comparison of the urea and nitric oxide cycle gene transcripts in adult human tissues.

  Molecular genetics and metabolism 20090601

• Increased nitric oxide formation followed by increased arginase activity induces relative lack of arginine at the wound site and alters whole nutritional status in rats almost within the early healing period.

  Nitric oxide : biology and chemistry 20090601

• The somatostatin analog SOM230 (pasireotide) ameliorates injury of the intestinal mucosa and increases survival after total-body irradiation by inhibiting exocrine pancreatic secretion.

  Radiation research 20090601

• Effects of neuronal nitric oxide synthase on human coronary artery diameter and blood flow in vivo.

  Circulation 20090526

• Discovery of inducible nitric oxide synthase (iNOS) inhibitor development candidate KD7332, part 1: Identification of a novel, potent, and selective series of quinolinone iNOS dimerization inhibitors that are orally active in rodent pain models.

  Journal of medicinal chemistry 20090514

• Regulation of FMN subdomain interactions and function in neuronal nitric oxide synthase.

  Biochemistry 20090512

• Recombinant human arginase inhibits proliferation of human hepatocellular carcinoma by inducing cell cycle arrest.

  Cancer letters 20090508

• Neutral cysteine protease bleomycin hydrolase is essential for the breakdown of deiminated filaggrin into amino acids.

  The Journal of biological chemistry 20090508

• Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles.

  Annals of the rheumatic diseases 20090501

• Arginine metabolism and nutrition in growth, health and disease.

  Amino acids 20090501

• Glucocorticoid regulation of amino acid and polyamine metabolism in the small intestine.

  Amino acids 20090501

• Plasma citrulline concentration reflects enterocyte mass in children with short bowel syndrome.

  Pediatric research 20090501

• Amino acid malnutrition in patients with chronic pancreatitis and pancreatic carcinoma.

  Pancreas 20090501

• Sustaining hypercitrullinemia, hypercholesterolemia and augmented oxidative stress in Japanese children with aspartate/glutamate carrier isoform 2-citrin-deficiency even during the silent period.

  Molecular genetics and metabolism 20090501

• Identification of novel mutations in the SLC25A15 gene in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome: a clinical, molecular, and functional study.

  Human mutation 20090501

• Mucositis and non-invasive markers of small intestinal function.

  Cancer biology & therapy 20090501

• Proteomic analysis of salt-stressed tomato (Solanum lycopersicum) seedlings: effect of genotype and exogenous application of glycinebetaine.

  Journal of experimental botany 20090501

• Dopamine D1 receptors regulate the extracellular citrulline level in the nucleus accumbens during performance of a conditioned reflex fear reaction.

  Neuroscience and behavioral physiology 20090501

• Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death.

  British journal of haematology 20090501

• Retinal deimination in aging and disease.

  IUBMB life 20090501

• Relationship between serum citrulline levels and progression to parenteral nutrition independence in children with short bowel syndrome.

  Journal of pediatric surgery 20090501

• [Failure to thrive and dyslipidemia caused by citrin deficiency: a novel clinical phenotype].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20090501

• Asymmetric dimethylarginine (ADMA) and endothelial dysfunction: implications for atherogenesis.

  Clinics (Sao Paulo, Brazil) 20090501

• The impact of intracellular generation of nitric oxide on the radiation response of human tumor cells.

  Radiation research 20090501

• Adverse effects associated with arginine alpha-ketoglutarate containing supplements.

  Human & experimental toxicology 20090501

• Potent antitumor activity of the anti-CD19 auristatin antibody drug conjugate hBU12-vcMMAE against rituximab-sensitive and -resistant lymphomas.

  Blood 20090430

• Assessment of citrullinated myelin by 1H-MR spectroscopy in early-onset multiple sclerosis.

  AJNR. American journal of neuroradiology 20090401

• Effect of uncoupling endothelial nitric oxide synthase on calcium homeostasis in aged porcine endothelial cells.

  Cardiovascular research 20090401

• Neutral loss of isocyanic acid in peptide CID spectra: a novel diagnostic marker for mass spectrometric identification of protein citrullination.

  Journal of the American Society for Mass Spectrometry 20090401

• Hematologic, biochemical, and cardiopulmonary effects of L-arginine supplementation or phosphodiesterase 5 inhibition in patients with sickle cell disease who are on hydroxyurea therapy.

  European journal of haematology 20090401

• Enhanced amine and amino acid analysis using Pacific Blue and the Mars Organic Analyzer microchip capillary electrophoresis system.

  Analytical chemistry 20090401

• Altered arginine metabolism in the central nervous system (CNS) of the Cln3-/- mouse model of juvenile Batten disease.

  Neuropathology and applied neurobiology 20090401

• The effects of short intensive exercise on plasma free amino acids in standardbred trotters.

  Journal of animal physiology and animal nutrition 20090401

• Transport characteristics of L-citrulline in renal apical membrane of proximal tubular cells.

  Biopharmaceutics & drug disposition 20090401

• Over-expression of a tomato N-acetyl-L-glutamate synthase gene (SlNAGS1) in Arabidopsis thaliana results in high ornithine levels and increased tolerance in salt and drought stresses.

  Journal of experimental botany 20090401

• Systems analysis of bioenergetics and growth of the extreme halophile Halobacterium salinarum.

  PLoS computational biology 20090401

• Ask the doctor. My husband is taking arginine and citrulline supplements because he read that they will protect his heart and arteries. Should I try these supplements, too, or is this a waste of money?

  Harvard heart letter : from Harvard Medical School 20090401

• The role of nitric oxide in mycobacterial infections.

  Immune network 20090401

• [T cell proliferative response and antibody formation to citrullinated collagen type II in patients with rheumatoid arthritis].

  Zhonghua yi xue za zhi 20090317

• Physarum nitric oxide synthases: genomic structures and enzymology of recombinant proteins.

  The Biochemical journal 20090315

• Detection of arc genes related with the ethyl carbamate precursors in wine lactic acid bacteria.

  Journal of agricultural and food chemistry 20090311

• Homocysteine decreases platelet NO level via protein kinase C activation.

  Nitric oxide : biology and chemistry 20090301

• Citrullinated fibrinogen shows defects in FPA and FPB release and fibrin polymerization catalyzed by thrombin.

  Clinica chimica acta; international journal of clinical chemistry 20090301

• High-frequency detection of deletions and variable rearrangements at the ornithine transcarbamylase (OTC) locus by oligonucleotide array CGH.

  Molecular genetics and metabolism 20090301

• Detection of an L-amino acid dehydrogenase activity in Synechocystis sp. PCC 6803.

  Journal of experimental botany 20090301

• Evaluation of endogenous nitric oxide synthesis in congenital urea cycle enzyme defects.

  Metabolism: clinical and experimental 20090301

• Plasma asymmetric dimethylarginine is related to anticitrullinated protein antibodies in rheumatoid arthritis of short duration.

  Metabolism: clinical and experimental 20090301

• Initial evaluation and follow-up of acute radiation syndrome in two patients from the Dakar accident.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20090301

• Dimethylarginine dimethylaminohydrolase regulation: a novel therapeutic target in cardiovascular disease.

  Expert opinion on drug metabolism & toxicology 20090301

• Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options.

  Current neuropharmacology 20090301

• Glimepiride upregulates eNOS activity and inhibits cytokine-induced NF-kappaB activation through a phosphoinoside 3-kinase-Akt-dependent pathway.

  Diabetes, obesity & metabolism 20090201

• Post-translational modifications of chicken myelin basic protein charge components.

  Neurochemical research 20090201

• Loss of enterocyte mass is accompanied by diminished turnover of enterocytes after myeloablative therapy in haematopoietic stem-cell transplant recipients.

  Annals of oncology : official journal of the European Society for Medical Oncology 20090201

• Nitric oxide synthase and renin-angiotensin gene expression and NOS function in the postnatal renal resistance vasculature.

  Pediatric nephrology (Berlin, Germany) 20090201

• Dynamic protein methylation in chromatin biology.

  Cellular and molecular life sciences : CMLS 20090201

• A prolonged nitric oxide-dependent, opioid-mediated antinociceptive effect of hyperbaric oxygen in mice.

  The journal of pain : official journal of the American Pain Society 20090201

• Epigenetic mechanisms in mammals.

  Cellular and molecular life sciences : CMLS 20090201

• Differential impact of L-arginine deprivation on the activation and effector functions of T cells and macrophages.

  Journal of leukocyte biology 20090201

• Primary sequence, together with other factors, influence peptide deimination by peptidylarginine deiminase-4.

  Biological chemistry 20090201

• Plasma citrulline measurement using UPLC tandem mass-spectrometry to determine small intestinal enterocyte pathology.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090201

• Widespread expression of inducible NOS and citrulline in lupus nephritis tissues.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090201

• Inflammatory and oxidative stress markers in experimental crystalopathy: their modification by photostimulation.

  Photomedicine and laser surgery 20090201

• Current concepts in the pathogenesis of early rheumatoid arthritis.

  Best practice & research. Clinical rheumatology 20090201

• Selective neuronal nitric oxide synthase inhibitors and the prevention of cerebral palsy.

  Annals of neurology 20090201

• Solid-phase synthesis of cyclic peptide chitinase inhibitors: SAR of the argifin scaffold.

  Organic & biomolecular chemistry 20090121

• The second step of the nitric oxide synthase reaction: evidence for ferric-peroxo as the active oxidant.

  Journal of the American Chemical Society 20090114

• Beneficial effects of citrulline malate on skeletal muscle function in endotoxemic rat.

  European journal of pharmacology 20090105

• Identification of aquaporin 4 inhibitors using in vitro and in silico methods.

  Bioorganic & medicinal chemistry 20090101

• A new strategy for the early diagnosis of rheumatoid arthritis: a combined approach.

  Autoimmunity reviews 20090101

• Febrile mucositis in haematopoietic SCT recipients.

  Bone marrow transplantation 20090101

• Co-administration of nitric oxide (NO) donors prevents haloperidol-induced orofacial dyskinesia, oxidative damage and change in striatal dopamine levels.

  Pharmacology, biochemistry, and behavior 20090101

• Proinflammatory cytokine profiles of patients with elderly-onset rheumatoid arthritis: a comparison with younger-onset disease.

  Gerontology 20090101

• Transcriptional regulation of peptidylarginine deiminase expression in human keratinocytes.

  Journal of dermatological science 20090101

• Arginine and citrulline do not stimulate growth of two Oenococcus oeni strains in wine.

  FEMS microbiology letters 20090101

• Citrin deficiency, a perplexing global disorder.

  Molecular genetics and metabolism 20090101

• Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

  Nature chemical biology 20090101

• Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4.

  Journal of immunology (Baltimore, Md. : 1950) 20090101

• Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region.

  Arthritis and rheumatism 20090101

• Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cells.

  BMC cancer 20090101

• Autoimmune responses in the rheumatoid synovium.

  PLoS medicine 20090101

• Genotoxic responses to titanium dioxide nanoparticles and fullerene in gpt delta transgenic MEF cells.

  Particle and fibre toxicology 20090101

• From arginine methylation to ADMA: a novel mechanism with therapeutic potential in chronic lung diseases.

  BMC pulmonary medicine 20090101

• Increased PADI4 expression in blood and tissues of patients with malignant tumors.

  BMC cancer 20090101

• Arginine, scurvy and Cartier's 'tree of life'.

  Journal of ethnobiology and ethnomedicine 20090101

• The protective effects of green tea extract against L-arginine toxicity to cultured human mesangial cells.

  Journal of Korean medical science 20090101

• Identification of histone modifications in biomedical text for supporting epigenomic research.

  BMC bioinformatics 20090101

• Candidate autoantigens identified by mass spectrometry in early rheumatoid arthritis are chaperones and citrullinated glycolytic enzymes.

  Arthritis research & therapy 20090101

• Assessment of anti-cyclic citrullinated peptide in psoriatic arthritis.

  BMC research notes 20090101

• Nitric oxide synthase 2A (NOS2A) polymorphisms are not associated with invasive pneumococcal disease.

  BMC medical genetics 20090101

• Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding.

  PloS one 20090101

• High heritability of metabolomic profiles in families burdened with premature cardiovascular disease.

  Molecular systems biology 20090101

• Pegylated derivatives of recombinant human arginase (rhArg1) for sustained in vivo activity in cancer therapy: preparation, characterization and analysis of their pharmacodynamics in vivo and in vitro and action upon hepatocellular carcinoma cell (HCC).

  Cancer cell international 20090101

• Nitric oxide production by Biomphalaria glabrata haemocytes: effects of Schistosoma mansoni ESPs and regulation through the extracellular signal-regulated kinase pathway.

  Parasites & vectors 20090101

• Different properties of ACPA and IgM-RF derived from a large dataset: further evidence of two distinct autoantibody systems.

  Arthritis research & therapy 20090101

• Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis.

  Arthritis research & therapy 20090101

• A study of endothelial function and circulating asymmetric dimethylarginine levels in people with Type 1 diabetes without macrovascular disease or microalbuminuria.

  Cardiovascular diabetology 20090101

• Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice.

  BMC immunology 20090101

• Arginyl aminopeptidase-like 1 (RNPEPL1) is an alternatively processed aminopeptidase with specificity for methionine, glutamine, and citrulline residues.

  Protein and peptide letters 20090101

• Recognition of the N-terminal histone H2A and H3 peptides by peptidylarginine deiminase IV.

  Protein and peptide letters 20090101

• Suppressive properties of extracts from Japanese edible plants regarding nitric oxide generation.

  Asian Pacific journal of cancer prevention : APJCP 20090101

• Arginine deficiency augments inflammatory mediator production by airway epithelial cells in vitro.

  Respiratory research 20090101

• Recent advances on the roles of NO in cancer and chronic inflammatory disorders.

  Current medicinal chemistry 20090101

• Role of arginine in superficial wound healing in man.

  Nitric oxide : biology and chemistry 20090101

• Increased expression of PAD2 after repeated intracerebroventricular infusions of soluble Abeta(25-35) in the Alzheimer's disease model rat brain: effect of memantine.

  Cellular & molecular biology letters 20090101

• Relationship among plasma amino acids, C-reactive protein, illness severity, and outcome in critically ill dogs.

  Journal of veterinary internal medicine 20090101

• Vasodilator factors in the systemic and local adaptations to pregnancy.

  Reproductive biology and endocrinology : RB&E 20090101

• Cartilage Oligomeric Matrix Protein (COMP): A Biomarker of Arthritis.

  Biomarker insights 20090101

• Rheumatoid arthritis and smoking: putting the pieces together.

  Arthritis research & therapy 20090101

• Deregulation of hepatic insulin sensitivity induced by central lipid infusion in rats is mediated by nitric oxide.

  PloS one 20090101

• Watermelon juice: a promising feedstock supplement, diluent, and nitrogen supplement for ethanol biofuel production.

  Biotechnology for biofuels 20090101

• Role of enteral nutrition in adult short bowel syndrome undergoing intestinal rehabilitation: the long-term outcome.

  Asia Pacific journal of clinical nutrition 20090101

• Effect of non-steroidal anti-inflammatory drug etoricoxib on the hematological parameters and enzymes of colon and kidney.

  Nutricion hospitalaria 20090101

• [Oxidative stress markers in atherogenesis induced by hyperfibrinogenemia].

  Archivos de cardiologia de Mexico 20090101

• Diagnostic and prognostic value of antibodies against chimeric fibrin/filaggrin citrullinated synthetic peptides in rheumatoid arthritis.

  Arthritis research & therapy 20090101

• Sepsis-associated microvascular dysfunction measured by peripheral arterial tonometry: an observational study.

  Critical care (London, England) 20090101

• Involvement of S-nitrosylation of actin in inhibition of neurotransmitter release by nitric oxide.

  Molecular pain 20090101

• [The vicious circle that leads to rheumatoid arthritis; experimental evidence of the steps involved in this circle].

  Nederlands tijdschrift voor geneeskunde 20090101

• Nitric oxide (NO), citrulline-NO cycle enzymes, glutamine synthetase, and oxidative status in kainic acid-mediated excitotoxicity in rat brain.

  Drug and chemical toxicology 20090101

• Anticitrullinated protein/peptide antibodies and rheumatoid factors: two distinct autoantibody systems.

  Arthritis research & therapy 20090101

• Positive anti-citrullinated protein antibody status and small joint arthritis are consistent predictors of chronic disease in patients with very early arthritis: results from the NOR-VEAC cohort.

  Arthritis research & therapy 20090101

• Anti-inflammatory properties of the plant Verbascum mallophorum.

  Journal of biological regulators and homeostatic agents 20090101

• Developments in the scientific understanding of rheumatoid arthritis.

  Arthritis research & therapy 20090101

• Antibodies to mutated citrullinated vimentin and antibodies to cyclic citrullinated peptides in juvenile idiopathic arthritis.

  Clinical chemistry and laboratory medicine 20090101

• Lessons from animal models of arthritis over the past decade.

  Arthritis research & therapy 20090101

• Protein biomarkers for radiation exposure: towards a proteomic approach as a new investigation tool.

  Annali dell'Istituto superiore di sanita 20090101

• Exhaled nitric oxide in diagnosis and management of respiratory diseases.

  Annals of thoracic medicine 20090101

• The role of exercise on L-arginine nitric oxide pathway in chronic heart failure.

  The open biochemistry journal 20090101

• A Selective Role for alpha3 Subunit Glycine Receptors in Inflammatory Pain.

  Frontiers in molecular neuroscience 20090101

• [Rheumatoid arthritis (updated Current Care guideline)].

  Duodecim; laaketieteellinen aikakauskirja 20090101

• Ex-vivo changes in amino acid concentrations from blood stored at room temperature or on ice: implications for arginine and taurine measurements.

  BMC clinical pathology 20090101

• Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies.

  BMC infectious diseases 20090101

• Focus on collagen: in vitro systems to study fibrogenesis and antifibrosis state of the art.

  Fibrogenesis & tissue repair 20090101

• Level of nitrated proteins in the plasma, platelets and liver of patients with liver cirrhosis.

  Redox report : communications in free radical research 20090101

• Estradiol stimulates vasodilatory and metabolic pathways in cultured human endothelial cells.

  PloS one 20090101

• Molecular Typing of Neisseria gonorrhoeae Isolates by Opa-Typing and Ribotyping in New Delhi, India.

  International journal of microbiology 20090101

• Evaluating epistatic interaction signals in complex traits using quantitative traits.

  BMC proceedings 20090101

• Functional genomics of pH homeostasis in Corynebacterium glutamicum revealed novel links between pH response, oxidative stress, iron homeostasis and methionine synthesis.

  BMC genomics 20090101

• SP-D counteracts GM-CSF-mediated increase of granuloma formation by alveolar macrophages in lysinuric protein intolerance.

  Orphanet journal of rare diseases 20090101

• A novel platelet activating factor receptor antagonist reduces cell infiltration and expression of inflammatory mediators in mice exposed to desiccating conditions after PRK.

  Clinical & developmental immunology 20090101

• Nitric oxide and coronary vascular endothelium adaptations in hypertension.

  Vascular health and risk management 20090101

• Citrullinated antigens as C1q-binding and monoclonal rheumatoid factor (mRF)-binding peptides in synovial fluids from rheumatoid arthritis patients.

  Clinical and experimental rheumatology 20090101

• The Locust Standard Brain: A 3D Standard of the Central Complex as a Platform for Neural Network Analysis.

  Frontiers in systems neuroscience 20090101

• Regulation of extracellular chromatin release from neutrophils.

  Journal of innate immunity 20090101

• Estimation of nitric oxide as an inflammatory marker in periodontitis.

  Journal of Indian Society of Periodontology 20090101

• Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease.

  Journal of medicinal chemistry 20081225

• Reduced citrulline availability by OTC deficiency in mice is related to reduced nitric oxide production.

  American journal of physiology. Endocrinology and metabolism 20081201

• Citrulline and intestinal fatty acid-binding protein: longitudinal markers of postweaning small intestinal function in pigs?

  Journal of animal science 20081201

• Novel suppressors of alpha-synuclein toxicity identified using yeast.

  Human molecular genetics 20081201

• Mechanisms and kinetics of citrulline uptake in a model of human intestinal epithelial cells.

  Clinical nutrition (Edinburgh, Scotland) 20081201

• [New autoanti-bodies in rheumatoid arthritis: anti-citrullinated protein or peptide autoanti-bodies and the others].

  Presse medicale (Paris, France : 1983) 20081201

• Treatment of a citrin-deficient patient at the early stage of adult-onset type II citrullinaemia with arginine and sodium pyruvate.

  Journal of inherited metabolic disease 20081201

• Chronic binge ethanol-mediated acidemia reduces availability of glutamine and related amino acids in maternal plasma of pregnant sheep.

  Alcohol (Fayetteville, N.Y.) 20081201

• Dysfunctional regulation of ocular blood flow: A risk factor for glaucoma?

  Clinical ophthalmology (Auckland, N.Z.) 20081201

• Peripheral amino Acid levels in schizophrenia and antipsychotic treatment.

  Psychiatry investigation 20081201

• Autoinhibition of endothelial nitric oxide synthase (eNOS) in gut smooth muscle by nitric oxide.

  Regulatory peptides 20081129

• Substrate-ligand interactions in Geobacillus stearothermophilus nitric oxide synthase.

  Biochemistry 20081125

• The role of molecular testing and enzyme analysis in the management of hypomorphic citrullinemia.

  American journal of medical genetics. Part A 20081115

• Neuropeptidomics of the supraoptic rat nucleus.

  Journal of proteome research 20081107

• Dietary supplementation with cholesterol and docosahexaenoic acid increases the activity of the arginine-nitric oxide pathway in tissues of young pigs.

  Nitric oxide : biology and chemistry 20081101

• Lateralization of hippocampal nitric oxide mediator system in people with Alzheimer disease, multi-infarct dementia and schizophrenia.

  Neurochemistry international 20081101

• Enteral feeding induces diet-dependent mucosal dysfunction, bacterial proliferation, and necrotizing enterocolitis in preterm pigs on parenteral nutrition.

  American journal of physiology. Gastrointestinal and liver physiology 20081101

• Phenotypic variability among patients with hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome homozygous for the delF188 mutation in SLC25A15.

  Journal of medical genetics 20081101

• Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase.

  International journal of cancer 20081015

• Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes.

  The Journal of biological chemistry 20081003

• Regulation of ornithine aminotransferase gene expression and activity by all-transretinoic acid in Caco-2 intestinal epithelial cells.

  The Journal of nutritional biochemistry 20081001

• Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells.

  Annals of the rheumatic diseases 20081001

• Investigation of citrullinemia type I variants by in vitro expression studies.

  Human mutation 20081001

• Recombinant arginine deiminase reduces inducible nitric oxide synthase iNOS-mediated neurotoxicity in a coculture of neurons and microglia.

  Journal of neuroscience research 20081001

• Alterations of the arginine metabolome in asthma.

  American journal of respiratory and critical care medicine 20081001

• Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation.

  Blood 20081001

• Accumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapie-infected mice: a possible role in pathogenesis.

  The American journal of pathology 20081001

• Co-ordinated expression of amino acid metabolism in response to N and S deficiency during wheat grain filling.

  Journal of experimental botany 20081001

• Novel peptide linkers for highly potent antibody-auristatin conjugate.

  Bioconjugate chemistry 20081001

• Effect of nitrous oxide anesthesia on plasma homocysteine and endothelial function.

  Anesthesiology 20081001

• Antibodies to citrullinated alpha-enolase peptide 1 are specific for rheumatoid arthritis and cross-react with bacterial enolase.

  Arthritis and rheumatism 20081001

• An intriguing relationship between the immune response to citrullinated vimentin and the HLA shared epitope: comment on the article by Verpoort et al.

  Arthritis and rheumatism 20081001

• Arginine metabolites in wound fluids from pressure ulcers: a pilot study.

  Biological research for nursing 20081001

• Chronic low-dose L-NAME treatment effect on cardiovascular system of borderline hypertensive rats: feedback regulation?

  Neuro endocrinology letters 20081001

• Letter by Stuehlinger et al regarding article, 'Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction'.

  Circulation 20080902

• Impairment of arginine metabolism in rats after massive intestinal resection: effect of parenteral nutrition supplemented with citrulline compared with arginine.

  Clinical science (London, England : 1979) 20080901

• Is serum citrulline measurement clinically useful in coeliac disease?

  Internal and emergency medicine 20080901

• Prevalence and significance of antibodies to citrullinated human papilloma virus-47 E2345-362 in rheumatoid arthritis.

  Journal of autoimmunity 20080901

• 'O', erythropoietin carbamoylation versus carbamylation.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080901

• Citrullinated fibrinogen inhibits thrombin-catalysed fibrin polymerization.

  Journal of biochemistry 20080901

• Exercise training improves peripheral chemoreflex function in heart failure rabbits.

  Journal of applied physiology (Bethesda, Md. : 1985) 20080901

• Bacteraemia coincides with low citrulline concentrations after high-dose melphalan in autologous HSCT recipients.

  Bone marrow transplantation 20080901

• Arginine deiminase has multiple regulatory roles in the biology of Giardia lamblia.

  Journal of cell science 20080901

• Permanent intestinal failure.

  Indian pediatrics 20080901

• Cellular and biochemical actions of melatonin which protect against free radicals: role in neurodegenerative disorders.

  Current neuropharmacology 20080901

• Acute fatal presentation of ornithine transcarbamylase deficiency in a previously healthy male.

  Hepatology international 20080901

• L-arginine uptake in normal and diabetic rat retina and retinal pigment epithelium.

  Neurochemical research 20080801

• Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility.

  Human molecular genetics 20080801

• Arginases I and II in lungs of ovalbumin-sensitized mice exposed to ovalbumin: sources and consequences.

  Toxicology and applied pharmacology 20080801

• Arginase blockade protects against hepatic damage in warm ischemia-reperfusion.

  Nitric oxide : biology and chemistry 20080801

• Phosphorylation-dependent interaction of tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein (YWHA) with PADI6 following oocyte maturation in mice.

  Biology of reproduction 20080801

• Dopamine D1 receptor-dependent regulation of extracellular citrulline level in the rat nucleus accumbens during conditioned fear response.

  Neuroscience letters 20080801

• Cross-sectional multicenter study of patients with urea cycle disorders in the United States.

  Molecular genetics and metabolism 20080801

• Suppression of grasshopper sound production by nitric oxide-releasing neurons of the central complex.

  Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20080801

• Adaptation to a long term (4 weeks) arginine- and precursor (glutamate, proline and aspartate)-free diet.

  Clinical nutrition (Edinburgh, Scotland) 20080801

• Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis.

  Arthritis and rheumatism 20080801

• [Diagnostic value of antibodies to modified citrullinized vimentin in early rheumatoid arthritis].

  Klinicheskaia laboratornaia diagnostika 20080801

• Effects of microalgae Chlorella species crude extracts on intestinal adaptation in experimental short bowel syndrome.

  World journal of gastroenterology 20080728

• Arginine therapy of transgenic-knockout sickle mice improves microvascular function by reducing non-nitric oxide vasodilators, hemolysis, and oxidative stress.

  American journal of physiology. Heart and circulatory physiology 20080701

• Interorgan synthesis of arginine is down-regulated in tumor-bearing mice undergoing surgical trauma.

  Metabolism: clinical and experimental 20080701

• Pharmacologic suppression of oxidative damage and dendritic degeneration following kainic acid-induced excitotoxicity in mouse cerebrum.

  Neurotoxicology 20080701

• Detection of citrullinated proteins in synovial fluids derived from patients with rheumatoid arthritis by proteomics-based analysis.

  Annals of clinical biochemistry 20080701

• A new severe acute necrotizing pancreatitis model induced by L-ornithine in rats.

  Critical care medicine 20080701

• Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease?

  Autoimmunity reviews 20080701

• Polyaspartoyl.l-arginine inhibits platelet aggregation through stimulation of NO release from endothelial cells.

  European journal of pharmacology 20080624

• Increase in brain tumor permeability in glioma-bearing rats with nitric oxide donors.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080615

• Serum amino acid profile in patients with acute pancreatitis.

  Amino acids 20080601

• The citrulline generation test: proposal for a new enterocyte function test.

  Alimentary pharmacology & therapeutics 20080601

• Neuronal nitric oxide synthase signaling within cardiac myocytes targets phospholamban.

  American journal of physiology. Cell physiology 20080601

• Effect of chronic inhibition of converting enzyme on proximal tubule acidification.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080601

• Citrulline as a biomarker of intestinal failure due to enterocyte mass reduction.

  Clinical nutrition (Edinburgh, Scotland) 20080601

• Pathogenesis of autoimmune diseases: antibodies against transglutaminase, peptidylarginine deiminase and protein-bound citrulline in primary Sjögren's syndrome, multiple sclerosis and Alzheimer's disease.

