39537-23-0 | L-Alanyl-l-glutamine

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$10.00	$7.00
25g	97%	in stock	$28.00	$19.00
500g	97%	in stock	$247.00	$173.00

Description

• Catalog Number: AD37503
• Chemical Name: L-Alanyl-l-glutamine
• CAS Number: 39537-23-0
• Molecular Formula: C8H15N3O4
• Molecular Weight: 217.2224
• MDL Number: MFCD00133046
• SMILES: NC(=O)CC[C@@H](C(=O)O)NC(=O)[C@@H](N)C

Computed Properties

• Complexity: 267
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 6
• XLogP3: -4.4

Literature

• Quantitative high-performance liquid chromatography-tandem mass spectrometry impurity profiling methods for the analysis of parenteral infusion solutions for amino acid supplementation containing L-alanyl-L-glutamine.

  Journal of chromatography. A 20121012

• Pretreatment with alanyl-glutamine suppresses T-helper-cell-associated cytokine expression and reduces inflammatory responses in mice with acute DSS-induced colitis.

  The Journal of nutritional biochemistry 20120901

• Pharmacologically dosed oral glutamine reduces myocardial injury in patients undergoing cardiac surgery: a randomized pilot feasibility trial.

  JPEN. Journal of parenteral and enteral nutrition 20120901

• Nutritional interventions for liver-transplanted patients.

  The Cochrane database of systematic reviews 20120815

• Randomized clinical trial of glutamine-supplemented versus standard parenteral nutrition in infants with surgical gastrointestinal disease.

  The British journal of surgery 20120701

• Intravenous free and dipeptide-bound glutamine maintains intestinal microcirculation in experimental endotoxemia.

  Nutrition (Burbank, Los Angeles County, Calif.) 20120501

• Novel in vitro and in vivo models and potential new therapeutics to break the vicious cycle of Cryptosporidium infection and malnutrition.

  The Journal of infectious diseases 20120501

• L-glutamine absorption is enhanced after ingestion of L-alanylglutamine compared with the free amino acid or wheat protein.

  Nutrition research (New York, N.Y.) 20120401

• Alanyl-glutamine dipeptide restores the cytoprotective stress proteome of mesothelial cells exposed to peritoneal dialysis fluids.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120301

• Abstracts of the 6th cachexia conference, milan, Italy, december 8-10, 2011 (part 2).

  Journal of cachexia, sarcopenia and muscle 20120301

• Improvements of immune status, intestinal integrity and gain performance in the early-weaned calves parenterally supplemented with L-alanyl-L-glutamine dipeptide.

  Veterinary immunology and immunopathology 20120115

• Systems analysis of the transcriptional response of human ileocecal epithelial cells to Clostridium difficile toxins and effects on cell cycle control.

  BMC systems biology 20120101

• Effects of adenosine A₂A receptor activation and alanyl-glutamine in Clostridium difficile toxin-induced ileitis in rabbits and cecitis in mice.

  BMC infectious diseases 20120101

• [Efficacy of the dipeptide N(2)-L-Alanyl-L-glutamine in traumatic patients admitted to the ICU: a prospective, randomized, double-blind, multicentre study].

  Nutricion hospitalaria 20120101

• [Efficacy of parenteral glutamine in patients undergoing bone marrow transplantation].

  Nutricion hospitalaria 20120101

• Glutamine is cardioprotective in patients with ischemic heart disease following cardiopulmonary bypass.

  The heart surgery forum 20111201

• Effect of probiotic bacteria on microbial host defense, growth, and immune function in human immunodeficiency virus type-1 infection.

  Nutrients 20111201

• Glutamine as an immunonutrient.

  Yonsei medical journal 20111101

• Alanyl-glutamine restores maternal deprivation-induced TLR4 levels in a rat neonatal model.

  Clinical nutrition (Edinburgh, Scotland) 20111001

• Alanyl-glutamine promotes intestinal epithelial cell homeostasis in vitro and in a murine model of weanling undernutrition.

  American journal of physiology. Gastrointestinal and liver physiology 20111001

• Quantification of l-alanyl-l-glutamine in mammalian cell culture broth: Evaluation of different detectors.

