375815-87-5 | Varenicline tartrate

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$7.00	$5.00
5mg	98%	in stock	$14.00	$10.00
10mg	98%	in stock	$18.00	$13.00
25mg	98%	in stock	$22.00	$16.00
100mg	98%	in stock	$34.00	$24.00
1g	98%	in stock	$181.00	$127.00

Description

• Catalog Number: AF56673
• Chemical Name: Varenicline tartrate
• CAS Number: 375815-87-5
• Molecular Formula: C17H19N3O6
• Molecular Weight: 361.3493
• MDL Number: MFCD08460603
• SMILES: N1C[C@@H]2C[C@H](C1)c1c2cc2c(c1)nccn2.O[C@H]([C@H](C(=O)O)O)C(=O)O

Computed Properties

• Complexity: 388
• Covalently-Bonded Unit Count: 2
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 26
• Hydrogen Bond Acceptor Count: 9
• Hydrogen Bond Donor Count: 5
• Rotatable Bond Count: 3
• Undefined Atom Stereocenter Count: 2

Literature

• Varenicline promotes endothelial cell migration by lowering vascular endothelial-cadherin levels via the activated α7 nicotinic acetylcholine receptor-mitogen activated protein kinase axis.

  Toxicology 20170901

• Varenicline enhances oxidized LDL uptake by increasing expression of LOX-1 and CD36 scavenger receptors through α(7) nAChR in macrophages.

  Toxicology 20170401

• Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.

  Chemical research in toxicology 20150518

• Organic cation transporter variation and response to smoking cessation therapies.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20141201

• Comparative pathophysiology, toxicology, and human cancer risk assessment of pharmaceutical-induced hibernoma.

  Toxicology and applied pharmacology 20131215

• Effects of nicotinic acetylcholine receptor agonists on cognition in rhesus monkeys with a chronic cocaine self-administration history.

  Neuropharmacology 20130101

• The effect of smoking cessation pharmacotherapies on pancreatic beta cell function.

  Toxicology and applied pharmacology 20121115

• Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by α3β4α5 nicotinic acetylcholine receptors.

  Neuropharmacology 20121101

• Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain.

  The Journal of pharmacology and experimental therapeutics 20121101

• Strategies to help a smoker who is struggling to quit.

  JAMA 20121017

• An economic evaluation based on a randomized placebo-controlled trial of varenicline in smokers with cardiovascular disease: results for Belgium, Spain, Portugal, and Italy.

  European journal of preventive cardiology 20121001

• Varenicline decreases nicotine self-administration and cue-induced reinstatement of nicotine-seeking behaviour in rats when a long pretreatment time is used.

  The international journal of neuropsychopharmacology 20121001

• Project Impact: a pharmacotherapy pilot trial investigating the abstinence and treatment adherence of Latino light smokers.

  Journal of substance abuse treatment 20121001

• Varenicline induced psychosis in schizophrenia.

  The Australian and New Zealand journal of psychiatry 20121001

• Varenicline decreases alcohol consumption in heavy-drinking smokers.

  Psychopharmacology 20121001

• Effects of 21 days of varenicline versus placebo on smoking behaviors and urges among non-treatment seeking smokers.

  Journal of psychopharmacology (Oxford, England) 20121001

• Adverse neuropsychiatric events associated with varenicline use in veterans: a case series.

  Issues in mental health nursing 20121001

• Characteristics of COPD smokers and effectiveness and safety of smoking cessation medications.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120901

• Adherence to varenicline among African American smokers: an exploratory analysis comparing plasma concentration, pill count, and self-report.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120901

• Effects of the combination of metyrapone and oxazepam on intravenous nicotine self-administration in rats.

  Psychopharmacology 20120901

• Impact of varenicline on cue-specific craving assessed in the natural environment among treatment-seeking smokers.

  Psychopharmacology 20120901

• The effects of varenicline on attention and inhibitory control among treatment-seeking smokers.

  Psychopharmacology 20120901

• Use of an α3β4 nicotinic acetylcholine receptor subunit concatamer to characterize ganglionic receptor subtypes with specific subunit composition reveals species-specific pharmacologic properties.

  Neuropharmacology 20120901

• The antinociceptive effects of nicotinic partial agonists varenicline and sazetidine-A in murine acute and tonic pain models.

  The Journal of pharmacology and experimental therapeutics 20120901

• Comparisons of high-dose and combination nicotine replacement therapy, varenicline, and bupropion for smoking cessation: a systematic review and multiple treatment meta-analysis.

  Annals of medicine 20120901

• Varenicline for smoking cessation: nausea severity and variation in nicotinic receptor genes.

  The pharmacogenomics journal 20120801

• Varenicline is a potent partial agonist at α6β2* nicotinic acetylcholine receptors in rat and monkey striatum.

  The Journal of pharmacology and experimental therapeutics 20120801

• Do package inserts reflect symptoms experienced in practice?: assessment using an automated phone pharmacovigilance system with varenicline and zolpidem in a primary care setting.

  Drug safety 20120801

• Efficacy and safety of pharmacotherapy for smoking cessation among pregnant smokers: a meta-analysis.

  BJOG : an international journal of obstetrics and gynaecology 20120801

• Cost-effectiveness of varenicline versus bupropion, nicotine-replacement therapy, and unaided cessation in Greece.

  Clinical therapeutics 20120801

• Health impact of smoking and smoking cessation strategies: current evidence.

  British journal of community nursing 20120801

• Does varenicline worsen psychiatric symptoms in patients with schizophrenia or schizoaffective disorder? A review of published studies.

  The Journal of clinical psychiatry 20120801

• Structural characterization of binding mode of smoking cessation drugs to nicotinic acetylcholine receptors through study of ligand complexes with acetylcholine-binding protein.

  The Journal of biological chemistry 20120706

• Prescribing of nicotine replacement therapy to cardiovascular disease patients in England.

  Addiction (Abingdon, England) 20120701

• Varenicline increases in vivo striatal dopamine D2/3 receptor binding: an ultra-high-resolution pinhole [123I]IBZM SPECT study in rats.

  Nuclear medicine and biology 20120701

• Epistaxis and other haemorrhagic events associated with the smoking cessation medicine varenicline: a case series from two national pharmacovigilance centres.

  European journal of clinical pharmacology 20120701

• Effectiveness of varenicline for smoking cessation at 2 urban academic health centers.

  European journal of internal medicine 20120701

• Varenicline blocks β2*-nAChR-mediated response and activates β4*-nAChR-mediated responses in mice in vivo.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120601

• A single administration of low-dose varenicline saturates α4β2* nicotinic acetylcholine receptors in the human brain.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120601

• Pharmacologic characterization of a nicotine-discriminative stimulus in rhesus monkeys.

  The Journal of pharmacology and experimental therapeutics 20120601

• A pilot test of a combined tobacco dependence treatment and lung cancer screening program.

  Lung cancer (Amsterdam, Netherlands) 20120501

• Very low rate and light smokers: smoking patterns and cessation-related behaviour in England, 2006-11.

  Addiction (Abingdon, England) 20120501

• Varenicline potentiates alcohol-induced negative subjective responses and offsets impaired eye movements.

  Alcoholism, clinical and experimental research 20120501

• [Effectiveness and safety of varenicline for smoking cessation].

  Deutsche medizinische Wochenschrift (1946) 20120501

• A randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of varenicline for smoking cessation in patients with schizophrenia or schizoaffective disorder.

  The Journal of clinical psychiatry 20120501

• Nicotine receptor partial agonists for smoking cessation.

  The Cochrane database of systematic reviews 20120418

• Changes in health-related quality of life with smoking cessation treatment.

  European journal of public health 20120401

• Plasma levels of metabolites of catecholamine in nicotine-dependent patients treated with varenicline.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120401

• Efficacy and tolerability of pharmacotherapies to aid smoking cessation in adolescents.

  Paediatric drugs 20120401

• Promoting smoking cessation.

  American family physician 20120315

• Cost-effectiveness of tobacco control policies in Vietnam: the case of personal smoking cessation support.

  Addiction (Abingdon, England) 20120301

• Varenicline dose dependently enhances responding for nonpharmacological reinforcers and attenuates the reinforcement-enhancing effects of nicotine.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120301

• A randomized placebo-controlled trial of varenicline for smoking cessation allowing flexible quit dates.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120301

• Smoking cessation after brain damage does not lead to increased depression: implications for understanding the psychiatric complications of varenicline.

  Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 20120301

• A randomized trial of varenicline (Chantix) for the treatment of spinocerebellar ataxia type 3.

  Neurology 20120221

• Pfizer advertises smoking cessation drug despite health warnings.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20120207

• Varenicline versus bupropion XL for smoking cessation in older adolescents: a randomized, double-blind pilot trial.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120201

• Results of an initial clinical trial of varenicline for the treatment of cocaine dependence.