  Scandinavian journal of immunology 20080601

• The 2007 ESPEN Sir David Cuthbertson Lecture: amino acids between and within organs. The glutamate-glutamine-citrulline-arginine pathway.

  Clinical nutrition (Edinburgh, Scotland) 20080601

• Changes in mitochondrial functionality and calcium uptake in hypertensive rats as a function of age.

  Mitochondrion 20080601

• [SLC25A13 gene mutations in Chinese infants with intrahepatic cholestasis and abnormal blood amino acids].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20080601

• Glutamatergic regulation of extracellular citrulline levels in the nucleus accumbens during an emotional conditioned reflex.

  Neuroscience and behavioral physiology 20080601

• Resveratrol in prevention and treatment of common clinical conditions of aging.

  Clinical interventions in aging 20080601

• [The diagnostic accuracy of anti-citrulline antibody assessment in the diagnosis of patients suspected of rheumatoid arthritis by a general practitioner].

  Nederlands tijdschrift voor geneeskunde 20080524

• [The diagnostic accuracy of anti-citrulline antibody assessment in the diagnosis of patients suspected of rheumatoid arthritis by a general practitioner].

  Nederlands tijdschrift voor geneeskunde 20080524

• Mutagenesis studies of substrate recognition and catalysis in the sortase A transpeptidase from Staphylococcus aureus.

  The Journal of biological chemistry 20080523

• Arginine homeostasis in allergic asthma.

  European journal of pharmacology 20080513

• Application of the Phenomenex EZ:faasttrade mark amino acid analysis kit for rapid gas-chromatographic determination of concentrations of plasma tryptophan and its brain uptake competitors.

  Amino acids 20080501

• Obesity reduces the bioavailability of nitric oxide in juveniles.

  International journal of obesity (2005) 20080501

• Histone modifications and chromatin dynamics: a focus on filamentous fungi.

  FEMS microbiology reviews 20080501

• Can biological markers act as non-invasive, sensitive indicators of radiation-induced effects in the gastrointestinal mucosa?

  Alimentary pharmacology & therapeutics 20080501

• Synovial detection and autoantibody reactivity of processed citrullinated isoforms of vimentin in inflammatory arthritides.

  Rheumatology (Oxford, England) 20080501

• Complement receptor CR2/CR1 deficiency protects mice from collagen-induced arthritis and associates with reduced autoantibodies to type II collagen and citrullinated antigens.

  Molecular immunology 20080501

• Postchemotherapy hyperammonemic encephalopathy emulating ornithine transcarbamoylase (OTC) deficiency.

  Southern medical journal 20080501

• Increased plasma glutamate, glycine, and arginine levels in complex regional pain syndrome type 1.

  Acta anaesthesiologica Scandinavica 20080501

• New biological indicators to evaluate and monitor radiation-induced damage: an accident case report.

  Radiation research 20080501

• Arginine deiminase enhances MCF-7 cell radiosensitivity by inducing changes in the expression of cell cycle-related proteins.

  Molecules and cells 20080430

• The electrostatic driving force for nucleophilic catalysis in L-arginine deiminase: a combined experimental and theoretical study.

  Biochemistry 20080422

• Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo.

  Circulation 20080415

• Dose-ranging effects of citrulline administration on plasma amino acids and hormonal patterns in healthy subjects: the Citrudose pharmacokinetic study.

  The British journal of nutrition 20080401

• Methylglyoxal and methylglyoxal-arginine adducts do not directly inhibit endothelial nitric oxide synthase.

  Annals of the New York Academy of Sciences 20080401

• Higher biomass accumulation by increasing phosphoribosylpyrophosphate synthetase activity in Arabidopsis thaliana and Nicotiana tabacum.

  Plant biotechnology journal 20080401

• Myelin localization of peptidylarginine deiminases 2 and 4: comparison of PAD2 and PAD4 activities.

  Laboratory investigation; a journal of technical methods and pathology 20080401

• Renal nerves and nNOS: roles in natriuresis of acute isovolumetric sodium loading in conscious rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080401

• Determination of citrulline in human plasma, red blood cells and urine by electron impact (EI) ionization gas chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080401

• Metabolic activation of the antitumor drug 5-(Aziridin-1-yl)-2,4-dinitrobenzamide (CB1954) by NO synthases.

  Chemical research in toxicology 20080401

• Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease.

  PLoS genetics 20080401

• [D1 dopamine receptors regulate citrulline extracellular level in the nucleus accumbens during expression of conditioned fear response].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20080401

• A density functional theory investigation on the mechanism of the second half-reaction of nitric oxide synthase.

  Journal of the American Chemical Society 20080319

• Genetic findings in Parkinson's disease and translation into treatment: a leading role for mitochondria?

  Genes, brain, and behavior 20080301

• Crucial roles of MZF1 and Sp1 in the transcriptional regulation of the peptidylarginine deiminase type I gene (PADI1) in human keratinocytes.

  The Journal of investigative dermatology 20080301

• Requirement for Mesorhizobium loti ornithine transcarbamoylase for successful symbiosis with Lotus japonicus as revealed by an unexpected long-range genome deletion.

  Plant & cell physiology 20080301

• Development of peptide-targeted lipoplexes to CXCR4-expressing rat glioma cells and rat proliferating endothelial cells.

  Molecular therapy : the journal of the American Society of Gene Therapy 20080301

• Structure of human argininosuccinate synthetase.

  Acta crystallographica. Section D, Biological crystallography 20080301

• [The roles of caveolin-1 and endothelial nitric oxide synthase in the development of portal hypertension in rats with liver cirrhosis].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20080301

• Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling.

  PLoS genetics 20080301

• Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome (HHH) presenting with acute fulminant hepatic failure.

  Journal of pediatric gastroenterology and nutrition 20080301

• Nitric oxide in plants: production and cross-talk with Ca2+ signaling.

  Molecular plant 20080301

• Specific citrullination causes assembly of a globular S100A3 homotetramer: a putative Ca2+ modulator matures human hair cuticle.

  The Journal of biological chemistry 20080222

• Inactivation of microbial arginine deiminases by L-canavanine.

  Journal of the American Chemical Society 20080213

• Interferon-gamma regulates chemokine expression and release in the human mast cell line HMC1: role of nitric oxide.

  Immunology 20080201

• Demographic and nutritional factors associated with prolonged cholestatic jaundice in the premature infant.

  Journal of perinatology : official journal of the California Perinatal Association 20080201

• Synthetic approaches to N(delta)-methylated L-arginine, N(omega)-hydroxy-L-arginine, L-citrulline, and N(delta)-cyano-L-ornithine.

  The Journal of organic chemistry 20080201

• Diagnosis of rheumatoid arthritis: multivariate analysis of biomarkers.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20080201

• Histone deimination as a response to inflammatory stimuli in neutrophils.

  Journal of immunology (Baltimore, Md. : 1950) 20080201

• Gene transfer of endothelial nitric oxide synthase attenuates flow-induced pulmonary hypertension in rabbits.

  The Annals of thoracic surgery 20080201

• Association of the HLA-DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritis.

  Arthritis and rheumatism 20080201

• [A case of adult-onset type II citrullinemia having a liver histology of nonalcoholic steatohepatitis (NASH)].

  Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20080201

• L-arginine plasma levels and severity of idiopathic pulmonary arterial hypertension.

  VASA. Zeitschrift fur Gefasskrankheiten 20080201

• Endothelial effects of antihypertensive treatment: focus on irbesartan.

  Vascular health and risk management 20080201

• The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism.

  Journal of molecular biology 20080125

• Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome with stroke-like imaging presentation: clinical, biochemical and molecular analysis.

  Journal of the neurological sciences 20080115

• [The anticitrulline antibody test: unsuitable for screening for rheumatoid arthritis].

  Nederlands tijdschrift voor geneeskunde 20080112

• [The diagnostic accuracy of anti-citrullin antibody assessment in the diagnosis of patients suspected of rheumatoid arthritis by a general practitioner].

  Nederlands tijdschrift voor geneeskunde 20080112

• Oxygen-induced radical intermediates in the nNOS oxygenase domain regulated by L-arginine, tetrahydrobiopterin, and thiol.

  Biochemistry 20080108

• Diabetes-induced coronary vascular dysfunction involves increased arginase activity.

  Circulation research 20080104

• Hypertension in spontaneously hypertensive rats occurs despite low plasma levels of homocysteine.

  Physiological research 20080101

• Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.

  British journal of clinical pharmacology 20080101

• Nitric oxide synthase in critically ischaemic muscle and alterations in isoform expression during revascularization surgery.

  The British journal of surgery 20080101

• Localization and thiol dependancy of endogenous nitro compounds-mediating urethral photo-relaxation.

  Pflugers Archiv : European journal of physiology 20080101

• Reduced nitric oxide in diabetic kidneys due to increased hepatic arginine metabolism: implications for renomedullary oxygen availability.

  American journal of physiology. Renal physiology 20080101

• Expression pattern of peptidylarginine deiminase in rat and human Schwann cells.

  Developmental neurobiology 20080101

• Renoprotective effects of neuronal NOS-derived nitric oxide and cyclooxygenase-2 metabolites in transgenic rats with inducible malignant hypertension.

  American journal of physiology. Renal physiology 20080101

• Tuning adenosine A1 and A2A receptors activation mediates L-citrulline-induced inhibition of [3H]-acetylcholine release depending on nerve stimulation pattern.

  Neurochemistry international 20080101

• Detrimental effect of oxidized LDL on endothelial arginine metabolism and transportation.

  The international journal of biochemistry & cell biology 20080101

• L-arginine metabolism in dog kidney and isolated nephron segments.

  Metabolism: clinical and experimental 20080101

• Associations of erosive arthritis with anti-cyclic citrullinated peptide antibodies and MHC Class II alleles in systemic lupus erythematosus.

  The Journal of rheumatology 20080101

• Antibodies against citrullinated vimentin in rheumatoid arthritis: higher sensitivity and extended prognostic value concerning future radiographic progression as compared with antibodies against cyclic citrullinated peptides.

  Arthritis and rheumatism 20080101

• Immunity to citrullinated proteins in rheumatoid arthritis.

  Annual review of immunology 20080101

• Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model.

  Molecular systems biology 20080101

• Antibodies to mutated citrullinated vimentin and disease activity score in early arthritis: a cohort study.

  Arthritis research & therapy 20080101

• Temporal transcriptomic analysis of the Listeria monocytogenes EGD-e sigmaB regulon.

  BMC microbiology 20080101

• Effect of prolonged intravenous glucose and essential amino acid infusion on nitrogen balance, muscle protein degradation and ubiquitin-conjugating enzyme gene expression in calves.

  Nutrition & metabolism 20080101

• Effects of nitric oxide on red blood cell development and phenotype.

  Current topics in developmental biology 20080101

• Reconstruction and analysis of the genetic and metabolic regulatory networks of the central metabolism of Bacillus subtilis.

  BMC systems biology 20080101

• A high serum level of eotaxin (CCL 11) is associated with less radiographic progression in early rheumatoid arthritis patients.

  Arthritis research & therapy 20080101

• Diagnostic utility of anti-cyclic citrullinated peptide and anti-modified citrullinated vimentin antibodies in rheumatoid arthritis.

  Protein and peptide letters 20080101

• Nitric oxide antagonizes the acid tolerance response that protects Salmonella against innate gastric defenses.

  PloS one 20080101

• Recent developments in the immunobiology of rheumatoid arthritis.

  Arthritis research & therapy 20080101

• Advances in the genetics of rheumatoid arthritis point to subclassification into distinct disease subsets.

  Arthritis research & therapy 20080101

• Inactivation of [Fe-S] metalloproteins mediates nitric oxide-dependent killing of Burkholderia mallei.

  PloS one 20080101

• Effect of nonsteroidal anti-inflammatory drugs and the procarcinogen 1,2-dimethylhydrazine on the antioxidant defense system.

  International journal of toxicology 20080101

• Ornithine-delta-aminotransferase is essential for arginine catabolism but not for proline biosynthesis.

  BMC plant biology 20080101

• Analysis of citrulline, arginine, and methylarginines using high-performance liquid chromatography.

  Methods in enzymology 20080101

• Fasting plasma citrulline concentrations do not reflect intestinal absorption capacity.

  JPEN. Journal of parenteral and enteral nutrition 20080101

• Anti-cyclic citrullinated peptide antibodies in primary Sjögren syndrome may be associated with non-erosive synovitis.

  Arthritis research & therapy 20080101

• Arginine deprivation as a targeted therapy for cancer.

  Current pharmaceutical design 20080101

• Palmitate-induced beta-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms.

  PloS one 20080101

• Excessive islet NO generation in type 2 diabetic GK rats coincides with abnormal hormone secretion and is counteracted by GLP-1.

  PloS one 20080101

• Characterization of Bacillus anthracis arginase: effects of pH, temperature, and cell viability on metal preference.

  BMC biochemistry 20080101

• The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.

  BMC genomics 20080101

• Antioxidative effects of nonsteroidal anti-inflammatory drugs during the initiation stages of experimental colon carcinogenesis in rats.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20080101

• The hidden universal distribution of amino acid biosynthetic networks: a genomic perspective on their origins and evolution.

  Genome biology 20080101

• Effect of citrulline and glutamine on nitric oxide production in RAW 264.7 cells in an arginine-depleted environment.

  JPEN. Journal of parenteral and enteral nutrition 20080101

• Pro- and anti-inflammatory cytokines release in mice injected with Crotalus durissus terrificus venom.

  Mediators of inflammation 20080101

• Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model.

  Molecular systems biology 20080101

• Induction of apoptosis by epigallocatechin gallate and autophagy inhibitors in a mouse macrophage-like cell line.

  Anticancer research 20080101

• Citrullination: the loss of tolerance and development of autoimmunity in rheumatoid arthritis.

  Reumatismo 20080101

• Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity.

  Molecular systems biology 20080101

• Possible indirect detection of rHuEPO administration in human urine by high-performance liquid chromatography tandem mass spectrometry.

  European journal of mass spectrometry (Chichester, England) 20080101

• Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis.

  Arthritis research & therapy 20080101

• An extension of the coevolution theory of the origin of the genetic code.

  Biology direct 20080101

• Inversion of allosteric effect of arginine on N-acetylglutamate synthase, a molecular marker for evolution of tetrapods.

  BMC biochemistry 20080101

• Breath alcohol level and plasma amino acids: a comparison between older and younger chronic alcohol-dependent patients.

  Alcohol and alcoholism (Oxford, Oxfordshire) 20080101

• Effect of arginase II on L-arginine depletion and cell growth in murine cell lines of renal cell carcinoma.

  Journal of hematology & oncology 20080101

• Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination.

  Arthritis research & therapy 20080101

• An important step towards completing the rheumatoid arthritis cycle.

  Arthritis research & therapy 20080101

• Measurement of nutrition status in Crohn's disease patients receiving infliximab therapy.

  Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 20080101

• Long-range enhancer associated with chromatin looping allows AP-1 regulation of the peptidylarginine deiminase 3 gene in differentiated keratinocyte.

  PloS one 20080101

• Diagnostic performance and predictive value of rheumatoid factor, anti-cyclic-citrullinated peptide antibodies and HLA-DRB1 locus genes in rheumatoid arthritis.

  International archives of medicine 20080101

• The prince and the pauper. A tale of anticancer targeted agents.

  Molecular cancer 20080101

• Nitrergic response to cyclophosphamide treatment in blood and bone marrow.

  The open biochemistry journal 20080101

• Impact of the L-arginine-Nitric Oxide Pathway and Oxidative Stress on the Pathogenesis of the Metabolic Syndrome.

  The open biochemistry journal 20080101

• The prominent role of the liver in the elimination of asymmetric dimethylarginine (ADMA) and the consequences of impaired hepatic function.

  JPEN. Journal of parenteral and enteral nutrition 20080101

• [Critical value of citrulline for complications of intestinal transplant graft].

  Revista da Associacao Medica Brasileira (1992) 20080101

• Citrulline blood levels as indicators of residual intestinal absorption in patients with short bowel syndrome.

  Annals of nutrition & metabolism 20080101

• The human neonatal small intestine has the potential for arginine synthesis; developmental changes in the expression of arginine-synthesizing and -catabolizing enzymes.

  BMC developmental biology 20080101

• [Effect of D2 dopamine receptor blockade on extracellular citrulline levels in the nucleus accumbens during expression of conditioned fear response].

  Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20080101

• T cells in rheumatoid arthritis.

  Arthritis research & therapy 20080101

• Exercise training enhanced myocardial endothelial nitric oxide synthase (eNOS) function in diabetic Goto-Kakizaki (GK) rats.

  Cardiovascular diabetology 20080101

• Role of nitric oxide synthase in insect cell radioresistance: an in-silico analysis.

  Bioinformation 20080101

• The role of polyamines in protein-dependent hypoxic tolerance of Drosophila.

  BMC physiology 20080101

• Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab therapy.

  Arthritis research & therapy 20080101

• Epitope spreading in animal models: array of hope in rheumatoid arthritis and multiple sclerosis.

  Arthritis research & therapy 20080101

• Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system.

  Disease models & mechanisms 20080101

• [Anticitrulline antibodies and wrist joint MRI parameters in patients with early arthritis].

  Terapevticheskii arkhiv 20080101

• Biomphalaria glabrata transcriptome: cDNA microarray profiling identifies resistant- and susceptible-specific gene expression in haemocytes from snail strains exposed to Schistosoma mansoni.

  BMC genomics 20080101

• Phosphodiesterase type-5 inhibitor and oxidative stress.

  International journal of immunopathology and pharmacology 20080101

• Living donor liver transplantation for type II citrullinemia from a heterozygous donor.

  Hepato-gastroenterology 20080101

• Nitric oxide and cyclic nucleotides: their roles in junction dynamics and spermatogenesis.

  Oxidative medicine and cellular longevity 20080101

• An insight into the biochemistry of inborn errors of metabolism for a clinical neurologist.

  Annals of Indian Academy of Neurology 20080101

• Simultaneous determination of L-arginine and 12 molecules participating in its metabolic cycle by gradient RP-HPLC method: application to human urine samples.

  Analytica chimica acta 20071219

• Poor diagnostic accuracy of a single fasting plasma citrulline concentration to assess intestinal energy absorption capacity.

  The American journal of gastroenterology 20071201

• L-arginine is essential for conidiation in the filamentous fungus Coniothyrium minitans.

  Fungal genetics and biology : FG & B 20071201

• Interaction between murine spf-ash mutation and genetic background yields different metabolic phenotypes.

  American journal of physiology. Endocrinology and metabolism 20071201

• Creatine synthesis: production of guanidinoacetate by the rat and human kidney in vivo.

  American journal of physiology. Renal physiology 20071201

• Maternal supplementation with citrulline increases renal nitric oxide in young spontaneously hypertensive rats and has long-term antihypertensive effects.

  Hypertension (Dallas, Tex. : 1979) 20071201

• Six cases of citrin deficiency in Korea.

  International journal of molecular medicine 20071201

• B cells in rheumatoid arthritis.

  Autoimmunity reviews 20071201

• Fine specificity of the anti-citrullinated protein antibody response is influenced by the shared epitope alleles.

  Arthritis and rheumatism 20071201

• Neonatal intrahepatic cholestasis caused by citrin deficiency in Korean infants.

  Journal of Korean medical science 20071201

• Endothelial dysfunction in diabetes mellitus.

  Vascular health and risk management 20071201

• Short-term effect of the HMG-CoA reductase inhibitor rosuvastatin on erythrocyte nitric oxide synthase activity.

  Vascular health and risk management 20071201

• Role of nitric oxide in inflammatory diseases.

  Inflammopharmacology 20071201

• Mitochondrial citrulline synthesis from ammonia and glutamine in the liver of ureogenic air-breathing catfish, Clarias batrachus (Linnaeus).

  Indian journal of experimental biology 20071201

• Blood citrulline level is an exclusionary marker for significant acute rejection after intestinal transplantation.

  Transplantation 20071115

• Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction.

  Circulation 20071113

• No evidence for modulation of endothelial nitric oxide synthase by the olive oil polyphenol hydroxytyrosol in human endothelial cells.

  Atherosclerosis 20071101

• Autoantibodies binding to citrullinated telopeptide of type II collagen and to cyclic citrullinated peptides predict synergistically the development of seropositive rheumatoid arthritis.

  Annals of the rheumatic diseases 20071101

• Brain stem NO modulates ventilatory acclimatization to hypoxia in mice.

  Journal of applied physiology (Bethesda, Md. : 1985) 20071101

• Manipulation of citrulline availability in humans.

  American journal of physiology. Gastrointestinal and liver physiology 20071101

• A clinical approach to autoantibody testing in systemic autoimmune rheumatic disorders.

  Autoimmunity reviews 20071101

• Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation.

  Arthritis and rheumatism 20071101

• Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.

  Journal of neurosurgery 20071101

• Intermediate outcomes after serial transverse enteroplasty in children with short bowel syndrome.

  Journal of pediatric surgery 20071101

• Oxygenase domain of Drosophila melanogaster nitric oxide synthase: unique kinetic parameters enable a more efficient NO release.

  Biochemistry 20071023

• Design and synthesis of C5 methylated L-arginine analogues as active site probes for nitric oxide synthase.

  Journal of the American Chemical Society 20071017

• ABAP: antibody-based assay for peptidylarginine deiminase activity.

  Analytical biochemistry 20071015

• GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): evaluation of the importance of S-nitrosothiols as inhibitors of DDAH activity in vitro and in vivo in humans.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015

• Nutrient intake in lysinuric protein intolerance.

  Journal of inherited metabolic disease 20071001

• Determination of dimethylarginine dimethylaminohydrolase activity in the kidney.

  Kidney international 20071001

• Liver manipulation causes hepatocyte injury and precedes systemic inflammation in patients undergoing liver resection.

  World journal of surgery 20071001

• Protein carbamylation links inflammation, smoking, uremia and atherogenesis.

  Nature medicine 20071001

• Nitric oxide metabolite levels in preterm labor.

  The journal of obstetrics and gynaecology research 20071001

• 'Multipurpose oxidase' in atherogenesis.

  Nature medicine 20071001

• NO synthase-dependent increases in extracellular citrulline levels in the nucleus accumbens in an emotional conditioned reflex.

  Neuroscience and behavioral physiology 20071001

• Concentration and composition of free amino acids and osmolalities of porcine oviductal and uterine fluid and their effects on development of porcine IVF embryos.

  Molecular reproduction and development 20070901

• D-glucose stimulation of L-arginine transport and nitric oxide synthesis results from activation of mitogen-activated protein kinases p42/44 and Smad2 requiring functional type II TGF-beta receptors in human umbilical vein endothelium.

  Journal of cellular physiology 20070901

• Apoptotic cells induce arginase II in macrophages, thereby attenuating NO production.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070901

• Dealcoholized red and white wines decrease oxidative stress associated with inflammation in rats.

  The British journal of nutrition 20070901

• Age decreases nitric oxide synthesis and responsiveness in human platelets and increases formation of monocyte-platelet aggregates.

  Cardiovascular research 20070901

• A multitracer stable isotope quantification of the effects of arginine intake on whole body arginine metabolism in neonatal piglets.

  American journal of physiology. Endocrinology and metabolism 20070901

• Prevalence and clinical significance of antibodies to citrullinated fibrinogen (ACF) in Chinese patients with rheumatoid arthritis.

  Clinical rheumatology 20070901

• Citrulline and the gut.

  Current opinion in clinical nutrition and metabolic care 20070901

• Specific amino acids in the critically ill patient--exogenous glutamine/arginine: a common denominator?

  Critical care medicine 20070901

• Tumor necrosis factor-alpha reduces argininosuccinate synthase expression and nitric oxide production in aortic endothelial cells.

  American journal of physiology. Heart and circulatory physiology 20070801

• Asymmetric dimethylarginine (ADMA) in vascular, renal and hepatic disease and the regulatory role of L-arginine on its metabolism.

  Molecular genetics and metabolism 20070801

• Analytical and diagnostic characteristics of 11 2nd- and 3rd-generation immunoenzymatic methods for the detection of antibodies to citrullinated proteins.

  Clinical chemistry 20070801

• Clinical evaluation of anti-mutated citrullinated vimentin by ELISA in rheumatoid arthritis.

  The Journal of rheumatology 20070801

• Interference with the citrulline-based nitric oxide synthase assay by argininosuccinate lyase activity in Arabidopsis extracts.

  The FEBS journal 20070801

• Pharmacokinetics and safety of intravenously administered citrulline in children undergoing congenital heart surgery: potential therapy for postoperative pulmonary hypertension.

  The Journal of thoracic and cardiovascular surgery 20070801

• Mutation and citrullination modifies vimentin to a novel autoantigen for rheumatoid arthritis.

  Arthritis and rheumatism 20070801

• The influence of improved glycaemic control with chlorpropamide on microvascular reactivity and nitric oxide synthase activity in diabetic rats.

  The Journal of pharmacy and pharmacology 20070801

• Antibodies to citrullinated human fibrinogen synthetic peptides in diagnosing rheumatoid arthritis.

  Journal of medicinal chemistry 20070726

• Peptidylarginine deiminase (PAD) 6 is essential for oocyte cytoskeletal sheet formation and female fertility.

  Molecular and cellular endocrinology 20070715

• L-arginine supplementation in peripheral arterial disease: no benefit and possible harm.

  Circulation 20070710

• The CO and CN(-) ligands to the active site Fe in [NiFe]-hydrogenase of Escherichia coli have different metabolic origins.

  FEBS letters 20070710

• Carbamoylphosphate serves as the source of CN(-), but not of the intrinsic CO in the active site of the regulatory [NiFe]-hydrogenase from Ralstonia eutropha.

  FEBS letters 20070710

• Cardiac nitric oxide synthases are elevated in dietary copper deficiency.

  The Journal of nutritional biochemistry 20070701

• Estrogen-enhanced peptidylarginine deiminase type IV gene (PADI4) expression in MCF-7 cells is mediated by estrogen receptor-alpha-promoted transfactors activator protein-1, nuclear factor-Y, and Sp1.

  Molecular endocrinology (Baltimore, Md.) 20070701

• Plasma citrulline concentration: a reliable marker of small bowel absorptive capacity independent of intestinal inflammation.

  The American journal of gastroenterology 20070701

• Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated.

  Journal of neuroscience research 20070701

• Post-translational modifications in the rat lumbar spinal cord in experimental autoimmune encephalomyelitis.

  Journal of proteome research 20070701

• Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients.

  Archives of neurology 20070701

• Does nitric oxide act in the ventromedial preoptic area to mediate oestrogen negative feedback in the seasonally anoestrous ewe?

  Reproduction (Cambridge, England) 20070701

• [Serum citrulline: a potential marker for intestinal epithelial mass and absorption capacity in short bowel syndrome patients].

  Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20070701

• [Citrullination, a novel post-translational modification of histone].

  Seikagaku. The Journal of Japanese Biochemical Society 20070701

• [Rheumatology 2007].

  Deutsche medizinische Wochenschrift (1946) 20070622

• Probing heme coordination states of inducible nitric oxide synthase with a ReI(imidazole-alkyl-nitroarginine) sensitizer-wire.

  The journal of physical chemistry. B 20070621

• Biomarkers for radiation-induced small bowel epithelial damage: an emerging role for plasma Citrulline.

  World journal of gastroenterology 20070614

• Protein arginine deiminase 4: evidence for a reverse protonation mechanism.

  Biochemistry 20070605

• Proteomic analysis of secreted proteins in early rheumatoid arthritis: anti-citrulline autoreactivity is associated with up regulation of proinflammatory cytokines.

  Annals of the rheumatic diseases 20070601

• Intestinal and hepatic metabolism of glutamine and citrulline in humans.

  The Journal of physiology 20070601

• L-citrulline inhibits [3H]acetylcholine release from rat motor nerve terminals by increasing adenosine outflow and activation of A1 receptors.

  British journal of pharmacology 20070601

• Low citrulline may not be diagnostic of ornithine transcarbamylase deficiency: a case report.

  Journal of inherited metabolic disease 20070601

• A trial with N-carbamylglutamate may not detect all patients with NAGS deficiency and neonatal onset.

  Journal of inherited metabolic disease 20070601

• Nephropathy advancing to end-stage renal disease: a novel complication of lysinuric protein intolerance.

  The Journal of pediatrics 20070601

• [Glutamatergic regulation of citrulline extracellular level in the nucleus accumbens during acquisition and expression of conditioned emotional response].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20070601

• Citrullination by peptidylarginine deiminase in rheumatoid arthritis.

  Annals of the New York Academy of Sciences 20070601

• Urea production and arginine metabolism are reduced in the growth restricted ovine foetus.

  Animal : an international journal of animal bioscience 20070601

• Substrate- and isoform-specific dioxygen complexes of nitric oxide synthase.

