38083-17-9 | 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$25.00	$17.00
5g	98%	in stock	$25.00	$18.00
25g	98%	in stock	$57.00	$40.00
50g	98%	in stock	$101.00	$71.00
100g	98%	in stock	$161.00	$113.00
500g	98%	in stock	$485.00	$340.00

Description

• Catalog Number: AB45758
• Chemical Name: 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one
• CAS Number: 38083-17-9
• Molecular Formula: C15H17ClN2O2
• Molecular Weight: 292.7607
• MDL Number: MFCD00055505
• SMILES: Clc1ccc(cc1)OC(C(=O)C(C)(C)C)n1cncc1
• NSC Number: 759808

Computed Properties

• Complexity: 335
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Undefined Atom Stereocenter Count: 1
• XLogP3: 3.7

Literature

• Efficacy of a piroctone olamine/climbazol shampoo in comparison with a zinc pyrithione shampoo in subjects with moderate to severe dandruff.

  International journal of cosmetic science 20110601

• Evaluation of the genotoxicity of the imidazole antifungal climbazole: comparison to published results for other azole compounds.

  Mutation research 20090101

• [Determination of antidangdruff agent salicylic acid, zinc pyrithione, octopirox, climbazole and ketoconazole in shampoo by high performance liquid chromatography].

  Wei sheng yan jiu = Journal of hygiene research 20050901

• Induction and inhibition of cytochrome P450 and drug-metabolizing enzymes by climbazole.

  Biological & pharmaceutical bulletin 20020101

• [Clinical effectiveness and tolerance of climbazole containing dandruff shampoo in patients with seborrheic scalp eczema].

  Praxis 20010816

• Climbazole is a new potent inducer of rat hepatic cytochrome P450.

  The Journal of toxicological sciences 20010801