  Drug and alcohol dependence 20120201

• Effects of varenicline and bupropion on cognitive processes among nicotine-deprived smokers.

  Experimental and clinical psychopharmacology 20120201

• Adjunctive varenicline treatment with antipsychotic medications for cognitive impairments in people with schizophrenia: a randomized double-blind placebo-controlled trial.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120201

• Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120201

• The effects of extended pre-quit varenicline treatment on smoking behavior and short-term abstinence: a randomized clinical trial.

  Clinical pharmacology and therapeutics 20120201

• Quitting smoking with varenicline: parallel, randomised efficacy trial in Iran.

  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20120201

• Grover disease may result from the impairment of keratinocytic cholinergic receptors.

  Journal of the American Academy of Dermatology 20120201

• Systematic review of the cost-effectiveness of varenicline vs. bupropion for smoking cessation.

  International journal of clinical practice 20120201

• Cost-effectiveness analysis of varenicline versus existing smoking cessation strategies in Central America and the Caribbean using the BENESCO model.

  Hospital practice (1995) 20120201

• Cost analysis of varenicline versus bupropion, nicotine replacement therapy, and unaided cessation in Nicaragua.

  Hospital practice (1995) 20120201

• Varenicline: aggression and homicidal ideation.

  Prescrire international 20120201

• The pain of giving up smoking.

  International journal of cardiology 20120126

• [Smoking cessation in medical practice--new possibilities?].

  Revue medicale suisse 20120125

• New reports examine psychiatric risks of varenicline for smoking cessation.

  JAMA 20120111

• Varenicline as a smoking cessation aid in schizophrenia: effects on smoking behavior and reward sensitivity.

  Psychopharmacology 20120101

• Safety and tolerability of varenicline tartrate (Champix(®)/Chantix(®)) for smoking cessation in HIV-infected subjects: a pilot open-label study.

  AIDS patient care and STDs 20120101

• Cardiovascular events in patients taking varenicline: a case series from intensive postmarketing surveillance in New Zealand.

  Drug safety 20120101

• Varenicline precipitating psychosis in a patient with no previous psychiatric history: a case report of a Spanish patient who was later diagnosed with paranoid personality disorder.

  Clinical schizophrenia & related psychoses 20120101

• Real world evaluation of three models of NHS smoking cessation service in England.

  BMC research notes 20120101

• Varenicline in stopping long-term nicotine use.

  The American journal on addictions 20120101

• Varenicline.

  Profiles of drug substances, excipients, and related methodology 20120101

• Risk of cardiovascular serious adverse events associated with varenicline use for tobacco cessation: systematic review and meta-analysis.

  BMJ (Clinical research ed.) 20120101

• Drug-induced liver injury due to varenicline: a case report.

  BMC gastroenterology 20120101

• Economic impact of delays in listing decisions by provincial drug plans after a positive Common Drug Review recommendation: the case of a smoking-cessation treatment.

  Healthcare quarterly (Toronto, Ont.) 20120101

• Use of the Patient Health Questionnaire-2 to predict suicidal ideations in patients taking varenicline.

  The American journal on addictions 20120101

• A novel recruitment message to increase enrollment into a smoking cessation treatment program: preliminary results from a randomized trial.

  Health communication 20111201

• Effects of moderate-dose treatment with varenicline on neurobiological and cognitive biomarkers in smokers and nonsmokers with schizophrenia or schizoaffective disorder.

  Archives of general psychiatry 20111201

• Tobacco dependence treatment for hospitalized smokers: a randomized, controlled, pilot trial using varenicline.

  Addictive behaviors 20111201

• Efficacy of a flexible quit date versus an a priori quit date approach to smoking cessation: a cross-study analysis.

  Addictive behaviors 20111201

• A cost-effectiveness model of smoking cessation based on a randomised controlled trial of varenicline versus placebo in patients with chronic obstructive pulmonary disease.

  Expert opinion on pharmacotherapy 20111201

• [The evaluation of strengthened psychological and behavioral intervention in smoking cessation clinics].

  Zhonghua nei ke za zhi 20111201

• Varenicline prevents affective and cognitive exacerbation during smoking abstinence in male patients with schizophrenia.

  Psychiatry research 20111130

• Quantification of nicotine, cotinine, trans-3'-hydroxycotinine and varenicline in human plasma by a sensitive and specific UPLC-tandem mass-spectrometry procedure for a clinical study on smoking cessation.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115

• Unichiral 2-(2'-pyrrolidinyl)-1,4-benzodioxanes: the 2R,2'S diastereomer of the N-methyl-7-hydroxy analogue is a potent α4β2- and α6β2-nicotinic acetylcholine receptor partial agonist.

  Journal of medicinal chemistry 20111110

• Varenicline effects on craving, cue reactivity, and smoking reward.

  Psychopharmacology 20111101

• Lung function and respiratory symptoms in a 1-year randomized smoking cessation trial of varenicline in COPD patients.

  Respiratory medicine 20111101

• The smoking cessation drug varenicline improves deficient P20-N40 inhibition in DBA/2 mice.

  Pharmacology, biochemistry, and behavior 20111101

• Effects of varenicline on the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys.

  The Journal of pharmacology and experimental therapeutics 20111101

• [Good effect of varenicline in snuff use cessation. Double-blind placebo controlled comparative study].

  Lakartidningen 20111101

• The effect of varenicline on heart rate variability in healthy smokers and nonsmokers.

  Autonomic neuroscience : basic & clinical 20111028

• Cost effectiveness of interventions to reduce relapse to smoking following smoking cessation.

  Addiction (Abingdon, England) 20111001

• The impact of the introduction of smoke-free legislation on prescribing of stop-smoking medications in England.

  Addiction (Abingdon, England) 20111001

• Efficacy of varenicline to prompt quit attempts in smokers not currently trying to quit: a randomized placebo-controlled trial.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20111001

• Patterns of nicotinic receptor antagonism: nicotine discrimination studies.

  The Journal of pharmacology and experimental therapeutics 20111001

• Varenicline is a potent agonist of the human 5-hydroxytryptamine3 receptor.

  The Journal of pharmacology and experimental therapeutics 20111001

• Observational study of safety and efficacy of varenicline for smoking cessation among Filipino smokers.

  Current medical research and opinion 20111001

• Nicotine receptor partial agonists for smoking cessation.

  American family physician 20111001

• More evidence that varenicline harms the heart.

  The Harvard mental health letter 20111001

• A comparison of brain and behavioral effects of varenicline and nicotine in rats.

  Behavioural brain research 20110930

• Clinical practice. Treating smokers in the health care setting.

  The New England journal of medicine 20110929

• Risk of serious adverse cardiovascular events associated with varenicline: a systematic review and meta-analysis.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

• Varenicline for smoking cessation: is it a heartbreaker?

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

• Varenicline: quantifying the risk.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

• Varenicline: quantifying the risk.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

• Varenicline: quantifying the risk.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

• Varenicline: quantifying the risk.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

• Varenicline: quantifying the risk.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

• Varenicline: cardiovascular safety.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

• [Abstinence rates with varenicline compared to bupropion and nicotine replacement therapy for quitting smoking in primary care].

  Atencion primaria 20110901

• Dissociation between duration of action in the forced swim test in mice and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5-I-A85380.

  Psychopharmacology 20110901

• A pilot clinical trial of varenicline for smoking cessation in black smokers.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110901

• A pilot study of the efficacy of varenicline for the treatment of smokeless tobacco users in Midwestern United States.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110901

• Did the introduction of varenicline in England substitute for or add to the use of other smoking cessation medications?

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110901

• Psychiatric adverse events associated with varenicline: an intensive postmarketing prospective cohort study in New Zealand.

  Drug safety 20110901

• In brief: Cardiovascular safety of varenicline (Chantix).

  The Medical letter on drugs and therapeutics 20110822

• Varenicline for tobacco dependence: panacea or plight?

  Expert opinion on pharmacotherapy 20110801

• [Clinical study of smoking cessation clinic subjects].

  Nihon Jibiinkoka Gakkai kaiho 20110801

• Varenicline attenuates cue-induced relapse to alcohol, but not nicotine seeking, while reducing inhibitory response control.

  Psychopharmacology 20110701

• Effectiveness of varenicline for smoking cessation: a 1-year follow-up study.

  Journal of substance abuse treatment 20110701

• Varenicline, a partial agonist at neuronal nicotinic acetylcholine receptors, reduces nicotine-induced increases in 20% ethanol operant self-administration in Sprague-Dawley rats.

  Addiction biology 20110701

• Prescribing of smoking cessation medication in England since the introduction of varenicline.