  Journal of the American Chemical Society 20070530

• Methods using stable isotopes to measure nitric oxide (NO) synthesis in the L-arginine/NO pathway in health and disease.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070515

• Arginine, citrulline and nitrate concentrations in the cerebrospinal fluid from patients with acute hydrocephalus.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070515

• High-throughput liquid chromatographic-tandem mass spectrometric determination of arginine and dimethylated arginine derivatives in human and mouse plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070515

• A stable-isotope based technique for the determination of dimethylarginine dimethylaminohydrolase (DDAH) activity in mouse tissue.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070515

• Accurate quantification of dimethylamine (DMA) in human plasma and serum by GC-MS and GC-tandem MS as pentafluorobenzamide derivative in the positive-ion chemical ionization mode.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070515

• Activation of peroxynitrite by inducible nitric-oxide synthase: a direct source of nitrative stress.

  The Journal of biological chemistry 20070511

• Paracetamol inhibits nitric oxide synthesis in murine spinal cord slices.

  European journal of pharmacology 20070507

• Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease.

  American journal of physiology. Gastrointestinal and liver physiology 20070501

• Ubiquitous presence of argininosuccinate at millimolar levels in the central nervous system of Aplysia californica.

  Journal of neurochemistry 20070501

• Role and significance of plasma citrulline in the early phase after small bowel transplantation in pigs.

  Transplant international : official journal of the European Society for Organ Transplantation 20070501

• Effect of ocular hypertension on retinal nitridergic pathway activity.

  Investigative ophthalmology & visual science 20070501

• Mutation of superoxide dismutase elevates reactive species: comparison of nitration and oxidation of proteins in different brain regions of transgenic mice with amyotrophic lateral sclerosis.

  Neuroscience 20070425

• Association between glutamine extraction and release of citrulline and glycine by the human small intestine.

  Life sciences 20070424

• Methylation of arginine residues interferes with citrullination by peptidylarginine deiminases in vitro.

  Journal of molecular biology 20070406

• Synthesis of proteins containing modified arginine residues.

  Biochemistry 20070403

• Anti-cyclic citrullinated peptide positivity in non-rheumatoid arthritis disease samples: citrulline-dependent or not?

  Annals of the rheumatic diseases 20070401

• Long-term stability of amino acids and acylcarnitines in dried blood spots.

  Clinical chemistry 20070401

• Vestibular neurons in the rat contain imidazoleacetic acid-ribotide, a putative neurotransmitter involved in blood pressure regulation.

  The Journal of comparative neurology 20070401

• Clinical pictures of 75 patients with neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD).

  Journal of inherited metabolic disease 20070401

• Divergent polyamine metabolism in the Apicomplexa.

  Microbiology (Reading, England) 20070401

• The endogenous neurotransmitter, serotonin, modifies neuronal nitric oxide synthase activities.

  Free radical research 20070401

• [The effect of arginine and its metabolites on tissue culture of rat myocardium].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20070401

• Modulation of parathion toxicity by glucose feeding: Is nitric oxide involved?

  Toxicology and applied pharmacology 20070301

• Neuronal oxidative injury and dendritic damage induced by carbofuran: protection by memantine.

  Toxicology and applied pharmacology 20070301

• Dysregulation of C/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease.

  Human molecular genetics 20070301

• The functional haplotype of peptidylarginine deiminase IV (S55G, A82V and A112G) associated with susceptibility to rheumatoid arthritis dominates apoptosis of acute T leukemia Jurkat cells.

  Apoptosis : an international journal on programmed cell death 20070301

• The effect of n-3 PUFA on eNOS activity and expression in Ea hy 926 cells.

  Prostaglandins, leukotrienes, and essential fatty acids 20070301

• Technical and diagnostic performance of 6 assays for the measurement of citrullinated protein/peptide antibodies in the diagnosis of rheumatoid arthritis.

  Clinical chemistry 20070301

• Extracellular citrulline levels in the nucleus accumbens during the acquisition and extinction of a classical conditioned reflex with pain reinforcement.

  Neuroscience and behavioral physiology 20070301

• Citrin deficiency: a novel cause of failure to thrive that responds to a high-protein, low-carbohydrate diet.

  Pediatrics 20070301

• Watermelon consumption increases plasma arginine concentrations in adults.

  Nutrition (Burbank, Los Angeles County, Calif.) 20070301

• Renal tissue NO and intrarenal haemodynamics during experimental variations of NO content in anaesthetised rats.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070301

• Coordination of kidney filtration and tubular reabsorption: considerations on the regulation of metabolic demand for tubular reabsorption.

  Acta physiologica Hungarica 20070301

• Direct detection of reactive nitrogen species in experimental autoimmune uveitis.

  Korean journal of ophthalmology : KJO 20070301

• Nucleotide receptor signalling and the generation of reactive oxygen species.

  Purinergic signalling 20070301

• Citrullinated collagens in the pathogenesis of rheumatoid arthritis.

  Expert review of clinical immunology 20070301

• Conditional neuronal nitric oxide synthase overexpression impairs myocardial contractility.

  Circulation research 20070216

• Insight into the catalytic mechanism of arginine deiminase: functional studies on the crucial sites.

  Proteins 20070215

• Renal cell carcinoma does not express argininosuccinate synthetase and is highly sensitive to arginine deprivation via arginine deiminase.

  International journal of cancer 20070215

• Effect of agmatine on brain L-citrulline production during morphine withdrawal in rats: a microdialysis study in nucleus accumbens.

  Brain research 20070209

• Radiochemical HPLC detection of arginine metabolism: measurement of nitric oxide synthesis and arginase activity in vascular tissue.

  Nitric oxide : biology and chemistry 20070201

• A tale of two citrullines--structural and functional aspects of myelin basic protein deimination in health and disease.

  Neurochemical research 20070201

• Free amino acid and dipeptide changes in the body fluids from Alzheimer's disease subjects.

  Amino acids 20070201

• The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis.

  Neurochemical research 20070201

• Allosteric inhibition of rat neuronal nitric-oxide synthase caused by interference with the binding of calmodulin to the enzyme.

  Biochimica et biophysica acta 20070201

• An OTC deficiency 'phenocopy' in association with Klinefelter syndrome.

  Journal of inherited metabolic disease 20070201

• Long-term oral lysine supplementation in lysinuric protein intolerance.

  Metabolism: clinical and experimental 20070201

• Arginine deficiency in preconfluent intestinal Caco-2 cells modulates expression of proteins involved in proliferation, apoptosis, and heat shock response.

  Proteomics 20070201

• Inhibition of adenine nucleotide transport in rat liver mitochondria by long-chain acyl-coenzyme A beta-oxidation intermediates.

  Biochemical and biophysical research communications 20070126

• Effects of a pomegranate fruit extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis.

  Cardiovascular research 20070115

• Influence of pegylated interferon-alpha therapy on plasma levels of citrulline and arginine in melanoma patients.

  Amino acids 20070101

• Up regulation of monocyte chemoattractant protein-1 expression in anti-citrulline antibody and immunoglobulin M rheumatoid factor positive subjects precedes onset of inflammatory response and development of overt rheumatoid arthritis.

  Annals of the rheumatic diseases 20070101

• Citrullination in extra-articular manifestations of rheumatoid arthritis.

  Rheumatology (Oxford, England) 20070101

• Molecular basis for the antiproliferative effect of agmatine in tumor cells of colonic, hepatic, and neuronal origin.

  Molecular pharmacology 20070101

• Smoking as a trigger for inflammatory rheumatic diseases.

  Current opinion in rheumatology 20070101

• Acute alterations of glutamate, glutamine, GABA, and other amino acids after spinal cord contusion in rats.

  Neurochemical research 20070101

• Does the ornithine-alpha-ketoglutarate ratio influence ornithine alpha-ketoglutarate metabolism in healthy rats?

  Metabolism: clinical and experimental 20070101

• CD151 gene delivery increases eNOS activity and induces ECV304 migration, proliferation and tube formation.

  Acta pharmacologica Sinica 20070101

• Are plasma citrulline and glutamine biomarkers of intestinal absorptive function in patients with short bowel syndrome?

  JPEN. Journal of parenteral and enteral nutrition 20070101

• Pegylated recombinant human arginase (rhArg-peg5,000mw) inhibits the in vitro and in vivo proliferation of human hepatocellular carcinoma through arginine depletion.

  Cancer research 20070101

• [Adult-onset citrullinemia].

  No to shinkei = Brain and nerve 20070101

• Intermediate metabolism in association with the amino acid profile during the third trimester of normal pregnancy and diet-controlled gestational diabetes.

  American journal of obstetrics and gynecology 20070101

• MELAS and L-arginine therapy.

  Mitochondrion 20070101

• Recurrent headache as the main symptom of acquired cerebral toxoplasmosis in nonhuman immunodeficiency virus-infected subjects with no lymphadenopathy: the parasite may be responsible for the neurogenic inflammation postulated as a cause of different types of headaches.

  American journal of therapeutics 20070101

• Pharmacologic levels of dietary arginine in CB6F1 mice increase serum ammonia in the healthy state and serum nitrite in endotoxemia.

  JPEN. Journal of parenteral and enteral nutrition 20070101

• Does periadventitial fat-derived nitric oxide play a role in improved saphenous vein graft patency in patients undergoing coronary artery bypass surgery?

  Journal of vascular research 20070101

• A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for autoantibody production in rheumatoid arthritis.

  Arthritis research & therapy 20070101

• [Adult-onset citrullinemia].

  Brain and nerve = Shinkei kenkyu no shinpo 20070101

• Genome sequencing shows that European isolates of Francisella tularensis subspecies tularensis are almost identical to US laboratory strain Schu S4.

  PloS one 20070101

• METANNOGEN: compiling features of biochemical reactions needed for the reconstruction of metabolic networks.

  BMC systems biology 20070101

• Diagnostic value of anti-cyclic citrullinated peptide antibodies in Greek patients with rheumatoid arthritis.

  BMC musculoskeletal disorders 20070101

• Effects of nebulized ketamine on allergen-induced airway hyperresponsiveness and inflammation in actively sensitized Brown-Norway rats.

  Journal of inflammation (London, England) 20070101

• Auxin and nitric oxide control indeterminate nodule formation.

  BMC plant biology 20070101

• Arthritis suppression by NADPH activation operates through an interferon-beta pathway.

  BMC biology 20070101

• Resting tension affects eNOS activity in a calcium-dependent way in airways.

  Mediators of inflammation 20070101

• Anti-citrulline antibodies in the diagnosis and prognosis of rheumatoid arthritis: evolving concepts.

  Critical reviews in clinical laboratory sciences 20070101

• Nitric oxide inhibition rapidly increases blood pressure with no change in outcome in cardiogenic shock: the TRIUMPH trial.

  Critical care (London, England) 20070101

• Ovarian gene expression in the absence of FIGLA, an oocyte-specific transcription factor.

  BMC developmental biology 20070101

• Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions.

  BMC genomics 20070101

• Enhancement of intracellular gamma-tocopherol levels in cytokine-stimulated C3H 10T1/2 fibroblasts: relation to NO synthesis, isoprostane formation, and tocopherol oxidation.

  BMC chemical biology 20070101

• Critical sample pretreatment in monitoring dried blood spot citrulline.

  Clinica chimica acta; international journal of clinical chemistry 20070101

• The route of administration (enteral or parenteral) affects the conversion of isotopically labeled L-[2-15N]glutamine into citrulline and arginine in humans.

  JPEN. Journal of parenteral and enteral nutrition 20070101

• Integrated network reconstruction, visualization and analysis using YANAsquare.

  BMC bioinformatics 20070101

• Hydrogen peroxide promotes endothelial dysfunction by stimulating multiple sources of superoxide anion radical production and decreasing nitric oxide bioavailability.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

• Living with an imperfect cell wall: compensation of femAB inactivation in Staphylococcus aureus.

  BMC genomics 20070101

• Enhanced astrocytic nitric oxide production and neuronal modifications in the neocortex of a NOS2 mutant mouse.

  PloS one 20070101

• Role of eNOS phosphorylation at Ser-116 in regulation of eNOS activity in endothelial cells.

  Vascular pharmacology 20070101

• Species status of Neisseria gonorrhoeae: evolutionary and epidemiological inferences from multilocus sequence typing.

  BMC biology 20070101

• Cells of the synovium in rheumatoid arthritis. Dendritic cells.

  Arthritis research & therapy 20070101

• Endothelial nitric oxide production is tightly coupled to the citrulline-NO cycle.

  Nitric oxide : biology and chemistry 20070101

• Differential responsiveness to immunoablative therapy in refractory rheumatoid arthritis is associated with level and avidity of anti-cyclic citrullinated protein autoantibodies: a case study.

  Arthritis research & therapy 20070101

• Effect of arginine and its metabolites on the rat myocardium in an organotypic tissue culture.

  Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20070101

• Pattern of macrophage activation in yersinia-resistant and yersinia-susceptible strains of mice.

  Microbiology and immunology 20070101

• [Effect of the arginine and its metabolites on the rat myocardium in organothypic tissue culture in young and old rats].

  Advances in gerontology = Uspekhi gerontologii 20070101

• Therapeutic T cells induce tumor-directed chemotaxis of innate immune cells through tumor-specific secretion of chemokines and stimulation of B16BL6 melanoma to secrete chemokines.

  Journal of translational medicine 20070101

• Oral administration of chicken breast extract increases brain carnosine and anserine concentrations in rats.

  Nutritional neuroscience 20070101

• Alterations in nitric oxide synthase isoforms in acute lower limb ischemia and reperfusion.

  Angiology 20070101

• Bioinformatic evaluation of L-arginine catabolic pathways in 24 cyanobacteria and transcriptional analysis of genes encoding enzymes of L-arginine catabolism in the cyanobacterium Synechocystis sp. PCC 6803.

  BMC genomics 20070101

• Impact of light on Hypocrea jecorina and the multiple cellular roles of ENVOY in this process.

  BMC genomics 20070101

• Cerebrospinal fluid amino acids in pathological gamblers and healthy controls.

  Neuropsychobiology 20070101

• iNOS activity in the aged rat liver tissue.

  Journal of biological regulators and homeostatic agents 20070101

• A genome-wide ordered-subset linkage analysis for rheumatoid arthritis.

  BMC proceedings 20070101

• Rheumatoid arthritis, item response theory, Blom transformation, and mixed models.

  BMC proceedings 20070101

• Identification and quantitation of asparagine and citrulline using high-performance liquid chromatography (HPLC).

  Analytical chemistry insights 20070101

• Methodology and applications of disease biomarker identification in human serum.

  Biomarker insights 20070101

• The Clinical Application of Anti-CCP in Rheumatoid Arthritis and Other Rheumatic Diseases.

  Biomarker insights 20070101

• Identifying Stress Transcription Factors Using Gene Expression and TF-Gene Association Data.

  Bioinformatics and biology insights 20070101

• The relationship of arginine deprivation, argininosuccinate synthetase and cell death in melanoma.

  Drug target insights 20070101

• nNOS is involved in behavioral thermoregulation of newborn rats during hypoxia.

  Physiology & behavior 20061230

• Role of Toll-like receptor 4 for the pathogenesis of acute lung injury in Gram-negative sepsis.

  European journal of anaesthesiology 20061201

• Insulin restores glucose inhibition of adenosine transport by increasing the expression and activity of the equilibrative nucleoside transporter 2 in human umbilical vein endothelium.

  Journal of cellular physiology 20061201

• Genes, environment and immunity in the development of rheumatoid arthritis.

  Current opinion in immunology 20061201

• Determination of homocitrulline in urine of patients with HHH syndrome by liquid chromatography tandem mass spectrometry.

  Analytical and bioanalytical chemistry 20061201

• Degradation of arginine by Slackia exigua ATCC 700122 and Cryptobacterium curtum ATCC 700683.

  Oral microbiology and immunology 20061201

• Von Willebrand factor activates endothelial nitric oxide synthase in blood platelets by a glycoprotein Ib-dependent mechanism.

  Journal of thrombosis and haemostasis : JTH 20061201

• Arginase activity is increased by thrombin: a mechanism for endothelial dysfunction in arterial thrombosis.

  Journal of the American College of Surgeons 20061201

• Janus-faced role of endothelial NO synthase in vascular disease: uncoupling of oxygen reduction from NO synthesis and its pharmacological reversal.

  Biological chemistry 20061201

• Nitric oxide precursors and congenital cardiac surgery: a randomized controlled trial of oral citrulline. Definition of pulmonary hypertension in Fontan circulation?

  The Journal of thoracic and cardiovascular surgery 20061201

• Elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine in citrullinemia.

  Metabolism: clinical and experimental 20061201

• Can we rely on anti-citrulline antibody determination for the diagnosis of early rheumatoid arthritis?

  The Journal of rheumatology 20061201

• [Effect of puerarin on ADMA-DDAH system in human umbilical vein endothelial cells cultured with oxidized free radical].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20061201

• Isosorbide dinitrate-hydralazine combination therapy in African Americans with heart failure.

  Vascular health and risk management 20061201

• Arginine and urea metabolism in the liver graft: A study using microdialysis in human orthotopic liver transplantation.

  Transplantation 20061127

• Characterization of proline, citrulline, and uracil auxotrophic plasmid-carrying Neisseria gonorrhoeae strains in Canada, 1993-2003.

  Sexually transmitted diseases 20061101

• Serum autoantibodies that bind citrullinated fibrinogen are frequently found in patients with rheumatoid arthritis.

  The Journal of rheumatology 20061101

• Genetic manipulation of a primary metabolic pathway for L-ornithine production in Escherichia coli.

  Biotechnology letters 20061101

• Glutamate:glyoxylate aminotransferase modulates amino acid content during photorespiration.

  Plant physiology 20061101

• The value of plasma citrulline to predict mucosal injury in intestinal allografts.

  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20061101

• Peptidylarginine deiminases and deimination in biology and pathology: relevance to skin homeostasis.

  Journal of dermatological science 20061101

• Effects of local infusions of apomorphine on the extracellular citrulline level in the striatum: Involvement of D1 and D2 dopamine receptors.

  Neuroscience and behavioral physiology 20061101

• Ammonium toxicity and potassium limitation in yeast.

  PLoS biology 20061101

• Individual differences and repeatability of post-prandial changes of plasma-free amino acids in young horses.

  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20061101

• Citrullinated proteins in rheumatoid arthritis: crucial...but not sufficient!

  Arthritis and rheumatism 20061101

• Activation of nitric oxide signaling by the rheumatoid arthritis shared epitope.

  Arthritis and rheumatism 20061101

• Reduced intestinal and renal amino acid transport in PDK1 hypomorphic mice.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20061101

• Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20061101

• Citrullinated antigens: just diagnostic tools or pathogenic targets in rheumatoid arthritis?

  The Journal of rheumatology 20061101

• Autoantibodies to citrullinated antigens in (early) rheumatoid arthritis.

  Autoimmunity reviews 20061101

• European Academy of Paediatrics, Barcelona, Spain, October 7-10, 2006. Abstracts.

  European journal of pediatrics 20061101

• mRNA and protein expression and activities of nitric oxide synthases in the lumbar spinal cord of neonatal rats after sciatic nerve transection and melatonin administration.

  Neuroscience letters 20061023

• Impaired formalin-evoked changes of spinal amino acid levels in diabetic rats.

  Brain research 20061018

• Effects of N-methyl-D-aspartate on extracellular citrulline level in the rat nucleus accumbens.

  Neuroscience letters 20061016

• Mechanisms underlying beta2-adrenoceptor-mediated nitric oxide generation by human umbilical vein endothelial cells.

  The Journal of physiology 20061015

• Understanding the enzymatic activity of 4-oxalocrotonate tautomerase and its mutant analogues: a computational study.

  The journal of physical chemistry. B 20061005

• Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization.

  Biochemistry 20061003

• Effect of postinjury intravenous or intrathecal methylprednisolone on spinal cord excitatory amino-acid release, nitric oxide generation, PGE2 synthesis, and myeloperoxidase content in a pig model of acute spinal cord injury.

  Spinal cord 20061001

• Route of administration (enteral or parenteral) affects the contribution of L-glutamine to de novo L-arginine synthesis in mice: a stable-isotope study.

  American journal of physiology. Endocrinology and metabolism 20061001

• Increased cardiac endothelial nitric oxide synthase expression in patients taking angiotensin-converting enzyme inhibitor therapy.

  European journal of clinical investigation 20061001

• Homozygous SLC25A13 mutation in a Taiwanese patient with adult-onset citrullinemia complicated with steatosis and hepatocellular carcinoma.

  Journal of the Formosan Medical Association = Taiwan yi zhi 20061001

• Amino acids mediate colony and cell differentiation in the fungal pathogen Candida parapsilosis.

  Microbiology (Reading, England) 20061001

• The enduracidin biosynthetic gene cluster from Streptomyces fungicidicus.

  Microbiology (Reading, England) 20061001

• The small untranslated RNA SR1 from the Bacillus subtilis genome is involved in the regulation of arginine catabolism.

  Molecular microbiology 20061001

• Autoimmunity to citrullinated type II collagen in rheumatoid arthritis.

  Modern rheumatology 20061001

• Synthesis of overlapping fibrin citrullinated peptides and their use for diagnosing rheumatoid arthritis.

  Chemical biology & drug design 20061001

• Role of the L-citrulline/L-arginine cycle in iNANC nerve-mediated nitric oxide production and airway smooth muscle relaxation in allergic asthma.

  European journal of pharmacology 20060928

• Experimental autoimmune encephalomyelitis induction in peptidylarginine deiminase 2 knockout mice.

  The Journal of comparative neurology 20060910

• [Significance of citrullinated collagen type II and its antibodies in rheumatoid arthritis].

  Zhonghua yi xue za zhi 20060905

• Cycling of NADPH by glucose 6-phosphate dehydrogenase optimizes the spectrophotometric assay of nitric oxide synthase activity in cell lysates.

  Nitric oxide : biology and chemistry 20060901

• Regulatory role for the arginine-nitric oxide pathway in metabolism of energy substrates.

  The Journal of nutritional biochemistry 20060901

• Citrullination is an inflammation-dependent process.

  Annals of the rheumatic diseases 20060901

• Citrulline modulates muscle protein metabolism in old malnourished rats.

  American journal of physiology. Endocrinology and metabolism 20060901

• Phe-met-arg-phe (FMRF)-amide is a substrate source of NO synthase in the gastropod nervous system.

  Cell and tissue research 20060901

• Acute renal response to LPS: impaired arginine production and inducible nitric oxide synthase activity.

  American journal of physiology. Regulatory, integrative and comparative physiology 20060901

• PIN inhibits nitric oxide and superoxide production from purified neuronal nitric oxide synthase.

  Biochimica et biophysica acta 20060901

• Testosterone induction of male-typical sexual behavior is associated with increased preoptic NADPH diaphorase and citrulline production in female whiptail lizards.

  Journal of neurobiology 20060901

• In the rat, citrullinated autologous fibrinogen is immunogenic but the induced autoimmune response is not arthritogenic.

  Clinical and experimental immunology 20060901

• Regional differences in nitric oxide-mediated vasorelaxation in porcine pulmonary arteries.

  Acta anaesthesiologica Scandinavica 20060901

• Changes in amino acids and nitric oxide concentration in cerebrospinal fluid during labor pain.

  Neurochemical research 20060901

• Anti-cyclic citrullinated peptide antibody and rheumatoid factor isotypes in African Americans with early rheumatoid arthritis.

  Arthritis and rheumatism 20060901

• Effects of glutamic acid and taurine on total parenteral nutrition.

  Journal of pediatric surgery 20060901

• Intricate knots in proteins: Function and evolution.

  PLoS computational biology 20060901

• NG-hydroxyguanidines from primary amines.

  Organic letters 20060831

• Histone citrullination by protein arginine deiminase: is arginine methylation a green light or a roadblock?

  ACS chemical biology 20060822

• Hyperoxia increases hepatic arginase expression and ornithine production in mice.

  Toxicology and applied pharmacology 20060815

• Galactosyl derivatives of L-arginine and D-arginine: synthesis, stability, cell permeation, and nitric oxide production in pituitary GH3 cells.

  Journal of medicinal chemistry 20060810

• Changes in concentration of cerebrospinal fluid components in patients with traumatic brain injury.

  Brain research 20060809

• Blood cell NO synthesis in response to exercise.

  Nitric oxide : biology and chemistry 20060801

• Citrullinated fibrinogen detected as a soluble citrullinated autoantigen in rheumatoid arthritis synovial fluids.

  Annals of the rheumatic diseases 20060801

• Infected chronic wounds show different local and systemic arginine conversion compared with acute wounds.

  The Journal of surgical research 20060801

• NF-Y and Sp1/Sp3 are involved in the transcriptional regulation of the peptidylarginine deiminase type III gene (PADI3) in human keratinocytes.

  The Biochemical journal 20060801

• Time course of acylcarnitine elevation in neonatal intrahepatic cholestasis caused by citrin deficiency.

  Journal of inherited metabolic disease 20060801

• Adverse effects of cigarette smoke on NO bioavailability: role of arginine metabolism and oxidative stress.

  Hypertension (Dallas, Tex. : 1979) 20060801

• Neuronal nitric oxide synthase in the gill of the killifish, Fundulus heteroclitus.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060801

• PADI4 gene in multiple sclerosis: a family-based association study.

  Journal of neuroimmunology 20060801

• Epitopes of human fibrin recognized by the rheumatoid arthritis-specific autoantibodies to citrullinated proteins.

  European journal of immunology 20060801

• Cutting edge: unique T cells that recognize citrullinated peptides are a feature of protein immunization.

  Journal of immunology (Baltimore, Md. : 1950) 20060801

• Decreased nitric oxide production in the rat brain after chronic arsenic exposure.

  Neurochemical research 20060801

• Ammonium chloride and alpha-ketoglutaric acid increase glutamine availability in the early phase of induced acute metabolic acidosis.

  Acta anaesthesiologica Scandinavica 20060801

• Expression, purification and preliminary crystallographic analysis of oligopeptidase B from Trypanosoma brucei.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060801

• Impact of winemaking practices on arginine and citrulline metabolism during and after malolactic fermentation.

  Journal of applied microbiology 20060801

• Characterization of cationic amino acid transport systems in rat erythrocytes: lack of effect of uraemia on L-arginine influx.

  Clinical and experimental pharmacology & physiology 20060801

• [Immunologic laboratory testing in clinical practice for rheumatoid arthritis].

  Rinsho byori. The Japanese journal of clinical pathology 20060801

• [The presence of nitric oxide synthase in mucosal epithelial cells of the frog urinary bladder].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20060801

• Characterization of late-onset citrullinemia 1 in a Korean patient: confirmation by argininosuccinate synthetase gene mutation analysis.

  Journal of biochemistry and molecular biology 20060731

• Determination of free amino acids and related compounds in amniotic fluid by capillary electrophoresis with contactless conductivity detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060724

• Inhaled L-arginine improves exhaled nitric oxide and pulmonary function in patients with cystic fibrosis.

  American journal of respiratory and critical care medicine 20060715

• Synthetic vascular prosthesis impregnated with mesenchymal stem cells overexpressing endothelial nitric oxide synthase.

  Circulation 20060704

• Pharmacological strategies for the regulation of inducible nitric oxide synthase: neurodegenerative versus neuroprotective mechanisms.

  Neurochemistry international 20060701

• Pegylated arginine deiminase: a novel anticancer enzyme agent.

  Expert opinion on investigational drugs 20060701

• Nitric oxide precursors and congenital heart surgery: a randomized controlled trial of oral citrulline.

  The Journal of thoracic and cardiovascular surgery 20060701

• L-arginine: a new opportunity in the management of clinical derangements in dialysis patients.

  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20060701

• Inducible nitric oxide synthase catalyzes ethanol oxidation to alpha-hydroxyethyl radical and acetaldehyde.

  Toxicology 20060615

• Increased nitric oxide (NO) pathway metabolites in the vitreous fluid of patients with rhegmatogenous retinal detachment or diabetic traction retinal detachment.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20060601

• Regulation of inducible nitric oxide synthase in post-operative adhesions.

  Human reproduction (Oxford, England) 20060601

• Inhibition of protein synthesis by activation of NMDA receptors in cultured retinal cells: a new mechanism for the regulation of nitric oxide production.

  Journal of neurochemistry 20060601

• Local arginine supplementation results in sustained wound nitric oxide production and reductions in vascular endothelial growth factor expression and granulation tissue formation.

  The Journal of surgical research 20060601

• Suppression of human immunodeficiency virus type 1 replication by arginine deiminase of Mycoplasma arginini.

  The Journal of general virology 20060601

• Proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis.

