39093-93-1 | Thiomorpholine 1,1-dioxide

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$13.00	$9.00
10g	98%	in stock	$22.00	$16.00
25g	98%	in stock	$52.00	$36.00
100g	98%	in stock	$200.00	$140.00

Description

• Catalog Number: AI49613
• Chemical Name: Thiomorpholine 1,1-dioxide
• CAS Number: 39093-93-1
• Molecular Formula: C4H9NO2S
• Molecular Weight: 135.1848
• MDL Number: MFCD05861623
• SMILES: O=S1(=O)CCNCC1

Computed Properties

• Complexity: 143
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• XLogP3: -1.1

Upstream Synthesis Route

Thiomorpholine 1,1-dioxide, also known as morpholine-1,1-dioxide sulfide, is a versatile chemical compound widely used in chemical synthesis applications. This compound plays a crucial role as a key building block in the synthesis of various organic molecules and pharmaceuticals. Its unique molecular structure allows it to participate in a wide range of reactions, making it a valuable reagent in the lab.One of the key applications of thiomorpholine 1,1-dioxide in chemical synthesis is its role as a sulfur-dioxide surrogate. This compound can be easily converted into sulfur dioxide under mild conditions, offering a safer and more convenient alternative for reactions that require the use of sulfur dioxide gas. By serving as a sulfur dioxide precursor, thiomorpholine 1,1-dioxide enables the efficient and controlled introduction of sulfur functionality into organic molecules.Additionally, thiomorpholine 1,1-dioxide can also act as a nucleophile in various reactions, forming important sulfur-containing intermediates that are essential for the synthesis of heterocyclic compounds and sulfur-containing polymers. Its ability to participate in both nucleophilic substitution and addition reactions makes it a versatile tool for chemists working in organic synthesis.Overall, thiomorpholine 1,1-dioxide is a valuable reagent with diverse applications in chemical synthesis, offering researchers a convenient and effective way to incorporate sulfur functionalities into their target molecules. Its unique properties and versatility make it an essential compound in the toolbox of synthetic chemists.

Literature

• Exploiting transport activity of p-glycoprotein at the blood-brain barrier for the development of peripheral cannabinoid type 1 receptor antagonists.

  Molecular pharmaceutics 20120507

• A general route to mono- and disubstituted divinyl sulfones: acyclic Michael acceptors for the synthesis of polyfunctionalized cyclic sulfones.

  The Journal of organic chemistry 20110506

• Synthesis and in vitro anti-Helicobacter pylori activity of N-[5-(5-nitro-2-heteroaryl)-1,3,4-thiadiazol-2-yl]thiomorpholines and related compounds.

  European journal of medicinal chemistry 20080801