  Addiction (Abingdon, England) 20110701

• The sensitizing effect of acute nicotine on amphetamine-stimulated behavior and dopamine efflux requires activation of β2 subunit-containing nicotinic acetylcholine receptors and glutamate N-methyl-D-aspartate receptors.

  Neuropharmacology 20110601

• A preliminary investigation of varenicline for heavy drinking smokers.

  Psychopharmacology 20110601

• A double-blind randomized placebo-controlled pilot study of neuropsychiatric adverse events in abstinent smokers treated with varenicline or placebo.

  Biological psychiatry 20110601

• Selective α4β2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110601

• Varenicline for smoking cessation in people with schizophrenia: a double blind randomized pilot study.

  Schizophrenia research 20110601

• Varenicline induced mania in a 51 year old patient without history of bipolar illness.

  Progress in neuro-psychopharmacology & biological psychiatry 20110601

• A discrete-event simulation of smoking-cessation strategies based on varenicline pivotal trial data.

  PharmacoEconomics 20110601

• A case of late-life onset mania during Varenicline assisted smoking cessation.

  International journal of geriatric psychiatry 20110601

• A smoking cessation intervention for thoracic surgery and oncology clinics: a pilot trial.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110601

• Varenicline and the evaluation of neuropsychiatric adverse events in smokers.

  Biological psychiatry 20110601

• Core modification of cytisine: a modular synthesis.

  Angewandte Chemie (International ed. in English) 20110523

• Effects of varenicline on smoking cue–triggered neural and craving responses.

  Archives of general psychiatry 20110501

• Nicotinic receptor agonists decrease L-dopa-induced dyskinesias most effectively in partially lesioned parkinsonian rats.

  Neuropharmacology 20110501

• Electrophysiological perspectives on the therapeutic use of nicotinic acetylcholine receptor partial agonists.

  The Journal of pharmacology and experimental therapeutics 20110501

• Utilization of services in a randomized trial testing phone- and web-based interventions for smoking cessation.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110501

• Adherence to varenicline in the COMPASS smoking cessation intervention trial.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110501

• Treatment of nicotine dependence with Chantix (varenicline).

  Texas dental journal 20110501

• Use of varenicline for 4 weeks before quitting smoking: decrease in ad lib smoking and increase in smoking cessation rates.

  Archives of internal medicine 20110425

• Smoking cessation interventions: a primer for physicians: Comment on 'Use of varenicline for 4 weeks before quitting smoking'.

  Archives of internal medicine 20110425

• [Smoking cessation--assistance for the general practitioner].

  MMW Fortschritte der Medizin 20110407

• Pharmacokinetics, safety, and tolerability following multiple oral doses of varenicline under various titration schedules in elderly nonsmokers.

  Journal of clinical pharmacology 20110401

• Single- and multiple-dose pharmacokinetics of the selective nicotinic receptor partial agonist, varenicline, in healthy Japanese adult smokers.

  Journal of clinical pharmacology 20110401

• A review of cost-effectiveness of varenicline and comparison of cost-effectiveness of treatments for major smoking-related morbidities.

  Journal of evaluation in clinical practice 20110401

• Effectiveness of varenicline as an aid to smoking cessation: results of an inter-European observational study.

  Current medical research and opinion 20110401

• What justifies a placebo-controlled trial of Varenicline for smoking cessation in patients with COPD?

  Chest 20110401

• Effects of varenicline in adult smokers: a multinational, 24-week, randomized, double-blind, placebo-controlled study.

  Clinical therapeutics 20110401

• Smoking cessation pharmacotherapy: a concise overview.

  Advance for NPs & PAs 20110401

• Breaking free from nicotine dependence. A combination of strategies boosts the odds of success.

  The Harvard mental health letter 20110401

• Clinical shorts.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110322

• Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotine.

  Journal of medicinal chemistry 20110310

• Effects of varenicline on smoking cessation in patients with mild to moderate COPD: a randomized controlled trial.

  Chest 20110301

• Abstinence and psychological distress in co-morbid smokers using various pharmacotherapies.

  Drug and alcohol dependence 20110301

• The effects of nicotine, varenicline, and cytisine on schedule-controlled responding in mice: differences in α4β2 nicotinic receptor activation.

  European journal of pharmacology 20110301

• Nicotine dependence: health consequences, smoking cessation therapies, and pharmacotherapy.

  Primary care 20110301

• Interventions for smokeless tobacco use cessation.

  The Cochrane database of systematic reviews 20110216

• Nicotine receptor partial agonists for smoking cessation.

  The Cochrane database of systematic reviews 20110216

• Varenicline blocks nicotine intake in rats with extended access to nicotine self-administration.

  Psychopharmacology 20110201

• Dose-dependent and sustained effects of varenicline on dopamine D2/3 receptor availability in rats.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20110201

• Adherence to and reasons for premature discontinuation from stop-smoking medications: data from the ITC Four-Country Survey.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110201

• Australia's experience with varenicline: usage, costs and adverse reactions.

  Addiction (Abingdon, England) 20110201

• Adynamic ileus induced by varenicline.

  Current drug safety 20110201

• Integrating results from smoking cessation drug research and development into clinical occupational health practice.

  AAOHN journal : official journal of the American Association of Occupational Health Nurses 20110201

• Effects of copayment on initiation of smoking cessation pharmacotherapy: an analysis of varenicline reversed claims.

  Clinical therapeutics 20110201

• [Pharmacotherapies for nicotine dependence: review of scientific evidence. Spanish Society of Smoking Specialists: recommendations about election and individualization].

  Medicina clinica 20110129

• Varenicline for tobacco dependence treatment in recovering alcohol-dependent smokers: an open-label pilot study.

  Journal of substance abuse treatment 20110101

• Effect of co-administration of varenicline and antidepressants on extracellular monoamine concentrations in rat prefrontal cortex.

  Neurochemistry international 20110101

• Parallel anxiolytic-like effects and upregulation of neuronal nicotinic acetylcholine receptors following chronic nicotine and varenicline.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110101

• Impact of genetic variability in nicotinic acetylcholine receptors on nicotine addiction and smoking cessation treatment.

  Current medicinal chemistry 20110101

• Functional interactions of fibrillar and oligomeric amyloid-β with alpha7 nicotinic receptors in Alzheimer's disease.

  Journal of Alzheimer's disease : JAD 20110101

• Counselors' knowledge of the adoption of tobacco cessation medications in substance abuse treatment programs.

  The American journal on addictions 20110101

• Nicotinic acetylcholine receptors containing the α4 subunit are critical for the nicotine-induced reduction of acute voluntary ethanol consumption.

  Channels (Austin, Tex.) 20110101

• Pharmacotherapy for smoking.

  Canadian family physician Medecin de famille canadien 20110101

• Usage patterns of stop smoking medications in Australia, Canada, the United Kingdom, and the United States: findings from the 2006-2008 International Tobacco Control (ITC) Four Country Survey.

  International journal of environmental research and public health 20110101

• Correlation between willing to smoking cessation and treatment outcome of health care workers in Thailandt.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20110101

• Pharmacotherapy for smoking cessation: present and future.

  Current pharmaceutical design 20110101

• Culturally-tailored smoking cessation for American Indians: study protocol for a randomized controlled trial.

  Trials 20110101

• A manic episode in a 64-year-old man: an adverse effect of varenicline.

  General hospital psychiatry 20110101

• The management of tobacco smoking.

  Cardiovascular journal of Africa 20110101

• Varenicline induces manic relapse in bipolar disorder.

  General hospital psychiatry 20110101

• Gastrointestinal adverse effects of varenicline at maintenance dose: a meta-analysis.

  BMC clinical pharmacology 20110101

• Suicidal behavior and depression in smoking cessation treatments.

  PloS one 20110101

• Effects of smoking cessation on central blood pressure and arterial stiffness.

  Vascular health and risk management 20110101

• Adverse effects and tolerability of medications for the treatment of tobacco use and dependence.

  Drugs 20101224

• Nicotine receptor partial agonists for smoking cessation.

  The Cochrane database of systematic reviews 20101208

• Drug treatment for users of smokeless tobacco.

  BMJ (Clinical research ed.) 20101206

• The high-affinity nAChR partial agonists varenicline and sazetidine-A exhibit reinforcing properties in rats.

  Progress in neuro-psychopharmacology & biological psychiatry 20101201

• Drug discrimination in methamphetamine-trained rats: effects of cholinergic nicotinic compounds.

  The Journal of pharmacology and experimental therapeutics 20101201

• The nicotinic acetylcholine receptor partial agonist varenicline increases the ataxic and sedative-hypnotic effects of acute ethanol administration in C57BL/6J mice.