  Investigative ophthalmology & visual science 20060601

• HLA and RA revisited: citrullinated food for the SE hypothesis, the DR6 effect, and NIMA.

  Human immunology 20060601

• Serum citrulline levels in infants with short bowel syndrome.

  The Journal of pediatrics 20060601

• Potent cytotoxicity of an auristatin-containing antibody-drug conjugate targeting melanoma cells expressing melanotransferrin/p97.

  Molecular cancer therapeutics 20060601

• [NO-synthase dependent increase in citrulline extracellular level in the nucleus accumbens during acquisition and expression of conditioned emotional response].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20060601

• Substrate-assisted cysteine deprotonation in the mechanism of dimethylargininase (DDAH) from Pseudomonas aeruginosa.

  Biochemistry 20060502

• Granulocyte-macrophage colony-stimulating factor increases L-arginine transport through the induction of CAT2 in bone marrow-derived macrophages.

  American journal of physiology. Cell physiology 20060501

• Studies on nitric oxide synthase activity in haemocytes of shrimps Fenneropenaeus chinensis and Marsupenaeus japonicus after white spot syndrome virus infection.

  Nitric oxide : biology and chemistry 20060501

• Specific modification of peptide-bound citrulline residues.

  Analytical biochemistry 20060501

• Short bowel syndrome and intestinal transplantation in children.

  Current opinion in clinical nutrition and metabolic care 20060501

• Structure of the mammalian NOS regulator dimethylarginine dimethylaminohydrolase: A basis for the design of specific inhibitors.

  Structure (London, England : 1993) 20060501

• Statins blunt thrombin-induced down-regulation of endothelial nitric oxide synthase expression in human endothelial cells.

  Journal of cardiovascular pharmacology 20060501

• Activity of L-alpha-amino acids at the promiscuous goldfish odorant receptor 5.24.

  European journal of pharmacology 20060424

• Lysosomal trafficking and cysteine protease metabolism confer target-specific cytotoxicity by peptide-linked anti-CD30-auristatin conjugates.

  The Journal of biological chemistry 20060414

• Endothelial nitric oxide synthase in vascular disease: from marvel to menace.

  Circulation 20060404

• The regulatory PII protein controls arginine biosynthesis in Arabidopsis.

  FEBS letters 20060403

• Pathomechanisms in rheumatoid arthritis--time for a string theory?

  The Journal of clinical investigation 20060403

• The functional integrity of a normothermic perfusion system using artificial blood in pig liver.

  The Journal of surgical research 20060401

• [Histone demethylation isn't what it used to be].

  Medecine sciences : M/S 20060401

• [A difficult and complicated case study: neonatal intrahepatic cholestasis caused by citrin deficiency].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20060401

• [Antibodies to citrullinated proteins in rheumatoid arthritis].

  Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20060401

• L-citrulline reduces time to exhaustion and insulin response to a graded exercise test.

  Medicine and science in sports and exercise 20060401

• Arginine, arginine analogs and nitric oxide production in chronic kidney disease.

  Nature clinical practice. Nephrology 20060401

• Agmatine stimulates hepatic fatty acid oxidation: a possible mechanism for up-regulation of ureagenesis.

  The Journal of biological chemistry 20060331

• Role of endothelial nitric oxide synthase in the regulation of SREBP activation by oxidized phospholipids.

  Circulation research 20060331

• Differential effects of alkyl- and arylguanidines on the stability and reactivity of inducible NOS heme-dioxygen complexes.

  Biochemistry 20060328

• Identification of citrullinated eukaryotic translation initiation factor 4G1 as novel autoantigen in rheumatoid arthritis.

  Biochemical and biophysical research communications 20060303

• Expression of peptidylarginine deiminase type 4 (PAD4) in various tumors.

  Molecular carcinogenesis 20060301

• Nitric oxide synthase localization in the rat neutrophils: immunocytochemical, molecular, and biochemical studies.

  Journal of leukocyte biology 20060301

• A stress surveillance system based on calcium and nitric oxide in marine diatoms.

  PLoS biology 20060301

• Deiminated Epstein-Barr virus nuclear antigen 1 is a target of anti-citrullinated protein antibodies in rheumatoid arthritis.

  Arthritis and rheumatism 20060301

• Citrulline and ammonia accumulating in citrullinemia reduces antioxidant capacity of rat brain in vitro.

  Metabolic brain disease 20060301

• Is occupational exposure to mineral oil a risk factor for rheumatoid arthritis?

  Nature clinical practice. Rheumatology 20060301

• Vascular and renal effects of dopamine during extracellular volume expansion: Role of nitric oxide pathway.

  Life sciences 20060227

• [Diagnostic and prognostic significance of antibodies against citrullinated peptides].

  Deutsche medizinische Wochenschrift (1946) 20060210

• Plasma arginine correlations in trauma and sepsis.

  Amino acids 20060201

• Functional characterization of brain mitochondrial nitric oxide synthase during hypertension and aging.

  Amino acids 20060201

• Plasma free amino acids and their metabolites in Taiwanese patients on hemodialysis and continuous ambulatory peritoneal dialysis.

  Clinica chimica acta; international journal of clinical chemistry 20060201

• Application of electron spin resonance spin-trapping technique for evaluation of substrates and inhibitors of nitric oxide synthase.

  Analytical biochemistry 20060201

• Nickel deficiency disrupts metabolism of ureides, amino acids, and organic acids of young pecan foliage.

  Plant physiology 20060201

• Serial transverse enteroplasty enhances intestinal function in a model of short bowel syndrome.

  Annals of surgery 20060201

• A case of adult-onset type II citrullinemia--deterioration of clinical course after infusion of hyperosmotic and high sugar solutions.

  Medical science monitor : international medical journal of experimental and clinical research 20060201

• Guidelines for management of home parenteral support in adult chronic intestinal failure patients.

  Gastroenterology 20060201

• Comparative genomics of emerging human ehrlichiosis agents.

  PLoS genetics 20060201

• Overexpression of peptidylarginine deiminase IV features in apoptosis of haematopoietic cells.

  Apoptosis : an international journal on programmed cell death 20060201

• Ginsenoside R(e) increases fertile and asthenozoospermic infertile human sperm motility by induction of nitric oxide synthase.

  Archives of pharmacal research 20060201

• HHH syndrome (hyperornithinaemia, hyperammonaemia, homocitrullinuria), with fulminant hepatitis-like presentation.

  Journal of inherited metabolic disease 20060201

• [Whole blood citrulline levels in patients with coeliac disease].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20060201

• Kinetic analysis of Pseudomonas aeruginosa arginine deiminase mutants and alternate substrates provides insight into structural determinants of function.

  Biochemistry 20060131

• Effect of phosphorylation of myelin basic protein by MAPK on its interactions with actin and actin binding to a lipid membrane in vitro.

  Biochemistry 20060117

• Reduced L-arginine level and decreased placental eNOS activity in preeclampsia.

  Placenta 20060101

• Histone arginine methylation and its dynamic regulation.

  Frontiers in bioscience : a journal and virtual library 20060101

• Negative effect of heat sterilization on the free amino acid concentrations in infant formula.

  European journal of clinical nutrition 20060101

• Mechanisms for nitric oxide synthesis in plants.

  Journal of experimental botany 20060101

• A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination.

  Arthritis and rheumatism 20060101

• Smoking and rheumatoid arthritis: another reason to just say no.

  Arthritis and rheumatism 20060101

• Deletion of RTS1, encoding a regulatory subunit of protein phosphatase 2A, results in constitutive amino acid signaling via increased Stp1p processing.

  Eukaryotic cell 20060101

• Arginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthma.

  Respiratory research 20060101

• Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies.

  Lipids in health and disease 20060101

• Amino acids, arginase and nitric oxide in vascular health.

  Clinical and experimental pharmacology & physiology 20060101

• Activation of L-arginine transport in undialysed chronic renal failure and continuous ambulatory peritoneal dialysis patients.

  Clinical and experimental pharmacology & physiology 20060101

• Epigenetics and airways disease.

  Respiratory research 20060101

• Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case-control study.

  Arthritis research & therapy 20060101

• PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease.

  Arthritis research & therapy 20060101

• On the evolution of the standard amino-acid alphabet.

  Genome biology 20060101

• Anticholinesterase toxicity and oxidative stress.

  TheScientificWorldJournal 20060101

• Bicarbonate dialysis, unlike acetate-free biofiltration, triggers mediators of inflammation and apoptosis in endothelial and smooth muscle cells.

  Journal of nephrology 20060101

• Antibodies against transglutaminases, peptidylarginine deiminase and citrulline in rheumatoid arthritis--new pathways to epitope spreading.

  Clinical and experimental rheumatology 20060101

• High-performance liquid chromatography method with radiochemical detection for measurement of nitric oxide synthase, arginase, and arginine decarboxylase activities.

  Methods and findings in experimental and clinical pharmacology 20060101

• Epstein-Barr virus and rheumatoid arthritis: is there a link?

  Arthritis research & therapy 20060101

• [Citrulline extracellular level in the nucleus accumbens during acquisition and extinction of classical conditioned fear response with pain reinforcement].

  Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20060101

• Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells.

  BMC cell biology 20060101

• Overexpression of endothelial nitric oxide synthase suppresses features of allergic asthma in mice.

  Respiratory research 20060101

• A case study in pathway knowledgebase verification.

  BMC bioinformatics 20060101

• Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis.

  Arthritis research & therapy 20060101

• Age related profiles of free amino acids in human skeletal muscle.

  Neuro endocrinology letters 20060101

• Correction of endothelial dysfunction in diabetic female rats by tetrahydrobiopterin and chronic insulin.

  Journal of vascular research 20060101

• Arginine challenge unravels persistent disturbances of urea cycle and gluconeogenesis in abstinent alcoholics.

  Alcohol and alcoholism (Oxford, Oxfordshire) 20060101

• Gene expression profiling of lymphoblastoid cell lines from monozygotic twins discordant in severity of autism reveals differential regulation of neurologically relevant genes.

  BMC genomics 20060101

• Citrullination: a posttranslational modification in health and disease.

  The international journal of biochemistry & cell biology 20060101

• Arabidopsis mitochondria have two basic amino acid transporters with partially overlapping specificities and differential expression in seedling development.

  Biochimica et biophysica acta 20060101

• Phytoestrogen alpha-zearalanol antagonizes homocysteine-induced imbalance of nitric oxide/endothelin-1 and apoptosis in human umbilical vein endothelial cells.

  Cell biochemistry and biophysics 20060101

• Decreased systemic bioavailability of L-arginine in patients with cystic fibrosis.

  Respiratory research 20060101

• 55 kDa outer-membrane protein from short-chain fatty acids exposed Salmonella enterica serovar Typhi induces apoptosis in macrophages.

  Antonie van Leeuwenhoek 20060101

• Appearance of individual amino acid concentrations in arterial blood during steady-state infusions of different amino acid formulations to ICU patients in support of whole-body protein metabolism.

  JPEN. Journal of parenteral and enteral nutrition 20060101

• Brefeldin A decreases the activity of the general amino acid permease (GAP1) and the more specific systems for L-leucine uptake in Saccharomyces cerevisiae.

  Cellular & molecular biology letters 20060101

• Differential effects of curcumin on vasoactive factors in the diabetic rat heart.

  Nutrition & metabolism 20060101

• Diagnostic value of anti-human citrullinated fibrinogen ELISA and comparison with four other anti-citrullinated protein assays.

  Arthritis research & therapy 20060101

• Diagnostic value of antibodies against a modified citrullinated vimentin in rheumatoid arthritis.

  Arthritis research & therapy 20060101

• Endothelin signaling pathways in rat adrenal medulla.

  Cellular and molecular neurobiology 20060101

• An association of lower serum citrulline levels within 30 days of acute rejection in patients following small intestine transplantation.

  Transplantation proceedings 20060101

• Impact of hemorheological and endothelial factors on microcirculation.

  Advances in experimental medicine and biology 20060101

• Apolipoprotein E isoform-dependent dendritic recovery of hippocampal neurons following activation of innate immunity.

  Journal of neuroinflammation 20060101

• Presence of antibodies against cyclic citrullinated peptides in patients with 'rhupus': a cross-sectional study.

  Arthritis research & therapy 20060101

• Citrullinated filaggrin is decreased in oral keratinocytes in rheumatoid arthritis.

  Clinical and experimental rheumatology 20060101

• Septic shock is correlated with asymmetrical dimethyl arginine levels, which may be influenced by a polymorphism in the dimethylarginine dimethylaminohydrolase II gene: a prospective observational study.

  Critical care (London, England) 20060101

• Nitric oxide and neopterin in bipolar affective disorder.

  Neuropsychobiology 20060101

• The genetics of chronic obstructive pulmonary disease.

  Respiratory research 20060101

• Hierarchical amino acid utilization and its influence on fermentation dynamics: rifamycin B fermentation using Amycolatopsis mediterranei S699, a case study.

  Microbial cell factories 20060101

• [Change of the nitric oxide synthase activity after administration of neurotoxic compounds in mice].

  Acta pharmaceutica Hungarica 20060101

• Identification of novel citrullinated autoantigens of synovium in rheumatoid arthritis using a proteomic approach.

  Arthritis research & therapy 20060101

• Sensitivity to endothelin-1 is decreased in isolated livers of endothelial constitutive nitric oxide synthase knockout mice.

  Comparative hepatology 20060101

• Tracing immature myelin in acute disseminated encephalomyelitis.

  The Turkish journal of pediatrics 20060101

• The release of nitric oxide from S-nitrosothiols promotes angiogenesis.

  PloS one 20060101

• Regional age-related changes in neuronal nitric oxide synthase (nNOS), messenger RNA levels and activity in SAMP8 brain.

  BMC neuroscience 20060101

• Therapeutic use of citrulline in cardiovascular disease.

  Cardiovascular drug reviews 20060101

• Correlation between different components of synovial fluid and pathogenesis of rheumatic diseases.

  Romanian journal of internal medicine = Revue roumaine de medecine interne 20060101

• [Modern strategy of diagnostics and management of patients with rheumatoid arthritis].

  Polskie Archiwum Medycyny Wewnetrznej 20060101

• Endothelial dysfunction: Possible mechanisms and ways of correction.

  Experimental and clinical cardiology 20060101

• Clinical significance of anti-filaggrin antibody recognizing uncitrullinated filaggrin in rheumatoid arthritis.

  Experimental & molecular medicine 20051231

• Utilization of dried blood spot citrulline level as a noninvasive method for monitoring graft function following intestinal transplantation.

  Transplantation 20051227

• Reduced bactericidal activity and nitric oxide production in metallothionein-deficient macrophages in response to lipopolysaccharide stimulation.

  Toxicology 20051215

• Nitric oxide inhibition and the impact on renal nerve-mediated antinatriuresis and antidiuresis in the anaesthetized rat.

  The Journal of physiology 20051215

• Relationships of Cysteine and Lysine residues with the substrate binding site of the mitochondrial ornithine/citrulline carrier: an inhibition kinetic approach combined with the analysis of the homology structural model.

  Biochimica et biophysica acta 20051210

• Recent advances in the understanding of the role of nitric oxide in cardiovascular homeostasis.

  Pharmacology & therapeutics 20051201

• Vibrational spectral studies of L-citrullinium perchlorate.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051201

• Endothelial nitric oxide synthase expression in pulmonary capillary hemangiomatosis.

  Experimental and molecular pathology 20051201

• The use of yeast mitochondria to study the properties of wild-type and mutant human mitochondrial ornithine transporter.

  Molecular genetics and metabolism 20051201

• Protein arginine methyltransferases: guardians of the Arg?

  Trends in biochemical sciences 20051201

• 3'UTR/T polymorphism of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is associated with modified anti-platelet activity of atorvastatin in hypercholesterolemic subjects.

  Atherosclerosis 20051201

• Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4.

  American journal of human genetics 20051201

• Citrulline, Viagra and BiDil--bad medicine.

  Alternative medicine review : a journal of clinical therapeutic 20051201

• Arginine metabolism, pulmonary hypertension, and sickle cell disease.

  JAMA 20051116

• Exploring the redox reactions between heme and tetrahydrobiopterin in the nitric oxide synthases.

  Dalton transactions (Cambridge, England : 2003) 20051107

• Endotoxin can decrease isolated rat parotid acinar cell amylase secretion in a nitric oxide-independent manner.

  European journal of pharmacology 20051107

• Inducible nitric oxide synthase involvement in the mechanism of action of Saccharomyces boulardii in castor oil-induced diarrhoea in rats.

  Nitric oxide : biology and chemistry 20051101

• Almost all about citrulline in mammals.

  Amino acids 20051101

• Citrullination of fibronectin in rheumatoid arthritis synovial tissue.

  Rheumatology (Oxford, England) 20051101

• Keratinocyte growth factor ameliorates acute graft-versus-host disease in a novel nonmyeloablative haploidentical transplantation model.

  Bone marrow transplantation 20051101

• The immune response to citrullinated antigens in autoimmune diseases.

  Autoimmunity reviews 20051101

• Implications of treatment-induced mucosal barrier injury.

  Current opinion in oncology 20051101

• Metabolic fates of ammonia-N in ruminal epithelial and duodenal mucosal cells isolated from growing sheep.

  Journal of dairy science 20051101

• The devil in the details: the emerging role of anticitrulline autoimmunity in rheumatoid arthritis.

  Journal of immunology (Baltimore, Md. : 1950) 20051101

• Molecular targets of dietary polyphenols with anti-inflammatory properties.

  Yonsei medical journal 20051031

• Metformin treatment restores the altered microvascular reactivity in neonatal streptozotocin-induced diabetic rats increasing NOS activity, but not NOS expression.

  Life sciences 20051007

• Crystal structures representing the Michaelis complex and the thiouronium reaction intermediate of Pseudomonas aeruginosa arginine deiminase.

  The Journal of biological chemistry 20051007

• Intestinal renal metabolism of L-citrulline and L-arginine following enteral or parenteral infusion of L-alanyl-L-[2,15N]glutamine or L-[2,15N]glutamine in mice.

  American journal of physiology. Gastrointestinal and liver physiology 20051001

• PADI4 polymorphisms are not associated with rheumatoid arthritis in the Spanish population.

  Rheumatology (Oxford, England) 20051001

• Effects of acute ammonia toxicity on nitric oxide (NO), citrulline-NO cycle enzymes, arginase and related metabolites in different regions of rat brain.

  Neuroscience research 20051001

• Inflammatory response to mucosal barrier injury after myeloablative therapy in allogeneic stem cell transplant recipients.

  Bone marrow transplantation 20051001

• Shuffling ammonia between mitochondria and plastids during photorespiration.

  Trends in plant science 20051001

• Citrullination and autoimmune disease: 8th Bertine Koperberg meeting.

  Annals of the rheumatic diseases 20051001

• A randomised, double-blinded, placebo-controlled, pilot study of parenteral glutamine for allogeneic stem cell transplant patients.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20051001

• Effects of ADMA upon gene expression: an insight into the pathophysiological significance of raised plasma ADMA.

  PLoS medicine 20051001

• Metabolic derangements in deficiency of citrin, a liver-type mitochondrial aspartate-glutamate carrier.

  Hepatology research : the official journal of the Japan Society of Hepatology 20051001

• Purification and characterization of glutamate N-acetyltransferase involved in citrulline accumulation in wild watermelon.

  The FEBS journal 20051001

• Integrity and stability of the citrulline-arginine pathway in normal and tumour cell lines.

  Cancer letters 20050928

• Nitric oxide synthase inhibition affects sarcoplasmic reticulum Ca2+ release in skeletal muscle fibres from mouse.

  The Journal of physiology 20050915

• Influence of ethanol and low pH on arginine and citrulline metabolism in lactic acid bacteria from wine.

  Research in microbiology 20050901

• Molecular requirements of lignin-carbohydrate complexes for expression of unique biological activities.

  Phytochemistry 20050901

• Effect of vein graft harvesting on endothelial nitric oxide synthase and nitric oxide production.

  The Annals of thoracic surgery 20050901

• Anti-citrullinated protein/peptide antibodies (ACPA) in rheumatoid arthritis: specificity and relation with rheumatoid factor.

  Autoimmunity reviews 20050901

• Post-ischaemic mild hypothermia inhibits apoptosis in the penumbral region by reducing neuronal nitric oxide synthase activity and thereby preventing endothelin-1-induced hydroxyl radical formation.

  The European journal of neuroscience 20050901

• Nitric oxide in patients with chronic liver diseases.

  Romanian journal of gastroenterology 20050901

• [Pathophysiological significances of citrullinated proteins in geriatric diseases].

  Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20050901

• Transforming growth factor-beta receptors localize to caveolae and regulate endothelial nitric oxide synthase in normal human endothelial cells.

  The Biochemical journal 20050815

• A continuous spectrophotometric assay for dimethylarginine dimethylaminohydrolase.

  Analytical biochemistry 20050815

• Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis.

  Biochemistry 20050809

• Antibodies to citrullinated human fibrinogen (ACF) have diagnostic and prognostic value in early arthritis.

  Annals of the rheumatic diseases 20050801

• Lactobacillus plantarum ccl gene is non-essential, arginine-repressed and codes for a conserved protein in Firmicutes.

  Archives of microbiology 20050801

• Arginine deprivation and metabolomics: important aspects of intermediary metabolism in relation to the differential sensitivity of normal and tumour cells.

  Seminars in cancer biology 20050801

• Serum citrulline is a simple quantitative marker for small intestinal enterocytes mass and absorption function in short bowel patients.

  The Journal of surgical research 20050801

• Methylation of the guanidino group of arginine residues prevents citrullination by peptidylarginine deiminase IV.

  FEBS letters 20050801

• Nitric oxide in control of luminescence from hatchetfish (Argyropelecus hemigymnus) photophores.

  The Journal of experimental biology 20050801

• Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase as pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity.

  Arthritis and rheumatism 20050801

• Differential expression of nitric oxide synthases in human scalp epidermal and hair follicle pigmentary units: implications for regulation of melanogenesis.

  The British journal of dermatology 20050801

• Ornithine alpha-ketoglutarate metabolism in the healthy rat in the postabsorptive state.

  Metabolism: clinical and experimental 20050801

• Regulation of platelet guanylyl cyclase by collagen: evidence that Glycoprotein VI mediates platelet nitric oxide synthesis in response to collagen.

  Thrombosis and haemostasis 20050801

• Diagnostic value and clinical significance of anti-CCP in patients with advanced rheumatoid arthritis.

  Journal of the National Medical Association 20050801

• [Influence of L-arginine supplementation on the plasma amino acid spectrum in burn patients].

  Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20050801

• [Molecular abnormality in aging: its contribution to clinical pathology].

  Rinsho byori. The Japanese journal of clinical pathology 20050801

• [Influence of local administration of apomorphine on citrulline extracellular level in the striatum: participation of the dopamine D1 and D2 receptors].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20050801

• Anti-citrullinated collagen type I antibody is a target of autoimmunity in rheumatoid arthritis.

  Biochemical and biophysical research communications 20050729

• Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease.

  JAMA 20050706

• Citrullination preferentially proceeds in glomerular Bowman's capsule and increases in obstructive nephropathy.

  Kidney international 20050701

• Mode of action of a potentially important excretory--secretory product from Giardia lamblia in mice enterocytes.

  Parasitology 20050701

• The feeding route (enteral or parenteral) affects the plasma response of the dipetide Ala-Gln and the amino acids glutamine, citrulline and arginine, with the administration of Ala-Gln in preoperative patients.

  The British journal of nutrition 20050701

• Expression, purification, crystallization and preliminary X-ray crystallographic studies of a novel acetylcitrulline deacetylase from Xanthomonas campestris.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050701

• Regulation of endothelial argininosuccinate synthase expression and NO production by an upstream open reading frame.

  The Journal of biological chemistry 20050624

• Determination of citrulline in watermelon rind.

  Journal of chromatography. A 20050617

• Remission of hepatocellular carcinoma with arginine depletion induced by systemic release of endogenous hepatic arginase due to transhepatic arterial embolisation, augmented by high-dose insulin: arginase as a potential drug candidate for hepatocellular carcinoma.

  Cancer letters 20050616

• Proinflammatory liver and antiinflammatory intestinal mediators involved in portal hypertensive rats.

  Mediators of inflammation 20050609

• Citrullination of central nervous system proteins during the development of experimental autoimmune encephalomyelitis.

  The Journal of comparative neurology 20050606

• Expression of citrullinated proteins in murine experimental autoimmune encephalomyelitis.

  The Journal of comparative neurology 20050606

• NOS3 is involved in the increased protein and arginine metabolic response in muscle during early endotoxemia in mice.

  American journal of physiology. Endocrinology and metabolism 20050601

• Arginine synthesis does not occur during first-pass hepatic metabolism in the neonatal piglet.

  American journal of physiology. Endocrinology and metabolism 20050601

• Leflunomide reduces nitric oxide production in patients with active rheumatoid arthritis.

  International immunopharmacology 20050601

• Diagnostic performances of anti-cyclic citrullinated peptides antibody and antifilaggrin antibody in Korean patients with rheumatoid arthritis.

  Journal of Korean medical science 20050601

• A role for nitric oxide in sensory-induced neurogenesis in an adult insect brain.

  The European journal of neuroscience 20050601

• A deiminated viral peptide to detect antibodies in rheumatoid arthritis.

  Annals of the New York Academy of Sciences 20050601

• Association of anti-cyclic citrullinated peptide antibodies, anti-citrullin antibodies, and IgM and IgA rheumatoid factors with serological parameters of disease activity in rheumatoid arthritis.

  Annals of the New York Academy of Sciences 20050601

• Clinical utility of the anti-CCP assay: experiences with 700 patients.

  Annals of the New York Academy of Sciences 20050601

• Multiplexed immunoassay for detection of rheumatoid factors by FIDISTM technology.

  Annals of the New York Academy of Sciences 20050601

• Substrate specificity and novel selective inhibitors of TNF-alpha converting enzyme (TACE) from two-dimensional substrate mapping.

  Combinatorial chemistry & high throughput screening 20050601

• Reply to comment on: 'Assessment of nitric oxide biosynthesis and peroxynitrite formation within the central nervous system by measuring L-citrulline in the cerebrospinal fluid?'.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050525

• Determination of amino acids associated with cerebral ischaemia in rat brain microdialysates using narrowbore liquid chromatography and fluorescence detection.

  Journal of neuroscience methods 20050515

• Interaction between ArgR and AhrC controls regulation of arginine metabolism in Lactococcus lactis.

  The Journal of biological chemistry 20050513

• The role of mitochondrially bound arginase in the regulation of urea synthesis: studies with [U-15N4]arginine, isolated mitochondria, and perfused rat liver.

  The Journal of biological chemistry 20050506

• Neuronal nitric oxide synthase inhibition differentially affects oxytocin and vasopressin secretion in salt loaded rats.

  Neuroscience letters 20050506

• Molecules affecting myelin stability: a novel hypothesis regarding the pathogenesis of multiple sclerosis.

  Journal of neuroscience research 20050501

• Humoral immune response to citrullinated collagen type II determinants in early rheumatoid arthritis.

  European journal of immunology 20050501

• Anti-cyclic citrullinated peptide antibodies in patients with primary Sjögren's syndrome.

  Annals of the rheumatic diseases 20050501

• Regulation of the expression of peptidylarginine deiminase type II gene (PADI2) in human keratinocytes involves Sp1 and Sp3 transcription factors.

  The Journal of investigative dermatology 20050501

• Time course of gene expression of inflammatory mediators in rat lung after diesel exhaust particle exposure.

  Environmental health perspectives 20050501

• Nitric oxide modulates peristaltic muscle activity associated with fluid circulation in the sea pansy Renilla koellikeri.

  The Journal of experimental biology 20050501

• The ketogenic diet influences the levels of excitatory and inhibitory amino acids in the CSF in children with refractory epilepsy.

  Epilepsy research 20050501

• The effect of type-1 fimbrial immunization on gut pathophysiological response in rats infected with Salmonella enterica subsp. enterica serovar Typhimurium.

  Molecular and cellular biochemistry 20050501

• [A sensitive technique for determining citrulline for the purpose of in vivo monitoring of the nitrogen oxide production in the CHS].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20050501

• A designed synthetic analogue of 4-OT is specific for a non-natural substrate.

  Journal of the American Chemical Society 20050427

• Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes.

  Biochemistry 20050419

• Comparative metabonomics of differential hydrazine toxicity in the rat and mouse.

  Toxicology and applied pharmacology 20050415

• Fibrin deimination in synovial tissue is not specific for rheumatoid arthritis but commonly occurs during synovitides.

  Journal of immunology (Baltimore, Md. : 1950) 20050415

• A study of the metabolites of ischemia-reperfusion injury and selected amino acids in the liver using microdialysis during transplantation.

