38609-97-1 | 9-Oxo-10(9H)-acridineacetic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	99%	in stock	$20.00	$14.00
5g	99%	in stock	$24.00	$17.00
10g	99%	in stock	$38.00	$27.00
25g	99%	in stock	$76.00	$53.00
100g	99%	in stock	$264.00	$185.00

Description

• Catalog Number: AF67063
• Chemical Name: 9-Oxo-10(9H)-acridineacetic acid
• CAS Number: 38609-97-1
• Molecular Formula: C15H11NO3
• Molecular Weight: 253.25274
• MDL Number: MFCD00157050
• SMILES: OC(=O)Cn1c2ccccc2c(=O)c2c1cccc2

Computed Properties

• Complexity: 356
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 2.7

Literature

• [Apoptosis of the hypothalamus neurosecretory cells in stress and ageing: the role of immune modulators].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20120401

• [Pathogenetic ground of including reamberin and cycloferon combination into the therapy program for patients with severe cases of acute tonsillitis of a mixed viral/bacterial etiology].

  Georgian medical news 20120301

• [Dose-dependent interferon-induction activity and pharmacokinetics of cycloferon in healthy humans].

  Eksperimental'naia i klinicheskaia farmakologiia 20120101

• [Proteomic profile and non-specific immunoprophylaxis of respiratory diseases in frequently sick children].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20120101

• [Interferon status in the treatment of neuroleptic-resistant patients with paranoid schizophrenia].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101

• [Evaluation of safety and pharmacotherapeutic efficacy of cycloferon in treatment of Astrakhan rickettsial fever].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20120101

• [A new technique for local immunotherapy of allergic rhinosinusitis--intranasal aerosol therapy with the use of a cycloferon solution].

  Vestnik otorinolaringologii 20120101

• [Cycloferon in the complex therapy of patients with widespread forms of pulmonary tuberculosis].

  Eksperimental'naia i klinicheskaia farmakologiia 20120101

• [Aproaches to immunotherapy in different immunophenotypes of cutaneous basal cell carcinoma].

  Voprosy onkologii 20120101

• [Relationship between the endogenous interferon IFN-gamma level and risk of hepatotoxic liver damage in tuberculosis patients].

  Eksperimental'naia i klinicheskaia farmakologiia 20120101

• [Efficacy of antiviral agents in the treatment of Crimean hemorrhagic fever].

  Klinicheskaia meditsina 20120101

• [The cytokine status as a criterion for the efficacy of intranasal aerosol therapy with the use of a cycloferon solution in the patients presenting with allergic rhinosinusitis].

  Vestnik otorinolaringologii 20120101

• [Cycloferon use in complex therapy of children with salmonellosis and yersiniosis infection].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20120101

• [Immunotropic agents in therapy of chronic degenerative diseases of the vulva].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20120101

• [Influence of immunotropic preparation cycloferon and phytopreparations of Cynara scolimus L. on blood cytokines profile of the patients with chronic viral hepatitis C in medical rehabilitation period].

  Likars'ka sprava 20120101

• [New possibilities for elimination of human papillomavirus from the organism].

  Georgian medical news 20110301

• [Using cycloferon in complex therapy of patients with cutaneous vasculitis (clinical and immunological rationale)].

  Eksperimental'naia i klinicheskaia farmakologiia 20110101

• [Effect of immunomodulator cycloferon on quality of life and psychoemotional state of patients with chronic active brucellosis subjected to complex pharmacotherapy].

  Eksperimental'naia i klinicheskaia farmakologiia 20110101

• [Pathogenesis and treatment of patients after polytrauma].

  Urologiia (Moscow, Russia : 1999) 20110101

• [Cycloferon in emergency prophylaxis of respiratory viral infections and influenza].

  Klinicheskaia meditsina 20110101

• [Cycloferon administration in chronic pyelonephritis: changes in interferon status].

  Terapevticheskii arkhiv 20110101

• [Possibilities of using interferon-induction therapy during latent HBV infection].

  Eksperimental'naia i klinicheskaia farmakologiia 20110101

• [Problems in treating influenza and acute respiratory infection in children].

  Eksperimental'naia i klinicheskaia farmakologiia 20110101

• [Minimization of endogenous intoxication syndrome by individual choice of drugs for therapy of chronic hepatitis].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

• [Dynamics of interferon status in patients with atopic dermatitis during standard therapy combined with cycloferon].

  Klinicheskaia meditsina 20110101

• [Treatment of chlamydial infection in chronic prostatitis].