  Analytical biochemistry 20110901

• The effect of L-alanyl-L-glutamine dipeptide supplemented total parenteral nutrition on infectious morbidity and insulin sensitivity in critically ill patients.

  Critical care medicine 20110601

• Glutamine: the struggle for proof?

  Critical care medicine 20110601

• Dynamic pH junction-sweeping for on-line focusing of dipeptides in capillary electrophoresis with laser-induced fluorescence detection.

  The Analyst 20110507

• Pyruvate: immunonutritional effects on neutrophil intracellular amino or alpha-keto acid profiles and reactive oxygen species production.

  Amino acids 20110401

• Reduction of liver ischemia-reperfusion injury via glutamine pretreatment.

  The Journal of surgical research 20110301

• The midgut transcriptome of Phlebotomus (Larroussius) perniciosus, a vector of Leishmania infantum: comparison of sugar fed and blood fed sand flies.

  BMC genomics 20110101

• A hepatoprotective Lindera obtusiloba extract suppresses growth and attenuates insulin like growth factor-1 receptor signaling and NF-kappaB activity in human liver cancer cell lines.

  BMC complementary and alternative medicine 20110101

• PreImplantation Factor (PIF) correlates with early mammalian embryo development-bovine and murine models.

  Reproductive biology and endocrinology : RB&E 20110101

• Increased frequency of spontaneous neoplastic transformation in progeny of bystander cells from cultures exposed to densely ionizing radiation.

  PloS one 20110101

• Leucine supplementation improves adiponectin and total cholesterol concentrations despite the lack of changes in adiposity or glucose homeostasis in rats previously exposed to a high-fat diet.

  Nutrition & metabolism 20110101

• Preconditioning with L-alanyl-glutamine reduces hepatic ischemia-reperfusion injury in rats.

  Acta cirurgica brasileira 20110101

• Preconditioning with L-alanyl-L-glutamine in a Mongolian gerbil model of acute cerebral ischemia/reperfusion injury.

  Acta cirurgica brasileira 20110101

• L-alanyl-glutamine dipeptide pretreatment attenuates ischemia-reperfusion injury in rat testis.

  Acta cirurgica brasileira 20110101

• Effect of glutamine on the mRNA level of key enzymes of malate-aspartate shuttle in the rat intestine subjected to ischemia reperfusion.

  Acta cirurgica brasileira 20110101

• L-alanyl-glutamine pretreatment attenuates acute inflammatory response in children submitted to palatoplasty.

  Acta cirurgica brasileira 20110101

• Effect of intravenous GLutamine supplementation IN Trauma patients receiving enteral nutrition study protocol (GLINT Study): a prospective, blinded, randomised, placebo-controlled clinical trial.

  BMJ open 20110101

• Kinetically controlled enzymatic synthesis of dipeptide precursor of L-alanyl-L-glutamine.

  Biotechnology and applied biochemistry 20110101

• Glutamine supplementation in sick children: is it beneficial?

  Journal of nutrition and metabolism 20110101

• The formation of actin waves during regeneration after axonal lesion is enhanced by BDNF.

  Scientific reports 20110101

• Metabolic changes induced by pre-administration of L-alanyl-glutamine and omega-3 in Wistar rats subjected to sepsis.

  Acta cirurgica brasileira 20101201

• Randomized clinical trial of gut-specific nutrients in critically ill surgical patients.

  The British journal of surgery 20101101

• Effects of in ovo injecting disaccharides and alanyl-glutamine dipeptide on the energy status in duck embryos and neonates.

  Animal reproduction science 20101001

• Glutamate exocrine dynamics augmented by plasma glutamine and the distribution of amino acid transporters of the rat pancreas.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100601

• L-alanyl-glutamine preoperative infusion in patients with critical limb ischemia subjected to distal revascularization reduces tissue damage and protects from oxidative stress.

  Annals of vascular surgery 20100501

• Effect of multidrug-efflux transporter genes on dipeptide resistance and overproduction in Escherichia coli.

  FEMS microbiology letters 20100301

• Effects of supplementation with free glutamine and the dipeptide alanyl-glutamine on parameters of muscle damage and inflammation in rats submitted to prolonged exercise.

