3736-77-4 | 2,2'-Anhydro-1(B-D-arabinofuranosyl)uracil

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$15.00	$10.00
1g	95%	in stock	$16.00	$11.00
5g	95%	in stock	$20.00	$14.00
10g	95%	in stock	$25.00	$17.00
25g	95%	in stock	$45.00	$31.00
100g	95%	in stock	$155.00	$108.00
500g	95%	in stock	$558.00	$390.00

Description

• Catalog Number: AB52211
• Chemical Name: 2,2'-Anhydro-1(B-D-arabinofuranosyl)uracil
• CAS Number: 3736-77-4
• Molecular Formula: C9H10N2O5
• Molecular Weight: 226.1861
• MDL Number: MFCD00004945
• SMILES: OC[C@H]1O[C@@H]2[C@H]([C@@H]1O)Oc1n2ccc(=O)n1

Computed Properties

• Complexity: 393
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: -2.5

Literature

• An efficient synthetic approach to 6,5'-(S)- and 6,5'-(R)-cyclouridine.

  Chemical communications (Cambridge, England) 20120607

• Influence of conformationally restricted pyrimidines on the activity of 10-23 DNAzymes.

  Bioorganic & medicinal chemistry 20120415

• Synthesis and hybridization properties of 2'-O-methylated oligoribonucleotides incorporating 2'-O-naphthyluridines.

  Organic & biomolecular chemistry 20110107

• The X-ray structure of Salmonella typhimurium uridine nucleoside phosphorylase complexed with 2,2'-anhydrouridine, phosphate and potassium ions at 1.86 A resolution.

  Acta crystallographica. Section D, Biological crystallography 20100101

• Microwave-assisted synthesis of 2'-O-aryluridine derivatives.

  Organic letters 20091217

• Synthesis and properties of new RNA molecules incorporating 2'-O-aryluridine derivatives.

  Nucleic acids symposium series (2004) 20090101

• Isolation, crystallization and preliminary crystallographic analysis of Salmonella typhimurium uridine phosphorylase crystallized with 2,2'-anhydrouridine.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20071001

• Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system.

  Bioorganic & medicinal chemistry 20050301

• Efficient synthesis of 2',3'-dideoxy-2'-amino-3'-thiouridine.

  Organic letters 20040624

• Antiviral and antineoplastic activities of pyrimidine arabinosyl nucleosides and their 5'-amino derivatives.

  Journal of medicinal chemistry 19791001