  Urologiia (Moscow, Russia : 1999) 20110101

• [Clinicoimmunological monitoring of therapy in patients with associated forms of yersiniosis].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

• [Manifestations of immune deficiency in children with perinatal HIV infection in the treatment dynamics].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

• [Improvement of treatment of inflammatory diseases in oral cavity].

  Eksperimental'naia i klinicheskaia farmakologiia 20110101

• [Peculiarities of immunomodulating therapy in an immunocompromised patient with allergies].

  Klinicheskaia meditsina 20110101

• [Infectious mononucleosis: etiology, immunological variants, methods of correction].

  Eksperimental'naia i klinicheskaia farmakologiia 20110101

• [Perspectives of prevention and treatment of herpes symplex with regular recurrence].

  Terapevticheskii arkhiv 20110101

• [Investigation of luromarin efficacy on mice with experimental tick-borne encephalitis].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

• [Characteristics of immune response to etiotropic and pathogenetic therapy in children with chronic hepatitis C].

  Eksperimental'naia i klinicheskaia farmakologiia 20110101

• [Efficacy of the combination of cycloferon and reamberin in treatment of resistant patients with paranoid schizophrenia].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

• [Therapeutic efficacy of various formulations of cycloferon in the treatment of infectious mononucleosis in children].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

• [Clinical efficacy of cycloferon in complex therapy of infectious mononucleosis in pediatrics].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

• [Efficiency of modern immunoactive preparation cycloferon at coplex therapy of the patients with nonalcoholic steatohepatitis combined with irritable bowel syndrome].

  Likars'ka sprava 20110101

• [Combined therapy of patients with recurring anogenital herpes infection].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

• [Chemotherapy of chronic viral hepatitis B: randomized multicenter investigation results].

  Eksperimental'naia i klinicheskaia farmakologiia 20101101

• [Combined cycloferon treatment of tuberculosis in patients infected with HIV].

  Eksperimental'naia i klinicheskaia farmakologiia 20100701

• [Use of immunomodulators in the therapy of chronic hepatitis C: improving standard approach].

  Eksperimental'naia i klinicheskaia farmakologiia 20100401

• [Improvement of parodontitis therapy of patients with HIV-infection].

  Stomatologiia 20100101

• [Clinical efficiency of the use of interferon inductors in surgical patients].

  Khirurgiia 20100101

• [Parodontitis immunotropic therapy in patients with chronic viral and bacterial infections].

  Stomatologiia 20100101

• [Cycloferon efficacy in the treatment of acute respiratory tract viral infection and influenza during the morbidity outbreak in 2009-2010].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20100101

• [Efficacy of cycloferon in the treatment of brucellosis].

  Klinicheskaia meditsina 20100101

• [Pathogenetically substantiated therapy of patients with virus hepatitis C, quality of life, and the disease outcome risk (clinical survey)].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20100101

• [Correction of immunity disorders, treatment of intestinal infections and disbiosis in children (clinical review)].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20100101

• [The use of cycloferon in the combined treatment of tuberculosis patients infected with HIV and viral hepatitis].

  Klinicheskaia meditsina 20100101

• [Cycloferon in complex therapy of chronic brucellosis].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20100101

• [Changes of functional activity of peripheral blood leukocytes during the immunotherapy of tick-borne infections in children].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101

• [Optimization of parodontitis treatment of patients with tuberculosis].

  Stomatologiia 20100101

• [Effectiveness of cycloferon liniment in a complex treatment, and monitoring of cytokine profile of gingival fluid of patients with paradontitis].

  Stomatologiia 20100101

• [Clinical laboratory approaches to parodontitis treatment optimization].

  Stomatologiia 20100101

• [The cytokine profile in the acute period of tick-borne neuroinfections in children].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101

• [Efficiency of using cycloferon as part of combined therapy for chronic hepatitis C (a review of multicenter clinical trials)].

  Terapevticheskii arkhiv 20100101

• [Use of cycloferon in the treatment of patients with pulmonary tuberculosis with mild clinical manifestations].

  Terapevticheskii arkhiv 20100101

• [Optimization of prophylaxis of relapses of primary erysipelas with the use of cyclopheron].

  Klinicheskaia meditsina 20100101

• [Cycloferon efficacy of therapy of chronic hepatitis B (results of randomized multicentre study)].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20100101

• [Focal immunophysiotherapy in combined treatment of men with manifestations of papilloma virus infection].