  Cell biochemistry and function 20100101

• Examination of the efficacy of acute L-alanyl-L-glutamine ingestion during hydration stress in endurance exercise.

  Journal of the International Society of Sports Nutrition 20100101

• Amino acids change liver growth factors gene expression in malnourished rats.

  Nutricion hospitalaria 20100101

• Parenteral nutrition: Revisited.

  Indian journal of anaesthesia 20100101

• Evaluation of HIV protease and nucleoside reverse transcriptase inhibitors on proliferation, necrosis, apoptosis in intestinal epithelial cells and electrolyte and water transport and epithelial barrier function in mice.

  BMC gastroenterology 20100101

• The impact of glutamine dipeptide-supplemented parenteral nutrition on outcomes of surgical patients: a meta-analysis of randomized clinical trials.

  JPEN. Journal of parenteral and enteral nutrition 20100101

• Immunogenicity and efficacy of oral vaccines in developing countries: lessons from a live cholera vaccine.

  BMC biology 20100101

• Nutrition support with glutamine dipeptide in patients undergoing liver transplantation.

  Transplantation proceedings 20091201

• Glutamine and alanyl-glutamine dipeptide reduce mesenteric plasma extravasation, leukocyte adhesion and tumor necrosis factor-α (TNF-α) release during experimental endotoxemia.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20091201

• Clinical trial: prophylactic intravenous alanyl-glutamine reduces the severity of gastrointestinal toxicity induced by chemotherapy--a randomized crossover study.

  Alimentary pharmacology & therapeutics 20090901

• The effect of intravenous alanyl-glutamine supplementation on plasma glutathione levels in intensive care unit trauma patients receiving enteral nutrition: the results of a randomized controlled trial.

  Anesthesia and analgesia 20090801

• Protective effects of glutamine dipeptide and alpha-tocopherol against ischemia-reperfusion injury in the isolated rat liver.

  Clinical nutrition (Edinburgh, Scotland) 20090601

• L-Glutamine or L-alanyl-L-glutamine prevents oxidant- or endotoxin-induced death of neonatal enterocytes.

  Amino acids 20090501

• Effects of oral supplementation with glutamine and alanyl-glutamine on glutamine, glutamate, and glutathione status in trained rats and subjected to long-duration exercise.

  Nutrition (Burbank, Los Angeles County, Calif.) 20090401

• Perioperative application of L-alanyl-L-glutamine in cardiac surgery: effect on the polarized T cell cytokine expression.

  Amino acids 20090301

• Intravenous glutamine decreases lung and distal organ injury in an experimental model of abdominal sepsis.

  Critical care (London, England) 20090101

• Modulation of B-cell endoplasmic reticulum calcium homeostasis by Epstein-Barr virus latent membrane protein-1.

  Molecular cancer 20090101

• Amino acids - Guidelines on Parenteral Nutrition, Chapter 4.

  German medical science : GMS e-journal 20090101

• Surgery and transplantation - Guidelines on Parenteral Nutrition, Chapter 18.

  German medical science : GMS e-journal 20090101

• Protective effects of alanyl-glutamine on acute lung injury induced by lipopolysaccharide in rats.

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20081201

• The role of parenteral glutamine supplement for surgical patient perioperatively: result of a single center, prospective and controlled study.

  Langenbeck's archives of surgery 20081101

• Alanyl-glutamine and glutamine supplementation improves 5-fluorouracil-induced intestinal epithelium damage in vitro.

  Digestive diseases and sciences 20081001

• Frequent intravenous pulses of growth hormone together with glutamine supplementation in prolonged critical illness after multiple trauma: effects on nitrogen balance, insulin resistance, and substrate oxidation.

  Critical care medicine 20080601

• Hartree-Fock calculations with linearly scaling memory usage.

  The Journal of chemical physics 20080514

• Metabolic effects of enteral versus parenteral alanyl-glutamine dipeptide administration in critically ill patients receiving enteral feeding: a pilot study.

  Clinical nutrition (Edinburgh, Scotland) 20080401

• Safety studies of l-alanyl-l-glutamine (l-AG).