  Alcoholism, clinical and experimental research 20101201

• Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis.

  Trends in pharmacological sciences 20101201

• A review of the clinical pharmacokinetics and pharmacodynamics of varenicline for smoking cessation.

  Clinical pharmacokinetics 20101201

• Varenicline-induced grand mal seizure.

  Epileptic disorders : international epilepsy journal with videotape 20101201

• Thiopurine S-methyltransferase deficiency associated with a novel mutation.

  Inflammatory bowel diseases 20101101

• Immediate versus delayed quitting and rates of relapse among smokers treated successfully with varenicline, bupropion SR or placebo.

  Addiction (Abingdon, England) 20101101

• Mental health stability in veterans with posttraumatic stress disorder receiving varenicline.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101101

• [Sustainable efficacy of oral varenicline for smoking cessation].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20101101

• Comparison of available treatments for tobacco addiction.

  Current psychiatry reports 20101001

• A pilot study to assess smokeless tobacco use reduction with varenicline.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20101001

• Nicotine gum dependence treated with varenicline--a case report.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20101001

• Clinical experience of varenicline for smoking cessation.

  The clinical respiratory journal 20101001

• A brief review of pharmacotherapeutic treatment options in smoking cessation: bupropion versus varenicline.

  Journal of the American Academy of Nurse Practitioners 20101001

• Relapse prevention in UK Stop Smoking Services: current practice, systematic reviews of effectiveness and cost-effectiveness analysis.

  Health technology assessment (Winchester, England) 20101001

• Varenicline (champix)-associated manic relapse in bipolar affective disorder.

  Irish medical journal 20101001

• Utilization of the smoking cessation medicine varenicline: an intensive post-marketing study in New Zealand.

  Pharmacoepidemiology and drug safety 20100901

• Thoughts and acts of aggression/violence toward others reported in association with varenicline.

  The Annals of pharmacotherapy 20100901

• Varenicline treatment for smoking cessation in Asian populations: a pooled analysis of placebo-controlled trials conducted in six Asian countries.

  Current medical research and opinion 20100901

• The safety and efficacy of varenicline in cocaine using smokers maintained on methadone: a pilot study.

  The American journal on addictions 20100901

• Pharmacoeconomic spotlight on varenicline as an aid to smoking cessation.

  CNS drugs 20100901

• Utilization management for smoking cessation pharmacotherapy: varenicline rejected claims analysis.

  The American journal of managed care 20100901

• Electroconvulsive therapy (ECT) effective for psychotic recrudescence and suicidality after varenicline adjunctive therapy for smoking cessation in a schizoaffective patient.

  Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20100901

• Letter by Smolderen and Pelle regarding article, 'Efficacy and safety of varenicline for smoking cessation in patients with cardiovascular disease: a randomized trial'.

  Circulation 20100831

• Drug safety crackdown revs up.

  Nature 20100805

• Nicotinic partial agonists varenicline and sazetidine-A have differential effects on affective behavior.

  The Journal of pharmacology and experimental therapeutics 20100801

• Varenicline and mecamylamine attenuate locomotor sensitization and cross-sensitization induced by nicotine and morphine in mice.

  Pharmacology, biochemistry, and behavior 20100801

• Smoking cessation-recent advances.

  Cardiovascular drugs and therapy 20100801

• The use of snus for quitting smoking compared with medicinal products.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20100801

• [The management of patients with nicotine dependence - the role of the general practitioners].

  Therapeutische Umschau. Revue therapeutique 20100801

• [Medical therapy for smoking cessation].

  Therapeutische Umschau. Revue therapeutique 20100801

• [Preventive relapse treatment for tobacco cessation - is it worthwhile?].

  Therapeutische Umschau. Revue therapeutique 20100801

• Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100728

• Cross-validation of a new procedure for early screening of smoking cessation medications in humans.

  Clinical pharmacology and therapeutics 20100701

• Varenicline-induced drug eruption with resulting palmar/plantar hyperhidrosis and dysesthesia.

  Journal of the American Academy of Dermatology 20100701

• Predictors of post-treatment relapse to smoking in successful quitters: pooled data from two phase III varenicline trials.

  Drug and alcohol dependence 20100601

• Varenicline induced polydipsia and hyponatremia in a patient with schizophrenia.

  Schizophrenia research 20100601

• Extinction with varenicline and nornicotine, but not ABT-418, weakens conditioned responding evoked by the interoceptive stimulus effects of nicotine.

  Neuropharmacology 20100601

• Varenicline treatment decreases DNMT1 mRNA expression in lymphocytes of schizophrenic patients who are cigarette smokers.

  Schizophrenia research 20100601

• Smoking outcome by psychiatric history after behavioral and varenicline treatment.

  Journal of substance abuse treatment 20100601

• Characteristics and abstinence outcomes among tobacco quitline enrollees using varenicline or nicotine replacement therapy.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20100601

• Mouse model predicts effects of smoking and varenicline on event-related potentials in humans.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20100601

• Adherence to treatment for tobacco dependence: association with smoking abstinence and predictors of adherence.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20100601

• Varenicline withdrawal-induced delirium with psychosis.

  The American journal of psychiatry 20100601

• Varenicline in smoking cessation.

  Expert review of respiratory medicine 20100601

• Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes.

  The Journal of pharmacology and experimental therapeutics 20100501

• Varenicline use in patients with mental illness: an update of the evidence.

  Expert opinion on drug safety 20100501

• Varenicline's effects on acute smoking behavior and reward and their association with subsequent abstinence.

  Psychopharmacology 20100501

• Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence.

  British journal of pharmacology 20100501

• Behavioral counseling and varenicline treatment for smoking cessation.

  American journal of preventive medicine 20100501

• [Pharmacological profile and clinical findings on varenicline tartrate (Champix tablets)].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100501

• Effects of the alpha4beta2 partial agonist varenicline on brain activity and working memory in abstinent smokers.

  Biological psychiatry 20100415

• Evaluation of varenicline as an aid to smoking cessation in UK general practice - a THIN database study.

  Current medical research and opinion 20100401

• A randomized controlled open comparative trial of varenicline vs nicotine patch in adult smokers: efficacy, safety and withdrawal symptoms (the VN-SEESAW study).

  Circulation journal : official journal of the Japanese Circulation Society 20100401

• Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain.

  Pain 20100401

• Effects of varenicline and mecamylamine on the acquisition, expression, and reinstatement of nicotine-conditioned place preference by drug priming in rats.

  Naunyn-Schmiedeberg's archives of pharmacology 20100401

• Psychiatric adverse events in randomized, double-blind, placebo-controlled clinical trials of varenicline: a pooled analysis.

  Drug safety 20100401

• Varenicline does not increase serum BDNF levels in patients with nicotine dependence.

  Human psychopharmacology 20100401

• Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-(substituted phenyl)epibatidine analogues. Nicotinic partial agonists.

  Journal of natural products 20100326

• Varenicline and pheochromocytoma.

  Annals of internal medicine 20100302

• Cost effectiveness of varenicline versus bupropion and unaided cessation for smoking cessation in a cohort of Finnish adult smokers.

  Current medical research and opinion 20100301

• Modulation of ethanol consumption by genetic and pharmacological manipulation of nicotinic acetylcholine receptors in mice.

  Psychopharmacology 20100301

• Varenicline effects on cocaine self administration and reinstatement behavior.

  Behavioural pharmacology 20100301

• Quantitative assessment of exposure-response relationships for the efficacy and tolerability of varenicline for smoking cessation.

  Clinical pharmacology and therapeutics 20100301

• Neuronal nicotinic acetylcholine receptors as pharmacotherapeutic targets for the treatment of alcohol use disorders.

  CNS & neurological disorders drug targets 20100301

• Smoking cessation intervention: an evidence-based approach.

  Postgraduate medicine 20100301

• Integrating smoking cessation into HIV care.

  AIDS patient care and STDs 20100301

• Rapid and sustained response to a single dose of sertraline in a patient with newly emergent depression during varenicline-assisted smoking cessation.

  CNS spectrums 20100301

• Effect of the alpha4beta2* nicotinic acetylcholine receptor partial agonist varenicline on dopamine release in beta2 knock-out mice with selective re-expression of the beta2 subunit in the ventral tegmental area.

  Neuropharmacology 20100201

• The nicotinic acetylcholine receptor partial agonist varenicline and the treatment of drug dependence: a review.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100201

• The alpha4beta2 nicotinic acetylcholine-receptor partial agonist varenicline inhibits both nicotine self-administration following repeated dosing and reinstatement of nicotine seeking in rats.

  Psychopharmacology 20100201

• Current approaches to pharmacotherapy for smoking cessation.