  Urologiia (Moscow, Russia : 1999) 20100101

• [Cycloferon efficacy in viral and bacterial diseases of children (clinical review)].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20100101

• [Up-to-date approach to treatment of inflammatory infections in the maxillofacial region].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101

• [Pathogenetic therapy of tuberculosis of respiratory organs during sanatorium-and-spa treatment].

  Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury 20090101

• [Type 1 and type 2 interferon inductor (cycloferon) in therapy of children with pyelonephritis associated with herpes viruses].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101

• [Cycloferon, as an agent in the therapy and urgent prophylaxis of influenza and acute respiratory tract viral infection (multicentre randomized controlled comparative study)].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101

• [Improvement of natural resistance in children for prophylaxis of influenza and acute respiratory tract viral infections (results of multicenter randomized trials)].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101

• [Immunomodulators in the 'gold standard' of the chronic viral hepatitis C therapy].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20080101

• [Cycloferon in the treatment of infectious diseases].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20080101

• [Effect of intranasal aerosol-therapy with cycloferon on the function of respiration in patients with some forms of rhinitis].

  Georgian medical news 20070101

• Structural, spectroscopic, and magnetic study of bis(9,10-dihydro-9-oxo-10-acridineacetate)bis(imidazole)bis(methanol) nickel(II).

  Inorganic chemistry 20061225

• Apoptosis of hypothalamic neurosecretory cells in stress mice at different stages of ontogenesis.

  Neuroscience and behavioral physiology 20060601

• [Effect of aerosol therapy with cyclopheron in patients with chronic rhinitis].

  Georgian medical news 20060601

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• [Some pathogenic mechanisms of aerozol-therapy including cyclopheron treatment in patients with chronic rhinitis].

  Georgian medical news 20060501

• [Immunological and microbiological aspects of low intensity laser effect on the factors of local immunity of the reproductive tract in women with chlamydia infection].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20060101

• [Individual changes of gene expression in the interferon system in human blood cells due to amixin and cycloferon].

  Voprosy virusologii 20050101

• [Influence of cycloferon on the biological properties of bacterial intracellular pathogens].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20050101

• [Hypothalamic neurosecretory cell apoptosis during stress in mice at different stages of ontogenesis].

  Morfologiia (Saint Petersburg, Russia) 20050101

• [Cyclopheron pretreatment in opisthorchiasis management in patients with viral hepatitis C].

  Terapevticheskii arkhiv 20050101

• [The preclinical diagnosis, prevention and treatment of postoperative iridocyclitis in patients after intraocular aphakia correction].

  Vestnik oftalmologii 20040101

• [Neuroimmunopathologic aspects of epilepsy].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20040101

• [Cycloferon--a new domestic preparation for the prophylaxis of influenza and other acute respiratory viral infections].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20040101

• Direct antiviral effect of cycloferon (10-carboxymethyl-9-acridanone) against adenovirus type 6 in vitro.

  Antiviral research 20030401

• [Use of cycloferon in a combined treatment of chlamydial conjunctivitis].

  Vestnik oftalmologii 20030101

• [Cytokinin inducing and antiviral activity of cycloferon on experimental herpetic infection].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20030101

• [Neuroimmunopathological mechanisms of preclinical epileptogenesis and their correction by cycloferon].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101

• Regulation of cytokine mRNAs by interferon and interferon inducers.

  Russian journal of immunology : RJI : official journal of Russian Society of Immunology 20020701

• [Interferon status of patients with non-specific ulcerous colitis and its correction with interferon inducers].

  Terapevticheskii arkhiv 20020101

• [Pulmonary surfactant and blood serum in patients with chronic obstructive bronchitis on differentiated therapy].

  Likars'ka sprava 20020101

• [Effect of interferon inductors on infection induced by hepatitis C virus and activity of mRNA cytokines in cell cultures SW-13 and MT-4].

  Voprosy virusologii 20020101

• [Treatment of patients with invasive bladder cancer].

  Urologiia (Moscow, Russia : 1999) 20020101

• Correlations between in vitro effects of preparations of interferon and its inducers on blood cells in patients with multiple sclerosis.

  Bulletin of experimental biology and medicine 20010401

• [Increase in NK-activity using superlow doses of the immunomodulator cycloferon].

  Tsitologiia 20010101

• [Cycloferon in treating duodenal ulcers in rats].

  Eksperimental'naia i klinicheskaia farmakologiia 20010101

• HIV-1 neutralization and tumor cell proliferation inhibition in vitro by simplified analogues of pyrido[4,3,2-mn]thiazolo[5,4-b]acridine marine alkaloids.

  Journal of medicinal chemistry 19920724