  Regulatory toxicology and pharmacology : RTP 20080301

• Glutamine and alanyl-glutamine accelerate the recovery from 5-fluorouracil-induced experimental oral mucositis in hamster.

  Cancer chemotherapy and pharmacology 20080201

• Frequent intravenous pulses of growth hormone together with alanylglutamine supplementation in prolonged critical illness after multiple trauma: effects on glucose control, plasma IGF-I and glutamine.

  Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20080201

• Year in review in Intensive Care Medicine, 2007. I. Experimental studies. Clinical studies: brain injury and neurology, renal failure and endocrinology.

  Intensive care medicine 20080201

• Impact of alanyl-glutamine dipeptide on severe acute pancreatitis in early stage.

  World journal of gastroenterology 20080121

• Depletion of plasma antioxidants in surgical intensive care unit patients requiring parenteral feeding: effects of parenteral nutrition with or without alanyl-glutamine dipeptide supplementation.

  Nutrition (Burbank, Los Angeles County, Calif.) 20080101

• [Effect of glutamine on serum interleukin-8 and tumor necrosis factor-alpha levels in patients with severe pancreatitis].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080101

• [Objectivization of the diagnostics and control of treatment of paresis of the gastrointestinal tract in diffuse peritonitis].

  Vestnik khirurgii imeni I. I. Grekova 20080101

• Efficacy of parenteral nutrition supplemented with glutamine dipeptide to decrease hospital infections in critically ill surgical patients.

  JPEN. Journal of parenteral and enteral nutrition 20080101

• L-alanyl-L-glutamine-supplemented parenteral nutrition decreases infectious morbidity rate in patients with severe acute pancreatitis.

  JPEN. Journal of parenteral and enteral nutrition 20080101

• Pilot Study: effects of parenteral glutamine dipeptide supplementation on neutrophil functions and prevention of chemotherapy-induced side-effects in acute myeloid leukaemia patients.

  The Journal of international medical research 20080101

• L-alanine-L-glutamine supplementation improves the outcome after colorectal surgery for cancer.

  Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20071101

• Short-term alanyl-glutamine dipeptide pretreatment in liver ischemia-reperfusion model: effects on microcirculation and antioxidant status in rats.

  Clinical nutrition (Edinburgh, Scotland) 20071001

• Pathways involved in alanyl-glutamine-induced changes in neutrophil amino- and alpha-keto acid homeostasis or immunocompetence.

  Amino acids 20070901

• Specific amino acids in the critically ill patient--exogenous glutamine/arginine: a common denominator?

  Critical care medicine 20070901

• [Effect of early enriched parenteral alanyl-glutamine on heat shock protein 70 (HSP70) expression in critical patients].

  Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20070801

• L-alanin-L-glutamine supplementation improves the outcome after colorectal surgery for cancer.

  Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20070701

• Toward a feline-optimized culture medium: impact of ions, carbohydrates, essential amino acids, vitamins, and serum on development and metabolism of in vitro fertilization-derived feline embryos relative to embryos grown in vivo.

  Biology of reproduction 20070501

• Glutamine kinetics during intravenous glutamine supplementation in ICU patients on continuous renal replacement therapy.

  Intensive care medicine 20070401

• Wasting and intestinal barrier function in children taking alanyl-glutamine-supplemented enteral formula.

  Journal of pediatric gastroenterology and nutrition 20070301

• Glutamine induces heat-shock protein and protects against Escherichia coli lipopolysaccharide-induced vascular hyporeactivity in rats.

  Critical care (London, England) 20070101

• A controlled trial of glutamine effects on bone healing.

  Advances in therapy 20070101

• Glutamine dipeptide for parenteral nutrition in abdominal surgery: a meta-analysis of randomized controlled trials.

  World journal of gastroenterology 20061214

• [Effect of glutamine on apoptosis of the small intestine in young rats with endotoxemia and its mechanism].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20061201

• Metabolic effects of l-alanyl-glutamine in burned rats.