  Transplantation 20050415

• The role of NOS2 and NOS3 in renal protein and arginine metabolism during early endotoxemia in mice.

  American journal of physiology. Renal physiology 20050401

• Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease.

  Journal of neuroscience research 20050401

• Effectiveness of scaling and root planing versus modified Widman flap on nitric oxide synthase and arginase activity in patients with chronic periodontitis.

  Journal of periodontal research 20050401

• Brain neuronal nitric oxide synthase neuron-mediated sympathoinhibition is enhanced in hypertensive Dahl rats.

  Journal of hypertension 20050401

• Arginine supplementation does not enhance serum nitric oxide levels in elderly nursing home residents with pressure ulcers.

  Biological research for nursing 20050401

• Calcium/calmodulin-dependent nitric oxide synthase activity in the CNS of Aplysia californica: biochemical characterization and link to cGMP pathways.

  Journal of inorganic biochemistry 20050401

• Direct single cell determination of nitric oxide synthase related metabolites in identified nitrergic neurons.

  Journal of inorganic biochemistry 20050401

• Serum citrulline levels correlate with enteral tolerance and bowel length in infants with short bowel syndrome.

  The Journal of pediatrics 20050401

• Thyroid status and nitric oxide in rat arterial vessels.

  The Journal of endocrinology 20050401

• Peptidylarginine deiminase type 4, anticitrullinated peptide antibodies, and rheumatoid arthritis.

  Autoimmunity reviews 20050401

• Interaction of central Ang II and NO on the cardiac sympathetic afferent reflex in dogs.

  Autonomic neuroscience : basic & clinical 20050331

• [Rheumatoid arthritis: early detection may nip it in the bud].

  Nederlands tijdschrift voor geneeskunde 20050326

• Interaction of the endothelial nitric oxide synthase with the CAT-1 arginine transporter enhances NO release by a mechanism not involving arginine transport.

  The Biochemical journal 20050315

• Hypocitrullinemia in patients with MELAS: an insight into the 'MELAS paradox'.

  Journal of the neurological sciences 20050315

• Nitric oxide stimulates gamma-aminobutyric acid release and inhibits glycine release in retina.

  The Journal of comparative neurology 20050314

• The three nitric-oxide synthases differ in their kinetics of tetrahydrobiopterin radical formation, heme-dioxy reduction, and arginine hydroxylation.

  The Journal of biological chemistry 20050311

• Design, synthesis, and in vitro evaluation of dipeptide-based antibody minor groove binder conjugates.

  Journal of medicinal chemistry 20050310

• Effect of arginine loss in myelin basic protein, as occurs in its deiminated charge isoform, on mediation of actin polymerization and actin binding to a lipid membrane in vitro.

  Biochemistry 20050308

• Endogenous methylarginines modulate superoxide as well as nitric oxide generation from neuronal nitric-oxide synthase: differences in the effects of monomethyl- and dimethylarginines in the presence and absence of tetrahydrobiopterin.

  The Journal of biological chemistry 20050304

• The inhibition of antithrombin by peptidylarginine deiminase 4 may contribute to pathogenesis of rheumatoid arthritis.

  Rheumatology (Oxford, England) 20050301

• Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids.

  Molecular pharmacology 20050301

• Grr1p is required for transcriptional induction of amino acid permease genes and proper transcriptional regulation of genes in carbon metabolism of Saccharomyces cerevisiae.

  Current genetics 20050301

• Carbofuran-induced oxidative stress in slow and fast skeletal muscles: prevention by memantine and atropine.

  Toxicology 20050301

• Cognitive deficits in aged rats correlate with levels of L-arginine, not with nNOS expression or 3,4-DAP-evoked transmitter release in the frontoparietal cortex.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050301

• [Value of anti-cyclic citrullinated peptides antibodies in comparison with rheumatoid factor for rheumatoid arthritis diagnosis].

  Pathologie-biologie 20050301

• PAD: the smoking gun behind arginine methylation signaling?

  BioEssays : news and reviews in molecular, cellular and developmental biology 20050301

• IgG subclass distribution of the rheumatoid arthritis-specific autoantibodies to citrullinated fibrin.

  Clinical and experimental immunology 20050301

• Improvement of portal hypertension and hepatic blood flow in cirrhotic rats by oestrogen.

  European journal of clinical investigation 20050301

• High glucose rapidly activates the nitric oxide/cyclic nucleotide pathway in human platelets via an osmotic mechanism.

  Thrombosis and haemostasis 20050301

• Comparison of enzymatic properties between hPADI2 and hPADI4.

  Biochemical and biophysical research communications 20050204

• Evidence for the involvement of nitric oxide in 3,4-methylenedioxymethamphetamine-induced serotonin depletion in the rat brain.

  The Journal of pharmacology and experimental therapeutics 20050201

• Endostatin uncouples NO and Ca2+ response to bradykinin through enhanced O2*- production in the intact coronary endothelium.

  American journal of physiology. Heart and circulatory physiology 20050201

• Limited plasticity in T cell recognition of modified T cell receptor contact residues in MHC class II bound peptides.

  Molecular immunology 20050201

• Citrin deficiency presenting with ketotic hypoglycaemia and hepatomegaly in childhood.

  European journal of pediatrics 20050201

• Screening of bitterness-suppressing agents for quinine: the use of molecularly imprinted polymers.

  Journal of pharmaceutical sciences 20050201

• The soy isoflavone genistein induces a late but sustained activation of the endothelial nitric oxide-synthase system in vitro.

  British journal of pharmacology 20050201

• Peptidylarginine deiminase isoforms 1-3 are expressed in the epidermis and involved in the deimination of K1 and filaggrin.

  The Journal of investigative dermatology 20050201

• Sunscreen ingredients inhibit inducible nitric oxide synthase (iNOS): a possible biochemical explanation for the sunscreen melanoma controversy.

  Melanoma research 20050201

• Mechanism of inactivation of inducible nitric oxide synthase by amidines. Irreversible enzyme inactivation without inactivator modification.

  Journal of the American Chemical Society 20050126

• Thermodynamic and kinetic analysis of the nitrosyl, carbonyl, and dioxy heme complexes of neuronal nitric-oxide synthase. The roles of substrate and tetrahydrobiopterin in oxygen activation.

  The Journal of biological chemistry 20050114

• Diagnostic performance and predictive value of rheumatoid factor, anti-citrullinated peptide antibodies, and the HLA shared epitope for diagnosis of rheumatoid arthritis.

  Clinical chemistry 20050101

• Influence of vaccination on the nitric oxide response of gilthead seabream following infection with Photobacterium damselae subsp. piscicida.

  Fish & shellfish immunology 20050101

• Localization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis.

  Rheumatology (Oxford, England) 20050101

• L-citrulline immunoreactivity reveals nitric oxide production in the electromotor and electrosensory systems of the weakly electric fish, Apteronotus leptorhynchus.

  Brain, behavior and evolution 20050101

• Delta1-pyrroline-5-carboxylate synthase deficiency: neurodegeneration, cataracts and connective tissue manifestations combined with hyperammonaemia and reduced ornithine, citrulline, arginine and proline.

  European journal of pediatrics 20050101

• Monitoring myeloablative therapy-induced small bowel toxicity by serum citrulline concentration: a comparison with sugar permeability tests.

  Cancer 20050101

• Citrullinated proteins in rheumatoid arthritis.

  Frontiers in bioscience : a journal and virtual library 20050101

• Accessibility of endothelial and inducible nitric oxide synthase to the intracellular citrulline-arginine regeneration pathway.

  Biochemical pharmacology 20050101

• Diagnostic performance and predictive value of anti-citrullinated peptide antibodies for diagnosis of rheumatoid arthritis: toward more accurate detection?

  Clinical chemistry 20050101

• Highly selective inhibition of inducible nitric oxide synthase ameliorates experimental acute pancreatitis.

  Pancreas 20050101

• Effects of prolonged oral supplementation with l-arginine on blood pressure and nitric oxide synthesis in preeclampsia.

  European journal of clinical investigation 20050101

• Atorvastatin reduces platelet-oxidized-LDL receptor expression in hypercholesterolaemic patients.

  European journal of clinical investigation 20050101

• Supplemental enteral arginine is metabolized to ornithine in injured patients.

  The Journal of surgical research 20050101

• Effects of renal nerve stimulation on intrarenal blood flow in rats with intact or inactivated NO synthases.

  Acta physiologica Scandinavica 20050101

• Urea enhances the nerve growth factor-induced neuroprotective effect on cholinergic neurons in organotypic rat brain slices.

  Neuroscience 20050101

• Effect of bradykinin on nitric oxide production, urea synthesis and viability of rat hepatocyte cultures.

  BMC physiology 20050101

• Determination of sites citrullinated by peptidylarginine deiminase using 18O stable isotope labeling and mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20050101

• Two Japanese brothers with hereditary gamma-glutamyl transpeptidase deficiency.

  Journal of inherited metabolic disease 20050101

• The role of arginine in infection and sepsis.

  JPEN. Journal of parenteral and enteral nutrition 20050101

• Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis.

  Arthritis research & therapy 20050101

• Infiltration of the synovial membrane with macrophage subsets and polymorphonuclear cells reflects global disease activity in spondyloarthropathy.

  Arthritis research & therapy 20050101

• Amplification of autoimmune disease by infection.

  Arthritis research & therapy 20050101

• Arginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxation.

  Respiratory research 20050101

• Vascular ossification-calcification in metabolic syndrome, type 2 diabetes mellitus, chronic kidney disease, and calciphylaxis-calcific uremic arteriolopathy: the emerging role of sodium thiosulfate.

  Cardiovascular diabetology 20050101

• [Susceptibility genes in rheumatoid arthritis: peptidylarginine deiminase (PADI) type 4].

  Nihon rinsho. Japanese journal of clinical medicine 20050101

• Phenotype commitment in vascular smooth muscle cells derived from coronary atherosclerotic plaques: differential gene expression of endothelial nitric oxide synthase.

  European journal of histochemistry : EJH 20050101

• Modulating co-stimulation: a rational strategy in the treatment of rheumatoid arthritis?

  Arthritis research & therapy 20050101

• Paracrine modulation of androgen synthesis in rat leydig cells by nitric oxide.

  Journal of andrology 20050101

• Increased NO production in lysinuric protein intolerance.

  Journal of inherited metabolic disease 20050101

• Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity.

  Arthritis research & therapy 20050101

• Elevated plasma citrulline and arginine due to consumption of Citrullus vulgaris (watermelon).

  Journal of inherited metabolic disease 20050101

• Role of oxidative stress in female reproduction.

  Reproductive biology and endocrinology : RB&E 20050101

• Expression of inducible nitric oxide synthase is significantly correlated with expression of vascular endothelial growth factor and dendritic cell infiltration in patients with advanced gastric carcinoma.

  Oncology 20050101

• Anti-citrulline antibodies in psoriatic patients with and without arthritis.

  Acta dermato-venereologica 20050101

• Macrophages and cytokines in the early defence against herpes simplex virus.

  Virology journal 20050101

• mRNA expression and localization of bNOS, eNOS and iNOS in human cervix at preterm and term labour.

  Reproductive biology and endocrinology : RB&E 20050101

• Peptidylarginine deiminase 4 (PADI4) identified as a conformation-dependent autoantigen in rheumatoid arthritis.

  Scandinavian journal of rheumatology 20050101

• Peptidylarginine deiminase (PAD) is a mouse cortical granule protein that plays a role in preimplantation embryonic development.

  Reproductive biology and endocrinology : RB&E 20050101

• Ornithine aminotransferase deficiency: diagnostic difficulties in neonatal presentation.

  Journal of inherited metabolic disease 20050101

• Organic compatible solutes of halotolerant and halophilic microorganisms.

  Saline systems 20050101

• Contribution of nitric oxide-producing cells in normal and diabetic rat retina.

  Japanese journal of ophthalmology 20050101

• Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis.

  Arthritis research & therapy 20050101

• [Arginine and statins: relationship between the nitric oxide pathway and the atherosclerosis development].

  Annales de biologie clinique 20050101

• A rigorous method for multigenic families' functional annotation: the peptidyl arginine deiminase (PADs) proteins family example.

  BMC genomics 20050101

• Genome-wide single nucleotide polymorphism analyses of rheumatoid arthritis.

  Journal of autoimmunity 20050101

• Association between occupational exposure to mineral oil and rheumatoid arthritis: results from the Swedish EIRA case-control study.

  Arthritis research & therapy 20050101

• Identification of citrullinated alpha-enolase as a candidate autoantigen in rheumatoid arthritis.

  Arthritis research & therapy 20050101

• Does a positive anti-CCP test identify a distinct arthritis entity?

  Arthritis research & therapy 20050101

• Sex differences in frass production and weight change in Tenebrio molitor (Coleoptera) infected with cysticercoids of the tapeworm Hymenolepis diminuta (Cestoda).

  Journal of insect science (Online) 20050101

• Assessment of nitric oxide biosynthesis and peroxynitrite formation within the central nervous system by measuring L-citrulline in the cerebrospinal fluid?

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225

• Increased peptidylarginine deiminase type II in hypoxic astrocytes.

  Biochemical and biophysical research communications 20041224

• [Antibodies against citrullinated proteins--a breakthrough in rheumatologic diagnostics].

  Lakartidningen 20041209

• Anthelmintic efficacy of genistein, the active principle of Flemingia vestita (Fabaceae): alterations in the free amino acid pool and ammonia levels in the fluke, Fasciolopsis buski.

  Parasitology international 20041201

• Autoantibodies to citrullinated proteins in rheumatoid arthritis: clinical performance and biochemical aspects of an RA-specific marker.

  Clinica chimica acta; international journal of clinical chemistry 20041201

• Effects of ornithine on neutrophil (PMN) free amino acid and alpha-keto acid profiles and immune functions in vitro.

  Amino acids 20041201

• Citrulline increases arginine pools and restores nitrogen balance after massive intestinal resection.

  Gut 20041201

• Rheumatoid factor and anticitrullinated protein antibodies in rheumatoid arthritis: diagnostic value, associations with radiological progression rate, and extra-articular manifestations.

  Annals of the rheumatic diseases 20041201

• NOx and R-NOx: effects on drug metabolism.

  Current drug metabolism 20041201

• Efficient elimination of B-lineage lymphomas by anti-CD20-auristatin conjugates.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20041201

• Association of rheumatoid arthritis treatment response and disease duration with declines in serum levels of IgM rheumatoid factor and anti-cyclic citrullinated peptide antibody.

  Arthritis and rheumatism 20041201

• Capillary electrophoretic and micellar electrokinetic separations of asymmetric dimethyl-L-arginine and structurally related amino acids: quantitation in human plasma.

  Journal of separation science 20041201

• Alpha-Tocopherol and endothelial nitric oxide synthesis.

  Annals of the New York Academy of Sciences 20041201

• Phytoestrogen alpha-zearalanol antagonizes oxidized LDL-induced inhibition of nitric oxide production and stimulation of endothelin-1 release in human umbilical vein endothelial cells.

  Endocrine 20041201

• Effects of storage time and temperature on the concentration of ethyl carbamate and its precursors in wine.

  Food additives and contaminants 20041201

• Activation of endothelial nitric-oxide synthase by the p38 MAPK in response to black tea polyphenols.

  The Journal of biological chemistry 20041105

• Inhibitory effect of organotin compounds on rat neuronal nitric oxide synthase through interaction with calmodulin.

  Biochemical and biophysical research communications 20041105

• Time course of nitric oxide production after endotoxin challenge in mice.

  American journal of physiology. Endocrinology and metabolism 20041101

• Determination of arginine and asymmetric dimethylarginine (ADMA) in human plasma by liquid chromatography/mass spectrometry with the isotope dilution technique.

  Journal of mass spectrometry : JMS 20041101

• What precedes development of rheumatoid arthritis?

  Annals of the rheumatic diseases 20041101

• Glyceryl trinitrate may trigger endogenous nitric oxide production in patients with chronic tension-type headache.

  Cephalalgia : an international journal of headache 20041101

• Nitric oxide as putative second messenger in nerve-induced cervical gland secretion in the guinea-pig.

  Acta obstetricia et gynecologica Scandinavica 20041101

• The Influence of a load of L-arginine on serum amino acids and pancreatic apoptosis/proliferation and ATP levels in the rat.

  Pancreas 20041101

• Co-expression and modulation of neuronal and endothelial nitric oxide synthase in human endothelial cells.

  Journal of molecular and cellular cardiology 20041101

• Thrombus-induced endothelial dysfunction: Hemoglobin and fibrin decrease nitric oxide bioactivity without altering eNOS.

  The Journal of surgical research 20041101

• The presence of citrullinated proteins is not specific for rheumatoid synovial tissue.

  Arthritis and rheumatism 20041101

• Influence of dietary arginine on the anabolic effects of androgens.

  The Journal of endocrinology 20041101

• Association between cerebrospinal fluid levels of asymmetric dimethyl-L-arginine, an endogenous inhibitor of endothelial nitric oxide synthase, and cerebral vasospasm in a primate model of subarachnoid hemorrhage.

  Journal of neurosurgery 20041101

• Nitric oxide formation in the oropharyngeal tract: possible influence of cigarette smoking.

  Nitric oxide : biology and chemistry 20041101

• Clinical and pathophysiological significance of the autoimmune response to citrullinated proteins in rheumatoid arthritis.

  Joint, bone, spine : revue du rhumatisme 20041101

• [Determination of the antioxidant activity of potential scavengers of nitric oxide].

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20041101

• Alternative nitric oxide-producing substrates for NO synthases.

  Free radical biology & medicine 20041015

• Electrostatic interactions dominate the catalytic contribution of arg39 in 4-oxalocrotonate tautomerase.

  Journal of the American Chemical Society 20041013

• Human PAD4 regulates histone arginine methylation levels via demethylimination.

  Science (New York, N.Y.) 20041008

• Rheumatologic diagnostic serology: tests which test clinicians.

  The New Zealand medical journal 20041008

• Anti-cyclic citrullinated antibodies: complementary to IgM rheumatoid factor in the early diagnosis of rheumatoid arthritis.

  The New Zealand medical journal 20041008

• Molecular biology: no exception to reversibility.

  Nature 20041007

• Tumour cell growth in culture: dependence on arginine.

  Clinical science (London, England : 1979) 20041001

• The effect of divalent cations on neuronal nitric oxide synthase activity.

  Toxicological sciences : an official journal of the Society of Toxicology 20041001

• Role of adenosine transport in gestational diabetes-induced L-arginine transport and nitric oxide synthesis in human umbilical vein endothelium.

  The Journal of physiology 20041001

• Effects of citrin deficiency in the perinatal period: feasibility of newborn mass screening for citrin deficiency.

  Pediatric research 20041001

• Decrease of anti-cyclic citrullinated peptide antibodies and rheumatoid factor following anti-TNFalpha therapy (infliximab) in rheumatoid arthritis is associated with clinical improvement.

  Annals of the rheumatic diseases 20041001

• Inhibition of endothelial nitric oxide generation by low-density lipoprotein is partially prevented by L-arginine and L-ascorbate.

  Atherosclerosis 20041001

• Up-regulated neuronal nitric oxide synthase compensates coronary flow response to bradykinin in endothelial nitric oxide synthase-deficient mice.

  Journal of cardiovascular pharmacology 20041001

• Sepsis: an arginine deficiency state?

  Critical care medicine 20041001

• Cellular and physiological effects of arginine.

  Mini reviews in medicinal chemistry 20041001

• Regulation of the cellular and physiological effects of glutamine.

  Mini reviews in medicinal chemistry 20041001

• Histone deimination antagonizes arginine methylation.

  Cell 20040903

• Comparison of serum nitric oxide levels in active juvenile rheumatoid arthritis with those of patients in remission.

  Rheumatology international 20040901

• Alpha-tocopherol amplifies phosphorylation of endothelial nitric oxide synthase at serine 1177 and its short-chain derivative trolox stabilizes tetrahydrobiopterin.

  Free radical biology & medicine 20040901

• Aspirin induces nitric oxide release from vascular endothelium: a novel mechanism of action.

  British journal of pharmacology 20040901

• Nitric oxide synthase in acute alteration of nitric oxide levels after subarachnoid hemorrhage.

  Neurosurgery 20040901

• Plasma citrulline concentration: a surrogate end point for radiation-induced mucosal atrophy of the small bowel. A feasibility study in 23 patients.

  International journal of radiation oncology, biology, physics 20040901

• Substantial changes in central nervous system neurotransmitters and neuromodulators accompany phase change in the locust.

  The Journal of experimental biology 20040901

• Functional characterization of HUVEC-CS: Ca2+ signaling, ERK 1/2 activation, mitogenesis and vasodilator production.

  The Journal of endocrinology 20040901

• Biochemical responses of healthy subjects during dietary supplementation with L-arginine.

  The Journal of nutritional biochemistry 20040901

• Combined chronic treatment with citalopram and lithium does not modify the regional neurochemistry of nitric oxide in rat brain.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040901

• Effects of long-term inhibition of neuronal nitric oxide synthase (NOS1) in uninephrectomized diabetic rats.

  Nitric oxide : biology and chemistry 20040901

• Argininosuccinate synthetase is reversibly inactivated by S-nitrosylation in vitro and in vivo.

  The Journal of biological chemistry 20040827

• Regulation of regional lung perfusion by nitric oxide.

  American journal of respiratory and critical care medicine 20040815

• Pregnancy in a healthy woman with untreated citrullinemia.

  American journal of medical genetics. Part A 20040815

• Characterization of hydroxyl radical formation by microsomal enzymes using a water-soluble trap, terephthalate.

  Biochemical pharmacology 20040815

• Upregulation of endothelial nitric oxide synthase in rat aorta after ingestion of fish oil-rich diet.

  American journal of physiology. Heart and circulatory physiology 20040801

• Adaptative increase of ornithine production and decrease of ammonia metabolism in rat colonocytes after hyperproteic diet ingestion.

  American journal of physiology. Gastrointestinal and liver physiology 20040801

• Citrulline: a potentially simple quantitative marker of intestinal epithelial damage following myeloablative therapy.

  Bone marrow transplantation 20040801

• Primary metabolism in N2-fixing Alnus incana-Frankia symbiotic root nodules studied with 15N and 31P nuclear magnetic resonance spectroscopy.

  Planta 20040801

• Neuronal nitric oxide synthase (NNOS) catalyzes one-electron reduction of 2,4,6-trinitrotoluene, resulting in decreased nitric oxide production and increased nNOS gene expression: implication for oxidative stress.

  Free radical biology & medicine 20040801

• Structural basis for Ca(2+)-induced activation of human PAD4.

  Nature structural & molecular biology 20040801

• Role of nitric oxide pathway in hypotensive and renal effects of furosemide during extracellular volume expansion.

  Journal of hypertension 20040801

• Axonal degeneration and inflammation in acute optic neuritis.

  Journal of neurology, neurosurgery, and psychiatry 20040801

• Serum amino acids in patients with mutations in the hepatocyte nuclear factor-1 alpha gene.

  Diabetic medicine : a journal of the British Diabetic Association 20040801

• Arabidopsis thaliana GLN2-encoded glutamine synthetase is dual targeted to leaf mitochondria and chloroplasts.

  The Plant cell 20040801

• The joy of citrulline: new insights into the diagnosis, pathogenesis, and treatment of rheumatoid arthritis.

  The Journal of rheumatology 20040801

• Arginine deficiency in preterm infants: biochemical mechanisms and nutritional implications.

  The Journal of nutritional biochemistry 20040801

• Ischemia and reoxygenation induced amino acid release release and tissue damage in the slices of rat corpus striatum.

  Amino acids 20040801

• Protective effects of L-arginine on reperfusion injury after pancreaticoduodenal transplantation in rats.

  Hepatobiliary & pancreatic diseases international : HBPD INT 20040801

• Hyperammonemia with citrullinemia.

  Indian pediatrics 20040801

• Mitochondrial nitric-oxide synthase: enzyme expression, characterization, and regulation.

  Journal of bioenergetics and biomembranes 20040801

• Interstitial deletion of chromosome 2q32-34 associated with multiple congenital anomalies and a urea cycle defect (CPS I deficiency).

  American journal of medical genetics. Part A 20040730

• The role of carbon monoxide and nitric oxide in hyperosmolality-induced atrial natriuretic peptide release by hypothalamus in vitro.

  Brain research 20040730

• Liquid chromatographic-fluorimetric method for the estimation of nitric oxide biosynthesis in the central nervous system.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040705

• Induction of hyperammonia in irradiated hepatoma cells: a recapitulation and possible explanation of the phenomenon.

  British journal of cancer 20040705

• In vivo and in vitro evidence for ACh-stimulated L-arginine uptake.

  American journal of physiology. Heart and circulatory physiology 20040701

• Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells.

  Pflugers Archiv : European journal of physiology 20040701

• An analysis of the association between serum citrulline and acute rejection among 26 recipients of intestinal transplant.

  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040701

• Absence of citrulline-specific autoantibodies in animal models of autoimmunity.

  Arthritis and rheumatism 20040701

• Is nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease?

  Neurological research 20040701

• Reduced endothelial nitric oxide synthase activity and concentration in fetal umbilical veins from maternal cigarette smokers.

  American journal of obstetrics and gynecology 20040701

• Therapeutic strategies for rheumatoid arthritis.

  The New England journal of medicine 20040617

• Evidence for a metabolic shift of arginine metabolism in sickle cell disease.

  Annals of hematology 20040601

• Spin trapping of nitric oxide with the iron-dithiocarbamate complex: chemistry and biology.

  Antioxidants & redox signaling 20040601

• Acute reduction of circulating arginine in mice does not compromise whole body NO production.

  Clinical nutrition (Edinburgh, Scotland) 20040601

• The inhibition of retinal inducible nitric oxide synthase overexpression and the attenuation of experimental uveitis by anti-inflammatory drugs in rats.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040601

• Enterocyte metabolism during early adaptation after extensive intestinal resection in a rat model.

  Surgery 20040601

• Transcriptional profiling of extracellular amino acid sensing in Saccharomyces cerevisiae and the role of Stp1p and Stp2p.

  Yeast (Chichester, England) 20040601

• Prolonged exposure to intermittent alcohol vapors decreases the ACTH as well as hypothalamic nitric oxide and cytokine responses to endotoxemia.

  Alcoholism, clinical and experimental research 20040601

• Increased (E)-4-hydroxy-2-nonenal and asymmetric dimethylarginine concentrations and decreased nitric oxide concentrations in the plasma of patients with major depression.

  Journal of affective disorders 20040601

• A quantitative study of the neuronal nitric oxide synthase expression in the superficial layers of the adult rat superior colliculus after perinatal enucleation.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20040601

• Expression of neuronal nitric oxide synthase in the developing superficial layers of the rat superior colliculus.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040601

• Anti-CCP antibodies: the new rheumatoid factor in the serology of rheumatoid arthritis.

  Autoimmunity reviews 20040601

• Urea synthesis by ruminal epithelial and duodenal mucosal cells from growing sheep.

  Journal of dairy science 20040601

• Autoantibodies to citrullinated (poly)peptides: a key diagnostic and prognostic marker for rheumatoid arthritis.

  Autoimmunity 20040601

• Increased citrullinated glial fibrillary acidic protein in secondary progressive multiple sclerosis.

  The Journal of comparative neurology 20040517

• Autoantibodies as predictors of disease.

  Lancet (London, England) 20040508

• Arginine deiminase uses an active-site cysteine in nucleophilic catalysis of L-arginine hydrolysis.

  Journal of the American Chemical Society 20040505

• NOS2 deficiency increases intestinal metabolism both in nonstimulated and endotoxemic mice.

  American journal of physiology. Gastrointestinal and liver physiology 20040501

• Pertussis toxin activates L-arginine uptake in pulmonary endothelial cells through downregulation of PKC-alpha activity.

  American journal of physiology. Lung cellular and molecular physiology 20040501

• Clinical utility of anti-CCP antibodies in the differential diagnosis of elderly-onset rheumatoid arthritis and polymyalgia rheumatica.

  Rheumatology (Oxford, England) 20040501

• Activation of the nitric oxide response in gilthead seabream after experimental infection with Photobacterium damselae subsp. piscicida.

  Fish & shellfish immunology 20040501

• Diagnostic value of anticyclic citrullinated peptide antibody in rheumatoid arthritis.

  The Journal of rheumatology 20040501

• MSMA resistance studies.

  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20040501

• Argininosuccinate synthase expression is required to maintain nitric oxide production and cell viability in aortic endothelial cells.

  The Journal of biological chemistry 20040430

• A conserved Val to Ile switch near the heme pocket of animal and bacterial nitric-oxide synthases helps determine their distinct catalytic profiles.

  The Journal of biological chemistry 20040430

• Inhibition of insulin amyloid formation by small stress molecules.