  Therapeutic advances in respiratory disease 20100201

• Improving the effectiveness of tobacco use cessation (TUC).

  International dental journal 20100201

• Current treatment options in smoking cessation.

  Hospital practice (1995) 20100201

• Varenicline and P50 auditory gating in medicated schizophrenic patients: a pilot study.

  Psychiatry research 20100130

• Varenicline for smoking cessation in patients with coronary heart disease.

  Circulation 20100119

• Efficacy and safety of varenicline for smoking cessation in patients with cardiovascular disease: a randomized trial.

  Circulation 20100119

• Pharmacogenetics of smoking cessation therapy.

  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20100105

• Working memory deficits predict short-term smoking resumption following brief abstinence.

  Drug and alcohol dependence 20100101

• [Tolerability profile of varenicline in current medical practice].

  Presse medicale (Paris, France : 1983) 20100101

• Crossing borders: factors affecting differences in cost-effectiveness of smoking cessation interventions between European countries.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100101

• The cost-effectiveness of an extended course (12+12 weeks) of varenicline compared with other available smoking cessation strategies in the United States: an extension and update to the BENESCO model.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100101

• Varenicline: a pharmacoeconomic review of its use as an aid to smoking cessation.

  PharmacoEconomics 20100101

• [Medications for smoking cessation. New advice concerning important neuropsychiatric effects].

  Perspective infirmiere : revue officielle de l'Ordre des infirmieres et infirmiers du Quebec 20100101

• Non smoking for successful aging: therapeutic perspectives.

  Current pharmaceutical design 20100101

• Varenicline for smokeless tobacco dependence.

  Journal of postgraduate medicine 20100101

• [More or less smoked news].

  Pneumologia (Bucharest, Romania) 20100101

• Stopping smokeless tobacco with varenicline: randomised double blind placebo controlled trial.

  BMJ (Clinical research ed.) 20100101

• Prescription drugs associated with reports of violence towards others.

  PloS one 20100101

• Smoking cessation in patients with chronic kidney disease.

  CANNT journal = Journal ACITN 20100101

• Varenicline and suicide. Safety data from New Zealand.

  BMJ (Clinical research ed.) 20091231

• Cost-effectiveness of varenicline compared with nicotine patches for smoking cessation--results from four European countries.

  European journal of public health 20091201

• Sibutramine for weight gain attenuation during smoking cessation with varenicline: a pilot study.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20091201

• A retrospective poison center review of varenicline-exposed patients.

  The Annals of pharmacotherapy 20091201

• Varenicline and antiretroviral therapy in patients with HIV.

  Journal of acquired immune deficiency syndromes (1999) 20091201

• Varenicline and suicide. Risk of psychiatric side effects with varenicline.

  BMJ (Clinical research ed.) 20091201

• Smoking cessation agents and suicide.

  BMJ (Clinical research ed.) 20091105

• Varenicline attenuates some of the subjective and physiological effects of intravenous nicotine in humans.

  Psychopharmacology 20091101

• What do we know about the role of pharmacotherapy for smoking cessation before or during pregnancy?

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20091101

• [Drug treatment of tobacco dependence].

  Deutsche medizinische Wochenschrift (1946) 20091101

• Population pharmacokinetic analysis of varenicline in adult smokers.

  British journal of clinical pharmacology 20091101

• Nicotine dependence and smoking cessation.

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20091101

• Varenicline-induced acute generalized exanthematous pustulosis.

  Clinical and experimental dermatology 20091001

• Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition.

  Biochemical pharmacology 20091001

• Smoking cessation: how to advise the patient.

  Heart (British Cardiac Society) 20091001

• Acute generalized exanthematous pustulosis caused by varenicline.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20090901

• Acute hepatic injury associated with varenicline in a patient with underlying liver disease.

  The Annals of pharmacotherapy 20090901

• Varenicline increases striatal dopamine D(2/3) receptor binding in rats.

  Addiction biology 20090901

• Varenicline in prevention of relapse to smoking: effect of quit pattern on response to extended treatment.

  Addiction (Abingdon, England) 20090901

• Lambert-Eaton myasthenic syndrome following varenicline (Chantix) use.

  Muscle & nerve 20090901

• Varenicline in the management of smoking cessation: a single technology appraisal.

  Health technology assessment (Winchester, England) 20090901

• Varenicline gets stronger warnings about psychiatric problems, vehicle crashes.

  JAMA 20090826

• Safety of smoking cessation drugs.

  The Medical letter on drugs and therapeutics 20090824

• Are nicotine replacement therapy, varenicline or bupropion options for pregnant mothers to quit smoking? Effects on the respiratory system of the offspring.

  Therapeutic advances in respiratory disease 20090801

• Varenicline reduces alcohol self-administration in heavy-drinking smokers.

  Biological psychiatry 20090715

• Varenicline: a novel pharmacotherapy for smoking cessation.

  Drugs 20090709

• Varenicline augmentation in depressed smokers: an 8-week, open-label study.

  The Journal of clinical psychiatry 20090701

• Tobacco dependence and withdrawal: science base, challenges and opportunities for pharmacotherapy.

  Pharmacology & therapeutics 20090701

• Varenicline attenuates nicotine-enhanced brain-stimulation reward by activation of alpha4beta2 nicotinic receptors in rats.

  Neuropharmacology 20090701

• Worsening psychosis induced by varenicline in a hospitalized psychiatric patient.

  Pharmacotherapy 20090701

• Varenicline overdose in a teenager--a clinical pharmacology perspective.

  Clinical toxicology (Philadelphia, Pa.) 20090701

• Varenicline-induced mixed mood and psychotic episode in a patient with Schizoaffective Disorder.

  CNS spectrums 20090701

• Impact of symptoms experienced by varenicline users on tobacco treatment in a real world setting.

  Journal of substance abuse treatment 20090601

• Does varenicline induce acute interstitial nephritis?

  Mayo Clinic proceedings 20090601

• Varenicline and proximal myopathy.

  The Medical journal of Australia 20090601

• Tobacco use among individuals with intellectual or developmental disabilities: a brief review.

  Intellectual and developmental disabilities 20090601

• Subjective improvement in proprioception in 2 patients with atypical Friedreich ataxia treated with varenicline (Chantix).

  Journal of clinical neuromuscular disease 20090601

• [Current and future medical drugs for smoking cessation].

  Laryngo- rhino- otologie 20090601

• Cost-effectiveness of varenicline for smoking cessation.

  Expert review of pharmacoeconomics & outcomes research 20090601

• Smoking-cessation therapy using varenicline: the cost-utility of an additional 12-week course of varenicline for the maintenance of smoking abstinence.

  Journal of evaluation in clinical practice 20090601

• Varenicline reduced smoking behaviour in a mentally ill person.

  Journal of psychopharmacology (Oxford, England) 20090501

• Persistent genital arousal disorder: a case report in a woman with lifelong PGAD where serendipitous administration of varenicline tartrate resulted in symptomatic improvement.

  The journal of sexual medicine 20090501

• Mood, side-effects and smoking outcomes among persons with and without probable lifetime depression taking varenicline.

  Journal of general internal medicine 20090501

• Cognitive and antismoking effects of varenicline in patients with schizophrenia or schizoaffective disorder.

  Schizophrenia research 20090501

• Combination treatment with varenicline and nicotine replacement therapy.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20090501

• Safety and effectiveness of varenicline in a veteran population with a high prevalence of mental illness.

  The Annals of pharmacotherapy 20090501

• Hallucinations in the context of varenicline withdrawal.

  The American journal of psychiatry 20090501

• Reduced affective symptoms during tobacco dependence treatment with varenicline.

  Addiction (Abingdon, England) 20090501

• Do the 10 UK suicides among those taking the smoking cessation drug varenicline suggest a causal link?

  Addiction (Abingdon, England) 20090501

• Treatment of comorbid tobacco use in people with serious mental illness.

  Journal of psychiatry & neuroscience : JPN 20090501

• Chantix-induced mental status changes in a young healthy female.

  South Dakota medicine : the journal of the South Dakota State Medical Association 20090501

• Findings on alcohol dependence point to promising avenues for targeted therapies.

  JAMA 20090422

• The relevance and treatment of cue-induced cravings in tobacco dependence.

  Journal of substance abuse treatment 20090401

• The smoking cessation medication varenicline attenuates alcohol and nicotine interactions in the rat mesolimbic dopamine system.

  The Journal of pharmacology and experimental therapeutics 20090401

• Smoking in pregnancy and lactation: a review of risks and cessation strategies.

  European journal of clinical pharmacology 20090401

• Varenicline for smoking cessation: a placebo-controlled, randomized study.

  Respirology (Carlton, Vic.) 20090401

• Varenicline overdose in a teenager.