  Burns : journal of the International Society for Burn Injuries 20060901

• Double-blinded, placebo-controlled trial on intravenous L-alanyl-L-glutamine in the incidence of oral mucositis following chemoradiotherapy in patients with head-and-neck cancer.

  International journal of radiation oncology, biology, physics 20060801

• [The prospective study on application of parenteral nutrition with alanyl-glutamine dipeptide in chemotherapy of gastrointestinal neoplasms patients].

  Ai zheng = Aizheng = Chinese journal of cancer 20060801

• [The clinical efficacy of glutamine dipeptides on postoperative patients: an updated systematic review of randomized controlled trials from Europe and Asia (1997 - 2005)].

  Zhonghua yi xue za zhi 20060620

• Effect of alanyl-glutamine supplementation on plasma and tissue glutamine concentrations in rats submitted to exhaustive exercise.

  Nutrition (Burbank, Los Angeles County, Calif.) 20060501

• Alanyl-glutamine dipeptide inhibits hepatic ischemia-reperfusion injury in rats.

  World journal of gastroenterology 20060307

• L-alanyl-L-glutamine dipeptide-supplemented total parenteral nutrition reduces infectious complications and glucose intolerance in critically ill patients: the French controlled, randomized, double-blind, multicenter study.

  Critical care medicine 20060301

• Glutamine-containing parenteral nutrition: Another piece in the jigsaw?

  Critical care medicine 20060301

• Parenterally administered dipeptide alanyl-glutamine prevents worsening of insulin sensitivity in multiple-trauma patients.

  Critical care medicine 20060201

• Caspase and bid involvement in Clostridium difficile toxin A-induced apoptosis and modulation of toxin A effects by glutamine and alanyl-glutamine in vivo and in vitro.

  Infection and immunity 20060101

• Alterations in neutrophil (PMN) free intracellular alpha-keto acid profiles and immune functions induced by L-alanyl-L-glutamine, arginine or taurine.

  Amino acids 20051101

• Elimination kinetics of L-alanyl-L-glutamine in ICU patients.

  Amino acids 20051101

• Glutamine-enriched total parenteral nutrition in patients with inflammatory bowel disease.

  European journal of clinical nutrition 20051101

• Intestinal renal metabolism of L-citrulline and L-arginine following enteral or parenteral infusion of L-alanyl-L-[2,15N]glutamine or L-[2,15N]glutamine in mice.

  American journal of physiology. Gastrointestinal and liver physiology 20051001

• Paradoxical toxicity of cardioplegic compounds on ischemic cardiomyocyte using optimal design strategy.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050701

• Clostridium difficile toxin A induces intestinal epithelial cell apoptosis and damage: role of Gln and Ala-Gln in toxin A effects.

  Digestive diseases and sciences 20050701

• The feeding route (enteral or parenteral) affects the plasma response of the dipetide Ala-Gln and the amino acids glutamine, citrulline and arginine, with the administration of Ala-Gln in preoperative patients.

  The British journal of nutrition 20050701

• A novel and efficient enzymatic method for the production of peptides from unprotected starting materials.

  Journal of biotechnology 20050126

• The effect of preventive use of alanyl-glutamine on diaphragm muscle function in cecal ligation and puncture-induced sepsis model.

  JPEN. Journal of parenteral and enteral nutrition 20050101

• Of glutamine and arginine.

  JPEN. Journal of parenteral and enteral nutrition 20050101

• Effects of parenteral nutrition supplemented with alanyl-glutamine on nutrition status in rats.

  JPEN. Journal of parenteral and enteral nutrition 20050101

• Effects of L-alanyl-glutamine upon the blood and kidney biochemical parameters in the rat hind limb model of ischemia/reperfusion.

  Acta cirurgica brasileira 20050101

• Alanyl-glutamine hastens morphologic recovery from 5-fluorouracil-induced mucositis in mice.

  Nutrition (Burbank, Los Angeles County, Calif.) 20041001

• Enhanced effect of glycyl-L-glutamine on mouse preimplantation embryos in vitro.

  Reproductive biomedicine online 20040701

• Diarrhea and reduced levels of antiretroviral drugs: improvement with glutamine or alanyl-glutamine in a randomized controlled trial in northeast Brazil.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040615

• Glutamine parenteral supplementation in stem cell transplant.