  FEBS letters 20040423

• The urea cycle and related pathways in the liver of Walker-256 tumor-bearing rats.

  Biochimica et biophysica acta 20040405

• Structural insight into arginine degradation by arginine deiminase, an antibacterial and parasite drug target.

  The Journal of biological chemistry 20040402

• Unlocking the 'PAD' lock on rheumatoid arthritis.

  Annals of the rheumatic diseases 20040401

• Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages.

  Annals of the rheumatic diseases 20040401

• Evaluation of anti-citrullinated filaggrin antibodies as hallmarks for the diagnosis of rheumatic diseases.

  Annals of the rheumatic diseases 20040401

• Feasibility of auxiliary partial orthotopic liver transplantation from living donors for patients with adult-onset type II citrullinemia.

  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20040401

• Environmentally determined genetic expression: clinical correlates with molecular variants of carbamyl phosphate synthetase I.

  Molecular genetics and metabolism 20040401

• Problems in the management of urea cycle disorders.

  Molecular genetics and metabolism 20040401

• Crystal structures of arginine deiminase with covalent reaction intermediates; implications for catalytic mechanism.

  Structure (London, England : 1993) 20040401

• Attraction to amino acids by Lymnaea acuminata, the snail host of Fasciola species.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040401

• Clearance of amino acids by hemodialysis in argininosuccinate synthetase deficiency.

  The Journal of pediatrics 20040401

• Immune modulation of the pulmonary hypertensive response to bacterial lipopolysaccharide (endotoxin) in broilers.

  Poultry science 20040401

• Hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome with evidence of mitochondrial dysfunction due to a novel SLC25A15 (ORNT1) gene mutation in a Palestinian family.

  Journal of the neurological sciences 20040315

• Toxoplasma gondii lacks the enzymes required for de novo arginine biosynthesis and arginine starvation triggers cyst formation.

  International journal for parasitology 20040309

• Synthesis of nitric oxide in postganglionic myenteric neurons during endotoxemia: implications for gastric motor function in rats.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040301

• Application of the measurement of oxidized pyridine dinucleotides with high-performance liquid chromatography-fluorescence detection to assay the uncoupled oxidation of NADPH by neuronal nitric oxide synthase.

  Analytical biochemistry 20040301

• Simultaneous determination of arginine and seven metabolites in plasma by reversed-phase liquid chromatography with a time-controlled ortho-phthaldialdehyde precolumn derivatization.

  Analytical biochemistry 20040301

• Defining normal plasma citrulline in intestinal transplant recipients.

  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040301

• Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis: a prospective cohort study.

  Arthritis and rheumatism 20040301

• Trends in serum citrulline and acute rejection among recipients of small bowel transplants.

  Transplantation proceedings 20040301

• Effects of ACE inhibition and AT1-receptor blockade on haemodynamic responses to L-arginine in Type 1 diabetes.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20040301

• Application of the linear interaction energy method (LIE) to estimate the binding free energy values of Escherichia coli wild-type and mutant arginine repressor C-terminal domain (ArgRc)-l-arginine and ArgRc-l-citrulline protein-ligand complexes.

  Journal of molecular graphics & modelling 20040301

• Expression of DDAH1 in chick and rat embryos.

  Brain research. Developmental brain research 20040220

• Inducible nitric oxide synthase is involved in the mechanisms of cocaine enhanced neuronal apoptosis induced by HIV-1 gp120 in the neocortex of rat.

  Neuroscience letters 20040219

• Incidence and distribution of argininosuccinate synthetase deficiency in human cancers: a method for identifying cancers sensitive to arginine deprivation.

  Cancer 20040215

• Comparison between the influence of shocks and endotoxemia on the activation of brain cells that contain nitric oxide.

  Brain research 20040213

• Adenovirus gene transfer of recombinant endothelial nitric oxide synthase enhances contractile function in ventricular myocytes.

  Journal of cardiovascular pharmacology 20040201

• Relationship between carbamoyl-phosphate synthetase genotype and systemic vascular function.

  Hypertension (Dallas, Tex. : 1979) 20040201

• Nitric oxide is not involved in the control of vasopressin release during acute forced swimming in rats.

  Amino acids 20040201

• Preeclampsia is associated with loss of neuronal nitric oxide synthase expression in vascular smooth muscle cells of the human umbilical cord.

  Histopathology 20040201

• Specific autoantibodies precede the symptoms of rheumatoid arthritis: a study of serial measurements in blood donors.

  Arthritis and rheumatism 20040201

• Palmitate increases nitric oxide synthase activity that is involved in palmitate-induced cell death in cardiomyocytes.

  Nitric oxide : biology and chemistry 20040201

• Role of the W07-toxin on Vibrio cholerae-induced diarrhoea.

  Biochimica et biophysica acta 20040105

• Expression analysis of putative arcA, arcB and arcC genes partially cloned from Lactobacillus plantarum isolated from wine.

  Journal of applied microbiology 20040101

• Autoantibodies recognizing citrullinated rat filaggrin in an ELISA using citrullinated and non-citrullinated recombinant proteins as antigens are highly diagnostic for rheumatoid arthritis.

  Clinical and experimental immunology 20040101

• Expression of nitric oxide synthase and effect of substrate manipulation of the nitric oxide pathway in mouse ovarian follicles.

  Human reproduction (Oxford, England) 20040101

• Metabolic changes induced by ischemia and cardioplegia: a study employing cardiac microdialysis in pigs.

  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20040101

• Arginine increases growth hormone gene expression in rat pituitary and GH3 cells.

  Neuroendocrinology 20040101

• IL-10 inhibits nitric oxide synthesis in murine uterus.

  Neuroimmunomodulation 20040101

• Role of nitric oxide concentrations on human sperm motility.

  Journal of andrology 20040101

• Is the celiac disease model relevant to rheumatoid arthritis?

  Joint, bone, spine : revue du rhumatisme 20040101

• Antiproliferative and apoptotic effects of selective phenolic acids on T47D human breast cancer cells: potential mechanisms of action.

  Breast cancer research : BCR 20040101

• Nitric oxide synthetic capacity in relation to dialysate temperature.

  Blood purification 20040101

• Anti-Sa antibodies: prognostic and pathogenetic significance to rheumatoid arthritis.

  Arthritis research & therapy 20040101

• Role of anti-cyclic citrullinated peptide antibodies in discriminating patients with rheumatoid arthritis from patients with chronic hepatitis C infection-associated polyarticular involvement.

  Arthritis research & therapy 20040101

• Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin.

  Arthritis research & therapy 20040101

• The synovial proteome: analysis of fibroblast-like synoviocytes.

  Arthritis research & therapy 20040101

• Suppression of nitric oxide production in mouse macrophages by soybean flavonoids accumulated in response to nitroprusside and fungal elicitation.

  BMC biochemistry 20040101

• Homocysteine and reactive oxygen species in metabolic syndrome, type 2 diabetes mellitus, and atheroscleropathy: the pleiotropic effects of folate supplementation.

  Nutrition journal 20040101

• Citrullinated proteins: sparks that may ignite the fire in rheumatoid arthritis.

  Arthritis research & therapy 20040101

• Nitric oxide and hemodialysis.

  Seminars in dialysis 20040101

• Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13.

  Journal of human genetics 20040101

• History and diagnostic value of antibodies to citrullinated proteins in rheumatoid arthritis.

  International journal of immunopathology and pharmacology 20040101

• Harmaline-induced climbing fiber activation causes amino acid and peptide release in the rodent cerebellar cortex and a unique temporal pattern of Fos expression in the olivo-cerebellar pathway.

  Journal of neurocytology 20040101

• Measurement of nitric oxide synthase activity in vivo and in vitro by gas chromatography-mass spectrometry.

  Methods in molecular biology (Clifton, N.J.) 20040101

• A nonradioactive assay for nitric oxide synthase activity in tissue extracts.

  Methods in molecular biology (Clifton, N.J.) 20040101

• Amino acid neurotransmitter release and learning: a study of visual imprinting.

  Neuroscience 20040101

• Positive N-methyl-D-aspartate receptor modulation by selective glycine transporter-1 inhibition in the rat dorsal spinal cord in vivo.

  Neuroscience 20040101

• A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis.

  Arthritis research & therapy 20040101

• Citrullination of self-proteins and autoimmunity.

  Scandinavian journal of immunology 20040101

• Endothelium and hemorheology.

  Clinical hemorheology and microcirculation 20040101

• The role of nitric oxide in the pathogenesis of brain lesions during the development of Alzheimer's disease.

  In vivo (Athens, Greece) 20040101

• Clastogenic but not apoptotic effects on human artery endothelial cells by concentrations of inorganic lead inhibiting their nitric oxide production.

  International journal of immunopathology and pharmacology 20040101

• The two faces of endothelial nitric oxide synthase in the pathophysiology of atherosclerosis.

  Endothelium : journal of endothelial cell research 20040101

• Orotic aciduria and plasma urea cycle-related amino acid alterations in short bowel syndrome, evoked by an arginine-free diet.

  JPEN. Journal of parenteral and enteral nutrition 20040101

• A scavenger role for nitric oxide in the aged rat kidney.

  International journal of immunopathology and pharmacology 20040101

• Oxidation in rheumatoid arthritis.

  Arthritis research & therapy 20040101

• Autoantibodies in normals--the value of predicting rheumatoid arthritis.

  Arthritis research & therapy 20040101

• Age-related changes of insulin receptors, plasma insulin and glucose level.

  Biogerontology 20040101

• Citrulline can preserve proliferation and prevent the loss of CD3 zeta chain under conditions of low arginine.

  JPEN. Journal of parenteral and enteral nutrition 20040101

• A neonatal case of citrullinemia with urolithiasis.

  Annals of Saudi medicine 20040101

• Metabolic and hematological effects of dietary supplementation with arginine on rats bearing ascitic Walker 256 tumor.

  Annals of nutrition & metabolism 20040101

• cDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type VI.

  Acta biochimica Polonica 20040101

• Arginine metabolism during macrophage autocrine activation and infection with mouse hepatitis virus 3.

  Immunobiology 20040101

• Clinical improvement and serum amino acid levels after mud-bath therapy.

  International journal of clinical pharmacology research 20040101

• [Antibodies to cyclic citrullinized peptide in rheumatoid arthritis].

  Terapevticheskii arkhiv 20040101

• [Biocompatibility of the acetate in the dialysis fluid].

  Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20040101

• Modulation of the L-arginine/nitric oxide signalling pathway in vascular endothelial cells.

  Biochemical Society symposium 20040101

• The ergogenic potential of arginine.

  Journal of the International Society of Sports Nutrition 20040101

• Structural elements contribute to the calcium/calmodulin dependence on enzyme activation in human endothelial nitric-oxide synthase.

  The Journal of biological chemistry 20031226

• Simultaneous detection of arginine, asymmetric dimethylarginine, symmetric dimethylarginine and citrulline in human plasma and urine applying liquid chromatography-mass spectrometry with very straightforward sample preparation.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031225

• Inhibition of human colon carcinoma cell growth by ammonia: a non-cytotoxic process associated with polyamine synthesis reduction.

  Biochimica et biophysica acta 20031205

• Long-term outcome of patients with urea cycle disorders and the question of neonatal screening.

  European journal of pediatrics 20031201

• Crystallization and preliminary X-ray crystallographic analysis of human peptidylarginine deiminase V.

  Acta crystallographica. Section D, Biological crystallography 20031201

• ADMA: a novel risk factor that explains excess cardiovascular event rate in patients with end-stage renal disease.

  Atherosclerosis. Supplements 20031201

• Reduction of nilutamide by NO synthases: implications for the adverse effects of this nitroaromatic antiandrogen drug.

  Chemical research in toxicology 20031201

• Value of antibodies to citrulline-containing peptides for diagnosing early rheumatoid arthritis.

  The Journal of rheumatology 20031201

• Evaluation of oxidative stress after fractures. A preliminary study.

  Acta orthopaedica Belgica 20031201

• NO inhibition of the magnocellular neuroendocrine system in rats is independent of cGMP signaling pathway.

  Experimental neurology 20031201

• [Adult-onset type II citrullinemia].

  No to shinkei = Brain and nerve 20031201

• A tetrahydrobiopterin radical forms and then becomes reduced during Nomega-hydroxyarginine oxidation by nitric-oxide synthase.

  The Journal of biological chemistry 20031121

• Ability of tetrahydrobiopterin analogues to support catalysis by inducible nitric oxide synthase: formation of a pterin radical is required for enzyme activity.

  Biochemistry 20031118

• Citrulline: a physiologic marker enabling quantitation and monitoring of epithelial radiation-induced small bowel damage.

  International journal of radiation oncology, biology, physics 20031115

• Recombinant arginine deiminase as a differential modulator of inducible (iNOS) and endothelial (eNOS) nitric oxide synthetase activity in cultured endothelial cells.

  Biochemical pharmacology 20031115

• [Autoantibodies in the diagnosis of rheumatoid arthritis. Utility of anti-cyclic citrullinated peptides].

  Medicina clinica 20031108

• Synthesis of potent CXCR4 inhibitors possessing low cytotoxicity and improved biostability based on T140 derivatives.

  Organic & biomolecular chemistry 20031107

• Time-dependence and preliminary SAR studies in inhibition of nitric oxide synthase isoforms by homologues of thiocitrulline.

  Bioorganic & medicinal chemistry letters 20031103

• Up-regulation of endothelial nitric-oxide synthase by endothelium-derived hyperpolarizing factor involves mitogen-activated protein kinase and protein kinase C signaling pathways.

  The Journal of pharmacology and experimental therapeutics 20031101

• Globular adiponectin upregulates nitric oxide production in vascular endothelial cells.

  Diabetologia 20031101

• PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease.

  BioEssays : news and reviews in molecular, cellular and developmental biology 20031101

• Effects of angiotensin II on nitric oxide generation in growing and resting rat aortic endothelial cells.

  Journal of hypertension 20031101

• Peptidylarginine deiminase type 4: identification of a rheumatoid arthritis-susceptible gene.

  Trends in molecular medicine 20031101

• The Gap1 general amino acid permease acts as an amino acid sensor for activation of protein kinase A targets in the yeast Saccharomyces cerevisiae.

  Molecular microbiology 20031101

• Identification and metabolic role of the mitochondrial aspartate-glutamate transporter in Saccharomyces cerevisiae.

  Molecular microbiology 20031101

• A decrease in glucose production is associated with an increase in plasma citrulline response to oral arginine in normal volunteers.

  Metabolism: clinical and experimental 20031101

• Association of asymmetric dimethylarginine and endothelial dysfunction.

  Clinical chemistry and laboratory medicine 20031101

• Mild citrullinemia in Caucasians is an allelic variant of argininosuccinate synthetase deficiency (citrullinemia type 1).

  Molecular genetics and metabolism 20031101

• Role of neutral amino acid transport and protein breakdown for substrate supply of nitric oxide synthase in human endothelial cells.

  Circulation research 20031031

• Inhibitors of nitric oxide synthase block carbon monoxide-induced increases in cGMP in retina.

  Brain research 20031024

• Trichohyalin mechanically strengthens the hair follicle: multiple cross-bridging roles in the inner root shealth.

  The Journal of biological chemistry 20031017

• Functional expression of endothelial nitric oxide synthase fused to green fluorescent protein in transgenic mice.

  The American journal of pathology 20031001

• Endocrinology: nitric oxide-mediated insulin secretion in response to citrulline in islet beta-cells.

  Pancreas 20031001

• Depletion of serum L-arginine in patients with acute pancreatitis.

  Pancreas 20031001

• Simplified method to assay total plasma peroxidase activity and ferriheme products in sickle cell anemia, with initial results in assessing clinical severity in a trial with citrulline therapy.

  Journal of pediatric hematology/oncology 20031001

• The emerging role of asymmetric dimethylarginine as a novel cardiovascular risk factor.

  Cardiovascular research 20031001

• Constitutive and hyperresponsive signaling by mutant forms of Saccharomyces cerevisiae amino acid sensor Ssy1.

  Eukaryotic cell 20031001

• Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis.

  Arthritis and rheumatism 20031001

• Inducible nitric oxide synthase (NOS II) is constitutive in human neutrophils.

  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20031001

• Down-regulation of CYP1A2 induction during the maturation of mouse cerebellar granule cells in culture: role of nitric oxide accumulation.

  The European journal of neuroscience 20031001

• Plasma amino acids in ecstasy users.

  Neuro endocrinology letters 20031001

• [New diagnostic tests for rheumatoid arthritis].

  Rinsho byori. The Japanese journal of clinical pathology 20031001

• [A new marker for the diagnosis of rheumatoid arthritis: cyclic citrullinated peptide antibodies (anti-CCP)].

  Mikrobiyoloji bulteni 20031001

• Heat shock protein 90 as an endogenous protein enhancer of inducible nitric-oxide synthase.

  The Journal of biological chemistry 20030919

• The potential of dairy lactic acid bacteria to metabolise amino acids via non-transaminating reactions and endogenous transamination.

  International journal of food microbiology 20030915

• Role of ascorbate in the regulation of nitric oxide generation by polymorphonuclear leukocytes.

  Biochemical and biophysical research communications 20030912

• Clinical utility of the anti-CCP assay in patients with rheumatic diseases.

  Annals of the rheumatic diseases 20030901

• Brain nitric oxide synthase activity in spontaneously hypertensive rats during the development of hypertension.

  Journal of hypertension 20030901

• Arginine deiminase: a potential inhibitor of angiogenesis and tumour growth.

  British journal of cancer 20030901

• N-acetylglucosamine-inducible CaGAP1 encodes a general amino acid permease which co-ordinates external nitrogen source response and morphogenesis in Candida albicans.

  Microbiology (Reading, England) 20030901

• Platelet hyperactivity after statin treatment discontinuation.

  Thrombosis and haemostasis 20030901

• Role of L-citrulline transport in nitric oxide synthesis in rat aortic smooth muscle cells activated with LPS and interferon-gamma.

  British journal of pharmacology 20030901

• Another measurement of the elusive entity called 'intestinal function'.

  Journal of pediatric gastroenterology and nutrition 20030901

• Citrullination of synovial proteins in murine models of rheumatoid arthritis.

  Arthritis and rheumatism 20030901

• Inhibitory effects and spectral interactions of isomeric methoxyindazoles on recombinant nitric oxide synthases.

  Nitric oxide : biology and chemistry 20030901

• Chronic administration of losartan reverses cardiovascular changes in hypertensive fructose-fed rats.

  Cellular and molecular biology (Noisy-le-Grand, France) 20030901

• The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms.

  The Journal of biological chemistry 20030829

• cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity.

  Blood 20030815

• Prevention of kainic acid seizures-induced changes in levels of nitric oxide and high-energy phosphates by 7-nitroindazole in rat brain regions.

  Brain research 20030815

• Anti-cyclic citrullinated peptide antibodies in advanced rheumatoid arthritis.

  Annals of internal medicine 20030805

• Arginine deprivation, growth inhibition and tumour cell death: 3. Deficient utilisation of citrulline by malignant cells.

  British journal of cancer 20030804

• Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethylarginine dimethylaminohydrolase.

  Arteriosclerosis, thrombosis, and vascular biology 20030801

• Phenotype modulation in cultures of vascular smooth muscle cells from diabetic rats: association with increased nitric oxide synthase expression and superoxide anion generation.

  Journal of cellular physiology 20030801

• Aspirin protects endothelial cells from oxidant damage via the nitric oxide-cGMP pathway.

  Arteriosclerosis, thrombosis, and vascular biology 20030801

• Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis.

  Nature genetics 20030801

• European collaboration at its best: 23rd European Workshop for Rheumatology Research.

  Annals of the rheumatic diseases 20030801

• Exogenous biopterins requirement for iNOS function in vascular smooth muscle cells.

  Journal of cardiovascular pharmacology 20030801

• Defects in the regulation of B cell apoptosis are required for the production of citrullinated peptide autoantibodies in mice.

  Arthritis and rheumatism 20030801

• The predictive value of anti-cyclic citrullinated peptide antibodies in early arthritis.

  The Journal of rheumatology 20030801

• Recombinant human monoclonal autoantibodies specific for citrulline-containing peptides from phage display libraries derived from patients with rheumatoid arthritis.

  The Journal of rheumatology 20030801

• Inhibition of neural nitric oxide synthase attenuates the chloride secretory response to stroking in human jejunum.

  Surgery 20030801

• Cloning and characterization of human ORNT2: a second mitochondrial ornithine transporter that can rescue a defective ORNT1 in patients with the hyperornithinemia-hyperammonemia-homocitrullinuria syndrome, a urea cycle disorder.

  Molecular genetics and metabolism 20030801

• [Anti-citrulline antibodies in rheumatoid arthritis; diagnostic and prognostic values].

  Polskie Archiwum Medycyny Wewnetrznej 20030801

• Characterization of suppression of nitric oxide production by carbon monoxide poisoning in the striatum of free-moving rats, as determined by in vivo brain microdialysis.

  Brain research 20030725

• Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1*0401 MHC class II molecule.

  Journal of immunology (Baltimore, Md. : 1950) 20030715

• Impairment of vascular endothelial nitric oxide synthase activity by advanced glycation end products.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030701

• Nitric oxide pathway and response to nitroglycerin in cluster headache patients: plasma nitrite and citrulline levels.

  Cephalalgia : an international journal of headache 20030701

• High glucose-induced tyrosine nitration in endothelial cells: role of eNOS uncoupling and aldose reductase activation.

  Investigative ophthalmology & visual science 20030701

• Interaction of the 18.5-kD isoform of myelin basic protein with Ca2+ -calmodulin: effects of deimination assessed by intrinsic Trp fluorescence spectroscopy, dynamic light scattering, and circular dichroism.

  Protein science : a publication of the Protein Society 20030701

• Aspirin modifies nitric oxide synthase activity in platelets: effects of acute versus chronic aspirin treatment.

  Cardiovascular research 20030701

• Diagnostic value of anti-cyclic citrullinated Peptide antibody in patients with rheumatoid arthritis.

  The Journal of rheumatology 20030701

• Oral supplementation corrects plasma lysine concentrations in lysinuric protein intolerance.

  Metabolism: clinical and experimental 20030701

• Comparative regional haemodynamic effects of the nitric oxide synthase inhibitors, S-methyl-L-thiocitrulline and L-NAME, in conscious rats.

  British journal of pharmacology 20030701

• Liver transplantation as treatment for neurological disorders.

  Expert review of neurotherapeutics 20030701

• Structures of argininosuccinate synthetase in enzyme-ATP substrates and enzyme-AMP product forms: stereochemistry of the catalytic reaction.

  The Journal of biological chemistry 20030620

• Neonatal screening for citrullinaemia.

  European journal of pediatrics 20030601

• Neuroprotective kappa-opioid receptor agonist BRL 52537 attenuates ischemia-evoked nitric oxide production in vivo in rats.

  Stroke 20030601

• Degradation of arginine and other amino acids by butyrate-producing asaccharolytic anaerobic Gram-positive rods in periodontal pockets.

  Archives of oral biology 20030601

• The caveolar nitric oxide synthase/arginine regeneration system for NO production in endothelial cells.

  The Journal of experimental biology 20030601

• Serum amino acid concentrations in aging men and women.

  Amino acids 20030601

• Nitric oxide synthase activity in Fasciola hepatica: a radiometric study.

  Parasitology 20030601

• Influence of dietary arginine on sexual dimorphism of arginine metabolism in mice.

  The Journal of nutritional biochemistry 20030601

• Peroxynitrite and mitochondrial dysfunction in the pathogenesis of Parkinson's disease.

  Antioxidants & redox signaling 20030601

• The enhanced spontaneous activity of the diabetic colon is not the consequence of impaired inhibitory control mechanisms.

  Autonomic & autacoid pharmacology 20030601

• Purification and characterization of nitric oxide synthase from Staphylococcus aureus.

  FEMS microbiology letters 20030528

• Serial diffusion-weighted magnetic resonance imaging in adult-onset citrullinaemia.

  Journal of the neurological sciences 20030515

• Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells.

  Free radical biology & medicine 20030515

• Immunohistochemical localization of citrullinated proteins in adult rat brain.

  The Journal of comparative neurology 20030505

• Developmental changes of amino acids in ovine fetal fluids.

  Biology of reproduction 20030501

• Modulation of baroreceptor activity by gene transfer of nitric oxide synthase to carotid sinus adventitia.

  American journal of physiology. Regulatory, integrative and comparative physiology 20030501

• Gene transfer of endothelial nitric oxide synthase partially restores nitric oxide synthesis and erectile function in streptozotocin diabetic rats.

  The Journal of urology 20030501

• Cyanide binding study of neuronal nitric oxide synthase: effects of inhibitors and mutations at the substrate binding site.

  Journal of inorganic biochemistry 20030501

• Argininosuccinate synthetase from the urea cycle to the citrulline-NO cycle.

  European journal of biochemistry 20030501

• Anti-cyclic citrullinated peptide antibodies, IgM and IgA rheumatoid factors in the diagnosis and prognosis of rheumatoid arthritis.

  Rheumatology (Oxford, England) 20030501

• Changing pattern of deiminated proteins in developing human epidermis.

  The Journal of investigative dermatology 20030501

• Plasma citrulline: A marker of enterocyte mass in villous atrophy-associated small bowel disease.

  Gastroenterology 20030501

• Low endotoxemia prevents the reduction of gastric blood flow induced by NSAIDs: role of nitric oxide.

  British journal of pharmacology 20030501

• Species-specific modulation of the nitric oxide pathway after acute experimentally induced endotoxemia.

  Critical care medicine 20030501

• A novel method for measuring serum ornithine carbamoyltransferase.

  Annals of clinical biochemistry 20030501

• Release of pro-inflammatory mediators during myocardial ischemia/reperfusion in coronary artery bypass graft surgery.

  Molecular and cellular biochemistry 20030501

• Fever induced by platelet-derived growth factor, in contrast to fever induced by lipopolysaccharide, depends only on nitric oxide, but not on carbon monoxide pathway.

  European journal of pharmacology 20030425

• [Early diagnosis of rheumatoid arthritis with a test based upon a specific antigen: cyclic citrullinated peptide].

  Nederlands tijdschrift voor geneeskunde 20030412

• Recent findings on natural products with erectile-dysfunction activity.

  Phytochemistry 20030401

• L-arginine supplementation accelerates renal fibrosis and shortens life span in experimental lupus nephritis.

  Kidney international 20030401

• Chemical modification of the mitochondrial ornithine/citrulline carrier by SH reagents: effects on the transport activity and transition from carrier to pore-like function.

  Biochimica et biophysica acta 20030401

• [Severe fulminant form of neonatal citrullinemia. Report of a case].

  Revista de neurologia 20030401

• Anti-cyclic citrullinated peptide (anti-CCP) antibodies in children with juvenile idiopathic arthritis.

  The Journal of rheumatology 20030401

• Computational docking of L-arginine and its structural analogues to C-terminal domain of Escherichia coli arginine repressor protein (ArgRc).

  Journal of molecular modeling 20030401

• [NO (nitric oxide) and its significance in regulation of vascular homeostasis].

  Vnitrni lekarstvi 20030401

• Selective stabilization of the chorismate mutase transition state by a positively charged hydrogen bond donor.

  Journal of the American Chemical Society 20030319

• Resistance to the anti-proliferative activity of recombinant arginine deiminase in cell culture correlates with the endogenous enzyme, argininosuccinate synthetase.

  Cancer letters 20030310

• Spectroscopic characterization of five- and six-coordinate ferrous-NO heme complexes. Evidence for heme Fe-proximal cysteinate bond cleavage in the ferrous-NO adducts of the Trp-409Tyr/Phe proximal environment mutants of neuronal nitric oxide synthase.

  Biochemistry 20030304

• Metabolism of asymmetric dimethylarginines is regulated in the lung developmentally and with pulmonary hypertension induced by hypobaric hypoxia.

  Circulation 20030304

• Effect of arginine, ornithine and citrulline supplementation upon performance and metabolism of trained rats.

  Cell biochemistry and function 20030301

• Filaggrin related antibodies among the aged.

  Annals of the rheumatic diseases 20030301

• Biphasic role of dopamine on female sexual behaviour via D2 receptors in the mediobasal hypothalamus.

  Neuropharmacology 20030301

• Effects of beta-adrenoceptor stimulation on endothelial nitric-oxide synthase phosphorylation of human umbilical vein endothelial cells.

  Acta pharmacologica Sinica 20030301

• Nitric oxide synthesis in human nonpregnant myometrium and uterine myomas.

  Fertility and sterility 20030301

• Gender differences in ET and NOS systems in ETB receptor-deficient rats: effect of a high salt diet.

  Hypertension (Dallas, Tex. : 1979) 20030301

• Role of endogenous nitric oxide in unilateral ureteropelvic junction obstruction in children.