  Clinical toxicology (Philadelphia, Pa.) 20090401

• The pharmacokinetic and tolerability profile of varenicline in healthy Chinese volunteers.

  International journal of clinical pharmacology and therapeutics 20090401

• Two recent updates for psychiatric conditions.

  Journal of child and adolescent psychopharmacology 20090401

• Update on smoking cessation therapies.

  Advances in therapy 20090401

• Real world study to evaluate the effectiveness of varenicline and cognitive-behavioural interventions for smoking cessation.

  International journal of environmental research and public health 20090401

• Smoking cessation: aspects of prevention and therapy. The activity of the Smoking Cessation Center of Parma-Italy.

  Acta bio-medica : Atenei Parmensis 20090401

• Studies linking smoking-cessation drug with suicide risk spark concerns.

  JAMA 20090311

• Varenicline has antidepressant-like activity in the forced swim test and augments sertraline's effect.

  European journal of pharmacology 20090301

• Smoking cessation with varenicline: a suicidal fatality.

  Journal of analytical toxicology 20090301

• Varenicline and bupropion sustained-release combination therapy for smoking cessation.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20090301

• Emerging drugs for the treatment of tobacco dependence.

  Expert opinion on emerging drugs 20090301

• Varenicline: a first-line treatment option for smoking cessation.

  Clinical therapeutics 20090301

• Antismoking drug still recommended to Canadians despite side effects and US advisory.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20090217

• Varenicline for tobacco dependence.

  The New England journal of medicine 20090212

• Varenicline for tobacco dependence.

  The New England journal of medicine 20090212

• A 51-year-old woman with bipolar disorder who wants to quit smoking.

  JAMA 20090204

• Treatment of imbalance with varenicline Chantix(R): report of a patient with fragile X tremor/ataxia syndrome.

  Acta neurologica Scandinavica 20090201

• An algorithm for tailoring pharmacotherapy for smoking cessation: results from a Delphi panel of international experts.

  Tobacco control 20090201

• Interventions for preventing weight gain after smoking cessation.

  The Cochrane database of systematic reviews 20090121

• Varenicline improves mood and cognition during smoking abstinence.

  Biological psychiatry 20090115

• Budgetary impact of varenicline in smoking cessation in the United Kingdom.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20090101

• Effects of the nicotinic receptor partial agonists varenicline and cytisine on the discriminative stimulus effects of nicotine in rats.

  Pharmacology, biochemistry, and behavior 20090101

• Pharmacology of nicotine: addiction, smoking-induced disease, and therapeutics.

  Annual review of pharmacology and toxicology 20090101

• [Modern medical support for smoking cessation].

  Der Internist 20090101

• Update in new medications for primary care.

  Journal of general internal medicine 20090101

• Targeting reward-relevant nicotinic receptors in the discovery of novel pharmacotherapeutic agents to treat tobacco dependence.

  Nebraska Symposium on Motivation. Nebraska Symposium on Motivation 20090101

• New findings on nicotine addiction and treatment.

  Nebraska Symposium on Motivation. Nebraska Symposium on Motivation 20090101

• Quitting smoking without a psychotic break: the potential link between nicotinic acetylcholine receptor partial agonists and neuropsychiatric adverse events.

  Clinical nurse specialist CNS 20090101

• Do implementation issues influence the effectiveness of medications? The case of nicotine replacement therapy and bupropion in UK Stop Smoking Services.

  BMC public health 20090101

• [Varenicline - pharmacological therapy of tobacco dependence].

  Wiener medizinische Wochenschrift (1946) 20090101

• A preliminary benefit-risk assessment of varenicline in smoking cessation.

  Drug safety 20090101

• Pharmacokinetics, safety, and tolerability of varenicline in healthy adolescent smokers: a multicenter, randomized, double-blind, placebo-controlled, parallel-group study.

  Clinical therapeutics 20090101

• Cost-utility analysis of varenicline, an oral smoking-cessation drug, in Japan.

  PharmacoEconomics 20090101

• Successful smoking cessation and improvement of negative symptoms with varenicline in a stable schizophrenia patient.

  The Journal of neuropsychiatry and clinical neurosciences 20090101

• Smoking and chronic obstructive pulmonary disease (COPD). Parallel epidemics of the 21 century.

  International journal of environmental research and public health 20090101

• Safety and drug utilization profile of varenicline as used in general practice in England: interim results from a prescription-event monitoring study.

  Drug safety 20090101

• Varenicline-induced mania in a bipolar patient.

  Clinical neuropharmacology 20090101

• [Cardiac arrest with varenicline: a case report].

  Therapie 20090101

• Treating tobacco dependence in a medical setting.

  CA: a cancer journal for clinicians 20090101

• Cost effectiveness of varenicline in Belgium, compared with bupropion, nicotine replacement therapy, brief counselling and unaided smoking cessation: a BENESCO Markov cost-effectiveness analysis.

  Clinical drug investigation 20090101

• Varenicline and suicidal behaviour: a cohort study based on data from the General Practice Research Database.

  BMJ (Clinical research ed.) 20090101

• [A multidisciplinary approach of nicotine addiction--the new face of the tabaccology conference. Iaşi, June 25-27, 2009].

  Pneumologia (Bucharest, Romania) 20090101

• Practical implementation of varenicline as an aid to smoking cessation in clinical practice.

  Pneumologia (Bucharest, Romania) 20090101

• Regulation of smoking cessation drugs by the Food and Drug Administration.

  Food and drug law journal 20090101

• Clinical utility of varenicline for smokers with medical and psychiatric comorbidity.

  International journal of chronic obstructive pulmonary disease 20090101

• Varenicline: for smoking cessation.

  Kathmandu University medical journal (KUMJ) 20090101

• Evaluation of cost-utility of varenicline compared with existing smoking cessation therapies in South Korea.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20090101

• Cost-effectiveness of pharmacogenetic testing to tailor smoking-cessation treatment.

  The pharmacogenomics journal 20081201

• Effect of varenicline on the acute and repeated locomotor responses to nicotine in rats.

  Synapse (New York, N.Y.) 20081201

• Varenicline-associated acute renal failure.

  The Annals of pharmacotherapy 20081201

• Possible varenicline-induced paranoia and irritability in a patient with major depressive disorder, borderline personality disorder, and methamphetamine abuse in remission.

  Journal of clinical psychopharmacology 20081201

• [Drug treatment for smoking and marijuana abuse].

  Revue des maladies respiratoires 20081201

• [Specific program for smoking cessation: thus your patients become nonsmokers].

  MMW Fortschritte der Medizin 20081113

• Varenicline for tobacco dependence.

  The New England journal of medicine 20081106

• Lack of a pharmacokinetic interaction between a new smoking cessation therapy, varenicline, and digoxin in adult smokers.

  European journal of clinical pharmacology 20081101

• The influence of acute varenicline administration on smoking and eating behavior in humans.

  Pharmacology, biochemistry, and behavior 20081101

• Multimodal techniques for smoking cessation: a review of their efficacy and utilisation and clinical practice guidelines.

  International journal of clinical practice 20081101

• Smoking cessation in pregnancy.

  Expert opinion on drug safety 20081101

• Smoking cessation: new ways to quit.

  Harvard men's health watch 20081101

• Suicidal ideation and varenicline: a possible case of mistaken adverse drug reaction?

  The Journal of clinical psychiatry 20081101

• Varenicline and smokers with mental illnesses.

  Lancet (London, England) 20081004

• Nicotinic receptor partial agonists as novel compounds for the treatment of smoking cessation.

  Expert opinion on investigational drugs 20081001

• Varenicline ameliorates nicotine withdrawal-induced learning deficits in C57BL/6 mice.

  Behavioral neuroscience 20081001

• Pharmacotherapy for smoking cessation.

  Therapeutic advances in respiratory disease 20081001

• [Varenicline for smoking cessation].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20080911

• Neuropsychiatric disturbance after initiation of varenicline in a patient with a history of alcohol abuse and major depression.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080901

• Drugs for tobacco dependence.

  Treatment guidelines from the Medical Letter 20080901

• The risk-benefit balance of varenicline for smoking cessation.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080901

• Varenicline and suicidality: a new era in medication safety surveillance.

  Expert opinion on drug safety 20080901

• First in class.

  Scientific American 20080901

• Smoking cessation: the psychiatrist's role.

  Journal of psychiatry & neuroscience : JPN 20080901

• Varenicline versus transdermal nicotine patch for smoking cessation: results from a randomised open-label trial.

  Thorax 20080801

• Varenicline efficacy and tolerability in a subject with schizophrenia.

  Schizophrenia research 20080801

• The place of varenicline in smoking cessation treatment.

  Thorax 20080801

• Pre-cessation varenicline treatment vs post-cessation NRT: an uneven playing field.