  Bone marrow transplantation 20040201

• L-alanyl-L-glutamine-supplemented parenteral nutrition improves infectious morbidity in secondary peritonitis.

  Clinical nutrition (Edinburgh, Scotland) 20040201

• Enteral alanyl-glutamine supplement promotes intestinal adaptation in rats.

  International journal of molecular medicine 20031001

• Effects of dipeptide administration on hypoglycaemic counterregulation in type 1 diabetes.

  Diabetes & metabolism 20030901

• Nutritional benefits of enteral alanyl-glutamine supplementation on rat small intestinal damage induced by cyclophosphamide.

  Journal of gastroenterology and hepatology 20030601

• Perioperative GLY-GLN infusion diminishes the surgery-induced period of immunosuppression: accelerated restoration of the lipopolysaccharide-stimulated tumor necrosis factor-alpha response.

  Annals of surgery 20030101

• Alanyl-glutamine-supplemented parenteral nutrition prevents intestinal ischemia-reperfusion injury in rats.

  JPEN. Journal of parenteral and enteral nutrition 20030101

• Effect of glutamine dipeptide on hepatic regeneration in partially hepatectomized malnourished rats.

  Nutrition (Burbank, Los Angeles County, Calif.) 20030101

• Nutrition support to patients undergoing gastrointestinal surgery.

  Nutrition journal 20030101

• Standardized parenteral alanyl-glutamine dipeptide supplementation is not beneficial in autologous transplant patients: a randomized, double-blind, placebo controlled study.

  Bone marrow transplantation 20021201

• [The effects of glutamine dipeptide on the improvement of endotoxemia in severely burned patients].

  Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20021201

• [Parenteral glutamine does not improve the nutritional status in patients during high-dose chemotherapy and autologous peripheral stem cell transplantation].

  Vnitrni lekarstvi 20021101

• Parenteral L-alanyl-L-glutamine improves 6-month outcome in critically ill patients.

  Critical care medicine 20020901

• The role of L-alanyl-L-glutamine in the immune response in vitro.

  Wiener klinische Wochenschrift 20020830

• Effects of an alanyl-glutamine-based oral rehydration and nutrition therapy solution on electrolyte and water absorption in a rat model of secretory diarrhea induced by cholera toxin.

  Nutrition (Burbank, Los Angeles County, Calif.) 20020601

• The effect of glutamine-supplemented total parenteral nutrition on nitrogen economy depends on severity of diseases in surgical patients.

  Clinical nutrition (Edinburgh, Scotland) 20020601

• The local vascular tolerance to an intravenous infusion of a concentrated glutamine solution in ICU patients.

  Clinical nutrition (Edinburgh, Scotland) 20020401

• Effects of arginine, L-alanyl-L-glutamine or taurine on neutrophil (PMN) free amino acid profiles and immune functions in vitro.

  Amino acids 20020101

• Effect of alanyl-glutamine on leucine and protein metabolism in irradiated rats.

  Amino acids 20020101

• Gut glutamine metabolism at different stages of sepsis in rats.

  Surgery today 20020101

• Glutamine transporter in crypts compensates for loss of villus absorption in bovine cryptosporidiosis.

  American journal of physiology. Gastrointestinal and liver physiology 20010901

• Postoperative glycyl-glutamine infusion reduces immunosuppression: partial prevention of the surgery induced decrease in HLA-DR expression on monocytes.

  Clinical nutrition (Edinburgh, Scotland) 20010201

• Alanyl-glutamine enriched total parenteral nutrition improves local, systemic, and remote organ responses to intraperitoneal bacterial challenge.

  JPEN. Journal of parenteral and enteral nutrition 20010101

• The impact of alanyl-glutamine on clinical safety, nitrogen balance, intestinal permeability, and clinical outcome in postoperative patients: a randomized, double-blind, controlled study of 120 patients.

  JPEN. Journal of parenteral and enteral nutrition 19990101

• Total parenteral nutrition with glutamine dipeptide after major abdominal surgery: a randomized, double-blind, controlled study.

  Annals of surgery 19980201