  Kidney international 20030301

• Identification of a mitochondrial transporter for basic amino acids in Arabidopsis thaliana by functional reconstitution into liposomes and complementation in yeast.

  The Plant journal : for cell and molecular biology 20030301

• The diagnosis and prognosis of early arthritis: comment on the editorial by Scott.

  Arthritis and rheumatism 20030301

• Anti-cyclic citrullinated peptide antibody in early rheumatoid arthritis: comment on the editorial by Scott.

  Arthritis and rheumatism 20030301

• Arginine as an adjuvant to chemotherapy improves clinical outcome in active tuberculosis.

  The European respiratory journal 20030301

• Effect of acute ozone exposure on locomotor behavior and striatal function.

  Pharmacology, biochemistry, and behavior 20030301

• Treatment of ammonia intoxication in rats with urea cycle amino acids, furosemide and fluids.

  Veterinary and human toxicology 20030301

• [Anti-cyclic citrullinated peptide antibodies as a diagnostic test for rheumatoid arthritis].

  Harefuah 20030301

• Arginine deprivation, growth inhibition and tumour cell death: 2. Enzymatic degradation of arginine in normal and malignant cell cultures.

  British journal of cancer 20030224

• Changes in the ornithine cycle following ionising radiation cause a cytotoxic conditioning of the culture medium of H35 hepatoma cells.

  British journal of cancer 20030210

• Anticitrullinated protein/peptide antibody assays in early rheumatoid arthritis for predicting five year radiographic damage.

  Annals of the rheumatic diseases 20030201

• Gene expression and activity of enzymes in the arginine biosynthetic pathway in porcine fetal small intestine.

  Pediatric research 20030201

• Plasma urea-cycle-related amino acids, ammonium levels, and urinary orotic acid excretion in short-bowel patients managed with an oral diet.

  Clinical nutrition (Edinburgh, Scotland) 20030201

• Functional characterization of Glu298Asp mutant human endothelial nitric oxide synthase purified from a yeast expression system.

  Nitric oxide : biology and chemistry 20030201

• Citrulline immunohistochemistry may not necessarily identify nitric oxide synthase activity: the pitfall of peptidylarginine deiminase.

  Nitric oxide : biology and chemistry 20030201

• HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells.

  Arteriosclerosis, thrombosis, and vascular biology 20030201

• [Early diagnosis of rheumatoid arthritis with a test based upon a specific antigen: cyclic citrullinated peptide].

  Nederlands tijdschrift voor geneeskunde 20030201

• Inhibition of arginine synthesis by urea: a mechanism for arginine deficiency in renal failure which leads to increased hydroxyl radical generation.

  Molecular and cellular biochemistry 20030201

• Arginine deprivation and tumour cell death: arginase and its inhibition.

  Molecular and cellular biochemistry 20030201

• Rapid stimulation of L-arginine transport by D-glucose involves p42/44(mapk) and nitric oxide in human umbilical vein endothelium.

  Circulation research 20030110

• Microperoxidase 8 catalysed nitrogen oxides formation from oxidation of N-hydroxyguanidines by hydrogen peroxide.

  European journal of biochemistry 20030101

• Isotopic investigation of nitric oxide metabolism in disease.

  Current opinion in clinical nutrition and metabolic care 20030101

• Late-onset presentation of ornithine transcarbamylase deficiency in a young woman with hyperammonemic coma.

  Annals of emergency medicine 20030101

• Expression pattern of a nuclear encoded mitochondrial arginine-ornithine translocator gene from Arabidopsis.

  BMC plant biology 20030101

• Effect of cardiopulmonary bypass on urea cycle intermediates and nitric oxide levels after congenital heart surgery.

  The Journal of pediatrics 20030101

• Moderate citrullinaemia without hyperammonaemia in a child with mutated and deficient argininosuccinate synthetase.

  Annals of clinical biochemistry 20030101

• Induction of citrulline-nitric oxide (NO) cycle enzymes and NO production in immunostimulated rat RPE-J cells.

  Experimental eye research 20030101

• The urea cycle in the liver of arthritic rats.

  Molecular and cellular biochemistry 20030101

• Is type 2 diabetes mellitus a vascular disease (atheroscleropathy) with hyperglycemia a late manifestation? The role of NOS, NO, and redox stress.

  Cardiovascular diabetology 20030101

• Important differences in nitric oxide synthase activity and predominant isoform in reproductive tissues from human and rat.

  Reproductive biology and endocrinology : RB&E 20030101

• Cyclic GMP mediates influence of macula densa nitric oxide over tubuloglomerular feedback.

  Kidney & blood pressure research 20030101

• [Role of nitric oxide and other endothelium-derived factors].

  Medicina (Kaunas, Lithuania) 20030101

• Supplemental L-arginine enhances wound healing in diabetic rats.

  Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20030101

• Roles of nitric oxide and superoxide in inflammation.

  Methods in molecular biology (Clifton, N.J.) 20030101

• Ornithine transcarbamylase deficiency: a urea cycle defect.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20030101

• [Anticitrulline antibodies - new marker in rheumatoid arthritis diagnostics].

  Medicina (Kaunas, Lithuania) 20030101

• Regional variations and age-related changes in nitric oxide synthase and arginase in the sub-regions of the hippocampus.

  Neuroscience 20030101

• Evaluation of a mass screening program for lysinuric protein intolerance in the northern part of Japan.

  Genetic testing 20030101

• Species, strain and developmental variations in hippocampal neuronal and endothelial nitric oxide synthase clarify discrepancies in nitric oxide-dependent synaptic plasticity.

  Neuroscience 20030101

• A transcription map of the 6p22.3 reading disability locus identifying candidate genes.

  BMC genomics 20030101

• Allopurinol challenge tests performed before and after living-related donor liver transplantation in citrullinaemia.

  Journal of inherited metabolic disease 20030101

• Nitric oxide synthase activity in human trophoblast, term placenta and pregnant myometrium.

  Reproductive biology and endocrinology : RB&E 20030101

• Cauda equina syndrome and nitric oxide synthase immunoreactivity in the spinal cord of the dog.

  Physiological research 20030101

• Changes in NOS protein expression and activity in the rat hippocampus, entorhinal and postrhinal cortices after unilateral electrolytic perirhinal cortex lesions.

  Hippocampus 20030101

• Regression of hepatocellular cancer in a patient treated with arginine deiminase.

  Hepato-gastroenterology 20030101

• Interaction between nitric oxide and cyclooxygenase pathways in endothelial cells.

  Journal of vascular research 20030101

• [Cyclic citrullinated peptide antibodies (anti-CCP) together with some other parameters used for serologic diagnosis of rheumatoid arthritis].

  Mikrobiyoloji bulteni 20030101

• High diagnostic performance of ELISA detection of antibodies to citrullinated antigens in rheumatoid arthritis.

  Scandinavian journal of rheumatology 20030101

• Differential gene expression in the kidney of sickle cell transgenic mice: upregulated genes.

  Blood cells, molecules & diseases 20030101

• Nitric oxide synthase expression and enzymatic activity in human brain tumors.

  Clinical neuropathology 20030101

• [Effect of the composition of branched chain amino acids, taurine, and tryptophan on the amino acid metabolism in experimental models of alcoholism].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101

• The role of nitric oxide in locomotor regulation in mice and its interaction with nitrous oxide.

  Proceedings of the Western Pharmacology Society 20030101

• Peptidylarginine deiminase, the arginine to citrulline converting enzyme, is frequently recognized by sera of patients with rheumatoid arthritis, systemic lupus erythematosus and primary Sjögren syndrome.

  Scandinavian journal of rheumatology 20030101

• Roles of B cells in rheumatoid arthritis.

  Arthritis research & therapy 20030101

• Serologic markers of early rheumatoid arthritis.

  Folia medica 20030101

• Liver and gastrointestinal transplantation at the University of Miami.

  Clinical transplants 20030101

• Plasma nitric oxide (nitrate/nitrite) levels in acute stroke and their relationship with severity and outcome.

  Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20030101

• Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes.

  The Journal of biological chemistry 20021220

• Involvement of nitric oxide in kainic acid-induced excitotoxicity in rat brain.

  Brain research 20021213

• Reduced myocardial and systemic L-arginine uptake in heart failure.

  Circulation research 20021213

• Expression of nitric oxide synthase and nitric oxide-sensitive guanylate cyclase in the crustacean cardiac ganglion.

  The Journal of comparative neurology 20021209

• Serum amino acid responses to three different exercise sessions in male power athletes.

  The Journal of sports medicine and physical fitness 20021201

• Involvement of nitric oxide in myotoxicity produced by diisopropylphosphorofluoridate (DFP)-induced muscle hyperactivity.

  Archives of toxicology 20021201

• Overexpression, purification, crystallization and preliminary X-ray crystallographic analysis of Pseudomonas aeruginosa L-arginine deiminase.

  Acta crystallographica. Section D, Biological crystallography 20021201

• Nitric oxide synthase activity in human pituitary adenomas.

  Acta neurologica Scandinavica 20021201

• Multiple functions of mfa-1, a putative pheromone precursor gene of Neurospora crassa.

  Eukaryotic cell 20021201

• Role of endothelin type B receptor in NO/cGMP signaling pathway in rat median eminence.

  Cellular and molecular neurobiology 20021201

• Pathogenesis and pathophysiology of citrin (a mitochondrial aspartate glutamate carrier) deficiency.

  Metabolic brain disease 20021201

• L-citrulline recycling by argininosuccinate synthetase and lyase in rat gastric fundus.

  European journal of pharmacology 20021129

• Cerebrospinal fluid and plasma concentrations of nitric oxide metabolites are increased in dementia with Lewy bodies.

  Neuroscience letters 20021122

• Maturation of [NiFe]-hydrogenases in Escherichia coli: the HypC cycle.

  Journal of molecular biology 20021122

• Cyclic stretch induces vascular smooth muscle cell alignment via NO signaling.

  American journal of physiology. Heart and circulatory physiology 20021101

• Human peptidylarginine deiminase type II: molecular cloning, gene organization, and expression in human skin.

  Archives of biochemistry and biophysics 20021101

• The antithyroid agent 6-n-propyl-2-thiouracil is a mechanism-based inactivator of the neuronal nitric oxide synthase isoform.

  Archives of biochemistry and biophysics 20021101

• Interorgan ammonia and amino acid metabolism in metabolically stable patients with cirrhosis and a TIPSS.

  Hepatology (Baltimore, Md.) 20021101

• Response of recombinant calcineurin to metal ions, reduction-oxidation agents, and enzymatic modification.

  Protein expression and purification 20021101

• Infantile citrullinemia caused by citrin deficiency with increased dibasic amino acids.

  Molecular genetics and metabolism 20021101

• Ultrasound improves tissue perfusion in ischemic tissue through a nitric oxide dependent mechanism.

  Thrombosis and haemostasis 20021101

• Insulin influences the nitric oxide cyclic nucleotide pathway in cultured human smooth muscle cells from corpus cavernosum by rapidly activating a constitutive nitric oxide synthase.

  European journal of endocrinology 20021101

• Anti-cyclic citrullinated peptide antibodies as a diagnostic test for rheumatoid arthritis and predictor of an erosive disease.

  The Israel Medical Association journal : IMAJ 20021101

• The metabolic basis of arginine nutrition and pharmacotherapy.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20021101

• The role of tetrahydrobiopterin in the regulation of neuronal nitric-oxide synthase-generated superoxide.

  The Journal of biological chemistry 20021025

• Comparative survey in Lactobacillus plantarum of the growth and metabolism of arginine and citrulline in different media.

  Journal of agricultural and food chemistry 20021023

• Role of platelet endothelial form of nitric oxide synthase in collagen-platelet interaction: regulation by phosphorylation.

  Biochimica et biophysica acta 20021021

• Glycoxidized low-density lipoprotein downregulates endothelial nitricoxide synthase in human coronary cells.

  Journal of the American College of Cardiology 20021016

• Inducible nitric oxide synthase is expressed in synovial fluid granulocytes.

  Clinical and experimental immunology 20021001

• Oral arginine reduces systemic blood pressure in type 2 diabetes: its potential role in nitric oxide generation.

  Journal of the American College of Nutrition 20021001

• Can the nitrogenous composition of xylem sap be used to assess salinity stress in Casuarina glauca?

  Tree physiology 20021001

• Pegylated arginine deiminase (ADI-SS PEG20,000 mw) inhibits human melanomas and hepatocellular carcinomas in vitro and in vivo.

  Cancer research 20021001

• Free radicals, antioxidants, and nutrition.

  Nutrition (Burbank, Los Angeles County, Calif.) 20021001

• L-Arginine supplementation enhances diabetic wound healing: involvement of the nitric oxide synthase and arginase pathways.

  Metabolism: clinical and experimental 20021001

• Rheumatoid factor and antibodies to cyclic citrullinated Peptide differentiate rheumatoid arthritis from undifferentiated polyarthritis in patients with early arthritis.

  The Journal of rheumatology 20021001

• Coupling sap flow velocity and amino acid concentrations as an alternative method to (15)N labeling for quantifying nitrogen remobilization by walnut trees.

  Plant physiology 20021001

• Is expression of intracellular citrullinated proteins in synovial tissue specific for rheumatoid arthritis? Comment on the article by Baeten et al.

  Arthritis and rheumatism 20021001

• Neuronal oxidative damage from activated innate immunity is EP2 receptor-dependent.

  Journal of neurochemistry 20021001

• Application of mutation analysis for the previously uncertain cases of adult-onset type II citrullinemia (CTLN2) and their clinical profiles.

  The Tohoku journal of experimental medicine 20021001

• 17Beta-estradiol rapid stimulation of rat aorta NOS activity is prevented by oestrogen deficiency.

  Maturitas 20020930

• Recombinant arginine deiminase as a potential anti-angiogenic agent.

  Cancer letters 20020926

• Red wine polyphenols enhance endothelial nitric oxide synthase expression and subsequent nitric oxide release from endothelial cells.

  Circulation 20020924

• Effect of nitric oxide on release of glutamate in the subretrofacial nucleus (SRF) during the exercise pressor reflex in cats.

  Brain research 20020920

• Dimethylarginine dimethylaminohydrolase I enhances tumour growth and angiogenesis.

  British journal of cancer 20020909

• Stimulation of tetrahydrobiopterin synthesis by cyclosporin A in mouse brain microvascular endothelial cells.

  The international journal of biochemistry & cell biology 20020901

• Novel substrates for nitric oxide synthases.

  Bioorganic & medicinal chemistry 20020901

• Transdermal oestradiol replacement therapy enhances platelet constitutive nitric oxide synthase activity in postmenopausal women with type 2 diabetes mellitus.

  Clinical endocrinology 20020901

• Alzheimer's disease is not associated with altered concentrations of the nitric oxide synthase inhibitor asymmetric dimethylarginine in cerebrospinal fluid.

  Journal of neural transmission (Vienna, Austria : 1996) 20020901

• Differential expression and localization of nitric oxide synthases in cirrhotic livers of bile duct-ligated rats.

  Nitric oxide : biology and chemistry 20020901

• NO synthesis and its regulation in the arachidonic-acid-stimulated rat polymorphonuclear leukocytes.

  Nitric oxide : biology and chemistry 20020901

• Plasma amino acid levels with a note on membrane transport: characteristics, regulation, and metabolic significance.

  Nutrition (Burbank, Los Angeles County, Calif.) 20020901

• Effects of intrauterine growth restriction and intraamniotic insulin-like growth factor-I treatment on blood and amniotic fluid concentrations and on fetal gut uptake of amino acids in late-gestation ovine fetuses.

  Journal of pediatric gastroenterology and nutrition 20020901

• Clinical, enzymatic, and molecular genetic characterization of a biochemical variant type of argininosuccinic aciduria: prenatal and postnatal diagnosis in five unrelated families.

  Journal of inherited metabolic disease 20020901

• Anti-cyclic citrullinated peptide antibodies in patients with juvenile idiopathic arthritis.

  Autoimmunity 20020901

• Inhibition of superoxide generation from neuronal nitric oxide synthase by heat shock protein 90: implications in NOS regulation.

  Biochemistry 20020827

• Superoxide activates constitutive nitric oxide synthase in a brain particulate fraction.

  Biochemical and biophysical research communications 20020816

• Glucose stimulates O2 consumption, NOS, and Na/H exchange in diabetic rat proximal tubules.

  American journal of physiology. Renal physiology 20020801

• Neuronal nitric oxide synthase modulates basal catecholamine secretion in bovine chromaffin cells.

  Journal of neuroscience research 20020801

• The activation of neuronal nitric-oxide synthase by various divalent cations.

  The Journal of pharmacology and experimental therapeutics 20020801

• Reduced arginine availability and nitric oxide production.

  Clinical nutrition (Edinburgh, Scotland) 20020801

• Citrulline/malate promotes aerobic energy production in human exercising muscle.

  British journal of sports medicine 20020801

• Effect of supplemental ornithine on wound healing.

  The Journal of surgical research 20020801

• L-arginine reduces exercise-induced increase in plasma lactate and ammonia.

  International journal of sports medicine 20020801

• Urea cycle disorders in Thai infants: a report of 5 cases.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20020801

• Intrauterine growth retardation is associated with reduced activity and expression of the cationic amino acid transport systems y+/hCAT-1 and y+/hCAT-2B and lower activity of nitric oxide synthase in human umbilical vein endothelial cells.

  Circulation research 20020726

• Automated capillary liquid chromatography for simultaneous determination of neuroactive amines and amino acids.

  Journal of chromatography. A 20020712

• Alkalosis stimulates endothelial nitric oxide synthase in cultured human pulmonary arterial endothelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20020701

• Deletion of exon 6 of the neuronal nitric oxide synthase gene in mice results in hypogonadism and infertility.

  Endocrinology 20020701

• Prevalence and clinical significance of anti-cyclic citrullinated peptide antibodies in juvenile idiopathic arthritis.

  Annals of the rheumatic diseases 20020701

• The flux of arginine after ischemia-reperfusion in the rat kidney.

  Kidney international 20020701

• Nitric oxide synthase activity in hyperthyroid and hypothyroid rats.

  European journal of endocrinology 20020701

• Diagnostic tests for rheumatoid arthritis: comparison of anti-cyclic citrullinated peptide antibodies, anti-keratin antibodies and IgM rheumatoid factors.

  Rheumatology (Oxford, England) 20020701

• Sex differences in amino acid release from rostral trigeminal subnucleus caudalis after acute injury to the TMJ region.

  Pain 20020701

• Prolonged mild fetal hypoxia up-regulates type I nitric oxide synthase expression in discrete areas of the late-gestation fetal sheep brain.

  American journal of obstetrics and gynecology 20020701

• Immune features of seronegative and seropositive arthritis in early synovitis studies.

  Current opinion in rheumatology 20020701

• Dinitrobenzene-mediated production of peroxynitrite by neuronal nitric oxide synthase.

  Chemical research in toxicology 20020701

• An Arg/Lys-->Gln mutant of recombinant murine myelin basic protein as a mimic of the deiminated form implicated in multiple sclerosis.

  Protein expression and purification 20020701

• Effects of the osmolyte trimethylamine-N-oxide on conformation, self-association, and two-dimensional crystallization of myelin basic protein.

  Journal of structural biology 20020701

• Increased and type II-specific expression of peptidylarginine deiminase in activated microglia but not hyperplastic astrocytes following kainic acid-evoked neurodegeneration in the rat brain.

  Neuroscience letters 20020628

• Hormonal induction of hepatic mitochondrial ornithine/citrulline transporter mRNA.

  Biochemical and biophysical research communications 20020621

• The influence of nitric oxide on basal and cholecystokinin-8-induced proliferation and apoptosis in the rat pancreas.

  Regulatory peptides 20020615

• Citrulline and DRIP-1 protein (ArgE homologue) in drought tolerance of wild watermelon.

  Annals of botany 20020615

• Novel lipoic acid analogues that inhibit nitric oxide synthase.

  Bioorganic & medicinal chemistry letters 20020603

• Microtubule-active agents modify nitric oxide production in pulmonary artery endothelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20020601

• Nitric oxide synthase, arginase and cyclooxygenase are involved in muscarinic receptor activation in different murine mammary adenocarcinoma cell lines.

  International journal of molecular medicine 20020601

• Inhibition of mesangial iNOS by reduced extracellular pH is associated with uncoupling of NADPH oxidation.

  Kidney international 20020601

• Hepatic glutaminase--a special role in urea synthesis?

  Nutrition (Burbank, Los Angeles County, Calif.) 20020601

• A case of acrodermatitis enteropathica-like dermatosis caused by ornithine transcarbamylase deficiency.

  Journal of the American Academy of Dermatology 20020601

• Evidence for the involvement of L-citrulline but not nitric oxide in the proconvulsant action of the precursor L-arginine on picrotoxin-induced convulsions in rats.

  Biochemical pharmacology 20020601

• Effects of Melilotus officinalis on acute inflammation.

  Phytotherapy research : PTR 20020601

• Improving the prenatal diagnosis of citrullinemia using citrulline/ornithine+arginine ratio in amniotic fluid.

  Prenatal diagnosis 20020601

• Neuropathic pain is associated with alterations of nitric oxide synthase immunoreactivity and catalytic activity in dorsal root ganglia and spinal dorsal horn.

  Brain research bulletin 20020601

• The regional distribution of nitric oxide synthase activity in the spinal cord of the dog.

  Brain research bulletin 20020601

• Crystal structure of argininosuccinate synthetase from Thermus thermophilus HB8. Structural basis for the catalytic action.

  The Journal of biological chemistry 20020503

• Activation of constitutive nitric-oxide synthase activity is an early signaling event induced by ionizing radiation.

  The Journal of biological chemistry 20020503

• Nongenomic action of progesterone in rat aorta: role of nitric oxide and prostaglandins.

  Cellular signalling 20020501

• Autoantigenic posttranslational modifications of proteins: does it apply to rheumatoid arthritis?

  Current opinion in rheumatology 20020501

• Nitric oxide and neuromodulation in the caudal neurosecretory system of teleosts.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020501

• Serum citrulline as a marker of acute cellular rejection for intestinal transplantation.

  Transplantation proceedings 20020501

• Serum citrulline is a potential marker for rejection of intestinal allografts.

  Transplantation proceedings 20020501

• The significance of nitric oxide production in the brain after injury.

  Annals of the New York Academy of Sciences 20020501

• L-Citrulline recycle for synthesis of NO in cerebral perivascular nerves and endothelial cells.

  Annals of the New York Academy of Sciences 20020501

• Identification of citrullinated rheumatoid arthritis-specific epitopes in natural filaggrin relevant for antifilaggrin autoantibody detection by line immunoassay.

  Arthritis and rheumatism 20020501

• The 'intestinal-renal' arginine biosynthetic axis in the aging rat.

  Mechanisms of ageing and development 20020430

• Presence and activity of nitric oxide synthase isoforms in ischemia-reperfusion-injured flaps.

  Plastic and reconstructive surgery 20020415

• Substrate induced conformational changes in argininosuccinate synthetase.

  The Journal of biological chemistry 20020412

• A conserved tryptophan 457 modulates the kinetics and extent of N-hydroxy-L-arginine oxidation by inducible nitric-oxide synthase.

  The Journal of biological chemistry 20020412

• Expression of nitric oxide synthases in rat adrenal zona fasciculata cells.

  Endocrinology 20020401

• Does nitric oxide act as a cellular messenger in muscarinic endometrial secretion in the guinea-pig?

  Acta physiologica Scandinavica 20020401

• [Mitochondrial urea cycle and related enzymes].

  Nihon rinsho. Japanese journal of clinical medicine 20020401

• [Structure-function relationships of mitochondrial transporters].

  Nihon rinsho. Japanese journal of clinical medicine 20020401

• [Mitochondrial ornithine transporter deficiency].

  Nihon rinsho. Japanese journal of clinical medicine 20020401

• High levels of nitric oxide synthase activity are associated with nasal polyp tissue from aspirin-sensitive asthmatics.

  Acta oto-laryngologica 20020401

• Plasma free amino acids in Taiwan Chinese: the effect of age.

  Clinical chemistry and laboratory medicine 20020401

• Peptidylarginine deiminase: a candidate factor in demyelinating disease.

  Journal of neurochemistry 20020401

• Expression of type 2 nitric oxide synthase and p21 in oral squamous cell carcinoma.

  International journal of oral and maxillofacial surgery 20020401

• [Nitric oxide synthases and peripheral cardiovascular system].

  Annales de cardiologie et d'angeiologie 20020401

• Decreased nitric oxide synthesis in human endothelial cells cultured on type I collagen.

  Circulation research 20020322

• Preparation of a monoclonal antibody to citrullinated epitopes: its characterization and some applications to immunohistochemistry in human brain.

  Glia 20020315

• A brain nitric oxide synthase study in the rat: production of a nitroso-compound NA and absence of nitric oxide synthesis.

  Neuroscience letters 20020315

• Evidence for a functional nitric oxide synthase system in brown adipocyte nucleus.

  FEBS letters 20020313

• Reactions catalyzed by the heme domain of inducible nitric oxide synthase: evidence for the involvement of tetrahydrobiopterin in electron transfer.

  Biochemistry 20020312

• Arginase in glomerulonephritis.

  Kidney international 20020301

• Apraclonidine attenuates the increases in spinal excitatory amino acid release in rats with adjuvant-induced inflammation.

  Anesthesia and analgesia 20020301

• Nitric-oxide-mediated relaxations in salt-induced hypertension: effect of chronic beta1 -selective receptor blockade.

  Journal of hypertension 20020301

• Identification of a by-product of nitric oxide synthase activity in human acute brain injury with in vivo proton magnetic resonance spectroscopy.

  AJNR. American journal of neuroradiology 20020301

• Complementary distribution of NADPH-diaphorase and l-arginine in the snail nervous system.

  Cell and tissue research 20020301

• Absence of anti-cyclic citrullinated peptide antibodies in antineutrophil cytoplasmic antibody-associated vasculitis.

  Arthritis and rheumatism 20020301

• Insulin increases NADH/NAD+ redox state, which stimulates guanylate cyclase in vascular smooth muscle.

  American journal of hypertension 20020301

• The antiproliferative and immunotoxic effects of L-canavanine and L-canaline.

  Anti-cancer drugs 20020301

• Characterization of mycoplasma arginine deiminase expressed in E. coli and its inhibitory regulation of nitric oxide synthesis.

  Molecules and cells 20020227

• Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway.

  The Journal of biological chemistry 20020222

• Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity.

  Blood 20020215

• Renal arginine and protein synthesis are increased during early endotoxemia in mice.

  American journal of physiology. Renal physiology 20020201

• Microglial derived nitric oxide decreases serotonin content in rat basophilic leukemia (RBL-2H3) cells.

  European journal of pharmacology 20020201

• Recognition and invasion of human skin by Schistosoma mansoni cercariae: the key-role of L-arginine.

  Parasitology 20020201

• Arginine catabolism in lactating porcine mammary tissue.

  Journal of animal science 20020201

• N-Acetylcysteine negatively modulates nitric oxide production in endotoxin-treated rats through inhibition of NF-kappaB activation.

  Antioxidants & redox signaling 20020201

• Deimination of arginine residues in nucleophosmin/B23 and histones in HL-60 granulocytes.

  Biochemical and biophysical research communications 20020125

• Effects of the incorporation of IBTM beta-turn mimetics into the dipeptoid CCK(1) receptor agonist PD 170292.

  Bioorganic & medicinal chemistry letters 20020121

• Coordinate regulation of L-arginine uptake and nitric oxide synthase activity in cultured endothelial cells.

  Free radical biology & medicine 20020115

• Perferryl complex of nitric oxide synthase: role in secondary free radical formation.

  Biochimica et biophysica acta 20020115

• Cardiac-specific overexpression of inducible nitric oxide synthase does not result in severe cardiac dysfunction.

  Circulation research 20020111

• Changes in NOS activity and protein expression during acute and prolonged ANG II administration.

  American journal of physiology. Regulatory, integrative and comparative physiology 20020101

• Citrulline is not the major product using the standard 'NOS activity' assay on renal cortical homogenates.

  American journal of physiology. Regulatory, integrative and comparative physiology 20020101

• A patient with adult-onset type II citrullinemia on long-term hemodialysis: reversal of clinical symptoms and brain MRI findings.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20020101

• L-arginine-nitric oxide pathway in end-stage renal disease.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20020101

• Effect of homocysteine on the L-arginine/nitric oxide synthase/nitric oxide pathway in human platelets.

  Heart and vessels 20020101

• Citrulline as the main precursor of ethyl carbamate in model fortified wines inoculated with Lactobacillus hilgardii: a marker of the levels in a spoiled fortified wine.