  Thorax 20080801

• Clinically significant outcomes in smoking cessation.

  Thorax 20080801

• Tobacco smoking cessation management: integrating varenicline in current practice.

  Vascular health and risk management 20080801

• Nicotine receptor partial agonists for smoking cessation.

  The Cochrane database of systematic reviews 20080716

• Pharmacotherapies for smoking cessation: a meta-analysis of randomized controlled trials.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20080715

• Varenicline (Chantix) warnings: risk versus benefit.

  The Medical letter on drugs and therapeutics 20080714

• Varenicline ameliorates ethanol-induced deficits in learning in C57BL/6 mice.

  Neurobiology of learning and memory 20080701

• The efficacy and safety of varenicline for smoking cessation using a flexible dosing strategy in adult smokers: a randomized controlled trial.

  Current medical research and opinion 20080701

• Diffuse exanthema in a patient receiving varenicline.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080701

• Clinical inquiries. What are the most effective ways you can help patients stop smoking?

  The Journal of family practice 20080701

• [Champix not suitable for elderly with depression].

  Lakartidningen 20080701

• [Cost effectiveness analysis of varenicline (Champix) for the treatment of smoking in Spain].

  Anales de medicina interna (Madrid, Spain : 1984) 20080701

• Updated US smoking cessation guideline advises counseling, combining therapies.

  JAMA 20080618

• Smoking cessation in pregnancy: why, how, and what next..

  Clinical obstetrics and gynecology 20080601

• Pharmacological effects of nicotine on norepinephrine metabolism in rat brown adipose tissue: relevance to nicotinic therapies for smoking cessation.

  Toxicologic pathology 20080601

• Exacerbation of recurrent depression as a result of treatment with varenicline.

  The American journal of psychiatry 20080601

• Varenicline-induced mixed mood and psychotic episode in a patient with a past history of depression.

  CNS spectrums 20080601

• Which drug to be used in smoking cessation?

  Polskie Archiwum Medycyny Wewnetrznej 20080601

• Varenicline treatment for smokers with schizophrenia: a case series.

  The Journal of clinical psychiatry 20080601

• Smoking cessation therapy with varenicline.

  International journal of chronic obstructive pulmonary disease 20080601

• Varenicline as compared to bupropion in smoking-cessation therapy--cost-utility results for Sweden 2003.

  Respiratory medicine 20080501

• Varenicline may trigger severe hypoglycaemia in Type 1 diabetes.

  Diabetic medicine : a journal of the British Diabetic Association 20080501

• Empowering dental hygienists: tobacco cessation resources.

  International journal of dental hygiene 20080501

• Varenicline for smoking cessation.

  Drug and therapeutics bulletin 20080501

• [The ABC of smoking cessation].

  Medizinische Monatsschrift fur Pharmazeuten 20080501

• New kid on the block: Chantix for smoking cessation.

  Texas dental journal 20080501

• Stat bite: Medicaid coverage of tobacco-dependence treatments.

  Journal of the National Cancer Institute 20080402

• N-methylation and N-formylation of a secondary amine drug (varenicline) in an osmotic tablet.

  Journal of pharmaceutical sciences 20080401

• Effect of human renal cationic transporter inhibition on the pharmacokinetics of varenicline, a new therapy for smoking cessation: an in vitro-in vivo study.

  Clinical pharmacology and therapeutics 20080401

• Effect of varenicline and bupropion SR on craving, nicotine withdrawal symptoms, and rewarding effects of smoking during a quit attempt.

  Psychopharmacology 20080401

• Human abuse liability of the smoking cessation drug varenicline in smokers and nonsmokers.

  Clinical pharmacology and therapeutics 20080401

• Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction.

  Clinical pharmacology and therapeutics 20080401

• Breaking away from a narrow prescribing protocol for medicinal nicotine.

  Addiction (Abingdon, England) 20080401

• Efficacy and safety of varenicline for smoking cessation.

  The American journal of medicine 20080401

• Drug addiction: a critical problem calling for novel solutions.

  Clinical pharmacology and therapeutics 20080401

• Smoking cessation 2008.

  IDrugs : the investigational drugs journal 20080401

• What's new in clinical pharmacology and therapeutics.

  WMJ : official publication of the State Medical Society of Wisconsin 20080401

• FDA warns of adverse events linked to smoking cessation drug and antiepileptics.

  JAMA 20080312

• Comment and reply: A double-blind study evaluating the long-term safety of varenicline for smoking cessation.

  Current medical research and opinion 20080201

• Hypomania with agitation associated with varenicline use in bipolar II disorder.

  The Annals of pharmacotherapy 20080201

• Smoking cessation and lung cancer: oncology nurses can make a difference.

  Seminars in oncology nursing 20080201

• Varenicline: a new pharmaceutical approach to smoking cessation.

  Nursing for women's health 20080201

• Cost-effectiveness of varenicline compared with bupropion, NRT, and nortriptyline for smoking cessation in the Netherlands.

  Current medical research and opinion 20080101

• Varenicline in the routine treatment of tobacco dependence: a pre-post comparison with nicotine replacement therapy and an evaluation in those with mental illness.

  Addiction (Abingdon, England) 20080101

• An update on therapeutics for tobacco dependence.

  Expert opinion on pharmacotherapy 20080101

• Smoking cessation--what works?

  Australian family physician 20080101

• Varenicline versus bupropion SR or placebo for smoking cessation: a pooled analysis.

  American journal of health behavior 20080101

• Cost-utility analysis of varenicline versus existing smoking cessation strategies using the BENESCO Simulation model: application to a population of US adult smokers.

  PharmacoEconomics 20080101

• Chantix.

  Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses 20080101

• Varenicline and its role in smoking cessation.

  Preventive cardiology 20080101

• Smoking cessation therapy considerations for patients with chronic kidney disease.

  Nephrology nursing journal : journal of the American Nephrology Nurses' Association 20080101

• Systematic review and meta-analysis of combination therapy for smoking cessation.

  Journal of the American Pharmacists Association : JAPhA 20080101

• [Not smoking, essential for healthy lungs].

  Pharmazie in unserer Zeit 20080101

• Treatment of ataxia and imbalance with varenicline (chantix): report of 2 patients with spinocerebellar ataxia (types 3 and 14).

  Clinical neuropharmacology 20080101

• Smoking cessation in cardiovascular patients.

  Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20080101

• [Pharmacotherapy of smoking cessation with application of nicotine and nicotine free drugs].

  Przeglad lekarski 20080101

• Varenicline and adult ADHD.

  The Journal of neuropsychiatry and clinical neurosciences 20080101

• Varenicline, appetite, and weight reduction.

  The Journal of neuropsychiatry and clinical neurosciences 20080101

• A reader responds to 'Seven pharmacotherapies do promote smoking abstinence at 6 and 12 months'.

  Medscape journal of medicine 20080101

• A longer course of varenicline therapy improves smoking cessation rates.

  Preventive cardiology 20080101

• Which is the best primary medication for long-term smoking cessation--nicotine replacement therapy, bupropion or varenicline?

  Expert opinion on pharmacotherapy 20071201

• Treatment of tobacco dependence: integrating recent progress into practice.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20071120

• [Varenicline--a new drug for smoking cessation].

  Ugeskrift for laeger 20071119

• [New drugs; varenicline].

  Nederlands tijdschrift voor geneeskunde 20071110

• Lack of pharmacokinetic and pharmacodynamic interactions between a smoking cessation therapy, varenicline, and warfarin: an in vivo and in vitro study.

  Journal of clinical pharmacology 20071101

• Smoking cessation: an overview of treatment options with a focus on varenicline.

  Pharmacotherapy 20071101

• Breaking the ties of nicotine dependence.

  The Nurse practitioner 20071101

• Interference with smoking-cessation effects of varenicline after administration of immediate-release amphetamine-dextroamphetamine.

  Pharmacotherapy 20071001

• Smoking cessation: tactics that make a big difference.

  The Journal of family practice 20071001

• A new medication for the worst addiction.

  Current psychiatry reports 20071001

• A second varenicline trial.

  Current psychiatry reports 20071001

• Varenicline as maintenance therapy.

  Current psychiatry reports 20071001

• Treating tobacco dependence in women.

  Journal of women's health (2002) 20071001

• The truth about smoking cessation.

  The Johns Hopkins medical letter health after 50 20071001

• The cost effectiveness of varenicline for smoking cessation.

  Managed care interface 20071001

• A call to action: new treatment options provide even more reasons to intervene in tobacco dependence.

  Nature clinical practice. Cardiovascular medicine 20070901

• [Varenicline].

  Revue de l'infirmiere 20070901

• An evaluation of the OECD 308 water/sediment systems for investigating the biodegradation of pharmaceuticals.

