4005-49-6 | N-(9H-Purin-6-yl)benzamide

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$5.00	$4.00
10g	98%	in stock	$7.00	$5.00
25g	98%	in stock	$15.00	$11.00
100g	98%	in stock	$56.00	$40.00

Description

• Catalog Number: AB46629
• Chemical Name: N-(9H-Purin-6-yl)benzamide
• CAS Number: 4005-49-6
• Molecular Formula: C12H9N5O
• Molecular Weight: 239.2328
• MDL Number: MFCD00037927
• SMILES: O=C(c1ccccc1)NC1=NC=NC2=NC=NC12
• NSC Number: 98641

Computed Properties

• Complexity: 305
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 1.3

Literature

• Synthesis and biological evaluation of 3'-C-ethynyl and 3'-C-(1,4-disubstituted-1,2,3-triazolo) double-headed pyranonucleosides.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20120501

• Synthesis of 4,6-dideoxy-3-fluoro-2-keto-beta-D-glucopyranosyl analogues of 5-fluorouracil, N6-benzoyl adenine, uracil, thymine, N4-benzoyl cytosine and evaluation of their antitumor activities.

  Bioorganic chemistry 20100401

• Unsaturated dideoxy fluoro-ketopyranosyl nucleosides as new cytostatic agents: a convenient synthesis of 2,6-dideoxy-3-fluoro-4-keto-beta-D-glucopyranosyl analogues of uracil, 5-fluorouracil, thymine, N4-benzoyl cytosine and N6-benzoyl adenine.

  European journal of medicinal chemistry 20091101

• One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening.

  Journal of medicinal chemistry 20090723

• Unsaturated fluoro-ketopyranosyl nucleosides: synthesis and biological evaluation of 3-fluoro-4-keto-beta-d-glucopyranosyl derivatives of N(4)-benzoyl cytosine and N(6)-benzoyl adenine.

  European journal of medicinal chemistry 20080201

• Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol.

  BMC biochemistry 20070101

• An enzymatic transglycosylation of purine bases.

  Nucleosides, nucleotides & nucleic acids 20070101

• Short synthesis of octosyl nucleosides.

  Organic letters 20060330

• 6-(N-benzoylamino)purine as a novel and potent inhibitor of xanthine oxidase: inhibition mechanism and molecular modeling studies.

  Journal of enzyme inhibition and medicinal chemistry 20050801

• 2'-chloro-2',3'-dideoxy-3'-fluoro-d-ribonucleosides: synthesis, stereospecificity, some chemical transformations, and conformational analysis.

  The Journal of organic chemistry 20030725

• Stereoselective synthesis of the beta-anomer of 4'-thionucleosides based on electrophilic glycosidation to 4-thiofuranoid glycals.

  The Journal of organic chemistry 20020823

• Diastereocontrolled synthesis of dinucleoside phosphorothioates using a novel class of activators, dialkyl(cyanomethyl)ammonium tetrafluoroborates.

  Journal of the American Chemical Society 20020508

• Synthesis and cytotoxicity of cyanoborane adducts of n6-benzoyladenine and 6-triphenylphosphonylpurine.

  Metal-based drugs 20020101

• The adenine derivative of alpha-L-LNA (alpha-L-ribo configured locked nucleic acid): synthesis and high-affinity hybridization towards DNA, RNA, LNA and alpha-L-LNA complementary sequences.

  Bioorganic & medicinal chemistry letters 20010409