  Letters in applied microbiology 20020101

• [Biological and pathophysiological roles of endogenous methylarginines as inhibitors of nitric oxide synthase].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20020101

• [The arginine paradox].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20020101

• Autoantibody systems in rheumatoid arthritis: specificity, sensitivity and diagnostic value.

  Arthritis research 20020101

• Auto-protective redox buffering systems in stimulated macrophages.

  BMC immunology 20020101

• Stimulation of arginine consumption and asparagine production in LPS-activated macrophages.

  Anticancer research 20020101

• Effects of arginine, L-alanyl-L-glutamine or taurine on neutrophil (PMN) free amino acid profiles and immune functions in vitro.

  Amino acids 20020101

• CHF2819: pharmacological profile of a novel acetylcholinesterase inhibitor.

  CNS drug reviews 20020101

• Why do we not have a cure for rheumatoid arthritis?

  Arthritis research 20020101

• Autoantibodies in rheumatoid arthritis and their clinical significance.

  Arthritis research 20020101

• Renal focal tubulointerstitial fibrosis with short bowel syndrome: report of a case.

  Surgery today 20020101

• Antitubercular therapy decreases nitric oxide production in HIV/TB coinfected patients.

  BMC infectious diseases 20020101

• Investigation of extracellular amino acid release in children with severe head injury using microdialysis. A pilot study.

  Acta neurochirurgica. Supplement 20020101

• Diverse biological activities of fermented pine seed shell extract.

  Anticancer research 20020101

• Effects of isoflavones from Sophora species on the growth and activation of a mouse macrophage-like cell line.

  Anticancer research 20020101

• L-citrulline immunostaining identifies nitric oxide production sites within neurons.

  Neuroscience 20020101

• Diagnosing early-onset rheumatoid arthritis: the role of anti-CCP antibodies.

  American clinical laboratory 20020101

• Intimal redox stress: accelerated atherosclerosis in metabolic syndrome and type 2 diabetes mellitus. Atheroscleropathy.

  Cardiovascular diabetology 20020101

• Lack of a role of neuronal nitric oxide synthase in the regulation of the renal function in rats fed a low-sodium diet.

  Kidney & blood pressure research 20020101

• Haemorheological and endothelial-dependent alterations in heart failure after ACE inhibitor, calcium antagonist and beta blocker.

  Clinical hemorheology and microcirculation 20020101

• Synthesis and characterization of nitric oxide generative polyrotaxane.

  Journal of biomaterials science. Polymer edition 20020101

• Clinical review: Myocardial depression in sepsis and septic shock.

  Critical care (London, England) 20020101

• Neonatal presentation of ventricular tachycardia and a Reye-like syndrome episode associated with disturbed mitochondrial energy metabolism.

  BMC pediatrics 20020101

• Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats.

  Physiological research 20020101

• Effect of lignins and their precursors on nitric oxide, citrulline and asparagine production by mouse macrophage-like Raw 264.7 cells.

  Anticancer research 20020101

• Effect of poly-herbal formula on NO production by LPS-stimulated mouse macrophage-like cells.

  Anticancer research 20020101

• Citrullinemia type II in a 64-year-old man with fluctuating serum citrulline levels: mutations in the SLC25A13 gene.

  Journal of the neurological sciences 20011215

• Mitochondrial nitric oxide synthase is constitutively active and is functionally upregulated in hypoxia.

  Free radical biology & medicine 20011215

• Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome.

  American journal of respiratory and critical care medicine 20011215

• Calculated background elimination in quantifying nitric-oxide synthase enzyme activity.

  Journal of biochemical and biophysical methods 20011204

• In situ measurement of nitric oxide production in cardiac isografts and rejecting allografts by an electrochemical method.

  Nitric oxide : biology and chemistry 20011201

• The 1.6 A crystal structure of E. coli argininosuccinate synthetase suggests a conformational change during catalysis.

  Structure (London, England : 1993) 20011201

• Secondhand tobacco smoke impairs rabbit pulmonary artery endothelium-dependent relaxation.

  Chest 20011201

• University of Wisconsin solution increases hyperpolarizing mechanisms in response to bradykinin.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20011201

• Free amino acid concentration in hydatid cyst fluids from fertile and infertile human and animal Echinococcus granulosus.

  Parasite (Paris, France) 20011201

• An enzyme hydrolyzing methylated inhibitors of nitric oxide synthase is present in circulating human red blood cells.

  Free radical research 20011201

• Investigation of extracellular L-citrulline concentration in the striatum during alcohol withdrawal in rats.

  Neurochemical research 20011201

• Structural requirements of benzodiazepines for the inhibition of pig brain nitric oxide synthase.

  Brain research. Molecular brain research 20011130

• Citrulline, a novel compatible solute in drought-tolerant wild watermelon leaves, is an efficient hydroxyl radical scavenger.

  FEBS letters 20011123

• 3-Ureidopropionate contributes to the neuropathology of 3-ureidopropionase deficiency and severe propionic aciduria: a hypothesis.

  Journal of neuroscience research 20011115

• L-citrulline mediated relaxation in the control and lipopolysaccharide-treated rat aortic rings.

  European journal of pharmacology 20011109

• Type II (adult onset) citrullinaemia: clinical pictures and the therapeutic effect of liver transplantation.

  Journal of neurology, neurosurgery, and psychiatry 20011101

• Comparison of neuronal and endothelial isoforms of nitric oxide synthase in stably transfected HEK 293 cells.

  American journal of physiology. Heart and circulatory physiology 20011101

• Seven novel mutations in the ORNT1 gene (SLC25A15) in patients with hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome.

  Human mutation 20011101

• Free amino acids in walnut kernels and young seedlings.

  Tree physiology 20011101

• Ginsenosides Rb1 and Re decrease cardiac contraction in adult rat ventricular myocytes: role of nitric oxide.

  British journal of pharmacology 20011101

• 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors upregulate inducible NO synthase expression and activity in vascular smooth muscle cells.

  Hypertension (Dallas, Tex. : 1979) 20011101

• [Molecular genetic studies of mitochondrial ornithine transporter deficiency (HHH syndrome)].

  Nihon rinsho. Japanese journal of clinical medicine 20011101

• L-arginine infusion lowers blood pressure in children.

  The Journal of pediatrics 20011101

• Aortic smooth muscle cell proliferation and endothelial nitric oxide synthase activity in fructose-fed rats.

  American journal of hypertension 20011101

• Amino acid residues important for substrate specificity of the amino acid permeases Can1p and Gnp1p in Saccharomyces cerevisiae.

  Yeast (Chichester, England) 20011101

• NO message from muscle.

  Microscopy research and technique 20011101

• Serum citrulline and rejection in small bowel transplantation: a preliminary report.

  Transplantation 20011015

• Regulation of the properties of the heme-NO complexes in nitric-oxide synthase by hydrogen bonding to the proximal cysteine.

  The Journal of biological chemistry 20011012

• The role of nitric oxide in the reversal of hemorrhagic shock by oxotremorine.

  European journal of pharmacology 20011005

• Mechanisms of ammonia and amino acid photoproduction from aquatic humic and colloidal matter.

  Water research 20011001

• Cardiac surgery increases the activity of matrix metalloproteinases and nitric oxide synthase in human hearts.

  The Journal of thoracic and cardiovascular surgery 20011001

• Augmented age-associated innate immune responses contribute to negative inotropic and lusitropic effects of lipopolysaccharide and interferon gamma.

  Journal of molecular and cellular cardiology 20011001

• Effects of the reactive oxygen species hydrogen peroxide and hypochlorite on endothelial nitric oxide production.

  Hypertension (Dallas, Tex. : 1979) 20011001

• Specific presence of intracellular citrullinated proteins in rheumatoid arthritis synovium: relevance to antifilaggrin autoantibodies.

  Arthritis and rheumatism 20011001

• Oral citrulline as arginine precursor may be beneficial in sickle cell disease: early phase two results.

  Journal of the National Medical Association 20011001

• Monoclonal L-citrulline immunostaining reveals nitric oxide-producing vestibular neurons.

  Annals of the New York Academy of Sciences 20011001

• Ruthenium(III) readily abstracts NO from L-arginine, the physiological precursor to NO, in the presence of H2O2. A remarkably simple model system for NO synthases.

  Chemical communications (Cambridge, England) 20010921

• Clinical and molecular findings in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome.

  Neurology 20010911

• Sepsis is associated with reciprocal expressional modifications of constitutive nitric oxide synthase (NOS) in human skeletal muscle: down-regulation of NOS1 and up-regulation of NOS3.

  Critical care medicine 20010901

• Neuronal and glial coexpression of argininosuccinate synthetase and inducible nitric oxide synthase in Alzheimer disease.

  Journal of neuropathology and experimental neurology 20010901

• Expression of cytokines, inducible nitric oxide synthase, and matrix metalloproteinases in pouchitis: effects of probiotic treatment.

  The American journal of gastroenterology 20010901

• Role of pH on the calcium ion dependence of the nitric oxide synthase in the carp brain.

  Brain research bulletin 20010901

• Enalapril acts through release of nitric oxide in patients with essential hypertension.

  Renal failure 20010901

• Effects of ENA713 and CHF2819, two anti-Alzheimer's disease drugs, on rat amino acid levels.

  Brain research 20010810

• Inducible nitric oxide synthase in rat neutrophils: role of insulin.

  Biochemical pharmacology 20010801

• Nitric oxide synthesis and oxidative stress in the renal cortex of rats with diabetes mellitus.

  Journal of the American Society of Nephrology : JASN 20010801

• Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase.

  Nature structural biology 20010801

• X-ray absorption spectroscopic analysis of the high-spin ferriheme site in substrate-bound neuronal nitric-oxide synthase.

  Journal of biochemistry 20010801

• N-acetylcysteine inhibits in vivo nitric oxide production by inducible nitric oxide synthase.

  Nitric oxide : biology and chemistry 20010801

• Neuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicity.

  British journal of pharmacology 20010801

• Role of nNOS in regulation of renal function in angiotensin II-induced hypertension.

  Hypertension (Dallas, Tex. : 1979) 20010801

• Metabonomic investigations into hydrazine toxicity in the rat.

  Chemical research in toxicology 20010801

• Nitric oxide synthase activity in neutrophils from patients with localized aggressive periodontitis.

  Journal of periodontology 20010801

• Response of nitric oxide pathway to L-arginine infusion at the altitude of 4,350 m.

  The European respiratory journal 20010801

• Nitric oxide modulates high-energy phosphates in brain regions of rats intoxicated with diisopropylphosphorofluoridate or carbofuran: prevention by N-tert-butyl-alpha-phenylnitrone or vitamin E.

  Archives of toxicology 20010801

• Structural requirements for conserved arginine of parathyroid hormone.

  Biochemistry 20010731

• Role of PI3-kinase in isoproterenol and IGF-1 induced ecNOS activity.

  Biochemical and biophysical research communications 20010727

• Development of specific CXCR4 inhibitors possessing high selectivity indexes as well as complete stability in serum based on an anti-HIV peptide T140.

  Bioorganic & medicinal chemistry letters 20010723

• Progesterone and 17 beta-estradiol acutely stimulate nitric oxide synthase activity in rat aorta and inhibit platelet aggregation.

  Life sciences 20010706

• IgG reactivity against citrullinated myelin basic protein in multiple sclerosis.

  Journal of neuroimmunology 20010702

• Arginine metabolism and the synthesis of nitric oxide in the nervous system.

  Progress in neurobiology 20010701

• Phenanthraquinone inhibits eNOS activity and suppresses vasorelaxation.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010701

• Ornithine aminotransferase messenger RNA expression and enzymatic activity in fetal porcine intestine.

  Pediatric research 20010701

• Expression control and specificity of the basic amino acid exporter LysE of Corynebacterium glutamicum.

  Microbiology (Reading, England) 20010701

• A Chinese adult onset type II citrullinaemia patient with 851del4/1638ins23 mutations in the SLC25A13 gene.

  Journal of medical genetics 20010701

• Decreased pulmonary and tracheal smooth muscle expression and activity of type 1 nitric oxide synthase (nNOS) after ovalbumin immunization and multiple aerosol challenge in guinea pigs.

  American journal of respiratory and critical care medicine 20010701

• Neuroprotective effect of sigma(1)-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is linked to reduced neuronal nitric oxide production.

  Stroke 20010701

• Role of nitric oxide synthase in the light-induced development of sporangiophores in Phycomyces blakesleeanus.

  Plant physiology 20010701

• New data and concepts on glutamine and glucose metabolism in the gut.

  Current opinion in clinical nutrition and metabolic care 20010701

• Influence of 72% injury in one kidney on several organs involved in guanidino compound metabolism: a time course study.

  Pflugers Archiv : European journal of physiology 20010701

• Co-induction of argininosuccinate synthetase, cationic amino acid transporter-2, and nitric oxide synthase in activated murine microglial cells.

  Brain research. Molecular brain research 20010620

• Neonatal pulmonary hypertension--urea-cycle intermediates, nitric oxide production, and carbamoyl-phosphate synthetase function.

  The New England journal of medicine 20010614

• Radiochemical nitric oxide synthase activity determination in rat brain with fast and accurate HPLC analysis.

  Brain research. Brain research protocols 20010601

• Nitric oxide synthase in porcine heart mitochondria: evidence for low physiological activity.

  American journal of physiology. Heart and circulatory physiology 20010601

• Diagnostic accuracy of the anti-citrulline antibody assay for rheumatoid arthritis.

  Clinical chemistry 20010601

• Coinduction of endothelial nitric oxide synthase and arginine recycling enzymes in aorta of diabetic rats.

  Nitric oxide : biology and chemistry 20010601

• Involvement of cyclic guanosine 3',5'-monophosphate in nitric oxide-induced glucagon secretion from pancreatic alpha cells.

  Metabolism: clinical and experimental 20010601

• HHH syndrome associated with callosal agenesis and disordered neuronal migration.

  Developmental medicine and child neurology 20010601

• Methohexital affects neutrophil (PMN) dynamic free amino acid pool and immune functions in vitro.

  European journal of anaesthesiology 20010601

• Amino acid concentrations in fluids from the bovine oviduct and uterus and in KSOM-based culture media.

  Theriogenology 20010601

• Detection of neonatal argininosuccinate lyase deficiency by serum tandem mass spectrometry.

  Journal of inherited metabolic disease 20010601

• A pediatric patient with classical citrullinemia who underwent living-related partial liver transplantation.

  Transplantation 20010527

• Helicobacter pylori lipopolysaccharide-provoked injury to rat gastroduodenal microvasculature involves inducible nitric oxide synthase.

  European journal of pharmacology 20010525

• Increased expression of arginase II in human diabetic corpus cavernosum: in diabetic-associated erectile dysfunction.

  Biochemical and biophysical research communications 20010518

• Convenient method for the determination of arginine and its related compounds in rumen fluid by reversed-phase high-performance liquid chromatography.

  Journal of chromatography. B, Biomedical sciences and applications 20010505

• Peroxynitrite inhibits inducible (type 2) nitric oxide synthase in murine lung epithelial cells in vitro.

  Free radical biology & medicine 20010501

• Retinoic acid attenuates inducible nitric oxide synthase (NOS2) activation in cultured rat cardiac myocytes and microvascular endothelial cells.

  Journal of molecular and cellular cardiology 20010501

• Control of electron transfer in neuronal NO synthase.

  Biochemical Society transactions 20010501

• Cigarette smoke-induced endothelium dysfunction: role of superoxide anion.

  Journal of hypertension 20010501

• Extremely short small bowel induces focal tubulointerstitial fibrosis.

  Journal of pediatric gastroenterology and nutrition 20010501

• Increased nitric oxide production by neutrophils in bronchial asthma.

  The European respiratory journal 20010501

• Measurement of NO and NO synthase.

  Current protocols in neuroscience 20010501

• Nitric oxide synthase assays.

  Current protocols in pharmacology 20010501

• Hypochlorite-modified low density lipoprotein inhibits nitric oxide synthesis in endothelial cells via an intracellular dislocalization of endothelial nitric-oxide synthase.

  The Journal of biological chemistry 20010427

• The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide.

  The Journal of biological chemistry 20010427

• Ceramide reduces endothelium-dependent vasodilation by increasing superoxide production in small bovine coronary arteries.

  Circulation research 20010427

• Vaginocervical stimulation-induced release of classical neurotransmitters and nitric oxide in the nucleus of the solitary tract varies as a function of the oestrus cycle.

  Brain research 20010420

• Nitric oxide and nitric oxide synthase in Huntington's disease.

  Journal of neuroscience research 20010415

• Cholinergic-nitrergic transmitter mechanisms in the cerebral circulation.

  Microscopy research and technique 20010415

• Role of nitric oxide in renal tubular apoptosis of unilateral ureteral obstruction.

  Kidney international 20010401

• Effect of arginine on cyclosporine-induced systemic hypertension after cardiac transplantation in the young.

  The American journal of cardiology 20010401

• Ornithine transcarbamylase deficiency unmasked because of gastrointestinal bleeding.

  Journal of clinical gastroenterology 20010401

• Caveolar localization of arginine regeneration enzymes, argininosuccinate synthase, and lyase, with endothelial nitric oxide synthase.

  Nitric oxide : biology and chemistry 20010401

• Time course of inducible nitric oxide synthase activity following endotoxin administration in dogs.

  Nitric oxide : biology and chemistry 20010401

• Effects of dietary L-arginine on structure and function of flow-restricted vein grafts.

  Journal of vascular surgery 20010401

• Selective inhibition of human inducible nitric oxide synthase by S-alkyl-L-isothiocitrulline-containing dipeptides.

  British journal of pharmacology 20010401

• Endothelial nitric oxide synthase (eNOS) expression and localization in healthy and diabetic rat hearts.

  Annals of clinical and laboratory science 20010401

• Metabolic effects of intraportal nutrition in humans.

  Nutrition (Burbank, Los Angeles County, Calif.) 20010401

• Angiotensin-converting enzyme inhibitors and AT1-receptor antagonist restore nitric oxide synthase (NOS) activity and neuronal NOS expression in the adrenal glands of spontaneously hypertensive rats.

  Japanese journal of pharmacology 20010401

• Depletion of energy metabolites following acetylcholinesterase inhibitor-induced status epilepticus: protection by antioxidants.

  Neurotoxicology 20010401

• Effect of exercise on the metabolism of vitamin B6 and some PLP-dependent enzymes in young rats fed a restricted vitamin B6 diet.

  Journal of nutritional science and vitaminology 20010401

• Carbamoylation of glomerular and tubular proteins in patients with kidney failure: a potential mechanism of ongoing renal damage.

  Swiss medical weekly 20010324

• The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deiminated forms of the alpha- and beta-chains of fibrin.

  Journal of immunology (Baltimore, Md. : 1950) 20010315

• Indomethacin prevents the induction of inducible nitric oxide synthase in murine peritoneal macrophages and decreases their nitric oxide production.

  Life sciences 20010309

• Ace-inhibition with quinapril modulates the nitric oxide pathway in normotensive rats.

  Journal of molecular and cellular cardiology 20010301

• Neural network partitioning by NO and cGMP.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010301

• Arginase I expression and activity in human mononuclear cells after injury.

  Annals of surgery 20010301

• Nitric oxide synthases in pregnant rat uterus.

  Reproduction (Cambridge, England) 20010301

• In vivo confocal Raman microspectroscopy of the skin: noninvasive determination of molecular concentration profiles.

  The Journal of investigative dermatology 20010301

• Simultaneous detection of NOS-3 protein expression and nitric oxide production using a flow cytometer.

  Analytical biochemistry 20010301

• Regulation of NO synthase isoforms in the peritoneum: implications for ultrafiltration failure in peritoneal dialysis.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010301

• Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells.

  Journal of cardiovascular pharmacology 20010301

• Nitric oxide synthase isoforms during fracture healing.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010301

• Short-term oral administration of L-arginine improves hemodynamics and exercise capacity in patients with precapillary pulmonary hypertension.

  American journal of respiratory and critical care medicine 20010301

• Immunohistochemical localization of nitric oxide synthase and soluble guanylyl cyclase in the ventral cochlear nucleus of the rat.

  The Journal of comparative neurology 20010226

• Arginine catabolism by Thermanaerovibrio acidaminovorans.

  FEMS microbiology letters 20010220

• Protein deimination in the rat brain after kainate administration: citrulline-containing proteins as a novel marker of neurodegeneration.

  Neuroscience letters 20010216

• Antineutrophil cytoplasm antibody-induced neutrophil nitric oxide production is nitric oxide synthase independent.

  Kidney international 20010201

• Relationship of asymmetric dimethylarginine to dialysis treatment and atherosclerotic disease.

  Kidney international. Supplement 20010201

• Role of nitric oxide in the synthesis of guanidinosuccinic acid, an activator of the N-methyl-D-aspartate receptor.

  Kidney international. Supplement 20010201

• Bacillus Calmette-Guerin induces long-term local formation of nitric oxide in the bladder via the induction of nitric oxide synthase activity in urothelial cells.

  The Journal of urology 20010201

• Nitric oxide generation by hemocytes of the mussel Mytilus galloprovincialis.

  Nitric oxide : biology and chemistry 20010201

• Effects of oral L-arginine on plasma nitrate and blood pressure in cortisol-treated humans.

  Journal of hypertension 20010201

• Superoxide inhibits neuronal nitric oxide synthase influences on afferent arterioles in spontaneously hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20010201

• [The immunologic homunculus in rheumatoid arthritis. A new viewpoint of immunopathogenesis in rheumatoid arthritis and therapeutic consequences].

  Zeitschrift fur Rheumatologie 20010201

• Characterization of a putative nitric oxide synthase in the neuromuscular system of the parasitic nematode, Ascaris suum.

  Parasitology 20010201

• Formation of a protonated trihydrobiopterin radical cation in the first reaction cycle of neuronal and endothelial nitric oxide synthase detected by electron paramagnetic resonance spectroscopy.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20010201

• Neurotransmitter sampling and storage for capillary electrophoresis analysis.

  Fresenius' journal of analytical chemistry 20010201

• Serum and urine nitrite and citrulline levels among patients with systemic lupus erythematosus: a possible addition to activity parameters?

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20010201

• Kinetic mechanism of antiports catalyzed by reconstituted ornithine/citrulline carrier from rat liver mitochondria.

  Biochimica et biophysica acta 20010119

• Nitric oxide synthase activity in peripheral polymorphonuclear leukocytes in patients with chronic congestive heart failure.

  The American journal of cardiology 20010115

• A kinetic simulation model that describes catalysis and regulation in nitric-oxide synthase.

  The Journal of biological chemistry 20010112

• C60-Fullerene monomalonate adducts selectively inactivate neuronal nitric oxide synthase by uncoupling the formation of reactive oxygen intermediates from nitric oxide production.

  Biochemistry 20010109

• L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin.

  The Journal of biological chemistry 20010105

• Use of anti-citrullinated peptide and anti-RA33 antibodies in distinguishing erosive arthritis in patients with systemic lupus erythematosus and rheumatoid arthritis.

  Annals of the rheumatic diseases 20010101

• Cyclic GMP-dependent relaxation of isolated rat renal glomeruli induced by extracellular ATP.

  The Journal of physiology 20010101

• Citrullinemia type II in a 64-year-old man with fluctuating serum citrulline levels.

  Journal of the neurological sciences 20010101

• Expression, but not activity, of neuronal nitric oxide synthase is regionally increased in the alcoholic brain.

  Alcohol and alcoholism (Oxford, Oxfordshire) 20010101

• Ornithine transcarbamylase deficiency and pancreatitis.

  The Journal of pediatrics 20010101

• Laboratory evaluation of urea cycle disorders.

  The Journal of pediatrics 20010101

• Long-term management of patients with urea cycle disorders.

  The Journal of pediatrics 20010101

• Nerve injury induces a rapid efflux of nitric oxide (NO) detected with a novel NO microsensor.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010101

• Effect of isosorbide dinitrate on nitric oxide synthase under hypoxia.

  Pharmacology 20010101

• Nitric oxide and substance dependence.

  Neuroscience and biobehavioral reviews 20010101

• Metabolic flux measurements across portal drained viscera, liver, kidney and hindquarter in mice.

  Laboratory animals 20010101

• Secretion of anti-citrulline-containing peptide antibody by B lymphocytes in rheumatoid arthritis.

  Arthritis and rheumatism 20010101

• Temporal expression of nitric oxide synthase isoforms in healing Achilles tendon.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20010101

• Plant amino acid research in retrospect: from Chinball to Singh.

  Amino acids 20010101

• Is the balance between nitric oxide and superoxide altered in spontaneously hypertensive rats with endothelial dysfunction?

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101

• Gastrectomized patients are in a state of chronic protein malnutrition analyses of 23 amino acids.

  Hepato-gastroenterology 20010101

• Extracting biological information from DNA arrays: an unexpected link between arginine and methionine metabolism in Bacillus subtilis.

  Genome biology 20010101

• Endothelial cell dysfunction in a model of oxidative stress.

  Medical science monitor : international medical journal of experimental and clinical research 20010101

• Metabolic effects of arginine addition to the enteral feeding of critically ill patients.

  JPEN. Journal of parenteral and enteral nutrition 20010101

• [Citrullinemia].

  Ryoikibetsu shokogun shirizu 20010101

• [Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome].

  Ryoikibetsu shokogun shirizu 20010101

• Heat stress-activated, calcium-dependent nitric oxide synthase in sponges.

  Nitric oxide : biology and chemistry 20010101

• Endogenous bacteria-triggered inducible nitric oxide synthase activation protects the ovariectomized rat stomach.

  Journal of physiology, Paris 20010101

• Attenuation of Helicobacter pylori endotoxin-provoked rat intestinal inflammation by selective inhibition of the inducible nitric oxide synthase.

  Journal of physiology, Paris 20010101

• GABA, taurine and learning: release of amino acids from slices of chick brain following filial imprinting.

  Neuroscience 20010101

• The effect of repeated sublethal ischemia on NO/cGMP signal transduction system in gray matter of the rabbit spinal cord.

  Bratislavske lekarske listy 20010101

• Analysis of amino acids as formamidene butyl esters by electrospray ionization tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20010101

• Conscientious metabolic monitoring on a patient with hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome undergoing anaesthesia.

  Amino acids 20010101

• [Nitrullin -- a new original Russian drug of the nitrosomethylurea group].

  Voprosy onkologii 20010101

• Macrophage arginine metabolism to ornithine/urea or nitric oxide/citrulline: a life or death issue.

  Critical reviews in immunology 20010101

• Endotoxin augments cerebral hyperemic response to halothane by inducing nitric oxide synthase and cyclooxygenase.

  Anesthesia and analgesia 20001001

• nNOS inhibitors attenuate methamphetamine-induced dopaminergic neurotoxicity but not hyperthermia in mice.

  Neuroreport 20000911

• Nitric oxide regulates renal cortical cyclooxygenase-2 expression.

  American journal of physiology. Renal physiology 20000701

• Effect of oral magnesium supplementation on blood pressure, platelet aggregation and calcium handling in deoxycorticosterone acetate induced hypertension in rats.

  Journal of hypertension 20000701

• NADH oxidase activation is involved in arsenite-induced oxidative DNA damage in human vascular smooth muscle cells.

  Circulation research 20000317

• Interactions of the renin-angiotensin system and neuronal nitric oxide synthase in regulation of cyclooxygenase-2 in the macula densa.

  Acta physiologica Scandinavica 20000101

• L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat.

  Blood pressure 20000101

• Anticonvulsant activity of new and potent inhibitors of nitric oxide synthase.

  Brain research bulletin 19970101

• Identification of a mitogen-activated protein kinase site in human myelin basic protein in situ.

  Journal of neuroimmunology 19960301

• Systemic administration of lithium chloride and tacrine but not kainic acid augments citrulline content of rat brain.

  European journal of pharmacology 19951227

• Effects of valproate and citrulline on ammonium-induced encephalopathy.

  Epilepsia 19940101

• Reactivity of two anti-galactosyl ceramide antibodies towards myelin basic protein.

  Journal of the neurological sciences 19920301

• The preparation of antibodies reactive against citrulline-containing charge isomers of myelin basic protein but not against the arginine-containing charge isomers.

  Analytical biochemistry 19901201

• The specificity of two proteinases that cleave adjacent to arginine, C1 esterase and acrosin, for peptide p-nitroanilide substrates.

  Biochimica et biophysica acta 19890613

• Effect of sodium benzoate and sodium phenylacetate on brain serotonin turnover in the ornithine transcarbamylase-deficient sparse-fur mouse.

  Pediatric research 19880401

• [A patient with neonatal citrullinemia].

  Tijdschrift voor kindergeneeskunde 19830601

• Treatment of inborn errors of urea synthesis: activation of alternative pathways of waste nitrogen synthesis and excretion.

  The New England journal of medicine 19820610