  Environmental science & technology 20070815

• Varenicline-induced manic episode in a patient with bipolar disorder.

  The American journal of psychiatry 20070801

• Exacerbation of schizophrenia by varenicline.

  The American journal of psychiatry 20070801

• Varenicline: progress in smoking cessation treatment.

  Expert opinion on pharmacotherapy 20070801

• Optimizing on smoke free legislation making the most of the opportunity.

  British journal of community nursing 20070801

• Smoking cessation: lessons learned from clinical trial evidence.

  Current opinion in cardiology 20070701

• Rationale, pharmacology and clinical efficacy of partial agonists of alpha4beta2 nACh receptors for smoking cessation.

  Trends in pharmacological sciences 20070701

• Varenicline: the newest agent for smoking cessation.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070701

• The pharmacist's role in tobacco cessation: overview and introduction to the series.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070701

• New non-nicotine drug to help smoking cessation efforts.

  Nursing times 20070601

• Why choose varenicline (chantix) for smoking cessation treatment?

  Issues in mental health nursing 20070601

• Smoking cessation update.

  South Dakota medicine : the journal of the South Dakota State Medical Association 20070601

• [New smoking cessation preparations unsuitable in mental disorders].

  Lakartidningen 20070601

• How well does the new drug varenicline work for people who want to stop smoking?

  The Harvard mental health letter 20070601

• A randomized, placebo-controlled trial of varenicline, a selective alpha4beta2 nicotinic acetylcholine receptor partial agonist, as a new therapy for smoking cessation in Asian smokers.

  Clinical therapeutics 20070601

• Efficacy and tolerability of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, in a 12-week, randomized, placebo-controlled, dose-response study with 40-week follow-up for smoking cessation in Japanese smokers.

  Clinical therapeutics 20070601

• Confirmatory factor analyses and reliability of the modified cigarette evaluation questionnaire.

  Addictive behaviors 20070501

• Comment: Oral varenicline for smoking cessation.

  The Annals of pharmacotherapy 20070401

• A double-blind study evaluating the long-term safety of varenicline for smoking cessation.

  Current medical research and opinion 20070401

• An employer-based cost-benefit analysis of a novel pharmacotherapy agent for smoking cessation.

  Journal of occupational and environmental medicine 20070401

• Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid.

  Neuropharmacology 20070301

• [The path from cigarettes--with support it works better].

  Medizinische Monatsschrift fur Pharmazeuten 20070301

• [Varenicline--a new drug for smoking cessation].

  Medizinische Monatsschrift fur Pharmazeuten 20070301

• The most addictive drug, the most deadly substance: smoking cessation tactics for the busy clinician.

  Primary care 20070301

• [Giving up smoking is crucial for COPD patients].

  MMW Fortschritte der Medizin 20070222

• Ligands selective for alpha4beta2 but not alpha3beta4 or alpha7 nicotinic receptors generalise to the nicotine discriminative stimulus in the rat.

  Psychopharmacology 20070201

• Impact of pharmacometric reviews on new drug approval and labeling decisions--a survey of 31 new drug applications submitted between 2005 and 2006.

  Clinical pharmacology and therapeutics 20070201

• Drug approvals.

  The Nurse practitioner 20070201

• Varenicline for smoking cessation.

  Expert review of neurotherapeutics 20070201

• Varenicline: new treatment with efficacy in smoking cessation.

  Drugs of today (Barcelona, Spain : 1998) 20070201

• [Drug of the month. Varenicline (Champix)].

  Revue medicale de Liege 20070201

• [Champix has become a registered drug].

  Orvosi hetilap 20070128

• Nicotine receptor partial agonists for smoking cessation.

  The Cochrane database of systematic reviews 20070124

• Mechanism of varenicline (clinical ramifications): electron transfer and oxidative stress.

  Medical hypotheses 20070101

• Oral varenicline for smoking cessation.

  The Annals of pharmacotherapy 20070101

• Non-nicotinic therapies for smoking cessation.

  Annual review of pharmacology and toxicology 20070101

• A clinical imperative: assisting patients who smoke to reduce their risk of cardiovascular disease.

  Preventive cardiology 20070101

• Smoking cessation pharmacotherapy--nicotine and non-nicotine preparations.

  Preventive cardiology 20070101

• Maximizing smoking cessation in clinical practice: pharmacologic and behavioral interventions.

  Preventive cardiology 20070101

• [Tobacco use prevention and cessation in the dental practice].

  Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia 20070101

• Varenicline: a selective alpha4beta2 nicotinic acetylcholine receptor partial agonist approved for smoking cessation.

  Cardiology in review 20070101

• [Varenicline (Champix)].

  Journal de pharmacie de Belgique 20070101

• Alcohol history and smoking cessation in nicotine replacement therapy, bupropion sustained release and varenicline trials: a review.

  Alcohol and alcoholism (Oxford, Oxfordshire) 20070101

• Kicking butts: smoking cessation update.

  Missouri medicine 20070101

• [Varenicline: an aid to smoking cessation therapy].

  Revue medicale de Bruxelles 20070101

• [Varenicline--a new chance for smokers?].

  Przeglad lekarski 20070101

• Efficacy of varenicline for smoking cessation.

  JAMA 20061206

• Multiple-dose pharmacokinetics of the selective nicotinic receptor partial agonist, varenicline, in healthy smokers.

  Journal of clinical pharmacology 20061201

• Trials that matter: varenicline: a designer drug to help smokers quit.

  Annals of internal medicine 20061121

• Pharmacokinetics, safety, and tolerability after single and multiple oral doses of varenicline in elderly smokers.

  Journal of clinical pharmacology 20061101

• New prescription drug available to help smokers stop.

  Mayo Clinic health letter (English ed.) 20061001

• Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors.

  Molecular pharmacology 20060901

• Single-dose pharmacokinetics of varenicline, a selective nicotinic receptor partial agonist, in healthy smokers and nonsmokers.

  Journal of clinical pharmacology 20060901

• New weapon to curb smoking: no more excuses to delay treatment.

  Archives of internal medicine 20060801

• Smoking cessation with varenicline, a selective alpha4beta2 nicotinic receptor partial agonist: results from a 7-week, randomized, placebo- and bupropion-controlled trial with 1-year follow-up.

  Archives of internal medicine 20060801

• Efficacy and safety of the novel selective nicotinic acetylcholine receptor partial agonist, varenicline, for smoking cessation.

  Archives of internal medicine 20060801

• Varenicline (Chantix) for tobacco dependence.

  The Medical letter on drugs and therapeutics 20060801

• Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial.

  JAMA 20060705

• Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial.

  JAMA 20060705

• Effect of maintenance therapy with varenicline on smoking cessation: a randomized controlled trial.

  JAMA 20060705

• Varenicline for smoking cessation: definite promise, but no panacea.

  JAMA 20060705

• Varenicline.

  Nature reviews. Drug discovery 20060701

• The neurobiological basis for partial agonist treatment of nicotine dependence.

  International journal of clinical practice 20060501

• The neurobiological basis for partial agonist treatment of nicotine dependence: varenicline.

  International journal of clinical practice 20060501

• Molecule of the Month. Varenicline tartrate.

  Drug news & perspectives 20060401

• Pharmacologic interventions for smoking cessation.

  Critical care nursing clinics of North America 20060301

• FDA speeds smoking cessation drug review.

  JAMA 20060208

• Metabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitro.

  Drug metabolism and disposition: the biological fate of chemicals 20060101

• New drugs: varenicline tartrate, insulin glulisine, and insulin detemir.

  Journal of the American Pharmacists Association : JAPhA 20060101

• Varenicline: a review of its use as an aid to smoking cessation therapy.

  CNS drugs 20060101

• Effectiveness of smoking cessation therapies: a systematic review and meta-analysis.

  BMC public health 20060101

• [New tobacco dependence drug: Varenicline, partial agonist of alpha4beta2 acetylcholine-nicotine receptors].

  Casopis lekaru ceskych 20060101

• The FDA approves new drug for smoking cessation.

  FDA consumer 20060101

• Smoking cessation efficacy and safety of varenicline, an alpha4beta2 nicotinic receptor partial agonist.

  The Journal of cardiovascular nursing 20060101

• Varenicline (CHANTIX): a stop-smoking pill.

  ORL-head and neck nursing : official journal of the Society of Otorhinolaryngology and Head-Neck Nurses 20060101

• [Medication for ending tobacco dependency. Current state].

  Atencion primaria 20050630

• Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation.

  Journal of medicinal chemistry 20050519

• Revealing the multidimensional framework of the Minnesota nicotine withdrawal scale.

  Current medical research and opinion 20050501